<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2006-09-22+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="19850723" refType="method reference" refTypeAc="MI:0357"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="515481">
                <names>
                    <shortLabel>hirano-2005-1</shortLabel>
                    <fullName>Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="15590654" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041309" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Hirano Y., Yoshinaga S., Takeya R., Suzuki NN., Horiuchi M., Kohjima M., Sumimoto H., Inagaki F.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
                    <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2005</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="515482">
                <names>
                    <shortLabel>kpci_human</shortLabel>
                    <fullName>Protein kinase C iota type</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">nPKC-iota</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Atypical protein kinase C-lambda/iota</alias>
                    <alias typeAc="MI:0301" type="gene name">PRKCI</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DXS1179E</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P41743" version="SP_88" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_228"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P41743" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LI1" version="SP_228"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8WW06" version="SP_88" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007010" secondary="cytoskeleton organization" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043524" secondary="negative regulation of neuron apoptotic process" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045197" secondary="establishment or maintenance of epithelial cell apical/basal polarity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000353" secondary="positive regulation of endothelial cell apoptotic process" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0099072" secondary="regulation of postsynaptic membrane neurotransmitter receptor levels" version="SP_228"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002731.4"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035089" secondary="establishment of apical/basal cell polarity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005543" secondary="phospholipid binding" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004698" secondary="calcium-dependent protein kinase C activity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031252" secondary="cell leading edge" version="SP_228"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-209543" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1WMH" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3A8X" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048194" secondary="Golgi vesicle budding" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045747" secondary="positive regulation of Notch signaling pathway" version="SP_228"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-31311N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070555" secondary="response to interleukin-1" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010976" secondary="positive regulation of neuron projection development" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106311" secondary="protein threonine kinase activity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004674" secondary="protein serine/threonine kinase activity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004697" secondary="protein kinase C activity" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008271" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035556" secondary="intracellular signal transduction" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_228"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000295797" version="SP_228" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007015" secondary="actin filament organization" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005923" secondary="bicellular tight junction" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034351" secondary="negative regulation of glial cell apoptotic process" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020454" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ZH8" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ILZ" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060252" secondary="positive regulation of glial cell proliferation" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005768" secondary="endosome" version="SP_228"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-420029" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000270" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR034877" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004672" secondary="protein kinase activity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098685" secondary="Schaffer collateral - CA1 synapse" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000961" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006612" secondary="protein targeting to membrane" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032869" secondary="cellular response to insulin stimulus" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046326" secondary="positive regulation of glucose import" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012233" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LIH" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015630" secondary="microtubule cytoskeleton" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002219" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018105" secondary="peptidyl-serine phosphorylation" version="SP_228"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000163558" version="SP_228" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016192" secondary="vesicle-mediated transport" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045216" secondary="cell-cell junction organization" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045171" secondary="intercellular bridge" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106310" secondary="protein serine kinase activity" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3A8W" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903078" secondary="positive regulation of protein localization to plasma membrane" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" secondary="cell migration" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061024" secondary="membrane organization" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046903" secondary="secretion" version="SP_228"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1912408" version="SP_228"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DNQ4" version="SP_124" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1ZRZ" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042462" secondary="eye photoreceptor cell development" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR034661" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098978" secondary="glutamatergic synapse" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000139" secondary="Golgi membrane" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043220" secondary="Schmidt-Lanterman incisure" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LI9" version="SP_228"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-286199" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000295797" version="SP_228" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017892" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1VD2" version="SP_228"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MPTQRDSSTMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSFDNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPQEPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV</sequence>
            </interactor>
            <interactor id="515483">
                <names>
                    <shortLabel>par6a_human</shortLabel>
                    <fullName>Partitioning defective 6 homolog alpha</fullName>
                    <alias typeAc="MI:0301" type="gene name">PARD6A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PAR6A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PAR6C</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Tax interaction protein 40</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NPB6" version="SP_59" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q9NPB6" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005813" secondary="centrosome" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007098" secondary="centrosome cycle" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" secondary="transcription factor binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904781" secondary="positive regulation of protein localization to centrosome" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000219255" version="SP_185" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005080" secondary="protein kinase C binding" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000219255" version="SP_185" refType="transcript"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013149" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060341" secondary="regulation of cellular localization" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001933" secondary="negative regulation of protein phosphorylation" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001726" secondary="ruffle" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR034872" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036034" version="SP_185"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NPJ7" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_058644.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013148" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR034868" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-420029" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000102981" version="SP_185" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030742" secondary="GTP-dependent protein binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016032" secondary="viral process" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1WMH" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050714" secondary="positive regulation of protein secretion" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" secondary="cell division" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173791" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005923" secondary="bicellular tight junction" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045217" secondary="cell-cell junction maintenance" version="SP_185"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O14911" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005938" secondary="cell cortex" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4608870" version="SP_185"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001032358.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_185"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-31312N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007163" secondary="establishment or maintenance of cell polarity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031267" secondary="small GTPase binding" version="SP_185"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-81876" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001478" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000270" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034451" secondary="centriolar satellite" version="SP_185"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MARPQRTPARSPDSIVEVKSKFDAEFRRFALPRASVSGFQEFSRLLRAVHQIPGLDVLLGYTDAHGDLLPLTNDDSLHRALASGPPPLRLLVQKRAEADSSGLAFASNSLQRRKKGLLLRPVAPLRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQRNNVVRGASGRLTGPPSAGPGPAEPDSDDDSSDLVIENRQPPSSNGLSQGPPCWDLHPGCRHPGTRSSLPSLDDQEQASSGWGSRIRGDGSGFSL</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="515484">
                <names>
                    <shortLabel>pard6a-prkci-3</shortLabel>
                    <fullName>Crystal structure of a pb1 domain complex of protein kinase
   c iota and par6 alpha</fullName>
                </names>
                <xref>
                    <primaryRef db="rcsb pdb" dbAc="MI:0460" id="1WMH" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1041315" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>515481</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="515485">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041319" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>515482</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="515486">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041320" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="25"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="108"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                    <participant id="515487">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041316" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>515483</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="515488">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041317" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="14"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="95"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="assembly">tetrameric, multimeric</attribute>
                    <attribute name="3d-r-factors" nameAc="MI:0631">working 78.400%, free 77.600%</attribute>
                    <attribute name="3d-resolution" nameAc="MI:0632">1.5A</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
