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    <entry>
        <source releaseDate="2012-08-20+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10" refType="identity" refTypeAc="MI:0356"/>
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                <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1307383">
                <names>
                    <shortLabel>bywater-2012-1</shortLabel>
                    <fullName>Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="22789538" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6248389" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-17409" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-lymphoma</shortLabel>
                            <fullName>Mus musculus</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>lymphoma</shortLabel>
                                <fullName>Lymphoma</fullName>
                            </names>
                            <xref>
                                <primaryRef db="intact" dbAc="MI:0469" id="IA:1001" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="brenda" dbAc="MI:0864" id="BTO:0000785" refType="identity" refTypeAc="MI:0356"/>
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                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Bywater M.J., Poortinga G., Sanij E., Hein N., Peck A., Cullinane C., Wall M., Cluse L., Drygin D., Anderes K., Huser N., Proffitt C., Bliesath J., Haddach M., Schwaebe M.K., Ryckman D.M., Rice W.G., Schmitt C., Lowe S.W., Johnstone R.W., Pearson R.B., McArthur G.A., Hannan R.D.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Cancer - Interactions investigated in the context of cancer</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">Eμ-Myc lymphoma cells -MYC and BCL2  are overexpressed in lymphocytes of the B lineage.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">ross.hannan@petermac.org</attribute>
                    <attribute name="journal" nameAc="MI:0885">Cancer Cell (1535-6108)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1307384">
                <names>
                    <shortLabel>rl5_mouse</shortLabel>
                    <fullName>60S ribosomal protein L5</fullName>
                    <alias typeAc="MI:0301" type="gene name">Rpl5</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P47962" version="SP_61" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_058676.1"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P47962" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-975956" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010922" secondary="positive regulation of phosphatase activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003735" secondary="structural constituent of ribosome" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005485" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-975957" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000082223" version="SP_185" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SWA" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022625" secondary="cytosolic large ribosomal subunit" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022626" secondary="cytosolic ribosome" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006364" secondary="rRNA processing" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017101" secondary="aminoacyl-tRNA synthetase multienzyme complex" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042273" secondary="ribosomal large subunit biogenesis" version="SP_185"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000058558" version="SP_185" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000080854" version="SP_185" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048027" secondary="mRNA 5'-UTR binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005783" secondary="endoplasmic reticulum" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071241" secondary="cellular response to inorganic substance" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR025607" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000435" secondary="negative regulation of protein neddylation" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000027" secondary="ribosomal large subunit assembly" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045727" secondary="positive regulation of translation" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905017" secondary="positive regulation of isoleucine-tRNA ligase activity" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000059" secondary="negative regulation of ubiquitin-dependent protein catabolic process" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008097" secondary="5S rRNA binding" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990948" secondary="ubiquitin ligase inhibitor activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006412" secondary="translation" version="SP_185"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904667" secondary="negative regulation of ubiquitin protein ligase activity" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6791226" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901796" secondary="regulation of signal transduction by p53 class mediator" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014069" secondary="postsynaptic density" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003729" secondary="mRNA binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050821" secondary="protein stabilization" version="SP_185"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1799339" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905020" secondary="positive regulation of methionine-tRNA ligase activity" version="SP_185"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVNGGEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES</sequence>
            </interactor>
            <interactor id="1307385">
                <names>
                    <shortLabel>rl11_mouse</shortLabel>
                    <fullName>60S ribosomal protein L11</fullName>
                    <alias typeAc="MI:0301" type="gene name">Rpl11</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9CXW4" version="SP_51" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000435" secondary="negative regulation of protein neddylation" version="SP_162"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022803" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000027" secondary="ribosomal large subunit assembly" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032435" secondary="negative regulation of proteasomal ubiquitin-dependent protein catabolic process" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002181" secondary="cytoplasmic translation" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034504" secondary="protein localization to nucleus" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000059" secondary="negative regulation of ubiquitin-dependent protein catabolic process" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008097" secondary="5S rRNA binding" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043433" secondary="negative regulation of DNA-binding transcription factor activity" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990948" secondary="ubiquitin ligase inhibitor activity" version="SP_162"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-72689" version="SP_162"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6ZWY0" version="SP_51" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032092" secondary="positive regulation of protein binding" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901798" secondary="positive regulation of signal transduction by p53 class mediator" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003723" secondary="RNA binding" version="SP_162"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904667" secondary="negative regulation of ubiquitin protein ligase activity" version="SP_162"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6791226" version="SP_162"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042975" secondary="peroxisome proliferator activated receptor binding" version="SP_162"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022625" secondary="cytosolic large ribosomal subunit" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006364" secondary="rRNA processing" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006605" secondary="protein targeting" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042273" secondary="ribosomal large subunit biogenesis" version="SP_162"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_080195.1"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020929" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_162"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK</sequence>
            </interactor>
            <interactor id="1307386">
                <names>
                    <shortLabel>mdm2_mouse</shortLabel>
                    <fullName>E3 ubiquitin-protein ligase Mdm2</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">p53-binding protein Mdm2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Oncoprotein Mdm2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Double minute 2 protein</alias>
                    <alias typeAc="MI:0301" type="gene name">Mdm2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RING-type E3 ubiquitin transferase Mdm2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P23804" version="SP_82" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045787" secondary="positive regulation of cell cycle" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001568" secondary="blood vessel development" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019789" secondary="SUMO transferase activity" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001974" secondary="blood vessel remodeling" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007507" secondary="heart development" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902254" secondary="negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator" version="SP_215"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5689880" version="SP_215"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000020408" version="SP_215" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061663" secondary="NEDD8 ligase activity" version="SP_215"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001876" version="SP_215"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001841" version="SP_215"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-3232142" version="SP_215"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q61040" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043021" secondary="ribonucleoprotein complex binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045472" secondary="response to ether" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071363" secondary="cellular response to growth factor stimulus" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" secondary="protein domain specific binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0065003" secondary="protein-containing complex assembly" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031648" secondary="protein destabilization" version="SP_215"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_034916.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060411" secondary="cardiac septum morphogenesis" version="SP_215"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P23804" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016567" secondary="protein ubiquitination" version="SP_215"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q64330" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071391" secondary="cellular response to estrogen stimulus" version="SP_215"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8941858" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072717" secondary="cellular response to actinomycin D" version="SP_215"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6804756" version="SP_215"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015459" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010468" secondary="regulation of gene expression" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043130" secondary="ubiquitin binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071375" secondary="cellular response to peptide hormone stimulus" version="SP_215"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-641788" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q91XK7" version="SP_120" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034504" secondary="protein localization to nucleus" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061630" secondary="ubiquitin protein ligase activity" version="SP_215"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-399719" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0047485" secondary="protein N-terminus binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010977" secondary="negative regulation of neuron projection development" version="SP_215"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR028340" version="SP_215"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-24196N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071494" secondary="cellular response to UV-C" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990000" secondary="amyloid fibril formation" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009636" secondary="response to toxic substance" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016874" secondary="ligase activity" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032436" secondary="positive regulation of proteasomal ubiquitin-dependent protein catabolic process" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003283" secondary="atrial septum development" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010039" secondary="response to iron ion" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071456" secondary="cellular response to hypoxia" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042975" secondary="peroxisome proliferator activated receptor binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051149" secondary="positive regulation of muscle cell differentiation" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904754" secondary="positive regulation of vascular associated smooth muscle cell migration" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006511" secondary="ubiquitin-dependent protein catabolic process" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" secondary="zinc ion binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004842" secondary="ubiquitin-protein transferase activity" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904404" secondary="response to formaldehyde" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071301" secondary="cellular response to vitamin B1" version="SP_215"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6804760" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048545" secondary="response to steroid hormone" version="SP_215"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-198323" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032026" secondary="response to magnesium ion" version="SP_215"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013083" version="SP_215"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-2559585" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010955" secondary="negative regulation of protein processing" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051865" secondary="protein autoubiquitination" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007089" secondary="traversing start control point of mitotic cell cycle" version="SP_215"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003121" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071480" secondary="cellular response to gamma radiation" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006977" secondary="DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045931" secondary="positive regulation of mitotic cell cycle" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002027" secondary="regulation of heart rate" version="SP_215"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016495" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003281" secondary="ventricular septum development" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901797" secondary="negative regulation of signal transduction by p53 class mediator" version="SP_215"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-24174N"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-69541" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016604" secondary="nuclear body" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042220" secondary="response to cocaine" version="SP_215"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001275515.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042176" secondary="regulation of protein catabolic process" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" secondary="regulation of cell cycle" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045184" secondary="establishment of protein localization" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002039" secondary="p53 binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071312" secondary="cellular response to alkaloid" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_215"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR044080" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051603" secondary="proteolysis involved in cellular protein catabolic process" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097718" secondary="disordered domain specific binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043278" secondary="response to morphine" version="SP_215"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000020408" version="SP_215" refType="transcript"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043154" secondary="negative regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_215"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003170" secondary="heart valve development" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990785" secondary="response to water-immersion restraint stress" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003181" secondary="atrioventricular valve morphogenesis" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008097" secondary="5S rRNA binding" version="SP_215"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000020184" version="SP_215" refType="gene"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036443" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070301" secondary="cellular response to hydrogen peroxide" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046827" secondary="positive regulation of protein export from nucleus" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003203" secondary="endocardial cushion morphogenesis" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033612" secondary="receptor serine/threonine kinase binding" version="SP_215"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-6804757" version="SP_215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_215"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MCNTNMSVSTEGAASTSQIPASEQETLVRPKPLLLKLLKSVGAQNDTYTMKEIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDVFGVPSFSVKEHRKIYAMIYRNLVAVSQQDSGTSLSESRRQPEGGSDLKDPLQAPPEEKPSSSDLISRLSTSSRRRSISETEENTDELPGERHRKRRRSLSFDPSLGLCELREMCSGGSSSSSSSSSESTETPSHQDLDDGVSEHSGDCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRVTVYQTGESDTDSFEGDPEISLADYWKCTSCNEMNPPLPSHCKRCWTLRENWLPDDKGKDKVEISEKAKLENSAQAEEGLDVPDGKKLTENDAKEPCAEEDSEEKAEQTPLSQESDDYSQPSTSSSIVYSSQESVKELKEETQDKDESVESSFSLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-17409-1" id="1307387">
                <names>
                    <shortLabel>mdm2-rpl11-5</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6248397" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-17409-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1307383</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1307388">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6248401" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1307384</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1307389">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6248400" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1307385</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1307390">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6248399" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1307386</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig 4F</attribute>
                    <attribute name="agonist" nameAc="MI:0625">CX-5461 - a Pol1 transcription inhibitor.</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
