IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ liu-1999-1 Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Liu LX., Janvier K., Berteaux-Lecellier V., Cartier N., Benarous R., Aubourg P. J. Biol. Chem. (0021-9258) 1999 liu-1999-2 Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters. mouse-3t3 Mus musculus embryo cells 3t3 Mouse embryo fibroblast cells coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip western blot western blot Immuno blot Immuno blot Liu LX., Janvier K., Berteaux-Lecellier V., Cartier N., Benarous R., Aubourg P. J. Biol. Chem. (0021-9258) 1999 abcd1_human ATP-binding cassette sub-family D member 1 ABCD1 Adrenoleukodystrophy protein ALD protein protein human Homo sapiens Human MPVLSRPRPWRGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAPAGEPTQEASGVAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQVFEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST abcd2_mouse ATP-binding cassette sub-family D member 2 Abcd2 Aldr Adrenoleukodystrophy-related protein protein protein mouse Mus musculus Mouse MIHMLNAAAYRVKWTRSGAAKRAACLVAAAYALKTLYPIIGKRLKQPGHRKAKAEAYSPAENREILHCTEIICKKPAPGLNAAFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGSLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSSCGLIMVAIPIITATGFADGDLEDGPKQAMVSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRTVTQEPENHSKRGGNLELPLSDTLAIKGTVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIQTAEKTS abcd3_human ATP-binding cassette sub-family D member 3 ABCD3 PMP70 PXMP1 70 kDa peroxisomal membrane protein protein protein human Homo sapiens Human MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS abcd1_mouse ATP-binding cassette sub-family D member 1 Abcd1 Ald Aldgh Adrenoleukodystrophy protein protein protein mouse Mus musculus Mouse MPVLSTPRPSRVTTLKRTAVVLALTAYGVHKIYPLVRQCLTPARGPQVPAGEPTQEASGATATKAGMNRVFLQRLLALLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYAESDSEAMKKAALEMKEEELVSERTEAFTIARNLLTAAADATERIMSSYKEVTELAGYTARVYEMFQVFEDVKHCRFKRTGDLEEAQAGPGVMVQSGVHVEGPLKIQGQVVDVEQGIICENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYSGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRHILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQGRLQELRQILGEAAAPVQPLVPGVPT abcd3_mouse ATP-binding cassette sub-family D member 3 Abcd3 Pmp70 Pxmp1 70 kDa peroxisomal membrane protein 68 kDa peroxisomal membrane protein protein protein mouse Mus musculus Mouse MAAFSKYLTARNTSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVDKVFLSRLSQILKIMVPRTFCKETGYLLLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSSKDFKRYLFNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTRYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLLVSGLFLTRLRRPIGKMTIMEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTIHSVFRKLVEHLHNFIFFRFSMGFIDSIIAKYVATVVGYLVVSRPFLDLAHPRHLHSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGRYERTMVSQQEKGIEGAQASPLVPGAGEIINTDNIIKFDHVPLATPNGDILIQDLSFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGKEDQKKRGISDQVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKKITEDTVEFGS abcd1-abcd1-1 Interaction detected by Y2H. 16866 N/A 16868 unspecified role unspecified role bait bait N/A 16868 unspecified role unspecified role prey prey physical association physical association false false false residues 631-745 used in the interaction. pro-484 and arg-591 important in the interaction. abcd2-abcd2-2 Interaction of proteins detected by Y2H. 16866 N/A 16869 unspecified role unspecified role bait bait N/A 16869 unspecified role unspecified role prey prey physical association physical association false false false Residues 374-742 used in teh interaction. abcd1-abcd2-2 Interaction of the mouse and human protein detected by Y2H. 16866 N/A 16869 unspecified role unspecified role prey prey N/A 16868 unspecified role unspecified role bait bait physical association physical association false false false residues 631-745 of human protein and 374-742 of mouse protein used in the interaction. pro-484 and arg-591 in the human ABCD1 important in the interaction. abcd3-abcd3-1 Interaction detected by Y2H. 16866 N/A 16870 unspecified role unspecified role bait bait N/A 16870 unspecified role unspecified role prey prey physical association physical association false false false Residues 338-660 used in the studies. abcd3-abcd1-1 Interaction between human proteins studied by Y2H. 16866 N/A 16870 unspecified role unspecified role bait bait N/A 16868 unspecified role unspecified role prey prey physical association physical association false false false ABCD3 residues 338-660 and ALDP residues 631-745 used in the interaction studies. pro-484 and arg-591 important in the interaction. abcd3-abcd2-2 Interaction between human and mouse proteins detected by Y2H. 16866 N/A 16870 unspecified role unspecified role bait bait N/A 16869 unspecified role unspecified role prey prey physical association physical association false false false ABCD3 residues 338-660 and ABCD2 residues 374-742 used in the studies. abcd1-abcd1-2 Interaction determined by CoIP 16867 N/A 16868 unspecified role unspecified role bait bait N/A 16868 unspecified role unspecified role prey prey physical association physical association false false false abcd1-abcd3-2 Interaction determined by CoIP. 16867 N/A 16868 unspecified role unspecified role bait bait N/A 16870 unspecified role unspecified role prey prey physical association physical association false false false abcd1-abcd2-1 Interaction determined by CoIP. 16867 N/A 16871 unspecified role unspecified role bait bait N/A 16868 unspecified role unspecified role prey prey physical association physical association false false false abcd1-abcd1-3 Interaction determined by CoIP. 16867 N/A 16868 unspecified role unspecified role bait bait N/A 16871 unspecified role unspecified role prey prey physical association physical association false false false abcd3-abcd1-3 Interaction detected by CoIP. 16867 N/A 16872 unspecified role unspecified role bait bait N/A 16868 unspecified role unspecified role prey prey physical association physical association false false false abcd3-abcd2-3 Interaction detected by CoIP. 16867 N/A 16872 unspecified role unspecified role bait bait N/A 16869 unspecified role unspecified role prey prey physical association physical association false false false