#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09528 uniprotkb:P09528 intact:EBI-308950|uniprotkb:Q3UI44|ensembl:ENSMUSP00000025563|ensembl:ENSMUSP00000158539 intact:EBI-308950|uniprotkb:Q3UI44|ensembl:ENSMUSP00000025563|ensembl:ENSMUSP00000158539 psi-mi:frih_mouse(display_long)|uniprotkb:Fth1(gene name)|psi-mi:Fth1(display_short)|uniprotkb:Fth(gene name synonym) psi-mi:frih_mouse(display_long)|uniprotkb:Fth1(gene name)|psi-mi:Fth1(display_short)|uniprotkb:Fth(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Nakane et al. (2020) imex:IM-28884|pubmed:33087931 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-26495055|imex:IM-28884-1|wwpdb:7A4M|emdb:EMD-11638 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034369.1|ensembl:ENSMUSG00000024661(gene)|ensembl:ENSMUST00000025563(transcript)|ensembl:ENSMUST00000235196(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|mint:P09528|rcsb pdb:3WNW|go:"GO:0008285"(negative regulation of cell population proliferation)|rcsb pdb:5OBA|go:"GO:0044754"(autolysosome)|rcsb pdb:5OBB|go:"GO:0048147"(negative regulation of fibroblast proliferation)|rcsb pdb:6S61|rcsb pdb:6SHT|rcsb pdb:6V21|rcsb pdb:7A4M|rcsb pdb:7KOD|go:"GO:0071682"(endocytic vesicle lumen)|reactome:R-MMU-432722|reactome:R-MMU-6798695|reactome:R-MMU-917937|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site) refseq:NP_034369.1|ensembl:ENSMUSG00000024661(gene)|ensembl:ENSMUST00000025563(transcript)|ensembl:ENSMUST00000235196(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|mint:P09528|rcsb pdb:3WNW|go:"GO:0008285"(negative regulation of cell population proliferation)|rcsb pdb:5OBA|go:"GO:0044754"(autolysosome)|rcsb pdb:5OBB|go:"GO:0048147"(negative regulation of fibroblast proliferation)|rcsb pdb:6S61|rcsb pdb:6SHT|rcsb pdb:6V21|rcsb pdb:7A4M|rcsb pdb:7KOD|go:"GO:0071682"(endocytic vesicle lumen)|reactome:R-MMU-432722|reactome:R-MMU-6798695|reactome:R-MMU-917937|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site) - - - figure legend:Fig 1, Extended Data Fig 1, Extended Data Table 1, 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2020/11/30 2021/03/23 rogid:dg7aqsV02liocLxEKKesIMGxyWs10090 rogid:dg7aqsV02liocLxEKKesIMGxyWs10090 rigid:3d1quWFrABHCD7LGG9QCIABKI4M false - - 24 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)