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                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
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                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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            <experimentDescription id="134739">
                <names>
                    <shortLabel>thut-1997-1</shortLabel>
                    <fullName>Repression of p53-mediated transcription by MDM2: a dual mechanism.</fullName>
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                            <fullName>In vitro</fullName>
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                        <shortLabel>pull down</shortLabel>
                        <fullName>pull down</fullName>
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                    <names>
                        <shortLabel>polyclonal western</shortLabel>
                        <fullName>polyclonal antibody western blot</fullName>
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                    <attribute name="author-list" nameAc="MI:0636">Thut CJ., Goodrich JA., Tjian R.</attribute>
                    <attribute name="journal" nameAc="MI:0885">Genes Dev. (0890-9369)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">1997</attribute>
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                    <shortLabel>mdm2_human</shortLabel>
                    <fullName>E3 ubiquitin-protein ligase Mdm2</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">p53-binding protein Mdm2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Oncoprotein Mdm2</alias>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OC8" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3TU1" version="SP_260"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K2S6" version="SP_121" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045184" secondary="establishment of protein localization" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3TJ2" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007089" secondary="traversing start control point of mitotic cell cycle" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6T2E" version="SP_260"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198323" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LAW" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Q9L" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048545" secondary="response to steroid hormone" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JVE" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GGN" version="SP_260"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001265391.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BIT" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043278" secondary="response to morphine" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2RUH" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061663" secondary="NEDD8 ligase activity" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046677" secondary="response to antibiotic" version="SP_260"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036443" version="SP_260"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001841" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_260"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004842" secondary="ubiquitin-protein transferase activity" version="SP_260"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000353611"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019789" secondary="SUMO transferase activity" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4XXB" version="SP_260"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016567" secondary="protein ubiquitination" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2MPS" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3V3B" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LN2" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LAZ" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902254" secondary="negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C6B" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JVR" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001568" secondary="blood vessel development" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060411" secondary="cardiac septum morphogenesis" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VK0" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZYF" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7AD0" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HMK" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2F1Y" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MNJ" version="SP_260"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-392N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_260"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000393413"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ODF" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6T2F" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4OGV" version="SP_260"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3JZS" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043021" secondary="ribonucleoprotein complex binding" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SQO" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097718" secondary="disordered domain specific binding" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" secondary="protein domain specific binding" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7BJ0" version="SP_260"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001876" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LBK" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LAV" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045931" secondary="positive regulation of mitotic cell cycle" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MDN" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006511" secondary="ubiquitin-dependent protein catabolic process" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3TPX" version="SP_260"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000360430"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804760" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0047485" secondary="protein N-terminus binding" version="SP_260"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000135679" version="SP_260" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034504" secondary="protein localization to nucleus" version="SP_260"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941858" version="SP_260"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061630" secondary="ubiquitin protein ligase activity" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UMN" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LNJ" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FOP" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JWR" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C6A" version="SP_260"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990000" secondary="amyloid fibril formation" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EQS" version="SP_260"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5674400" version="SP_260"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000444430" version="SP_260" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Z1M" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Q9O" version="SP_260"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5C5A" version="SP_260"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DIJ" version="SP_260"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP</sequence>
            </interactor>
            <interactor id="134741">
                <names>
                    <shortLabel>tbp_human</shortLabel>
                    <fullName>TATA-box-binding protein</fullName>
                    <alias typeAc="MI:0301" type="gene name">TBP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TF2D</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TFIID</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">GTF2D1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TATA-box factor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TATA-binding factor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TATA sequence-binding protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Transcription initiation factor TFIID TBP subunit</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P20226" version="SP_106" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EGJ" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-73776" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1C9B" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EG8" version="SP_237"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-1078N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001939" secondary="female pronucleus" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140223" secondary="general transcription initiation factor activity" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EGA" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-749476" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005669" secondary="transcription factor TFIID complex" version="SP_237"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000230354" version="SP_237" refType="transcript"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P20226" version="SP_237"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6MZL" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NVU" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NVZ" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001046" secondary="core promoter sequence-specific DNA binding" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017162" secondary="aryl hydrocarbon receptor binding" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" secondary="transcription factor binding" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_237"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-76042" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000995" secondary="RNA polymerase III general transcription initiation factor activity" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006383" secondary="transcription by RNA polymerase III" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NVS" version="SP_237"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1056192" refType="intact-secondary"/>
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                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16845" version="SP_106" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9018519" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_237"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000112592" version="SP_237" refType="gene"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7LBM" version="SP_237"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-11019728" refType="intact-secondary"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000375942"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ROD" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_237"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UC02" version="SP_106" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000392092" version="SP_237" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000442132"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-167161" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EGE" version="SP_237"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000230354" version="SP_237" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IYA" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EGC" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-427413" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001093" secondary="TFIIB-class transcription factor binding" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" secondary="DNA-binding transcription factor binding" version="SP_237"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4E3B3" version="SP_158" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016251" secondary="RNA polymerase II general transcription initiation factor activity" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NVP" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-73772" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006352" secondary="DNA-templated transcription, initiation" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-73779" version="SP_237"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-355371" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IYC" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NW0" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6807505" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-75953" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EG7" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1TGH" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001091" secondary="RNA polymerase II general transcription initiation factor binding" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1JFI" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NVR" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-76066" version="SP_237"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-674695" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_237"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001165556.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_237"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003185.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7ENA" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007283" secondary="spermatogenesis" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6MZM" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NVT" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005672" secondary="transcription factor TFIIA complex" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IY7" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EDX" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051123" secondary="RNA polymerase II preinitiation complex assembly" version="SP_237"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030491" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6O9L" version="SP_237"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6IBM6" version="SP_113" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6MZD" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-167172" version="SP_237"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000540980"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000230354"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-76071" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-73762" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IYD" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EGF" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006367" secondary="transcription initiation from RNA polymerase II promoter" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IY9" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7ENC" version="SP_237"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012295" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-76061" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097550" secondary="transcription preinitiation complex" version="SP_237"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000814" version="SP_237"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000375942" version="SP_237" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7NVY" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ROC" version="SP_237"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="F5H869" version="SP_158" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5FUR" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-167162" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-427359" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EG9" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000979" secondary="RNA polymerase II core promoter sequence-specific DNA binding" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EGB" version="SP_237"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-73863" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7EGD" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006366" secondary="transcription by RNA polymerase II" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IYB" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001940" secondary="male pronucleus" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5N9G" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000791" secondary="euchromatin" version="SP_237"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ROE" version="SP_237"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_237"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="134742">
                <names>
                    <shortLabel>mdm2-tbp-1</shortLabel>
                    <fullName>the inhibitory domain of MDM2 interacts with both the 34K subunit of TFIIE and TBP.</fullName>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-389723" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>134739</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="134743">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-389724" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>134740</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="511693">
                                <names>
                                    <shortLabel>ecobb</shortLabel>
                                    <fullName>Escherichia coli (strain B / BL21)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="134744">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-389725" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>134741</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="511693">
                                <names>
                                    <shortLabel>ecobb</shortLabel>
                                    <fullName>Escherichia coli (strain B / BL21)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
