#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q04338	uniprotkb:P32319	intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C	intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C	psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name)	psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name)	psi-mi:"MI:0018"(two hybrid)	von et al. (1997)	pubmed:9199167|imex:IM-27998	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608824|dip:DIP-10519E|imex:IM-27998-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338	refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278	psi-mi:"MI:0465"(dip)	crc64:E55B4DA3B40FAD67	crc64:C778A0400612ECF4	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/05/12	2020/05/15	rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292	rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292	rigid:GcQR/bxbhcFHAtwTd5E16LEN0hM	false	-	sufficient binding region:1413-1579	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32319	uniprotkb:Q04338	intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C	intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C	psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name)	psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	von et al. (1997)	pubmed:9199167|imex:IM-27998	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608836|dip:DIP-2378E|imex:IM-27998-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278	refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338	psi-mi:"MI:0465"(dip)	crc64:C778A0400612ECF4	crc64:E55B4DA3B40FAD67	figure legend:Fig 9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/05/12	2020/05/15	rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292	rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292	rigid:GcQR/bxbhcFHAtwTd5E16LEN0hM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P32854	uniprotkb:Q04338	intact:EBI-13098|ensemblfungi:YOR036W|uniprotkb:D6W2A3	intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C	psi-mi:pep12_yeast(display_long)|uniprotkb:PEP12(gene name)|psi-mi:PEP12(display_short)|uniprotkb:Vacuolar protein sorting-associated protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 13(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 12(gene name synonym)|uniprotkb:VPS6(gene name synonym)|uniprotkb:VPT13(gene name synonym)|uniprotkb:OR26.29(orf name)|uniprotkb:YOR036W(locus name)	psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name)	psi-mi:"MI:0096"(pull down)	von et al. (1997)	pubmed:9199167|imex:IM-27998	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608853|dip:DIP-2378E|imex:IM-27998-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOR036W(gene)|ensemblfungi:YOR036W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031201"(SNARE complex)|refseq:NP_014679.1|sgd:S000005562|mint:P32854|dip:DIP-2021N|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0048278"(vesicle docking)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-SCE-204005	refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338	psi-mi:"MI:0465"(dip)	crc64:D9F5711339DA1CDA	crc64:E55B4DA3B40FAD67	figure legend:Fig. 9B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/05/12	2020/05/15	rogid:RAEwrvQSX1rO6JTK4hInPnMkYKU559292	rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292	rigid:mLL2AlOFTKJLA/vat2aR/BLgYhM	false	glutathione s tranferase tag:n-n	his tag:n-n|sufficient binding region:1-194	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q01590	uniprotkb:Q04338	intact:EBI-16930|uniprotkb:D6VY28|ensemblfungi:YLR026C	intact:EBI-20519|uniprotkb:D6W022|ensemblfungi:YMR197C	psi-mi:sed5_yeast(display_long)|uniprotkb:SED5(gene name)|psi-mi:SED5(display_short)|uniprotkb:YLR026C(locus name)	psi-mi:vti1_yeast(display_long)|uniprotkb:VTI1(gene name)|psi-mi:VTI1(display_short)|uniprotkb:Qb-SNARE VTI1(gene name synonym)|uniprotkb:Vesicle transport v-SNARE protein VTI1(gene name synonym)|uniprotkb:VPS10-interacting protein 1(gene name synonym)|uniprotkb:YM9646.10C(orf name)|uniprotkb:YMR197C(locus name)	psi-mi:"MI:0096"(pull down)	von et al. (1997)	pubmed:9199167|imex:IM-27998	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-25608848|dip:DIP-10139E|imex:IM-27998-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013126.1|sgd:S000004016|ensemblfungi:YLR026C(gene)|ensemblfungi:YLR026C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0090083"(regulation of inclusion body assembly)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|rcsb pdb:1MQS|rcsb pdb:1PD0|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|reactome:R-SCE-204005|reactome:R-SCE-5694530|reactome:R-SCE-6807878|reactome:R-SCE-6811438|reactome:R-SCE-9609523|go:"GO:0031201"(SNARE complex)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|dip:DIP-2489N|mint:Q01590	refseq:NP_013924.1|sgd:S000004810|ensemblfungi:YMR197C(gene)|ensemblfungi:YMR197C_mRNA(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR007705(Vesicle transport v-SNARE)|interpro:IPR010989(t-SNARE)|interpro:IPR027027|interpro:IPR038407|rcsb pdb:3ONJ|rcsb pdb:3ONL|reactome:R-SCE-114608|reactome:R-SCE-6811440|dip:DIP-2145N|mint:Q04338	psi-mi:"MI:0465"(dip)	crc64:B3192B57269A0B83	crc64:E55B4DA3B40FAD67	figure legend:Fig. 9B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/05/12	2020/05/15	rogid:c+W+86qfjxcvWWJ9nMScyH5TjNA559292	rogid:G9j1gwSOXdJehkaciku6eKCvmXw559292	rigid:yCXpKVoEqtLxRWSQ00a1xRGDaqA	false	glutathione s tranferase tag:n-n	sufficient binding region:1-194|his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)