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    <entry>
        <source releaseDate="2015-08-25+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
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                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
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            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1854576">
                <names>
                    <shortLabel>ouyang-2010-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="20467422" refType="primary-reference" refTypeAc="MI:0358"/>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-t-cell</shortLabel>
                            <fullName>Mouse T cell</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>t-cell</shortLabel>
                                <fullName>Peripheral blood T-lymphocytes</fullName>
                            </names>
                            <xref>
                                <primaryRef db="mint" dbAc="MI:0471" id="MINT-1339457" refType="identity" refTypeAc="MI:0356"/>
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                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>ch-ip</shortLabel>
                        <fullName>chromatin immunoprecipitation assay</fullName>
                        <alias typeAc="MI:1041" type="synonym">ch-ip</alias>
                    </names>
                    <xref>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>q-pcr</shortLabel>
                        <fullName>quantitative pcr</fullName>
                        <alias typeAc="MI:1041" type="synonym">q-pcr</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1195" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6350023" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="12958470" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Ouyang W., Beckett O., Ma Q., Paik JH., DePinho RA., Li MO.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">IBD - Inflammatory bowel disease</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">TReg cells:Foxp3+CD4+</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">lim@mskcc.org</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature immunology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2010</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1854577">
                <names>
                    <shortLabel>foxo1_mouse</shortLabel>
                    <fullName>Forkhead box protein O1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Foxo1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Fkhr</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Foxo1a</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Forkhead box protein O1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Forkhead in rhabdomyosarcoma</alias>
                </names>
                <xref>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010508" secondary="positive regulation of autophagy" version="SP_188"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_062713.2"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-198693" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-211163" version="SP_188"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030456" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090090" secondary="negative regulation of canonical Wnt signaling pathway" version="SP_188"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000044167" version="SP_188" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006111" secondary="regulation of gluconeogenesis" version="SP_188"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032067" version="SP_188"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097150" secondary="neuronal stem cell population maintenance" version="SP_188"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032068" version="SP_188"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001568" secondary="blood vessel development" version="SP_188"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045722" secondary="positive regulation of gluconeogenesis" version="SP_188"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_188"/>
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                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1371343" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008286" secondary="insulin receptor signaling pathway" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_188"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9617629" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034599" secondary="cellular response to oxidative stress" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045599" secondary="negative regulation of fat cell differentiation" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006914" secondary="autophagy" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006974" secondary="cellular response to DNA damage stimulus" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051721" secondary="protein phosphatase 2A binding" version="SP_188"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036388" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902617" secondary="response to fluoride" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008013" secondary="beta-catenin binding" version="SP_188"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042593" secondary="glucose homeostasis" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042127" secondary="regulation of cell population proliferation" version="SP_188"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070542" secondary="response to fatty acid" version="SP_188"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903243" secondary="negative regulation of cardiac muscle hypertrophy in response to stress" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071549" secondary="cellular response to dexamethasone stimulus" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_188"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032873" secondary="negative regulation of stress-activated MAPK cascade" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" secondary="sequence-specific DNA binding" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071732" secondary="cellular response to nitric oxide" version="SP_188"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q9R1E0" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030154" secondary="cell differentiation" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009267" secondary="cellular response to starvation" version="SP_188"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAEAPQVVETDPDFEPLPRQRSCTWPLPRPEFNQSNSTTSSPAPSGGAAANPDAAASLASASAVSTDFMSNLSLLEESEDFARAPGCVAVAAAAAASRGLCGDFQGPEAGCVHPAPPQPPPTGPLSQPPPVPPSAAAAAGPLAGQPRKTSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRGRAAKKKASLQSGQEGPGDSPGSQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIMTEQDDLGDGDVHSLVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTVSTQSSPGSMMQQTPCYSFAPPNTSLNSPSPNYSKYTYGQSSMSPLPQMPMQTLQDSKSSYGGLNQYNCAPGLLKELLTSDSPPHNDIMSPVDPGVAQPNSRVLGQNVMMGPNSVMPAYGSQASHNKMMNPSSHTHPGHAQQTASVNGRTLPHVVNTMPHTSAMNRLTPVKTPLQVPLSHPMQMSALGSYSSVSSCNGYGRMGVLHQEKLPSDLDGMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLPNQSFPHSVKTTTHSWVSG</sequence>
            </interactor>
            <interactor id="1854578">
                <names>
                    <shortLabel>foxp3_mouse_gene</shortLabel>
                    <fullName>Forkhead box protein P3</fullName>
                    <alias typeAc="MI:0301" type="gene name">Foxp3</alias>
                </names>
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                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10899641" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_473380.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001186276.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001186277.1"/>
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                <interactorType>
                    <names>
                        <shortLabel>gene</shortLabel>
                        <fullName>gene</fullName>
                    </names>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
            </interactor>
            <interactor id="1854579">
                <names>
                    <shortLabel>foxo3_mouse</shortLabel>
                    <fullName>Forkhead box protein O3</fullName>
                    <alias typeAc="MI:0301" type="gene name">Foxo3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Fkhr2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Foxo3a</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901300" secondary="positive regulation of hydrogen peroxide-mediated programmed cell death" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" secondary="DNA-binding transcription factor activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001547" secondary="antral ovarian follicle growth" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001542" secondary="ovulation from ovarian follicle" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090090" secondary="negative regulation of canonical Wnt signaling pathway" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9617828" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042594" secondary="response to starvation" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001221" secondary="transcription coregulator binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990090" secondary="cellular response to nerve growth factor stimulus" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006390" secondary="mitochondrial transcription" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097192" secondary="extrinsic apoptotic signaling pathway in absence of ligand" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000353" secondary="positive regulation of endothelial cell apoptotic process" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032067" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000050683" version="SP_185" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000135380" version="SP_185" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071548" secondary="response to dexamethasone" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001544" secondary="initiation of primordial ovarian follicle growth" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032068" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034246" secondary="mitochondrial transcription factor activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904646" secondary="cellular response to amyloid-beta" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036390" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071456" secondary="cellular response to hypoxia" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097150" secondary="neuronal stem cell population maintenance" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_185"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9614399" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" secondary="DNA-binding transcription activator activity, RNA polymerase II-specific" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5687128" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9634638" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9617629" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034599" secondary="cellular response to oxidative stress" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043525" secondary="positive regulation of neuron apoptotic process" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000175881" version="SP_185" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008013" secondary="beta-catenin binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030330" secondary="DNA damage response, signal transduction by p53 class mediator" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014737" secondary="positive regulation of muscle atrophy" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036388" version="SP_185"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q05CZ4" version="SP_103" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902895" secondary="positive regulation of pri-miRNA transcription by RNA polymerase II" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033209" secondary="tumor necrosis factor-mediated signaling pathway" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001766" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048854" secondary="brain morphogenesis" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000105502" version="SP_185" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071386" secondary="cellular response to corticosterone stimulus" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990785" secondary="response to water-immersion restraint stress" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042593" secondary="glucose homeostasis" version="SP_185"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3Z6Y6" version="SP_103" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031490" secondary="chromatin DNA binding" version="SP_185"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6127038" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042149" secondary="cellular response to glucose starvation" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070542" secondary="response to fatty acid" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1181150" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000048756" version="SP_185" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001556" secondary="oocyte maturation" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045648" secondary="positive regulation of erythrocyte differentiation" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006417" secondary="regulation of translation" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001227" secondary="DNA-binding transcription repressor activity, RNA polymerase II-specific" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071333" secondary="cellular response to glucose stimulus" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000377" secondary="regulation of reactive oxygen species metabolic process" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" secondary="regulation of transcription, DNA-templated" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9607240" version="SP_185"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006512869.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000056974" version="SP_185" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005759" secondary="mitochondrial matrix" version="SP_185"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_062714.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" secondary="DNA-binding transcription factor activity, RNA polymerase II-specific" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007568" secondary="aging" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" secondary="sequence-specific DNA binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" secondary="sequence-specific double-stranded DNA binding" version="SP_185"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAEAPASPVPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEDDDEDDEDGGGRASSAMVIGGGVSSTLGSGLLLEDSAMLLAPGGQDLGSGPASAAGALSGGTPTQLQPQQPLPQPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQAAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPILASTELDDVQDDDGPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLAENLMDDLLDNIALPPSQPSPPGGLMQRGSSFPYTAKSSGLGSPTGSFNSTVFGPSSLNSLRQSPMQTIQENRPATFSSVSHYGNQTLQDLLASDSLSHSDVMMTQSDPLMSQASTAVSAQNARRNVMLRNDPMMSFAAQPTQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSDSSSLGSAKHQQQSPASQSMQTLSDSLSGSSLYSASANLPVMGHDKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-24363-1" id="1854580">
                <names>
                    <shortLabel>foxo1-foxp3-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904466" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-24363-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1854576</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1854581">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904482" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1854577</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1854582">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904468" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1854578</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1854583">
                                <names>
                                    <shortLabel>cns1_enhancer_region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904469" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                            <feature id="1854584">
                                <names>
                                    <shortLabel>cns3_enhancer_region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904483" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">8C</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-24363-3" id="1854585">
                <names>
                    <shortLabel>foxo1-foxp3-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904485" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-24363-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1854576</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1854586">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904488" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1854578</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1854587">
                                <names>
                                    <shortLabel>cns1_enhancer_region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904489" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                            <feature id="1854588">
                                <names>
                                    <shortLabel>cns3_enhancer_region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904491" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                    <participant id="1854589">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10904487" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1854579</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">8D</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
