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    <entry>
        <source releaseDate="2014-12-22Z">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
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                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
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                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
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                <attribute name="url">http://www.ebi.ac.uk/</attribute>
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        </source>
        <experimentList>
            <experimentDescription id="1766574">
                <names>
                    <shortLabel>adebiyi-2014-1</shortLabel>
                    <fullName>Lipid rafts are required for signal transduction by angiotensin II receptor type 1 in neonatal glomerular mesangial cells.</fullName>
                </names>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9823">
                        <names>
                            <shortLabel>pig-kidney-mesangial_cell</shortLabel>
                            <fullName>Sus scrofa kidney-mesangial_cell</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>kidney-mesangial_cell</shortLabel>
                                <fullName>mesangial cells</fullName>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>confocal microscopy</shortLabel>
                        <fullName>confocal microscopy</fullName>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>immunocytochemistry</shortLabel>
                        <fullName>immunocytochemistry</fullName>
                    </names>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Adebiyi A., Soni H., John T.A., Yang F.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Affinomics - Interactions curated for the Affinomics consortium.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">neonatal   glomerular mesangial cells</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">aadebiyi@uthsc.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Exp. Cell Res. (0014-4827)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2014</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="1766575">
                <names>
                    <shortLabel>adebiyi-2014-2</shortLabel>
                    <fullName>Lipid rafts are required for signal transduction by angiotensin II receptor type 1 in neonatal glomerular mesangial cells.</fullName>
                </names>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9823">
                        <names>
                            <shortLabel>pig-kidney-mesangial_cell</shortLabel>
                            <fullName>Sus scrofa kidney-mesangial_cell</fullName>
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                        <tissue>
                            <names>
                                <shortLabel>kidney-mesangial_cell</shortLabel>
                                <fullName>mesangial cells</fullName>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>pla</shortLabel>
                        <fullName>proximity ligation assay</fullName>
                        <alias typeAc="MI:0303" type="go synonym">pELISA</alias>
                        <alias typeAc="MI:1041" type="synonym">pELISA</alias>
                        <alias typeAc="MI:1041" type="synonym">PLA</alias>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>antibody detection</shortLabel>
                        <fullName>identification by antibody</fullName>
                        <alias typeAc="MI:1041" type="synonym">antibody detection</alias>
                    </names>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Adebiyi A., Soni H., John T.A., Yang F.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Affinomics - Interactions curated for the Affinomics consortium.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">neonatal   glomerular mesangial cells</attribute>
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                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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        </experimentList>
        <interactorList>
            <interactor id="1766576">
                <names>
                    <shortLabel>cav1_pig</shortLabel>
                    <fullName>Caveolin-1</fullName>
                    <alias typeAc="MI:0301" type="gene name">CAV1</alias>
                </names>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                        <shortLabel>pig</shortLabel>
                        <fullName>Sus scrofa (Pig)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Pig</alias>
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                <sequence>MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMAEEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNIRINMQKEI</sequence>
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            <interactor id="1766577">
                <names>
                    <shortLabel>agtr1_pig</shortLabel>
                    <fullName>Type-1 angiotensin II receptor</fullName>
                    <alias typeAc="MI:0301" type="gene name">AGTR1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Angiotensin II type-1 receptor</alias>
                </names>
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                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSSSCT00000034453" version="SP_140" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSSSCT00030061647" version="SP_140" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSSSCP00015028872" version="SP_140" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSSSCG00060063200" version="SP_140" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSSSCT00060086211" version="SP_140" refType="transcript"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9823">
                    <names>
                        <shortLabel>pig</shortLabel>
                        <fullName>Sus scrofa (Pig)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Pig</alias>
                    </names>
                </organism>
                <sequence>MILNSSTEDSIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKIADIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSENGSSSTKKSAPCTEVE</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-23562-1" id="1766578">
                <names>
                    <shortLabel>agtr1-cav1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10042396" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" refType="component" refTypeAc="MI:0354"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23562-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1766574</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1766579">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10042520" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1766576</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1766580">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10042519" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1766577</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">6C</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-23562-2" id="1766581">
                <names>
                    <shortLabel>agtr1-cav1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10042531" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23562-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1766575</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1766582">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10042535" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1766576</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1766583">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10042534" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1766577</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>proximity</shortLabel>
                        <fullName>proximity</fullName>
                        <alias typeAc="MI:1041" type="synonym">close-contact colocalization</alias>
                        <alias typeAc="MI:1041" type="synonym">neighbourhood interaction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">6D</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
