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    <entry>
        <source releaseDate="2006-09-22+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
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                </xref>
            </bibref>
            <xref>
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                <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="511482">
                <names>
                    <shortLabel>frazee-1998-1</shortLabel>
                    <fullName>The axial tyrosinate Fe3+ ligand in protocatechuate 3,4-dioxygenase influences substrate binding and product release: evidence for new reaction cycle intermediates.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="9485360" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
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                <xref>
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                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Frazee RW., Orville AM., Dolbeare KB., Yu H., Ohlendorf DH., Lipscomb JD.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
                    <attribute name="journal" nameAc="MI:0885">Biochemistry (0006-2960)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">1998</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="511483">
                <names>
                    <shortLabel>pcxa_psepu</shortLabel>
                    <fullName>Protocatechuate 3,4-dioxygenase alpha chain</fullName>
                    <alias typeAc="MI:0301" type="gene name">pcaG</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">3,4-PCD</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P00436" version="SP_64" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MI1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3T63"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012786"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCF"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YKP"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCA"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MV4"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCG"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YKK"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WHP"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCN"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LXV"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WHS"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MFL"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YKN"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MV6"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2PCD"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCD"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCC"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCI"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_003251601.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YKM"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCM"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WHR"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LKT"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCL"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WHQ"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="303">
                    <names>
                        <shortLabel>psepu</shortLabel>
                        <fullName>Pseudomonas putida</fullName>
                        <alias typeAc="MI:1041" type="synonym">Arthrobacter siderocapsulatus</alias>
                    </names>
                </organism>
                <sequence>MPIELLPETPSQTAGPYVHIGLALEAAGNPTRDQEIWNRLAKPDAPGEHILLLGQVYDGNGHLVRDSFLEVWQADANGEYQDAYNLENAFNSFGRTATTFDAGEWTLHTVKPGVVNNAAGVPMAPHINISLFARGINIHLHTRLYFDDEAQANAKCPVLNLIEQPQRRETLIAKRCEVDGKTAYRFDIRIQGEGETVFFDF</sequence>
            </interactor>
            <interactor id="511484">
                <names>
                    <shortLabel>pcxb_psepu</shortLabel>
                    <fullName>Protocatechuate 3,4-dioxygenase beta chain</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">3,4-PCD</alias>
                    <alias typeAc="MI:0301" type="gene name">pcaH</alias>
                </names>
                <xref>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MI1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3T63"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCA"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MV4"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019619" secondary="3,4-dihydroxybenzoate catabolic process" version="SP_123"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MI5"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018578" secondary="protocatechuate 3,4-dioxygenase activity" version="SP_123"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCB"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LXV"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCJ"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3T67"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WHS"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MFL"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YKN"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MV6"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2PCD"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCD"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YKM"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YKL"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042952" secondary="beta-ketoadipate pathway" version="SP_123"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024756"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCH"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCL"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WHQ"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="303">
                    <names>
                        <shortLabel>psepu</shortLabel>
                        <fullName>Pseudomonas putida</fullName>
                        <alias typeAc="MI:1041" type="synonym">Arthrobacter siderocapsulatus</alias>
                    </names>
                </organism>
                <sequence>MPAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFNNGGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFENC</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="511485">
                <names>
                    <shortLabel>pcag-pcah-1</shortLabel>
                    <fullName>Protocatechuate 3,4-dioxygenase y447h mutant</fullName>
                </names>
                <xref>
                    <primaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCD" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1026834" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>511482</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="511486">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026838" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>511483</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="511487">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026839" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="2"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="201"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="294">
                                <names>
                                    <shortLabel>psefl</shortLabel>
                                    <fullName>Pseudomonas fluorescens</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 6.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="511488">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026835" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>511484</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="511489">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1026836" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="2"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="239"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="294">
                                <names>
                                    <shortLabel>psefl</shortLabel>
                                    <fullName>Pseudomonas fluorescens</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 6.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="assembly">24meric, multimeric</attribute>
                    <attribute name="3d-r-factors" nameAc="MI:0631">working 82.00%</attribute>
                    <attribute name="3d-resolution" nameAc="MI:0632">2.1A</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
