MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint cartaud-1998-1 Evidence for in situ and in vitro association between beta-dystroglycan and the subsynaptic 43K rapsyn protein. Consequence for acetylcholine receptor clustering at the synapse. in vivo in vivo crosslink cross-linking study crosslink predetermined predetermined participant predetermined Cartaud A., Coutant S., Petrucci TC., Cartaud J. J. Biol. Chem. (0021-9258) 1998 cartaud-1998-2 Evidence for in situ and in vitro association between beta-dystroglycan and the subsynaptic 43K rapsyn protein. Consequence for acetylcholine receptor clustering at the synapse. in vitro In vitro filter binding filter binding Filter overlay assay Filter overlay assay predetermined predetermined participant predetermined Cartaud A., Coutant S., Petrucci TC., Cartaud J. J. Biol. Chem. (0021-9258) 1998 cartaud-1998-3 Evidence for in situ and in vitro association between beta-dystroglycan and the subsynaptic 43K rapsyn protein. Consequence for acetylcholine receptor clustering at the synapse. in vitro In vitro pull down pull down predetermined predetermined participant predetermined Cartaud A., Coutant S., Petrucci TC., Cartaud J. J. Biol. Chem. (0021-9258) 1998 rapsn_tetcf 43 kDa receptor-associated protein of the synapse RAPSN Acetylcholine receptor-associated 43 kDa protein 43 kDa postsynaptic protein protein protein tetcf Torpedo californica (Pacific electric ray) Pacific electric ray Torpedo californica MGQDQTKQQIEKGLQLYQANETGKALEIWQQVVERSTELPGRFRALGCLITAHSEMGKYEDMLRFAVAQSEAARQMGDPERVTEAYLNLARGHEKLCEFSEAVAYCRTCLGAEGGPLRLQFNGQVCLSMGNAFLGLSAFQKALECFEKALRYAHGNDDKMLECRVCCSLGAFYVQLKDYEKALFFPCKSAELVADYGRGWSLKYKAMSRYHMAAAYRKLGRMDDAMECCEESMKIALQHQDRPLQALCLLCFADIHRHRSDIGKALPRYESSLNIMTEIGNRLGQAHVLLNIAKCWMTEKKLDKTLGVVQKAEELADAVGNKLVLLKAHCLYETIYREMGSDQLLRDHVVKFHECMEDMELYCGLCGESIGDQNSQLQALPCSHLFHLKCLQTNGNRGCPNCKRSSVKPGYV mint Thought to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin dag1_rabit Dystroglycan 1 DAG1 Dystrophin-associated glycoprotein 1 Dystroglycan protein protein rabit Oryctolagus cuniculus (Rabbit) Rabbit MRMSVGLSLLLPLWGRTFLLLLCVAVAQSHWPSEPSEAVRDWENQLEASMHSVLSDLHEALPTVVGIPDGTAVVGRSFRVTIPTDLIGSSGEVIKVSTAGKEVLPSWLHWDPQSHTLEGLPLDTDKGVHYISVSAAQLDANGSHIPQTSSVFSIEVYPEDHSEPQSVRAASPDLGEAAASACAAEEPVTVLTVILDADLTKMTPKQRIDLLHRMQSFSEVELHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCSLNQNSVPDIRGVEAPAREGTMSAQLGYPVVGWHIANKKPPLPKRIRRQIHATPTPVTAIGPPTTAIQEPPSRIVPTPTSPAIAPPTETMAPPVRDPVPGKPTVTTRTRGAIIQTPTLGPIQPTRVSDAGTVVSGQIRATVTIPGYVEPTAVATPPTTTTKKPRVSTPKPATPSTDSSATTTRRPTKKPRTPRPVPRVTTKAPITRLETASPPTRIRTTTSGVPRGGEPNQRPELKNHIDRVDAWVGTYFEVKIPSDTFYDKEDTTTDKLKLTLKLREQQLVGEKSWVQFNSNSQLMYGLPDSSHVGKHEYFMHATDKGGLSAVDAFEIHVHKRPQGDKAPARFKAKFVGDPAPVVNDIHKKIALVKKLAFAFGDRNCSTVTLQNITRGSIVVEWTNNTLPLEPCPKEQITGLSRRIAEDNGQPRPAFTNALEPDFKATSIAITGSGSCRHLQFIPVAPPGIPSSVTPPTEVPDRDPEKSSEDDVYLHTVIPAVVVAAILLIAGIIAMICYRKKRKGKLTLEDQATFIKKGVPIIFADELDDSKPPPSSSMPLILQEEKAPLPPPEYPSQSVPETTPLNQDTVGEYTPLRDEDPNAPPYQPPPPFTAPMEGKGSRPKNMTPYRSPPPYVPP mint Forms part of the dystrophin-associated protein complex (DAPC) which may link the cytoskeleton to the extracellular matrix dag1-rapsn 8606 rapsn_torca 8609 unspecified role unspecified role unspecified role unspecified role physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 dag1_rabit 8610 unspecified role unspecified role unspecified role unspecified role physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false JUXTA MEMBRANE REGION Stoichiometry: 1.0 physical association physical association false false false mint dag1-rapsn-1 8607 rapsn_torca 8609 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 dag1_rabit 8610 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false JUXTA MEMBRANE REGION Stoichiometry: 1.0 direct interaction direct interaction false false false mint dag1-rapsn-2 8608 rapsn_torca 8609 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 dag1_rabit 8610 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false JUXTA MEMBRANE REGION Stoichiometry: 1.0 direct interaction direct interaction false false false mint