<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="17135203" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579228" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="168116">
                <names>
                    <shortLabel>yoo-2004-1</shortLabel>
                    <fullName>The carboxy-terminus of the hepatitis B virus X protein is necessary and sufficient for the activation of hypoxia-inducible factor-1alpha.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="15527772" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-1209328" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-13943" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1016/j.febslet.2004.10.004" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="15527772" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7371192" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-5217286" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-nih_3t3</shortLabel>
                            <fullName>Mus musculus Swiss NIH 3t3 embryo fibroblast cells</fullName>
                        </names>
                        <cellType>
                            <names>
                                <shortLabel>nih_3t3</shortLabel>
                                <fullName>Mouse Swiss NIH embryo contact inhibited fibroblast cells</fullName>
                            </names>
                            <xref>
                                <primaryRef db="intact" dbAc="MI:0469" id="IA:0081" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="cabri" dbAc="MI:0246" id="ECACC 93061524" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-347326" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1780131" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </cellType>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti tag coip</shortLabel>
                        <fullName>anti tag coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0007" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-90" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Yoo YG., Cho S., Park S., Lee MO.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
                    <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2004</attribute>
                    <attribute name="imex-exported"/>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="168117">
                <names>
                    <shortLabel>q7tdy3_hbv</shortLabel>
                    <fullName>Protein X</fullName>
                    <alias typeAc="MI:0301" type="gene name">X</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HBx</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Peptide X</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">pX</alias>
                    <alias typeAc="MI:0306" type="orf name">HBVgp3</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q7TDY3" version="TrEMBL_19" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033650" secondary="host cell mitochondrion" version="TrEMBL_95"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050434" secondary="positive regulation of viral transcription" version="TrEMBL_95"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-1209331" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="TrEMBL_95"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000347" secondary="positive regulation of hepatocyte proliferation" version="TrEMBL_95"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006351" secondary="transcription, DNA-templated" version="TrEMBL_95"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7371213" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0039652" secondary="activation by virus of host NF-kappaB transcription factor activity" version="TrEMBL_95"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042025" secondary="host cell nucleus" version="TrEMBL_95"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000236" version="TrEMBL_95"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019079" secondary="viral genome replication" version="TrEMBL_95"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0039592" secondary="suppression by virus of G2/M transition of host mitotic cell cycle" version="TrEMBL_95"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10407">
                    <names>
                        <shortLabel>hbv</shortLabel>
                        <fullName>Hepatitis B virus (HBV)</fullName>
                        <alias typeAc="MI:1041" type="synonym">HBV</alias>
                    </names>
                </organism>
                <sequence>MAARLCCQLDPARDVLCLRPVGAESRGRPLPGPLGALPPASPPVVPTDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHRNLPKVLHKRTLGLSAMSTTDLEAYFKDCVFTEWEELGEEVRLKVFVLGGCRHKLVCSPAPCNFFTSA</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interactor>
            <interactor id="168118">
                <names>
                    <shortLabel>hif1a_human</shortLabel>
                    <fullName>Hypoxia-inducible factor 1-alpha</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">ARNT-interacting protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Member of PAS protein 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Basic-helix-loop-helix-PAS protein MOP1</alias>
                    <alias typeAc="MI:0301" type="gene name">HIF1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MOP1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">BHLHE78</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PASD8</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PAS domain-containing protein 8</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Class E basic helix-loop-helix protein 78</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q16665" version="SP_99" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019896" secondary="axonal transport of mitochondrion" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036638" version="SP_241"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000337138" version="SP_241" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1234174" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000977" secondary="RNA polymerase II transcription regulatory region sequence-specific DNA binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5689880" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1234158" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006089" secondary="lactate metabolic process" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051216" secondary="cartilage development" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8857538" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016604" secondary="nuclear body" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_241"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000323326"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045648" secondary="positive regulation of erythrocyte differentiation" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007595" secondary="lactation" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903715" secondary="regulation of aerobic respiration" version="SP_241"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000323441"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000437955"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002248" secondary="connective tissue replacement involved in inflammatory response wound healing" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" secondary="regulation of transcription, DNA-templated" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900017" secondary="positive regulation of cytokine production involved in inflammatory response" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1234176" version="SP_241"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="C0LZJ3" version="SP_156" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" secondary="DNA-binding transcription factor activity, RNA polymerase II-specific" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048546" secondary="digestive tract morphogenesis" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061298" secondary="retina vasculature development in camera-type eye" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008542" secondary="visual learning" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5L9V" version="SP_241"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000100644" version="SP_241" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016607" secondary="nuclear speck" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H2L" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016922" secondary="nuclear receptor binding" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HQR" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013655" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1L8C" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1L3E" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006879" secondary="cellular iron ion homeostasis" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030502" secondary="negative regulation of bone mineralization" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051541" secondary="elastin metabolic process" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-400253" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" secondary="transcription factor binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014850" secondary="response to muscle activity" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070244" secondary="negative regulation of thymocyte apoptotic process" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002052" secondary="positive regulation of neuroblast proliferation" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010573" secondary="vascular endothelial growth factor production" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001223" secondary="transcription coactivator binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001938" secondary="positive regulation of endothelial cell proliferation" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043619" secondary="regulation of transcription from RNA polymerase II promoter in response to oxidative stress" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001947" secondary="heart looping" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042541" secondary="hemoglobin biosynthetic process" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8951664" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GFX" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HQU" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032909" secondary="regulation of transforming growth factor beta2 production" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011598" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001837" secondary="epithelial to mesenchymal transition" version="SP_241"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53XP6" version="SP_99" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0021502" secondary="neural fold elevation formation" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JWP" version="SP_241"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001521.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014887" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" secondary="DNA-binding transcription activator activity, RNA polymerase II-specific" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001922" secondary="B-1 B cell homeostasis" version="SP_241"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UPB1" version="SP_99" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006110" secondary="regulation of glycolytic process" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6785807" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051000" secondary="positive regulation of nitric-oxide synthase activity" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" secondary="protein domain specific binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071347" secondary="cellular response to interleukin-1" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8849473" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GMR" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003151" secondary="outflow tract morphogenesis" version="SP_241"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96PT9" version="SP_99" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR021537" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030949" secondary="positive regulation of vascular endothelial growth factor receptor signaling pathway" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LA9" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031514" secondary="motile cilium" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032007" secondary="negative regulation of TOR signaling" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902895" secondary="positive regulation of pri-miRNA transcription by RNA polymerase II" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YW3" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903599" secondary="positive regulation of autophagy of mitochondrion" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ILM" version="SP_241"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000338018" version="SP_241" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061419" secondary="positive regulation of transcription from RNA polymerase II promoter in response to hypoxia" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032722" secondary="positive regulation of chemokine production" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" secondary="transcription regulator complex" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090575" secondary="RNA polymerase II transcription regulator complex" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035965" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H2K" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001610" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001525" secondary="angiogenesis" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060574" secondary="intestinal epithelial cell maturation" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061030" secondary="epithelial cell differentiation involved in mammary gland alveolus development" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H2M" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098586" secondary="cellular response to virus" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4H6J" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0021987" secondary="cerebral cortex development" version="SP_241"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-447269" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010039" secondary="response to iron ion" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010634" secondary="positive regulation of epithelial cell migration" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001678" secondary="cellular glucose homeostasis" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045821" secondary="positive regulation of glycolytic process" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016239" secondary="positive regulation of macroautophagy" version="SP_241"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q16665" version="SP_241"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000338018"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001755" secondary="neural crest cell migration" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071542" secondary="dopaminergic neuron differentiation" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045926" secondary="negative regulation of growth" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001216" secondary="DNA-binding transcription activator activity" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904115" secondary="axon cytoplasm" version="SP_241"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2122947" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070888" secondary="E-box binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001054" secondary="negative regulation of mesenchymal cell apoptotic process" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046716" secondary="muscle cell cellular homeostasis" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046886" secondary="positive regulation of hormone biosynthetic process" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097411" secondary="hypoxia-inducible factor-1alpha signaling pathway" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000273" secondary="positive regulation of signaling receptor activity" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000302" secondary="response to reactive oxygen species" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035162" secondary="embryonic hemopoiesis" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001321" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043536" secondary="positive regulation of blood vessel endothelial cell migration" version="SP_241"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000539097"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_851397.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001230013.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032963" secondary="collagen metabolic process" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045766" secondary="positive regulation of angiogenesis" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LAS" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035774" secondary="positive regulation of insulin secretion involved in cellular response to glucose stimulus" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070101" secondary="positive regulation of chemokine-mediated signaling pathway" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071456" secondary="cellular response to hypoxia" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000378" secondary="negative regulation of reactive oxygen species metabolic process" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1LQB" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" secondary="DNA-binding transcription factor activity" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061072" secondary="iris morphogenesis" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013767" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000434" secondary="regulation of protein neddylation" version="SP_241"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29722N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002039" secondary="p53 binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010575" secondary="positive regulation of vascular endothelial growth factor production" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032364" secondary="oxygen homeostasis" version="SP_241"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000014" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1D7G" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010468" secondary="regulation of gene expression" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" secondary="protein heterodimerization activity" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051879" secondary="Hsp90 protein binding" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042826" secondary="histone deacetylase binding" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1LM8" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4AJY" version="SP_241"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5L9B" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903377" secondary="negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003208" secondary="cardiac ventricle morphogenesis" version="SP_241"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001892" secondary="embryonic placenta development" version="SP_241"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLEPNPESLELSFTMPQIQDQTPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTVTVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPYRDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRKRKMEHDGSLFQAVGIGTLLQQPDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-13943-1" id="168119">
                <names>
                    <shortLabel>hif1a-x</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-50790" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7371250" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-13943-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>168116</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="168120">
                        <names>
                            <shortLabel>q7tdy3_hbv</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-1209342" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7371257" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>168117</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>nucleotide sequence</shortLabel>
                                    <fullName>nucleotide sequence identification</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">sequence cloning</alias>
                                    <alias typeAc="MI:1041" type="synonym">nucleotide sequence</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>over-expressed</shortLabel>
                                    <fullName>over expressed level</fullName>
                                    <alias typeAc="MI:1041" type="synonym">over-expressed</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="168121">
                                <names>
                                    <shortLabel>binding site</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-1209343" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7371263" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>binding region</shortLabel>
                                        <fullName>binding-associated region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">binding region</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="57"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="154"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                            <feature id="168122">
                                <names>
                                    <shortLabel>tagged molecule</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-1209345" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7371267" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>tag</shortLabel>
                                        <fullName>tag</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0507" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456738" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="168123">
                        <names>
                            <shortLabel>hif1a_human</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-1209338" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7371260" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>168118</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>monoclonal western</shortLabel>
                                    <fullName>monoclonal antibody western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">monoclonal western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0072" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-955" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F2C</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
