IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ goldberg-2010-4 Distinct factors control histone variant H3.3 localization at specific genomic regions. mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells ch-ip chromatin immunoprecipitation assay ch-ip nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". Some interactions are missing due to the use of non-specific anti-H3 antibodies. The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Cell (0092-8674) 2010 Only protein-protein interactions imex curation goldberg-2010-1 Distinct factors control histone variant H3.3 localization at specific genomic regions. mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells pull down pull down sequence tag sequence tag identification sequence tag Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Cell (0092-8674) 2010 Only protein-protein interactions imex curation goldberg-2010-2 Distinct factors control histone variant H3.3 localization at specific genomic regions. mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Cell (0092-8674) 2010 Only protein-protein interactions imex curation goldberg-2010-7 Distinct factors control histone variant H3.3 localization at specific genomic regions. mouse-neuronal_precursor_cells(stem cells) Mouse Neuronal precursor cells/neural stem progenitor cells neuronal_precursor (stem cells) Neuronal Precursor Cells/neural stem progenitor cells ch-ip chromatin immunoprecipitation assay ch-ip nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Cell (0092-8674) 2010 Only protein-protein interactions imex curation goldberg-2010-3 Distinct factors control histone variant H3.3 localization at specific genomic regions. human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 pull down pull down western blot western blot Immuno blot Immuno blot Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Cell (0092-8674) 2010 Only protein-protein interactions imex curation goldberg-2010-5 Distinct factors control histone variant H3.3 localization at specific genomic regions. mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells confocal microscopy confocal microscopy tag fluorescence tag visualisation by fluorescence tag fluorescence Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Cell (0092-8674) 2010 Only protein-protein interactions imex curation goldberg-2010-6 Distinct factors control histone variant H3.3 localization at specific genomic regions. mouse-embryonic_stem cell Mus musculus embryonic stem cell es cells embryonic stem cells ch-ip chromatin immunoprecipitation assay ch-ip predetermined predetermined participant predetermined Goldberg AD., Banaszynski LA., Noh KM., Lewis PW., Elsaesser SJ., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver RC., Miller JC., Lee YL., Boydston EA., Holmes MC., Gregory PD., Greally JM., Rafii S., Yang C., Scambler PJ., Garrick D., Gibbons RJ., Higgs DR., Cristea IM., Urnov FD., Zheng D., Allis CD. Apoptosis - Interactions involving proteins with a function related to apoptosis The Extended Experimental Procedures states: "Immunoaffinity purications of GFP-tagged H3.3, H3.2, H3.1, H3.3 etc.., and H3.2 HIRA etc.. were performed as previously described (Cristea et al., 2005)", yet the Experimental Procedures, the Image legend and text refer to "Immunoaffinity purifications of EYFP-tagged H3.3". The expression vector used contains a single GST-thrombin cleavage site-GFP/EYFP open reading frame. Cell homogenates were incubated with magnetic beads conjugated to rabbit polyclonal anti-GFP/anti-EYFP antibodies. Peptides obtained from tryptic digests of resultant SDS/PAGE gel bands were subject to MALDI MS and tandem mass spectrometry (MS/MS). gi|51701919|sp|P63049| Ubiquitin is a dog protein- this has been remapped to mouse. hnRNP G-T (ref XP_914797) the NCBI states "report removed", remapped to Q9DAE2 alliscd@rockefeller.edu, deyou.zheng@einstein.yu.edu Cell (0092-8674) 2010 Only protein-protein interactions imex curation h33_mouse Histone H3.3 H3-3a H3-3b H3.3a H3.3b H3f3a H3f3b protein protein mouse Mus musculus Mouse MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA telomeric_mouse_dna Mouse Telomere DNA probe dna deoxyribonucleic acid DNA deoxyribonucleic acid dna DNA deoxyribonucleic acid mouse Mus musculus Mouse TTAGGG fog2_mouse_gene Mouse ZFPM2 gene gene gene mouse Mus musculus Mouse actb_mouse_gene Mouse Beta ACTIN gene gene gene mouse Mus musculus Mouse rpb1_mouse DNA-directed RNA polymerase II subunit RPB1 Polr2a Rpii215 Rpo2-1 DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase III largest subunit protein protein mouse Mus musculus Mouse MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPASPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN gas5_mouse_gene Mouse Non coding RNA Gas5 gene gene gene mouse Mus musculus Mouse gtr3_mouse_gene Mouse SLC2A3 solute carrier type 2 gene gene gene mouse Mus musculus Mouse nanog_mouse_gene gene gene mouse Mus musculus Mouse err2_mouse_gene Mouse esrrb gene gene gene mouse Mus musculus Mouse ldha_mouse_gene Mouse L-lactate dehydrogenase A chain gene gene gene mouse Mus musculus Mouse rs19_mouse_gene Mouse 40S ribosomal protein S19 (RPS19) gene gene gene mouse Mus musculus Mouse pparg_mouse_gene Mouse Peroxisome proliferator-activated receptor gamma gene gene gene mouse Mus musculus Mouse ubiq_mouse Ubiquitin Rps27a Uba80 Ubcep1 Uba52 Ubcep2 Ubb Ubc protein protein mouse Mus musculus Mouse MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG hsp7c_mouse Heat shock cognate 71 kDa protein Heat shock 70 kDa protein 8 Hspa8 Hsc70 Hsc73 protein protein mouse Mus musculus Mouse MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD q9dae2_mouse Rbmxl2 protein protein mouse Mus musculus Mouse MVEADRPGKLFIGGLNLETDEKGLETAFGKYGRIIEVLLMKDRETSKSRGFAFVTFENPADAKAAARDMNGKSLDGKAIKVAQATKPVFESGRRGPPPPRSRGRPRGLRGTRGGGPRRPPSRGGSADEGGYTGDFDLRPSRAPMPLKRGPPPRRAGPPPKRAAPSGPARSGAGIRGRAAGSRGRDGYGGPPRRELPPPRRDPYLGPRDEGYSPRESYSSRDYPSARDPRDFAPSPRDYTYRDYGHSSARDECPSRGYCERDGYGGRERDYEHPSGGSYRDPFDSYGDPRGAGPARGPPPSYGGGRYDEYRGCSPDGYGGRDSYRSERYSSGRERVGRPERGLPPSVERNCPAPRDSYSRSGRRAPPRGGGRVGSRLERGGGRSRY macf1_mouse Microtubule-actin cross-linking factor 1 Actin cross-linking family 7 Macf1 Acf7 Aclp7 Macf protein protein mouse Mus musculus Mouse MSSSDEETLSERSCRSERSCRSERSYRSERSGSLSPCPPGDTLPWNLPLHEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQVQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATEVDSRWQEYQSRVDSLIPWIRQHTILMSDKSFPQNPVELKALYNQYIHFKETEILAKEREKGRIKELYKLLEVWIEFGRIKLPQGYHPNHVEEEWGKLIVEMLEREKSLRPAVERLELLLQIANKIQNGALNCEEKLTLAKNTLQADAAHLESGQPVQCESDVIMYIQECEGLIRQLQVDLQILRDEKYYQLEELAFRVMRLQDELVTLRLECTNLYRKGHFSSLELVPPSTLTTTHLKAEPLNKTTHSSSTSWFRKPMTRTELVSISSSEDEGNLRFVYELLSWVEEMQMKLERAEWGNDLPSVELQLETQQHIHTSVEELGSSVKEARLYEGKMSQNFHTSYVETLGKLETQYCKLKETSSFRMRHLQSLHKFVSRATAELIWLNGKEEEELACDWSDSNPNISAKKTYFSELTMELEGKQDVFRSLQDTAEVLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHVKENAAYFQFFSDARDLESFLRNLQDSIKRKYTCDRSTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIVQLKPRNPDHVLKSTLSVKAICDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPPNKEAIEMASRVEQSYQKVMALWHQLHINTKSLISWNYLRKDLDTVQTWSLEKLRSLAPGECHQVMKNLQAHYEDFLQDSHDSALFSVADRLRIEEEVEACKAHFQHLMKSLENEDKEETLAKVYISELKNIRLLLEECEQRLLKQIQSPASSKTDRDARQDITLRIAEQEHTQEDLQHLRSDLDAISMKCNVFLQQSPSGSSATTLRSELNLMVEKMDHVYGLSTVYLNKLKTIDVIVRSMQDAELLVKGYEIKLSQEEAVPADLSALESHRTTLQHWLSDVKDKNSVFSVLDEEITKAKKVAEQLRHPASEPNLDLERYQEKGSQLQERWHRVIAQLETRQSEVESIQEVLRDYRACHGTLIKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQTELFAEIERNQTKLDQCQKFSQQYSTIVKDYELQLMTYKAFVESQQKSPGKRRRMISSSDAITQEFMDLRTRYTALVTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKDLLGWVSTLARNTQGTTTSSHTSASADIEKAILEQQVLAEELTTKKEQVSEAIKTSQIFLAKHGHKLSEGEKEQISEQLRVLNKTYHDLCDGSANQLQQLQSELAQQTEQKGCRAVAGVIDLGTVEIFPIFRAMQKGLIDQDTGLVLLESQIIMSGLIDPENSEKLSLEEGLTRNFINLPIYQQLLGLRDSLSLVSRLTGTLGSLSVVEAIEKKIISERLGLKVLEVHLATGGFSLPPSENCINLEEAFHQGFIASSLHSELQSHLRSSKNLIDPNTAEKVGLLDLMQRCIIHQESGLKLLPVKQLAGGMVSLKSGRKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPRTGHRLTVEEAVRHNLIDQDMACAILIRQLQTGGIIDTVTGDRMTIDEAVTNNLVAAKIALVILESLWSFMGLLLPESGEILPITDALEQGIVSTELAHKILHNRQQIEALFLPTLTEIWSWEKATESGILDKDLVNNLRSVCIPDMMPHIQLADSAEQSKVGFAAGKPPVSGPREEGSSHGEKLLFQLMTHSYIHAHTGQRLLLLDQELVEMLTSRDDCQVILPEVFEIQHQRLNTSEALQELYTGTISQISSAKHPRKPCESQFLSQNKDYPSQENCTEAKGERSVVGIECSPAESPERELFLKEQEAIIENVGSLKVINKVKLKLQRPLLGSRKEEQAETLREENISGDPLLVECPEESEGKDLSTEKSKCQTPTKCSFTCHKEQVKTIKDIPSETGTSLIKSQNQMSQFQVDTSVGLRSEFKSEHDMNVNSLEKELKEELLVKDGHKQSQEGQSVADGQTVALEKTDTEDNADEPALLHSSPFEDATLSTLSAQLQDGGIFNEETGQKLLLNEAIAQGLVSSHTAVKLMGKLNMFRGFFDSQTCESLTTEEVIDEGLMDEKLLYNVLMSDKAISGILDPRTHSLCSVKEAVAAGLLDKETATRILEGQVITGGIVDLKRGKKLSVTLASNLGLVDTADQTELINLEKATKGRGAEKAVKERLIELQMETAGLMDPESKAPLTVLQSIDRGILEREAAVYLLTKQVLDGGIIHHISGLRLSVDNAFKHGLIGEDMARQLRKVENFIHYQFFHPQTKEALSFSEAIKLDLVSPDLKREIQEIQDFSGNLGDFIYGQKLTLAKTNKEESLANKTELPSGVMHGVIDPENCTIIPYSELVKKCRIDTESGWRYLEVIPFSDIKDEAGNNVLTPPEAIQLGKVDFASALKVLEAQANTGGIIDMATGKRVTLASALEKKLLDENMARIIASHQMLSGGIIDIYSDQRVTLNDAVEKRLISPELAAMIQVDPLAEQGGTGVCELKGDFLRKELLSESSKTPRESYSKEKHEAVLQAGSLCAPEKAGIRGSNGEKAEKGRKISVEMEGQRQDEKASSDSKVSASILSPFGFEGESSYQVSVTHPCSESCDLKPREETRSCMKKCAVVERDKVVTQIKMVSHVKQSTSGLDAEEARERQGRMVSKEQGSHYETAGNLLSERSVRVDRRVRREMGGEQSVQMSREAAVLSEEESDQEVTIGDEPDSFVKSQSMKMIGNDKGKEAGIEKDISVVCKIEGFPSQMTSKDASLTNQDALPFYTEGETKTVNLCSILKPGEKLSQETASTVQKEPLSSEIPRPERLNSQESDEEPQISDVPHISKGDMAAQITTRQETTDVQDLYITSKSSETKDKIFPSKNYIEKLHQEIPMDPTRSHKLKEATISTLETEGISYLDSSDIKSLCEDSKADHKSCGHQKSKVTTTQAKKSLEVVDLLVRDTEEGSSEDRVGQRGPRVLASLLPEKLPTRTVQSENIRQHDAVIPAISEIREEMALSLPCSVVKVDGKIPKEKHKEILGDEQGPFMAIPSGKGIEGVNPEPCRATQNVFTRRLCLEHDEKLVSYLSLLRDIEMRTKQIQPLELNVAELQDLLGQAKELDRELKDLSTVVSQELECVDRIVISQPQEVPAQLLKALEKDAKNLQKSLDSVSDSWSSRFLHLQSAVEVKKATVLNRHKELQGKLQDLRAWVGRASLTLNSKGCDTETDADSLSHTLQPYKDMKQSMAERKSQLDALALDIQLFISEHPQDLSLQQNQEMLQFLSELQRSFQGLVEHTAAQKDVVQGHLQQVQQEVQVKTLQKQQDTCHKKLEDLCNWVGQAERALERHQGGSSSGKSSLLCAEPKVDLKDLQGDIQSHSTSFATAVKDIEGFLEENQTKLSPQELTALREKLHQAKEQYEVLQERTRVAQKELEEAVTSALQQETEKSKAATELAENKRKIDALLDWVGLLWGHLRESHRLAFQEWSSSLELAMEKQTLAATDGHVDVNQVPETLDRQYELMKARHQELLSQQQNFIVATQSVQSFLDQHSHNLTPEERQKLQEKLGELKEQYAASLARSEAELKQTQALRDELQKFLQDHKEFENWLQQSENELDSMHKGGSSPEALNSLLKRQGSFSEDVISHKGDLRFVTISGQKVLETENNFEEGQEPSATRNLVNEKLKDATERYTTLHSKCIRLGSHLSMLLGQYQQFQSSADSLQAWVLTCEASVGKLLSDTVASDPGVLQQQLATTKQLQEELAEHQVPVEKLQKAAHDLLDIEGEPALDCRPIQETTDSISSRFQNLSCSLDERSALLQKAIAQSQSVQESMESLLQSIREVEQNLERDQVASLSSGVIQEALANNMKLKQDIARQKSSLEATHDMVTRFMETADSNSASVLQGKLAELSQRFQQLQLQQQEKESNLKKLLPQAEMFEQLSNKLQQFMENKSRLLASGNQPDQDIAHFSQQIQELTLAMEDQKENLDTLEHLVTTLGSCGFALDLSQHQDKIQNLKKDFTELQKTVQEREKDASTCQEQLDEFRKLIRTFQKWLKETEGNVPPAKTFVSAKELEKQIEHLKDLISDWESKGALLGEINAKGTALESLIMDITAPDSQAKTGSILPPVGSSVGSVNGYHTCKDLTEIQCDMFDVNSKYEKLWEVLRERQESLQTVFSRMEEVQKEASSVLQWLESKEEVLKAMDATLSPTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLKTYPNSQEAENWKKMQEDLNSRWEKATEVTVARQKQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLSIDPNMLKQQVQFMLKEFEARRQQHEQLNEAAQGILTGPGDMSPSASQVHKDLQSISQKWVELTDKLNSRSSQIDQAIVKSTQYQDLLQDLSEKVKAIGQRLSGQSAISTQPEAVKQQLEETSEIRSDLGQLDNEIKEAQTLCQELSLLIGEQYLKDELKKRLETVALPLQGLEDLAADRMNRLQAALASTQQFQQMFDELRTWLDEKQSQQAKNCPISAKLERLQCQLQENEEFQKNLNQHSGSYEVIVAEGEALLLSVPPGEEKKTLQNQLVELRSHWEDLSKKTANRQSRLKDCMQKAQKYQGHVEDLVPWIDECKSKMSELQVTLDPVQLESSLLRSKAMLNEAEKRRSLLEILNSAADILINSSEIDEDEIRDEKAGLNQNMDAITEELQAKTSSLEEMTQRLKEFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEKLKAQQEVLQALEPQVDYLRNFTQGLVEDAPDGSDASPLVHQAEVAQQEFLEVKQRVSSSCLTMENKLEGIGQFHCRVREMFSQLADLDDELDGMGAIGRDTDSLQSQIEDVRLFLNKIQALRFDIEDSEAECRKMLEEEGTLDLLGLKRELEALNKQCGKLTERGKVRQEQLELTLGRVEDFYRKLKALNDAATAAEEGEALQWIVGTEVDVINQQLADFKLFQKDQVDPLQVKLQQVNGLGQGLIQSAGKNCDVQGLEHDMDEINTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEELIANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQSAELADREKITGQLESLERRWTDLLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTANKLANSEPVGTQTAKIHQQIIRHKALNEEIINRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIKTRYADITLTSSKALRTLEQARQLATKFHSTYEELTGWLREAEEELAASGGQSPTGEQIPQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLISDTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRGEIFSTCGEEQKAVLQEKTECLIQQYEAVSLLNSERYARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESIAEHKPHIDKILKIGPQLKELNPEEGKMVEEKYQKAENMYAQIKDEVRQRALALDEAVSQSAQFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARSEEREIKFLDVLELAEKFWYDMAALLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVKKSIDEMNNAWENLNKTWKERLEKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVATVNKAGSELLESSAGDDASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELNRMENQLSASKPTGGLPETAREQLDTHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSGSKTEQSVALLEQKWHAVSSKVEERKSKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPPSLILNTVLSQIEEHKVFANEVNDHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLAGDTQKLDNLLGEVRDKWDTVCGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIEGSRDDTTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNTAVAMGEAILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQPDVDRVTKTYKRKSVEPTHAPFMEKSRSGSRKSLNQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQRKLNDALDRLEELCPELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVISSSGSKLKRPTPAFHSSRTSLAGDTSNSSSPASTGAKANRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGSSRRGLTKPSKIPTMSKKTTTASPRTPGPKR hat1_mouse Histone acetyltransferase type B catalytic subunit Hat1 Histone acetyltransferase 1 protein protein mouse Mus musculus Mouse MAALEKFLVEYKSAVEKKLAEYKCNTNTAIELKLVRFPEDLENDIRTFFPEYTHQLFGDDETAFGYKGLKILLYYIAGSLSTLFRVEYSSKVDENFDCVEADDVEGKIRQIIPPGFCTNTNDFLSLLEKETNFKPFGTLLHTYTVPSQTGGETFTFQIHKADMTCRGFREYHERLQTFLMWFIETASFIDVDDERWHYFLVFEKYNKDGATLFATVGYMTVYNYYVYPDKTRPRVSQMLILTPFQGQGHGAQLLETVHRYYISFPTVLDITAEDPSRSYLKLRDFVLVKFCQFLPSFSRERLLQGFSEDMAIQAQQMFKINKQHARRVYEILRLLVTDMSDAEQYRSYRLDIKRRLISPYKKKQRDLAKMKKCLRPEELTNQMNQIEISVQHEQLEERFQELVEDYRRVIERLAQE q71lx8_mouse Hsp90ab1 Hsp84b Hspcb protein protein mouse Mus musculus Mouse MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRMEEVD h4_mouse Histone H4 H4c11 H4c12 H4c14 H4c2 H4c3 H4c4 H4c6 H4c8 H4c9 H4f16 Hist1h4a Hist4h4 Hist1h4b Hist1h4c Hist1h4d Hist1h4f Hist1h4h Hist1h4i Hist1h4j Hist1h4k Hist2h4a Hist2h4 Hist1h4m H4-53 H4-12 H4c1 protein protein mouse Mus musculus Mouse MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG q3v122_mouse DNA replication licensing factor MCM7 Mcm7 MCM7 protein protein mouse Mus musculus Mouse MALKDYAIEKEKVKKFLQEFYYENELGKKQFKYGTQLVHLAHREQVALYVDLDDIAEDDPELVDSICENAKRYSRLFGDVVQELLPEYKEKEVVNKDVLDVYIEHRLMMEQRSRDPGAVRNPQNQYPSELMRRFELYFRGPSSSKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFVKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRIAQPGDHVSVTGIFLPVLRTGFQQMAQGLLSETYLEAHWIVKMTKSDDDVSGAGELSSEELKQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLLVGGVDQSPQGMKIRGNIHICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNVQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPAQFEPLDMKLMRRYIAMCHERQPTVPESLADYITAAYVEMRREARASKDATYTSARTLLAILRLSTALARLRMVDIVEKEDVNEAIRLMEMSKDSLLGEKGQTARTQRPADVIFATIRELVSRGRSVHFSEAEQRCISRGFTPAQFQAALDEYEELNVWQVNTSRTRITFV mcm2_mouse DNA replication licensing factor MCM2 Minichromosome maintenance protein 2 homolog Nuclear protein BM28 Mcm2 Bm28 Cdcl1 Kiaa0030 Mcmd2 protein protein mouse Mus musculus Mouse MAESSESLSASSPARQRRRISDPLTSSPGRSSRRADALTSSPGRDLPPFEDESEGLLGTEGPMEEEEDGEELIGDGMERDYRPIPELDVYEAEGLALDDEDVEELTASQREAAERTMRQRDREAGRGLGRMRRGLLYDSSEEDEERPARKRRHVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCSKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEINMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATIILANHVAKKDNKVAVGELTDEDVKMITGLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDVLCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKKDEGLTNGGTLEPAMPNTYGVEPLPQEVLKKYIIYAKERVRPKLNQMDQDKVARMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVMEDDVNMAIRVMMESFIDTQKFSVMRSMRKTFARYLSFRRDNNDLLLFILKQLVAEQVTYQRNRFGAQQDTIEIPEKDLMDKARQINIHNLSAFYDSDLFKFNKFSRDLKRKLILQQF mcm6_mouse DNA replication licensing factor MCM6 Mis5 homolog Mcm6 Mcmd6 Mis5 protein protein mouse Mus musculus Mouse MDLAAAAEPGAGSQHPEVRDEVAEKCQKLFLDFLEEFQGSDGEIKYLQFAEELIRPERNTLVVSFADLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIPFAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIKDVEQQFKYTQPNICRNPVCANRKRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDRCDFTGALIVVPDVSKLSTPGARAETNSRVSGADGYETEGIRGLRALGVRDLSYRLVFLACHVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVDEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDMRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKRLRQRDGSGVTKSSWRITVRQLESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMETDEGQGGVNGHADSPAPVNRFNGSSEDASQETVSKPSLRLGFAEYCRISNLIVLHLRKMEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKTIIEKVVHRLTHYDHVLIELTQAGLKGSSEGSESYEEDPYLVVNPNYLLED q8cgp4_mouse Histone H2A H2ac1 Hist1h2aa protein protein mouse Mus musculus Mouse MSGPTKRGGKARAKVKSRSSRAGLQFPVGRVHRLLRQGNYAQRIGAGAPVYLAAVLEYLTAEVLELAGNAARDNKKTRITPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHKSQTK h2b1m_mouse Histone H2B type 1-M H2bc14 H2B 291B Hist1h2bm protein protein mouse Mus musculus Mouse MPEPTKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK atpb_mouse ATP synthase subunit beta, mitochondrial Atp5f1b ATP synthase F1 subunit beta Atp5b protein protein mouse Mus musculus Mouse MLSLVGRVASASASGALRGLSPSAALPQAQLLLRAAPAGVHPARDYAAQASAAPKAGTATGRIVAVIGAVVDVQFDEGLPPILNALEVQGRDSRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKTKQFAPIHAEAPEFIEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGNEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHGS asf1b_mouse Histone chaperone ASF1B Asf1b Anti-silencing function protein 1 homolog B protein protein mouse Mus musculus Mouse MAKVSVLNVAVLENPSPFHSPFRFEISFECSEALSDDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYPDPELRENPPPKPDFSQLQRNILASNPRVTRFHINWDNNPDSLEAIENQDPNVDFSLSLSCTPVKSLGLPSCIPGLLPENSMDCI h2az_mouse Histone H2A.Z H2az1 H2afz H2az protein protein mouse Mus musculus Mouse MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV asf1a_mouse Histone chaperone ASF1A Asf1a Anti-silencing function protein 1 homolog A protein protein mouse Mus musculus Mouse MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAESEEYDQVLDSVLVGPVPAGRHMFVFQADAPNAGLIPDADAVGVTVVLITCTYRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFHINWEDNTEKLEDAESSNPNLQSLLSTDALPSASKGWSTSENSLNVMLESHMDCM q3uj03_mouse Poly [ADP-ribose] polymerase Parp1 protein protein mouse Mus musculus Mouse MAEASERLYRVEYAKSGRASCKKCSESIPKDSLRMTIMVQSPMFDGKVPHWYHFSCFWKVGHSIRQPDVEVDGFSELRWDDQQKVKKTAEAGGVAGKGQDGSGGKAEKTLGDFLAEYAKSNRSMCKGCLEKIEKGQMRLSKKMVDPEKPQLGMIDRWYHPTCFVKKRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAIKNEGKRKGDEVDGTDEVAKKKSKKGKDKDSSKLEKALKAQNELIWNIKDELKKACSTNDLKELLIFNQQQVPSGESAILDRVADGMAFGALLPCKECSGQLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKGFREISYLKKLKVKKQDRIFPPESSAPAPLALPLSVTSAPTAVNSSAPADKPLSNMKILTLGKLSQNKDEAKAVIEKLGGKLTGSANKASLCISTKKEVEKMSKKMEEVKAANVRVVCEDFLQDVSASTKSLQELLSAHSLSSWGAEVKAEPGEVVAPKGKSAAPSKKSKGAVKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVRGTNSYYKLQLLEDDKESRYWIFRSWGRVGTVIGSNKLEQMPSKEDAVEHFMELYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKPVQELVGMIFDVESMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQAVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSASITLEGVEVPLGTGIPSGVNDTCLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW q68fn3_mouse Ubr7 protein protein mouse Mus musculus Mouse GSHKLFELYTKRNFRCDCGNSKFKNLECKLFPDKSKVNSCNKYNDNFFGLYCVCKRPYPDPEDEVPDEMIQCVVCEDWFHGRHLGAIPPESGDFQEMVCQACMRRCSFLWAYAAQLAVTRISAEDDGLLPNATGMGDEDVSKPENGAPQDNGLKEDAPEHGRDSVNEVKAEQKNEPCSSSSSESDLQTVFKKENIKTEPQSSCRLQELQAKQFVKKDAATYWPLNWRSKLCTCQDCMKMYGELDVLFLTDECDTVLAYENKGKNDQATDRRDPLMDTLSSMNRVQQVELICEYNDLKTELKDYLKRFADEGTVVKREDIQQFFEEFQSKKRRRVDGLQYYCS b1au75_mouse Nuclear autoantigenic sperm protein Nasp protein protein mouse Mus musculus Mouse MATESTAAAAIAAELVSADKIEDAPAPSTSADKMESLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNVDEEAREELREQVYDAMGEKEAKKAEGKSLTKPETDKEQESEVEKGGREDMDISEPEEKLQETVEPTSKQLTESSEEAKEAAIPGLNEDEVASGKTEQESLCTEKGKSISGAYVQNKEFRETVEEGEEIISLEKKPKETSEDQPIRAAEKQGTLMKVVEIEAEIDPQVKSADVGGEEPKDQVATSESELGKAVLMELSGQDVEASPVVAAEAGAEVSEKPGQEITVIPNNGPVVGQSTVGDQTPSEPQTSAERLTETKDGSSVEEVKAELVPEQEEAMLPVEESEAAGDGVETKVAQRATEKAPEDKFKIAANEETQERDEQMKEGEETEGSEEEDRENDKAEETPNESVLEKKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYIQAVEEFQACLSLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFGKSIDVIEKRMAVLHEQMKEAEGSFTEYEKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPSGAGASVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVSSGKEVSENMEAEAENQAESQTAEGTVESAATIKSTAC sp16h_mouse FACT complex subunit SPT16 Supt16h Fact140 Factp140 Facilitates chromatin transcription complex subunit SPT16 FACT 140 kDa subunit FACTp140 Chromatin-specific transcription elongation factor 140 kDa subunit Supt16 protein protein mouse Mus musculus Mouse MAVTLDKDAYYRRVKRLYSNWRKGEDEYASIDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLVREKNESNKSSFDKMIDAIKESKSGKKIGVFSKDKFPGEFMKSWSDCLNKEGFDKVDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPTQEVQENYNFLLQLQEELLKELRHGVKICDVYNSVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATILTSVKKKVKNVGIFLKNEDDEEEEEEKDEAEDLLGRGSRAALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMPKEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEGNIFPNPEATFVKEITYRASNMKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQDSLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDGEMIIVLHFHLKNAVMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTAFKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIHFERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPEGFFEQGGWSFLEPEGEGSDAEDGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSSAPPKKKRK dhx9_mouse ATP-dependent RNA helicase A Dhx9 Ddx9 Nuclear DNA helicase II DEAH box protein 9 RNA helicase A protein protein mouse Mus musculus Mouse MGDIKNFLYAWCGKRKMTPAYEIRAVGNKNRQKFMCEVRVEGFNYAGMGNSTNKKDAQSNAARDFVNYLVRINEVKSEEVPAVGIVPPPPILSDTSDSTASAAEGLPAPMGGPLPPHLALKAEENNSGVESSGYGSPGPTWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDHNRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVIEAYSGLTKKKEGERVEPYKVFLSPDLELQLQNVVQELDLEIVPPPVDPSMPVILNIGKLAHFEPSQRQNAVGVVPWSPPQSNWNPWTSSNIDEGPLAYASTEQISMDLKNELTYQMEQDHNLQSVLQERELLPVKKFEAEILEAISSNSVVIIRGATGCGKTTQVPQYILDDFIQNDRAAECNIVVTQPRRISAVAVAERVAYERGEEPGKSCGYSVRFESILPRPHASIMFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVLAYPEVRIVLMSATIDTTMFCEYFFNCPIIEVYGRTFPVQEYFLEDCIQMTQFIPPPKDKKKKDKEDDGGEDDDANCNLICGDEYGPETKLSMSQLNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLENNSHFGSHRYQILPLHSQIPREEQRKVFDPVPDGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFDRLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAIIEAEHTLRELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAVCTISAATCFPEPFISEGKRLGYIHRNFAGNRFSDHVALLSVFQAWDDARMSGEEAEIRFCEQKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLTQVFTNTGPDNNLDVVISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVFIDDWIRLQISHEAAACITIRAAMEALVVEVSKQPNIISQLDPVNEHMLNTIRQISRPSAAGINLMIGSVRYGDGPRPPKMARYDNGSGYRRGYGGGGYGGGGYGGGYGSGGFGGGFGSGGGFGGGFNSGGGGFGSGGGGFGSGGGGFGGGGGGFSGGGGGGFGGGRGGGGGGFGGSGGFGNGGGGYGVGGGGYGGGGGGGYGGGSGGYGGGGYGGGEGYSISPNSYRGNYGGGGGGYRGGSQGGYRNNFGGDYRGSSGDYRGSGGGYRGSGGFQRRGYGGGYFGQGRGGGGGGGY hira_mouse Protein HIRA Hira Tuple1 TUP1-like enhancer of split protein 1 protein protein mouse Mus musculus Mouse MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRSHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKNATTRETSSASSVTGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSSSLAGTMLSSPSGQQLLPLDSSTPSFGASKPCTEPVAATSARPTGESVSKDSMNATSTPAASSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPSLTSVIPTAVERLKEQNLVKELRSRELESSSDSDEKVHLAKPSSLSKRKLELEVETVEKKKKGRPRKDSRLLPMSLSVQSPAALSTEKEAMCLSAPALALKLPIPGPQRAFTLQVSSDPSMYIEVENEVTTVGGIRLSRLKCNREGKEWETVLSSRVLTAAGSCDVVCVACEKRMLSVFSTCGRRLLPPILLPSPISTLHCTGPYVMALTAAATLSVWDVHRQVVVVKEESLHSILSGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRNSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDLLGPVHCSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK dnm3a_mouse DNA (cytosine-5)-methyltransferase 3A DNA methyltransferase MmuIIIA Cysteine methyltransferase DNMT3A Dnmt3a protein protein mouse Mus musculus Mouse MPSSGPGDTSSSSLEREDDRKEGEEQEENRGKEERQEPSATARKVGRPGRKRKHPPVESSDTPKDPAVTTKSQPMAQDSGPSDLLPNGDLEKRSEPQPEEGSPAAGQKGGAPAEGEGTETPPEASRAVENGCCVTKEGRGASAGEGKEQKQTNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEENQASGESQKVEEASPPAVQQPTDPASPTVATTPEPVGGDAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPACHDSDESDSGKAVEVQNKQMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTTEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV dnjc9_mouse DnaJ homolog subfamily C member 9 Dnajc9 protein protein mouse Mus musculus Mouse MGLLELCEQVFGTADLYQVLGVRREASDGEVRRGYHKVSLQVHPDRVEEDQKEDATRRFQILGRVYAVLSDKEQKAVYDEQGTVDEDSAGLNQDRDWDAYWRLLFKKISLEDIQAFEKTYKGSEEELNDIKQAYLDFKGDMDQIMESVLCVQYTDEPRIRNIIQKAIESKEIPAYSAFVKESKQKMNARKRRAQEEAKEAELSRKELGLEEGVDNLKALIQSRQKDRQKEMDSFLAQMEAKYCKPSKGGKRTALKKEKK q3uji2_mouse CAF1C_H4-bd domain-containing protein Rbbp7 protein protein mouse Mus musculus Mouse MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDSRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTASELEGQGS ssrp1_mouse FACT complex subunit SSRP1 Ssrp1 Facilitates chromatin transcription complex subunit SSRP1 Structure-specific recognition protein 1 Recombination signal sequence recognition protein 1 T160 protein protein mouse Mus musculus Mouse MAETLEFNDIFQEVKGSMNDGRLRLSRQGIIFKNSKTGKVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVSQCTTGKNEVTLEFHQNDDAEVSLMEVRFYVPPTQEDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARGTTTTRSFDFEIETKQGTQYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGINPGYDDYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASASSSSNEGDSDREEKKREQLKRAKMAKDRKSRRKSSEAKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARREYEKAMKEYEGGRGDSSKRDKSKKKKKVKAKMEKKSTPSRGSSSKSSSRQLSDSFKSKEFVSSDESSSGENKSKKKRRRSEDSEEELASTPPSSEDSASGSDE rbbp4_mouse Histone-binding protein RBBP4 Rbbp4 Rbap48 Retinoblastoma-binding protein 4 Retinoblastoma-binding protein p48 Chromatin assembly factor 1 subunit C Chromatin assembly factor I p48 subunit Nucleosome-remodeling factor subunit RBAP48 protein protein mouse Mus musculus Mouse MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS smca5_mouse SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Smarca5 Snf2h Sucrose nonfermenting protein 2 homolog protein protein mouse Mus musculus Mouse MSSAVEPPPPPPPESAPSKPSAAGAGGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRVKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDTESSVYNFEGEDYREKQKIAFTEWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRSPDLPNAAQAQKEEQLKIDEAEPLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAREVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKAPFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGPKPSTQKRKMDGAPDGRGRKKKLKL rgs9_mouse Regulator of G-protein signaling 9 Rgs9 protein protein mouse Mus musculus Mouse MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMHNQRVLVTSVPHAMTGGDVLQWITQRLWISNLEAQNLGNFIVKYGYIYPLQDPKNLILKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYDFLNKKINYKWDFVIMQAKEQYRTGKERNKADRYALDCQEKAYWLVHRSPPGMNNVLDYGLDRVTNPNEVKKQTVTAVRKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQETTKRSSTLPFMRRHLRSSPSPVILRQLEEEEKAREAANTVDITQPGQHLAPSPHLAVYTGTCVPPSPSSPFSPSCRSPRKPFASPSRFIRRPSIAICPSPSRVALEGSSGLEPKGEASWSGANSGPSVTENREPSADHSRPQPRAPPKARAALSLGRFLRRGCLASPVFARLSPKCPSVSHGKVQPLGDMGQQLPRLKPKKVANFFQIKMEMPTDSGTCLMDSDDPRAGESGDQTTEKEVICPWESLAEGKAG daxx_mouse Death domain-associated protein 6 Daxx Daxx protein protein mouse Mus musculus Mouse MATDDSIIVLDDDDEDEAAAQPGPSNLPPNPASTGPGPGLSQQATGLSEPRVDGGSSNSGSRKCYKLDNEKLFEEFLELCKTETSDHPEVVPFLHKLQQRAQSVFLASAEFCNILSRVLARSRKRPAKIYVYINELCTVLKAHSIKKKLNLAPAASTTSEASGPNPPTEPPSDLTNTENTASEASRTRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSSYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGLDTFPDYGDVLRAVEKAATRHSLGLPRQQLQLLAQDAFRDVGVRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPTLARRLRENRTLAMNRLDEVISKYAMMQDKTEEGERQKRRARLLGTAPQPSDPPQASSESGEGPSGMASQECPTTSKAETDDDDDDDDDDDEDNEESEEEEEEEEEEKEATEDEDEDLEQLQEDQGGDEEEEGGDNEGNESPTSPSDFFHRRNSEPAEGLRTPEGQQKRGLTETPASPPGASLDPPSTDAESSGEQLLEPLLGDESPVSQLAELEMEALPEERDISSPRKKSEDSLPTILENGAAVVTSTSVNGRVSSHTWRDASPPSKRFRKEKKQLGSGLLGNSYIKEPMAQQDSGQNTSVQPMPSPPLASVASVADSSTRVDSPSHELVTSSLCSPSPSLLLQTPQAQSLRQCIYKTSVATQCDPEEIIVLSDSD atrx_mouse Transcriptional regulator ATRX Xnp ATP-dependent helicase ATRX HP1 alpha-interacting protein HP1-BP38 protein Heterochromatin protein 2 X-linked nuclear protein Atrx Hp1bp2 protein protein mouse Mus musculus Mouse MTAEPMSGNKLSTLVQKLHDFLAHSSEESEETCSSPRLVMNQSTDKICGSGLNSDMMENNKEEGASTSEKSRSSGSSRSKRKPSIVTKYVESDDEKPTDENVNEKAATENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKADNLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLKVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICQPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKTSKVCDQTSKFSPKKSSSSCNGEEKKLEESCSGSVSSTYSHSALSVPKEMIKKTTKLIETTSNMNSSYIKFLKQAADNSEMTSAMKLCQLKSFKSVLDDIKKAHLALEEDLNSEIQALDDVHKEKNTKDLKSTDAKSETKLGKGEKSYSTEKREFLKLDARSSVKAIDGEEQRAHKSTSGEHKGSGRKDGSQYEPTNTPEDLDMDIVSVPSSVPEDIFDSLESAMEVQSSADYQGDGNSGTEPELESSSVKLNVSSKDSRGNIKSKVTAKVRKELFVKLTPVSLSNSPIKGVDCQEVSQEKNGRKSSGVARSSEKCRPREEISDHENNVTILLEDSDLRRSPRVKTTPLRRQTESNPAMSNSDEESNGTMKEKQKMSGPIRKKDKRNSADCATDNPKPHKVPKAKQPVIGDQNSDSDEMLAVLKEASQMGHSSSSDTDINEPQMNHKGKTGKDDNGKRKRKNSTSGSDFDTKKGKSTETSIISKKKRQNYSESSNYDSELEREIKTMSRIGAARKSVPEKKEEDSSEDEKQGKKVVDNGGHERAKTTQEGSSADDTGDTEGRQGGSCSIAGGSIEKVRSGVEFREMLCKPGVSSDGAEKPSVKEENVNSPEDKRVSKTKEKTKHLRSRQSRKGKGGSSDGTDRFPKKEQSDESSEGEKKQSRQRPGTKGKKAPDLKGETLKREQEWDSSSDGTERLPEEEEIGPFSKGIKQSKTDTAGGEKKGKKWKDKSCEKKEELSDSVDKLPGKGDSCDSSEDKKTRNRVSLREKKRFSLPAKSPGKRPECSSSDTEKSLKGQCCDSTEKRPKRIDLRERRNSSSKRNTKEVKSASSSSDAEGSSEDNKKQKKQRTSAKKKTGNTKEKKRNSLRATPKRKQVDITSSSSDIGDDDQNSAGEESSDEQKIKPVTENLVLPSHTGFCQSSGDEALSKSVPATVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPDGGGKKRIGKQSEESPADDGELRREQLAVNQVNSESDSDSEESKKPRYRHRLLRHKLTLSDGESGEEKPTKPKEHKEAKGRNRRKVSSEDSEDTDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSHSEEDKKEGDEEDEEDEDEDEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDENEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVEKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLNDNEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKDIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIKSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTAIQCKLYQYYLDHLTGVGNSTEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSKSLSSDEKKKPKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGDGNVDDTGNNPSVSLKLDESKTTSTSNPSSPAPDWYKDFVTDTDAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKEKPLIYKGEGKWIRNIDYYRLDGSTNAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVTFTSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSMTAVRIQPLEDIISTVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLINCVQRILMNRRLQQQYTQQQQQQLTYQQATLSHLMMPKPPNLIMTPSNYQQIDMRGMYQSVAGGMQPPPLQRAPPPTVRSKNPGPSPGKSM h32_mouse Histone H3.2 H3c13 H3c14 H3c15 H3c2 H3c3 H3c4 H3c6 H3c7 H3-143 H3-53 H3-B H3-F H3-clustered histone 13 H3-clustered histone 14 H3-clustered histone 15 H3-clustered histone 2 H3-clustered histone 3 H3-clustered histone 4 H3-clustered histone 6 H3-clustered histone 7 H3.2 H3.2-221 H3.2-614 H3.2-615 H3.2-616 H3b H3f Hist1h3b Hist1h3c Hist1h3d Hist1h3e Hist1h3f Hist2h3b Hist2h3c1 Hist2h3c2 Hist2h3ca1 Hist2h3ca2 protein protein mouse Mus musculus Mouse MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA h31_mouse Histone H3.1 H3c1 H3c10 H3c11 H3c8 H3.1-221 H3.1-291 H3.1-I H3a H3g H3h H3i Hist1h3a Hist1h3g Hist1h3h Hist1h3i protein protein mouse Mus musculus Mouse MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA egfr_mouse_gene gene gene mouse Mus musculus Mouse daxx_human Death domain-associated protein 6 DAXX BING2 DAP6 Daxx Fas death domain-associated protein ETS1-associated protein 1 protein protein human Homo sapiens Human MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYKLENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARHSLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVATQCDPEEIIVLSDSD atrx_human Transcriptional regulator ATRX ATRX RAD54L XH2 ATP-dependent helicase ATRX X-linked helicase II X-linked nuclear protein Znf-HX protein protein human Homo sapiens Human MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM h33_human Histone H3.3 H3-3A H3-3B H3.3A H3.3B H3F3 H3F3A H3F3B PP781 protein protein human Homo sapiens Human MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA h3_3_telomere 910148 n/a 910155 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n/a 910156 unspecified role unspecified role prey prey association association false false false Fig 7B. Atrx, but not Hira, is specifically required for H3.3 enrichment at telomeres. Histone H3.3 binds to a telomere (TTAGGG)Xn repeat array probe. Hira -/-, Atrx-null and Atrx-flox ES cells were used, H3.3 enrichment being the greatest in Hira -/- cells (> X10). h3_3_zfpm2 910148 n/a 910157 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false association association false false false Fig 2G. H3.3 is enriched around the TSS, but not into the gene body of the H3K4me3/H3K27me3 bivalent and transcriptionally repressed Zfpm2 gene. Mutation of H3.3 toward H3.2 or H3.1 abolishes this enrichment. h3_3_actb 910148 n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n/a 910158 unspecified role unspecified role prey prey association association false false false Fig 2H and S7B. H3.3 binding is enriched in the body of active genes, but not that of repressed genes. This enrichment often extends beyond the gene body and past the transcriptional end site (TES) at highly expressed genes in ESCs. No enrichment of H3.3 binding is seen in Hira -/- ES cells. rpb1_actb-1 910148 n/a 910159 unspecified role unspecified role bait bait ser5 opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations certain certain sequence position certain certain certain sequence position certain false n/a 910158 unspecified role unspecified role prey prey association association false false false Fig 2H. Binding of the RPB1 subunit of RNPII to the Actin B gene mainly occurs around the TSS and post TES. The distribution of post-TES peaks of serine-5-phosphorylated RNAPII are closely colocalized with peaks of H3.3, at active genes. rpb1_gas5 910148 n/a 910160 unspecified role unspecified role prey prey n/a 910159 unspecified role unspecified role bait bait ser5 opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations certain certain sequence position certain certain certain sequence position certain false association association false false false Fig 2I. H3.3 and RNAPIISer5p are enriched around the TSS and into the body of the noncoding RNA gene Gas5, but less enriched in the gene body of the neighboring low expressing Zbtb37 gene in ESCs. h3_3_gas5 910148 n/a 910160 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false association association false false false Fig 2I. In ESCs, H3.3 and RNAPIISer5p are enriched around the TSS, the gene body and the region after the TES, of the noncoding RNA gene Gas5, but less enriched in the gene body of the neighboring low expressing Zbtb37 gene. h3_3_nanog 910148 n/a 910161 unspecified role unspecified role prey prey n/a 910162 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false association association false false false Fig S3B In ES cells H3.3 is enriched at the TSS of Nanog and slc2a3 genes and also around the intergenic and genic TFBS near the Nanog gene. H3.3-specific enrichment is lost upon mutation of H3.3B to H3.2 or H3.1S31. At the 5' and 3' regions of the Nanog gene, H3.3 enrichment is reduced but partially maintained on differentiation of ESCs to NPCs. h3_3_esrrb 910148 n/a 910163 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false association association false false false Fig 3A. H3.3 is enriched in the gene body of the highly expressed pluripotency gene Esrrb in ESCs, and this enrichment is largely lost upon differentiation to NPCs. h3_3_ldha-1 910148 n/a 910164 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false association association false false false Fig 3C. H3.3, H3K4me1, and H3K36me3 are enriched in the gene body of the housekeeping gene lactate dehydrogenase A (Ldha) in both ESCs and NPCs and is not enriched in the neighboring Ldhc gene. H3K4me3 is enriched at the Ldha TSS for both ESCs and NPCs. h3_3_rps19 910148 n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n/a 910165 unspecified role unspecified role prey prey association association false false false Fig 4G. H3.3 enrichment at the active, ribosomal-protein coding gene Rps19 is Hira dependent. h3_3_pparg 910148 n/a 910166 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false association association false false false Fig 4G. H3.3 enrichment at the repressed bivalent gene Pparg is Hira dependent. h3_3_rps19-1 910148 n/a 910165 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false association association false false false Fig 4G. H3.3 enrichment at the active, ribosomal-protein coding gene Rps19 is Hira dependent. h3_3 910149 n/a 910167 unspecified role unspecified role prey prey n/a 910168 unspecified role unspecified role prey prey n/a 910169 unspecified role unspecified role prey prey n/a 910170 unspecified role unspecified role prey prey n/a 910171 unspecified role unspecified role prey prey n/a 910172 unspecified role unspecified role prey prey n/a 910173 unspecified role unspecified role prey prey n/a 910174 unspecified role unspecified role prey prey n/a 910175 unspecified role unspecified role prey prey n/a 910176 unspecified role unspecified role prey prey n/a 910177 unspecified role unspecified role prey prey n/a 910178 unspecified role unspecified role prey prey n/a 910179 unspecified role unspecified role prey prey n/a 910180 unspecified role unspecified role prey prey n/a 910181 unspecified role unspecified role prey prey n/a 910182 unspecified role unspecified role prey prey n/a 910183 unspecified role unspecified role prey prey n/a 910184 unspecified role unspecified role prey prey n/a 910185 unspecified role unspecified role prey prey n/a 910186 unspecified role unspecified role prey prey n/a 910187 unspecified role unspecified role prey prey n/a 910188 unspecified role unspecified role prey prey n/a 910189 unspecified role unspecified role prey prey n/a 910190 unspecified role unspecified role prey prey n/a 910191 unspecified role unspecified role prey prey n/a 910192 unspecified role unspecified role prey prey n/a 910193 unspecified role unspecified role prey prey n/a 910194 unspecified role unspecified role prey prey n/a 910195 unspecified role unspecified role prey prey n/a 910196 unspecified role unspecified role prey prey n/a 910197 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false physical association physical association false false false Fig 6A and Table S4. An interaction between H3.3 and hnRNPG-T and Macf1 was only observed in hira -/- cells. Interactions were not observed in hira -/- cells between H3.3 and (hira), Dnmt3a, Ssrp1, RGS9 and FACTp140. The identification of factors that might mediate specific Hira-independent localization of H3.3 showed that (in addition to Hira), Atrx and Daxx are proteins that specifically associate with H3.3. The participant EBI-2658123(Q9DAE2) was duplicated. It is posssible that originally this interaction did contain more participants pointing to different Trembl proteins which have been merged to a single swissprot protein later. h3_2 910149 n/a 910168 unspecified role unspecified role prey prey n/a 910167 unspecified role unspecified role prey prey n/a 910177 unspecified role unspecified role prey prey n/a 910198 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n/a 910180 unspecified role unspecified role prey prey n/a 910191 unspecified role unspecified role prey prey n/a 910174 unspecified role unspecified role prey prey n/a 910172 unspecified role unspecified role prey prey n/a 910187 unspecified role unspecified role prey prey n/a 910185 unspecified role unspecified role prey prey n/a 910183 unspecified role unspecified role prey prey n/a 910193 unspecified role unspecified role prey prey n/a 910176 unspecified role unspecified role prey prey n/a 910179 unspecified role unspecified role prey prey n/a 910169 unspecified role unspecified role prey prey n/a 910181 unspecified role unspecified role prey prey n/a 910190 unspecified role unspecified role prey prey n/a 910171 unspecified role unspecified role prey prey n/a 910173 unspecified role unspecified role prey prey n/a 910178 unspecified role unspecified role prey prey n/a 910182 unspecified role unspecified role prey prey n/a 910184 unspecified role unspecified role prey prey n/a 910194 unspecified role unspecified role prey prey n/a 910175 unspecified role unspecified role prey prey association association false false false Fig 6A and Table S4. For H3.2 (unlike H3.3), no interactions with hnRNPG-T, Macf1, (hira), Dnmt3a, Ssrp1, RGS9 and FACTp140 were observed in any cell type. h3_1 910149 n/a 910168 unspecified role unspecified role prey prey n/a 910167 unspecified role unspecified role prey prey n/a 910180 unspecified role unspecified role prey prey n/a 910177 unspecified role unspecified role prey prey n/a 910183 unspecified role unspecified role prey prey n/a 910178 unspecified role unspecified role prey prey n/a 910182 unspecified role unspecified role prey prey n/a 910181 unspecified role unspecified role prey prey n/a 910194 unspecified role unspecified role prey prey n/a 910175 unspecified role unspecified role prey prey n/a 910187 unspecified role unspecified role prey prey n/a 910184 unspecified role unspecified role prey prey n/a 910185 unspecified role unspecified role prey prey n/a 910191 unspecified role unspecified role prey prey n/a 910171 unspecified role unspecified role prey prey n/a 910190 unspecified role unspecified role prey prey n/a 910172 unspecified role unspecified role prey prey n/a 910173 unspecified role unspecified role prey prey n/a 910176 unspecified role unspecified role prey prey n/a 910193 unspecified role unspecified role prey prey n/a 910199 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n/a 910174 unspecified role unspecified role prey prey n/a 910179 unspecified role unspecified role prey prey n/a 910169 unspecified role unspecified role prey prey physical association physical association false false false Fig 6A and Table S4. For H3.1 and H3.2 (but unlike H3.3), no interactions with hnRNPG-T, Macf1, (hira), Dnmt3a, Ssrp1, RGS9 and FACTp140 were observed in any cell type. h3_3-1 910150 n/a 910196 unspecified role unspecified role prey prey n/a 910197 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n/a 910188 unspecified role unspecified role prey prey physical association physical association false false false Fig 6B and S6A. Atrx and Daxx association with H3.3 is specific and Hira independent. h3_3-2 910150 n/a 910155 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n/a 910197 unspecified role unspecified role prey prey n/a 910196 unspecified role unspecified role prey prey physical association physical association false false false Fig 6B and S6A. Atrx and Daxx association with H3.3 is specific and Hira independent as Atrx and Daxx associate with H3.3 in Hirs-/- cells. h3_3_egfr 910151 n/a 910200 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false lys4me1 melys methylated lysine MeLys certain certain sequence position certain certain certain sequence position certain false lys36me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain false association association false false false Fig 3B. The Egfr gene is H3K4me3/H3K27me3 bivalent and transcriptionally repressed in ESCs. Upon differentiation to NPCs, H3.3, H3K4me1, and H3K36me3 are enriched in the Egfr gene body. h3_3_ldha 910151 n/a 910155 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false lys4me1 melys methylated lysine MeLys certain certain sequence position certain certain certain sequence position certain false lys36me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain false lys4me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain false n/a 910200 unspecified role unspecified role prey prey association association false false false Fig 3C. H3.3, H3K4me1, and H3K36me3 are enriched in the gene body of the housekeeping gene lactate dehydrogenase A (Ldha) in both ESCs and NPCs and is not enriched in the neighboring Ldhc gene. H3K4me3 is enriched at the Ldha TSS for both ESCs and NPCs. h3_3_human 910152 n/a 910201 unspecified role unspecified role prey prey n/a 910202 unspecified role unspecified role prey prey n/a 910203 unspecified role unspecified role bait bait c terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false c terminus flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false physical association physical association false false false Atrx and Daxx association with H3.3 is specific and Hira independent and conserved in Mouse and Human cells. Fig 6E. h3_3_telomere-1 910153 n/a 910156 unspecified role unspecified role neutral component neutral component n/a 910155 unspecified role unspecified role neutral component neutral component c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false colocalization colocalization false false false Fig 7C. Atrx, but not Hira, is specifically required for H3.3 enrichment at telomeres.H3.3 colocalization with telomeres is lost in Atrxnull ESCs, but maintained in Hira -/- ESCs. h3_3_telomere-3 910154 n/a 910156 unspecified role unspecified role prey prey n/a 910155 unspecified role unspecified role bait bait c terminus yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false lys9me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain false association association false false false Fig S7F. H3.3 associates with telomeres in Atrx-flox and Atrx-null ESCs. ChIP of H3K4me3 and H3K9me3 does not show a significant difference in telomeric enrichment between Atrxflox and Atrxnull ESCs.