#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H633 uniprotkb:P78345 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366493|uniprotkb:Q53F71|uniprotkb:Q8NHS8|uniprotkb:B3KPY0|uniprotkb:D3DRT8|ensembl:ENSP00000367439|ensembl:ENSP00000367444|ensembl:ENSP00000367445|ensembl:ENSP00000478982 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:rpp38_human(display_long)|uniprotkb:RPP38(gene name)|psi-mi:RPP38(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_001091059.1|refseq:NP_006405.2|refseq:NP_892117.1|refseq:NP_001252530.1|refseq:XP_011517595.1|ensembl:ENSG00000152464(gene)|ensembl:ENST00000378197(transcript)|ensembl:ENST00000378202(transcript)|ensembl:ENST00000378203(transcript)|ensembl:ENST00000616640(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|interpro:IPR042848|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_006717426.1|refseq:XP_006717427.1|refseq:XP_016870968.1|refseq:XP_016870969.1|refseq:XP_016870970.1 - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:bXwC7yDxlK7pxJPKe79uhkVMBj09606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H633 uniprotkb:O75818 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366505|uniprotkb:Q8WVK8|uniprotkb:Q5VX97|ensembl:ENSP00000369391 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:rpp40_human(display_long)|uniprotkb:RPP40(gene name)|psi-mi:RPP40(display_short)|uniprotkb:RNASEP1(gene name synonym)|uniprotkb:RNase P subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_001273061.1|refseq:NP_001273062.1|refseq:NP_006629.2|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:1905267"(endonucleolytic cleavage involved in tRNA processing)|interpro:IPR013893(Ribonuclease P, Rpp40)|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6AHV|reactome:R-HSA-6784531|reactome:R-HSA-6791226|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000124787(gene)|ensembl:ENST00000380051(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001682"(tRNA 5'-leader removal) - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:osKnYk6H7n8lXec/a3T38grQsFE9606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H633 uniprotkb:Q99575 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H633 uniprotkb:P78346 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366553|uniprotkb:B2R799|uniprotkb:E9PB02|ensembl:ENSP00000360768 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:rpp30_human(display_long)|uniprotkb:RPP30(gene name)|psi-mi:RPP30(display_short)|uniprotkb:RNASEP2(gene name synonym)|uniprotkb:RNase P subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_001098016.1|refseq:NP_006404.1|refseq:XP_011537422.1|refseq:XP_011537423.1|ensembl:ENSG00000148688(gene)|ensembl:ENST00000371703(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P78346|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016870964.1|refseq:XP_016870966.1 - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:pRHvUnpzpNHGzYbS+kRiSa0m71E9606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H633 uniprotkb:O95707 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366477|uniprotkb:Q5XKL7|uniprotkb:Q9UQQ3|uniprotkb:Q6FHW9|ensembl:ENSP00000465213 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:rpp29_human(display_long)|uniprotkb:POP4(gene name)|psi-mi:POP4(display_short)|uniprotkb:RPP29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_006618.1|ensembl:ENSG00000105171(gene)|ensembl:ENST00000585603(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030677"(ribonuclease P complex)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002730(Ribonuclease P/MRP, p29 subunit, eukaryotic/archaeal)|interpro:IPR016848(Ribonuclease P/MRP, p29 subunit, eukaryotic)|interpro:IPR023534|interpro:IPR036980|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:4cCOti0t03LPAs0kk7VKGpniBOg9606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H633 uniprotkb:O75817 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366574|uniprotkb:Q9BV74|uniprotkb:A4D2E0|ensembl:ENSP00000304353 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:pop7_human(display_long)|uniprotkb:POP7(gene name)|psi-mi:POP7(display_short)|uniprotkb:RPP20(gene name synonym)|uniprotkb:Ribonucleases P/MRP protein subunit POP7 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_005828.2|ensembl:ENSG00000172336(gene)|ensembl:ENST00000303151(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR014612(RNase P/MRP, subunit p20)|interpro:IPR036882|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6CWX|rcsb pdb:6LT7|reactome:R-HSA-6784531 - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:4mEMPOJULq64MzFbKwpTygnJckY9606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H633 uniprotkb:Q9BUL9 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366570|uniprotkb:Q9NX88|uniprotkb:D3DW70|ensembl:ENSP00000317691 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:rpp25_human(display_long)|uniprotkb:RPP25(gene name)|psi-mi:RPP25(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_060263.2|ensembl:ENSG00000178718(gene)|ensembl:ENST00000322177(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0034451"(centriolar satellite)|interpro:IPR036882|interpro:IPR040207|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6CWX|rcsb pdb:6LT7|reactome:R-HSA-6784531|reactome:R-HSA-6791226|interpro:IPR002775(Alba, DNA/RNA-binding protein) - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:NznOkFRS7oRR0TM13Bo2UUd4sxw9606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H633 uniprotkb:Q969H6 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366525|uniprotkb:Q53FS5|uniprotkb:Q9Y2Q6|uniprotkb:A6NL80|ensembl:ENSP00000350098 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:pop5_human(display_long)|uniprotkb:POP5(gene name)|psi-mi:POP5(display_short)|uniprotkb:AD-008(orf name)|uniprotkb:HSPC004(orf name)|uniprotkb:x0003(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_057002.2|refseq:NP_937845.1|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR016819(Ribonuclease P/MRP protein, subunit Pop5)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|ensembl:ENSG00000167272(gene)|ensembl:ENST00000357500(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus) - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:WYNesu92ICtpEM2lwO63c6hjcMY9606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H633 uniprotkb:O95059 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 intact:EBI-366542|uniprotkb:Q53X97|ensembl:ENSP00000295959|ensembl:ENSP00000412894|ensembl:ENSP00000419909 psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:rpp14_human(display_long)|uniprotkb:RPP14(gene name)|psi-mi:RPP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957368|imex:IM-29403-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 refseq:NP_001092253.1|refseq:NP_008973.1|refseq:XP_011531615.1|ensembl:ENSG00000163684(gene)|ensembl:ENST00000295959(transcript)|ensembl:ENST00000445193(transcript)|ensembl:ENST00000466547(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016861130.1 - - - figure legend:Supp Fig 1A, 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 rogid:AkWjhZHJfUFybIAsMV1uGgXEKIs9606 rigid:VypQcPXU7irfGZN9Bj8oh9ubhZ0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-28957446 uniprotkb:Q99575 rnacentral:URS000013F331_9606 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:Q969H6 rnacentral:URS000013F331_9606 intact:EBI-366525|uniprotkb:Q53FS5|uniprotkb:Q9Y2Q6|uniprotkb:A6NL80|ensembl:ENSP00000350098 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:pop5_human(display_long)|uniprotkb:POP5(gene name)|psi-mi:POP5(display_short)|uniprotkb:AD-008(orf name)|uniprotkb:HSPC004(orf name)|uniprotkb:x0003(orf name) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_057002.2|refseq:NP_937845.1|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR016819(Ribonuclease P/MRP protein, subunit Pop5)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|ensembl:ENSG00000167272(gene)|ensembl:ENST00000357500(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:WYNesu92ICtpEM2lwO63c6hjcMY9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:O75817 rnacentral:URS000013F331_9606 intact:EBI-366574|uniprotkb:Q9BV74|uniprotkb:A4D2E0|ensembl:ENSP00000304353 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:pop7_human(display_long)|uniprotkb:POP7(gene name)|psi-mi:POP7(display_short)|uniprotkb:RPP20(gene name synonym)|uniprotkb:Ribonucleases P/MRP protein subunit POP7 homolog(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_005828.2|ensembl:ENSG00000172336(gene)|ensembl:ENST00000303151(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR014612(RNase P/MRP, subunit p20)|interpro:IPR036882|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6CWX|rcsb pdb:6LT7|reactome:R-HSA-6784531 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:4mEMPOJULq64MzFbKwpTygnJckY9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:O95059 rnacentral:URS000013F331_9606 intact:EBI-366542|uniprotkb:Q53X97|ensembl:ENSP00000295959|ensembl:ENSP00000412894|ensembl:ENSP00000419909 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp14_human(display_long)|uniprotkb:RPP14(gene name)|psi-mi:RPP14(display_short) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001092253.1|refseq:NP_008973.1|refseq:XP_011531615.1|ensembl:ENSG00000163684(gene)|ensembl:ENST00000295959(transcript)|ensembl:ENST00000445193(transcript)|ensembl:ENST00000466547(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016861130.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:AkWjhZHJfUFybIAsMV1uGgXEKIs9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:Q9H633 rnacentral:URS000013F331_9606 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 - false - strep tag:c-c 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:Q9BUL9 rnacentral:URS000013F331_9606 intact:EBI-366570|uniprotkb:Q9NX88|uniprotkb:D3DW70|ensembl:ENSP00000317691 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp25_human(display_long)|uniprotkb:RPP25(gene name)|psi-mi:RPP25(display_short) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_060263.2|ensembl:ENSG00000178718(gene)|ensembl:ENST00000322177(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0034451"(centriolar satellite)|interpro:IPR036882|interpro:IPR040207|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6CWX|rcsb pdb:6LT7|reactome:R-HSA-6784531|reactome:R-HSA-6791226|interpro:IPR002775(Alba, DNA/RNA-binding protein) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:NznOkFRS7oRR0TM13Bo2UUd4sxw9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:O95707 rnacentral:URS000013F331_9606 intact:EBI-366477|uniprotkb:Q5XKL7|uniprotkb:Q9UQQ3|uniprotkb:Q6FHW9|ensembl:ENSP00000465213 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp29_human(display_long)|uniprotkb:POP4(gene name)|psi-mi:POP4(display_short)|uniprotkb:RPP29(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_006618.1|ensembl:ENSG00000105171(gene)|ensembl:ENST00000585603(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030677"(ribonuclease P complex)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002730(Ribonuclease P/MRP, p29 subunit, eukaryotic/archaeal)|interpro:IPR016848(Ribonuclease P/MRP, p29 subunit, eukaryotic)|interpro:IPR023534|interpro:IPR036980|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:4cCOti0t03LPAs0kk7VKGpniBOg9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:P78346 rnacentral:URS000013F331_9606 intact:EBI-366553|uniprotkb:B2R799|uniprotkb:E9PB02|ensembl:ENSP00000360768 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp30_human(display_long)|uniprotkb:RPP30(gene name)|psi-mi:RPP30(display_short)|uniprotkb:RNASEP2(gene name synonym)|uniprotkb:RNase P subunit 2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001098016.1|refseq:NP_006404.1|refseq:XP_011537422.1|refseq:XP_011537423.1|ensembl:ENSG00000148688(gene)|ensembl:ENST00000371703(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P78346|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016870964.1|refseq:XP_016870966.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:pRHvUnpzpNHGzYbS+kRiSa0m71E9606 - false - - 1 2 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:P78345 rnacentral:URS000013F331_9606 intact:EBI-366493|uniprotkb:Q53F71|uniprotkb:Q8NHS8|uniprotkb:B3KPY0|uniprotkb:D3DRT8|ensembl:ENSP00000367439|ensembl:ENSP00000367444|ensembl:ENSP00000367445|ensembl:ENSP00000478982 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp38_human(display_long)|uniprotkb:RPP38(gene name)|psi-mi:RPP38(display_short) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001091059.1|refseq:NP_006405.2|refseq:NP_892117.1|refseq:NP_001252530.1|refseq:XP_011517595.1|ensembl:ENSG00000152464(gene)|ensembl:ENST00000378197(transcript)|ensembl:ENST00000378202(transcript)|ensembl:ENST00000378203(transcript)|ensembl:ENST00000616640(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|interpro:IPR042848|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_006717426.1|refseq:XP_006717427.1|refseq:XP_016870968.1|refseq:XP_016870969.1|refseq:XP_016870970.1 - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:bXwC7yDxlK7pxJPKe79uhkVMBj09606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:O75818 rnacentral:URS000013F331_9606 intact:EBI-366505|uniprotkb:Q8WVK8|uniprotkb:Q5VX97|ensembl:ENSP00000369391 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp40_human(display_long)|uniprotkb:RPP40(gene name)|psi-mi:RPP40(display_short)|uniprotkb:RNASEP1(gene name synonym)|uniprotkb:RNase P subunit 1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957387|emdb:EMD-9626|wwpdb:6ahr|imex:IM-29403-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001273061.1|refseq:NP_001273062.1|refseq:NP_006629.2|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:1905267"(endonucleolytic cleavage involved in tRNA processing)|interpro:IPR013893(Ribonuclease P, Rpp40)|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6AHV|reactome:R-HSA-6784531|reactome:R-HSA-6791226|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000124787(gene)|ensembl:ENST00000380051(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001682"(tRNA 5'-leader removal) - - - figure legend:Supp Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:osKnYk6H7n8lXec/a3T38grQsFE9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:Q99575 rnacentral:URS000013F331_9606 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:Q969H6 rnacentral:URS000013F331_9606 intact:EBI-366525|uniprotkb:Q53FS5|uniprotkb:Q9Y2Q6|uniprotkb:A6NL80|ensembl:ENSP00000350098 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:pop5_human(display_long)|uniprotkb:POP5(gene name)|psi-mi:POP5(display_short)|uniprotkb:AD-008(orf name)|uniprotkb:HSPC004(orf name)|uniprotkb:x0003(orf name) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_057002.2|refseq:NP_937845.1|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR016819(Ribonuclease P/MRP protein, subunit Pop5)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|ensembl:ENSG00000167272(gene)|ensembl:ENST00000357500(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:WYNesu92ICtpEM2lwO63c6hjcMY9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:O75817 rnacentral:URS000013F331_9606 intact:EBI-366574|uniprotkb:Q9BV74|uniprotkb:A4D2E0|ensembl:ENSP00000304353 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:pop7_human(display_long)|uniprotkb:POP7(gene name)|psi-mi:POP7(display_short)|uniprotkb:RPP20(gene name synonym)|uniprotkb:Ribonucleases P/MRP protein subunit POP7 homolog(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_005828.2|ensembl:ENSG00000172336(gene)|ensembl:ENST00000303151(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR014612(RNase P/MRP, subunit p20)|interpro:IPR036882|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6CWX|rcsb pdb:6LT7|reactome:R-HSA-6784531 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:4mEMPOJULq64MzFbKwpTygnJckY9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:O95059 rnacentral:URS000013F331_9606 intact:EBI-366542|uniprotkb:Q53X97|ensembl:ENSP00000295959|ensembl:ENSP00000412894|ensembl:ENSP00000419909 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp14_human(display_long)|uniprotkb:RPP14(gene name)|psi-mi:RPP14(display_short) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001092253.1|refseq:NP_008973.1|refseq:XP_011531615.1|ensembl:ENSG00000163684(gene)|ensembl:ENST00000295959(transcript)|ensembl:ENST00000445193(transcript)|ensembl:ENST00000466547(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002759(Ribonuclease P-related)|interpro:IPR038085|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016861130.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:AkWjhZHJfUFybIAsMV1uGgXEKIs9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:Q9H633 rnacentral:URS000013F331_9606 intact:EBI-366586|uniprotkb:B0S835|uniprotkb:Q5JPL9|uniprotkb:Q5STF9|uniprotkb:Q5SU42|uniprotkb:Q86Y49|uniprotkb:Q86Y50|uniprotkb:Q86Y51|uniprotkb:Q96F16|uniprotkb:B0S834|uniprotkb:A2AAZ8|uniprotkb:Q5STF8|uniprotkb:Q5STG2|uniprotkb:Q5JPM1|uniprotkb:Q5SU41|ensembl:ENSP00000365829|ensembl:ENSP00000398396|ensembl:ENSP00000399295|ensembl:ENSP00000403833|ensembl:ENSP00000404312|ensembl:ENSP00000414284 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp21_human(display_long)|uniprotkb:RPP21(gene name)|psi-mi:RPP21(display_short)|uniprotkb:C6orf135(gene name synonym)|uniprotkb:CAT60(gene name synonym)|uniprotkb:Ribonucleoprotein V(gene name synonym)|uniprotkb:Ribonuclease P/MRP 21 kDa subunit(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001186049.1|refseq:NP_001186050.1|refseq:NP_079115.1|ensembl:ENSG00000239927(gene)|ensembl:ENSG00000241370(gene)|ensembl:ENSG00000241779(gene)|ensembl:ENSG00000241863(gene)|ensembl:ENSG00000242726(gene)|ensembl:ENSG00000243009(gene)|ensembl:ENST00000376642(transcript)|ensembl:ENST00000414187(transcript)|ensembl:ENST00000416977(transcript)|ensembl:ENST00000424616(transcript)|ensembl:ENST00000434282(transcript)|ensembl:ENST00000442966(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|interpro:IPR007175(RNAse P, Rpr2/Rpp21 subunit)|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:h8+4VA4gmUqecxZN1ABi09J6Vww9606 - false - strep tag:c-c 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:Q9BUL9 rnacentral:URS000013F331_9606 intact:EBI-366570|uniprotkb:Q9NX88|uniprotkb:D3DW70|ensembl:ENSP00000317691 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp25_human(display_long)|uniprotkb:RPP25(gene name)|psi-mi:RPP25(display_short) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_060263.2|ensembl:ENSG00000178718(gene)|ensembl:ENST00000322177(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0034451"(centriolar satellite)|interpro:IPR036882|interpro:IPR040207|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6CWX|rcsb pdb:6LT7|reactome:R-HSA-6784531|reactome:R-HSA-6791226|interpro:IPR002775(Alba, DNA/RNA-binding protein) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:NznOkFRS7oRR0TM13Bo2UUd4sxw9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:O95707 rnacentral:URS000013F331_9606 intact:EBI-366477|uniprotkb:Q5XKL7|uniprotkb:Q9UQQ3|uniprotkb:Q6FHW9|ensembl:ENSP00000465213 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp29_human(display_long)|uniprotkb:POP4(gene name)|psi-mi:POP4(display_short)|uniprotkb:RPP29(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_006618.1|ensembl:ENSG00000105171(gene)|ensembl:ENST00000585603(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030677"(ribonuclease P complex)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002730(Ribonuclease P/MRP, p29 subunit, eukaryotic/archaeal)|interpro:IPR016848(Ribonuclease P/MRP, p29 subunit, eukaryotic)|interpro:IPR023534|interpro:IPR036980|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:4cCOti0t03LPAs0kk7VKGpniBOg9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:P78346 rnacentral:URS000013F331_9606 intact:EBI-366553|uniprotkb:B2R799|uniprotkb:E9PB02|ensembl:ENSP00000360768 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp30_human(display_long)|uniprotkb:RPP30(gene name)|psi-mi:RPP30(display_short)|uniprotkb:RNASEP2(gene name synonym)|uniprotkb:RNase P subunit 2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001098016.1|refseq:NP_006404.1|refseq:XP_011537422.1|refseq:XP_011537423.1|ensembl:ENSG00000148688(gene)|ensembl:ENST00000371703(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P78346|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016870964.1|refseq:XP_016870966.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:pRHvUnpzpNHGzYbS+kRiSa0m71E9606 - false - - 1 2 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:P78345 rnacentral:URS000013F331_9606 intact:EBI-366493|uniprotkb:Q53F71|uniprotkb:Q8NHS8|uniprotkb:B3KPY0|uniprotkb:D3DRT8|ensembl:ENSP00000367439|ensembl:ENSP00000367444|ensembl:ENSP00000367445|ensembl:ENSP00000478982 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp38_human(display_long)|uniprotkb:RPP38(gene name)|psi-mi:RPP38(display_short) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001091059.1|refseq:NP_006405.2|refseq:NP_892117.1|refseq:NP_001252530.1|refseq:XP_011517595.1|ensembl:ENSG00000152464(gene)|ensembl:ENST00000378197(transcript)|ensembl:ENST00000378202(transcript)|ensembl:ENST00000378203(transcript)|ensembl:ENST00000616640(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|interpro:IPR042848|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_006717426.1|refseq:XP_006717427.1|refseq:XP_016870968.1|refseq:XP_016870969.1|refseq:XP_016870970.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:bXwC7yDxlK7pxJPKe79uhkVMBj09606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 uniprotkb:O75818 rnacentral:URS000013F331_9606 intact:EBI-366505|uniprotkb:Q8WVK8|uniprotkb:Q5VX97|ensembl:ENSP00000369391 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:rpp40_human(display_long)|uniprotkb:RPP40(gene name)|psi-mi:RPP40(display_short)|uniprotkb:RNASEP1(gene name synonym)|uniprotkb:RNase P subunit 1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001273061.1|refseq:NP_001273062.1|refseq:NP_006629.2|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:1905267"(endonucleolytic cleavage involved in tRNA processing)|interpro:IPR013893(Ribonuclease P, Rpp40)|rcsb pdb:6AHR|rcsb pdb:6AHU|rcsb pdb:6AHV|reactome:R-HSA-6784531|reactome:R-HSA-6791226|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000124787(gene)|ensembl:ENST00000380051(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001682"(tRNA 5'-leader removal) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - rogid:osKnYk6H7n8lXec/a3T38grQsFE9606 - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) intact:EBI-28957446 intact:EBI-28957466 rnacentral:URS000013F331_9606 rnacentral:URS0000E60B72_9606 psi-mi:h1_human_rna(display_short)|psi-mi:EBI-28957446(display_long) psi-mi:trnaval_human_trna(display_short)|psi-mi:EBI-28957466(display_long) psi-mi:"MI:0410"(3D electron microscopy) Wu et al. (2018) pubmed:30454648|imex:IM-29403 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-28957452|emdb:EMD-9627|wwpdb:6AHU|imex:IM-29403-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0318"(nucleic acid) psi-mi:"MI:0325"(transfer rna) - - - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2022/01/04 2022/01/04 - - - false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)