#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0A812	uniprotkb:P0A809	intact:EBI-557878|uniprotkb:P08577|ensemblbacteria:AAC74930|ensemblbacteria:BAA15671	intact:EBI-555119|uniprotkb:P08576|ensemblbacteria:AAC74931|ensemblbacteria:BAA15672	psi-mi:ruvb_ecoli(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:b1860(locus name)|uniprotkb:JW1849(locus name)	psi-mi:ruva_ecoli(display_long)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short)|uniprotkb:b1861(locus name)|uniprotkb:JW1850(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299177|imex:IM-27919-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416374.1|refseq:WP_000568519.1|dip:DIP-47870N|ensemblbacteria:AAC74930(transcript)|ensemblbacteria:b1860(gene)|ensemblbacteria:BAA15671(gene)|ensemblbacteria:BAA15671(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009411"(response to UV)|go:"GO:0009432"(SOS response)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445	refseq:NP_416375.1|refseq:WP_000580323.1|dip:DIP-48064N|ensemblbacteria:AAC74931(transcript)|ensemblbacteria:b1861(gene)|ensemblbacteria:BAA15672(gene)|ensemblbacteria:BAA15672(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009314"(response to radiation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009379"(Holliday junction helicase complex)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011114(DNA helicase, Holliday junction RuvA type, C-terminal domain III)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR036267|rcsb pdb:1BDX|rcsb pdb:1C7Y|rcsb pdb:1CUK|rcsb pdb:1D8L|rcsb pdb:1HJP	-	-	-	figure legend:Fig 1A|comment:Interaction observed in the presence and absence of duplex DNA or Holliday junction DNA|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:Is8hGLVpuoDAHX8nKzAhBxBJL6w83333	rogid:HKLZjer/zJ8LRziQO5C7ISpkr7883333	rigid:ldWeSGGHpzjze+SpQU1E4rM04ZU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A812	uniprotkb:P0A809	intact:EBI-557878|uniprotkb:P08577|ensemblbacteria:AAC74930|ensemblbacteria:BAA15671	intact:EBI-555119|uniprotkb:P08576|ensemblbacteria:AAC74931|ensemblbacteria:BAA15672	psi-mi:ruvb_ecoli(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:b1860(locus name)|uniprotkb:JW1849(locus name)	psi-mi:ruva_ecoli(display_long)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short)|uniprotkb:b1861(locus name)|uniprotkb:JW1850(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299186|imex:IM-27919-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416374.1|refseq:WP_000568519.1|dip:DIP-47870N|ensemblbacteria:AAC74930(transcript)|ensemblbacteria:b1860(gene)|ensemblbacteria:BAA15671(gene)|ensemblbacteria:BAA15671(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009411"(response to UV)|go:"GO:0009432"(SOS response)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445	refseq:NP_416375.1|refseq:WP_000580323.1|dip:DIP-48064N|ensemblbacteria:AAC74931(transcript)|ensemblbacteria:b1861(gene)|ensemblbacteria:BAA15672(gene)|ensemblbacteria:BAA15672(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009314"(response to radiation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009379"(Holliday junction helicase complex)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011114(DNA helicase, Holliday junction RuvA type, C-terminal domain III)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR036267|rcsb pdb:1BDX|rcsb pdb:1C7Y|rcsb pdb:1CUK|rcsb pdb:1D8L|rcsb pdb:1HJP	-	-	-	figure legend:Fig 1B|comment:Interaction observed in the presence and absence of duplex DNA or Holliday junction DNA|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:Is8hGLVpuoDAHX8nKzAhBxBJL6w83333	rogid:HKLZjer/zJ8LRziQO5C7ISpkr7883333	rigid:ldWeSGGHpzjze+SpQU1E4rM04ZU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A814	uniprotkb:P0A809	intact:EBI-1123014|uniprotkb:P24239|ensemblbacteria:AAC74933|ensemblbacteria:BAA15674	intact:EBI-555119|uniprotkb:P08576|ensemblbacteria:AAC74931|ensemblbacteria:BAA15672	psi-mi:ruvc_ecoli(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:b1863(locus name)|uniprotkb:JW1852(locus name)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)	psi-mi:ruva_ecoli(display_long)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short)|uniprotkb:b1861(locus name)|uniprotkb:JW1850(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299220|imex:IM-27919-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295503.1|ensemblbacteria:AAC74933(transcript)|ensemblbacteria:b1863(gene)|ensemblbacteria:BAA15674(gene)|ensemblbacteria:BAA15674(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0009314"(response to radiation)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR020563|interpro:IPR036397|rcsb pdb:1HJR|refseq:NP_416377.1|dip:DIP-35952N	refseq:NP_416375.1|refseq:WP_000580323.1|dip:DIP-48064N|ensemblbacteria:AAC74931(transcript)|ensemblbacteria:b1861(gene)|ensemblbacteria:BAA15672(gene)|ensemblbacteria:BAA15672(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009314"(response to radiation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009379"(Holliday junction helicase complex)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011114(DNA helicase, Holliday junction RuvA type, C-terminal domain III)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR036267|rcsb pdb:1BDX|rcsb pdb:1C7Y|rcsb pdb:1CUK|rcsb pdb:1D8L|rcsb pdb:1HJP	-	-	-	figure legend:Fig 1A|comment:In the presence of Holliday junction DNA, RuvA formed a complex with RuvC that was immunoprecipitated with the anti-RuvA  or the anti-RuvC.  Interaction only observed in the presence of Holliday junction DNA, but not duplex DNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:qot36+1fBwETwWSE//kqV3fjCMI83333	rogid:HKLZjer/zJ8LRziQO5C7ISpkr7883333	rigid:BWuQm9YmyIeoZqfyDA5LbH0Gwcc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A814	uniprotkb:P0A809	intact:EBI-1123014|uniprotkb:P24239|ensemblbacteria:AAC74933|ensemblbacteria:BAA15674	intact:EBI-555119|uniprotkb:P08576|ensemblbacteria:AAC74931|ensemblbacteria:BAA15672	psi-mi:ruvc_ecoli(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:b1863(locus name)|uniprotkb:JW1852(locus name)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)	psi-mi:ruva_ecoli(display_long)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short)|uniprotkb:b1861(locus name)|uniprotkb:JW1850(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299225|imex:IM-27919-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295503.1|ensemblbacteria:AAC74933(transcript)|ensemblbacteria:b1863(gene)|ensemblbacteria:BAA15674(gene)|ensemblbacteria:BAA15674(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0009314"(response to radiation)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR020563|interpro:IPR036397|rcsb pdb:1HJR|refseq:NP_416377.1|dip:DIP-35952N	refseq:NP_416375.1|refseq:WP_000580323.1|dip:DIP-48064N|ensemblbacteria:AAC74931(transcript)|ensemblbacteria:b1861(gene)|ensemblbacteria:BAA15672(gene)|ensemblbacteria:BAA15672(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009314"(response to radiation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009379"(Holliday junction helicase complex)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011114(DNA helicase, Holliday junction RuvA type, C-terminal domain III)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR036267|rcsb pdb:1BDX|rcsb pdb:1C7Y|rcsb pdb:1CUK|rcsb pdb:1D8L|rcsb pdb:1HJP	-	-	-	figure legend:Fig 1C|comment:In the presence of Holliday junction DNA, RuvA formed a complex with RuvC that was immunoprecipitated with the anti-RuvA  or the anti-RuvC.  Interaction only observed in the presence of Holliday junction DNA but not duplex DNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:qot36+1fBwETwWSE//kqV3fjCMI83333	rogid:HKLZjer/zJ8LRziQO5C7ISpkr7883333	rigid:BWuQm9YmyIeoZqfyDA5LbH0Gwcc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A809	uniprotkb:P0A812	intact:EBI-555119|uniprotkb:P08576|ensemblbacteria:AAC74931|ensemblbacteria:BAA15672	intact:EBI-557878|uniprotkb:P08577|ensemblbacteria:AAC74930|ensemblbacteria:BAA15671	psi-mi:ruva_ecoli(display_long)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short)|uniprotkb:b1861(locus name)|uniprotkb:JW1850(locus name)	psi-mi:ruvb_ecoli(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:b1860(locus name)|uniprotkb:JW1849(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299230|imex:IM-27919-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416375.1|refseq:WP_000580323.1|dip:DIP-48064N|ensemblbacteria:AAC74931(transcript)|ensemblbacteria:b1861(gene)|ensemblbacteria:BAA15672(gene)|ensemblbacteria:BAA15672(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009314"(response to radiation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009379"(Holliday junction helicase complex)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011114(DNA helicase, Holliday junction RuvA type, C-terminal domain III)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR036267|rcsb pdb:1BDX|rcsb pdb:1C7Y|rcsb pdb:1CUK|rcsb pdb:1D8L|rcsb pdb:1HJP	refseq:NP_416374.1|refseq:WP_000568519.1|dip:DIP-47870N|ensemblbacteria:AAC74930(transcript)|ensemblbacteria:b1860(gene)|ensemblbacteria:BAA15671(gene)|ensemblbacteria:BAA15671(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009411"(response to UV)|go:"GO:0009432"(SOS response)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445	-	-	-	figure legend:Fig 1A|comment:In the presence of Holliday junction DNA, RuvA formed a complex with RuvC that was immunoprecipitated with the anti-RuvA  or the anti-RuvC.  Interaction only observed in the presence of Holliday junction DNA but not duplex DNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:HKLZjer/zJ8LRziQO5C7ISpkr7883333	rogid:Is8hGLVpuoDAHX8nKzAhBxBJL6w83333	rigid:baThmZjsOY78Os//2DdqoSwH11s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A809	uniprotkb:P0A814	intact:EBI-555119|uniprotkb:P08576|ensemblbacteria:AAC74931|ensemblbacteria:BAA15672	intact:EBI-1123014|uniprotkb:P24239|ensemblbacteria:AAC74933|ensemblbacteria:BAA15674	psi-mi:ruva_ecoli(display_long)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short)|uniprotkb:b1861(locus name)|uniprotkb:JW1850(locus name)	psi-mi:ruvc_ecoli(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:b1863(locus name)|uniprotkb:JW1852(locus name)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299230|imex:IM-27919-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416375.1|refseq:WP_000580323.1|dip:DIP-48064N|ensemblbacteria:AAC74931(transcript)|ensemblbacteria:b1861(gene)|ensemblbacteria:BAA15672(gene)|ensemblbacteria:BAA15672(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009314"(response to radiation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009379"(Holliday junction helicase complex)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011114(DNA helicase, Holliday junction RuvA type, C-terminal domain III)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR036267|rcsb pdb:1BDX|rcsb pdb:1C7Y|rcsb pdb:1CUK|rcsb pdb:1D8L|rcsb pdb:1HJP	refseq:WP_001295503.1|ensemblbacteria:AAC74933(transcript)|ensemblbacteria:b1863(gene)|ensemblbacteria:BAA15674(gene)|ensemblbacteria:BAA15674(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0009314"(response to radiation)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR020563|interpro:IPR036397|rcsb pdb:1HJR|refseq:NP_416377.1|dip:DIP-35952N	-	-	-	figure legend:Fig 1A|comment:In the presence of Holliday junction DNA, RuvA formed a complex with RuvC that was immunoprecipitated with the anti-RuvA  or the anti-RuvC.  Interaction only observed in the presence of Holliday junction DNA but not duplex DNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:HKLZjer/zJ8LRziQO5C7ISpkr7883333	rogid:qot36+1fBwETwWSE//kqV3fjCMI83333	rigid:baThmZjsOY78Os//2DdqoSwH11s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A812	uniprotkb:P0A814	intact:EBI-557878|uniprotkb:P08577|ensemblbacteria:AAC74930|ensemblbacteria:BAA15671	intact:EBI-1123014|uniprotkb:P24239|ensemblbacteria:AAC74933|ensemblbacteria:BAA15674	psi-mi:ruvb_ecoli(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:b1860(locus name)|uniprotkb:JW1849(locus name)	psi-mi:ruvc_ecoli(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:b1863(locus name)|uniprotkb:JW1852(locus name)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299238|imex:IM-27919-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416374.1|refseq:WP_000568519.1|dip:DIP-47870N|ensemblbacteria:AAC74930(transcript)|ensemblbacteria:b1860(gene)|ensemblbacteria:BAA15671(gene)|ensemblbacteria:BAA15671(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009411"(response to UV)|go:"GO:0009432"(SOS response)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445	refseq:WP_001295503.1|ensemblbacteria:AAC74933(transcript)|ensemblbacteria:b1863(gene)|ensemblbacteria:BAA15674(gene)|ensemblbacteria:BAA15674(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0009314"(response to radiation)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR020563|interpro:IPR036397|rcsb pdb:1HJR|refseq:NP_416377.1|dip:DIP-35952N	-	-	-	figure legend:Fig 1B|comment:Interaction only observed in the presence of Holliday junction DNA but not duplex DNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:Is8hGLVpuoDAHX8nKzAhBxBJL6w83333	rogid:qot36+1fBwETwWSE//kqV3fjCMI83333	rigid:baThmZjsOY78Os//2DdqoSwH11s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A812	uniprotkb:P0A809	intact:EBI-557878|uniprotkb:P08577|ensemblbacteria:AAC74930|ensemblbacteria:BAA15671	intact:EBI-555119|uniprotkb:P08576|ensemblbacteria:AAC74931|ensemblbacteria:BAA15672	psi-mi:ruvb_ecoli(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:b1860(locus name)|uniprotkb:JW1849(locus name)	psi-mi:ruva_ecoli(display_long)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short)|uniprotkb:b1861(locus name)|uniprotkb:JW1850(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299238|imex:IM-27919-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416374.1|refseq:WP_000568519.1|dip:DIP-47870N|ensemblbacteria:AAC74930(transcript)|ensemblbacteria:b1860(gene)|ensemblbacteria:BAA15671(gene)|ensemblbacteria:BAA15671(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009411"(response to UV)|go:"GO:0009432"(SOS response)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445	refseq:NP_416375.1|refseq:WP_000580323.1|dip:DIP-48064N|ensemblbacteria:AAC74931(transcript)|ensemblbacteria:b1861(gene)|ensemblbacteria:BAA15672(gene)|ensemblbacteria:BAA15672(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009314"(response to radiation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009379"(Holliday junction helicase complex)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011114(DNA helicase, Holliday junction RuvA type, C-terminal domain III)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR036267|rcsb pdb:1BDX|rcsb pdb:1C7Y|rcsb pdb:1CUK|rcsb pdb:1D8L|rcsb pdb:1HJP	-	-	-	figure legend:Fig 1B|comment:Interaction only observed in the presence of Holliday junction DNA but not duplex DNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:Is8hGLVpuoDAHX8nKzAhBxBJL6w83333	rogid:HKLZjer/zJ8LRziQO5C7ISpkr7883333	rigid:baThmZjsOY78Os//2DdqoSwH11s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A814	uniprotkb:P0A812	intact:EBI-1123014|uniprotkb:P24239|ensemblbacteria:AAC74933|ensemblbacteria:BAA15674	intact:EBI-557878|uniprotkb:P08577|ensemblbacteria:AAC74930|ensemblbacteria:BAA15671	psi-mi:ruvc_ecoli(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:b1863(locus name)|uniprotkb:JW1852(locus name)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)	psi-mi:ruvb_ecoli(display_long)|uniprotkb:ruvB(gene name)|psi-mi:ruvB(display_short)|uniprotkb:b1860(locus name)|uniprotkb:JW1849(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299244|imex:IM-27919-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295503.1|ensemblbacteria:AAC74933(transcript)|ensemblbacteria:b1863(gene)|ensemblbacteria:BAA15674(gene)|ensemblbacteria:BAA15674(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0009314"(response to radiation)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR020563|interpro:IPR036397|rcsb pdb:1HJR|refseq:NP_416377.1|dip:DIP-35952N	refseq:NP_416374.1|refseq:WP_000568519.1|dip:DIP-47870N|ensemblbacteria:AAC74930(transcript)|ensemblbacteria:b1860(gene)|ensemblbacteria:BAA15671(gene)|ensemblbacteria:BAA15671(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009411"(response to UV)|go:"GO:0009432"(SOS response)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004605(DNA helicase, Holliday junction RuvB type)|interpro:IPR008823(DNA helicase, Holliday junction RuvB type, C-terminal)|interpro:IPR008824(DNA helicase, Holliday junction RuvB type, N-terminal)|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041445	-	-	-	figure legend:Fig 1C|comment:Interaction only observed in the presence of Holliday junction DNA but not duplex DNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:qot36+1fBwETwWSE//kqV3fjCMI83333	rogid:Is8hGLVpuoDAHX8nKzAhBxBJL6w83333	rigid:baThmZjsOY78Os//2DdqoSwH11s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0A814	uniprotkb:P0A809	intact:EBI-1123014|uniprotkb:P24239|ensemblbacteria:AAC74933|ensemblbacteria:BAA15674	intact:EBI-555119|uniprotkb:P08576|ensemblbacteria:AAC74931|ensemblbacteria:BAA15672	psi-mi:ruvc_ecoli(display_long)|uniprotkb:ruvC(gene name)|psi-mi:ruvC(display_short)|uniprotkb:b1863(locus name)|uniprotkb:JW1852(locus name)|uniprotkb:Holliday junction nuclease RuvC(gene name synonym)|uniprotkb:Holliday junction resolvase RuvC(gene name synonym)	psi-mi:ruva_ecoli(display_long)|uniprotkb:ruvA(gene name)|psi-mi:ruvA(display_short)|uniprotkb:b1861(locus name)|uniprotkb:JW1850(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Davies et al. (1998)	imex:IM-27919|pubmed:9637927	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25299244|imex:IM-27919-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295503.1|ensemblbacteria:AAC74933(transcript)|ensemblbacteria:b1863(gene)|ensemblbacteria:BAA15674(gene)|ensemblbacteria:BAA15674(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008821"(crossover junction endodeoxyribonuclease activity)|go:"GO:0009314"(response to radiation)|go:"GO:0048476"(Holliday junction resolvase complex)|interpro:IPR002176(Crossover junction endodeoxyribonuclease RuvC)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR020563|interpro:IPR036397|rcsb pdb:1HJR|refseq:NP_416377.1|dip:DIP-35952N	refseq:NP_416375.1|refseq:WP_000580323.1|dip:DIP-48064N|ensemblbacteria:AAC74931(transcript)|ensemblbacteria:b1861(gene)|ensemblbacteria:BAA15672(gene)|ensemblbacteria:BAA15672(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000725"(recombinational repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0009314"(response to radiation)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0009379"(Holliday junction helicase complex)|go:"GO:0009432"(SOS response)|go:"GO:0042802"(identical protein binding)|go:"GO:0048476"(Holliday junction resolvase complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000085(Bacterial DNA recombination protein RuvA)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011114(DNA helicase, Holliday junction RuvA type, C-terminal domain III)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013849(DNA helicase, Holliday junction RuvA type, domain I, bacterial)|interpro:IPR036267|rcsb pdb:1BDX|rcsb pdb:1C7Y|rcsb pdb:1CUK|rcsb pdb:1D8L|rcsb pdb:1HJP	-	-	-	figure legend:Fig 1C|comment:Interaction only observed in the presence of Holliday junction DNA but not duplex DNA.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/03	2020/01/03	rogid:qot36+1fBwETwWSE//kqV3fjCMI83333	rogid:HKLZjer/zJ8LRziQO5C7ISpkr7883333	rigid:baThmZjsOY78Os//2DdqoSwH11s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)