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    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>HPIDb</shortLabel>
                <fullName>Host Pathogen Interaction database</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1335" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6598961" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.agbase.msstate.edu/hpi/main.html</attribute>
                <attribute name="postalAddress">http://www.agbase.msstate.edu/hpi/main.html</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1430419">
                <names>
                    <shortLabel>dolganiuc-2004-3</shortLabel>
                    <fullName>Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="15521019" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6914668" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25878" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10029">
                        <names>
                            <shortLabel>crigr-cho</shortLabel>
                            <fullName>chinese hamster ovary cell line</fullName>
                        </names>
                        <cellType>
                            <names>
                                <shortLabel>cho</shortLabel>
                                <fullName>chinese hamster ovary cell line</fullName>
                            </names>
                            <xref>
                                <primaryRef db="intact" dbAc="MI:0469" id="IA:0056" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="cabri" dbAc="MI:0246" id="ECACC 85050302" refType="identity" refTypeAc="MI:0356"/>
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                                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-148088" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                            <attributeList>
                                <attribute name="comment" nameAc="MI:0612">Also called LR73 cells.</attribute>
                            </attributeList>
                        </cellType>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>confocal microscopy</shortLabel>
                        <fullName>confocal microscopy</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0663" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>immunostaining</shortLabel>
                        <fullName>immunostaining</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Dolganiuc A., Oak S., Kodys K., Golenbock D.T., Finberg R.W., Kurt-Jones E., Szabo G.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">gyongyi.szabo@umassmed.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Gastroenterology (0016-5085)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2004</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1430420">
                <names>
                    <shortLabel>tlr2_human</shortLabel>
                    <fullName>Toll-like receptor 2</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Toll/interleukin-1 receptor-like protein 4</alias>
                    <alias typeAc="MI:0301" type="gene name">TLR2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TIL4</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O60603" version="SP_82" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001875" secondary="lipopolysaccharide immune receptor activity" version="SP_224"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-168188" version="SP_224"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z7X" version="SP_224"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001305720.1"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9637628" version="SP_224"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007612" secondary="learning" version="SP_224"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044297" secondary="cell body" version="SP_224"/>
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                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-35138N"/>
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                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLLILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRAAIKS</sequence>
            </interactor>
            <interactor id="1430421">
                <names>
                    <shortLabel>p27958-pro_0000037566</shortLabel>
                    <fullName>Core protein precursor</fullName>
                </names>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                    <xref>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="63746">
                    <names>
                        <shortLabel>HCV77</shortLabel>
                        <fullName>Hepatitis C virus genotype 1a (isolate H77)</fullName>
                    </names>
                </organism>
                <sequence>STNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRPEGRTWAQPGYPWPLYGNEGCGWAGWLLSPRGSRPSWGPTDPRRRSRNLGKVIDTLTCGFADLMGYIPLVGAPLGGAARALAHGVRVLEDGVNYATGNLPGCSFSIFLLALLSCLTVPASA</sequence>
                <attributeList>
                    <attribute name="chain-seq-start">2</attribute>
                    <attribute name="chain-seq-end">191</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-25878-1" id="1430422">
                <names>
                    <shortLabel>core-tlr2-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6914676" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25878-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030430" secondary="host cell cytoplasm" refType="component" refTypeAc="MI:0354"/>
                </xref>
                <experimentList>
                    <experimentRef>1430419</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1430423">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">TLR2</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6914680" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1430420</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1430424">
                        <names>
                            <shortLabel>n/a</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">Core</alias>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6914678" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1430421</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig. 8D</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
