IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ lee-1999-1 A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Lee SK., Anzick SL., Choi JE., Bubendorf L., Guan XY., Jung YK., Kallioniemi OP., Kononen J., Trent JM., Azorsa D., Jhun BH., Cheong JH., Lee YC., Meltzer PS., Lee JW. Cancer - Interactions investigated in the context of cancer J. Biol. Chem. (0021-9258) 1999 lee-1999-2 A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo. in vitro In vitro pull down pull down predetermined predetermined participant predetermined Lee SK., Anzick SL., Choi JE., Bubendorf L., Guan XY., Jung YK., Kallioniemi OP., Kononen J., Trent JM., Azorsa D., Jhun BH., Cheong JH., Lee YC., Meltzer PS., Lee JW. Cancer - Interactions investigated in the context of cancer J. Biol. Chem. (0021-9258) 1999 ncoa3_xenla Nuclear receptor coactivator 3 ncoa3 Retinoid X receptor-interacting coactivator xSRC-3 protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MSGLGENSLDPLASETRKRKPSSCDTPGPGLTCSGEKRRREQESKYIEELADLISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKASSNDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLYVVNREGSIVFVSENVTQYLQYKQEDLVNTSVYSILHEEDRKDFLKNLPKSTVNGVPWFSETPRQKSHTFNCRMLVKTSHDHLEDGSNLDARQRYETMQCFALSQPRAMIEEGEDLQSCMICVARRITTAERAFSANPESFITRHDLTGKVVNIDANSLRSSMRPGFEDTIRRCIQRFLFHSEGQPWTYKRHYQEAYVHGLSETPLYRFSLADGTMVTAQTKSKLFRNPVTNDPHGFVSTHFLQREQNGYRPNPNPMAQGIRPQMNPNLPNTMNSMPPQAMQQQNRNYGMGDPNSMAQMQGMRYKSPGNMAPVNQAPGVQQSPYQNNSNYGLNMNSPPHGSPGMNANQPNLMVSPRNRASPKMASNQFSPVPGMNSPMGSSGNAGGGSFSSSSLSALHAISEGVGSSLLSSLSSPGQKVENNSNMNMPQQGKICNQDCKSPSGLYCEQGQVESSVCQSSGREHLGEKDVKENIFEGSESQRSQAESKGHKKLLQLLTCFTEERGQSLMSSSSMDCKDSSNVTSPSGVSSSTSIGVSSTSNLHGSMLQEKHRILHKLLQNGNSPAEVAKITAEATGKDVFQETVSSAPCTEATVKREQLSPKKKENNALLRHLLDKDDWKDPLAKDIKPKVEHMDIKMGSCSSSNVPTSSQDKEVKIKTEPGEEVPGDLDNLDAILGDLAGSDFYSNSMSSRASDLGPKQPVFQDSPTLAMRSPDSMQGSRPPFNRAMSLDSRSSTPPVRNVNSFPMLPKQGMIGSPRMMDGQDNFGVMMGSGPNRSMNQHPGGDWAMQNSAVNRLEPPNVGSVGRPGPDYSSAMTRPAMGGNMPGLLTRSNSIPGSRPVMQQQQHILPMRPNDMAMSMGSNPYGQQAPSNPPGSWPDAIMMNQGRGGAQNRQLGRNSLDDLLCPPSTVEGQTDEIALLDQLHTLLSNTDATGLEEIDRALGIPDLVSQGQALEPQPDSYQPQGSPVMIDQKPPMYGQHYAGQGAAMSAGGFNNMQGQHPPFNTVMGQMNQQQGMHPLQGMHPRANLIRPRNNIPKQLRMQLQQRLQGQQFLNQNRQALEMKVDPMNPGGAGVMRPVMQTPVSQQGFLNAQMVAQKNRELISHQIRQHRMAMMMQQQQGQPQAFSPPPNVTASASMDNPLGGPPMPQAPPQQFSYPPNYGINQQTDPTFGRVSSPPNAMMSSRMAPSQNPHPQTTQMYPSPDMKGWPSGNMARPNSFPQQQYSHQTNPATYNMMHMNGNGNHMGQMNINSLPMSGMPMGPDQKYC o57539-1 Nuclear receptor coactivator 3 ncoa3 Retinoid X receptor-interacting coactivator xSRC-3 protein protein xenla Xenopus laevis (African clawed frog) African clawed frog MSGLGENSLDPLASETRKRKPSSCDTPGPGLTCSGEKRRREQESKYIEELADLISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKASSNDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLYVVNREGSIVFVSENVTQYLQYKQEDLVNTSVYSILHEEDRKDFLKNLPKSTVNGVPWFSETPRQKSHTFNCRMLVKTSHDHLEDGSNLDARQRYETMQCFALSQPRAMIEEGEDLQSCMICVARRITTAERAFSANPESFITRHDLTGKVVNIDANSLRSSMRPGFEDTIRRCIQRFLFHSEGQPWTYKRHYQEAYVHGLSETPLYRFSLADGTMVTAQTKSKLFRNPVTNDPHGFVSTHFLQREQNGYRPNPNPMAQGIRPQMNPNLPNTMNSMPPQAMQQQNRNYGMGDPNSMAQMQGMRYKSPGNMAPVNQAPGVQQSPYQNNSNYGLNMNSPPHGSPGMNANQPNLMVSPRNRASPKMASNQFSPVPGMNSPMGSSGNAGGGSFSSSSLSALHAISEGVGSSLLSSLSSPGQKVENNSNMNMPQQGKICNQDCKSPSGLYCEQGQVESSVCQSSGREHLGEKDVKENIFEGSESQRSQAESKGHKKLLQLLTCFTEERGQSLMSSSSMDCKDSSNVTSPSGVSSSTSIGVSSTSNLHGSMLQEKHRILHKLLQNGNSPAEVAKITAEATGKDVFQETVSSAPCTEATVKREQLSPKKKENNALLRHLLDKDDWKDPLAKDIKPKVEHMDIKMGSCSSSNVPTSSQDKEVKIKTEPGEEVPGDLDNLDAILGDLAGSDFYSNSMSSRASDLGPKQPVFQDSPTLAMRSPDSMQGSRPPFNRAMSLDSRSSTPPVRNVNSFPMLPKQGMIGSPRMMDGQDNFGVMMGSGPNRSMNQHPGGDWAMQNSAVNRLEPPNVGSVGRPGPDYSSAMTRPAMGGNMPGLLTRSNSIPGSRPVMQQQQHILPMRPNDMAMSMGSNPYGQQAPSNPPGSWPDAIMMNQGRGGAQNRQLGRNSLDDLLCPPSTVEGQTDEIALLDQLHTLLSNTDATGLEEIDRALGIPDLVSQGQALEPQPDSYQPQGSPVMIDQKPPMYGQHYAGQGAAMSAGGFNNMQGQHPPFNTVMGQMNQQQGMHPLQGMHPRANLIRPRNNIPKQLRMQLQQRLQGQQFLNQNRQALEMKVDPMNPGGAGVMRPVMQTPVSQQGFLNAQMVAQKNRELISHQIRQHRMAMMMQQQQGQPQAFSPPPNVTASASMDNPLGGPPMPQAPPQQFSYPPNYGINQQTDPTFGRVSSPPNAMMSSRMAPSQNPHPQTTQMYPSPDMKGWPSGNMARPNSFPQQQYSHQTNPATYNMMHMNGNGNHMGQMNINSLPMSGMPMGPDQKYC rxr-asc2 A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo 104204 N/A 104206 unspecified role unspecified role bait bait N/A 104207 unspecified role unspecified role prey prey physical association physical association false false false asc2-rxr A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo 104205 N/A 104206 enzyme enzyme unspecified role unspecified role N/A 104207 enzyme target enzyme target substrate substrate unspecified role unspecified role physical association physical association false false false