<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2016-01-13Z">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="19850723" refType="method reference" refTypeAc="MI:0357"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1876445">
                <names>
                    <shortLabel>radhakrishnan-2015-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="25648899" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-11362082" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-24712" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-mimcd_3</shortLabel>
                            <fullName>Mus musculus mIMDC-3 inner medullary collecting duct cells</fullName>
                        </names>
                        <cellType>
                            <names>
                                <shortLabel>mimcd_3</shortLabel>
                                <fullName>mIMCD-3 (murine inner medullary collecting duct cells)</fullName>
                            </names>
                            <xref>
                                <primaryRef db="mint" dbAc="MI:0471" id="MINT-6663897" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1557398" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </cellType>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>ch-ip</shortLabel>
                        <fullName>chromatin immunoprecipitation assay</fullName>
                        <alias typeAc="MI:1041" type="synonym">ch-ip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0402" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-705656" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="12054902" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>q-pcr</shortLabel>
                        <fullName>quantitative pcr</fullName>
                        <alias typeAc="MI:1041" type="synonym">q-pcr</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1195" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6350023" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="12958470" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Radhakrishnan VM., Kojs P., Ramalingam R., Midura-Kiela MT., Angeli P., Kiela PR., Ghishan FK.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">IBD - Inflammatory bowel disease</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">fghishan@peds.arizona.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">The Journal of biological chemistry</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2015</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1876446">
                <names>
                    <shortLabel>slc8a1_mouse_gene</shortLabel>
                    <alias typeAc="MI:0301" type="gene name">Slc8a1</alias>
                </names>
                <xref>
                    <primaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000054640" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-11362093" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001106269.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="G3X9J1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_035536.2"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006524002.1"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>gene</shortLabel>
                        <fullName>gene</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0250" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000704" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-706030" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
            </interactor>
            <interactor id="1876447">
                <names>
                    <shortLabel>stat1_mouse</shortLabel>
                    <fullName>Signal transducer and activator of transcription 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Stat1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P42225" version="SP_67" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1169408"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008015" secondary="blood circulation" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013801" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" secondary="activation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8854691"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043124" secondary="negative regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" secondary="sequence-specific DNA binding" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-186763"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036535" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071407" secondary="cellular response to organic cyclic compound" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003340" secondary="negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002230" secondary="positive regulation of defense response to virus by host" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060337" secondary="type I interferon signaling pathway" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031730" secondary="CCR5 chemokine receptor binding" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-909733"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072308" secondary="negative regulation of metanephric nephron tubule epithelial cell differentiation" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001937" secondary="negative regulation of endothelial cell proliferation" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1433557"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008967" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032727" secondary="positive regulation of interferon-alpha production" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030424" secondary="axon" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034240" secondary="negative regulation of macrophage fusion" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" secondary="DNA-binding transcription factor activity, RNA polymerase II-specific" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034340" secondary="response to type I interferon" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001217" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051770" secondary="positive regulation of nitric-oxide synthase biosynthetic process" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043434" secondary="response to peptide hormone" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012345" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016922" secondary="nuclear receptor binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007259" secondary="receptor signaling pathway via JAK-STAT" version="SP_177"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-647118" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072136" secondary="metanephric mesenchymal cell proliferation involved in metanephros development" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033209" secondary="tumor necrosis factor-mediated signaling pathway" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035859" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051721" secondary="protein phosphatase 2A binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051591" secondary="response to cAMP" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072162" secondary="metanephric mesenchymal cell differentiation" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042127" secondary="regulation of cell population proliferation" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043330" secondary="response to exogenous dsRNA" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061326" secondary="renal tubule development" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8985947"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005164" secondary="tumor necrosis factor receptor binding" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015988" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071345" secondary="cellular response to cytokine stimulus" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016525" secondary="negative regulation of angiogenesis" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035458" secondary="cellular response to interferon-beta" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032869" secondary="cellular response to insulin stimulus" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-877300"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042393" secondary="histone binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006351" secondary="transcription, DNA-templated" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000980" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010742" secondary="macrophage derived foam cell differentiation" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071346" secondary="cellular response to interferon-gamma" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013799" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036860" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003690" secondary="double-stranded DNA binding" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9020958"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-912694"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022752" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019221" secondary="cytokine-mediated signaling pathway" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" secondary="DNA-binding transcription factor binding" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9020956"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032496" secondary="response to lipopolysaccharide" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034097" secondary="response to cytokine" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048661" secondary="positive regulation of smooth muscle cell proliferation" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070106" secondary="interleukin-27-mediated signaling pathway" version="SP_177"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-38739N"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013800" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000979" secondary="RNA polymerase II core promoter sequence-specific DNA binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035456" secondary="response to interferon-beta" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002053" secondary="positive regulation of mesenchymal cell proliferation" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035035" secondary="histone acetyltransferase binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990841" secondary="promoter-specific chromatin binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" secondary="DNA-binding transcription factor activity" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044389" secondary="ubiquitin-like protein ligase binding" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060333" secondary="interferon-gamma-mediated signaling pathway" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031663" secondary="lipopolysaccharide-mediated signaling pathway" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1059683"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-877312"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6785807"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006952" secondary="defense response" version="SP_177"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR038295" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" secondary="cellular response to lipopolysaccharide" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009612" secondary="response to mechanical stimulus" version="SP_177"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8984722"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045648" secondary="positive regulation of erythrocyte differentiation" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007584" secondary="response to nutrient" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046725" secondary="negative regulation by virus of viral protein levels in host cell" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030425" secondary="dendrite" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009617" secondary="response to bacterium" version="SP_177"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051607" secondary="defense response to virus" version="SP_177"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MSQWFELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAAYDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPVQMSMIIYNCLKEERKILENAQRFNQAQEGNIQNTVMLDKQKELDSKVRNVKDQVMCIEQEIKTLEELQDEYDFKCKTSQNREGEANGVAKSDQKQEQLLLHKMFLMLDNKRKEIIHKIRELLNSIELTQNTLINDELVEWKRRQQSACIGGPPNACLDQLQTWFTIVAETLQQIRQQLKKLEELEQKFTYEPDPITKNKQVLSDRTFLLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKSRLLVKLQESNLLTKVKCHFDKDVNEKNTVKGFRKFNILGTHTKVMNMEESTNGSLAAELRHLQLKEQKNAGNRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVTEPRNLSFFLNPPCAWWSQLSEVLSWQFSSVTKRGLNADQLSMLGEKLLGPNAGPDGLIPWTRFCKENINDKNFSFWPWIDTILELIKNDLLCLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDDPKRTGYIKTELISVSEVHPSRLQTTDNLLPMSPEEFDEMSRIVGPEFDSMMSTV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-24712-1" id="1876448">
                <names>
                    <shortLabel>stat1-slc8a1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-11362090" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-24712-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1876445</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1876449">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-11362099" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1876446</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1876450">
                                <names>
                                    <shortLabel>promoter_region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-11362101" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                    <participant id="1876451">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-11362092" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1876447</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">5D</attribute>
                    <attribute name="agonist" nameAc="MI:0625">IFN-gamma (P01580 )</attribute>
                    <attribute name="causality statement">P01580 increases the binding of P42225 to ENSMUSG00000054640</attribute>
                    <attribute name="causality statement">P01580  decreases the expression at RNA level of ENSMUSG00000054640</attribute>
                    <attribute name="causality statement">P01580  decreases the expression at protein level of ENSMUSG00000054640</attribute>
                    <attribute name="causality statement">P01580  increased the expression at protein level of P42225</attribute>
                    <attribute name="causality statement">P42225  is required  for the P01580  induced decrease in expression at RNA level of  ENSMUSG00000054640</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
