UniProt UniProt http://www.uniprot.org xie-2009-5 Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. human-hep_g2 Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt). hep_g2 human hepatocellular carcinoma (HCC) cells (p53-wt). pull down pull down anti tag western anti tag western blot anti tag western Xie Y.B., Park J.H., Kim D.K., Hwang J.H., Oh S., Park S.B., Shong M., Lee I.K., Choi H.S. Apoptosis - Interactions involving proteins with a function related to apoptosis Species origin of used plasmids (SMILE, SIRT1 and ERRgamma) confirmed by authors (e-mail). hsc@chonnam.ac.kr J. Biol. Chem. (0021-9258) 2009 mimix curation xie-2009-1 Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. human-hep_g2 Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt). hep_g2 human hepatocellular carcinoma (HCC) cells (p53-wt). anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Xie Y.B., Park J.H., Kim D.K., Hwang J.H., Oh S., Park S.B., Shong M., Lee I.K., Choi H.S. Apoptosis - Interactions involving proteins with a function related to apoptosis Species origin of used plasmids (SMILE, SIRT1 and ERRgamma) confirmed by authors (e-mail). hsc@chonnam.ac.kr J. Biol. Chem. (0021-9258) 2009 mimix curation xie-2009-4 Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. in vitro In vitro pull down pull down weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Xie Y.B., Park J.H., Kim D.K., Hwang J.H., Oh S., Park S.B., Shong M., Lee I.K., Choi H.S. Apoptosis - Interactions involving proteins with a function related to apoptosis Species origin of used plasmids (SMILE, SIRT1 and ERRgamma) confirmed by authors (e-mail). hsc@chonnam.ac.kr J. Biol. Chem. (0021-9258) 2009 mimix curation xie-2009-2 Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. mouse-liver Mus musculus liver liver anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Xie Y.B., Park J.H., Kim D.K., Hwang J.H., Oh S., Park S.B., Shong M., Lee I.K., Choi H.S. Apoptosis - Interactions involving proteins with a function related to apoptosis Species origin of used plasmids (SMILE, SIRT1 and ERRgamma) confirmed by authors (e-mail). hsc@chonnam.ac.kr J. Biol. Chem. (0021-9258) 2009 mimix curation xie-2009-3 Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. mouse-heart Mus musculus heart [Cardiac; Cardiac tissue] heart Heart [Cardiac; Cardiac tissue] anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Xie Y.B., Park J.H., Kim D.K., Hwang J.H., Oh S., Park S.B., Shong M., Lee I.K., Choi H.S. Apoptosis - Interactions involving proteins with a function related to apoptosis Species origin of used plasmids (SMILE, SIRT1 and ERRgamma) confirmed by authors (e-mail). hsc@chonnam.ac.kr J. Biol. Chem. (0021-9258) 2009 mimix curation xie-2009-6 Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 confocal microscopy confocal microscopy anti tag immunost anti tag immunostaining anti tag immunost Xie Y.B., Park J.H., Kim D.K., Hwang J.H., Oh S., Park S.B., Shong M., Lee I.K., Choi H.S. Apoptosis - Interactions involving proteins with a function related to apoptosis Species origin of used plasmids (SMILE, SIRT1 and ERRgamma) confirmed by authors (e-mail). hsc@chonnam.ac.kr J. Biol. Chem. (0021-9258) 2009 mimix curation xie-2009-7 Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. mouse-kidney Mus musculus kidney kidney [Renal] anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Xie Y.B., Park J.H., Kim D.K., Hwang J.H., Oh S., Park S.B., Shong M., Lee I.K., Choi H.S. Apoptosis - Interactions involving proteins with a function related to apoptosis Species origin of used plasmids (SMILE, SIRT1 and ERRgamma) confirmed by authors (e-mail). hsc@chonnam.ac.kr J. Biol. Chem. (0021-9258) 2009 mimix curation zhang_human CREB/ATF bZIP transcription factor Host cell factor-binding transcription factor Zhangfei CREBZF ZF protein protein human Homo sapiens Human MRHSLTKLLAASGSNSPTRSESPEPAATCSLPSDLTRAAAGEEETAAAGSPGRKQQFGDEGELEAGRGSRGGVAVRAPSPEEMEEEAIASLPGEETEDMDFLSGLELADLLDPRQPDWHLDPGLSSPGPLSSSGGGSDSGGLWRGDDDDEAAAAEMQRFSDLLQRLLNGIGGCSSSSDSGSAEKRRRKSPGGGGGGGSGNDNNQAATKSPRKAAAAAARLNRLKKKEYVMGLESRVRGLAAENQELRAENRELGKRVQALQEESRYLRAVLANETGLARLLSRLSGVGLRLTTSLFRDSPAGDHDYALPVGKQKQDLLEEDDSAGGVCLHVDKDKVSVEFCSACARKASSSLKM err3_mouse Estrogen-related receptor gamma Esrrg Err3 Kiaa0832 Nr3b3 Estrogen receptor-related protein 3 Nuclear receptor subfamily 3 group B member 3 protein protein mouse Mus musculus Mouse MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV sir1_human NAD-dependent protein deacetylase sirtuin-1 NAD-dependent protein deacylase sirtuin-1 SIRT1 SIR2L1 SIR2-like protein 1 Regulatory protein SIR2 homolog 1 protein protein human Homo sapiens Human MADEAALALQPGGSPSAAGADREAASSPAGEPLRKRPRRDGPGLERSPGEPGGAAPEREVPAAARGCPGAAAAALWREAEAEAAAAGGEQEAQATAAAGEGDNGPGLQGPSREPPLADNLYDEDDDDEGEEEEEAAAAAIGYRDNLLFGDEIITNGFHSCESDEEDRASHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAYLSELPPTPLHVSEDSSSPERTSPPDSSVIVTLLDQAAKSNDDLDVSESKGCMEEKPQEVQTSRNVESIAEQMENPDLKNVGSSTGEKNERTSVAGTVRKCWPNRVAKEQISRRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDEPDVPERAGGAGFGTDGDDQEAINEAISVKQEVTDMNYPSNKS err3_human Estrogen-related receptor gamma ESRRG ERR3 ERRG2 KIAA0832 NR3B3 ERR gamma-2 Estrogen receptor-related protein 3 Nuclear receptor subfamily 3 group B member 3 protein protein human Homo sapiens Human MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV zhang_mouse CREB/ATF bZIP transcription factor Crebzf Zf Host cell factor-binding transcription factor Zhangfei Tyrosine kinase-associated leucine zipper protein LAZip protein protein mouse Mus musculus Mouse MRHSLTKLLAASGRDFPSRRDSREPPATRAPPREPSGAAAGAETPRPGSPDREQPHGDGDGGEPEARSGSRGSVAVRAPAPSPLKMEEEEEDAIAMVPKEEPEDMDFLSGLELADLLDPRQPDWHLEPGLSSPGPLSSSGGGSESGGLLRGDDDDDTAAAEMQRFSDLLQRLLNGIGGCSSGGDRGGGEKRRRKSPGAGGGGANDGNQAATKSPRKAAAAAARLNRLKKKEYVMGLESRVRGLAAENQELRAENRELGKRVQALQEESRYLRAVLANETGLARLLSRLSGVGLRLTTSLFRDSPAGDHDYALPVGKQPPEPREEDDAAGGVCLHVDKDKVSVEFCSACARKASSSLKM crebzf-esrrg-5 1242623 n/a 1242630 unspecified role unspecified role bait bait n/a 1242631 unspecified role unspecified role prey prey physical association physical association false false false 3D, 6C crebzf-sirt1-1 1242623 n/a 1242632 unspecified role unspecified role prey prey n/a 1242630 unspecified role unspecified role bait bait physical association physical association false false false 5F crebzf-crebzf 1242623 n/a 1242630 unspecified role unspecified role prey prey n/a 1242630 unspecified role unspecified role bait bait physical association physical association false false false S3B crebzf-esrrg 1242624 n/a 1242630 unspecified role unspecified role bait bait n/a 1242633 unspecified role unspecified role prey prey physical association physical association false false false 1C crebzf-sirt1-2 1242624 n/a 1242632 unspecified role unspecified role prey prey n/a 1242630 unspecified role unspecified role bait bait physical association physical association false false false 5G crebzf-esrrg-3 1242625 n/a 1242631 unspecified role unspecified role prey prey n/a 1242630 unspecified role unspecified role bait bait physical association physical association false false false 1A and 3B crebzf-sirt1 1242625 n/a 1242632 unspecified role unspecified role prey prey n/a 1242630 unspecified role unspecified role bait bait physical association physical association false false false 5E crebzf-esrrg-1 1242626 n/a 1242631 unspecified role unspecified role prey prey n/a 1242634 unspecified role unspecified role bait bait physical association physical association false false false 1C crebzf-esrrg-2 1242627 n/a 1242631 unspecified role unspecified role prey prey n/a 1242634 unspecified role unspecified role bait bait physical association physical association false false false 1C crebzf-esrrg-4 1242628 n/a 1242631 unspecified role unspecified role neutral component neutral component n/a 1242630 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 1D crebzf-esrrg-6 1242629 n/a 1242634 unspecified role unspecified role bait bait n/a 1242631 unspecified role unspecified role prey prey physical association physical association false false false 1C