MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint goldstein-1992-1 The BPV-1 E5 protein, the 16 kDa membrane pore-forming protein and the PDGF receptor exist in a complex that is dependent on hydrophobic transmembrane interactions. chlae-cos_1 Chlorocebus aethiops COS-1 cells Grivet cos_1 CV-1 Simian cells (cercopithecus aethiops) transformed by SV40 coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip predetermined predetermined participant predetermined Goldstein DJ., Andresson T., Sparkowski JJ., Schlegel R. Virus - Publications including interactions involving viral proteins EMBO J. (0261-4189) 1992 rapid curation rapid curation ve5_bpv1 Protein E5 E5 protein protein bpv1 Bovine papillomavirus type 1 MPNLWFLLFLGLVAAMQLLLLLFLLLFFLVYWDHFECSCTGLPF This sequence has been withdrawn from Uniprot. 0E278099E06F2956 mint E5 can induce cellular DNA synthesis. It seems to interact with a 16 kDa cellular protein. E5 seems to activate the PDGF receptor pgfrb_human Platelet-derived growth factor receptor beta CD140 antigen-like family member B PDGFRB Beta-type platelet-derived growth factor receptor PDGFR Platelet-derived growth factor receptor 1 Beta platelet-derived growth factor receptor PDGFR1 protein protein human Homo sapiens Human MRLPGAMPALALKGELLLLSLLLLLEPQISQGLVVTPPGPELVLNVSSTFVLTCSGSAPVVWERMSQEPPQEMAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALPVPYDHQRGFSGIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIVIGNEVVNFEWTYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSAELEDSGTYTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPTVLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVLELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIVVPHSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQDEPEPEPQLELQVEPEPELEQLPDSGCPAPRAEAEDSFL vatl_human V-type proton ATPase 16 kDa proteolipid subunit ATP6V0C ATP6C ATP6L ATPL Vacuolar proton pump 16 kDa proteolipid subunit protein protein human Homo sapiens Human MSESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK vatl_bovin V-type proton ATPase 16 kDa proteolipid subunit ATP6V0C ATP6C ATP6L Vacuolar proton pump 16 kDa proteolipid subunit protein protein bovin Bos taurus (Bovine) Bovine MSEAKNGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEMIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDGISLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells mint e5-pdgfrb 742342 ve5_bpv1 742343 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate undefined mutation mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false pgfrb_human 742344 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate physical association physical association false false false F1 homomint mint atp6v0c-e5 742342 ve5_bpv1 742343 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate vatl_human 742345 unspecified role unspecified role neutral component neutral component cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association false false false F1 for p16 vacuolar ATPase it was used the human protein identifier homomint mint atp6v0c-pdgfrb 742342 vatl_human 742345 unspecified role unspecified role neutral component neutral component cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level pgfrb_human 742344 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate physical association physical association false false false F3 for p16 vacuolar ATPase it was used the human protein identifier homomint mint atp6v0c-e5-1 742342 ve5_bpv1 742343 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate vatl_human 742345 unspecified role unspecified role neutral component neutral component cell lysate cell lysate physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association false false false F5 for p16 vacuolar ATPase it was used the human protein identifier homomint mint atp6v0c-pdgfrb-1 742342 vatl_bovin 742346 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate pgfrb_human 742344 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate physical association physical association false false false F3 homomint mint e5-pdgfrb-1 742342 ve5_bpv1 742343 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate pgfrb_human 742344 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed cell lysate cell lysate physical association physical association false false false F5 f5 homomint mint