#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13219 uniprotkb:P13727 intact:EBI-1221991|uniprotkb:Q08371|uniprotkb:Q68G52|uniprotkb:Q9UDK7|uniprotkb:B1AMF9|ensembl:ENSP00000330658 intact:EBI-716689|uniprotkb:P81448|uniprotkb:Q14227|uniprotkb:Q6ICT2|uniprotkb:A6XMW0|uniprotkb:B2R5I1|ensembl:ENSP00000312134|ensembl:ENSP00000433016 psi-mi:papp1_human(display_long)|uniprotkb:PAPPA(gene name)|psi-mi:PAPPA(display_short)|uniprotkb:Pregnancy-associated plasma protein A(gene name synonym)|uniprotkb:Insulin-like growth factor-dependent IGF-binding protein 4 protease(gene name synonym) psi-mi:prg2_human(display_long)|uniprotkb:Proteoglycan 2(gene name synonym)|uniprotkb:PRG2(gene name)|psi-mi:PRG2(display_short)|uniprotkb:MBP(gene name synonym) psi-mi:"MI:0091"(chromatography technology) Oxvig et al. (1993) imex:IM-27990|pubmed:7685339 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25612691|imex:IM-27990-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002572.2|ensembl:ENSG00000182752(gene)|ensembl:ENST00000328252(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007565"(female pregnancy)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032354"(response to follicle-stimulating hormone)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0051384"(response to glucocorticoid)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR000800(Notch region)|interpro:IPR006558(LamG-like jellyroll fold)|interpro:IPR008754(Peptidase M43B, pregnancy-associated plasma-A)|interpro:IPR011936(Myxococcus cysteine-rich repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024079|interpro:IPR030433|interpro:IPR035976|interpro:IPR043543|reactome:R-HSA-381426 refseq:NP_001230174.1|refseq:NP_002719.3|refseq:NP_001289855.1|refseq:NP_001289856.1|go:"GO:0042742"(defense response to bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001304(C-type lectin)|interpro:IPR002352(Eosinophil major basic protein)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033816|rcsb pdb:1H8U|rcsb pdb:2BRS|rcsb pdb:4QXX|reactome:R-HSA-6798695|ensembl:ENSG00000186652(gene)|ensembl:ENST00000311862(transcript)|ensembl:ENST00000525955(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0008201"(heparin binding)|go:"GO:0030021"(extracellular matrix structural constituent conferring compression resistance)|go:"GO:0030133"(transport vesicle)|go:"GO:0030246"(carbohydrate binding) - - - figure legend:Fig 1-2, Tables 1-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-serum)|taxid:9606(Homo sapiens) - 2020/05/18 2020/06/12 rogid:N9by5mwLLG+HMB9KCZhmOP4tW5g9606 rogid:QlmkRH3H1EqzmXCOJvljPKWDncU9606 rigid:yF009Z+qaqylLHXBlFzQVKuI0YY false - - - - psi-mi:"MI:0082"(peptide massfingerprinting)|psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0082"(peptide massfingerprinting)|psi-mi:"MI:0039"(edman degradation)