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                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
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                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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                <attribute name="url">http://www.ebi.ac.uk/</attribute>
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                <names>
                    <shortLabel>chaudhury-2012-1</shortLabel>
                    <fullName>Role of myosin Va in purinergic vesicular neurotransmission in the gut.</fullName>
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                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-neuron</shortLabel>
                            <fullName>Mus musculus neuronal cell</fullName>
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                        <tissue>
                            <names>
                                <shortLabel>neuron</shortLabel>
                                <fullName>Neuron [Neuronal cell; Neural cell</fullName>
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                    <names>
                        <shortLabel>confocal microscopy</shortLabel>
                        <fullName>confocal microscopy</fullName>
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                    <names>
                        <shortLabel>immunostaining</shortLabel>
                        <fullName>immunostaining</fullName>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Chaudhury A., He X.D., Goyal R.K.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Affinomics - Interactions curated for the Affinomics consortium.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">The experiment was performed using varicosities, bulbous nerve endings of neurons obtained from the subdiaphragmatic portion of gut.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">raj_goyal@hms.harvard.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Am. J. Physiol. Gastrointest. Liver Physiol. (0193-1857)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
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                <names>
                    <shortLabel>chaudhury-2012-2</shortLabel>
                    <fullName>Role of myosin Va in purinergic vesicular neurotransmission in the gut.</fullName>
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                            <shortLabel>mouse-neuron</shortLabel>
                            <fullName>Mus musculus neuronal cell</fullName>
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                                <shortLabel>neuron</shortLabel>
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                        <shortLabel>pla</shortLabel>
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                    <names>
                        <shortLabel>antibody detection</shortLabel>
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                    <attribute name="exp-modification" nameAc="MI:0627">The experiment was performed using varicosities, bulbous nerve endings of neurons obtained from the subdiaphragmatic portion of gut.</attribute>
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                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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            <interactor id="1434729">
                <names>
                    <shortLabel>s17a9_mouse</shortLabel>
                    <fullName>Solute carrier family 17 member 9</fullName>
                    <alias typeAc="MI:0301" type="gene name">Slc17a9</alias>
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                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
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                <sequence>MPSQRSSLMQPIPEETRKTPSAAAEDTRWSRPECQAWTGILLLGTCLLYCARVTMPVCTVAMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGFITVTTPLLAHLGSGHLAFLTFSRILTGLLQGVYFPALTSLLSQKVQESERAFTYSTVGAGSQVGTLVTGGVGSVLLDQCGWQSVFYFSGGLTLLWAYYVYRYLLNEKDLVLALGFLAQGLPVTKPSKVPWRQLFRKASVWAAICSQLCSACSFFILLSWLPTFFKETFPNSKGWVFNVVPWMLAIPASLFSGFISDRLISQGYRVITVRKFMQVMGLGLSSIFALCLGHTTSFLKAMIFASASIGFQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLSGYLIETTGSWTCVFHLVAIISNLGLGTFLVFGKAQRVDLVPTHEDL</sequence>
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            <interactor id="1434730">
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                    <shortLabel>myo5a_mouse</shortLabel>
                    <fullName>Unconventional myosin-Va</fullName>
                    <alias typeAc="MI:0301" type="gene name">Myo5a</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Dilute</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Dilute myosin heavy chain, non-muscle</alias>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002710" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904960" secondary="positive regulation of cytochrome-c oxidase activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031585" secondary="regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016459" secondary="myosin complex" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051643" secondary="endoplasmic reticulum localization" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016192" secondary="vesicle-mediated transport" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032869" secondary="cellular response to insulin stimulus" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005790" secondary="smooth endoplasmic reticulum" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904754" secondary="positive regulation of vascular associated smooth muscle cell migration" version="SP_195"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q99104" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098794" secondary="postsynapse" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048306" secondary="calcium-dependent protein binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043008" secondary="ATP-dependent protein binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031987" secondary="locomotion involved in locomotory behavior" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030048" secondary="actin filament-based movement" version="SP_195"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E9PUE5" version="SP_106" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003774" secondary="motor activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031982" secondary="vesicle" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0099089" secondary="establishment of endoplasmic reticulum localization to postsynapse" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042642" secondary="actomyosin, myosin complex part" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005882" secondary="intermediate filament" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900078" secondary="positive regulation of cellular response to insulin stimulus" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0065003" secondary="protein-containing complex assembly" version="SP_195"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000116028" version="SP_195" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0099640" secondary="axo-dendritic protein transport" version="SP_195"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027417" version="SP_195"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001609" version="SP_195"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_034994.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030073" secondary="insulin secretion" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030050" secondary="vesicle transport along actin filament" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072659" secondary="protein localization to plasma membrane" version="SP_195"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLGDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPIEKKVPLDMSLFLKLQKRVTELEQEKQLMQDELDRKEEQVFRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKREDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIARV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-21250-1" id="1434731">
                <names>
                    <shortLabel>myo5a-slc17a9</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6931600" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21250-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1434727</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1434732">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6931619" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1434729</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1434733">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6931618" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1434730</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">6a</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-21250-2" id="1434734">
                <names>
                    <shortLabel>myo5a-slc17a9-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-6931631" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21250-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1434728</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1434735">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6931634" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1434729</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1434736">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-6931633" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1434730</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>proximity</shortLabel>
                        <fullName>proximity</fullName>
                        <alias typeAc="MI:1041" type="synonym">close-contact colocalization</alias>
                        <alias typeAc="MI:1041" type="synonym">neighbourhood interaction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:2364" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-26564119" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">6b</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
