#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06971	uniprotkb:P02929	intact:EBI-1116714|uniprotkb:P71280|uniprotkb:P75665|ensemblbacteria:AAC73261|ensemblbacteria:BAB96726	intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239	psi-mi:fhua_ecoli(display_long)|uniprotkb:JW0146(locus name)|uniprotkb:fhuA(gene name)|psi-mi:fhuA(display_short)|uniprotkb:tonA(gene name synonym)|uniprotkb:b0150(locus name)|uniprotkb:Ferric hydroxamate uptake(gene name synonym)|uniprotkb:Ferric hydroxamate receptor(gene name synonym)|uniprotkb:Ferrichrome-iron receptor(gene name synonym)	psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name)	psi-mi:"MI:0096"(pull down)	Moeck et al. (1997)	pubmed:9353297|imex:IM-28002	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608956|imex:IM-28002-5|dip:DIP-192945E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000124438.1|refseq:NP_414692.1|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039423|rcsb pdb:1BY3|rcsb pdb:1BY5|rcsb pdb:1FCP|rcsb pdb:1FI1|rcsb pdb:1QFF|rcsb pdb:1QFG|rcsb pdb:1QJQ|rcsb pdb:1QKC|rcsb pdb:2FCP|rcsb pdb:2GRX|rcsb pdb:4CU4|ensemblbacteria:AAC73261(transcript)|ensemblbacteria:b0150(gene)|ensemblbacteria:BAB96726(gene)|ensemblbacteria:BAB96726(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0046790"(virion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|dip:DIP-9602N	refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N	psi-mi:"MI:0465"(dip)	-	-	agonist:"Ferricrocin (CHEBI:64492)"|figure legend:Fig. 3|agonist:Colicin M|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/05/12	2020/05/14	rogid:YuhazS970KcEsyZqYsiK4AAwsqI83333	rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333	rigid:8NqHZK5tzwZypyXFKqatMTiRupo	false	his tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06971	uniprotkb:P02929	intact:EBI-1116714|uniprotkb:P71280|uniprotkb:P75665|ensemblbacteria:AAC73261|ensemblbacteria:BAB96726	intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239	psi-mi:fhua_ecoli(display_long)|uniprotkb:JW0146(locus name)|uniprotkb:fhuA(gene name)|psi-mi:fhuA(display_short)|uniprotkb:tonA(gene name synonym)|uniprotkb:b0150(locus name)|uniprotkb:Ferric hydroxamate uptake(gene name synonym)|uniprotkb:Ferric hydroxamate receptor(gene name synonym)|uniprotkb:Ferrichrome-iron receptor(gene name synonym)	psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name)	psi-mi:"MI:0096"(pull down)	Moeck et al. (1997)	pubmed:9353297|imex:IM-28002	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608942|imex:IM-28002-1|dip:DIP-192945E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000124438.1|refseq:NP_414692.1|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039423|rcsb pdb:1BY3|rcsb pdb:1BY5|rcsb pdb:1FCP|rcsb pdb:1FI1|rcsb pdb:1QFF|rcsb pdb:1QFG|rcsb pdb:1QJQ|rcsb pdb:1QKC|rcsb pdb:2FCP|rcsb pdb:2GRX|rcsb pdb:4CU4|ensemblbacteria:AAC73261(transcript)|ensemblbacteria:b0150(gene)|ensemblbacteria:BAB96726(gene)|ensemblbacteria:BAB96726(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0046790"(virion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|dip:DIP-9602N	refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N	psi-mi:"MI:0465"(dip)	-	-	agonist:"Ferricrocin (CHEBI:64492)"|figure legend:Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/05/12	2020/05/14	rogid:YuhazS970KcEsyZqYsiK4AAwsqI83333	rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333	rigid:8NqHZK5tzwZypyXFKqatMTiRupo	false	his tag:?-?	sufficient binding region:1-65,101-239	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06971	uniprotkb:P02929	intact:EBI-1116714|uniprotkb:P71280|uniprotkb:P75665|ensemblbacteria:AAC73261|ensemblbacteria:BAB96726	intact:EBI-6399993|ensemblbacteria:AAC74334|ensemblbacteria:BAA14784|uniprotkb:P76831|uniprotkb:P94719|uniprotkb:P94722|uniprotkb:P94726|uniprotkb:P94728|uniprotkb:P94732|uniprotkb:P94736|uniprotkb:P94739|uniprotkb:P97239	psi-mi:fhua_ecoli(display_long)|uniprotkb:JW0146(locus name)|uniprotkb:fhuA(gene name)|psi-mi:fhuA(display_short)|uniprotkb:tonA(gene name synonym)|uniprotkb:b0150(locus name)|uniprotkb:Ferric hydroxamate uptake(gene name synonym)|uniprotkb:Ferric hydroxamate receptor(gene name synonym)|uniprotkb:Ferrichrome-iron receptor(gene name synonym)	psi-mi:tonb_ecoli(display_long)|uniprotkb:tonB(gene name)|psi-mi:tonB(display_short)|uniprotkb:exbA(gene name synonym)|uniprotkb:JW5195(locus name)|uniprotkb:b1252(locus name)	psi-mi:"MI:0030"(cross-linking study)	Moeck et al. (1997)	pubmed:9353297|imex:IM-28002	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608949|imex:IM-28002-3|dip:DIP-192945E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000124438.1|refseq:NP_414692.1|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039423|rcsb pdb:1BY3|rcsb pdb:1BY5|rcsb pdb:1FCP|rcsb pdb:1FI1|rcsb pdb:1QFF|rcsb pdb:1QFG|rcsb pdb:1QJQ|rcsb pdb:1QKC|rcsb pdb:2FCP|rcsb pdb:2GRX|rcsb pdb:4CU4|ensemblbacteria:AAC73261(transcript)|ensemblbacteria:b0150(gene)|ensemblbacteria:BAB96726(gene)|ensemblbacteria:BAB96726(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0046790"(virion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010105(TonB-dependent siderophore receptor)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|dip:DIP-9602N	refseq:WP_001360141.1|ensemblbacteria:AAC74334(transcript)|ensemblbacteria:b1252(gene)|ensemblbacteria:BAA14784(gene)|ensemblbacteria:BAA14784(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015889"(cobalamin transport)|go:"GO:0015891"(siderophore transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0030313"(cell envelope)|go:"GO:0031992"(energy transducer activity)|go:"GO:0042914"(colicin transport)|go:"GO:0071575"(integral component of external side of plasma membrane)|go:"GO:0098002"(receptor-mediated bacteriophage irreversible attachment to host cell)|go:"GO:0098797"(plasma membrane protein complex)|interpro:IPR003538(Gram-negative bacterial tonB protein)|interpro:IPR006260(TonB, C-terminal)|interpro:IPR037682|rcsb pdb:1IHR|rcsb pdb:1QXX|rcsb pdb:1U07|rcsb pdb:1XX3|rcsb pdb:2GRX|rcsb pdb:2GSK|refseq:NP_415768.1|dip:DIP-48111N	psi-mi:"MI:0465"(dip)	-	-	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/05/12	2020/05/14	rogid:YuhazS970KcEsyZqYsiK4AAwsqI83333	rogid:ia5lbqqvP+O4DJyZcLSRdxZV/tE83333	rigid:8NqHZK5tzwZypyXFKqatMTiRupo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)