IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ eloranta-2002-2 Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Eloranta JJ., Hurst HC. Cancer - Interactions investigated in the context of cancer helen.hurst@cancer.org.uk Human placental cDNA library J. Biol. Chem. (0021-9258) 2002 Only protein-protein interactions imex curation eloranta-2002-1 Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid full dna sequence full identification by DNA sequencing full dna sequence Eloranta JJ., Hurst HC. Cancer - Interactions investigated in the context of cancer helen.hurst@cancer.org.uk Human placental cDNA library J. Biol. Chem. (0021-9258) 2002 Only protein-protein interactions imex curation ap2a_human Transcription factor AP-2-alpha TFAP2 TFAP2A AP2TF Activating enhancer-binding protein 2-alpha AP-2 transcription factor Activator protein 2 protein protein human Homo sapiens Human MLWKLTDNIKYEDCEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPPPYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAVAEFLNRQHSDPNEQVTRKNMLLATKQICKEFTDLLAQDRSPLGNSRPNPILEPGIQSCLTHFNLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNNAKSSDKEEKHRK ubc9_human SUMO-conjugating enzyme UBC9 UBE2I p18 SUMO-protein ligase UBC9 UBCE9 Ubiquitin carrier protein 9 Ubiquitin carrier protein I Ubiquitin-conjugating enzyme E2 I Ubiquitin-protein ligase I RING-type E3 SUMO transferase UBC9 protein protein human Homo sapiens Human MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS ap2b_human Transcription factor AP-2-beta Activating enhancer-binding protein 2-beta TFAP2B protein protein human Homo sapiens Human MHSPPRDQAAIMLWKLVENVKYEDIYEDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHRK ap2c_human Transcription factor AP-2 gamma TFAP2C Activating enhancer-binding protein 2 gamma Transcription factor ERF-1 protein protein human Homo sapiens Human MLWKITDNVKYEEDCEDRHDGSSNGNPRVPHLSSAGQHLYSPAPPLSHTGVAEYQPPPYFPPPYQQLAYSQSADPYSHLGEAYAAAINPLHQPAPTGSQQQAWPGRQSQEGAGLPSHHGRPAGLLPHLSGLEAGAVSARRDAYRRSDLLLPHAHALDAAGLAENLGLHDMPHQMDEVQNVDDQHLLLHDQTVIRKGPISMTKNPLNLPCQKELVGAVMNPTEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAHVTLLTSLVEGEAVHLARDFAYVCEAEFPSKPVAEYLTRPHLGGRNEMAARKNMLLAAQQLCKEFTELLSQDRTPHGTSRLAPVLETNIQNCLSHFSLITHGFGSQAICAAVSALQNYIKEALIVIDKSYMNPGDQSPADSNKTLEKMEKHRK ap2a-ubc9-1 Interaction between human AP2 alpha and UBC9 detected by Y2H 372224 N/A 372226 unspecified role unspecified role bait bait N/A 372227 unspecified role unspecified role prey prey physical association physical association false false false 1 ap2b-ubc9-1 Interaction between human AP2 beta and UBC9 detected by Y2H 372224 N/A 372228 unspecified role unspecified role bait bait N/A 372227 unspecified role unspecified role prey prey physical association physical association false false false 1 ap2g-ubc9-2 Interaction between human AP2 gamma and UBC9 detected by Y2H 372224 N/A 372227 unspecified role unspecified role prey prey N/A 372229 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false 2B ubc9-ap2a-1 Interaction between human UBC9 and APC alpha detected by Y2H 372224 N/A 372227 unspecified role unspecified role bait bait N/A 372226 unspecified role unspecified role prey prey physical association physical association false false false ubc9-ap2b-1 Interaction between human UBC9 and APC beta detected by Y2H 372224 N/A 372227 unspecified role unspecified role bait bait N/A 372228 unspecified role unspecified role prey prey physical association physical association false false false ubc9-ap2g-1 Interaction between human UBC9 and APC gamma detected by Y2H 372224 N/A 372227 unspecified role unspecified role bait bait N/A 372229 unspecified role unspecified role prey prey physical association physical association false false false ap2g-ubc9-1 Interaction between human AP2 gamma and UBC9 detected by Y2H 372225 N/A 372227 unspecified role unspecified role prey prey N/A 372229 unspecified role unspecified role bait bait physical association physical association false false false