IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ ito-2013-1 Close Association of Carbonic Anhydrase (CA2a and CA15a), Na(+)/H(+) Exchanger (Nhe3b), and Ammonia Transporter Rhcg1 in Zebrafish Ionocytes Responsible for Na(+) Uptake. danre-gill Zebrafish Gill gill GILL pla proximity ligation assay pELISA pELISA PLA antibody detection identification by antibody antibody detection Ito Y., Kobayashi S., Nakamura N., Miyagi H., Esaki M., Hoshijima K., Hirose S. Affinomics - Interactions curated for the Affinomics consortium. signals were detected on gill sections at inter-lamellar regions predominantly at the bases of the lamellae. Identifiers for zebrafish proteins were obtained from Table1 and ZFin Database. CA15A was identified from the sequence given under "plasmid construction" and from the relevant antibody immungen sequence; the longest sequence found in UniProt was taken. pj.ca.hcetit.oib@esorihs Front Physiol 2013 imex curation Only protein-protein interactions a9xp97_danre Sodium/hydrogen exchanger slc9a3.2 NHE3b protein protein danre Danio rerio (Zebrafish) Brachydanio rerio Zebrafish MAFSTLLLAFLVVSGALHEAAAGLDFYGAEGKQNYSSRSSAEGSASSGNSSHSATITTLPIVTWKWHHVETPYLVALWILTCWICKLVTELNHNITSVIPESGLLIILGFILGGIVWGADKAQTFKLIPVNFFFYLLPQIILDASYCMPNKLFFGNLGAILVHAIIGTCWNAGTVGIALWACYEGGAMGTLNIGCLQFLLFGALMSAVDPVAVIAVFEEVHVNEVLYILVFGESLLNDGVTVVLYNVFDAFVSLGGPKINAAEIIKGIVSFAVVAFGGSFLGVVFAVLTSMLTRVTKNVQIIEAGFIIVLGYLSYLTAEMLSLSAILSLTFCGVCCQKYINANMDEKSVTCLRYSLKVLANGSETMIFVFLGVSAIDQTIWVWNTGFILLTLLFIVVFRMMGVFFLNWILNQSRLIPIDLTDQLVMGYGGLRGAVAYGLAASLDENKIPEKNLMLGTTLIVVYFTVILQGITMKPLVNWLKVKKATQSDLTLNGKLNNRVFEHTLTGMEDICGRMGDNWWTRHWNHFEEKYVCWLLMTSEARKRNDKILDAFHKLNVEDATKYVNEGESKGSLAFIRSYDSASVDFKKKLALEYADIIPDIMADMSEYDFDIDSVPVTSVMKNPIPSVSLDIHEQERRGMSNDLNAHHLLEQHLYKSRRNNRATYSRSHYNTSENPDEMQEIFQRTMGNRLESFKSAKMGVNPAKKVSKHPKKDAPHKPNGKPADPNRDHLYGDEDFEFSADSASSSENTCQFPRRVINTTGAGVDNPAYIPELDTSPSMRNPPWQTETGHNTAVAPSQRAQGRLPWTPTNLRRLAPLRVSSRSTDSFAMPEPAADEETPEEKPATHHTRL q6pfu7_danre Carbonic anhydrase ca2 protein protein danre Danio rerio (Zebrafish) Brachydanio rerio Zebrafish MADHWGYDKHNGPDKWGESYPIANGSRQSPIDIKSSTTTYDEKLTPLKLKYDPSTSLDIQNNGHSFQVSFVDDQNSSTLTGGPVTGTFRLKQFHFHWGSADDKGSEHTVNGKCYPAELHLVHWNTKYPSFKDAVDKPDGLAVVGIFLKIGADNPKLQKILDAMDAIKSKGKQTPFPNFDPSVLLPSSLDYWTYLGSLTTPPLLESVTWIVCKQSISVSSAQMKRFRSLLFSGDGEKACCMVNNYRPPQPLKGRVVRASFK q502e2_danre Carbonic anhydrase ca15a protein protein danre Danio rerio (Zebrafish) Brachydanio rerio Zebrafish NSADRLEKQVEEMIAFLISFLAALLCESVHSDNSAVAWCYNNPLCNFTTWPELSPHYCNGSSQSPINIVTAQVLENSNLTQFNFTGFDANTTFISMANSGISVVVTLDEEIMSVQGGDLPGLYISKQFHLHWGNSSSFPGSEHTVDGKQYAMELHIVNVHSKYNGSLSAALAANDSSALAVLGFFIEGTNEASKAKGWGVLTSFLRNITYSGNATVDIMNQTSMNSLLEGVNKTKYYRYRGSLTTPSCNEAVIWTVFKEPIKVSNNLINLFSTAVFTKNASAPVLNVNNFRGVQPLNGRVVTSQVEQTASPTAPSSAATSISSLSLLLLLTSLCCL rhcl2_danre Ammonium transporter Rh type C-like 2 rhcgl2 rhcg rhcg1 Rhesus blood group family type C glycoprotein-like 2 drRhcg1 zgc:77520 protein protein danre Danio rerio (Zebrafish) Brachydanio rerio Zebrafish MGNCFGSRGICDRPKNTNIRLSLPAVCFVWQVSMIILFGVFVRYNEEADTNWVYTKKEKNITSDIENDFYFRYPSFQDVHVMIFVGFGFLMTFLKRYSFGAVGFNFLIAAFGLQWALLMQGWFSPLGDDGKIKIGIENLINADFCVASCLIAYGAVLGKVSPVQLLVMTLFGITLYAVEEFIILRVLNAKDAGGSMVIHTFGAYYGLSISRVLYRPNLNKSKHMNGSVYHSDVFAMIGTLFLWMFWPSFNSAICNHGDGQHRAAINTYLALASTVLTTVAISSMFEKTGKLDMVHIQNSTLAGGVAVGTAAEFMLMPYGSLIVGFFCGIISTLGYIYLTPFLEERLKIQDTCGIHNLHAMPGVIGGIVGAISAAAASKEVYGDLGLKNIFSIEGSNVTRLPTVQGGYQAAALCVALCFGIGGGTFVGLVLKLPIWGDPADEHCFNDEMYWEVPEDEESIIPPVLSYNNHMIPNNKHEEMRETNFAEQS ca2-slc9a3_2 1547454 n/a 1547455 unspecified role unspecified role neutral component neutral component n/a 1547456 unspecified role unspecified role neutral component neutral component proximity proximity close-contact colocalization neighbourhood interaction false false false 6A ca2-slc9a3_2-1 1547454 n/a 1547455 unspecified role unspecified role neutral component neutral component n/a 1547457 unspecified role unspecified role neutral component neutral component proximity proximity close-contact colocalization neighbourhood interaction false false false 6B ca2-slc9a3_2-2 1547454 n/a 1547458 unspecified role unspecified role neutral component neutral component n/a 1547455 unspecified role unspecified role neutral component neutral component proximity proximity close-contact colocalization neighbourhood interaction false false false 6C