UniProt UniProt http://www.uniprot.org pai-2004-2 The centrosomal protein CP190 is a component of the gypsy chromatin insulator. yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Pai CY., Lei EP., Ghosh D., Corces VG. Apoptosis - Interactions involving proteins with a function related to apoptosis corces@jhu.edu Mol. Cell (1097-2765) 2004 Chromatin - Epigenetic interactions resulting in chromatin modulation pai-2004-3 The centrosomal protein CP190 is a component of the gypsy chromatin insulator. drome-salivary_gland Drosophila melanogaster Salivary gland salivary_gland Salivary gland fluorescence imaging fluorescence microscopy fluorescence imaging polyclonal immunost polyclonal antibody immunostaining polyclonal immunost Pai CY., Lei EP., Ghosh D., Corces VG. Apoptosis - Interactions involving proteins with a function related to apoptosis corces@jhu.edu Mol. Cell (1097-2765) 2004 Chromatin - Epigenetic interactions resulting in chromatin modulation pai-2004-1 The centrosomal protein CP190 is a component of the gypsy chromatin insulator. drome-embryo drosophilla melanogaster embryo embryo Embryo Defined as the development stage prior to the initiation of tissue differentiation. anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Pai CY., Lei EP., Ghosh D., Corces VG. Apoptosis - Interactions involving proteins with a function related to apoptosis corces@jhu.edu Mol. Cell (1097-2765) 2004 Chromatin - Epigenetic interactions resulting in chromatin modulation pai-2004-4 The centrosomal protein CP190 is a component of the gypsy chromatin insulator. drome-head Drosophila melanogaster head fluorescence imaging fluorescence microscopy fluorescence imaging polyclonal immunost polyclonal antibody immunostaining polyclonal immunost Pai CY., Lei EP., Ghosh D., Corces VG. Apoptosis - Interactions involving proteins with a function related to apoptosis corces@jhu.edu Mol. Cell (1097-2765) 2004 Chromatin - Epigenetic interactions resulting in chromatin modulation pai-2004-5 The centrosomal protein CP190 is a component of the gypsy chromatin insulator. in vitro In vitro emsa supershift electrophoretic mobility supershift assay emsa supershift weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Pai CY., Lei EP., Ghosh D., Corces VG. Apoptosis - Interactions involving proteins with a function related to apoptosis The DNA molecule y454 was radiolabelled with 32P. corces@jhu.edu Mol. Cell (1097-2765) 2004 Chromatin - Epigenetic interactions resulting in chromatin modulation cp190_drome Centrosome-associated zinc finger protein CP190 Cp190 E(mod)4-1 CG6384 dMAP190 Protein enhancer of mod(mdg4)4-1 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MGEVKSVKVDNWGVFFLQKLQNFFNKTDYCDLTLQFRDNSQLKVHRLVLSACTDYFNVLEQTCEIVDDALIMPNEFQADVVVPIVNFMYTGTLEFELKMYGKLLRTAKEMNMTVLLKLLEAHRRTMENVNRQQRPPSPKGIRRRTVGQPSSGLPQQRVLGPSPQSRNVATPIAQRANTQRGSTGNTMSRTSGGSNRSPYGDSSNVKQEPTSPFEQLRKGYNNNKRPAQTSLLSPPSKKPSLEEVKEFAEQQRMRKQIAAEYGDNDPEYDGGMLYDDVHAGDDDDDDMPPQPSTSKQQSPQGTQTQLEHGSTTIILKQDSPSQTPTIIVKDSSNAKLNHTKIIAEVLRQYPHIVKGHKNIKLKIMPNTPAAPTEKSAPATVKPPANQSSATTSPHKKLHVSFKADKSTPLITAQQKAASSQQKSGTSQTTGNQGTGANPPANTAAAQKRRIDSKTMHALIAQGAENTTGPWLCLRCGVNGRPISIPSYRGFRRHLINTHKETIDPALCEHCGWRSVNNRELHFHMYMEHQTKSLLYTFAECALCNQSYRTKGELEAHINEVHTDDNKQQCIYCNKVFEQELQLYRHMKSYHKEQALEDGIIDETDEEFLGSQDEEEEAEGDEEQEPEQTGKVRILSDISLPATSAITVQQAQQEQLQEEDVEQVQQEVKFVGADGNEVELTDEQRKEILSQLNQQQAGATAGGVVMVLSEPEAEHVKQETDEKSLAGTEEEYDDSQIYSELGAADSVESAKKNIADESKESIDNLEWAENLIAESEEQSNKEPKSDKPRDDISEKLKELTGDWTEDENDDDVDDKPATAELASELANKDPEPTVHEEEDDIDLALQSLHKGPEEATEEKASEESVTSADDAVDAVPNINSQPEKMDVDSEAADEKASKAEVQIKKEAELENDQEEFIKEDSPIPHSDSVAELREAVTASEGEDDVHLEADNIRKELLDELIAEAEKPDQEKDIVQSEENATTEALDRSVTDEDDLVPPTQVSTEQMEIDEPAAEKAAENNEDTRTADEKEAVEDKPNQTQDVTTAEKPTLESAKAGDEATSGEAASVDKVKSLISEWGDDDEDEDENGVSAAAKEEL suhw_drome Protein suppressor of hairy wing su(Hw) CG8573 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSASKEGKEKKGKLLGVENISPPKDKRPATRMKLLNDVGAGEDSEASTTTTTSRTPSNKQEKRGSVAGSRIKILNEEILGTPKTEKRGATKSTAPAASTVKILNEKKTPSATVTAVETTKIKTSPSKRKKMEHYVLQAVKSENTKADTTVTVVTEEDDTIDFILADDEEVVPGRIENNNGQEIVVTEDDEDLGEDGDEDGEDSSGKGNSSQTKIKEIVEHVCGKCYKTFRRVQSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFSDFPCSICNANLRSEALLALHEEQHKSRGKPYACKICGKDFTRSYHLKRHQKYSSCSSNETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQAFAVKEVLNRHMKRHTGERPHKCDECGKSFIQATQLRTHSKTHIRPFPCEQCDEKFKTEKQLERHVKTHSRTKRPVFSCAECKRNFRTPALLKEHMDEGKHSPKQQRSSMRSAVKIMERTDCAICDKNFDSSDTLRRHIRTVHECDPDDIFGVEPHPSKRAKKDIESEEVVPVALNTSAGSLISSQTDGNGVVVREFLVDEGDGAAQTITLENETYTILPLDGAIEGEQLTDEAGVKPEAKKEEAQVSPVVKKEQRKSLAASLAAAIADNLEESCSEDDFSGEILTEEDIKLKENVGKLIDMLVDPPILKKYGWPNAPEETVLCKVIENCGHDLTKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDEGGLDKDNESHSGDEEAVSVTGETKTNEIREKPEKKEVSAKSEKKEIVGKAVDKDNSEEVVRENKKKPVGEQEKA q86b87-1 Modifier of mdg4 mod(mdg4) bpd doom E(var)3-93D CG32491 67.2 E(VAR)3-93D protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MADDEQFSLCWNNFNTNLSAGFHESLCRGDLVDVSLAAEGQIVKAHRLVLSVCSPFFRKMFTQMPSNTHAIVFLNNVSHSALKDLIQFMYCGEVNVKQDALPAFISTAESLQIKGLTDNDPAPQPPQESSPPPAAPHVQQQQIPAQRVQRQQPRASARYKIETVDDGLGDEKQSTTQIVIQTTAAPQATIVQQQQPQQAAQQIQSQQLQTGTTTTATLVSTNKRSAQRSSLTPASSSAGVKRSKTSTSANVMDPLDSTTETGATTTAQLVPQQITVQTSVVSAAEAKLHQQSPQQVRQEEAEYIDLPMELPTKSEPDYSEDHGDAAGDAEGTYVEDDTYGDMRYDDSYFTENEDAGNQTAANTSGGGVTATTSKAVVKQQSQNYSESSFVDTSGDQGNTEAQAATSASATKIPPRKRGRPKTKVEDQTPKPKLLEKLQAATLNEEASEPAVYASTTKGGVKLIFNGHLFKFSFRKADYSVFQCCYREHGEECKVRVVCDQKRVFPYEGEHVHFMQASDKSCLPSQFMPGESGVISSLSPSKELLMKNTTKLEEADDKEDEDFEEFEIQEIDEIELDEPEKTPAKEEEVDPNDFREKIKRRLQKALQNKKK C-terminal exons are translated from the opposite DNA strand. This may be due to a trans-splicing event. gaga_drome Transcription factor GAGA Trl GAGA TFGAGA Trithorax-like protein GAGA factor Adh transcription factor 2 Neural conserved at 70F Adf-2 Nc70F CG33261 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MSLPMNSLYSLTWGDYGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLDLLKNTPCKHPVVMLAGVNANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQTVTKDDYTTHSIQLQHMIPQHHDQDQLIATIATAPQQTVHAQVVEDIHHQGQILQATTQTNAAGQQQTIVTTDAAKHDQAVIQAFLPARKRKPRVKKMSPTAPKISKVEGMDTIMGTPTSSHGSGSVQQVLGENGAEGQLLSSTPIIKSEGQKVETIVTMDPNNMIPVTSANAATGEITPAQGATGSSGGNTSGVLSTPKAKRAKHPPGTEKPRSRSQSEQPATCPICYAVIRQSRNLRRHLELRHFAKPGVKKEKKTTSGKKSSSGSSGSGSGALSSSGSVPQVQTVQSLHTLQGVQVKKDPDAQQQQQQQQQQQQQQQQAMTVSGATGGQVQQQVQQVQQQVQQQQQQQQQQQQQLQHHQIIDSSGNITTATTSAQAAAAAQQQAAGQQQQLVAQSDGSESGAPLSIAQVQTLQGHQIIGNLNQVNMTDFQQQQPQQQQQQQQQQQQQQQQQQQTQQTL mmd4_drome Modifier of mdg4 mod(mdg4) bpd doom E(var)3-93D CG32491 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MADDEQFSLCWNNFNTNLSAGFHESLCRGDLVDVSLAAEGQIVKAHRLVLSVCSPFFRKMFTQMPSNTHAIVFLNNVSHSALKDLIQFMYCGEVNVKQDALPAFISTAESLQIKGLTDNDPAPQPPQESSPPPAAPHVQQQQIPAQRVQRQQPRASARYKIETVDDGLGDEKQSTTQIVIQTTAAPQATIVQQQQPQQAAQQIQSQQLQTGTTTTATLVSTNKRSAQRSSLTPASSSAGVKRSKTSTSANVMDPLDSTTETGATTTAQLVPQQITVQTSVVSAAEAKLHQQSPQQVRQEEAEYIDLPMELPTKSEPDYSEDHGDAAGDAEGTYVEDDTYGDMRYDDSYFTENEDAGNQTAANTSGGGVTATTSKAVVKQQSQNYSESSFVDTSGDQGNTEAQAATSASATKIPPRKRGRPKTKVEDQTPKPKLLEKLQAATLNEEASEPAVYASTTKGGVKLIFNGHLFKFSFRKADYSVFQCCYREHGEECKVRVVCDQKRVFPYEGEHVHFMQASDKSCLPSQFMPGESGVISSLSPSKELLMKNTTKLEEADDKEDEDFEEFEIQEIDEIELDEPEKTPAKEEEVDPNDFREKIKRRLQKALQNKKK y_drome_y454 Drosophila melanogaster 454 bp regulatory fragment from the yellow gene dna deoxyribonucleic acid DNA deoxyribonucleic acid dna DNA deoxyribonucleic acid in vitro In vitro GGAGTACTACTACCAGGCAAGAAAGTAGGTTGATAAAGCTATGCACAAGATCTGTCATATGGATGGGTTTCGCATCTTCTGGATCATAGGACTTGAGAACATACACAAACACAACTAAAATCAGAAAAGGTTGCCAGCAAACACTTTAGTTTTCTGCAAGCTAGATCCACCTGCTACTATCCCTACTTTCTTCTGTTGGGGTTGTCAGAGCTCTACCTACAGTTGATTAAACCACACATCAGTCATCGTGTTTTTTTTACAATTTTCCTAATTTCCTTACTTGTATTGCCTACTTTTTTGCGAGGGACTTCTATTGGCCAGTATATATTATGTGTTGCATACTCTTGGTCACAGCAAAAATAAAACAAAAAATACGCATGGTAAAAGAATGCTTCCTTTTTTACGCACAACGGTAGACGAAGCATATAATTTTTACATATCGGAAATGTTCTTG cp190-suhw-2 669965 N/A 669970 unspecified role unspecified role bait bait N/A 669971 unspecified role unspecified role prey prey physical association physical association false false false 4B cp190-mod_mdg4-1 669965 N/A 669972 unspecified role unspecified role prey prey N/A 669970 unspecified role unspecified role bait bait physical association physical association false false false 4B mod_mdg4-cp190-1 669965 N/A 669972 unspecified role unspecified role bait bait N/A 669970 unspecified role unspecified role prey prey physical association physical association false false false 4B suhw-mod_mdg4-1 669965 N/A 669972 unspecified role unspecified role prey prey N/A 669971 unspecified role unspecified role bait bait physical association physical association false false false 4B mod_mdg4-trl-1 669965 N/A 669973 unspecified role unspecified role prey prey N/A 669972 unspecified role unspecified role bait bait physical association physical association false false false 4B cp190-mod_mdg4-2 669966 N/A 669972 unspecified role unspecified role neutral component neutral component N/A 669970 unspecified role unspecified role neutral component neutral component physical association physical association false false false 3A, 3B, 3C cp190-suhw-3 669966 N/A 669971 unspecified role unspecified role neutral component neutral component N/A 669970 unspecified role unspecified role neutral component neutral component physical association physical association false false false 3B, 5A suhw-mod_mdg4-3 669966 N/A 669971 unspecified role unspecified role neutral component neutral component N/A 669972 unspecified role unspecified role neutral component neutral component physical association physical association false false false 5A cp190-suhw-1 669967 N/A 669970 unspecified role unspecified role bait bait N/A 669971 unspecified role unspecified role prey prey N/A 669974 unspecified role unspecified role prey prey association association false false false 4A cp190-mod_mdg4-3 669968 N/A 669972 unspecified role unspecified role neutral component neutral component N/A 669970 unspecified role unspecified role neutral component neutral component physical association physical association false false false 5B cp190-suhw-4 669969 N/A 669975 unspecified role unspecified role bait bait N/A 669971 unspecified role unspecified role prey prey in vitro In vitro N/A 669970 unspecified role unspecified role prey prey in vitro In vitro association association false false false 4E