MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint iwata-1998-1 Alpha1-syntrophin has distinct binding sites for actin and calmodulin. in vitro In vitro experimental interac experimental interaction detection experimental interac predetermined predetermined participant predetermined Iwata Y., Pan Y., Yoshida T., Hanada H., Shigekawa M. FEBS Lett. (0014-5793) 1998 iwata-1998-2 Alpha1-syntrophin has distinct binding sites for actin and calmodulin. in vitro In vitro pull down pull down predetermined predetermined participant predetermined Iwata Y., Pan Y., Yoshida T., Hanada H., Shigekawa M. FEBS Lett. (0014-5793) 1998 iwata-1998-3 Alpha1-syntrophin has distinct binding sites for actin and calmodulin. in vitro In vitro filter binding filter binding Filter overlay assay Filter overlay assay predetermined predetermined participant predetermined Iwata Y., Pan Y., Yoshida T., Hanada H., Shigekawa M. FEBS Lett. (0014-5793) 1998 snta1_rabit Alpha-1-syntrophin SNTA1 SNT1 59-1 DAP Syntrophin-1 59 kDa dystrophin-associated protein A1 acidic component 1 protein protein rabit Oryctolagus cuniculus (Rabbit) Rabbit MASGRRAPRTGLLELRAGTGAGAGGERWQRVLVSLAEDALTVSPADGEPGPEPGAVREPEPAQINGAAEPGAAPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQALKKTGKEVVLEVKYMKEVSPYFKNSAGGTSVGWDSPPASPLQRQPSSPGPQTRNLSEAKHVPLKMAYVSRRCTPSDPEHRYLEICSADGQDTIFLRAKDEASARSWAGAIQAQINALLPWVKDELQALLAASSPAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYGGLPQTREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTACTWNGRPCNLSVHIDKGFTLWAAEPGAARAVLLRQPFEKLQMSSDDGASLLFLDFGGAEGEIQLDLHSCPKTMVFIIHSFLSAKVTRLGLLA mint Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-biphosphate acta_rabit Actin, aortic smooth muscle Alpha-actin-2 ACTA2 ACTSA ACTVS protein protein rabit Oryctolagus cuniculus (Rabbit) Rabbit MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF calm_oryla Calmodulin-A calm1 protein protein oryla Oryzias latipes (Medaka fish) Japanese ricefish EQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV fragmentation type: fragment Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases mint acta2-snta1 8633 snta1_rabit 8636 unspecified role unspecified role unspecified role unspecified role purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false SU Stoichiometry: 1.0 acta_rabit 8637 unspecified role unspecified role unspecified role unspecified role purified purified Stoichiometry: 1.0 association association false false false mint acta2-snta1-1 8633 snta1_rabit 8636 unspecified role unspecified role unspecified role unspecified role purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false Stoichiometry: 1.0 acta_rabit 8637 unspecified role unspecified role unspecified role unspecified role purified purified Stoichiometry: 1.0 association association false false false other techniques: co-sedimentation mint calm1-snta1 8633 snta1_rabit 8636 unspecified role unspecified role unspecified role unspecified role purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false Stoichiometry: 1.0 calm_oryla 8638 unspecified role unspecified role unspecified role unspecified role purified purified Stoichiometry: 1.0 association association false false false other techniques: analysis of the fluorescence emission spectra of dansyl-CaM mint calm1-snta1-1 8633 calm_oryla 8638 unspecified role unspecified role unspecified role unspecified role purified purified Stoichiometry: 1.0 snta1_rabit 8636 unspecified role unspecified role unspecified role unspecified role purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false Stoichiometry: 1.0 association association false false false other techniques: analysis of the fluorescence emission spectra of dansyl-CaM mint snta1-calm1 8634 snta1_rabit 8636 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false Stoichiometry: 1.0 calm_oryla 8638 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction false false false other techniques: analysis of the fluorescence emission spectra of dansyl-CaM mint snta1-calm1-1 8634 calm_oryla 8638 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 snta1_rabit 8636 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false Stoichiometry: 1.0 direct interaction direct interaction false false false other techniques: analysis of the fluorescence emission spectra of dansyl-CaM mint snta1-acta2 8635 snta1_rabit 8636 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false SU Stoichiometry: 1.0 acta_rabit 8637 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction false false false mint snta1-acta2-1 8635 snta1_rabit 8636 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false Stoichiometry: 1.0 acta_rabit 8637 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction false false false other techniques: co-sedimentation mint