IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ kern-2013-1 Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress. in vitro In vitro pull down pull down sequence tag sequence tag identification sequence tag Kern F., Stanika R.I., Sarg B., Offterdinger M., Hess D., Obermair G.J., Lindner H., Bandtlow C.E., Hengst L., Schweigreiter R. Affinomics - Interactions curated for the Affinomics consortium. Column eluates were either briefly run via SDS/PAGE followed by LC-MS/MS, or were TCA-precipitated and then analysed by LC-MS/MS. The protein (genbank ID) EDL09793.1. has a different N-terminal sequence from any protein currently in UniProt. ruediger.schweigreiter@i-med.ac.at Biochem. J. (0264-6021) 2013 Only protein-protein interactions imex curation kern-2013-3 Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress. crigr-cho_k1 Cricetulus griseus ovary K1 cho_k1 Chinese Hamster Ovary K1 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kern F., Stanika R.I., Sarg B., Offterdinger M., Hess D., Obermair G.J., Lindner H., Bandtlow C.E., Hengst L., Schweigreiter R. Affinomics - Interactions curated for the Affinomics consortium. ruediger.schweigreiter@i-med.ac.at Biochem. J. (0264-6021) 2013 Only protein-protein interactions imex curation kern-2013-4 Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress. mouse-brain Mus musculus brain brain Brain [cerebrum] anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kern F., Stanika R.I., Sarg B., Offterdinger M., Hess D., Obermair G.J., Lindner H., Bandtlow C.E., Hengst L., Schweigreiter R. Affinomics - Interactions curated for the Affinomics consortium. ruediger.schweigreiter@i-med.ac.at Biochem. J. (0264-6021) 2013 Only protein-protein interactions imex curation kern-2013-2 Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress. in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Kern F., Stanika R.I., Sarg B., Offterdinger M., Hess D., Obermair G.J., Lindner H., Bandtlow C.E., Hengst L., Schweigreiter R. Affinomics - Interactions curated for the Affinomics consortium. ruediger.schweigreiter@i-med.ac.at Biochem. J. (0264-6021) 2013 Only protein-protein interactions imex curation kern-2013-5 Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress. mouse-brain_hippocampal_neuron Mus musculus, brain, hippocampal neurons brain-hippocampus_neuron Hippocampal neuron confocal microscopy confocal microscopy immunocytochemistry immunocytochemistry Kern F., Stanika R.I., Sarg B., Offterdinger M., Hess D., Obermair G.J., Lindner H., Bandtlow C.E., Hengst L., Schweigreiter R. Affinomics - Interactions curated for the Affinomics consortium. ruediger.schweigreiter@i-med.ac.at Biochem. J. (0264-6021) 2013 Only protein-protein interactions imex curation kern-2013-6 Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress. crigr-cho_k1 Cricetulus griseus ovary K1 cho_k1 Chinese Hamster Ovary K1 pla proximity ligation assay pELISA pELISA PLA antibody detection identification by antibody antibody detection Kern F., Stanika R.I., Sarg B., Offterdinger M., Hess D., Obermair G.J., Lindner H., Bandtlow C.E., Hengst L., Schweigreiter R. Affinomics - Interactions curated for the Affinomics consortium. ruediger.schweigreiter@i-med.ac.at Biochem. J. (0264-6021) 2013 Only protein-protein interactions imex curation kern-2013-7 Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress. mouse-brain_hippocampal_neuron Mus musculus, brain, hippocampal neurons brain-hippocampus_neuron Hippocampal neuron pla proximity ligation assay pELISA pELISA PLA antibody detection identification by antibody antibody detection Kern F., Stanika R.I., Sarg B., Offterdinger M., Hess D., Obermair G.J., Lindner H., Bandtlow C.E., Hengst L., Schweigreiter R. Affinomics - Interactions curated for the Affinomics consortium. ruediger.schweigreiter@i-med.ac.at Biochem. J. (0264-6021) 2013 Only protein-protein interactions imex curation hs74l_mouse Heat shock 70 kDa protein 4L Hspa4l Apg1 Hsp4l Osp94 Osmotic stress protein 94 Heat shock 70-related protein APG-1 protein protein mouse Mus musculus Mouse MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSTGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSVTLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAAMETEAPKSEGKEDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKAKAPPSDKQDRINQTIKKGKIKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAMLEDTENWLYEEGEDQPKQVYVDRLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMERVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVTKSKELDNFCNPIVYKPKPKVEAPEDKAKTGSEHNGPMDGQSGSETSPDPPKGSSQHTDSGEMEVD mint Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase prdx5_mouse Peroxiredoxin-5, mitochondrial Prdx5 Prdx6 Peroxiredoxin V Peroxisomal antioxidant enzyme PLP Thioredoxin peroxidase PMP20 Antioxidant enzyme B166 Liver tissue 2D-page spot 2D-0014IV Thioredoxin-dependent peroxiredoxin 5 protein protein mouse Mus musculus Mouse MLQLGLRVLGCKASSVLRASTCLAGRAGRKEAGWECGGARSFSSSAVTMAPIKVGDAIPSVEVFEGEPGKKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAGALKAKGAQVVACLSVNDVFVIEEWGRAHQAEGKVRLLADPTGAFGKATDLLLDDSLVSLFGNRRLKRFSMVIDNGIVKALNVEPDGTGLTCSLAPNILSQL prdx2_mouse Peroxiredoxin-2 Thioredoxin-dependent peroxiredoxin 2 Thioredoxin peroxidase 1 Thioredoxin-dependent peroxide reductase 1 Thiol-specific antioxidant protein Prdx2 Tdpx1 Tpx protein protein mouse Mus musculus Mouse MASGNAQIGKSAPDFTATAVVDGAFKEIKLSDYRGKYVVLFFYPLDFTFVCPTEIIAFSDHAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTKSLSQNYGVLKNDEGIAYRGLFIIDAKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN prdx1_mouse Peroxiredoxin-1 Thioredoxin-dependent peroxiredoxin 1 Thioredoxin-dependent peroxide reductase 2 Osteoblast-specific factor 3 Macrophage 23 kDa stress protein Thioredoxin peroxidase 2 Prdx1 Msp23 Paga Tdpx2 protein protein mouse Mus musculus Mouse MSSGNAKIGYPAPNFKATAVMPDGQFKDISLSEYKGKYVVFFFYPLDFTFVCPTEIIAFSDRADEFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITINDLPVGRSVDEIIRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVNKSKEYFSKQK q9jk11-1 Reticulon-4 Nogo-A NI-220-250 Rtn4 Nogo Foocen Glut4 vesicle 20 kDa protein Neurite outgrowth inhibitor protein protein rat Rattus norvegicus (Rat) Rat MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPAAAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAPAPSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAEKIMDLMEQPGNTVSSGQEDFPSVLLETAASLPSLSPLSTVSFKEHGYLGNLSAVSSSEGTIEETLNEASKELPERATNPFVNRDLAEFSELEYSEMGSSFKGSPKGESAILVENTKEEVIVRSKDKEDLVCSAALHSPQESPVGKEDRVVSPEKTMDIFNEMQMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAARANVESKVDRKCLEDSLEQKSLGKDSEGRNEDASFPSTPEPVKDSSRAYITCASFTSATESTTANTFPLLEDHTSENKTDEKKIEERKAQIITEKTSPKTSNPFLVAVQDSEADYVTTDTLSKVTEAAVSNMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESLYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSAGASVVQPSVSPLEAPPPVSYDSIKLEPENPPPYEEAMNVALKALGTKEGIKEPESFNAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKSVPEHAELVEDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVSETVAQHKEERLSASPQELGKPYLESFQPNLHSTKDAASNDIPTLTKKEKISLQMEEFNTAIYSNDDLLSSKEDKIKESETFSDSSPIEIIDEFPTFVSAKDDSPKLAKEYTDLEVSDKSEIANIQSGADSLPCLELPCDLSFKNIYPKDEVHVSDEFSENRSSVSKASISPSNVSALEPQTEMGSIVKSKSLTKEAEKKLPSDTEKEDRSLSAVLSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD pp1r7_mouse Protein phosphatase 1 regulatory subunit 7 Ppp1r7 Sds22 Protein phosphatase 1 regulatory subunit 22 protein protein mouse Mus musculus Mouse MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHGGGGIVANLSEQSLKDGVDRGAEDPEEEHELAVDMETINLDRDAEDVDLTHYRIGKIEGLEVLKKVKSLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEVLDISFNMLRNIEGIDKLTQLKKLFLVNNKINKIENISNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATYVRF mint Regulatory subunit of protein phosphatase 1 caza2_mouse F-actin-capping protein subunit alpha-2 Capza2 Cappa2 CapZ alpha-2 protein protein mouse Mus musculus Mouse MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPYEAENAIESWRTSVETALRAYVKEHYPNGVCTVYGKKVDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTVTPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA clh1_mouse Clathrin heavy chain 1 Cltc protein protein mouse Mus musculus Mouse MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDEEPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAILGNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDRFDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEVVQAANASGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMNHPTDAWKEGQFKDIITKVANVELYYKAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLRKEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQPGFGYSM prdx4_mouse Peroxiredoxin-4 Peroxiredoxin IV Thioredoxin peroxidase AO372 Thioredoxin-dependent peroxide reductase A0372 Antioxidant enzyme AOE372 Thioredoxin-dependent peroxiredoxin 4 Prdx4 protein protein mouse Mus musculus Mouse MEARSKLLDGTTASRRWTRKLVLLLPPLLLFLLRTESLQGLESDERFRTRENECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN camk2a calcium/calmodulin-dependent protein kinase II alpha, isoform CRA_a, partial protein protein mouse Mus musculus Mouse MDMHLCAHVSLSPRGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRV q8bz98-2 Dynamin-3 Dnm3 Kiaa0820 protein protein mouse Mus musculus Mouse MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRHEIEAETDRVTGMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIRDMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEAFKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVMQELINTVKKCTKRLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKSTIGNQVIRKGWLTVSNIGIMKGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKGFMSSKHVFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPDKSVTENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALAIIGDINTATVSTPAPPPVDDSWLQHSRRSPPPSPTTQRRLTISAPLPRPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPNSSDSFGAPPQVPSRPTRAPPSVPSRRPPPSPTRPTIIRPLESSLLD No experimental confirmation available. rtn4_mouse Reticulon-4 Rtn4 Kiaa0886 Nogo Neurite outgrowth inhibitor protein protein mouse Mus musculus Mouse MEDIDQSSLVSSSADSPPRPPPAFKYQFVTEPEDEEDEEDEEEEEDDEDLEELEVLERKPAAGLSAAPVPPAAAPLLDFSSDSVPPAPRGPLPAAPPTAPERQPSWERSPAASAPSLPPAAAVLPSKLPEDDEPPARPPAPAGASPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAEKIMDLKEQPGNTVSSGQEDFPSVLFETAASLPSLSPLSTVSFKEHGYLGNLSAVASTEGTIEETLNEASRELPERATNPFVNRESAEFSVLEYSEMGSSFNGSPKGESAMLVENTKEEVIVRSKDKEDLVCSAALHNPQESPATLTKVVKEDGVMSPEKTMDIFNEMKMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAARANMESKVDKKCFEDSLEQKGHGKDSESRNENASFPRTPELVKDGSRAYITCDSFSSATESTAANIFPVLEDHTSENKTDEKKIEERKAQIITEKTSPKTSNPFLVAIHDSEADYVTTDNLSKVTEAVVATMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESIYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSTGASVAQPSASPLEVPSPVSYDGIKLEPENPPPYEEAMSVALKTSDSKEEIKEPESFNAAAQEAEAPYISIACDLIKETKLSTEPSPEFSNYSEIAKFEKSVPDHCELVDDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVSETVTQHKHKERLSASPQEVGKPYLESFQPNLHITKDAASNEIPTLTKKETISLQMEEFNTAIYSNDDLLSSKEDKMKESETFSDSSPIEIIDEFPTFVSAKDDSPKEYTDLEVSNKSEIANVQSGANSLPCSELPCDLSFKNTYPKDEAHVSDEFSKSRSSVSKVPLLLPNVSALESQIEMGNIVKPKVLTKEAEEKLPSDTEKEDRSLTAVLSAELNKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQAQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAE rtn4-hspa4l-3 1567381 n/a 1567388 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567389 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567390 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567391 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567392 unspecified role unspecified role bait bait nig_domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false c_terminus strep tag strep tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false crigr-cho_k1 Cricetulus griseus ovary K1 cho_k1 Chinese Hamster Ovary K1 association association false false false Fig 1C, Supp table 1 TCA precipitation was used prior to MS/MS. All proteins listed were identified in two independent MS screens. rtn4-camk2a-6 1567381 n/a 1567393 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567388 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567394 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567395 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567392 unspecified role unspecified role bait bait c_terminus strep tag strep tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false nig_domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false crigr-cho_k1 Cricetulus griseus ovary K1 cho_k1 Chinese Hamster Ovary K1 n/a 1567396 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567391 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567397 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567398 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] association association false false false 1C, Supp table 1 SDS/PAGE, followed by in-gel digestion was used prior to MS/MS rtn4-hspa4l-5 1567382 n/a 1567388 unspecified role unspecified role prey prey n/a 1567392 unspecified role unspecified role bait bait physical association physical association false false false Fig 1E hspa4l-rtn4 1567382 n/a 1567388 unspecified role unspecified role bait bait n/a 1567392 unspecified role unspecified role prey prey physical association physical association false false false Fig 1E hspa4l-rtn4-1 1567383 n/a 1567388 unspecified role unspecified role bait bait n/a 1567399 unspecified role unspecified role prey prey physical association physical association false false false Fig 2A rtn4-hspa4l-6 1567383 n/a 1567388 unspecified role unspecified role prey prey n/a 1567399 unspecified role unspecified role bait bait physical association physical association false false false Fig 2A rtn4-hspa4l-4 1567384 n/a 1567388 unspecified role unspecified role prey prey mouse-brain Mus musculus brain brain Brain [cerebrum] n/a 1567392 unspecified role unspecified role bait bait nig_domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false c_terminus strep tag strep tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false crigr-cho_k1 Cricetulus griseus ovary K1 cho_k1 Chinese Hamster Ovary K1 physical association physical association false false false Fig 1D very faint band visible hspa4l-rtn4-4 1567385 n/a 1567388 unspecified role unspecified role neutral component neutral component n/a 1567399 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Supp Fig 1 hspa4l-rtn4-3 1567386 n/a 1567388 unspecified role unspecified role neutral component neutral component nls_from_sv40_large-t-antigen tag tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false e_blue_fluorescent_protein fluorescent prot tag fluorescent protein tag fluorescent prot tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n/a 1567392 unspecified role unspecified role neutral component neutral component c_terminus egfp tag enhanced green fluorescent protein tag enhanced green fluorescent protein EGFP enhanced green fluorescent protein EGFP egfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false proximity proximity close-contact colocalization neighbourhood interaction false false false Fig 4A hspa4l-rtn4-5 1567387 n/a 1567388 unspecified role unspecified role neutral component neutral component n/a 1567399 unspecified role unspecified role neutral component neutral component proximity proximity close-contact colocalization neighbourhood interaction false false false Fig 4B