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    <entry>
        <source releaseDate="2004-12-01Z">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
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            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
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                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
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        </source>
        <experimentList>
            <experimentDescription id="165305">
                <names>
                    <shortLabel>millward-1998-1</shortLabel>
                    <fullName>Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins.</fullName>
                </names>
                <bibref>
                    <xref>
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                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>affinity chrom</shortLabel>
                        <fullName>affinity chromatography technology</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Affinity purification</alias>
                        <alias typeAc="MI:1041" type="synonym">Affinity purification</alias>
                        <alias typeAc="MI:1041" type="synonym">affinity chrom</alias>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Millward TA., Heizmann CW., Schafer BW., Hemmings BA.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">Affinity resin - S100B agarose</attribute>
                    <attribute name="journal" nameAc="MI:0885">EMBO J. (0261-4189)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">1998</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="165306">
                <names>
                    <shortLabel>s100b_bovin</shortLabel>
                    <fullName>Protein S100-B</fullName>
                    <alias typeAc="MI:0301" type="gene name">S100B</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">S100 calcium-binding protein B</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">S-100 protein subunit beta</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">S-100 protein beta chain</alias>
                </names>
                <xref>
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                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="9913">
                    <names>
                        <shortLabel>bovin</shortLabel>
                        <fullName>Bos taurus (Bovine)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Bovine</alias>
                    </names>
                </organism>
                <sequence>MSELEKAVVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDSDGDGECDFQEFMAFVAMITTACHEFFEHE</sequence>
            </interactor>
            <interactor id="165307">
                <names>
                    <shortLabel>stk38_human</shortLabel>
                    <fullName>Serine/threonine-protein kinase 38</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">NDR1</alias>
                    <alias typeAc="MI:0301" type="gene name">STK38</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">NDR1 protein kinase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Nuclear Dbf2-related kinase 1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q15208" version="SP_63" refType="identity" refTypeAc="MI:0356"/>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
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                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAMTGSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDILKPTVATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="165308">
                <names>
                    <shortLabel>stk38-s100b-3</shortLabel>
                    <fullName>Interaction between STK38 and S100B demonstrated by affinity chromatography</fullName>
                </names>
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                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-458501" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
                <experimentList>
                    <experimentRef>165305</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="165309">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-458502" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>165306</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="165310">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-458503" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>165307</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">Interaction results in activation of STK38</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
