IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ kuroda-2002-1 The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip polyclonal western polyclonal antibody western blot polyclonal western Kuroda TS., Fukuda M., Ariga H., Mikoshiba K. Synapse - Interactions of proteins with an established role in the presynapse. J. Biol. Chem. (0021-9258) 2002 Chromatin - Epigenetic interactions resulting in chromatin modulation rb27a_mouse Ras-related protein Rab-27A Rab27a protein protein mouse Mus musculus Mouse MSDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGAVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISHAIEMLLDLIMKRMERCVDKSWIPEGVVRSNGHTSADQLSEEKEKGLCGC sytl1_mouse Synaptotagmin-like protein 1 Sytl1 Slp1 Exophilin-7 protein protein mouse Mus musculus Mouse MPQRGHPSQERLWALPSLPMAHGPGSEVEGLLDLSFLTEEEQEAISDVLKRDAHLRQLEEGRVSKLRASLEDPWQLKILTGDWFQEARSQRHHHAHFGSDLVRASIRRKKSPKGDQALGSDGEAEAAGEDTIEGEPESRVSIEVAAPERSTETQGPDLSSPYVPSKASEGQEEEPQDHECELEAPGEGGVQVAEADPELDPEQKAEQESQPTPAQSKATSKILENGEEAPGLGPSLDRMLSSSSSVSSLNSSTLSGSLMSLSGEEAGTVQVRGSVLFSLHYEPGTSELRVQVIQCQGLAAARRRRSDPYVKSYLLPDKQSKRKTSVKKRNLNPIFNETLRHSVQQADLPGRVLSLSVWHRESLGRNIFLGEVEVPLDTWNWDSEATWLPLQPRVPPSPDELPSRGLLSLSLKYVPAGSEGGGQPQSGELHFWVKEAQSLVPLRPGSLDTYIQCSVLPDDSRASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALASRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQTLLERPCEWVDGLLPLRTNLVPRA sytl2_mouse Synaptotagmin-like protein 2 Sytl2 Slp2 Exophilin-4 protein protein mouse Mus musculus Mouse MIDLSFLTEEEQDAILKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRRKKLPAAAEQNKDTAMRAKESWVNNVNKDAVLPPEIAVVEEPEDDTDPAGPSSSLVDPASSVIDMSQESTRTPAVSLPKQRKNPFNSPKLPEDHSLQQTKPEQSKTGKAGLFQISKEGELSESKEKSSIPDMPRQQLEKPKQTVSTEPENASHTKAPIPKARKLIYKSNDLEKDDNQSFPRQRRDSLNARGAPRGILKRNSSSSSTDSETLRLNYNLDPKSKILSPGLTIHERISEKEFSLEDDSSTSSLEPLKHVRFSAVKNELPQSPRPVLGQEVGEFTVLESDQLQNGTEDAGDIEEFQNHPELSHKTPLSHYQLVSSPSDSGREREQLMSSGSAPRDEIPCHSDILPTGPQCVESSSVINGQQEKSSHFTKLPSELSKSPSDELTQCGEPEPSQTADHSFRDHRQGSEEEHSPVLKTLERRAARKLPSKSLEDIPSDSSNQAKVDNLPEELVRSAEDDQKADQEPDTNECIPGISTVPSLPDNQFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLRRYKKSPSSLTNLSSSSGMTSLSSASGSVMSVYSGDFGNLEVKGSVQFALDYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQFLKTQKLNLSVWHRDTFKRNSFLGEVELDLETWDWDSKQNKQLKWYPLKRKTAPVALETENRGEMKLALQYVPEPSPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPVFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWVEATLPLRMLLIAKLSK sytl3_mouse Synaptotagmin-like protein 3 Sytl3 Slp3 Exophilin-6 protein protein mouse Mus musculus Mouse MAHEVDLESFKELERDIILRVLYRDQTVQSTEEERVRKLKSHLQHLRWKGAKSSSQEYKEKCCARCQRALGLLLNRGAVCQGCSHRVCSECRVFLRRTRAWKCTVCFEDRNVKIKTGEWFFEERARKFPTAGRRETAGAKLLQSYQRLSKISVVPPTPPPFSESQCSSSSRLQELGHFRGFNKSVENLFLSVTTQMRKLSKSQNDMTSEKHLLAMDPRQCVGHTERRSQSDTAVNVTSRKASTPDILKAFHQEDPKHPPDPVLKQDTPPSSPTHSAVFSGGLRHGSLISINSTCTEMGNFDNANVTGEIEFAIHYCVKSCSLEICIKTCKNLAYGEEKKRKCNPYVKTYLLPDRSSQGKRKTRVQKNTLDPTFEETLKYQVDPGQLMTRRLQVSVWHLGTLARRVFLGEVILPLAMWDFKDSTAQNARWYPLRAKAEKYEENIPQNNGELAVRAKLVLPAGPRKPQEAQEGQLALNGQLCLVVLGAKNLPVRSDGTLNSFVKGCLTLPNQQKLRVKSPVLKKQACPQWKHSFVFNGVSSSQLRQSTLELTVWDQAIFGMNDRLLGEARLGSKGGAAGCPDSGSQSKLQWHRVLSSPNLWTDMTLVLH melph_mouse Melanophilin Mlph Ln Slac2a Exophilin-3 Leaden protein Synaptotagmin-like protein 2a Slp homolog lacking C2 domains a protein protein mouse Mus musculus Mouse MGKRLDLSTLTDEEAEHVWAVVQRDFDLRRREEERLQGLKGKIQKESSKRELLSDTAHLNETHCARCLQPYRLLLNSRRQCLECSLFVCKSCSHAHPEEQGWLCDPCHLARVVKIGSLEWYYQHVRARFKRFGSAKVIRSLCGRLQGGGGSEPSLEEGNGDSEQTDEDGDLDTEARDQPLNSKKKKRLLSFRDVDFEEDSDHLVQPCSQTLGLSSVPESAHSLQSLSGEPYSEDTTSLEPEGLEETGARALGCRPSPEVQPCSPLPSGEDAHAELDSPAASCKSAFGTTAMPGTDDVRGKHLPSQYLADVDTSDEDSIQGPRAASQHSKRRARTVPETQILELNKRMSAVEHLLVHLENTVLPPSAQEPTVETHPSADTEEETLRRRLEELTSNISGSSTSSEDETKPDGTFLGGSPKVCTDTGHMETQERNPRSPGNPARPTKSTDEELSEMEDRVAMTASEVQQAESEISDIESRIAALRAAGLTVKPSGKPRRKSGIPIFLPRVTEKLDRIPKTPPADPDDQAKMPKATTAVPSLLRRKYSPSSQGVDSGSFDRKSVYRGSLTQRNPNGRRGTARHIFAKPVMAQQP exph5_mouse Exophilin-5 Exph5 Kiaa0624 Slac2b Synaptotagmin-like protein homolog lacking C2 domains b protein protein mouse Mus musculus Mouse MTKVPQGFDFSFLNEEEARKILQVLERNEELRRAEKDRISKLQKTKRDIRWLQGATGEWFEEIQRKKFCNETDVNQMLKPPLTYRLQKGMAKNDPMELQTPRSKSLINQKPSVSSRMSFRSSFASLFSFRRPAKETLKLQSPRPNRCDERVRPSASVRGTASAKIYNSPVGNQPVASVFVPKPAIMREESGMPPPWDASLLESEFFQVLDDLDNKLAQEQSSGLMNTRVPFNYGSRTQFKLSHRNSHGHSTGRQQNYHSETSNMSIYNILRPGTPREGFKTFSPRTKTIYDMYRTREPRVLKEDFMQKNAFGSASLCFDSRQRSASPATGSFTARSLHFPADTQNKSSFTPVRHQQSPKRTPLSSIIWNRSDASRHRQNQEESLGVQAPMDIDPEEQYVSPRCFQESRRYEMCHSQNAYQSYPLNVPVANAMSPDTLENSENMPFYRQSNPFARSFFSSTFRQSREQRFGQNSFWSRQEEYSSWSDFPQSRGPFPSSDKDFEMFSVEANRAPSVCSQGVPSQHWRSHSSGHGTYVFRGREDSHCWRSDFQTSPLESMDTSHVNENQHPPHFVTPVGFSITDSSCHLQSSRLDSQQGYFPVEEAVDEDPYLCGKAQTPASSFRTPFPLSPDDGRESQSSSFPDSTATLQKIIPNKPDFLPIRNCTEVPVACSHSTDSLSLTDTQPNIPVTETNSEKDMDVSVSKDEQLNKTGQKSRPTGLPQYVLHTVISNDLPDFQNAHSRDSAQNDRYGFNAPATERSRRSPRVFSRKGTSQIHTTQRDQSNKLSKNKCFGGDRTLDSAASPPFIQESGTATSLPSPNQGCHQKTGSNEESSNTIKNSHWCFESTANQKSQPSREPALLDLEQSLSTHSTNDSKLAPGHSISRAPLHVASDAPQESFLDARLVPSTTVFSRSLSDQDPGQEQREEKDKATKSQDNQLAVNSTDNQESHDSPALPHDAVHCHPYSPFKNGRGKGRVRRRVSCIEKLTKTERAAAPTREGSGCAEDQRSIKDPELSTVYCTLPRKPASFLIHSRQQESKGTVASVRNGPLPFQIKNKAEVPTGKSTSDKPSSPESVSDAANAVSGTPKATKKMTDMKAIRSASVRKGPLPFLIKRAISCPSGEPCSLAESDDRQKSSVLGMDASPVIPRPGGRIFNSLEGEPSFRESAFSEKELAQEHTGKDRELRAPRMGLFNPSKKTPERLCATGSGKESGRALHKFKTTSMFSVSGDEENVNCLEVVSIYYTLPRKPSKKFCSLLQQYTQGTDSLRDAFQGETEALPNALEIDELNCPAQVQSGIPPPQDPKMQVDSAPCCLSHSPESKDVSQLPDRETSKSTLEEMTSVGPDVSLHREEPTTKEISPSNVSKTAIDDSLSREKREKELLRQILRAPLLHQEKGAGKEHTKSHQQPSKGGNSGPSGLPSRSEDNDENSQTRRDSGTCAGGMASGNGQYPWRDHMAAVVGDRSSRSQPRETSGTTGSDCQNPTDKMLSDSESQAFALTPALCKLQLAEEAQPGGAGLQSEASQAGSQETNTAEMRKVEDEEHMLTRDQTLLPRGNNKNKTNTDETKDRYSGKHRLAAISKASKRIPAKDLSPRKHVATIFSQSESESGFRRLSLYRPEDNPLSPEPTVKATESTDESSQMNVDKSETLLQETTVSSPGPPGQPCHQKSASILQPHLNGSPGVLETPPKSEGSKTQISGELGAPAQLTLTSPLEKGAGHQQRLSPPFPLEPTQKSTINSHCQLRHRSAPSPESEPEPHLYRSKSLKNFNVQSDLLCASHPPKARGRHFSENTSIDNALSQLSLEDGSFPNSGYNRRFKSSSELPASYESESWTSYSNRTRGPKSTSSISRPIDYGIFGKEQQLAFLENVKRSLTQGRLWKPSFLKNPGFLKDDVLNASNLSQSELVNSPAGQAPEDGVFPSEPLNIYKDDPVEPLVSDWDTDTTTDDEYYLDEKDKESEL sytl4_mouse Synaptotagmin-like protein 4 Sytl4 Slp4 Exophilin-2 Granuphilin protein protein mouse Mus musculus Mouse MSEILDLSFLSEMERDLILGVLQRDEELRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQEGLGRLIPKSSTCVGCNHLVCRECRVLESNGSWRCKVCSKEIELKKATGDWFYDQKVNRFDYRTGSEIIRMSLRQKPAVNKRETAGQSLLQQTQMGDIWPGRRIIQEQQQREQSVLFEVPKTRSGKSALEAESESLDSYTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKEIPPGNQNAVCGDEGDMVFKKNTKKVLRPSEYTKSVIDLRPEDVAQESGILGDRSKSVPGLSVDMEEEEEEEEDIDHLVKLHRQKLARGSMQSGSSMSTLGSIMSIYSEAGDFGNISVTGKIAFSLKFEQKTQTLVIHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETFRYEISESLLAQRTLQFSVWHHGRFGRNTFLGEAEVHMDSWKLDKKLDHCLPLHGKISTESSPGLPAHKGELVVSLKYIPASKLPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKSGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLSPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMVKQKLGV rp3a_mouse Rabphilin-3A Rph3a Exophilin-1 protein protein mouse Mus musculus Mouse MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRPPGQKPGPDLTSAPGRGSHGPPTRRASEARMSTAARDSEGWDHAHGGGTGDTSRSPAGLRRANSVQAARPAPAPVPSPAPPQPVQPGPPGGSRATPGPGRFPEQSTEAPPSDPGYPGAVAPAREERTGPAGGFQAAPHTAAPYSQAAPARQPPPAEEEEEEANSYDSDEATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD rab3a_mouse Ras-related protein Rab-3A Rab3a protein protein mouse Mus musculus Mouse MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQAPPHQDCAC rab8a_mouse Ras-related protein Rab-8A Rab8a Mel Rab8 Oncogene c-mel protein protein mouse Mus musculus Mouse MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITVEQQKRTSFFRCSLL sytl1-rab27a-1 Interaction of the SHD of the Slp family and Slac2 with Rab proteins 141918 N/A 141919 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) N/A 141920 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association false false false Q9ERI2 was FLAG-tagged at the N-terminus. Q99N80 was T7-tagged at the N-terminus. sytl2-rab27a-1 Interaction of the SHD of the Slp family and Slac2 wtih Rab proteins 141918 N/A 141919 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) N/A 141921 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association false false false Q9ERI2 was FLAG-tagged at the N-terminus. Q99N50 was T7-tagged at the N-terminus. sytl3-rab27a-1 Interaction of the SHD of the Slp family and Slac2 with Rab proteins 141918 N/A 141919 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) N/A 141922 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association false false false Q9ERI2 was FLAG-tagged at the N-terminus. Q99N48 was T7-tagged at the N-terminus. mlph-rab27a-1 Interaction of the SHD of the Slp family and Slac2 with Rab proteins 141918 N/A 141919 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) N/A 141923 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association false false false Q9ERI2 was FLAG-tagged at the N-terminus. Q91V27 was T7-tagged at the N-terminus. slac2b-rab27a-1 Interaction of the SHD of the Slp family and Slac2 with Rab proteins 141918 N/A 141919 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) N/A 141924 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association false false false Q9ERI2 was FLAG-tagged at the N-terminus. Q812E3 was T7-tagged at the N-terminus. sytl4-rab27a-1 Interaction of the SHD of the Slp family and Slac2 with Rab proteins 141918 N/A 141919 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) N/A 141925 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association false false false Q9ERI2 was FLAG-tagged at the N-terminus. Q9R0Q1 was T7-tagged at the N-terminus. rph3a-rab27a-1 Interaction of rabphilin-3 with Rab27a 141918 N/A 141919 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) N/A 141926 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association false false false Q9ERI2 was FLAG-tagged at the N-terminus. P47708 was T7-tagged at the N-terminus. sytl4-rab3a-1 Interaction of SYTL-4 with Rab3a 141918 N/A 141925 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) N/A 141927 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) physical association physical association false false false P05713 was FLAG-tagged at the N-terminus. Q9R0Q1 was T7-tagged at the N-terminus. sytl4-rab8a-1 Interaction of Styl4 with rab8a-1 detected by co-immunoprecipitation 141918 N/A 141928 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) N/A 141925 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association false false false P55258 was FLAG-tagged at the N-terminus. Q9R0Q1 was T7-tagged at the N-terminus. rph3a-rab3a-1 interaction of rabphilin-3 with rab8a detected by co-immunoprecipitation 141918 N/A 141926 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) N/A 141927 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) physical association physical association false false false P47708 was T7-tagged at the N-terminus. P05713 was FLAG-tagged at the N-terminus. rph3a-rab8a-1 Interaction of rabphilin-3 with rab8a detected by co-immunoprecipitation 141918 N/A 141926 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) N/A 141928 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) physical association physical association false false false P55258 was FLAG-tagged at the N-terminus. P47708 was T7-tagged at the N-terminus.