IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ griffiths-2011-2 Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathway. rat-h9c2 h9c2 rat myoblasts h9c2 h9c2 rat myoblasts anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Griffiths G.S., Grundl M., Leychenko A., Reiter S., Young-Robbins S.S., Sulzmaier F.J., Caliva M.J., Ramos J.W., Matter M.L. Apoptosis - Interactions involving proteins with a function related to apoptosis matter@hawaii.edu J. Biol. Chem. (0021-9258) 2011 Only protein-protein interactions imex curation griffiths-2011-3 Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathway. human-hcaec human coronary artery endothelial cells hcaec human cardiac artery endothelial cells anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Griffiths G.S., Grundl M., Leychenko A., Reiter S., Young-Robbins S.S., Sulzmaier F.J., Caliva M.J., Ramos J.W., Matter M.L. Apoptosis - Interactions involving proteins with a function related to apoptosis matter@hawaii.edu J. Biol. Chem. (0021-9258) 2011 Only protein-protein interactions imex curation griffiths-2011-1 Bit-1 mediates integrin-dependent cell survival through activation of the NFkappaB pathway. rat-h9c2 h9c2 rat myoblasts h9c2 h9c2 rat myoblasts fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Griffiths G.S., Grundl M., Leychenko A., Reiter S., Young-Robbins S.S., Sulzmaier F.J., Caliva M.J., Ramos J.W., Matter M.L. Apoptosis - Interactions involving proteins with a function related to apoptosis matter@hawaii.edu J. Biol. Chem. (0021-9258) 2011 Only protein-protein interactions imex curation fak1_rat Focal adhesion kinase 1 Ptk2 Fak Fak1 Focal adhesion kinase-related nonkinase Protein-tyrosine kinase 2 p125FAK pp125FAK protein protein rat Rattus norvegicus (Rat) Rat MAAAYLDPNLNHTPSSSTKTHLGTGTERSPGAMERVLKVFHYFESSNEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKLANNEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQISGYPGSHGIPAMAGSIYPGQASLLDQTELWNHRPQEMSMWQPSVEDSAALDLRGMGQVLPPHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSFQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLSNLSSISSPAESYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPILPASTHREIEMAQKLLNSDLGELISKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH q5xi86_rat Aminoacyl-tRNA hydrolase Ptrh2 RGD1306819 rCG_34306 protein protein rat Rattus norvegicus (Rat) Rat MLSKLLTMEYLVHPGTLSLAAGVACGMCLGWGLRSHLGIFPQNSTSETNRDTEMGTEASILGESGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQIQRRNPQVLKEWEYCGQPKVVVKAPDEDSLIQLLTHAKALGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKLY pth2_human Peptidyl-tRNA hydrolase 2, mitochondrial PTRH2 BIT1 PTH2 CGI-147 Bcl-2 inhibitor of transcription 1 protein protein human Homo sapiens Human MPSKSLVMEYLAHPSTLGLAVGVACGMCLGWSLRVCFGMLPKSKTSKTHTDTESEASILGDSGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY fak1_human Focal adhesion kinase 1 PTK2 FAK FAK1 pp125FAK Protein-tyrosine kinase 2 Focal adhesion kinase-related nonkinase Protein phosphatase 1 regulatory subunit 71 p125FAK protein protein human Homo sapiens Human MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH ptrh2-ptk2 1308556 n/a 1308559 unspecified role unspecified role prey prey n/a 1308560 unspecified role unspecified role bait bait physical association physical association false false false 9a ptk2-ptrh2-1 1308556 n/a 1308560 unspecified role unspecified role prey prey n/a 1308559 unspecified role unspecified role bait bait physical association physical association false false false 9a ptrh2-ptk2-1 1308557 n/a 1308561 unspecified role unspecified role bait bait n/a 1308562 unspecified role unspecified role prey prey physical association physical association false false false 9b ptk2-ptrh2-2 1308557 n/a 1308561 unspecified role unspecified role prey prey n/a 1308562 unspecified role unspecified role bait bait physical association physical association false false false 9b ptk2-ptrh2 1308558 n/a 1308560 unspecified role unspecified role neutral component neutral component n/a 1308559 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 8a