#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:K9N5R3 uniprotkb:Q6DD88 intact:EBI-26374535 intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3 - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:P01861 intact:EBI-26374535 intact:EBI-7211518|intact:MINT-1179376|ensembl:ENSP00000374985|ensembl:ENSP00000483393 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:ighg4_human(display_long)|uniprotkb:IGHG4(gene name)|psi-mi:IGHG4(display_short)|uniprotkb:Ig gamma-4 chain C region(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 ensembl:ENSG00000211892(gene)|ensembl:ENSG00000277016(gene)|ensembl:ENST00000390543(transcript)|ensembl:ENST00000618981(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|rcsb pdb:3EO1|rcsb pdb:4B53|rcsb pdb:4C54|rcsb pdb:4C55|rcsb pdb:4D2N|rcsb pdb:5LG1|rcsb pdb:5W5M|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1ADQ|rcsb pdb:1BBJ|rcsb pdb:2FL5|rcsb pdb:5W5N - - comment:mint figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:YKNlRgWce2cKmaOA18mMfLMWRSY9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:Q9Y5L0 intact:EBI-26374535 intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9 - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:Q9UBS3 intact:EBI-26374535 intact:EBI-713124|ensembl:ENSP00000249356 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:dnjb9_human(display_long)|uniprotkb:Microvascular endothelial differentiation gene 1 protein(gene name synonym)|uniprotkb:DNAJB9(gene name)|psi-mi:DNAJB9(display_short)|uniprotkb:MDG1(gene name synonym)|uniprotkb:UNQ743/PRO1471(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 ensembl:ENSG00000128590(gene)|ensembl:ENST00000249356(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CTR|reactome:R-HSA-381038|go:"GO:0051787"(misfolded protein binding)|refseq:NP_036460.1 - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:yP4vHOlqhtk5d0T2FCSfRkbRdrY9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:Q9NPI6 intact:EBI-26374535 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:Q9BTV4 intact:EBI-26374535 intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625) - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:Q8WY22 intact:EBI-26374535 intact:EBI-359348|uniprotkb:Q8WY23|ensembl:ENSP00000340761|ensembl:ENSP00000500359 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:bri3b_human(display_long)|uniprotkb:BRI3BP(gene name)|psi-mi:BRI3BP(display_short)|uniprotkb:KG19(gene name synonym)|uniprotkb:Cervical cancer 1 proto-oncogene-binding protein KG19(gene name synonym)|uniprotkb:HCCRBP-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 refseq:NP_542193.3|ensembl:ENSG00000184992(gene)|ensembl:ENST00000341446(transcript)|ensembl:ENST00000672415(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR033367 - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:O9epHcfM1m7xNvrm6ELo0fRRGV49606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:Q8WVM8 intact:EBI-26374535 intact:EBI-722569|uniprotkb:O60754|uniprotkb:O94990|uniprotkb:Q7Z529|uniprotkb:Q9BZI3|uniprotkb:Q9UNL3|uniprotkb:Q9Y6A8|uniprotkb:A8K2Z5|uniprotkb:B7Z4U7|uniprotkb:B7Z594|ensembl:ENSP00000390783 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:scfd1_human(display_long)|uniprotkb:Syntaxin-binding protein 1-like 2(gene name synonym)|uniprotkb:SLY1 homolog(gene name synonym)|uniprotkb:FKSG23(orf name)|uniprotkb:SCFD1(gene name)|psi-mi:SCFD1(display_short)|uniprotkb:KIAA0917(gene name synonym)|uniprotkb:STXBP1L2(gene name synonym)|uniprotkb:C14orf163(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 refseq:NP_001269961.1|refseq:NP_057190.2|refseq:NP_001244305.1|refseq:NP_878255.1|mint:Q8WVM8|reactome:R-HSA-204005|reactome:R-HSA-8980692|ensembl:ENSG00000092108(gene)|ensembl:ENST00000458591(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1901998"(toxin transport)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154 - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:7cD2Z6zhuKLCd3ERB+pVNRdVexY9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:Q8IZ52 intact:EBI-26374535 intact:EBI-372500|uniprotkb:Q6UXD6|uniprotkb:Q7L4G1|uniprotkb:Q9H0F8|uniprotkb:Q9H618|ensembl:ENSP00000243776|uniprotkb:B4DXU0 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:chss2_human(display_long)|uniprotkb:UNQ651/PRO1281(orf name)|uniprotkb:Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II(gene name synonym)|uniprotkb:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II(gene name synonym)|uniprotkb:Chondroitin glucuronyltransferase 2(gene name synonym)|uniprotkb:N-acetylgalactosaminyltransferase 2(gene name synonym)|uniprotkb:Chondroitin-polymerizing factor(gene name synonym)|uniprotkb:CHPF(gene name)|psi-mi:CHPF(display_short)|uniprotkb:CSS2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 refseq:NP_001182660.1|refseq:NP_078812.2|ensembl:ENSG00000123989(gene)|ensembl:ENST00000243776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047238"(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0050510"(N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|reactome:R-HSA-2022870|go:"GO:0016021"(integral component of membrane) - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:jfN5U87odagTLP2MJVqowoS6TBw9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:Q5T9L3 intact:EBI-26374535 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:O75787 intact:EBI-26374535 intact:EBI-2512037|ensembl:ENSP00000490083|uniprotkb:B7Z9I3|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal accessory protein 2"(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal-interacting protein 2"(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 ensembl:ENSG00000182220(gene)|ensembl:ENST00000636580(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0021626"(central nervous system maturation)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048069"(eye pigmentation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2 - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:O43505 intact:EBI-26374535 intact:EBI-6138697|uniprotkb:Q4TTN0|ensembl:ENSP00000309096 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:b4ga1_human(display_long)|uniprotkb:B4GAT1(gene name)|psi-mi:B4GAT1(display_short)|uniprotkb:B3GNT1(gene name synonym)|uniprotkb:B3GNT6(gene name synonym)|uniprotkb:I-beta-1,3-N-acetylglucosaminyltransferase(gene name synonym)|uniprotkb:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase(gene name synonym)|uniprotkb:Poly-N-acetyllactosamine extension enzyme(gene name synonym)|uniprotkb:"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 refseq:NP_006867.1|dip:DIP-48921N|ensembl:ENSG00000174684(gene)|ensembl:ENST00000311181(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008532"(N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0018146"(keratan sulfate biosynthetic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR043189|reactome:R-HSA-2022854|reactome:R-HSA-5083627|reactome:R-HSA-5173105 - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:385SVje+9APXIP/uy7JT3ybCqpA9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5R3 uniprotkb:O15270 intact:EBI-26374535 intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484 psi-mi:vemp_mers1(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374533|imex:IM-28441-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR043506|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR044379 refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661 - - - figure legend:Table S2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:faXUcv0htunomX+0C6MTJT2AJu41263720 rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606 rigid:i2lEkIsNZxNoXTEvaqL1BVo7K2M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9Y4R8 intact:EBI-25754632 intact:EBI-1043674|uniprotkb:O75168|uniprotkb:Q7LDV4|uniprotkb:Q9BR21|intact:EBI-725566|intact:EBI-1047721|ensembl:ENSP00000262319|uniprotkb:D3DU73 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:telo2_human(display_long)|uniprotkb:TELO2(gene name)|psi-mi:TELO2(display_short)|uniprotkb:KIAA0683(gene name synonym)|uniprotkb:Protein clk-2 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 ensembl:ENSG00000100726(gene)|ensembl:ENST00000262319(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070209"(ASTRA complex)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019337|interpro:IPR038528|mint:Q9Y4R8|rcsb pdb:4PSI|refseq:NP_057195.2|refseq:XP_016879403.1|dip:DIP-40568N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:AnKk5b5Bc/tzEEz+p68m5uQUZVY9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9UI26 intact:EBI-25754632 intact:EBI-748752|uniprotkb:B4DZ73|uniprotkb:Q8N5R2|uniprotkb:Q9NSJ6|uniprotkb:Q9NVB1|uniprotkb:A6NGJ5|uniprotkb:D3DW98|ensembl:ENSP00000316651 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ipo11_human(display_long)|uniprotkb:Ran-binding protein 11(gene name synonym)|uniprotkb:IPO11(gene name)|psi-mi:IPO11(display_short)|uniprotkb:RANBP11(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_001128251.1|refseq:NP_057422.3|ensembl:ENSG00000086200(gene)|ensembl:ENST00000325324(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UI26 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:OTTaVDNCpSJLcEJCkdb7f+DkADo9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9NX47 intact:EBI-25754632 intact:EBI-2341610|ensembl:ENSP00000351813 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9NVI1 intact:EBI-25754632 intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9H583 intact:EBI-25754632 intact:EBI-1048716|uniprotkb:Q5T3Q8|uniprotkb:Q6P197|uniprotkb:Q9NW23|ensembl:ENSP00000355541 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:heat1_human(display_long)|uniprotkb:Protein BAP28(gene name synonym)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)|uniprotkb:BAP28(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 10 homolog(gene name synonym)|uniprotkb:UTP10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_060542.4|ensembl:ENSG00000119285(gene)|ensembl:ENST00000366582(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022125|interpro:IPR040191|mint:Q9H583|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:0WoP84UUVfXWppmvCYa/n5GTzc89606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9H0V9 intact:EBI-25754632 intact:EBI-9091707|uniprotkb:Q53S67|uniprotkb:Q8NBQ6|uniprotkb:D3DXH6|uniprotkb:Q63HN6|uniprotkb:Q53GV3|uniprotkb:Q9BQ14|uniprotkb:B4DSH3|ensembl:ENSP00000264963 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:lma2l_human(display_long)|uniprotkb:Lectin mannose-binding 2-like(gene name synonym)|uniprotkb:VIPL(gene name synonym)|uniprotkb:PSEC0028(orf name)|uniprotkb:UNQ368/PRO704(orf name)|uniprotkb:LMAN2L(gene name)|psi-mi:LMAN2L(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_001135764.1|refseq:NP_110432.1|refseq:NP_001309279.1|refseq:NP_001309280.1|refseq:NP_001309283.1|refseq:NP_001309276.1|refseq:NP_001309275.1|ensembl:ENSG00000114988(gene)|ensembl:ENST00000264963(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0046872"(metal ion binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|reactome:R-HSA-204005|reactome:R-HSA-5694530 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:sXVInY7CJsVQIeO5FWJsDBWqQak9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9BYC5 intact:EBI-25754632 intact:EBI-2869363|uniprotkb:Q9P2U6|uniprotkb:Q9P2U5|uniprotkb:O00235|uniprotkb:Q9BYC6|uniprotkb:B4DFS7|uniprotkb:G3V5N0|uniprotkb:Q8IUA5|ensembl:ENSP00000353910|ensembl:ENSP00000501213|ensembl:ENSP00000378087 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:fut8_human(display_long)|uniprotkb:FUT8(gene name)|psi-mi:FUT8(display_short)|uniprotkb:Fucosyltransferase 8(gene name synonym)|uniprotkb:"GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase"(gene name synonym)|uniprotkb:GDP-fucose--glycoprotein fucosyltransferase(gene name synonym)|uniprotkb:Glycoprotein 6-alpha-L-fucosyltransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_004471.4|refseq:NP_835368.1|refseq:NP_835369.1|ensembl:ENSG00000033170(gene)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:6VLE|go:"GO:1900407"(regulation of cellular response to oxidative stress)|interpro:IPR001452(Src homology-3)|rcsb pdb:6X5H|interpro:IPR015827("Alpha-(1,6)-fucosyltransferase, eukaryotic type")|interpro:IPR027350|interpro:IPR035653|interpro:IPR036028|mint:Q9BYC5|rcsb pdb:2DE0|rcsb pdb:6VLD|rcsb pdb:6X5R|rcsb pdb:6X5S|rcsb pdb:6X5T|rcsb pdb:6X5U|reactome:R-HSA-9694548|reactome:R-HSA-975578|ensembl:ENST00000360689(transcript)|ensembl:ENST00000394586(transcript)|ensembl:ENST00000673929(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008424"(glycoprotein 6-alpha-L-fucosyltransferase activity)|go:"GO:0009312"(oligosaccharide biosynthetic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033578"(protein glycosylation in Golgi)|go:"GO:0036071"(N-glycan fucosylation)|go:"GO:0042355"(L-fucose catabolic process)|go:"GO:0043112"(receptor metabolic process)|go:"GO:0046368"(GDP-L-fucose metabolic process)|go:"GO:0046921"("alpha-(1->6)-fucosyltransferase activity") - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:4ExQD5i1NzMB4ZN+jMDAgEDfXmg9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9BV40 intact:EBI-25754632 intact:EBI-727028|uniprotkb:O60625|uniprotkb:Q53SP9|uniprotkb:Q6IB09|ensembl:ENSP00000263864 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:vamp8_human(display_long)|uniprotkb:Endobrevin(gene name synonym)|uniprotkb:VAMP8(gene name)|psi-mi:VAMP8(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_003752.2|ensembl:ENSG00000118640(gene)|ensembl:ENST00000263864(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070254"(mucus secretion)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098594"(mucin granule)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903531"(negative regulation of secretion by cell)|go:"GO:1903595"(positive regulation of histamine secretion by mast cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR042855|mint:Q9BV40|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-1236974|reactome:R-HSA-199992|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|dip:DIP-40358N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:DW/t33n6NkBelQt6H1QS5hUY5+E9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q9BSJ2 intact:EBI-25754632 intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q96EC8 intact:EBI-25754632 intact:EBI-751210|uniprotkb:Q5JP08|uniprotkb:B4E1U7|uniprotkb:G5E997|ensembl:ENSP00000417573 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:yipf6_human(display_long)|uniprotkb:YIP1 family member 6(gene name synonym)|uniprotkb:YIPF6(gene name)|psi-mi:YIPF6(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_776195.2|refseq:NP_001182143.1|ensembl:ENSG00000181704(gene)|ensembl:ENST00000462683(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0060576"(intestinal epithelial cell development)|interpro:IPR006977(Yip1 domain)|mint:Q96EC8|reactome:R-HSA-432722 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:mfHkmdPyX5lK/euzg8v1Ydikf5w9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q92616 intact:EBI-25754632 intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q8TEM1 intact:EBI-25754632 intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q8NDZ4 intact:EBI-25754632 intact:EBI-20736890|ensembl:ENSP00000320081|uniprotkb:B2RCF2|uniprotkb:B7Z1W3 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:dik2a_human(display_long)|uniprotkb:DIPK2A(gene name)|psi-mi:DIPK2A(display_short)|uniprotkb:C3orf58(gene name synonym)|uniprotkb:DIA1(gene name synonym)|uniprotkb:Deleted in autism protein 1(gene name synonym)|uniprotkb:Golgi Protein of 49 kDa(gene name synonym)|uniprotkb:Hypoxia and AKT-induced stem cell factor(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 ensembl:ENSG00000181744(gene)|ensembl:ENST00000315691(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:1900020"(positive regulation of protein kinase C activity)|interpro:IPR020519|interpro:IPR022049|mint:Q8NDZ4|refseq:NP_001127942.1|refseq:NP_775823.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:9H/H8VQjfcpP0eOsFCaBuFEmiwY9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q6P3X3 intact:EBI-25754632 intact:EBI-1057046|uniprotkb:A6NKJ0|uniprotkb:Q96SS5|uniprotkb:Q9BVF1|uniprotkb:Q9NWR4|uniprotkb:Q9NXG4|ensembl:ENSP00000313953 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ttc27_human(display_long)|uniprotkb:TTC27(gene name)|psi-mi:TTC27(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_001180438.1|refseq:NP_060205.3|ensembl:ENSG00000018699(gene)|ensembl:ENST00000317907(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR044244|mint:Q6P3X3 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:LvE8UTgFaNjAZEkxCnmPTr/YP+Q9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:Q68DH5 intact:EBI-25754632 intact:EBI-20858131|ensembl:ENSP00000296603|uniprotkb:B3KRB6|uniprotkb:Q9NTC7 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:lmbd2_human(display_long)|uniprotkb:LMBRD2(gene name)|psi-mi:LMBRD2(display_short)|uniprotkb:LMBR1 domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 ensembl:ENSG00000164187(gene)|ensembl:ENST00000296603(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071875"(adrenergic receptor signaling pathway)|interpro:IPR006876(LMBR1-like conserved region)|mint:Q68DH5|refseq:NP_001007528.1|refseq:XP_011512464.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:q2WB24Dd8SLHl38AcRDvDE/k8zs9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:O95674 intact:EBI-25754632 intact:EBI-3913685|uniprotkb:Q5TDY5|uniprotkb:Q5TDY3|uniprotkb:Q5TDY2|uniprotkb:Q9NTT2|uniprotkb:Q9BYK5|uniprotkb:Q5TDY4|uniprotkb:D3DW04|uniprotkb:B2RDC6|ensembl:ENSP00000419879 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:cds2_human(display_long)|uniprotkb:CDS2(gene name)|psi-mi:CDS2(display_short)|uniprotkb:CDP-DAG synthase 2(gene name synonym)|uniprotkb:CDP-DG synthase 2(gene name synonym)|uniprotkb:CDP-diacylglycerol synthase 2(gene name synonym)|uniprotkb:CDP-diglyceride pyrophosphorylase 2(gene name synonym)|uniprotkb:CDP-diglyceride synthase 2(gene name synonym)|uniprotkb:"CTP:phosphatidate cytidylyltransferase 2"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_003809.1|ensembl:ENSG00000101290(gene)|ensembl:ENST00000460006(transcript)|go:"GO:0004605"(phosphatidate cytidylyltransferase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR000374(Phosphatidate cytidylyltransferase)|interpro:IPR016720(Phosphatidate cytidylyltransferase, eukaryota)|mint:O95674|reactome:R-HSA-1483148 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:tCRLIDMiesBx7QPKIycdX3Igz589606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7A1 uniprotkb:O94822 intact:EBI-25754632 intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846 psi-mi:vme1_mers1(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374565|imex:IM-28441-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|interpro:IPR044363 refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:Gvnkr2J8xV6cbINp+dr7rYOx1x01263720 rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606 rigid:cm+y2eN1qrBBZVM9DqwRBeo0AWQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V7 uniprotkb:Q15435 intact:EBI-25592177 intact:EBI-1024281|uniprotkb:Q9UQE5|uniprotkb:Q9UQE6|uniprotkb:Q9Y6K4|ensembl:ENSP00000234038|uniprotkb:B4DFD4|ensembl:ENSP00000385657|uniprotkb:B5MCY6 psi-mi:ncap_mers1(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:6(orf name) psi-mi:pp1r7_human(display_long)|uniprotkb:Protein phosphatase 1 regulatory subunit 22(gene name synonym)|uniprotkb:PPP1R7(gene name)|psi-mi:PPP1R7(display_short)|uniprotkb:SDS22(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374587|imex:IM-28441-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|rcsb pdb:6LZ6|rcsb pdb:6LZ8|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|rcsb pdb:6KL2|rcsb pdb:6KL5|rcsb pdb:6KL6|interpro:IPR044344|interpro:IPR044345 ensembl:ENSG00000115685(gene)|refseq:NP_002703.1|ensembl:ENST00000234038(transcript)|ensembl:ENST00000407025(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|rcsb pdb:6HKW|rcsb pdb:6MKY|rcsb pdb:6OBN|rcsb pdb:6OBP|refseq:NP_001269338.1|refseq:NP_001269339.1|refseq:NP_001269340.1|refseq:NP_001269341.1|refseq:NP_001269342.1|refseq:NP_001269343.1|dip:DIP-1005N - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:uPQmY5drwpOlo62BVox6DsftLlc1263720 rogid:HKHhTMtEgPpOdf/lS59bZAOrDjk9606 rigid:Xvt7R/tVXxi+Q1xkaiJFwKQdLGc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V7 uniprotkb:P68400 intact:EBI-25592177 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:ncap_mers1(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:6(orf name) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374587|imex:IM-28441-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|rcsb pdb:6LZ6|rcsb pdb:6LZ8|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|rcsb pdb:6KL2|rcsb pdb:6KL5|rcsb pdb:6KL6|interpro:IPR044344|interpro:IPR044345 rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:uPQmY5drwpOlo62BVox6DsftLlc1263720 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:Xvt7R/tVXxi+Q1xkaiJFwKQdLGc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V7 uniprotkb:P19784 intact:EBI-25592177 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:ncap_mers1(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:6(orf name) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374587|imex:IM-28441-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|rcsb pdb:6LZ6|rcsb pdb:6LZ8|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|rcsb pdb:6KL2|rcsb pdb:6KL5|rcsb pdb:6KL6|interpro:IPR044344|interpro:IPR044345 refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:uPQmY5drwpOlo62BVox6DsftLlc1263720 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:Xvt7R/tVXxi+Q1xkaiJFwKQdLGc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N5Q8 uniprotkb:P09382 intact:EBI-25474996 intact:EBI-1048875|uniprotkb:B2R5E8|uniprotkb:Q9UDK5|ensembl:ENSP00000215909 psi-mi:spike_mers1(display_long)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:3(orf name)|uniprotkb:S(gene name)|psi-mi:S(display_short) psi-mi:leg1_human(display_long)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:HPL(gene name synonym)|uniprotkb:HBL(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM12(gene name synonym)|uniprotkb:LGALS1(gene name)|psi-mi:LGALS1(display_short)|uniprotkb:Lactose-binding lectin 1(gene name synonym)|uniprotkb:14 kDa laminin-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374595|imex:IM-28441-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043002|interpro:IPR044873|interpro:IPR044874|rcsb pdb:7M55|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR043473|rcsb pdb:7C02|interpro:IPR044337|interpro:IPR044376|rcsb pdb:6J11|rcsb pdb:6J2J|rcsb pdb:4L72|rcsb pdb:4MOD|rcsb pdb:4XAK|rcsb pdb:4ZPT|rcsb pdb:4ZPV|rcsb pdb:4ZPW|rcsb pdb:5GMQ|rcsb pdb:5GR7|rcsb pdb:5GSB|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5VYH|rcsb pdb:5W9H|rcsb pdb:5W9I|rcsb pdb:5W9J|rcsb pdb:5W9K|rcsb pdb:5W9L|rcsb pdb:5W9M|rcsb pdb:5W9N|rcsb pdb:5W9O|rcsb pdb:5W9P|rcsb pdb:5X4R|rcsb pdb:5X59|rcsb pdb:5X5C|rcsb pdb:5X5F|rcsb pdb:5YY5|rcsb pdb:5ZVK|rcsb pdb:5ZXV|rcsb pdb:6C6Y|rcsb pdb:6C6Z|interpro:IPR042578|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR036326|rcsb pdb:6PXH|interpro:IPR032500|interpro:IPR043607|interpro:IPR043614|rcsb pdb:6L8Q|rcsb pdb:6WAR refseq:NP_002296.1|ensembl:ENST00000215909(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|ensembl:ENSG00000100097(gene)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P09382|rcsb pdb:1GZW|rcsb pdb:1W6M|rcsb pdb:1W6N|rcsb pdb:1W6O|rcsb pdb:1W6P|rcsb pdb:1W6Q|rcsb pdb:2KM2|rcsb pdb:2ZKN|rcsb pdb:3OY8|rcsb pdb:3OYW|rcsb pdb:3T2T|rcsb pdb:3W58|rcsb pdb:3W59|rcsb pdb:4Q1P|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4Q1R|rcsb pdb:4Q26|rcsb pdb:4Q27|rcsb pdb:4Q2F|rcsb pdb:4XBL|rcsb pdb:4Y1U|rcsb pdb:4Y1V|rcsb pdb:4Y1X|rcsb pdb:4Y1Y|rcsb pdb:4Y1Z|rcsb pdb:4Y20|rcsb pdb:4Y22|rcsb pdb:4Y24|rcsb pdb:5MWT|rcsb pdb:5MWX|rcsb pdb:6B94|rcsb pdb:6F83|rcsb pdb:6M5Y|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-46153N - - - figure legend:Table 2, no 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:6bq0dCMRZIrh+JDav4MxdGChyEg1263720 rogid:Sov3RfY2NOjdjuvdFlEd/vaNTMY9606 rigid:SFPgUjKDY/CLgRH2kHaCS6yTQKg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422448 uniprotkb:Q9C026 intact:EBI-25594384 intact:EBI-720828|ensembl:ENSP00000298355|uniprotkb:Q92557|uniprotkb:Q96D24|uniprotkb:Q96NI4|uniprotkb:Q9C025|uniprotkb:Q9C027|uniprotkb:D3DSB7|uniprotkb:D3DSB8 psi-mi:k9n7c7-pro_0000422448(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:trim9_human(display_long)|uniprotkb:RING finger protein 91(gene name synonym)|uniprotkb:TRIM9(gene name)|psi-mi:TRIM9(display_short)|uniprotkb:KIAA0282(gene name synonym)|uniprotkb:RNF91(gene name synonym)|uniprotkb:Tripartite motif-containing protein 9(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM9(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374603|imex:IM-28441-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000100505(gene)|ensembl:ENST00000298355(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR036116|interpro:IPR043136|rcsb pdb:2DB8|rcsb pdb:7B2S|reactome:R-HSA-983168|refseq:XP_011534691.1|refseq:NP_055978.4|refseq:NP_443210.1|refseq:XP_016876434.1 - chain-seq-start:4238|chain-seq-end:4377 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:+P46ulRZ4DcqWX5MiCofIcaUyCs1263720 rogid:cWf6NobHVvKBKNqclJsLeoJKfMw9606 rigid:OYYBbvuSIkEtz4jQR+fHYdQBPQs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422448 uniprotkb:Q9BZH6 intact:EBI-25594384 intact:EBI-2009923|uniprotkb:Q5VWA1|uniprotkb:Q9P2J6|ensembl:ENSP00000263461 psi-mi:k9n7c7-pro_0000422448(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wdr11_human(display_long)|uniprotkb:WDR11(gene name)|psi-mi:WDR11(display_short)|uniprotkb:KIAA1351(gene name synonym)|uniprotkb:BRWD2(gene name synonym)|uniprotkb:WDR15(gene name synonym)|uniprotkb:Bromodomain and WD repeat-containing protein 2(gene name synonym)|uniprotkb:WD repeat-containing protein 15(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374603|imex:IM-28441-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_060587.8|ensembl:ENSG00000120008(gene)|ensembl:ENST00000263461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0099041"(vesicle tethering to Golgi)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039694|mint:Q9BZH6|reactome:R-HSA-9013407 - chain-seq-start:4238|chain-seq-end:4377 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:+P46ulRZ4DcqWX5MiCofIcaUyCs1263720 rogid:Kl337t8mCHvvkb8oi0z8Ohl72a09606 rigid:OYYBbvuSIkEtz4jQR+fHYdQBPQs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422448 uniprotkb:P28330 intact:EBI-25594384 intact:EBI-12059321|ensembl:ENSP00000233710|uniprotkb:B2R8T3|uniprotkb:Q8IUN8 psi-mi:k9n7c7-pro_0000422448(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:acadl_human(display_long)|uniprotkb:ACADL(gene name)|psi-mi:ACADL(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374603|imex:IM-28441-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034179|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77310|go:"GO:0090181"(regulation of cholesterol metabolic process)|ensembl:ENSG00000115361(gene)|ensembl:ENST00000233710(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016401"(palmitoyl-CoA oxidase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042413"(carnitine catabolic process)|go:"GO:0042758"(long-chain fatty acid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_001599.1 - chain-seq-start:4238|chain-seq-end:4377 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:+P46ulRZ4DcqWX5MiCofIcaUyCs1263720 rogid:0R1u+zewK9TK3F2oKQZXEh3Y16E9606 rigid:OYYBbvuSIkEtz4jQR+fHYdQBPQs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422439 uniprotkb:Q05516 intact:EBI-26374609 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 psi-mi:k9n7c7-pro_0000422439(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374629|imex:IM-28441-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N - chain-seq-start:1|chain-seq-end:193 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:adHwE+81k4ZMdG+FABtYf/oJ90k1263720 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 rigid:hmMItUKe2cvuiz5/HGESoiHd+uA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422439 uniprotkb:P42345 intact:EBI-26374609 intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074 psi-mi:k9n7c7-pro_0000422439(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374629|imex:IM-28441-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N - chain-seq-start:1|chain-seq-end:193 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:adHwE+81k4ZMdG+FABtYf/oJ90k1263720 rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606 rigid:hmMItUKe2cvuiz5/HGESoiHd+uA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422439 uniprotkb:P40763 intact:EBI-26374609 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:k9n7c7-pro_0000422439(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374629|imex:IM-28441-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N - chain-seq-start:1|chain-seq-end:193 crc64:6C00632211C8012D figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:adHwE+81k4ZMdG+FABtYf/oJ90k1263720 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rigid:hmMItUKe2cvuiz5/HGESoiHd+uA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422439 uniprotkb:O60220 intact:EBI-26374609 intact:EBI-1049822|uniprotkb:Q6IRW6|uniprotkb:B2R5A6|ensembl:ENSP00000361993 psi-mi:k9n7c7-pro_0000422439(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tim8a_human(display_long)|uniprotkb:Deafness dystonia protein 1(gene name synonym)|uniprotkb:X-linked deafness dystonia protein(gene name synonym)|uniprotkb:TIMM8A(gene name)|psi-mi:TIMM8A(display_short)|uniprotkb:DDP(gene name synonym)|uniprotkb:DDP1(gene name synonym)|uniprotkb:TIM8A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374629|imex:IM-28441-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_004076.1|reactome:R-HSA-1268020|ensembl:ENSG00000126953(gene)|ensembl:ENST00000372902(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007399"(nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:O60220 - chain-seq-start:1|chain-seq-end:193 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:adHwE+81k4ZMdG+FABtYf/oJ90k1263720 rogid:v01DxxXFU24eNjL3zVBvqQP9zA49606 rigid:hmMItUKe2cvuiz5/HGESoiHd+uA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N638-PRO_0000422464 uniprotkb:O14734 intact:EBI-26366289 intact:EBI-1237371|uniprotkb:O15261|uniprotkb:Q17RX4|ensembl:ENSP00000217455 psi-mi:k9n638-pro_0000422464(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym)|uniprotkb:1a(orf name) psi-mi:acot8_human(display_long)|uniprotkb:ACOT8(gene name)|psi-mi:ACOT8(display_short)|uniprotkb:ACTEIII(gene name synonym)|uniprotkb:PTE1(gene name synonym)|uniprotkb:Choloyl-coenzyme A thioesterase(gene name synonym)|uniprotkb:Peroxisomal acyl-coenzyme A thioester hydrolase 1(gene name synonym)|uniprotkb:Peroxisomal long-chain acyl-CoA thioesterase 1(gene name synonym)|uniprotkb:HIV-Nef-associated acyl-CoA thioesterase(gene name synonym)|uniprotkb:Thioesterase II(gene name synonym)|uniprotkb:Peroxisomal acyl-CoA thioesterase 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374663|imex:IM-28441-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25618448(chain-parent) refseq:NP_005460.2|dip:DIP-38179N|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043649"(dicarboxylic acid catabolic process)|go:"GO:0044466"(glutaryl-CoA hydrolase activity)|go:"GO:0045225"(negative regulation of CD4 production)|go:"GO:0047603"(acetoacetyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0047994"(hydroxymethylglutaryl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0052815"(medium-chain acyl-CoA hydrolase activity)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|interpro:IPR003703(Acyl-CoA thioesterase)|interpro:IPR029069|interpro:IPR042171|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|ensembl:ENSG00000101473(gene)|ensembl:ENST00000217455(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0004778"(succinyl-CoA hydrolase activity)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016289"(CoA hydrolase activity)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016559"(peroxisome fission)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0033882"(choloyl-CoA hydrolase activity) - chain-seq-start:4378|chain-seq-end:4391 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:67yoojr7PhCy9COVfB/eyMhIuqo1263720 rogid:Q8Y3l4ysgKPMi3mJU2/g8mVxWE09606 rigid:EozuGul83uWCThzu7QTrkI8Rl14 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:P17612 intact:EBI-26429470 intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q9UPN4 intact:EBI-26429470 intact:EBI-2558372|uniprotkb:B2RN11|uniprotkb:Q96F50|uniprotkb:A6NHI8|ensembl:ENSP00000269392 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cp131_human(display_long)|uniprotkb:CEP131(gene name)|psi-mi:CEP131(display_short)|uniprotkb:5-azacytidine-induced protein 1(gene name synonym)|uniprotkb:AZI1(gene name synonym)|uniprotkb:KIAA1118(gene name synonym)|uniprotkb:Pre-acrosome localization protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001009811.2|refseq:NP_055799.2|refseq:NP_001306157.1|ensembl:ENSG00000141577(gene)|ensembl:ENST00000269392(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120212"(sperm head-tail coupling apparatus)|go:"GO:1905198"(manchette assembly)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990953"(intramanchette transport)|interpro:IPR030465|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005814"(centriole)|dip:DIP-56658N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:qcnzG6vfogSEappaH9nv7P3kSoQ9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:P35579 intact:EBI-26429470 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q9Y2I6 intact:EBI-26429470 intact:EBI-719716|uniprotkb:A6NJN0|uniprotkb:B3V9H6|uniprotkb:B7Z1V8|uniprotkb:Q8NE38|uniprotkb:Q9NQE3|intact:EBI-741715|uniprotkb:Q5JYP0|ensembl:ENSP00000278886 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ninl_human(display_long)|uniprotkb:NINL(gene name)|psi-mi:NINL(display_short)|uniprotkb:KIAA0980(gene name synonym)|uniprotkb:NLP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_079452.3|refseq:NP_001305155.1|ensembl:ENSG00000101004(gene)|ensembl:ENST00000278886(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:NAG+S5iboAG+mjX9ISJ05gY2lJY9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q9UNZ2 intact:EBI-26429470 intact:EBI-721577|uniprotkb:Q7Z533|uniprotkb:Q9H102|uniprotkb:Q9NVL9|uniprotkb:Q9UI06|uniprotkb:Q5JXA5|uniprotkb:B2RD74|uniprotkb:Q5JXA4|uniprotkb:A2A2L1|ensembl:ENSP00000216879 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:nsf1c_human(display_long)|uniprotkb:p97 cofactor p47(gene name synonym)|uniprotkb:NSFL1C(gene name)|psi-mi:NSFL1C(display_short)|uniprotkb:UBXN2C(gene name synonym)|uniprotkb:UBX domain-containing protein 2C(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001193665.1|refseq:NP_057227.2|refseq:NP_061327.2|dip:DIP-39611N|refseq:XP_006723657.1|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0051117"(ATPase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1990730"(VCP-NSFL1C complex)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR012989(SEP)|interpro:IPR029071|interpro:IPR036241|mint:Q9UNZ2|rcsb pdb:1SS6|reactome:R-HSA-9013407|go:"GO:0000045"(autophagosome assembly)|ensembl:ENSG00000088833(gene)|ensembl:ENST00000216879(transcript) - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:LhK56TmbnfHvffJ2WUFlJJepje89606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q9C0B0 intact:EBI-26429470 intact:EBI-949156|intact:EBI-28969974|ensembl:ENSP00000464893 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:unk_human(display_long)|uniprotkb:Zinc finger CCCH domain-containing protein 5(gene name synonym)|uniprotkb:UNK(gene name)|psi-mi:UNK(display_short)|uniprotkb:KIAA1753(gene name synonym)|uniprotkb:ZC3HDC5(gene name synonym)|uniprotkb:ZC3H5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000132478(gene)|ensembl:ENST00000589666(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:1905538"(polysome binding)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR040594|ensembl:ENSP00000464893|refseq:NP_001073888.2 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:A1jCk45USLGOYBrrlWldqHAwWww9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q9BV73 intact:EBI-26429470 intact:EBI-1053100|uniprotkb:O14812|uniprotkb:O60588|uniprotkb:Q9H450|uniprotkb:E1P5Q3|ensembl:ENSP00000380661 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cp250_human(display_long)|uniprotkb:Centrosomal protein 2(gene name synonym)|uniprotkb:Centrosomal Nek2-associated protein 1(gene name synonym)|uniprotkb:CEP250(gene name)|psi-mi:CEP250(display_short)|uniprotkb:CEP2(gene name synonym)|uniprotkb:CNAP1(gene name synonym)|uniprotkb:250 kDa centrosomal protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_009117.2|dip:DIP-39406N|refseq:NP_001305148.1|refseq:XP_005260319.1|refseq:XP_006723753.1|refseq:XP_006723754.1|refseq:XP_006723755.1|refseq:XP_006723756.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|mint:Q9BV73|rcsb pdb:6OQA|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000126001(gene)|ensembl:ENST00000397527(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060271"(cilium assembly) - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:We+5inOR7merXjzOl/vRehewlFA9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q9BQS8 intact:EBI-26429470 intact:EBI-2869338|uniprotkb:Q96IV5|uniprotkb:Q3MJE6|uniprotkb:Q8TEF9|uniprotkb:Q86T41|uniprotkb:Q9H8P9|uniprotkb:Q86TB1|uniprotkb:B7ZKT7|ensembl:ENSP00000296137 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:fyco1_human(display_long)|uniprotkb:FYCO1(gene name)|psi-mi:FYCO1(display_short)|uniprotkb:ZFYVE7(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:XP_011532413.1|refseq:XP_006713396.1|refseq:XP_006713397.1|refseq:NP_078789.2|ensembl:ENSG00000163820(gene)|ensembl:ENST00000296137(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR004012(RUN)|interpro:IPR009038(GOLD)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR036598|interpro:IPR037213|interpro:IPR042654|mint:Q9BQS8|rcsb pdb:5CX3|rcsb pdb:5D94|rcsb pdb:7BQI|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|dip:DIP-60600N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:/iOQiItN7ljXD08DN8DvQ1m6t0E9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q99996 intact:EBI-26429470 intact:EBI-1048311|uniprotkb:O14869|uniprotkb:O43355|uniprotkb:O94895|uniprotkb:Q75N20|uniprotkb:Q9UQH3|uniprotkb:Q9UQQ4|uniprotkb:Q9Y6B8|uniprotkb:A4D1F0|uniprotkb:Q9Y6Y2|uniprotkb:A4D1F2|uniprotkb:A4D1F4|ensembl:ENSP00000348573 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:akap9_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)|uniprotkb:A-kinase anchor protein 450 kDa(gene name synonym)|uniprotkb:A-kinase anchor protein 350 kDa(gene name synonym)|uniprotkb:AKAP 120-like protein(gene name synonym)|uniprotkb:Protein hyperion(gene name synonym)|uniprotkb:Protein yotiao(gene name synonym)|uniprotkb:Centrosome- and Golgi-localized PKN-associated protein(gene name synonym)|uniprotkb:AKAP9(gene name)|psi-mi:AKAP9(display_short)|uniprotkb:AKAP350(gene name synonym)|uniprotkb:AKAP450(gene name synonym)|uniprotkb:KIAA0803(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_005742.4|refseq:NP_671714.1|ensembl:ENSG00000127914(gene)|ensembl:ENST00000356239(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044307"(dendritic branch)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR005539(ELK)|interpro:IPR019528|interpro:IPR028745|mint:Q99996|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5576890|reactome:R-HSA-5576893|reactome:R-HSA-5620912|reactome:R-HSA-6802952|reactome:R-HSA-8854518|ensembl:ENSP00000348573|ensembl:ENST00000680766|ensembl:ENSP00000505204|dip:DIP-29942N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:LQUNbTHUgEsjayFEZvczC4e90Nw9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q96SN8 intact:EBI-26429470 intact:EBI-308374|uniprotkb:Q7Z3L4|uniprotkb:Q7Z3U1|uniprotkb:Q7Z7I6|uniprotkb:Q9BSW0|uniprotkb:Q9H6J6|uniprotkb:Q9HCD9|uniprotkb:Q9NV90|uniprotkb:Q9UIW9|uniprotkb:Q5JV18|ensembl:ENSP00000343818 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ck5p2_human(display_long)|uniprotkb:CDK5RAP2(gene name)|psi-mi:CDK5RAP2(display_short)|uniprotkb:KIAA1633(gene name synonym)|uniprotkb:CDK5 activator-binding protein C48(gene name synonym)|uniprotkb:Centrosome-associated protein 215(gene name synonym)|uniprotkb:CEP215(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001011649.1|ensembl:ENSG00000136861(gene)|ensembl:ENST00000349780(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR012943(Spindle associated)|mint:Q96SN8|rcsb pdb:6X0V|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_060719.4|refseq:NP_001258968.1|refseq:XP_006717245.1|dip:DIP-31632N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:/XamYFvD5N/npIkOGnLQkZzmBnU9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q8TD10 intact:EBI-26429470 intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q8NDN9 intact:EBI-26429470 intact:EBI-2811558|uniprotkb:Q969U9|intact:EBI-3044072|uniprotkb:Q8IY29|ensembl:ENSP00000258646|ensembl:ENSP00000367552 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:rcbt1_human(display_long)|uniprotkb:RCBTB1(gene name)|psi-mi:RCBTB1(display_short)|uniprotkb:CLLD7(gene name synonym)|uniprotkb:E4.5(gene name synonym)|uniprotkb:Chronic lymphocytic leukemia deletion region gene 7 protein(gene name synonym)|uniprotkb:Regulator of chromosome condensation and BTB domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:XP_011533435.1|refseq:XP_011533436.1|refseq:NP_060661.3|ensembl:ENSG00000136144(gene)|ensembl:ENST00000258646(transcript)|ensembl:ENST00000378302(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|refseq:XP_005266498.1 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:qlFRfKV0PffERWU2HnbL6M64qa09606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q8N4C6 intact:EBI-26429470 intact:EBI-1164022|uniprotkb:Q6P0P6|uniprotkb:Q9BWU6|uniprotkb:Q9C012|uniprotkb:Q9C013|uniprotkb:Q9C014|uniprotkb:Q9H5I6|uniprotkb:Q9HAT7|uniprotkb:Q9HBY5|uniprotkb:Q9HCK7|uniprotkb:Q9UH61|uniprotkb:A6NDB8|uniprotkb:B7WPA3|uniprotkb:C9JSB6|uniprotkb:C9JSG2|uniprotkb:C9JXL2|ensembl:ENSP00000371472|uniprotkb:Q5BKU3 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:nin_human(display_long)|uniprotkb:Glycogen synthase kinase 3 beta-interacting protein(gene name synonym)|uniprotkb:NIN(gene name)|psi-mi:NIN(display_short)|uniprotkb:KIAA1565(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:XP_011535125.1|ensembl:ENSG00000100503(gene)|ensembl:ENST00000382041(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|refseq:NP_057434.4|refseq:NP_065972.3|refseq:NP_891989.2|refseq:NP_891991.1|go:"GO:0005814"(centriole)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019900"(kinase binding)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045177"(apical part of cell)|go:"GO:0048668"(collateral sprouting)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR029664|mint:Q8N4C6|go:"GO:0034454"(microtubule anchoring at centrosome) - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:ZvO0amOxGf+HZIxnXTYCqpnzTjw9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q8IWJ2 intact:EBI-26429470 intact:EBI-1645320|uniprotkb:O15045|uniprotkb:Q4ZG46|uniprotkb:Q8TDH3|uniprotkb:Q9H2G8|uniprotkb:A6H8X8|intact:EBI-1645335|intact:EBI-28984280|ensembl:ENSP00000307939 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:gcc2_human(display_long)|uniprotkb:GCC2(gene name)|psi-mi:GCC2(display_short)|uniprotkb:KIAA0336(gene name synonym)|uniprotkb:RANBP2L4(gene name synonym)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Ran-binding protein 2-like 4(gene name synonym)|uniprotkb:CTCL tumor antigen se1-1(gene name synonym)|uniprotkb:CLL-associated antigen KW-11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-53(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_852118.1|refseq:XP_006712934.1|ensembl:ENSP00000307939|ensembl:ENST00000482325|ensembl:ENSP00000419969|ensembl:ENSG00000135968(gene)|ensembl:ENST00000309863(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0016020"(membrane)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034499"(late endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0070861"(regulation of protein exit from endoplasmic reticulum)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR000237(GRIP)|interpro:IPR032023|rcsb pdb:3BBP|reactome:R-HSA-6811440 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:YeL/V7QABi3DbamH+qE6WfFLAco9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q8IUD2 intact:EBI-26429470 intact:EBI-1044755|uniprotkb:Q6NVK2|uniprotkb:Q8IUD3|uniprotkb:Q8IUD4|uniprotkb:Q8IUD5|uniprotkb:Q8NAS1|uniprotkb:Q9NXN5|uniprotkb:Q9UIK7|uniprotkb:Q9UPS1|intact:EBI-3645200|uniprotkb:A7E295|ensembl:ENSP00000354158|ensembl:ENSP00000468263|uniprotkb:D3DUP7|uniprotkb:D3DUP8|uniprotkb:A2RU77 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:rb6i2_human(display_long)|uniprotkb:Rab6-interacting protein 2(gene name synonym)|uniprotkb:ERC1(gene name)|psi-mi:ERC1(display_short)|uniprotkb:ELKS(gene name synonym)|uniprotkb:KIAA1081(gene name synonym)|uniprotkb:RAB6IP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_829883.1|refseq:NP_829884.1|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0015031"(protein transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0007275"(multicellular organism development)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR019018|interpro:IPR019323|interpro:IPR037245|ensembl:ENSG00000082805(gene)|ensembl:ENST00000360905(transcript)|ensembl:ENST00000589028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|refseq:XP_016874553.1|refseq:XP_016874556.1|refseq:XP_011519243.1 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:0W5DM0QbKuWdMW4T+pJKPT7pKgA9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q66GS9 intact:EBI-26429470 intact:EBI-1046993|uniprotkb:O75130|uniprotkb:Q9H8H7|uniprotkb:B2RMY0|uniprotkb:Q58F25|ensembl:ENSP00000257287|intact:EBI-1058323 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cp135_human(display_long)|uniprotkb:Centrosomal protein 4(gene name synonym)|uniprotkb:CEP135(gene name)|psi-mi:CEP135(display_short)|uniprotkb:CEP4(gene name synonym)|uniprotkb:KIAA0635(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_079285.2|rcsb pdb:5FCN|rcsb pdb:5NG4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|ensembl:ENSG00000174799(gene)|ensembl:ENST00000257287(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007099"(centriole replication)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR026732|mint:Q66GS9|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-50271N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:x/sbJVIQUS2zD/l2SQsmV5HwKP89606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q5VU43 intact:EBI-26429470 intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q16881 intact:EBI-26429470 intact:EBI-716617|uniprotkb:Q6FI31|uniprotkb:Q6VB40|uniprotkb:Q6VB41|uniprotkb:Q6VB42|uniprotkb:Q6VBP2|uniprotkb:Q6VBP3|uniprotkb:Q6VBP4|uniprotkb:Q6VBP5|uniprotkb:Q6VBP9|uniprotkb:Q6VBQ0|uniprotkb:Q6YNQ1|uniprotkb:Q8WVC8|uniprotkb:Q99475|uniprotkb:Q9UES8|uniprotkb:Q76P53|uniprotkb:Q7LA96|uniprotkb:Q9UH79|uniprotkb:B7Z1F4|uniprotkb:B7Z3Y8|uniprotkb:B7Z904|uniprotkb:E9PMY9|uniprotkb:F5H780|ensembl:ENSP00000434516 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:trxr1_human(display_long)|uniprotkb:KDRF(gene name synonym)|uniprotkb:Thioredoxin reductase TR1(gene name synonym)|uniprotkb:KM-102-derived reductase-like factor(gene name synonym)|uniprotkb:GRIM12(gene name synonym)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 12 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001087240.1|refseq:NP_003321.3|refseq:NP_877393.1|refseq:NP_877419.1|refseq:NP_877420.1|refseq:NP_001248374.1|refseq:NP_001248375.1|rcsb pdb:3QFA|rcsb pdb:3QFB|reactome:R-HSA-1989781|reactome:R-HSA-2408550|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5263617|reactome:R-HSA-5336415|reactome:R-HSA-5628897|ensembl:ENSG00000198431(gene)|ensembl:ENST00000525566(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|interpro:IPR036249|mint:Q16881|rcsb pdb:1W1C|rcsb pdb:2CFY|rcsb pdb:2J3N|rcsb pdb:2ZZ0|rcsb pdb:2ZZB|rcsb pdb:2ZZC - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:0CrcaHgTDl4AIU4V2zXt3u9Pet89606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q15154 intact:EBI-26429470 intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q12965 intact:EBI-26429470 intact:EBI-4279548|uniprotkb:Q14778|ensembl:ENSP00000288235 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myo1e_human(display_long)|uniprotkb:Myosin-Ic(gene name synonym)|uniprotkb:MYO1E(gene name)|psi-mi:MYO1E(display_short)|uniprotkb:MYO1C(gene name synonym)|uniprotkb:Unconventional myosin 1E(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_004989.2|ensembl:ENSG00000157483(gene)|ensembl:ENST00000288235(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035507|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|mint:Q12965|ensembl:ENSP00000288235|dip:DIP-884N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:UyG3wKoRwL2Eaw9CM6561vld+PU9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q08379 intact:EBI-26429470 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:Q08378 intact:EBI-26429470 intact:EBI-355782|uniprotkb:O43241|uniprotkb:Q6P9C7|uniprotkb:Q86XW3|uniprotkb:Q8TDA9|uniprotkb:Q8WZA3|uniprotkb:A5PKX6|intact:EBI-28985028|ensembl:ENSP00000204726|ensembl:ENSP00000410378 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:goga3_human(display_long)|uniprotkb:GOLGA3(gene name)|psi-mi:GOLGA3(display_short)|uniprotkb:Golgin-160(gene name synonym)|uniprotkb:Golgi complex-associated protein of 170 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001166028.1|refseq:NP_005886.2|ensembl:ENSP00000204726|ensembl:ENSP00000410378|ensembl:ENST00000456883|ensembl:ENSP00000409303|ensembl:ENST00000545875|ensembl:ENSP00000442603|ensembl:ENSG00000090615(gene)|ensembl:ENST00000204726(transcript)|ensembl:ENST00000450791(transcript)|go:"GO:0045296"(cadherin binding)|go:"GO:0090498"(extrinsic component of Golgi membrane)|interpro:IPR033288|mint:Q08378|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9696270|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|refseq:XP_006719799.1|refseq:XP_006719800.1 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:7AjSzX3sUzfKpZkvdKDM0L//zYM9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:P67936 intact:EBI-26429470 intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:P49454 intact:EBI-26429470 intact:EBI-968343|ensembl:ENSP00000355922|uniprotkb:Q13171|uniprotkb:Q13246|uniprotkb:Q5VVM7|intact:EBI-2563723|intact:EBI-21028103 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cenpf_human(display_long)|uniprotkb:CENPF(gene name)|psi-mi:CENPF(display_short)|uniprotkb:Kinetochore protein CENPF(gene name synonym)|uniprotkb:Mitosin(gene name synonym)|uniprotkb:AH antigen(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000117724(gene)|ensembl:ENST00000366955(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0001822"(kidney development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0042493"|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR018302|interpro:IPR018463|interpro:IPR019513|interpro:IPR043513|mint:P49454|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-156711|refseq:NP_057427.3|refseq:XP_016855575.1 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:gPlJiOCF1/MAVT80oKwlQlLgluo9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:P31323 intact:EBI-26429470 intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:P14649 intact:EBI-26429470 intact:EBI-358570|ensembl:ENSP00000446643|ensembl:ENSP00000450385 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myl6b_human(display_long)|uniprotkb:MYL6B(gene name)|psi-mi:MYL6B(display_short)|uniprotkb:MLC1SA(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym)|uniprotkb:Myosin light chain 1 slow-twitch muscle A isoform(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001186558.1|refseq:NP_002466.1|ensembl:ENSG00000196465(gene)|ensembl:ENST00000550443(transcript)|ensembl:ENST00000553066(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|reactome:R-HSA-445355 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:S0/S5hUxfyyve1JDMojIggOSBb89606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:P13861 intact:EBI-26429470 intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:P09493 intact:EBI-26429470 intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1 - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422450 uniprotkb:O95613 intact:EBI-26429470 intact:EBI-530012|uniprotkb:O43152|uniprotkb:Q7Z7C9|intact:EBI-28971202|ensembl:ENSP00000352572 psi-mi:k9n7c7-pro_0000422450(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:pcnt_human(display_long)|uniprotkb:Pericentrin-B(gene name synonym)|uniprotkb:Kendrin(gene name synonym)|uniprotkb:PCNT(gene name)|psi-mi:PCNT(display_short)|uniprotkb:KIAA0402(gene name synonym)|uniprotkb:PCNT2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374676|imex:IM-28441-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSP00000352572|refseq:NP_006022.3|refseq:NP_001302458.1|ensembl:ENSG00000160299(gene)|ensembl:ENST00000359568(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR019528|interpro:IPR028745|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|dip:DIP-33829N - chain-seq-start:5311|chain-seq-end:5908 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:AlBuNr3lrwBlAXMyEZhWznYtzyc1263720 rogid:8YHnOQE3b77ocsel2oAdsqvE+js9606 rigid:gpNCs3bIRFrPljEvO3cDjJKdXwc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:Q92878 intact:EBI-25594390 intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50) - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:Q9NQX3 intact:EBI-25594390 intact:EBI-2371891|uniprotkb:Q9H4E9|uniprotkb:Q9P2G2|uniprotkb:Q96KU4|ensembl:ENSP00000312771 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:geph_human(display_long)|uniprotkb:GPHN(gene name)|psi-mi:GPHN(display_short)|uniprotkb:GPH(gene name synonym)|uniprotkb:KIAA1385(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001019389.1|refseq:NP_065857.1|dip:DIP-41076N|rcsb pdb:1JLJ|reactome:R-HSA-947581|interpro:IPR038987|ensembl:ENSG00000171723(gene)|ensembl:ENST00000315266(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0010038"(response to metal ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018315"(molybdenum incorporation into molybdenum-molybdopterin complex)|go:"GO:0030425"(dendrite)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0061598"(molybdopterin adenylyltransferase activity)|go:"GO:0061599"(molybdopterin molybdotransferase activity)|go:"GO:0072579"(glycine receptor clustering)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0099144"(anchored component of synaptic membrane)|go:"GO:0099572"(postsynaptic specialization)|go:"GO:0099634"(postsynaptic specialization membrane)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR008284(Molybdenum cofactor biosynthesis, conserved site)|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688 - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:iu4Nl7g9dOChbmYok/lo6kjW3pM9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:Q96EN8 intact:EBI-25594390 intact:EBI-1220583|uniprotkb:Q53GP5|uniprotkb:Q8N3A4|uniprotkb:Q9NWM7|ensembl:ENSP00000261326 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mocos_human(display_long)|uniprotkb:MOCOS(gene name)|psi-mi:MOCOS(display_short)|uniprotkb:Molybdenum cofactor sulfurtransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_060417.2|ensembl:ENSG00000075643(gene)|ensembl:ENST00000261326(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0008265"(Mo-molybdopterin cofactor sulfurase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0043545"(molybdopterin cofactor metabolic process)|go:"GO:0102867"(molybdenum cofactor sulfurtransferase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR028886|mint:Q96EN8|reactome:R-HSA-947581 - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:c1HZVYnnbRSW3olxYNYmtb3S8a09606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:Q5T9A4 intact:EBI-25594390 intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695 - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:2W52iPQhTBU2apShm8xhfenV1mU9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:Q5QP82 intact:EBI-25594390 intact:EBI-723230|uniprotkb:A4VCJ5|uniprotkb:Q32NE2|uniprotkb:Q96ET5|uniprotkb:Q9BTQ5|uniprotkb:Q9H5P6|uniprotkb:Q8N2Q5|ensembl:ENSP00000366953|intact:EBI-2559068 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dca10_human(display_long)|uniprotkb:DCAF10(gene name)|psi-mi:DCAF10(display_short)|uniprotkb:WDR32(gene name synonym)|uniprotkb:WD repeat-containing protein 32(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_077321.3|ensembl:ENSG00000122741(gene)|ensembl:ENST00000377724(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR039085|mint:Q5QP82|reactome:R-HSA-8951664|interpro:IPR001680(WD40 repeat)|refseq:NP_001273739.1|refseq:XP_005251634.1 - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:0mrMrjLK7HAJLVaAg/spKCEKOAo9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:P63151 intact:EBI-25594390 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:P49959 intact:EBI-25594390 intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:P30153 intact:EBI-25594390 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:P04637 intact:EBI-25594390 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422451 uniprotkb:O95071 intact:EBI-25594390 intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7 psi-mi:k9n7c7-pro_0000422451(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374745|imex:IM-28441-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N - chain-seq-start:5909|chain-seq-end:6432 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:h6Z4Ydarw7TLx9V8OruEqQ7k47I1263720 rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606 rigid:/iedWG7xRted030M+Smww43cbJg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422452 uniprotkb:A0A0B4J1Y9 intact:EBI-25592093 intact:EBI-25606848|ensembl:ENSP00000416201|ensembl:ENSP00000488019|uniprotkb:A0A087WW89 psi-mi:k9n7c7-pro_0000422452(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hv372_human(display_long)|uniprotkb:IGHV3-72(gene name)|psi-mi:IGHV3-72(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374774|imex:IM-28441-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000225698(gene)|ensembl:ENSG00000278042(gene)|ensembl:ENST00000433072(transcript)|ensembl:ENST00000633602(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|go:"GO:0042571"(immunoglobulin complex, circulating) - chain-seq-start:6433|chain-seq-end:6775 - figure legend:Table 2, no 10|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:f9/fchviwfMOLsD+x0i7iUJJe2c1263720 rogid:XsYPfPnXtVlLEAiM91+kQbYfx6k9606 rigid:Bjb8cavvsMjZXBfDIB9O9Jqg/PI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q96IV0 intact:EBI-25594444 intact:EBI-6165879|ensembl:ENSP00000280700|uniprotkb:B4DJE9|uniprotkb:Q59FB1|uniprotkb:Q6PJD8|uniprotkb:Q9BVR8|uniprotkb:Q9NR70 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ngly1_human(display_long)|uniprotkb:NGLY1(gene name)|psi-mi:NGLY1(display_short)|uniprotkb:N-glycanase 1(gene name synonym)|uniprotkb:PNG1(gene name synonym)|uniprotkb:"Peptide:N-glycanase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000151092(gene)|ensembl:ENST00000280700(transcript)|go:"GO:0000224"("peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR006588(Protein of unknown function PAW)|interpro:IPR008979(Galactose-binding like)|interpro:IPR018997|interpro:IPR036339|interpro:IPR038680|interpro:IPR038765|mint:Q96IV0|rcsb pdb:2CCQ|rcsb pdb:2CM0|reactome:R-HSA-532668|refseq:NP_001138767.1|refseq:NP_060767.2|refseq:NP_001138765.1|refseq:NP_001138766.1 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:CujOKLkvqxGmWpFvJM3B894PHqc9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q9UBV2 intact:EBI-25594444 intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q9Y305 intact:EBI-25594444 intact:EBI-2548214|ensembl:ENSP00000336580|uniprotkb:B3KNC9|uniprotkb:B7ZM94 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:acot9_human(display_long)|uniprotkb:ACOT9(gene name)|psi-mi:ACOT9(display_short)|uniprotkb:Acyl-CoA thioester hydrolase 9(gene name synonym)|uniprotkb:CGI-16(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000123130(gene)|ensembl:ENST00000336430(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR029069|interpro:IPR033120|mint:Q9Y305|reactome:R-HSA-77289|refseq:NP_001028755.2|refseq:NP_001032248.1|refseq:NP_001317188.1 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:WbPOPMGV/9XQRxLufTKCXvYQH/Y9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q9ULA0 intact:EBI-25594444 intact:EBI-748356|uniprotkb:Q9BW44|uniprotkb:Q9NUV5|uniprotkb:Q9NV55|ensembl:ENSP00000273075 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dnpep_human(display_long)|uniprotkb:ASPEP(gene name synonym)|uniprotkb:DAP(gene name synonym)|uniprotkb:DNPEP(gene name)|psi-mi:DNPEP(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001306049.1|refseq:NP_036232.2|ensembl:ENSG00000123992(gene)|ensembl:ENST00000273075(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0072562"(blood microparticle)|interpro:IPR001948(Peptidase M18, aminopeptidase I)|interpro:IPR023358|rcsb pdb:4DYO - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:xG06vZosglPmA5ktZd8A8EH9h0g9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q9P209 intact:EBI-25594444 intact:EBI-739498|uniprotkb:Q9BV03|uniprotkb:Q9BWM3|uniprotkb:Q9NVR4|uniprotkb:B4DR26|ensembl:ENSP00000264935 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cep72_human(display_long)|uniprotkb:CEP72(gene name)|psi-mi:CEP72(display_short)|uniprotkb:KIAA1519(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_060610.2|ensembl:ENSG00000112877(gene)|ensembl:ENST00000264935(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0033566"(gamma-tubulin complex localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:1904779"(regulation of protein localization to centrosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR040146|mint:Q9P209|reactome:R-HSA-2565942|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|refseq:XP_011512365.1|dip:DIP-54272N - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:c00WdgE2iudiQUz3kXNZL5d0nuQ9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q96RU2 intact:EBI-25594444 intact:EBI-2512342|ensembl:ENSP00000003302|uniprotkb:B0YJC0|uniprotkb:B0YJC1|uniprotkb:Q9P213|intact:EBI-2796288|uniprotkb:Q6NZX9 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubp28_human(display_long)|uniprotkb:USP28(gene name)|psi-mi:USP28(display_short)|uniprotkb:KIAA1515(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 28(gene name synonym)|uniprotkb:Deubiquitinating enzyme 28(gene name synonym)|uniprotkb:Ubiquitin thioesterase 28(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000048028(gene)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009060(UBA-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:Q96RU2|rcsb pdb:2LVA|rcsb pdb:2MUU|rcsb pdb:6H4H|rcsb pdb:6H4I|rcsb pdb:6HEH|rcsb pdb:6HEI|rcsb pdb:6HEJ|rcsb pdb:6HEK|reactome:R-HSA-5689880|ensembl:ENST00000003302(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_065937.1|refseq:NP_001333187.1|refseq:NP_001333202.1 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:axlPKHiS0KlPbl2dNx2h12/LtY09606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q96DZ1 intact:EBI-25594444 intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q92995 intact:EBI-25594444 intact:EBI-714351|uniprotkb:D3DNS2|uniprotkb:Q96B25|intact:EBI-28978985|ensembl:ENSP00000263966|uniprotkb:A8K2S3|uniprotkb:B4DYF3 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubp13_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 13(gene name synonym)|uniprotkb:Deubiquitinating enzyme 13(gene name synonym)|uniprotkb:Isopeptidase T-3(gene name synonym)|uniprotkb:USP13(gene name)|psi-mi:USP13(display_short)|uniprotkb:ISOT3(gene name synonym)|uniprotkb:Ubiquitin thioesterase 13(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_003931.2|ensembl:ENSG00000058056(gene)|ensembl:ENST00000263966(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044313"(protein K6-linked deubiquitination)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR009060(UBA-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016652(Ubiquitinyl hydrolase)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|interpro:IPR041432|rcsb pdb:2L80|rcsb pdb:2LBC|reactome:R-HSA-5689880|reactome:R-HSA-8948751|ensembl:ENSP00000263966|ensembl:ENST00000496897|ensembl:ENSP00000417146|dip:DIP-53511N - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:q6g2QmSYm3Xjoo+tv20s6cN8iHk9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q8IWR1 intact:EBI-25594444 intact:EBI-10262539|uniprotkb:A8K5G9|uniprotkb:D3DNL9|intact:EBI-28978637|ensembl:ENSP00000311219 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tri59_human(display_long)|uniprotkb:TRIM59(gene name)|psi-mi:TRIM59(display_short)|uniprotkb:RING finger protein 104(gene name synonym)|uniprotkb:RNF104(gene name synonym)|uniprotkb:TRIM57(gene name synonym)|uniprotkb:TSBF1(gene name synonym)|uniprotkb:Tumor suppressor TSBF-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSP00000311219|refseq:NP_775107.1|ensembl:ENSG00000213186(gene)|ensembl:ENST00000309784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:H9mqvlmF70Qy0U+4e6WWQ49l9MI9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q6PJI9 intact:EBI-25594444 intact:EBI-2515073|intact:EBI-28967178|ensembl:ENSP00000262144|uniprotkb:Q9HA43|uniprotkb:Q96PW5|uniprotkb:B3KRC3|uniprotkb:Q9BSW6|uniprotkb:Q71RE7 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wdr59_human(display_long)|uniprotkb:WDR59(gene name)|psi-mi:WDR59(display_short)|uniprotkb:KIAA1923(gene name synonym)|uniprotkb:WD repeat-containing protein 59(gene name synonym)|uniprotkb:FP977(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSP00000262144|ensembl:ENST00000616369|ensembl:ENSP00000482446|ensembl:ENSG00000103091(gene)|ensembl:ENST00000262144(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0061700"(GATOR2 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR006575(RWD)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039456|reactome:R-HSA-9639288|mint:Q6PJI9|refseq:NP_001311100.1|refseq:NP_085058.3 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:7yMOhbv8kjVuL8I+Zs+8fLF933k9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q15796 intact:EBI-25594444 intact:EBI-1040141|ensembl:ENSP00000262160|ensembl:ENSP00000384449 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:smad2_human(display_long)|uniprotkb:SMAD2(gene name)|psi-mi:SMAD2(display_short)|uniprotkb:MADH2(gene name synonym)|uniprotkb:MADR2(gene name synonym)|uniprotkb:Mad-related protein 2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)|uniprotkb:JV18-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001003652.1|refseq:NP_005892.1|refseq:XP_006722514.1|ensembl:ENSG00000175387(gene)|ensembl:ENST00000262160(transcript)|ensembl:ENST00000402690(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001706"(endoderm formation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009749"(response to glucose)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019902"(phosphatase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031016"(pancreas development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032444"(activin responsive factor complex)|go:"GO:0032924"(activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035265"(organ growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051098"(regulation of binding)|go:"GO:0060039"(pericardium development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062009"(secondary palate development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900224"(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15796|rcsb pdb:1DEV|rcsb pdb:1KHX|rcsb pdb:1U7V|rcsb pdb:2LB3|rcsb pdb:5XOD|rcsb pdb:5ZOJ|rcsb pdb:6M64|rcsb pdb:6ZVQ|rcsb pdb:7CO1|reactome:R-HSA-1181150|reactome:R-HSA-1502540|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-3304356|reactome:R-HSA-3311021|reactome:R-HSA-3315487|reactome:R-HSA-3656532|reactome:R-HSA-452723|reactome:R-HSA-5689880|reactome:R-HSA-9615017|reactome:R-HSA-9617828|refseq:XP_016881234.1|refseq:XP_016881235.1|refseq:XP_005258316.1|dip:DIP-29716N - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:B+vgtzdbCnUXt22sbXtPwuudTNs9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:Q13438 intact:EBI-25594444 intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:P54802 intact:EBI-25594444 intact:EBI-4402668|ensembl:ENSP00000225927 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:anag_human(display_long)|uniprotkb:NAGLU(gene name)|psi-mi:NAGLU(display_short)|uniprotkb:UFHSD1(gene name synonym)|uniprotkb:N-acetyl-alpha-glucosaminidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000108784(gene)|ensembl:ENST00000225927(transcript)|go:"GO:0004561"(alpha-N-acetylglucosaminidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0006027"(glycosaminoglycan catabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007781(Alpha-N-acetylglucosaminidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:NP_000254.2|interpro:IPR024240|interpro:IPR024732|interpro:IPR024733|interpro:IPR029018|rcsb pdb:4XWH|reactome:R-HSA-2024096|reactome:R-HSA-2206282 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:ntho16w2Zcr+3KhW8FgKWemVngE9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:P51659 intact:EBI-25594444 intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:P43686 intact:EBI-25594444 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:P11717 intact:EBI-25594444 intact:EBI-1048580|uniprotkb:Q7Z7G9|uniprotkb:Q96PT5|ensembl:ENSP00000349437 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mpri_human(display_long)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)|uniprotkb:IGF2R(gene name)|psi-mi:IGF2R(display_short)|uniprotkb:MPRI(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_000867.2|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|ensembl:ENSG00000197081(gene)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000356956(transcript)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0001889"(liver development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:P11717|rcsb pdb:1E6F|rcsb pdb:1GP0|rcsb pdb:1GP3|rcsb pdb:1GQB|rcsb pdb:1JPL|rcsb pdb:1JWG|rcsb pdb:1LF8|rcsb pdb:2CNJ|rcsb pdb:2L29|rcsb pdb:2L2A|rcsb pdb:2M68|rcsb pdb:2M6T|rcsb pdb:2V5N|rcsb pdb:2V5O|rcsb pdb:2V5P|rcsb pdb:5IEI|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6P8I|rcsb pdb:6V02|rcsb pdb:6Z30|rcsb pdb:6Z31|rcsb pdb:6Z32|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-6027N - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:7lkG6WR8MQ/SONiTV/8g1ZTtKTU9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:O95835 intact:EBI-25594444 intact:EBI-444209|uniprotkb:Q6PKD0|ensembl:ENSP00000253339|ensembl:ENSP00000437550 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lats1_human(display_long)|uniprotkb:Large tumor suppressor homolog 1(gene name synonym)|uniprotkb:WARTS protein kinase(gene name synonym)|uniprotkb:LATS1(gene name)|psi-mi:LATS1(display_short)|uniprotkb:WARTS(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_004681.1|ensembl:ENSP00000253339|ensembl:ENST00000392273|ensembl:ENSP00000444678|ensembl:ENSP00000437550|refseq:NP_001257448.1|dip:DIP-31516N|ensembl:ENSG00000131023(gene)|ensembl:ENST00000253339(transcript)|ensembl:ENST00000543571(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000819"(sister chromatid segregation)|go:"GO:0000922"(spindle pole)|go:"GO:0001827"(inner cell mass cell fate commitment)|go:"GO:0001828"(inner cell mass cellular morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030496"(midbody)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009060(UBA-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028741|interpro:IPR042706|rcsb pdb:4ZRK|rcsb pdb:5B5W|rcsb pdb:5BRK|reactome:R-HSA-2028269 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:9HqrE1bBG99E3O2d2ezyRtg2Bd49606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422453 uniprotkb:A3KMH1 intact:EBI-25594444 intact:EBI-308657|uniprotkb:Q5JTP6|uniprotkb:Q5VW08|uniprotkb:Q7Z6I9|uniprotkb:Q86YC9|uniprotkb:Q8N3E4|uniprotkb:O60310|ensembl:ENSP00000368612 psi-mi:k9n7c7-pro_0000422453(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vwa8_human(display_long)|uniprotkb:VWA8(gene name)|psi-mi:VWA8(display_short)|uniprotkb:KIAA0564(gene name synonym)|uniprotkb:PEX7-binding protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374786|imex:IM-28441-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000102763(gene)|ensembl:ENST00000379310(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|refseq:NP_001009814.1|refseq:NP_055873.1|refseq:XP_016875963.1 - chain-seq-start:6776|chain-seq-end:7078 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:A9N4KgaGtRF+hsZly70mm2Azk781263720 rogid:IOalBj68cHFF4BsViQ+eeXQZiRY9606 rigid:kmibeGhHRSIL1EF/LwIt72cS/cY false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q8TF46 intact:EBI-26374839 intact:EBI-3672244|uniprotkb:Q8N1N8|uniprotkb:Q8WTU9|uniprotkb:Q96CM7|ensembl:ENSP00000321711 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:di3l1_human(display_long)|uniprotkb:DIS3L1(gene name synonym)|uniprotkb:DIS3L(gene name)|psi-mi:DIS3L(display_short)|uniprotkb:KIAA1955(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001137160.1|refseq:NP_588616.1|refseq:NP_001310865.1|refseq:NP_001310867.1|refseq:NP_001310868.1|refseq:NP_001310870.1|refseq:NP_001310874.1|refseq:NP_001310875.1|ensembl:ENSG00000166938(gene)|ensembl:ENST00000319212(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019899"(enzyme binding)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR031192|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q8TF46 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:rxO2GoLqsuS4+/zLJsqCU8LFQyw9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q8WVC6 intact:EBI-26374839 intact:EBI-11319548|uniprotkb:Q9H5W1|uniprotkb:D3DX62|uniprotkb:D3DX60|uniprotkb:A8K3Z0|uniprotkb:Q9BR71|ensembl:ENSP00000308515|ensembl:ENSP00000341504|ensembl:ENSP00000413483|ensembl:ENSP00000467913|ensembl:ENSP00000478909|ensembl:ENSP00000498268 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:dcakd_human(display_long)|uniprotkb:DCAKD(gene name)|psi-mi:DCAKD(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:XP_016880591.1|refseq:XP_016880592.1|refseq:XP_016880593.1|refseq:NP_001122103.1|refseq:NP_001275583.1|refseq:NP_001275584.1|refseq:NP_079095.3|refseq:XP_005257745.1|refseq:XP_011523564.1|refseq:NP_001308255.1|ensembl:ENST00000651974(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016020"(membrane)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR027417|mint:Q8WVC6|ensembl:ENSG00000172992(gene)|ensembl:ENST00000310604(transcript)|ensembl:ENST00000342350(transcript)|ensembl:ENST00000452796(transcript)|ensembl:ENST00000588499(transcript)|ensembl:ENST00000614054(transcript) - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:b6jKOSLEjdHLqm69BmVHjW8R5G49606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q7L2H7 intact:EBI-26374839 intact:EBI-353901|intact:EBI-4289539|intact:EBI-715219|uniprotkb:Q2F836|uniprotkb:Q53HL6|uniprotkb:Q9BXW1|uniprotkb:O60735|uniprotkb:A8K7X4|intact:EBI-2559366|ensembl:ENSP00000436049|intact:EBI-373200|uniprotkb:B4E2Q4 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:eif3m_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)|uniprotkb:HFLB5(gene name synonym)|uniprotkb:PCID1(gene name synonym)|uniprotkb:PCI domain-containing protein 1(gene name synonym)|uniprotkb:Fetal lung protein B5(gene name synonym)|uniprotkb:GA17(orf name)|uniprotkb:PNAS-125(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_006351.2|refseq:NP_001294858.1|ensembl:ENSG00000149100(gene)|ensembl:ENST00000531120(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|mint:Q7L2H7|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31256N - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:siTfTDezqWL90pw6xG3xUKfY9n49606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q9UPQ9 intact:EBI-26374839 intact:EBI-947158|uniprotkb:B0QY78|uniprotkb:Q5TH52|uniprotkb:Q8TBX2|uniprotkb:B4DGC0|uniprotkb:B0QY73|ensembl:ENSP00000401946 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tnr6b_human(display_long)|uniprotkb:TNRC6B(gene name)|psi-mi:TNRC6B(display_short)|uniprotkb:KIAA1093(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001020014.1|refseq:NP_001155973.1|refseq:NP_055903.2|dip:DIP-29624N|ensembl:ENSG00000100354(gene)|ensembl:ENST00000454349(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR032226|interpro:IPR033500|interpro:IPR034925|interpro:IPR035979|mint:Q9UPQ9|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:A4yGG9Gt++0QN+6jFzfhWVYN+Dw9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q9UH62 intact:EBI-26374839 intact:EBI-717832|uniprotkb:Q53HC6|uniprotkb:Q7LCF5|uniprotkb:Q9NPE4|ensembl:ENSP00000340672|ensembl:ENSP00000439032|ensembl:ENSP00000454483 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:armx3_human(display_long)|uniprotkb:ARM protein lost in epithelial cancers on chromosome X 3(gene name synonym)|uniprotkb:ARMCX3(gene name)|psi-mi:ARMCX3(display_short)|uniprotkb:ALEX3(gene name synonym)|uniprotkb:BM-017(orf name)|uniprotkb:UNQ2517/PRO6007(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_057691.1|refseq:NP_808816.1|refseq:NP_808817.1|refseq:XP_005262198.1|ensembl:ENSG00000102401(gene)|ensembl:ENST00000341189(transcript)|ensembl:ENST00000471229(transcript)|ensembl:ENST00000537169(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000225(Armadillo)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-9013404 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:Svmu819cxCJThLvYapRMLQpAszw9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q9HD20 intact:EBI-26374839 intact:EBI-3940599|uniprotkb:B3KTA7|uniprotkb:B3KPJ2|uniprotkb:Q9H6C6|ensembl:ENSP00000349877|uniprotkb:Q6NT90|uniprotkb:Q6ZMG7 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:at131_human(display_long)|uniprotkb:ATP13A1(gene name)|psi-mi:ATP13A1(display_short)|uniprotkb:ATP13A(gene name synonym)|uniprotkb:KIAA1825(gene name synonym)|uniprotkb:CGI-152(orf name)|uniprotkb:Endoplasmic reticulum P5A-ATPase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000105726(gene)|ensembl:ENST00000357324(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140569"(extraction of mislocalized protein from ER membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q9HD20|reactome:R-HSA-936837|go:"GO:0015410"(ABC-type manganese transporter activity)|refseq:NP_065143.2 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:p4PEgZhH5QhoHI+InDMbLvdIBP09606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q9H1I8 intact:EBI-26374839 intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q9BQ70 intact:EBI-26374839 intact:EBI-745182|uniprotkb:Q2MK75|uniprotkb:Q9UPV3|ensembl:ENSP00000263346|ensembl:ENSP00000491638 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tcf25_human(display_long)|uniprotkb:Nuclear localized protein 1(gene name synonym)|uniprotkb:TCF25(gene name)|psi-mi:TCF25(display_short)|uniprotkb:KIAA1049(gene name synonym)|uniprotkb:NULP1(gene name synonym)|uniprotkb:FKSG26(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_055787.1|ensembl:ENSG00000141002(gene)|ensembl:ENST00000263346(transcript)|ensembl:ENST00000640279(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:1990112"(RQC complex)|interpro:IPR006994(Basic helix-loop-helix, Nulp1-type)|interpro:IPR011990(Tetratricopeptide-like helical) - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:+UEKIIV2LaFWrqJiOWgGU74ITVM9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q99613 intact:EBI-26374839 intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q96D09 intact:EBI-26374839 intact:EBI-473189|ensembl:ENSP00000339057|ensembl:ENSP00000437394|ensembl:ENSP00000437872|ensembl:ENSP00000507692|ensembl:ENSP00000508139|uniprotkb:Q8NAB4|uniprotkb:D3DXA0 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:gasp2_human(display_long)|uniprotkb:GPRASP2(gene name)|psi-mi:GPRASP2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000158301(gene)|ensembl:ENST00000332262(transcript)|ensembl:ENST00000483720(transcript)|ensembl:ENST00000486814(transcript)|ensembl:ENST00000535209(transcript)|ensembl:ENST00000543253(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043374|refseq:NP_001004051.1|refseq:NP_001171803.1|refseq:NP_001171804.1|refseq:NP_001171805.1|refseq:NP_001186747.1|refseq:NP_612446.1 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:aUbvpCvGto1y4Rqnri7qaKaygQ89606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q96B26 intact:EBI-26374839 intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:y/cReHiPMubzNruyETohBjbRick9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q96A26 intact:EBI-26374839 intact:EBI-6123466|uniprotkb:Q9NRN6|uniprotkb:Q9UJX8|ensembl:ENSP00000419088 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:f162a_human(display_long)|uniprotkb:FAM162A(gene name)|psi-mi:FAM162A(display_short)|uniprotkb:C3orf28(gene name synonym)|uniprotkb:E2IG5(gene name synonym)|uniprotkb:E2-induced gene 5 protein(gene name synonym)|uniprotkb:Growth and transformation-dependent protein(gene name synonym)|uniprotkb:DC16(orf name)|uniprotkb:FWP001(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_055182.3|ensembl:ENSG00000114023(gene)|ensembl:ENST00000477892(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR009432(Protein of unknown function DUF1075)|mint:Q96A26 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:CjOkqa9wFwEOorjQt5oI7/EJ6709606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q8NBU5 intact:EBI-26374839 intact:EBI-2511886|ensembl:ENSP00000339016|ensembl:ENSP00000339017|ensembl:ENSP00000489353|ensembl:ENSP00000489455|ensembl:ENSP00000506333|uniprotkb:Q6P4B9|uniprotkb:Q969Y3|uniprotkb:Q8WYR9|uniprotkb:Q8N3G1|uniprotkb:Q6DKG1|uniprotkb:D3DR26 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:atad1_human(display_long)|uniprotkb:ATAD1(gene name)|psi-mi:ATAD1(display_short)|uniprotkb:Thorase(gene name synonym)|uniprotkb:FNP001(orf name)|uniprotkb:ATPase family AAA domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000138138(gene)|ensembl:ENSG00000283024(gene)|ensembl:ENST00000308448(transcript)|ensembl:ENST00000328142(transcript)|ensembl:ENST00000634773(transcript)|ensembl:ENST00000634970(transcript)|ensembl:ENST00000680024(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|reactome:R-HSA-9603798|refseq:NP_116199.2|refseq:NP_001308896.1|refseq:XP_005270309.1|refseq:XP_016872336.1 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:IGkIH4udjuFoshP9hMDDK0ARNOg9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q8N9N2 intact:EBI-26374839 intact:EBI-10268317|uniprotkb:Q9Y307|uniprotkb:Q5SW06|uniprotkb:Q5SW07|uniprotkb:Q96EI8|ensembl:ENSP00000339404|ensembl:ENSP00000378373 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ascc1_human(display_long)|uniprotkb:ASCC1(gene name)|psi-mi:ASCC1(display_short)|uniprotkb:ASC-1 complex subunit p50(gene name synonym)|uniprotkb:Trip4 complex subunit p50(gene name synonym)|uniprotkb:CGI-18(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001185727.1|refseq:NP_001185728.1|refseq:NP_001185729.1|ensembl:ENSG00000138303(gene)|ensembl:ENST00000342444(transcript)|ensembl:ENST00000394915(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR004088(K Homology, type 1)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR009210(Predicted eukaryotic LigT)|interpro:IPR019510|interpro:IPR036612|reactome:R-HSA-112126|refseq:XP_006717936.1 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:WfbfIpzdDj8dd1Ez1PbcIy2tnSA9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q8N3C0 intact:EBI-26374839 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q6Y7W6 intact:EBI-26374839 intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q6NUN9 intact:EBI-26374839 intact:EBI-3862525|uniprotkb:A8K6Z9|uniprotkb:Q6ZRF9|ensembl:ENSP00000345140 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:zn746_human(display_long)|uniprotkb:PARIS(gene name synonym)|uniprotkb:ZNF746(gene name)|psi-mi:ZNF746(display_short)|uniprotkb:Parkin-interacting substrate(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001156946.1|refseq:NP_689770.3|ensembl:ENSG00000181220(gene)|ensembl:ENST00000340622(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:MlT4SO+v9Ahg4HY5x1b2QFCCGgc9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q5VT66 intact:EBI-26374839 intact:EBI-11903927|uniprotkb:A8K447|uniprotkb:B2D078|uniprotkb:Q5VVS9|uniprotkb:Q5VVT0|uniprotkb:Q5VVT1|uniprotkb:Q8N9P5|uniprotkb:Q96FN8|uniprotkb:Q9H6C7|ensembl:ENSP00000355877 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:marc1_human(display_long)|uniprotkb:MTARC1(gene name)|psi-mi:MTARC1(display_short)|uniprotkb:MARC1(gene name synonym)|uniprotkb:MOSC1(gene name synonym)|uniprotkb:Molybdenum cofactor sulfurase C-terminal domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_073583.3|refseq:XP_011508202.1|refseq:XP_011508206.1|ensembl:ENSG00000186205(gene)|ensembl:ENST00000366910(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016661"(oxidoreductase activity, acting on other nitrogenous compounds as donors)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0051410"(detoxification of nitrogen compound)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|go:"GO:0098809"(nitrite reductase activity)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|rcsb pdb:6FW2|reactome:R-HSA-211945 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:MVnfGK30icFS28a9p6qf739MKYs9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q5SZL2 intact:EBI-26374839 intact:EBI-2514702|ensembl:ENSP00000357477|uniprotkb:Q2TAM2|uniprotkb:Q9H289|uniprotkb:A1A4E1|uniprotkb:A2IDE5|uniprotkb:Q5T323|uniprotkb:Q7Z5K7|uniprotkb:A2A3P2|uniprotkb:F8W6J2|uniprotkb:G3V0H3 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ce85l_human(display_long)|uniprotkb:CEP85L(gene name)|psi-mi:CEP85L(display_short)|uniprotkb:C6orf204(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-15(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000111860(gene)|ensembl:ENST00000368491(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|interpro:IPR029778|interpro:IPR040210|refseq:XP_011534111.1|refseq:NP_001035940.1|refseq:NP_001171506.1|refseq:NP_996804.2|refseq:XP_016866335.1 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:N15ebFbq7U88FFmEjre+dOJsgeA9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q15650 intact:EBI-26374839 intact:EBI-2800143|uniprotkb:Q96ED7|uniprotkb:Q9UKH0|uniprotkb:B2RAS0|ensembl:ENSP00000261884 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:trip4_human(display_long)|uniprotkb:Thyroid receptor-interacting protein 4(gene name synonym)|uniprotkb:TRIP4(gene name)|psi-mi:TRIP4(display_short)|uniprotkb:RQT4(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_057297.2|refseq:NP_001308853.1|ensembl:ENSG00000103671(gene)|ensembl:ENST00000261884(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:1901998"(toxin transport)|interpro:IPR007374(Protein of unknown function DUF437)|interpro:IPR009349(Zinc finger, C2HC5-type)|interpro:IPR015947(PUA-like)|interpro:IPR039128|rcsb pdb:2E5O|go:"GO:0005815"(microtubule organizing center) - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:fecS9E0obnl+xsx/r9OrmToZEbs9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q13423 intact:EBI-26374839 intact:EBI-1391318|uniprotkb:Q16796|uniprotkb:Q2TB60|uniprotkb:Q8N3V4|ensembl:ENSP00000264663|ensembl:ENSP00000343873|ensembl:ENSP00000499249|ensembl:ENSP00000499281|ensembl:ENSP00000499494|ensembl:ENSP00000499527|ensembl:ENSP00000499611|ensembl:ENSP00000499639 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:nntm_human(display_long)|uniprotkb:NNT(gene name)|psi-mi:NNT(display_short)|uniprotkb:Nicotinamide nucleotide transhydrogenase(gene name synonym)|uniprotkb:Pyridine nucleotide transhydrogenase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_036475.3|refseq:NP_892022.2|refseq:XP_011512303.1|refseq:XP_016864782.1|refseq:XP_005248331.1|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903285"(positive regulation of hydrogen peroxide catabolic process)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR024605|interpro:IPR026255|interpro:IPR029035|interpro:IPR034300|interpro:IPR036291|mint:Q13423|rcsb pdb:1DJL|rcsb pdb:1PT9|rcsb pdb:1U31|reactome:R-HSA-71403|ensembl:ENSG00000112992(gene)|ensembl:ENST00000264663(transcript)|ensembl:ENST00000344920(transcript)|ensembl:ENST00000653251(transcript)|ensembl:ENST00000656666(transcript)|ensembl:ENST00000662525(transcript)|ensembl:ENST00000669601(transcript)|ensembl:ENST00000670904(transcript)|ensembl:ENST00000671668(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003957"("NAD(P)+ transhydrogenase (B-specific) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0008746"("NAD(P)+ transhydrogenase activity")|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0033273"(response to vitamin)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0072593"(reactive oxygen species metabolic process) - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:iDKBuEy/JvV9q3s4/aHuu58+Gyk9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:Q10471 intact:EBI-26374839 intact:EBI-10226985|uniprotkb:A8K1Y3|uniprotkb:C5HU00|uniprotkb:Q9NPY4|uniprotkb:B7Z8V8|ensembl:ENSP00000355632 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:galt2_human(display_long)|uniprotkb:GALNT2(gene name)|psi-mi:GALNT2(display_short)|uniprotkb:Polypeptide GalNAc transferase 2(gene name synonym)|uniprotkb:Protein-UDP acetylgalactosaminyltransferase 2(gene name synonym)|uniprotkb:"UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001278795.1|refseq:NP_004472.1|ensembl:ENSG00000143641(gene)|ensembl:ENST00000366672(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004653"(polypeptide N-acetylgalactosaminyltransferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0016020"(membrane)|go:"GO:0016266"(O-glycan processing)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0018243"(protein O-linked glycosylation via threonine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051604"(protein maturation)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035992|rcsb pdb:2FFU|rcsb pdb:2FFV|rcsb pdb:4D0T|rcsb pdb:4D0Z|rcsb pdb:4D11|rcsb pdb:5AJN|rcsb pdb:5AJO|rcsb pdb:5AJP|rcsb pdb:5FV9|rcsb pdb:5NDF|rcsb pdb:6E7I|rcsb pdb:6EGS|rcsb pdb:6NQT|reactome:R-HSA-6811436|reactome:R-HSA-913709 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:z7hqeQjq7k5iQZfnLHZ4ioplKPU9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:P16435 intact:EBI-26374839 intact:EBI-726554|uniprotkb:Q9UDT3|uniprotkb:Q16455|uniprotkb:Q8N181|uniprotkb:Q9H3M8|uniprotkb:Q197M5|ensembl:ENSP00000378355|ensembl:ENSP00000389409|ensembl:ENSP00000389719|ensembl:ENSP00000390540|ensembl:ENSP00000395813|ensembl:ENSP00000399327|ensembl:ENSP00000399556|ensembl:ENSP00000404731|ensembl:ENSP00000409238|ensembl:ENSP00000414263|ensembl:ENSP00000419970 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ncpr_human(display_long)|uniprotkb:POR(gene name)|psi-mi:POR(display_short)|uniprotkb:CYPOR(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_000932.3|ensembl:ENSG00000127948(gene)|ensembl:ENST00000394893(transcript)|ensembl:ENST00000412064(transcript)|ensembl:ENST00000412521(transcript)|ensembl:ENST00000414186(transcript)|ensembl:ENST00000418341(transcript)|ensembl:ENST00000432753(transcript)|ensembl:ENST00000439963(transcript)|ensembl:ENST00000449920(transcript)|ensembl:ENST00000453773(transcript)|ensembl:ENST00000454934(transcript)|ensembl:ENST00000461988(transcript)|go:"GO:0003420"(regulation of growth plate cartilage chondrocyte proliferation)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009725"(response to hormone)|go:"GO:0009812"(flavonoid metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0016787"(hydrolase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0022900"(electron transport chain)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032770"(positive regulation of monooxygenase activity)|go:"GO:0042493"|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043602"(nitrate catabolic process)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0047726"(iron-cytochrome-c reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0070988"(demethylation)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090031"(positive regulation of steroid hormone biosynthetic process)|go:"GO:0090346"(cellular organofluorine metabolic process)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR029039|interpro:IPR039261|rcsb pdb:1B1C|rcsb pdb:3FJO|rcsb pdb:3QE2|rcsb pdb:3QFC|rcsb pdb:3QFR|rcsb pdb:3QFS|rcsb pdb:3QFT|rcsb pdb:5EMN|rcsb pdb:5FA6|reactome:R-HSA-211897|dip:DIP-29682N - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:Tgl0hfwgwo16Yw+kH4JIdIaRPpM9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:P15954 intact:EBI-26374839 intact:EBI-2606678|uniprotkb:Q6NR81|ensembl:ENSP00000247655|ensembl:ENSP00000425759 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cox7c_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VIIc(gene name synonym)|uniprotkb:COX7C(gene name)|psi-mi:COX7C(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001858.1|ensembl:ENST00000247655(transcript)|ensembl:ENST00000509578(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004202(Cytochrome c oxidase subunit VIIc)|interpro:IPR036636|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000127184(gene) - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:hBYR7f5I8aE5H8JreIvHF8tg1HU9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:P00387 intact:EBI-26374839 intact:EBI-1046040|uniprotkb:O75675|uniprotkb:Q8TDL8|uniprotkb:Q8WTS8|uniprotkb:Q9UEN4|uniprotkb:Q9UEN5|uniprotkb:Q9UL55|uniprotkb:Q9UL56|uniprotkb:B1AHF2|uniprotkb:B7Z7L3|ensembl:ENSP00000338461 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:nb5r3_human(display_long)|uniprotkb:Diaphorase-1(gene name synonym)|uniprotkb:CYB5R3(gene name)|psi-mi:CYB5R3(display_short)|uniprotkb:DIA1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001165132.1|refseq:NP_000389.1|refseq:NP_001123291.1|refseq:NP_015565.1|refseq:NP_001165131.1|ensembl:ENSG00000100243(gene)|ensembl:ENST00000352397(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043531"(ADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|mint:P00387|rcsb pdb:1M91|rcsb pdb:1UMK|reactome:R-HSA-196836|reactome:R-HSA-211945|reactome:R-HSA-6798695|interpro:IPR039261|dip:DIP-50463N - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:Q8JTO6AXZ8LE4FXZAzOw2p4b6HY9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:O00746 intact:EBI-26374839 intact:EBI-744871|uniprotkb:Q5U0M9|ensembl:ENSP00000219479|uniprotkb:A2IDD0 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ndkm_human(display_long)|uniprotkb:nm23-H4(gene name synonym)|uniprotkb:Nucleoside diphosphate kinase D(gene name synonym)|uniprotkb:NME4(gene name)|psi-mi:NME4(display_short)|uniprotkb:NM23D(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001273362.1|refseq:NP_001273364.1|refseq:NP_001273365.1|refseq:NP_001273367.1|refseq:NP_001273368.1|refseq:NP_001273369.1|refseq:NP_005000.1|ensembl:ENSG00000103202(gene)|ensembl:ENST00000219479(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1901612"(cardiolipin binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:O00746|rcsb pdb:1EHW|reactome:R-HSA-499943 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:ybA9I8oT+oz1iuGLHT7WR1SAaKY9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422440 uniprotkb:O00186 intact:EBI-26374839 intact:EBI-2803005|uniprotkb:Q86YJ3|uniprotkb:A8K5K7|uniprotkb:Q9UPD7|uniprotkb:A8K269|intact:EBI-3255674|uniprotkb:Q53FW1|ensembl:ENSP00000359025 psi-mi:k9n7c7-pro_0000422440(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:stxb3_human(display_long)|uniprotkb:Platelet Sec1 protein(gene name synonym)|uniprotkb:Protein unc-18 homolog 3(gene name synonym)|uniprotkb:Protein unc-18 homolog C(gene name synonym)|uniprotkb:STXBP3(gene name)|psi-mi:STXBP3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374831|imex:IM-28441-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_009200.2|ensembl:ENSG00000116266(gene)|ensembl:ENST00000370008(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032868"(response to insulin)|go:"GO:0042581"(specific granule)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070820"(tertiary granule)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098793"(presynapse)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-HSA-114516|reactome:R-HSA-1445148 - chain-seq-start:194|chain-seq-end:853 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:eB7/AyO5x5TwetYCuZc/ihZ+W+81263720 rogid:iDBy0rQnIRdaV5yej86+OU1xcqk9606 rigid:tYMi/9xICdNvZ0HrDhgMWUcmyfU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422442 uniprotkb:Q92643 intact:EBI-25592244 intact:EBI-8617711|ensembl:ENSP00000359848|intact:MINT-2813159|uniprotkb:O14822|uniprotkb:B2R7K3|uniprotkb:Q5TG77|uniprotkb:B4E2M3 psi-mi:k9n7c7-pro_0000422442(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gpi8_human(display_long)|uniprotkb:PIGK(gene name)|psi-mi:PIGK(display_short)|uniprotkb:GPI8(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class K protein(gene name synonym)|uniprotkb:GPI8 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374899|imex:IM-28441-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000142892(gene)|ensembl:ENST00000370812(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003923"(GPI-anchor transamidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR028361|mint:Q92643|reactome:R-HSA-162791|refseq:NP_005473.1 - chain-seq-start:2741|chain-seq-end:3247 function:Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein|comment:mint figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:VI1f9u5Lj0UkB0nmHisqasUy62Q1263720 rogid:FRRsPTVrMU/nfpydL7D59VLlXxY9606 rigid:/jq6yQDoK5Q/mvcBM5x3/uCBBe0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422442 uniprotkb:Q96S52 intact:EBI-25592244 intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430 psi-mi:k9n7c7-pro_0000422442(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374899|imex:IM-28441-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1 - chain-seq-start:2741|chain-seq-end:3247 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:VI1f9u5Lj0UkB0nmHisqasUy62Q1263720 rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606 rigid:/jq6yQDoK5Q/mvcBM5x3/uCBBe0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422442 uniprotkb:Q969N2 intact:EBI-25592244 intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036 psi-mi:k9n7c7-pro_0000422442(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374899|imex:IM-28441-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2 - chain-seq-start:2741|chain-seq-end:3247 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:VI1f9u5Lj0UkB0nmHisqasUy62Q1263720 rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606 rigid:/jq6yQDoK5Q/mvcBM5x3/uCBBe0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422442 uniprotkb:Q8NFQ8 intact:EBI-25592244 intact:EBI-524567|ensembl:ENSP00000356584|ensembl:ENSP00000477486 psi-mi:k9n7c7-pro_0000422442(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:toip2_human(display_long)|uniprotkb:Lumenal domain-like LAP1(gene name synonym)|uniprotkb:TOR1AIP2(gene name)|psi-mi:TOR1AIP2(display_short)|uniprotkb:LULL1(gene name synonym)|uniprotkb:IFRG15(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374899|imex:IM-28441-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:XP_005244996.1|interpro:IPR008662(Lamina-associated polypeptide 1C)|ensembl:ENSG00000169905(gene)|ensembl:ENST00000367612(transcript)|ensembl:ENST00000609928(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|refseq:XP_016855963.1|refseq:XP_016855964.1|refseq:NP_001186189.1|refseq:NP_659471.1|interpro:IPR038599|rcsb pdb:5J1S|rcsb pdb:5J1T - chain-seq-start:2741|chain-seq-end:3247 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:VI1f9u5Lj0UkB0nmHisqasUy62Q1263720 rogid:HjY3sLjzR1jmKq2EqIKRvY3GxKc9606 rigid:/jq6yQDoK5Q/mvcBM5x3/uCBBe0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422442 uniprotkb:Q8NBJ7 intact:EBI-25592244 intact:EBI-723091|uniprotkb:Q14DW5|uniprotkb:Q53ZE3|uniprotkb:Q96BH2|uniprotkb:Q9BRN3|uniprotkb:Q9BWI1|uniprotkb:Q9Y405|ensembl:ENSP00000400922|uniprotkb:B4DU41|uniprotkb:B4DWQ0 psi-mi:k9n7c7-pro_0000422442(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sumf2_human(display_long)|uniprotkb:SUMF2(gene name)|psi-mi:SUMF2(display_short)|uniprotkb:Sulfatase-modifying factor 2(gene name synonym)|uniprotkb:PSEC0171(orf name)|uniprotkb:UNQ1968/PRO4500(orf name)|uniprotkb:Paralog of formylglycine-generating enzyme(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374899|imex:IM-28441-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001035934.2|refseq:NP_001035935.2|refseq:NP_001139805.1|refseq:NP_056226.2|refseq:NP_001123541.1|ensembl:ENSG00000129103(gene)|ensembl:ENST00000434526(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR005532(Sulphate-modifying factor-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR042095|rcsb pdb:1Y4J|reactome:R-HSA-1660662|reactome:R-HSA-1663150 - chain-seq-start:2741|chain-seq-end:3247 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:VI1f9u5Lj0UkB0nmHisqasUy62Q1263720 rogid:l5K3nL4Cf/sygAOzoS2fcH4rmL09606 rigid:/jq6yQDoK5Q/mvcBM5x3/uCBBe0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422442 uniprotkb:Q13586 intact:EBI-25592244 intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4 psi-mi:k9n7c7-pro_0000422442(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374899|imex:IM-28441-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N - chain-seq-start:2741|chain-seq-end:3247 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:VI1f9u5Lj0UkB0nmHisqasUy62Q1263720 rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606 rigid:/jq6yQDoK5Q/mvcBM5x3/uCBBe0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422442 uniprotkb:P49257 intact:EBI-25592244 intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047 psi-mi:k9n7c7-pro_0000422442(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374899|imex:IM-28441-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_005561.1|ensembl:ENSG00000074695(gene)|ensembl:ENST00000251047(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033085|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-948021|reactome:R-HSA-9013423|dip:DIP-42188N - chain-seq-start:2741|chain-seq-end:3247 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:VI1f9u5Lj0UkB0nmHisqasUy62Q1263720 rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606 rigid:/jq6yQDoK5Q/mvcBM5x3/uCBBe0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422442 uniprotkb:P13674 intact:EBI-25592244 intact:EBI-1237386|uniprotkb:Q15082|uniprotkb:Q15083|uniprotkb:Q5VSQ5|uniprotkb:C9JL12|ensembl:ENSP00000307318|ensembl:ENSP00000378353 psi-mi:k9n7c7-pro_0000422442(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p4ha1_human(display_long)|uniprotkb:P4HA1(gene name)|psi-mi:P4HA1(display_short)|uniprotkb:P4HA(gene name synonym)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374899|imex:IM-28441-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_000908.2|refseq:NP_001017962.1|refseq:NP_001136067.1|refseq:NP_001136068.1|dip:DIP-38180N|ensembl:ENSG00000122884(gene)|ensembl:ENST00000307116(transcript)|ensembl:ENST00000394890(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|interpro:IPR019734|mint:P13674|rcsb pdb:1TJC|rcsb pdb:2V5F|rcsb pdb:2YQ8|rcsb pdb:4BT8|rcsb pdb:4BT9|rcsb pdb:4BTA|rcsb pdb:4BTB|reactome:R-HSA-1650814|go:"GO:0043231"(intracellular membrane-bounded organelle) - chain-seq-start:2741|chain-seq-end:3247 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:VI1f9u5Lj0UkB0nmHisqasUy62Q1263720 rogid:Yo9hgWVJ5iUGITVWKfvjhTNX1lk9606 rigid:/jq6yQDoK5Q/mvcBM5x3/uCBBe0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q15032 intact:EBI-25592576 intact:EBI-2267290|uniprotkb:Q8IW32|uniprotkb:G5E9G8|uniprotkb:A8K1V0|uniprotkb:B3KXQ9|uniprotkb:E9PBB4|uniprotkb:E9PG42|ensembl:ENSP00000264160 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:r3hd1_human(display_long)|uniprotkb:R3HDM1(gene name)|psi-mi:R3HDM1(display_short)|uniprotkb:KIAA0029(gene name synonym)|uniprotkb:R3HDM(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001269727.1|refseq:NP_001269728.1|refseq:NP_001269729.1|refseq:XP_006712452.1|refseq:XP_016859207.1|refseq:NP_056176.2|ensembl:ENSP00000264160|ensembl:ENST00000409478|ensembl:ENSP00000386457|ensembl:ENST00000409606|ensembl:ENSP00000387010|ensembl:ENST00000410054|ensembl:ENSP00000386877|ensembl:ENST00000628915|ensembl:ENSP00000486837|ensembl:ENSG00000048991(gene)|ensembl:ENST00000264160(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR024771|interpro:IPR036867|mint:Q15032 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:TtKztiVREzd5YahM/O6ai/NLDE89606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q15118 intact:EBI-25592576 intact:EBI-7016221|uniprotkb:B7Z937|uniprotkb:E9PD65|uniprotkb:Q308M4|ensembl:ENSP00000282077|ensembl:ENSP00000386985|uniprotkb:B2R6T1|intact:MINT-2881420|uniprotkb:D3DPD8 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pdk1_human(display_long)|uniprotkb:PDK1(gene name)|psi-mi:PDK1(display_short)|uniprotkb:PDHK1(gene name synonym)|uniprotkb:Pyruvate dehydrogenase kinase isoform 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) dip:DIP-29497N|ensembl:ENSG00000152256(gene)|ensembl:ENST00000282077(transcript)|ensembl:ENST00000410055(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010510"(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:Q15118|rcsb pdb:2Q8F|rcsb pdb:2Q8G|rcsb pdb:2Q8H|reactome:R-HSA-204174|reactome:R-HSA-5362517|refseq:NP_002601.1|refseq:NP_001265478.1 - chain-seq-start:3248|chain-seq-end:3553 comment:mint|comment:homomint|function:Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:bGVYvRnjKgE4fa6X5wY5SveeIUM9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q9NYZ3 intact:EBI-25592576 intact:EBI-2511327|intact:EBI-28974182|ensembl:ENSP00000415430|uniprotkb:Q9BRE0|uniprotkb:Q53GX5|uniprotkb:Q20WK2|uniprotkb:Q9UGZ9|uniprotkb:Q6DHX4|uniprotkb:Q5R3I6|uniprotkb:Q9Y557|uniprotkb:B0QYM3 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gtse1_human(display_long)|uniprotkb:GTSE1(gene name)|psi-mi:GTSE1(display_short)|uniprotkb:Protein B99 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000075218(gene)|ensembl:ENST00000454366(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007017"(microtubule-based process)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|interpro:IPR026657|interpro:IPR026659|interpro:IPR032768|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-69481|reactome:R-HSA-8852276|ensembl:ENSP00000415430|refseq:NP_057510.4 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:3vSRRbx11yGNbuaniX7ZtqE/cLI9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q8NHV4 intact:EBI-25592576 intact:EBI-2555055|uniprotkb:B0AZN0|uniprotkb:Q8NA30|ensembl:ENSP00000266742|ensembl:ENSP00000404978|uniprotkb:G3V3F1|intact:EBI-11060992|uniprotkb:B4E145 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nedd1_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 1(gene name synonym)|uniprotkb:NEDD1(gene name)|psi-mi:NEDD1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001128647.1|refseq:NP_001128648.1|refseq:NP_690869.1|refseq:XP_011536205.1|ensembl:ENSG00000139350(gene)|ensembl:ENST00000266742(transcript)|ensembl:ENST00000429527(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|interpro:IPR036322|refseq:NP_001128649.1|refseq:XP_005268701.1|refseq:XP_006719300.1|dip:DIP-48838N - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:ljVRvS/VGrOlrJxqy3Z+8fAew0c9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q8NBN7 intact:EBI-25592576 intact:EBI-3922765|uniprotkb:Q96G88|uniprotkb:Q6UX79|ensembl:ENSP00000391121|ensembl:ENSP00000477512 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rdh13_human(display_long)|uniprotkb:RDH13(gene name)|psi-mi:RDH13(display_short)|uniprotkb:SDR7C3(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 7C member 3(gene name synonym)|uniprotkb:PSEC0082(orf name)|uniprotkb:UNQ736/PRO1430(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:XP_011524709.1|refseq:NP_001139443.1|refseq:NP_612421.1|ensembl:ENSG00000160439(gene)|ensembl:ENST00000615256(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0009644"(response to high light intensity)|go:"GO:0010842"(retina layer formation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q8NBN7|reactome:R-HSA-5365859|ensembl:ENSG00000276684(gene)|ensembl:ENST00000415061(transcript)|refseq:XP_005258530.1 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:UHfrKddjwiPXJ6xohB99Ua0jGZo9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q8IX12 intact:EBI-25592576 intact:EBI-356265|ensembl:ENSP00000265872|uniprotkb:A0JLT7|uniprotkb:A1L4P7|uniprotkb:A8K9D4|uniprotkb:B4DNP8|uniprotkb:B4DRK8|uniprotkb:Q5EBM3|uniprotkb:Q32NE3|uniprotkb:Q5VUP6|uniprotkb:Q6PIZ0|uniprotkb:Q6X935|uniprotkb:Q9H8N4|uniprotkb:Q9NVA7|uniprotkb:Q9NVQ0|uniprotkb:Q9NWM6 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ccar1_human(display_long)|uniprotkb:CCAR1(gene name)|psi-mi:CCAR1(display_short)|uniprotkb:CARP1(gene name synonym)|uniprotkb:DIS(gene name synonym)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Death inducer with SAP domain(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000060339(gene)|ensembl:ENST00000265872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8IX12|reactome:R-HSA-72163|refseq:NP_060707.2|refseq:NP_001269888.1|refseq:NP_001269889.1|dip:DIP-27607N - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:YnZve7StC4kAO8raUbp8T02jpe09606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q7KZI7 intact:EBI-25592576 intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|dip:DIP-31321N|ensembl:ENSG00000072518(gene)|ensembl:ENST00000402010(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001764"(neuron migration)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q6ZRY4 intact:EBI-25592576 intact:EBI-11987469|ensembl:ENSP00000300069|uniprotkb:A2RRG0 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rbps2_human(display_long)|uniprotkb:RNA binding protein, mRNA processing factor 2(gene name synonym)|uniprotkb:RBPMS2(gene name)|psi-mi:RBPMS2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000166831(gene)|ensembl:ENST00000300069(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034787|interpro:IPR035979|rcsb pdb:2M9K|refseq:NP_919248.1 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:izNVmsysd7xvCB7xBFYI6GX+GC49606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q14244 intact:EBI-25592576 intact:EBI-2211064|uniprotkb:Q7Z6S0|uniprotkb:Q8TAU5|uniprotkb:Q9NY82|uniprotkb:Q9NY83|uniprotkb:B7Z290|uniprotkb:B7Z9U7|uniprotkb:C9JPS0|uniprotkb:F5H1E2|uniprotkb:B7Z400|uniprotkb:B7Z5S7|uniprotkb:E9PCP3|ensembl:ENSP00000346581 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:map7_human(display_long)|uniprotkb:MAP7(gene name)|psi-mi:MAP7(display_short)|uniprotkb:Microtubule-associated protein 7(gene name synonym)|uniprotkb:Epithelial microtubule-associated protein of 115 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001185537.1|refseq:NP_001185543.1|refseq:XP_016866960.1|refseq:NP_001185544.1|refseq:NP_001185545.1|refseq:NP_001185546.1|refseq:NP_001185547.1|refseq:NP_003971.1|refseq:NP_001185538.1|refseq:NP_001185540.1|refseq:NP_001185548.1|refseq:XP_006715663.1|ensembl:ENSP00000346581|ensembl:ENST00000432797|ensembl:ENSP00000414879|ensembl:ENST00000438100|ensembl:ENSP00000400790|ensembl:ENST00000454590|ensembl:ENSP00000414712|ensembl:ENST00000544465|ensembl:ENSP00000445737|ensembl:ENST00000611373|ensembl:ENSP00000482998|ensembl:ENST00000616617|ensembl:ENSP00000483511|ensembl:ENST00000618822|ensembl:ENSP00000482356|ensembl:ENSG00000135525(gene)|ensembl:ENST00000354570(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR008604(E-MAP-115)|interpro:IPR030707|mint:Q14244 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:2BB4pZbXcipOIHXEqAUpq3mEuw49606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:Q12948 intact:EBI-25592576 intact:EBI-1175253|uniprotkb:Q86UP7|uniprotkb:Q9BYM1|uniprotkb:Q9NUE5|uniprotkb:Q9UDD0|uniprotkb:Q9UP06|ensembl:ENSP00000493906 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:foxc1_human(display_long)|uniprotkb:Forkhead-related protein FKHL7(gene name synonym)|uniprotkb:Forkhead-related transcription factor 3(gene name synonym)|uniprotkb:FOXC1(gene name)|psi-mi:FOXC1(display_short)|uniprotkb:FKHL7(gene name synonym)|uniprotkb:FREAC3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENST00000645831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001654"(eye development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|ensembl:ENSG00000054598(gene)|go:"GO:0001822"(kidney development)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0021549"(cerebellum development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0008301"(DNA binding, bending)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:0060038"(cardiac muscle cell proliferation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR033067|go:"GO:0070098"(chemokine-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|mint:Q12948|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072010"(glomerular epithelium development)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902038"(positive regulation of hematopoietic stem cell differentiation)|go:"GO:1902257"(negative regulation of apoptotic process involved in outflow tract morphogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|ensembl:ENSP00000493906|refseq:NP_001444.2 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:+HuKwX8xMx86iCQW/a+vy/rWP389606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:P52952 intact:EBI-25592576 intact:EBI-936601|uniprotkb:A8K3K0|uniprotkb:B4DNB6|uniprotkb:E9PBU6|ensembl:ENSP00000327758 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nkx25_human(display_long)|uniprotkb:NKX2-5(gene name)|psi-mi:NKX2-5(display_short)|uniprotkb:CSX(gene name synonym)|uniprotkb:NKX2.5(gene name synonym)|uniprotkb:NKX2E(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog E(gene name synonym)|uniprotkb:Cardiac-specific homeobox(gene name synonym)|uniprotkb:Homeobox protein CSX(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001159647.1|refseq:NP_001159648.1|refseq:NP_004378.1|ensembl:ENSG00000183072(gene)|ensembl:ENST00000329198(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001947"(heart looping)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003166"(bundle of His development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003221"(right ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003228"(atrial cardiac muscle tissue development)|go:"GO:0003285"(septum secundum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007512"(adult heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033629|rcsb pdb:3RKQ|rcsb pdb:4S0H|rcsb pdb:6WC2|rcsb pdb:6WC5|reactome:R-HSA-2032785|reactome:R-HSA-5578768 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:wLSYYxUoPmhRfcbEfCdGPPv4qCQ9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:P29558 intact:EBI-25592576 intact:EBI-5462600|uniprotkb:Q14869|uniprotkb:Q15433|uniprotkb:Q53P46|uniprotkb:Q53QX8|uniprotkb:Q53RG6|uniprotkb:Q8WV20|ensembl:ENSP00000294904 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rbms1_human(display_long)|uniprotkb:RBMS1(gene name)|psi-mi:RBMS1(display_short)|uniprotkb:C2orf12(gene name synonym)|uniprotkb:MSSP(gene name synonym)|uniprotkb:MSSP1(gene name synonym)|uniprotkb:SCR2(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein MSSP-1(gene name synonym)|uniprotkb:Suppressor of CDC2 with RNA-binding motif 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_002888.1|refseq:NP_058520.1|ensembl:ENSG00000153250(gene)|ensembl:ENST00000348849(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034404|interpro:IPR035979|rcsb pdb:1X5O|rcsb pdb:6M75|rcsb pdb:7C36 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:npZQ2ZTonN9Bh4WMnboyvZYCv3Q9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:P19447 intact:EBI-25592576 intact:EBI-1183307|uniprotkb:Q53QM0|ensembl:ENSP00000285398 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ercc3_human(display_long)|uniprotkb:ERCC3(gene name)|psi-mi:ERCC3(display_short)|uniprotkb:XPB(gene name synonym)|uniprotkb:XPBC(gene name synonym)|uniprotkb:Basic transcription factor 2 89 kDa subunit(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 89 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein complementing XP-B cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group B-complementing protein(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_000113.1|ensembl:ENSG00000163161(gene)|ensembl:ENST00000285398(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|mint:P19447|rcsb pdb:4ERN|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-73863|dip:DIP-83N - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:KOM9+f636LHK8qfTFkLIm0X0VoY9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:P15923 intact:EBI-25592576 intact:EBI-769630|uniprotkb:Q2TB40|uniprotkb:P15883|uniprotkb:Q14208|uniprotkb:Q14635|uniprotkb:Q14636|uniprotkb:Q9UPI9|uniprotkb:Q2TB39|intact:EBI-11119608|ensembl:ENSP00000262965 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tfe2_human(display_long)|uniprotkb:Immunoglobulin enhancer-binding factor E12/E47(gene name synonym)|uniprotkb:Transcription factor 3(gene name synonym)|uniprotkb:Immunoglobulin transcription factor 1(gene name synonym)|uniprotkb:Transcription factor ITF-1(gene name synonym)|uniprotkb:Kappa-E2-binding factor(gene name synonym)|uniprotkb:TCF3(gene name)|psi-mi:TCF3(display_short)|uniprotkb:E2A(gene name synonym)|uniprotkb:ITF1(gene name synonym)|uniprotkb:BHLHB21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 21(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001129611.1|refseq:NP_003191.1|refseq:XP_016882669.1|refseq:XP_016882670.1|refseq:XP_016882671.1|dip:DIP-74N|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000071564(gene)|ensembl:ENST00000262965(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0042803"(protein homodimerization activity)|rcsb pdb:2YPA|rcsb pdb:2YPB|rcsb pdb:3U5V|rcsb pdb:6MGN|reactome:R-HSA-525793|reactome:R-HSA-8939236|rcsb pdb:2MH0|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070644"(vitamin D response element binding)|go:"GO:0070888"(E-box binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1HLH - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:EybpTkEZM4cIWyf25UVHfaOaP3Y9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:P15170 intact:EBI-25592576 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:O75629 intact:EBI-25592576 intact:EBI-2841839|uniprotkb:Q8N9A3|uniprotkb:B2RDD4|ensembl:ENSP00000359540 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:creg1_human(display_long)|uniprotkb:CREG1(gene name)|psi-mi:CREG1(display_short)|uniprotkb:CREG(gene name synonym)|uniprotkb:Cellular repressor of E1A-stimulated genes 1(gene name synonym)|uniprotkb:UNQ727/PRO1409(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_003842.1|ensembl:ENSG00000143162(gene)|ensembl:ENST00000370509(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0040008"(regulation of growth)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012349(FMN-binding split barrel)|interpro:IPR014631("Cellular repressor of E1A-stimulated genes (CREG)")|mint:O75629|rcsb pdb:1XHN|reactome:R-HSA-6798695 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:zE4O7jC/op4AMgKPkPAfnoJsBHk9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422443 uniprotkb:O15014 intact:EBI-25592576 intact:EBI-948874|intact:EBI-28988504|ensembl:ENSP00000316527|uniprotkb:Q0D2I2 psi-mi:k9n7c7-pro_0000422443(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zn609_human(display_long)|uniprotkb:ZNF609(gene name)|psi-mi:ZNF609(display_short)|uniprotkb:KIAA0295(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374923|imex:IM-28441-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) dip:DIP-50012N|ensembl:ENSG00000180357(gene)|ensembl:ENST00000326648(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR040010|mint:O15014|refseq:NP_055857.1|refseq:XP_011519688.1|ensembl:ENSP00000316527|refseq:XP_016877510.1 - chain-seq-start:3248|chain-seq-end:3553 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:y7LRjUSjTxAlsiZYr/YWDysjvA81263720 rogid:lg9CqF10xeIzDGib19G9feQpBIY9606 rigid:iSLfZpXSopG7Is3WNQVdu2pi1C0 false strep tag:?-?|mutation:148-148 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422444 uniprotkb:Q9UDY4 intact:EBI-26374958 intact:EBI-356960|uniprotkb:Q13431|uniprotkb:B2R824|ensembl:ENSP00000359799 psi-mi:k9n7c7-pro_0000422444(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:dnjb4_human(display_long)|uniprotkb:DNAJB4(gene name)|psi-mi:DNAJB4(display_short)|uniprotkb:DNAJW(gene name synonym)|uniprotkb:HLJ1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1 homolog(gene name synonym)|uniprotkb:Human liver DnaJ-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374950|imex:IM-28441-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_008965.2|refseq:NP_001304028.1|refseq:NP_001304029.1|refseq:NP_001304030.1|refseq:NP_001304031.1|refseq:NP_001304032.1|ensembl:ENSG00000162616(gene)|ensembl:ENST00000370763(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009408"(response to heat)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UDY4 - chain-seq-start:3554|chain-seq-end:3845 - figure legend:Table 2, no 15|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:pAeDhmOrdaAO2iZkBd090X7nEyU1263720 rogid:gN0zBtJQiTN+YYSAtMk1mddNWLU9606 rigid:nJdPbo9YAfL4dAJuB3KPNZeBHRw false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422444 uniprotkb:P25685 intact:EBI-26374958 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:k9n7c7-pro_0000422444(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374950|imex:IM-28441-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding) - chain-seq-start:3554|chain-seq-end:3845 - figure legend:Table 2, no 15|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:pAeDhmOrdaAO2iZkBd090X7nEyU1263720 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 rigid:nJdPbo9YAfL4dAJuB3KPNZeBHRw false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q8WVC6 intact:EBI-25592074 intact:EBI-11319548|uniprotkb:Q9H5W1|uniprotkb:D3DX62|uniprotkb:D3DX60|uniprotkb:A8K3Z0|uniprotkb:Q9BR71|ensembl:ENSP00000308515|ensembl:ENSP00000341504|ensembl:ENSP00000413483|ensembl:ENSP00000467913|ensembl:ENSP00000478909|ensembl:ENSP00000498268 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dcakd_human(display_long)|uniprotkb:DCAKD(gene name)|psi-mi:DCAKD(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:XP_016880591.1|refseq:XP_016880592.1|refseq:XP_016880593.1|refseq:NP_001122103.1|refseq:NP_001275583.1|refseq:NP_001275584.1|refseq:NP_079095.3|refseq:XP_005257745.1|refseq:XP_011523564.1|refseq:NP_001308255.1|ensembl:ENST00000651974(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016020"(membrane)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR027417|mint:Q8WVC6|ensembl:ENSG00000172992(gene)|ensembl:ENST00000310604(transcript)|ensembl:ENST00000342350(transcript)|ensembl:ENST00000452796(transcript)|ensembl:ENST00000588499(transcript)|ensembl:ENST00000614054(transcript) - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:b6jKOSLEjdHLqm69BmVHjW8R5G49606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q9Y5J7 intact:EBI-25592074 intact:EBI-1200370|uniprotkb:B2R584|ensembl:ENSP00000378588|ensembl:ENSP00000450638|ensembl:ENSP00000451006|ensembl:ENSP00000451198 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tim9_human(display_long)|uniprotkb:TIMM9(gene name)|psi-mi:TIMM9(display_short)|uniprotkb:TIM9(gene name synonym)|uniprotkb:TIM9A(gene name synonym)|uniprotkb:TIMM9A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001291415.1|refseq:NP_001291414.1|refseq:NP_001291416.1|refseq:NP_001291417.1|refseq:NP_001291418.1|refseq:NP_001291419.1|refseq:NP_001291420.1|refseq:NP_036592.1|ensembl:ENSG00000100575(gene)|ensembl:ENST00000395159(transcript)|ensembl:ENST00000555061(transcript)|ensembl:ENST00000555404(transcript)|ensembl:ENST00000555593(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032977"(membrane insertase activity)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0051087"(chaperone binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|rcsb pdb:2BSK|rcsb pdb:7CGP|reactome:R-HSA-1268020|go:"GO:0008270"(zinc ion binding) - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:a/L4LPXEAEVYZ54duHzDlaBt9W49606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q9NX40 intact:EBI-25592074 intact:EBI-2683029|uniprotkb:C9K030|uniprotkb:Q9BZE8|ensembl:ENSP00000264312|ensembl:ENSP00000370882|ensembl:ENSP00000423002|ensembl:ENSP00000423909|uniprotkb:G8JLN7 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ocad1_human(display_long)|uniprotkb:OCIA(gene name synonym)|uniprotkb:Ovarian carcinoma immunoreactive antigen(gene name synonym)|uniprotkb:OCIAD1(gene name)|psi-mi:OCIAD1(display_short)|uniprotkb:ASRIJ(gene name synonym)|uniprotkb:Ovarian cancer immunoreactive antigen domain containing 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001073309.1|refseq:NP_001073311.2|refseq:NP_001073308.1|refseq:NP_001073310.1|refseq:NP_060300.1|ensembl:ENSG00000109180(gene)|ensembl:ENST00000264312(transcript)|ensembl:ENST00000381473(transcript)|ensembl:ENST00000508293(transcript)|ensembl:ENST00000513391(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187|mint:Q9NX40|refseq:XP_016863818.1 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:e3Ojv8LBlgj056bssUZjEC+MB+Q9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q9H7Z7 intact:EBI-25592074 intact:EBI-681645|uniprotkb:Q53EW9|uniprotkb:Q5SYV6|uniprotkb:Q96GI0|uniprotkb:Q96GL2|ensembl:ENSP00000345341 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pges2_human(display_long)|uniprotkb:Microsomal prostaglandin E synthase 2(gene name synonym)|uniprotkb:PTGES2(gene name)|psi-mi:PTGES2(display_short)|uniprotkb:PGES2(gene name synonym)|uniprotkb:C9orf15(gene name synonym)|uniprotkb:Membrane-associated prostaglandin E synthase-2(gene name synonym)|uniprotkb:"Prostaglandin-H(2) E-isomerase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001243264.1|refseq:NP_079348.1|refseq:NP_945176.1|ensembl:ENSG00000148334(gene)|ensembl:ENST00000338961(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016829"(lyase activity)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0020037"(heme binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036134"(12-hydroxyheptadecatrienoic acid synthase activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050220"(prostaglandin-E synthase activity)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034334|interpro:IPR034335|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:Q9H7Z7|reactome:R-HSA-2162123|reactome:R-HSA-6798695 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:DFALgQTHlFSBHZUZBKTJNxxSqjk9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q9BQE4 intact:EBI-25592074 intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process) - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q96A26 intact:EBI-25592074 intact:EBI-6123466|uniprotkb:Q9NRN6|uniprotkb:Q9UJX8|ensembl:ENSP00000419088 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:f162a_human(display_long)|uniprotkb:FAM162A(gene name)|psi-mi:FAM162A(display_short)|uniprotkb:C3orf28(gene name synonym)|uniprotkb:E2IG5(gene name synonym)|uniprotkb:E2-induced gene 5 protein(gene name synonym)|uniprotkb:Growth and transformation-dependent protein(gene name synonym)|uniprotkb:DC16(orf name)|uniprotkb:FWP001(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_055182.3|ensembl:ENSG00000114023(gene)|ensembl:ENST00000477892(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR009432(Protein of unknown function DUF1075)|mint:Q96A26 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:CjOkqa9wFwEOorjQt5oI7/EJ6709606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q8WUY8 intact:EBI-25592074 intact:EBI-3919010|ensembl:ENSP00000205194|uniprotkb:Q8TDY7|uniprotkb:Q9NS72 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nat14_human(display_long)|uniprotkb:NAT14(gene name)|psi-mi:NAT14(display_short)|uniprotkb:KLP1(gene name synonym)|uniprotkb:K562 cell-derived leucine-zipper-like protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000090971(gene)|ensembl:ENST00000205194(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:Q8WUY8|refseq:NP_065111.1 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:zAcaUhoopgHpFaxfNM6H4jd4d089606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q8NBU5 intact:EBI-25592074 intact:EBI-2511886|ensembl:ENSP00000339016|ensembl:ENSP00000339017|ensembl:ENSP00000489353|ensembl:ENSP00000489455|ensembl:ENSP00000506333|uniprotkb:Q6P4B9|uniprotkb:Q969Y3|uniprotkb:Q8WYR9|uniprotkb:Q8N3G1|uniprotkb:Q6DKG1|uniprotkb:D3DR26 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:atad1_human(display_long)|uniprotkb:ATAD1(gene name)|psi-mi:ATAD1(display_short)|uniprotkb:Thorase(gene name synonym)|uniprotkb:FNP001(orf name)|uniprotkb:ATPase family AAA domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000138138(gene)|ensembl:ENSG00000283024(gene)|ensembl:ENST00000308448(transcript)|ensembl:ENST00000328142(transcript)|ensembl:ENST00000634773(transcript)|ensembl:ENST00000634970(transcript)|ensembl:ENST00000680024(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140570"(extraction of mislocalized protein from mitochondrial outer membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|reactome:R-HSA-9603798|refseq:NP_116199.2|refseq:NP_001308896.1|refseq:XP_005270309.1|refseq:XP_016872336.1 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:IGkIH4udjuFoshP9hMDDK0ARNOg9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q8N9F7 intact:EBI-25592074 intact:EBI-6138712|uniprotkb:A8W735|uniprotkb:Q56VR1|uniprotkb:Q8N4E3|ensembl:ENSP00000284116 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gdpd1_human(display_long)|uniprotkb:Glycerophosphodiester phosphodiesterase domain-containing protein 1(gene name synonym)|uniprotkb:GDPD1(gene name)|psi-mi:GDPD1(display_short)|uniprotkb:GDE4(gene name synonym)|uniprotkb:Glycerophosphodiester phosphodiesterase 4(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001159465.1|refseq:NP_001159466.1|refseq:NP_872375.2|ensembl:ENSG00000153982(gene)|ensembl:ENST00000284116(transcript)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070291"(N-acylethanolamine metabolic process)|interpro:IPR017946|interpro:IPR030395|reactome:R-HSA-6814848 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:Zjj8/PujRu/XeaaV2M9fmycA8e09606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q8N2K0 intact:EBI-25592074 intact:EBI-6269657|uniprotkb:A6NED4|uniprotkb:A6NJ90|uniprotkb:A8K450|uniprotkb:B4DE71|uniprotkb:Q5T710|uniprotkb:Q5T711|uniprotkb:Q96CR1|uniprotkb:Q9BX05|uniprotkb:Q9NPX7|uniprotkb:Q9UFV6|ensembl:ENSP00000341408 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:abd12_human(display_long)|uniprotkb:ABHD12(gene name)|psi-mi:ABHD12(display_short)|uniprotkb:C20orf22(gene name synonym)|uniprotkb:Abhydrolase domain-containing protein 12(gene name synonym)|uniprotkb:2-arachidonoylglycerol hydrolase ABHD12(gene name synonym)|uniprotkb:Monoacylglycerol lipase ABHD12(gene name synonym)|uniprotkb:Oxidized phosphatidylserine lipase ABHD12(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001035937.1|refseq:NP_056415.1|ensembl:ENSP00000341408|ensembl:ENST00000376542|ensembl:ENSP00000365725|ensembl:ENSG00000100997(gene)|ensembl:ENST00000339157(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006660"(phosphatidylserine catabolic process)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0046464"(acylglycerol catabolic process)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0052651"(monoacylglycerol catabolic process)|interpro:IPR022742|interpro:IPR026605|interpro:IPR029058|mint:Q8N2K0|reactome:R-HSA-426048 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:l5KeOxi83Cng20JUGy7ybEtoCPg9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q6ZRP7 intact:EBI-25592074 intact:EBI-11127401|uniprotkb:Q7Z7B6|uniprotkb:Q8N3G2|uniprotkb:A6NLB0|uniprotkb:Q86VV7|uniprotkb:Q5TB37|uniprotkb:A2CEE0|ensembl:ENSP00000351536 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:qsox2_human(display_long)|uniprotkb:QSOX2(gene name)|psi-mi:QSOX2(display_short)|uniprotkb:Neuroblastoma-derived sulfhydryl oxidase(gene name synonym)|uniprotkb:QSCN6L1(gene name synonym)|uniprotkb:Quiescin Q6-like protein 1(gene name synonym)|uniprotkb:SOXN(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_859052.3|ensembl:ENSG00000165661(gene)|ensembl:ENST00000358701(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017905|interpro:IPR036249|interpro:IPR036774|interpro:IPR039798|interpro:IPR040986|interpro:IPR041269|interpro:IPR042568 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:P58P7yZCL+dIpUXwETr5Ppt/SQw9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q6P1Q0 intact:EBI-25592074 intact:EBI-1549822|uniprotkb:B3KXK7|uniprotkb:A6NER7|uniprotkb:Q6X2E4|uniprotkb:Q6X2E5|uniprotkb:Q7L2G9|uniprotkb:Q7L690|uniprotkb:Q8WXW6|uniprotkb:Q96PK7|uniprotkb:Q9Y3X3|uniprotkb:Q9BY59|intact:EBI-10972516|ensembl:ENSP00000262055 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ltmd1_human(display_long)|uniprotkb:LETMD1(gene name)|psi-mi:LETMD1(display_short)|uniprotkb:Cervical cancer 1 proto-oncogene protein p40(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 2 protein(gene name synonym)|uniprotkb:HCRR-2(gene name synonym)|uniprotkb:HCCR-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_056231.3|refseq:XP_006719402.1|refseq:XP_006719403.1|refseq:NP_001230618.1|ensembl:ENSG00000050426(gene)|ensembl:ENST00000262055(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043022"(ribosome binding)|interpro:IPR011685(LETM1-like)|interpro:IPR033122|interpro:IPR044202|mint:Q6P1Q0 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:iyp46kHqB7mu8W0BYCn64BDkVVU9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q6P1M0 intact:EBI-25592074 intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q53H12 intact:EBI-25592074 intact:EBI-2269837|uniprotkb:Q75KN1|uniprotkb:Q96GC3|uniprotkb:Q9NP48|ensembl:ENSP00000496789|ensembl:ENSP00000497280|ensembl:ENSP00000498112|ensembl:ENSP00000458417 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:agk_human(display_long)|uniprotkb:AGK(gene name)|psi-mi:AGK(display_short)|uniprotkb:MULK(gene name synonym)|uniprotkb:Multiple substrate lipid kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:XP_011514699.1|refseq:NP_060708.1|ensembl:ENSG00000006530(gene)|ensembl:ENST00000575872(transcript)|ensembl:ENST00000648068(transcript)|ensembl:ENST00000649286(transcript)|ensembl:ENST00000650547(transcript)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0001729"(ceramide kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042721"(TIM22 mitochondrial import inner membrane insertion complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046486"(glycerolipid metabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047620"(acylglycerol kinase activity)|go:"GO:0102773"(dihydroceramide kinase activity)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|go:"GO:0005743"(mitochondrial inner membrane)|ensembl:ENSG00000262327(gene)|rcsb pdb:7CGP|reactome:R-HSA-1483206|reactome:R-HSA-6802952|mint:Q53H12 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:aUz/aYnkviiUE/ijNEddfOQmjZQ9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:Q13724 intact:EBI-25592074 intact:EBI-720141|uniprotkb:Q17RN9|uniprotkb:Q8TCT5|uniprotkb:A8K938|ensembl:ENSP00000410992|uniprotkb:F5H6D0 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mogs_human(display_long)|uniprotkb:Processing A-glucosidase I(gene name synonym)|uniprotkb:MOGS(gene name)|psi-mi:MOGS(display_short)|uniprotkb:GCS1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001139630.1|refseq:NP_006293.2|ensembl:ENSG00000115275(gene)|ensembl:ENST00000448666(transcript)|go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0015926"(glucosidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|mint:Q13724|reactome:R-HSA-4793954|reactome:R-HSA-532668|reactome:R-HSA-9683686|reactome:R-HSA-9694548 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:odbL3NUcP483ilKg/CMVn2GtdVs9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:O95573 intact:EBI-25592074 intact:EBI-1190822|uniprotkb:Q60I92|uniprotkb:Q8IUM9|ensembl:ENSP00000350012|ensembl:ENSP00000375918|ensembl:ENSP00000504861|ensembl:ENSP00000504907|ensembl:ENSP00000505400|ensembl:ENSP00000505654|ensembl:ENSP00000505793|ensembl:ENSP00000505856|ensembl:ENSP00000505940|ensembl:ENSP00000506361|ensembl:ENSP00000506468|intact:EBI-21359981 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:acsl3_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:ACSL3(gene name)|psi-mi:ACSL3(display_short)|uniprotkb:ACS3(gene name synonym)|uniprotkb:FACL3(gene name synonym)|uniprotkb:LACS3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase 3(gene name synonym)|uniprotkb:Medium-chain acyl-CoA ligase Acsl3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_004448.2|refseq:NP_976251.1|refseq:XP_016859073.1|ensembl:ENSG00000123983(gene)|ensembl:ENST00000357430(transcript)|ensembl:ENST00000392066(transcript)|ensembl:ENST00000679514(transcript)|ensembl:ENST00000679558(transcript)|ensembl:ENST00000680147(transcript)|ensembl:ENST00000680251(transcript)|ensembl:ENST00000680395(transcript)|ensembl:ENST00000680684(transcript)|ensembl:ENST00000680921(transcript)|ensembl:ENST00000681383(transcript)|ensembl:ENST00000681697(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|mint:O95573|reactome:R-HSA-434313|reactome:R-HSA-75876 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:L5tCBPOlL45uh0aUFi4algZQ5nY9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:O95159 intact:EBI-25592074 intact:EBI-718439|uniprotkb:O14616|uniprotkb:Q9UID0|uniprotkb:A8K7E9|ensembl:ENSP00000294258 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zfpl1_human(display_long)|uniprotkb:Zinc finger protein MCG4(gene name synonym)|uniprotkb:ZFPL1(gene name)|psi-mi:ZFPL1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_006773.2|ensembl:ENSG00000162300(gene)|ensembl:ENST00000294258(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039043|mint:O95159 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:8U/G+YcD/pF1Cg44ghFOW+D8tD89606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:O94766 intact:EBI-25592074 intact:EBI-3917958|uniprotkb:B7ZAB3|uniprotkb:Q9UEP0|uniprotkb:Q96I06|ensembl:ENSP00000265471 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:b3ga3_human(display_long)|uniprotkb:B3GAT3(gene name)|psi-mi:B3GAT3(display_short)|uniprotkb:Beta-1,3-glucuronyltransferase 3(gene name synonym)|uniprotkb:Glucuronosyltransferase I(gene name synonym)|uniprotkb:"UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001275652.1|refseq:NP_036332.2|ensembl:ENSG00000149541(gene)|ensembl:ENST00000265471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0015018"(galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050650"(chondroitin sulfate proteoglycan biosynthetic process)|go:"GO:0050651"(dermatan sulfate proteoglycan biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR005027(Glycosyl transferase, family 43)|interpro:IPR029044|mint:O94766|rcsb pdb:1FGG|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|rcsb pdb:3CU0|reactome:R-HSA-1971475|reactome:R-HSA-3560801|rcsb pdb:1KWS - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:Yay8m8ZubBSmSoywX2Zk/dYNdzA9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:O14975 intact:EBI-25592074 intact:EBI-2801436|uniprotkb:Q53FY6|uniprotkb:A8K2J7|uniprotkb:Q6PF09|ensembl:ENSP00000267842 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:s27a2_human(display_long)|uniprotkb:ACSVL1(gene name synonym)|uniprotkb:FACVL1(gene name synonym)|uniprotkb:FATP2(gene name synonym)|uniprotkb:VLACS(gene name synonym)|uniprotkb:Fatty acid transport protein 2(gene name synonym)|uniprotkb:Fatty-acid-coenzyme A ligase, very long-chain 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Solute carrier family 27 member 2(gene name synonym)|uniprotkb:THCA-CoA ligase(gene name synonym)|uniprotkb:Very long-chain-fatty-acid-CoA ligase(gene name synonym)|uniprotkb:SLC27A2(gene name)|psi-mi:SLC27A2(display_short)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001153101.1|refseq:NP_003636.2|ensembl:ENSG00000140284(gene)|ensembl:ENST00000267842(transcript)|go:"GO:0001561"(fatty acid alpha-oxidation)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0047747"(cholate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR030305|interpro:IPR042099|mint:O14975|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-389599|reactome:R-HSA-6798695|reactome:R-HSA-9033241 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:lOeY1DAlhT5ZfNd5gUhEBBvszws9606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422445 uniprotkb:A8MTT3 intact:EBI-25592074 intact:EBI-20869809|ensembl:ENSP00000380254|ensembl:ENSP00000380403|ensembl:ENSP00000383895|ensembl:ENSP00000384331|ensembl:ENSP00000384813|uniprotkb:A8MUR5 psi-mi:k9n7c7-pro_0000422445(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cebos_human(display_long)|uniprotkb:CEBPZ antisense RNA 1(gene name synonym)|uniprotkb:CEBPZ opposite strand(gene name synonym)|uniprotkb:CEBPZOS(gene name)|psi-mi:CEBPZOS(display_short)|uniprotkb:CEBPZ-AS1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26374966|imex:IM-28441-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000218739(gene)|ensembl:ENST00000392061(transcript)|ensembl:ENST00000397064(transcript)|ensembl:ENST00000397226(transcript)|ensembl:ENST00000402297(transcript)|ensembl:ENST00000406711(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR037764|refseq:NP_001309302.1|refseq:NP_001309303.1|refseq:NP_001309304.1|refseq:NP_001309305.1|refseq:XP_016858595.1|refseq:XP_016858596.1|refseq:XP_016858597.1|refseq:XP_016858598.1 - chain-seq-start:3846|chain-seq-end:3928 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:IrKwW/DkKKm8c15jc8rQZbCGROc1263720 rogid:5v9fW8kybAkjQE12Qk6CcTdC3+89606 rigid:lxTVZSh9qKZ2bcoUTvRFAJpouXM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:P10644 intact:EBI-25592080 intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9Y3A4 intact:EBI-25592080 intact:EBI-7223720|uniprotkb:B2RBG4|uniprotkb:Q8NEY6|uniprotkb:Q8IVY0|intact:MINT-2823375|intact:UNK-5358198|uniprotkb:Q5JZ94|uniprotkb:Q6P4B5|uniprotkb:Q0VAD0|uniprotkb:Q8N5Q3|uniprotkb:Q9Y3H5|uniprotkb:A4FTX2|intact:UNK-5480409|uniprotkb:Q8IVR9|ensembl:ENSP00000321449 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rrp7a_human(display_long)|uniprotkb:CGI-96(orf name)|uniprotkb:RRP7A(gene name)|psi-mi:RRP7A(display_short)|uniprotkb:Gastric cancer antigen Zg14(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_056518.2|ensembl:ENSG00000189306(gene)|ensembl:ENST00000323013(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024326|interpro:IPR034890|interpro:IPR035979|interpro:IPR040446|interpro:IPR040447|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - chain-seq-start:3929|chain-seq-end:4127 comment:mint|comment:homomint figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:8ydFaLpL9ttv+9iZyvaQf3GPWXg9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9BSC4 intact:EBI-25592080 intact:EBI-7001376|uniprotkb:Q53RC9|uniprotkb:Q9H855|uniprotkb:Q96TA5|uniprotkb:Q9H7Y7|uniprotkb:A8K3R5|intact:MINT-3060916|uniprotkb:B4DLV0|ensembl:ENSP00000371101 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nol10_human(display_long)|uniprotkb:NOL10(gene name)|psi-mi:NOL10(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_079170.2|refseq:NP_001248323.1|refseq:NP_001248321.1|ensembl:ENSG00000115761(gene)|ensembl:ENST00000381685(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012580(NUC153)|interpro:IPR036322|interpro:IPR040382|mint:Q9BSC4 - chain-seq-start:3929|chain-seq-end:4127 comment:mint figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:PiblslntTRSvRQnk82fSgtVJbXE9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9Y3B2 intact:EBI-25592080 intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9NY61 intact:EBI-25592080 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q99848 intact:EBI-25592080 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q96GQ7 intact:EBI-25592080 intact:EBI-722051|uniprotkb:A0AVB6|uniprotkb:Q5VXM7|uniprotkb:Q8WYG4|uniprotkb:Q969N7|uniprotkb:Q96F57|uniprotkb:Q96L97|uniprotkb:Q9BWY9|uniprotkb:Q9BXF0|uniprotkb:Q9H990|uniprotkb:Q9NWU3|uniprotkb:Q9P0C2|uniprotkb:Q9UGD6|uniprotkb:B7ZLY1 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ddx27_human(display_long)|uniprotkb:DEAD box protein 27(gene name synonym)|uniprotkb:DDX27(gene name)|psi-mi:DDX27(display_short)|uniprotkb:RHLP(gene name synonym)|uniprotkb:cPERP-F(gene name synonym)|uniprotkb:HSPC259(orf name)|uniprotkb:PP3241(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) interpro:IPR027417|refseq:NP_060365.7|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|mint:Q96GQ7|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome) - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:Z4Dm6lxXyqB18+uPxROJszLWYdE9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q8IY81 intact:EBI-25592080 intact:EBI-744088|uniprotkb:Q8N3A3|uniprotkb:Q8WXX1|uniprotkb:Q9BWM4|uniprotkb:Q9NXT6|uniprotkb:D3DU22|uniprotkb:B2RCA5|ensembl:ENSP00000396673 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:spb1_human(display_long)|uniprotkb:FTSJ3(gene name)|psi-mi:FTSJ3(display_short)|uniprotkb:SB92(orf name)|uniprotkb:Protein ftsJ homolog 3(gene name synonym)|uniprotkb:Putative rRNA methyltransferase 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_060117.3|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR024576|interpro:IPR028589|interpro:IPR029063|mint:Q8IY81|reactome:R-HSA-6791226|ensembl:ENSG00000108592(gene)|ensembl:ENST00000427159(transcript)|go:"GO:0000453"(enzyme-directed rRNA 2'-O-methylation)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008650"("rRNA (uridine-2'-O-)-methyltransferase activity")|go:"GO:0016435"("rRNA (guanine) methyltransferase activity")|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0031167"(rRNA methylation)|go:"GO:0062105"(RNA 2'-O-methyltransferase activity)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR012920(Spb1, C-terminal) - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:KIeyMWn9Zktm5lV7XI7v2bRA8og9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q15050 intact:EBI-25592080 intact:EBI-749186|uniprotkb:Q9BUX8|ensembl:ENSP00000322396 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rrs1_human(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:KIAA0112(gene name synonym)|uniprotkb:RRR(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_055984.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|mint:Q15050|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000179041(gene)|ensembl:ENST00000320270(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome) - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:0Nm9UoIGLBiqOGl0E2BA0S5EXIU9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q13823 intact:EBI-25592080 intact:EBI-1043365|uniprotkb:Q9BWN7|ensembl:ENSP00000362153 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nog2_human(display_long)|uniprotkb:Autoantigen NGP-1(gene name synonym)|uniprotkb:GNL2(gene name)|psi-mi:GNL2(display_short)|uniprotkb:NGP1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000134697(gene)|ensembl:ENST00000373062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q13823|rcsb pdb:6LSS|rcsb pdb:6LU8|refseq:NP_037417.1 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:CgIg/QNhk71SHIhV4iLvIuC/HUo9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9ULX6 intact:EBI-25592080 intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9UHG3 intact:EBI-25592080 intact:EBI-2908417|ensembl:ENSP00000387654|uniprotkb:B7Z9P8|uniprotkb:B2RB14|uniprotkb:O94982|uniprotkb:Q8N4N5|uniprotkb:Q96QM8 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pcyox_human(display_long)|uniprotkb:PCYOX1(gene name)|psi-mi:PCYOX1(display_short)|uniprotkb:KIAA0908(gene name synonym)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Prenylcysteine lyase(gene name synonym)|uniprotkb:UNQ597/PRO1183(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000116005(gene)|ensembl:ENST00000433351(transcript)|go:"GO:0001735"(prenylcysteine oxidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0030327"(prenylated protein catabolic process)|go:"GO:0030328"(prenylcysteine catabolic process)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902476"(chloride transmembrane transport)|interpro:IPR010795(Prenylcysteine lyase)|interpro:IPR017046(Prenylcysteine oxidase)|interpro:IPR036188|mint:Q9UHG3|refseq:NP_057381.3 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:E7WR6qZZuoGqmWQ+CX6PeZX/yEw9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9NTK5 intact:EBI-25592080 intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|uniprotkb:D7EHM2|ensembl:ENSP00000284719 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENST00000284719(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|ensembl:ENSG00000138430(gene) - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9H6R4 intact:EBI-25592080 intact:EBI-2514288|ensembl:ENSP00000297990|uniprotkb:Q5T5M4|uniprotkb:Q8TEZ0|uniprotkb:Q8TEZ1|uniprotkb:Q8TEY9|uniprotkb:Q7L4G6|uniprotkb:Q5T5M3|uniprotkb:Q8N6I0|uniprotkb:Q9H675 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nol6_human(display_long)|uniprotkb:NOL6(gene name)|psi-mi:NOL6(display_short)|uniprotkb:Nucleolar RNA-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000165271(gene)|ensembl:ENST00000297990(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032545"(CURI complex)|go:"GO:0034456"(UTP-C complex)|interpro:IPR005554(Nrap protein)|interpro:IPR035082|interpro:IPR035367|interpro:IPR035368|interpro:IPR035369|interpro:IPR035370|interpro:IPR035371|mint:Q9H6R4|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_075068.2|refseq:NP_631981.2 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:e1Waxlhmq+KTKwHTV13aWEpVF4k9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q9GZL7 intact:EBI-25592080 intact:EBI-2490660|uniprotkb:B3KPA9|uniprotkb:Q96HU0|uniprotkb:Q9NV80|uniprotkb:Q9NYI8|ensembl:ENSP00000261015 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wdr12_human(display_long)|uniprotkb:WDR12(gene name)|psi-mi:WDR12(display_short)|uniprotkb:WD repeat-containing protein 12(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) go:"GO:0007219"(Notch signaling pathway)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR012972(NLE)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR028599|interpro:IPR036322|mint:Q9GZL7|rcsb pdb:6N31|rcsb pdb:6P0Q|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000138442(gene)|ensembl:ENST00000261015(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|refseq:NP_060726.3 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:7qCdIJOJA36eRlrwJA6x0XC/Tqc9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q99547 intact:EBI-25592080 intact:EBI-373187|uniprotkb:B2RAF0|ensembl:ENSP00000258169 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mph6_human(display_long)|uniprotkb:MPHOSPH6(gene name)|psi-mi:MPHOSPH6(display_short)|uniprotkb:MPP6(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_005783.2|ensembl:ENSG00000135698(gene)|ensembl:ENST00000258169(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR019324|mint:Q99547|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-6791226|dip:DIP-31131N - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:B53KiT1Bo6QC3Ckmf28PoKlRRms9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q8TC07 intact:EBI-25592080 intact:EBI-1048247|uniprotkb:B9A6L6|intact:EBI-6190229|uniprotkb:B4DMT9|uniprotkb:J3KNI9|uniprotkb:Q9HA83|intact:EBI-28984447|ensembl:ENSP00000448182 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tbc15_human(display_long)|uniprotkb:TBC1D15(gene name)|psi-mi:TBC1D15(display_short)|uniprotkb:GTPase-activating protein RAB7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001139685.2|refseq:NP_001139686.1|refseq:NP_073608.4|ensembl:ENST00000319106|ensembl:ENSP00000318262|ensembl:ENST00000485960|ensembl:ENSP00000420678|ensembl:ENSP00000448182|ensembl:ENSG00000121749(gene)|ensembl:ENST00000550746(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-HSA-8854214 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:3tlqjLtZ/Bq5H6M00sHIwqNqqw49606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q8NI36 intact:EBI-25592080 intact:EBI-2512413|ensembl:ENSP00000423067|ensembl:ENSP00000479950|uniprotkb:A2RUS4|uniprotkb:Q8N1Q2|uniprotkb:Q68E02 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wdr36_human(display_long)|uniprotkb:WDR36(gene name)|psi-mi:WDR36(display_short)|uniprotkb:T-cell activation WD repeat-containing protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000134987(gene)|ensembl:ENST00000506538(transcript)|ensembl:ENST00000612402(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0007601"(visual perception)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|go:"GO:0050896"(response to stimulus)|interpro:IPR001680(WD40 repeat)|interpro:IPR007319(Small-subunit processome, Utp21)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|refseq:NP_644810.1 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:97Qc0ehUPTjCBcn3gjr0FY8Nnus9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q8N5D0 intact:EBI-25592080 intact:EBI-311222|uniprotkb:Q9NV87|uniprotkb:Q9UPW4|intact:EBI-2559106|uniprotkb:Q5SSC5|uniprotkb:D3DPL5|ensembl:ENSP00000317971 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wdtc1_human(display_long)|uniprotkb:WDTC1(gene name)|psi-mi:WDTC1(display_short)|uniprotkb:KIAA1037(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_055838.2|ensembl:ENSG00000142784(gene)|ensembl:ENST00000319394(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0055082"(cellular chemical homeostasis)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019734|interpro:IPR036322|rcsb pdb:3I7N|reactome:R-HSA-8951664|refseq:XP_011539359.1|refseq:NP_001263181.1|dip:DIP-31627N - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:jAsFFwoAfRkN+OVv32DRidscyi09606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q8IX01 intact:EBI-25592080 intact:EBI-949116|ensembl:ENSP00000337926|ensembl:ENSP00000389380|ensembl:ENSP00000472286|uniprotkb:O15071|uniprotkb:O60369|uniprotkb:Q5JPH7|uniprotkb:Q8WUF7|uniprotkb:C9JI71 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sugp2_human(display_long)|uniprotkb:Arginine/serine-rich-splicing factor 14(gene name synonym)|uniprotkb:SUGP2(gene name)|psi-mi:SUGP2(display_short)|uniprotkb:KIAA0365(gene name synonym)|uniprotkb:SFRS14(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 14(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000064607(gene)|ensembl:ENST00000337018(transcript)|ensembl:ENST00000452918(transcript)|ensembl:ENST00000601879(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR035967|interpro:IPR040169|mint:Q8IX01|rcsb pdb:1X4P|refseq:NP_001017392.2|refseq:NP_055699.2|refseq:XP_016881626.1|refseq:NP_001308626.1 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:hN1zWaoMMufKCQNO9VQ8NPiN0hI9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q7Z4Q2 intact:EBI-25592080 intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|uniprotkb:A8K1N4|ensembl:ENSP00000299192 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_891552.1|ensembl:ENSG00000155393(gene)|ensembl:ENST00000299192(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR016024(Armadillo-type fold)|mint:Q7Z4Q2 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q76FK4 intact:EBI-25592080 intact:EBI-396069|uniprotkb:Q5TCC7|uniprotkb:Q5TCC8|uniprotkb:Q5TCD3|uniprotkb:Q5TCD5|uniprotkb:Q5TCD6|uniprotkb:Q5TCD7|uniprotkb:Q76D35|uniprotkb:Q7L3E2|uniprotkb:Q9H586|uniprotkb:Q9H795|uniprotkb:Q9H7W7|uniprotkb:Q9H9J6|uniprotkb:Q9NWA4|uniprotkb:Q9NWM4|ensembl:ENSP00000401177|ensembl:ENSP00000441140 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nol8_human(display_long)|uniprotkb:Nucleolar protein Nop132(gene name synonym)|uniprotkb:NOL8(gene name)|psi-mi:NOL8(display_short)|uniprotkb:C9orf34(gene name synonym)|uniprotkb:NOP132(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_060418.4|refseq:XP_011517126.1|ensembl:ENSG00000198000(gene)|ensembl:ENST00000442668(transcript)|ensembl:ENST00000545558(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034138|interpro:IPR035979|refseq:NP_001243323.1|refseq:XP_006717229.1|refseq:XP_006717230.1|refseq:XP_006717232.1|refseq:XP_006717233.1|refseq:NP_001317651.1|refseq:XP_016870365.1 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:tKGGHXKwb9YuzARkLi19za57xZM9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q16531 intact:EBI-25592080 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q15269 intact:EBI-25592080 intact:EBI-722224|uniprotkb:Q96A77|uniprotkb:B2RAG8|ensembl:ENSP00000291576 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pwp2_human(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:PWP2H(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_005040.2|refseq:XP_006723973.1|refseq:XP_011507205.1|ensembl:ENSG00000241945(gene)|ensembl:ENST00000291576(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:PYs2LKd3EMjAnp0engZvZn0CeBo9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q14146 intact:EBI-25592080 intact:EBI-9996029|uniprotkb:Q5VYC9|ensembl:ENSP00000258243 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:urb2_human(display_long)|uniprotkb:URB2(gene name)|psi-mi:URB2(display_short)|uniprotkb:KIAA0133(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_055592.2|refseq:NP_001300950.1|ensembl:ENSG00000135763(gene)|ensembl:ENST00000258243(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0016235"(aggresome)|go:"GO:0030496"(midbody)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR018849 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:BhDO5U3/iVSj0xlncOQpkGRl+gc9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q13206 intact:EBI-25592080 intact:EBI-2514399|ensembl:ENSP00000314348|uniprotkb:Q5BJD8|uniprotkb:B2RCQ3 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ddx10_human(display_long)|uniprotkb:DDX10(gene name)|psi-mi:DDX10(display_short)|uniprotkb:DEAD box protein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000178105(gene)|ensembl:ENST00000322536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0097065"(anterior head development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|mint:Q13206|rcsb pdb:2PL3|refseq:NP_004389.2 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:MMAbABrYQHlYDyPsagT7oY92Z3M9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q12788 intact:EBI-25592080 intact:EBI-715766|uniprotkb:Q59GD6|uniprotkb:Q8IVB7|intact:EBI-749106|uniprotkb:Q96A78|ensembl:ENSP00000454836 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tbl3_human(display_long)|uniprotkb:WD repeat-containing protein SAZD(gene name synonym)|uniprotkb:TBL3(gene name)|psi-mi:TBL3(display_short)|uniprotkb:SAZD(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_006444.2|ensembl:ENSG00000183751(gene)|ensembl:ENST00000568546(transcript)|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013934(Small-subunit processome, Utp13)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q12788|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:XFWYZxef3kNBYeTaoSBWEXQoF/M9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:Q03701 intact:EBI-25592080 intact:EBI-1046778|uniprotkb:Q8NE75|ensembl:ENSP00000234170 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cebpz_human(display_long)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:CEBPZ(gene name)|psi-mi:CEBPZ(display_short)|uniprotkb:CBF2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_005751.2|ensembl:ENSG00000115816(gene)|ensembl:ENST00000234170(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|mint:Q03701 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:4VX4KR6JGLaEMorRYbfPRaMgGuE9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:P51116 intact:EBI-25592080 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:P51114 intact:EBI-25592080 intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:P42285 intact:EBI-25592080 intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:O95707 intact:EBI-25592080 intact:EBI-366477|uniprotkb:Q5XKL7|uniprotkb:Q9UQQ3|uniprotkb:Q6FHW9|ensembl:ENSP00000465213 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rpp29_human(display_long)|uniprotkb:POP4(gene name)|psi-mi:POP4(display_short)|uniprotkb:RPP29(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_006618.1|ensembl:ENSG00000105171(gene)|ensembl:ENST00000585603(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030677"(ribonuclease P complex)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|interpro:IPR002730(Ribonuclease P/MRP, p29 subunit, eukaryotic/archaeal)|interpro:IPR016848(Ribonuclease P/MRP, p29 subunit, eukaryotic)|interpro:IPR023534|interpro:IPR036980|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:4cCOti0t03LPAs0kk7VKGpniBOg9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:O95373 intact:EBI-25592080 intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:O60287 intact:EBI-25592080 intact:EBI-1762349|uniprotkb:D3DSE5|uniprotkb:Q96NX1|uniprotkb:Q9NYQ1|ensembl:ENSP00000372199 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:npa1p_human(display_long)|uniprotkb:URB1(gene name)|psi-mi:URB1(display_short)|uniprotkb:C21orf108(gene name synonym)|uniprotkb:KIAA0539(gene name synonym)|uniprotkb:NPA1(gene name synonym)|uniprotkb:URB1 ribosome biogenesis 1 homolog(gene name synonym)|uniprotkb:NOP254(gene name synonym)|uniprotkb:Nucleolar protein 254 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_055640.2|interpro:IPR021714|interpro:IPR032436|interpro:IPR039844|ensembl:ENSG00000142207(gene)|ensembl:ENST00000382751(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR016024(Armadillo-type fold) - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:tolq2rVG0N5qy3qGiIkPj8xtVis9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422446 uniprotkb:O15381 intact:EBI-25592080 intact:EBI-721638|uniprotkb:Q96EM7|uniprotkb:B4DMC4|uniprotkb:B4DP98|ensembl:ENSP00000281701 psi-mi:k9n7c7-pro_0000422446(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nvl_human(display_long)|uniprotkb:NVL(gene name)|psi-mi:NVL(display_short)|uniprotkb:NVL2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375013|imex:IM-28441-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_002524.2|refseq:NP_996671.1|refseq:NP_001230075.1|refseq:NP_001230076.1|ensembl:ENSG00000143748(gene)|ensembl:ENST00000281701(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:1904749"(regulation of protein localization to nucleolus)|go:"GO:1990275"(preribosome binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR031996|interpro:IPR038100|interpro:IPR041569|mint:O15381|rcsb pdb:2X8A|rcsb pdb:6RO1 - chain-seq-start:3929|chain-seq-end:4127 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:aNT0rd2MwJasTBwTfZfd4JvJXqA1263720 rogid:3xAHor7LoQCGSzrRQWhKaEuqd9A9606 rigid:kYrrB3AYOndO2A5OCUbTOMwT/KU false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:Q9BU61 intact:EBI-25592866 intact:EBI-2114801|ensembl:ENSP00000323076 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198 - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:Q96PM5 intact:EBI-25592866 intact:EBI-947779|uniprotkb:C7E542|uniprotkb:C7E543|uniprotkb:Q96PR5|uniprotkb:C7E541|uniprotkb:Q59GN7|uniprotkb:Q86X26|uniprotkb:B3KRG3|uniprotkb:E7EMC8|uniprotkb:E7ETW5|uniprotkb:J3KPI0|uniprotkb:D3YRV2|uniprotkb:Q2KN33|ensembl:ENSP00000321239 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zn363_human(display_long)|uniprotkb:Zinc finger protein 363(gene name synonym)|uniprotkb:CH-rich-interacting match with PLAG1(gene name synonym)|uniprotkb:Androgen receptor N-terminal-interacting protein(gene name synonym)|uniprotkb:p53-induced RING-H2 protein(gene name synonym)|uniprotkb:RING finger protein 199(gene name synonym)|uniprotkb:RCHY1(gene name)|psi-mi:RCHY1(display_short)|uniprotkb:ARNIP(gene name synonym)|uniprotkb:CHIMP(gene name synonym)|uniprotkb:ZNF363(gene name synonym)|uniprotkb:PIRH2(gene name synonym)|uniprotkb:RNF199(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase Pirh2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RCHY1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001009922.1|refseq:NP_056251.2|refseq:NP_001265465.1|refseq:NP_001265466.1|refseq:NP_001265467.1|dip:DIP-43981N|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070987"(error-free translesion synthesis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR008913(Zinc finger, CHY-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017921|interpro:IPR037274|interpro:IPR037275|interpro:IPR039512|mint:Q96PM5|rcsb pdb:2JRJ|rcsb pdb:2K2C|rcsb pdb:2K2D|reactome:R-HSA-110320|reactome:R-HSA-983168|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000163743(gene)|ensembl:ENST00000324439(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0002039"(p53 binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042803"(protein homodimerization activity) - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:3khPuhFXlOrWR6KjF+9av4mJAMQ9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:Q8IWP9 intact:EBI-25592866 intact:EBI-355471|uniprotkb:Q9Y430|uniprotkb:Q32NC7|uniprotkb:Q66K67|uniprotkb:Q96E23|uniprotkb:E1P591 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cc28a_human(display_long)|uniprotkb:CCDC28A(gene name)|psi-mi:CCDC28A(display_short)|uniprotkb:C6orf80(gene name synonym)|uniprotkb:CCRL1AP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) interpro:IPR025271|refseq:NP_056254.1 - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:P6RRe4x1NvXrcimUTKQI5q9ifb89606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:Q86YT6 intact:EBI-25592866 intact:EBI-2129148|uniprotkb:Q2TB37|uniprotkb:Q68D01|uniprotkb:Q6YI51|uniprotkb:Q8NBY0|uniprotkb:Q8TCB5|uniprotkb:Q8TCL7|uniprotkb:Q9P2M3|uniprotkb:B0YJ38|ensembl:ENSP00000261537 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mib1_human(display_long)|uniprotkb:MIB1(gene name)|psi-mi:MIB1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:KIAA1323(gene name synonym)|uniprotkb:ZZANK2(gene name synonym)|uniprotkb:Mind bomb homolog 1(gene name synonym)|uniprotkb:DAPK-interacting protein 1(gene name synonym)|uniprotkb:Zinc finger ZZ type with ankyrin repeat domain protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_065825.1|ensembl:ENSG00000101752(gene)|ensembl:ENST00000261537(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001947"(heart looping)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR010606(Mib-herc2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|interpro:IPR043145|mint:Q86YT6|rcsb pdb:4TSE|rcsb pdb:4XI6|rcsb pdb:4XI7|rcsb pdb:4XIB|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507 - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:+DhNmSTvuXexGhi2FyEuBv4pBiw9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:Q6SZW1 intact:EBI-25592866 intact:EBI-11693532|uniprotkb:O60277|uniprotkb:Q7LGG3|uniprotkb:Q9NXY5|ensembl:ENSP00000468032 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sarm1_human(display_long)|uniprotkb:Sterile alpha and Armadillo repeat protein(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 2(gene name synonym)|uniprotkb:Tir-1 homolog(gene name synonym)|uniprotkb:SARM1(gene name)|psi-mi:SARM1(display_short)|uniprotkb:KIAA0524(gene name synonym)|uniprotkb:SAMD2(gene name synonym)|uniprotkb:SARM(gene name synonym)|uniprotkb:"NADP(+) hydrolase SARM1"(gene name synonym)|uniprotkb:Sterile alpha and TIR motif-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_055892.2|ensembl:ENSG00000004139(gene)|ensembl:ENST00000585482(transcript)|go:"GO:0003953"(NAD+ nucleosidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0009749"(response to glucose)|go:"GO:0019677"(NAD catabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034128"(negative regulation of MyD88-independent toll-like receptor signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048678"(response to axon injury)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR000157(Toll-Interleukin receptor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035897|interpro:IPR039184|rcsb pdb:6O0Q|rcsb pdb:6O0R|rcsb pdb:6O0S|rcsb pdb:6O0T|rcsb pdb:6O0U|rcsb pdb:6O0V|rcsb pdb:6O1B|rcsb pdb:6QWV|rcsb pdb:6WPK|rcsb pdb:6ZFX|rcsb pdb:6ZG0|rcsb pdb:6ZG1|rcsb pdb:7ANW|rcsb pdb:7CM5|rcsb pdb:7CM6|rcsb pdb:7CM7|rcsb pdb:7DJT|rcsb pdb:7LD0|reactome:R-HSA-166166|reactome:R-HSA-168164|reactome:R-HSA-936964|reactome:R-HSA-937041|reactome:R-HSA-937072 - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:n7sfGqChRoQGfwzfXUJV8AY3jDY9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:Q5SW79 intact:EBI-25592866 intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:P62310 intact:EBI-25592866 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:P49419 intact:EBI-25592866 intact:EBI-726842|uniprotkb:O14619|uniprotkb:Q6IPU8|uniprotkb:B4DIC7|uniprotkb:Q9BUL4|uniprotkb:B2R669|uniprotkb:B4DMA0|uniprotkb:E7EPT3|ensembl:ENSP00000387123 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:al7a1_human(display_long)|uniprotkb:Betaine aldehyde dehydrogenase(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 7 member A1(gene name synonym)|uniprotkb:Antiquitin-1(gene name synonym)|uniprotkb:ALDH7A1(gene name)|psi-mi:ALDH7A1(display_short)|uniprotkb:ATQ1(gene name synonym)|uniprotkb:Delta1-piperideine-6-carboxylate dehydrogenase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001173.2|refseq:NP_001188306.1|refseq:NP_001189333.2|ensembl:ENSG00000164904(gene)|ensembl:ENST00000409134(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004043"(L-aminoadipate-semialdehyde dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008802"(betaine-aldehyde dehydrogenase activity)|go:"GO:0019285"(glycine betaine biosynthetic process from choline)|go:"GO:0042426"(choline catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|interpro:IPR044638|rcsb pdb:2J6L|rcsb pdb:4X0T|rcsb pdb:4X0U|rcsb pdb:4ZUK|rcsb pdb:4ZUL|rcsb pdb:4ZVW|rcsb pdb:4ZVX|rcsb pdb:4ZVY|rcsb pdb:6O4B|rcsb pdb:6O4C|rcsb pdb:6O4E|rcsb pdb:6O4F|rcsb pdb:6O4G|rcsb pdb:6O4H|rcsb pdb:6O4I|rcsb pdb:6O4K|rcsb pdb:6O4L|rcsb pdb:6U2X|rcsb pdb:6V0Z|reactome:R-HSA-6798163|reactome:R-HSA-71064|rcsb pdb:6O4D - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:3UZ9c2xuwZ9b8vbbPbB77aRoKbg9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:P41250 intact:EBI-25592866 intact:EBI-724143|uniprotkb:B3KQA2|uniprotkb:B4DIA0|ensembl:ENSP00000373918|uniprotkb:Q969Y1|intact:EBI-25629666|uniprotkb:A0A090N8G0 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gars_human(display_long)|uniprotkb:GARS1(gene name)|psi-mi:GARS1(display_short)|uniprotkb:Diadenosine tetraphosphate synthetase(gene name synonym)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_002038.2|rcsb pdb:4KQE|rcsb pdb:4KR2|rcsb pdb:2ZT6|rcsb pdb:4KR3|rcsb pdb:4QEI|rcsb pdb:5E6M|reactome:R-HSA-379716|rcsb pdb:2ZT7|reactome:R-HSA-379726|rcsb pdb:2ZT8|rcsb pdb:2ZXF|ensembl:ENSG00000106105(gene)|ensembl:ENST00000389266(transcript)|go:"GO:0004081"("bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity")|go:"GO:0004820"(glycine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006426"(glycyl-tRNA aminoacylation)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016740"(transferase activity)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070150"(mitochondrial glycyl-tRNA aminoacylation)|interpro:IPR000738(WHEP-TRS)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002315(Glycyl-tRNA synthetase, alpha2 dimer)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR027031|interpro:IPR033731|interpro:IPR036621|mint:P41250|rcsb pdb:2PME|rcsb pdb:2PMF|rcsb pdb:2Q5H|rcsb pdb:2Q5I|rcsb pdb:2ZT5|refseq:NP_001303701.1|dip:DIP-50471N - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:bBlAPOMGXKsEvu0DxGKJJLjDI1s9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:P38606 intact:EBI-25592866 intact:EBI-1054757|intact:EBI-10982175|uniprotkb:Q53YD9|uniprotkb:Q96DY6|uniprotkb:Q9UHY3|uniprotkb:B2RBR8|uniprotkb:B7Z1R5|uniprotkb:D3DN75|ensembl:ENSP00000273398 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vata_human(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Vacuolar ATPase isoform VA68(gene name synonym)|uniprotkb:ATP6V1A(gene name)|psi-mi:ATP6V1A(display_short)|uniprotkb:ATP6A1(gene name synonym)|uniprotkb:ATP6V1A1(gene name synonym)|uniprotkb:VPP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001681.2|ensembl:ENSG00000114573(gene)|ensembl:ENST00000273398(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P38606|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712 - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:GqPRFwsl5tDH83kpE8Al7NiYWrI9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:P21281 intact:EBI-25592866 intact:EBI-4290814|uniprotkb:Q14544|uniprotkb:Q15859|uniprotkb:B2R5Z3|uniprotkb:D3DSQ5|uniprotkb:Q96IR0|ensembl:ENSP00000276390 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vatb2_human(display_long)|uniprotkb:ATP6V1B2(gene name)|psi-mi:ATP6V1B2(display_short)|uniprotkb:ATP6B2(gene name synonym)|uniprotkb:VPP3(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:HO57(gene name synonym)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_001684.2|ensembl:ENSG00000147416(gene)|ensembl:ENST00000276390(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P21281|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|dip:DIP-47433N - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:CikZS+29TqYLiADRWgVESqCpg689606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7C7-PRO_0000422447 uniprotkb:O00233 intact:EBI-25592866 intact:EBI-750973|uniprotkb:Q9BQ42|uniprotkb:G3V1Q6|uniprotkb:B2RD35|intact:EBI-28988356|ensembl:ENSP00000440485 psi-mi:k9n7c7-pro_0000422447(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:psmd9_human(display_long)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)|uniprotkb:PSMD9(gene name)|psi-mi:PSMD9(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375055|imex:IM-28441-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25591996(chain-parent) refseq:NP_002804.2|refseq:NP_001248329.1|ensembl:ENST00000537407|ensembl:ENSP00000445058|ensembl:ENSP00000440485|ensembl:ENST00000542602|ensembl:ENSP00000443772|ensembl:ENSG00000110801(gene)|ensembl:ENST00000541212(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|go:"GO:0003713"(transcription coactivator activity) - chain-seq-start:4128|chain-seq-end:4237 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:DGsjN5ZMBP9q760WMqx5QQ9wzyo1263720 rogid:OkUTrgO5lFTumVtMd+3vZTf3TPc9606 rigid:HOrlwASZzVg/FO2aMYDsslVDNtE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:Q9UBE0 intact:EBI-26375083 intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:Q8N129 intact:EBI-26375083 intact:EBI-723824|uniprotkb:Q8WUN9|ensembl:ENSP00000262932 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:cnpy4_human(display_long)|uniprotkb:CNPY4(gene name)|psi-mi:CNPY4(display_short)|uniprotkb:PSEC0237(orf name)|uniprotkb:UNQ1909/PRO4354(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) refseq:NP_689968.1|ensembl:ENSG00000166997(gene)|ensembl:ENST00000262932(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR021852 - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:Y6UmbDv+M2D5b5FeOC5YYJBanVs9606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:Q14145 intact:EBI-26375083 intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:P54727 intact:EBI-26375083 intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|ensembl:ENSP00000350708|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) refseq:NP_002865.1|refseq:NP_001231653.1|ensembl:ENSG00000119318(gene)|ensembl:ENST00000358015(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|interpro:IPR029071|dip:DIP-39944N - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:P29144 intact:EBI-26375083 intact:EBI-1044672|uniprotkb:Q5VZU8|ensembl:ENSP00000365233 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:tpp2_human(display_long)|uniprotkb:Tripeptidyl-peptidase II(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:TPP2(gene name)|psi-mi:TPP2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) refseq:NP_003282.2|ensembl:ENSG00000134900(gene)|ensembl:ENST00000376065(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022229|interpro:IPR022398|interpro:IPR023828|interpro:IPR034051|interpro:IPR036852|mint:P29144|reactome:R-HSA-983168|refseq:NP_001317517.1|dip:DIP-50761N - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:I+B6XApXumvX26aR5AdMhkhZVc49606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:P28482 intact:EBI-26375083 intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842 - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:odzhd70I/8uWedx0+gF38lhe60I9606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:Q9NQH7 intact:EBI-26375083 intact:EBI-1171467|uniprotkb:Q6I9V9|uniprotkb:Q8NDA6|uniprotkb:Q9BV27|uniprotkb:Q9BVH0|uniprotkb:B7Z790|uniprotkb:B7Z7B2|uniprotkb:B2R9G1|intact:EBI-2562323|ensembl:ENSP00000349658 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:xpp3_human(display_long)|uniprotkb:Aminopeptidase P3(gene name synonym)|uniprotkb:XPNPEP3(gene name)|psi-mi:XPNPEP3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) refseq:NP_071381.1|ensembl:ENSG00000196236(gene)|ensembl:ENST00000357137(transcript)|go:"GO:0003094"(glomerular filtration)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0016485"(protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR007865(Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal)|interpro:IPR029149|interpro:IPR036005|rcsb pdb:5X49|interpro:IPR000994(Peptidase M24, catalytic core) - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:hRjwsoqTVtJ1YTaVzYWomQGmJOE9606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:P27361 intact:EBI-26375083 intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species) - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:P15531 intact:EBI-26375083 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N796 uniprotkb:P13489 intact:EBI-26375083 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:orf3_mers1(display_long)|uniprotkb:ORF3(gene name)|psi-mi:ORF3(display_short) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375074|imex:IM-28441-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044165"(host cell endoplasmic reticulum) refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:gj7tNtVmurD3uEXIF1H0ETVEyQ01263720 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 rigid:EMtkd502r4efAwtp7VTmqOOqrWA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q96G21 intact:EBI-26375106 intact:EBI-8641721|ensembl:ENSP00000259239|intact:MINT-3052989|intact:MINT-8163231|uniprotkb:Q3ZTT3 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:imp4_human(display_long)|uniprotkb:BXDC4(gene name synonym)|uniprotkb:IMP4(gene name)|psi-mi:IMP4(display_short)|uniprotkb:Brix domain-containing protein 4(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000136718(gene)|ensembl:ENST00000259239(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030684"(preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|go:"GO:0042134"(rRNA primary transcript binding)|interpro:IPR007109(Brix)|interpro:IPR044281|mint:Q96G21|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001307233.1|refseq:NP_001307234.1|refseq:NP_001307235.1|refseq:NP_001307236.1|refseq:NP_001307238.1|refseq:NP_001307239.1|refseq:NP_001307240.1|refseq:NP_219484.1 - - function:"Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing"|comment:mint figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:O220J7eEl0dgQmdVSttk/TMtY4Y9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q96EU6 intact:EBI-26375106 intact:EBI-7851295|ensembl:ENSP00000244496|uniprotkb:Q9P0C8|uniprotkb:Q9BRF6|intact:MINT-4830054 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rrp36_human(display_long)|uniprotkb:RRP36(gene name)|psi-mi:RRP36(display_short)|uniprotkb:C6orf153(gene name synonym)|uniprotkb:HSPC253(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000124541(gene)|ensembl:ENST00000244496(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030686"(90S preribosome)|refseq:NP_001316633.1|refseq:NP_149103.1|interpro:IPR009292(Protein of unknown function DUF947)|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0042274"(ribosomal small subunit biogenesis) - - comment:mint|comment:homomint figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:yeUKtYpXGzZEYOzKTsKdjaMA3Vk9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q86XZ4 intact:EBI-26375106 intact:EBI-6164306|ensembl:ENSP00000326841|ensembl:ENSP00000447947|ensembl:ENSP00000448228|uniprotkb:A8K8G9|uniprotkb:Q9H7D4|uniprotkb:Q9H8Y7|uniprotkb:Q9H8Z8 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:spas2_human(display_long)|uniprotkb:SPATS2(gene name)|psi-mi:SPATS2(display_short)|uniprotkb:SCR59(gene name synonym)|uniprotkb:SPATA10(gene name synonym)|uniprotkb:Serine-rich spermatocytes and round spermatid 59 kDa protein(gene name synonym)|uniprotkb:p59scr(gene name synonym)|uniprotkb:Nbla00526(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000123352(gene)|ensembl:ENST00000321898(transcript)|ensembl:ENST00000552918(transcript)|ensembl:ENST00000553127(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR009816(Protein of unknown function DUF1387)|refseq:NP_001280214.1|refseq:NP_001280215.1|refseq:XP_011536993.1|refseq:XP_011536992.1|refseq:NP_075559.2 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:6yU6PMUIkrqHX2k+E5+pPJZcKB49606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9Y3B7 intact:EBI-26375106 intact:EBI-5453723|ensembl:ENSP00000308897|uniprotkb:A8K219|uniprotkb:Q32P46|uniprotkb:Q96Q73|uniprotkb:A6NLT0 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rm11_human(display_long)|uniprotkb:MRPL11(gene name)|psi-mi:MRPL11(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL11m(gene name synonym)|uniprotkb:CGI-113(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000174547(gene)|ensembl:ENST00000310999(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020784|interpro:IPR036769|interpro:IPR036796|mint:Q9Y3B7|refseq:NP_057134.1|refseq:NP_733934.1|refseq:NP_733935.1|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:eTr4vzze0vg1fxw97n9C/lXYssU9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P82933 intact:EBI-26375106 intact:EBI-721385|intact:EBI-1049991|uniprotkb:Q6PG40|ensembl:ENSP00000258455 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt09_human(display_long)|uniprotkb:MRPS9(gene name)|psi-mi:MRPS9(display_short)|uniprotkb:RPMS9(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS9m(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_872578.1|ensembl:ENSG00000135972(gene)|ensembl:ENST00000258455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P82933|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSE - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:XNB4GL84eYgYFEB3WxOtoD3Ub989606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P82914 intact:EBI-26375106 intact:EBI-2880040|ensembl:ENSP00000362208|uniprotkb:Q9H2K1|uniprotkb:B2RD82 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt15_human(display_long)|uniprotkb:MRPS15(gene name)|psi-mi:MRPS15(display_short)|uniprotkb:RPMS15(gene name synonym)|uniprotkb:DC37(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS15m(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:6ZSA|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000116898(gene)|ensembl:ENST00000373116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR005290(Ribosomal protein S15, bacterial-type)|interpro:IPR009068(S15/NS1, RNA-binding)|mint:P82914|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|refseq:NP_112570.2 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:By026WhG4m+ZHrGZyVjtJDs+p3g9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9Y3A2 intact:EBI-26375106 intact:EBI-2876697|ensembl:ENSP00000362105|uniprotkb:B4DJC6|uniprotkb:Q9BS98|uniprotkb:Q9NS31|uniprotkb:Q5VT93|intact:EBI-2963233|uniprotkb:A8K785|uniprotkb:D3DPT7 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:utp11_human(display_long)|uniprotkb:HDCMB12P(orf name)|uniprotkb:UTP11(gene name)|psi-mi:UTP11(display_short)|uniprotkb:UTP11-like protein(gene name synonym)|uniprotkb:UTP11L(gene name synonym)|uniprotkb:CGI-94(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000183520(gene)|ensembl:ENST00000373014(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR007144(Small-subunit processome, Utp11)|mint:Q9Y3A2|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_057121.2 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:JTS/jMbRZE3NifB95Nqh0foDUKI9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9Y399 intact:EBI-26375106 intact:EBI-2880048|intact:EBI-28977422|ensembl:ENSP00000241600|ensembl:ENSP00000360850|uniprotkb:Q5T899|uniprotkb:Q9BSQ4 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt02_human(display_long)|uniprotkb:MRPS2(gene name)|psi-mi:MRPS2(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:CGI-91(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6RW5|ensembl:ENST00000241600(transcript)|ensembl:ENST00000371785(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0061668"(mitochondrial ribosome assembly)|ensembl:ENSG00000122140(gene)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|mint:Q9Y399|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|ensembl:ENSP00000241600|ensembl:ENSP00000360850|refseq:NP_057118.1 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:tlWj8Un0CmbnBQtZMYlJpvIpc/09606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9Y2Q9 intact:EBI-26375106 intact:EBI-5325249|ensembl:ENSP00000276585|uniprotkb:B2RDZ7|uniprotkb:Q96Q21 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt28_human(display_long)|uniprotkb:Mitochondrial small ribosomal subunit protein bS1m(gene name synonym)|uniprotkb:HSPC007(orf name)|uniprotkb:MRPS28(gene name)|psi-mi:MRPS28(display_short)|uniprotkb:MRPS35(gene name synonym)|uniprotkb:28S ribosomal protein S35, mitochondrial(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENST00000276585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR019375|mint:Q9Y2Q9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|ensembl:ENSG00000147586(gene)|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_054737.1 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:E78l52n5CxYuz9U1JoMSG5jJjMA9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9Y291 intact:EBI-26375106 intact:EBI-2688704|ensembl:ENSP00000320567|ensembl:ENSP00000376732|ensembl:ENSP00000417287|ensembl:ENSP00000418451 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt33_human(display_long)|uniprotkb:MRPS33(gene name)|psi-mi:MRPS33(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS33(gene name synonym)|uniprotkb:CGI-139(orf name)|uniprotkb:PTD003(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_057155.1|refseq:NP_444263.1|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|ensembl:ENSG00000090263(gene)|ensembl:ENST00000324787(transcript)|ensembl:ENST00000393008(transcript)|ensembl:ENST00000469351(transcript)|ensembl:ENST00000496958(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR013219(Ribosomal protein S27, mitochondrial)|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:lKeun672/ySI/pp5aA7KfONA2wM9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9UPY3 intact:EBI-26375106 intact:EBI-395506|uniprotkb:O95943|uniprotkb:Q9UQ02|uniprotkb:A7E2D3|ensembl:ENSP00000343745|ensembl:ENSP00000376783|ensembl:ENSP00000435681|ensembl:ENSP00000437256|uniprotkb:E0AD28|uniprotkb:B3KRG4 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:dicer_human(display_long)|uniprotkb:DICER1(gene name)|psi-mi:DICER1(display_short)|uniprotkb:DICER(gene name synonym)|uniprotkb:HERNA(gene name synonym)|uniprotkb:KIAA0928(gene name synonym)|uniprotkb:Helicase with RNase motif(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_085124.2|refseq:NP_803187.1|refseq:NP_001182502.1|refseq:XP_011534901.1|refseq:XP_011534902.1|refseq:XP_011534903.1|refseq:XP_011534904.1|ensembl:ENSG00000100697(gene)|ensembl:ENST00000343455(transcript)|ensembl:ENST00000393063(transcript)|ensembl:ENST00000526495(transcript)|ensembl:ENST00000527414(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033167"(ARC complex)|go:"GO:0033168"(obsolete conversion of ds siRNA to ss siRNA involved in RNA interference)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0036404"(obsolete conversion of ds siRNA to ss siRNA)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|mint:Q9UPY3|rcsb pdb:2EB1|rcsb pdb:4NGB|rcsb pdb:4NGC|rcsb pdb:4NGD|rcsb pdb:4NGF|rcsb pdb:4NGG|rcsb pdb:4NH3|rcsb pdb:4NH5|rcsb pdb:4NH6|rcsb pdb:4NHA|rcsb pdb:4WYQ|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|reactome:R-HSA-203927|reactome:R-HSA-426486|go:"GO:0035280"(miRNA loading onto RISC)|reactome:R-HSA-9708296|refseq:NP_001258211.1|refseq:NP_001278557.1|refseq:XP_016876609.1|refseq:XP_016876610.1|dip:DIP-29664N - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:RhSXQEEvS9b0IOvnrPYhRd0MzI09606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9UL40 intact:EBI-26375106 intact:EBI-2462313|uniprotkb:B7Z367|uniprotkb:Q68CV9|uniprotkb:Q6ZMW1|ensembl:ENSP00000350869 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:zn346_human(display_long)|uniprotkb:ZNF346(gene name)|psi-mi:ZNF346(display_short)|uniprotkb:JAZ(gene name synonym)|uniprotkb:Just another zinc finger protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001295142.1|refseq:NP_001295143.1|refseq:NP_001295148.1|refseq:NP_001295152.1|refseq:NP_036411.1|refseq:XP_016864784.1|refseq:XP_016864785.1|ensembl:ENSG00000113761(gene)|ensembl:ENST00000358149(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0035198"(miRNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2MKD|rcsb pdb:2MKN - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:bK/y4NYSSsa1tcNjtbmsEmkSp7Q9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9UHA3 intact:EBI-26375106 intact:EBI-749321|uniprotkb:Q561V8|uniprotkb:Q8N6S8|uniprotkb:Q96B04|uniprotkb:Q96C76|uniprotkb:Q96HJ1|uniprotkb:B2RD72|ensembl:ENSP00000260443 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rlp24_human(display_long)|uniprotkb:Ribosomal protein L24-like(gene name synonym)|uniprotkb:RSL24D1(gene name)|psi-mi:RSL24D1(display_short)|uniprotkb:RPL24L(gene name synonym)|uniprotkb:My024(orf name)|uniprotkb:C15orf15(gene name synonym)|uniprotkb:Ribosomal L24 domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_057388.1|ensembl:ENSG00000137876(gene)|ensembl:ENST00000260443(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006412"(translation)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023438|interpro:IPR023442|interpro:IPR038630|mint:Q9UHA3|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0022625"(cytosolic large ribosomal subunit) - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:dP0x5J6G4bPc/7sbV1LIxLNLDn09606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9P015 intact:EBI-26375106 intact:EBI-2371967|uniprotkb:Q96Q54|uniprotkb:Q9H0Y1|ensembl:ENSP00000260102 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rm15_human(display_long)|uniprotkb:MRPL15(gene name)|psi-mi:MRPL15(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL15m(gene name synonym)|uniprotkb:HSPC145(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_054894.1|ensembl:ENSG00000137547(gene)|ensembl:ENST00000260102(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR005749(Ribosomal protein L15, bacterial-type)|interpro:IPR021131|interpro:IPR030878|interpro:IPR036227|mint:Q9P015|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSA - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:efJei4RFNcTx2MqyMwdu7EXO1c09606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9HC52 intact:EBI-26375106 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9H6S0 intact:EBI-26375106 intact:EBI-1057466|uniprotkb:B2RP66|ensembl:ENSP00000161863 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:ytdc2_human(display_long)|uniprotkb:YTHDC2(gene name)|psi-mi:YTHDC2(display_short)|uniprotkb:YTH domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_073739.3|ensembl:ENSG00000047188(gene)|ensembl:ENST00000161863(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007286"(spermatid development)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048599"(oocyte development)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051729"(germline cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR007275(YT521-B-like protein)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031083|interpro:IPR034083|interpro:IPR036770|interpro:IPR036867|mint:Q9H6S0|rcsb pdb:2YU6|rcsb pdb:6K6U|refseq:XP_016865219.1 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:8J8b1Q3F6rfXUwtp7EOeU2y89Lc9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9H6F5 intact:EBI-26375106 intact:EBI-721289|uniprotkb:B4DY99|ensembl:ENSP00000227520 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:ccd86_human(display_long)|uniprotkb:Cytokine-induced protein with coiled-coil domain(gene name synonym)|uniprotkb:CYCLON(gene name synonym)|uniprotkb:CCDC86(gene name)|psi-mi:CCDC86(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_077003.1|ensembl:ENSG00000110104(gene)|ensembl:ENST00000227520(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR005579(Cgr1)|interpro:IPR026570|mint:Q9H6F5 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:dRd5UWPzAehh8OFqkWrMMCnYYug9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9BXR0 intact:EBI-26375106 intact:EBI-716832|uniprotkb:Q96BQ4|uniprotkb:Q9BXQ9|uniprotkb:B4DFM7|ensembl:ENSP00000250237 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:tgt_human(display_long)|uniprotkb:tRNA-guanine transglycosylase(gene name synonym)|uniprotkb:Guanine insertion enzyme(gene name synonym)|uniprotkb:QTRT1(gene name)|psi-mi:QTRT1(display_short)|uniprotkb:TGT(gene name synonym)|uniprotkb:TGUT(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_112486.1|ensembl:ENSG00000213339(gene)|ensembl:ENST00000250237(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006400"(tRNA modification)|go:"GO:0008479"(queuine tRNA-ribosyltransferase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0101030"(tRNA-guanine transglycosylation)|interpro:IPR002616(Queuine/other tRNA-ribosyltransferase)|interpro:IPR004803(Queuine tRNA-ribosyltransferase)|interpro:IPR036511|rcsb pdb:6H42|rcsb pdb:6H45|reactome:R-HSA-6782315|go:"GO:0046872"(metal ion binding) - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:0Z1Trg9nHJebKDjnOB6gBKvoMxA9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q9BST9 intact:EBI-26375106 intact:EBI-446694|uniprotkb:Q8WVN1|uniprotkb:Q96PT6|uniprotkb:Q9HB05|uniprotkb:H7BXD4|intact:EBI-28972758|ensembl:ENSP00000272430 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rtkn_human(display_long)|uniprotkb:RTKN1(gene name synonym)|uniprotkb:RTKN(gene name)|psi-mi:RTKN(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001015055.1|refseq:NP_001015056.1|refseq:NP_149035.1|ensembl:ENST00000233330|ensembl:ENSP00000233330|ensembl:ENSP00000272430|ensembl:ENST00000305557|ensembl:ENSP00000305298|refseq:XP_016860124.1|dip:DIP-31098N|ensembl:ENSG00000114993(gene)|ensembl:ENST00000272430(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012966(Protein of unknown function DUF1709, fungi)|interpro:IPR030471|mint:Q9BST9|reactome:R-HSA-5666185|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:Bep3YojtNr0rbW7zImG6oXyrQHw9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q96RS0 intact:EBI-26375106 intact:EBI-949244|ensembl:ENSP00000260129|uniprotkb:A6NJQ5|uniprotkb:Q5GH23|uniprotkb:Q8TDG9|uniprotkb:Q96QU3|uniprotkb:Q9H5V3|intact:EBI-2563555 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:tgs1_human(display_long)|uniprotkb:Cap-specific guanine-N2 methyltransferase(gene name synonym)|uniprotkb:Nuclear receptor coactivator 6-interacting protein(gene name synonym)|uniprotkb:PRIP-interacting protein with methyltransferase motif(gene name synonym)|uniprotkb:CLL-associated antigen KW-2(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 137(gene name synonym)|uniprotkb:TGS1(gene name)|psi-mi:TGS1(display_short)|uniprotkb:PIMT(gene name synonym)|uniprotkb:HCA137(gene name synonym)|uniprotkb:NCOA6IP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000137574(gene)|ensembl:ENST00000260129(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0009452"(7-methylguanosine RNA capping)|go:"GO:0015030"(Cajal body)|go:"GO:0022613"(ribonucleoprotein complex biogenesis)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0036261"(7-methylguanosine cap hypermethylation)|go:"GO:0071164"(RNA trimethylguanosine synthase activity)|interpro:IPR019012|interpro:IPR029063|rcsb pdb:3EGI|rcsb pdb:3GDH|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-191859|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:NP_079107.6|refseq:NP_001304831.1|dip:DIP-49970N - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:K72Uc4b54997Kq/gZWB5NMPfLVk9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q96KR1 intact:EBI-26375106 intact:EBI-2513582|ensembl:ENSP00000265069|uniprotkb:Q9Y687|uniprotkb:Q6P5A3|uniprotkb:B2RNR5|uniprotkb:Q9H6V4|uniprotkb:Q3B7X5|uniprotkb:Q05C08|uniprotkb:Q9NTI1|uniprotkb:Q86UA0|intact:EBI-2560216 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:zfr_human(display_long)|uniprotkb:ZFR(gene name)|psi-mi:ZFR(display_short)|uniprotkb:M-phase phosphoprotein homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000056097(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|mint:Q96KR1|ensembl:ENST00000265069(transcript)|refseq:NP_057191.2|ensembl:ENSP00000265069|dip:DIP-47293N - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:UQQP+tkUcQYka9ez6rMv2F6FXFM9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q96EL2 intact:EBI-26375106 intact:EBI-1055789|uniprotkb:P82668|uniprotkb:Q96Q23|uniprotkb:Q9P047|uniprotkb:A4D1U9|ensembl:ENSP00000318158 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt24_human(display_long)|uniprotkb:bMRP-47(gene name synonym)|uniprotkb:MRPS24(gene name)|psi-mi:MRPS24(display_short)|uniprotkb:HSPC335(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS3m(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_114403.1|ensembl:ENSG00000062582(gene)|ensembl:ENST00000317534(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR026146|mint:Q96EL2|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:OEtFmhoLM1Sw9YVrL88HZQ5Ju0g9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q92552 intact:EBI-26375106 intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q8N567 intact:EBI-26375106 intact:EBI-5235536|uniprotkb:B2RAE7|uniprotkb:Q9H027|ensembl:ENSP00000254037|ensembl:ENSP00000369546|ensembl:ENSP00000385047|ensembl:ENSP00000412637 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:zchc9_human(display_long)|uniprotkb:ZCCHC9(gene name)|psi-mi:ZCCHC9(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001124507.1|refseq:NP_001124508.1|refseq:NP_115656.1|ensembl:ENSG00000131732(gene)|ensembl:ENST00000254037(transcript)|ensembl:ENST00000380199(transcript)|ensembl:ENST00000407610(transcript)|ensembl:ENST00000438268(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR042246 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:M/NIA60lFfPQAjGBMtHILP1zw/s9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q8IZ69 intact:EBI-26375106 intact:EBI-2515774|uniprotkb:Q9H732|uniprotkb:Q32P57|uniprotkb:Q96ME6|uniprotkb:D3DX25|ensembl:ENSP00000252136|ensembl:ENSP00000385807 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:trm2a_human(display_long)|uniprotkb:TRMT2A(gene name)|psi-mi:TRMT2A(display_short)|uniprotkb:HTF9C(gene name synonym)|uniprotkb:HpaII tiny fragments locus 9c protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_073564.3|refseq:NP_892029.2|refseq:NP_001244923.1|ensembl:ENSP00000252136|ensembl:ENSP00000385807|ensembl:ENST00000404751|ensembl:ENSP00000384968|ensembl:ENSG00000099899(gene)|ensembl:ENST00000252136(transcript)|ensembl:ENST00000403707(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010280("(Uracil-5)-methyltransferase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029063|interpro:IPR034262|interpro:IPR035979|mint:Q8IZ69 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:/G2YDfinTNhJ+mPHfHOwSsyHQxE9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q8IY37 intact:EBI-26375106 intact:EBI-308285|uniprotkb:Q9BUI7|uniprotkb:Q9P211|ensembl:ENSP00000311135 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:dhx37_human(display_long)|uniprotkb:DHX37(gene name)|psi-mi:DHX37(display_short)|uniprotkb:DDX37(gene name synonym)|uniprotkb:KIAA1517(gene name synonym)|uniprotkb:DEAH box protein 37(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_116045.2|ensembl:ENSG00000150990(gene)|ensembl:ENST00000308736(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007420"(brain development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042255"(ribosome assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q8IY37|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:y+2TFmurlGgCJ2pjTjfAttqC3xE9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q86W50 intact:EBI-26375106 intact:EBI-5461849|uniprotkb:D3DTI8|uniprotkb:Q86TE5|uniprotkb:Q96T16|uniprotkb:Q9BVG7|ensembl:ENSP00000263092 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:met16_human(display_long)|uniprotkb:Methyltransferase-like protein 16(gene name synonym)|uniprotkb:N6-adenosine-methyltransferase METTL16(gene name synonym)|uniprotkb:METTL16(gene name)|psi-mi:METTL16(display_short)|uniprotkb:METT10D(gene name synonym)|uniprotkb:Methyltransferase 10 domain-containing protein(gene name synonym)|uniprotkb:"U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_076991.3|ensembl:ENSG00000127804(gene)|ensembl:ENST00000263092(transcript)|go:"GO:0001734"("mRNA (N6-adenosine)-methyltransferase activity")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0052907"("23S rRNA (adenine(1618)-N(6))-methyltransferase activity")|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070475"(rRNA base methylation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0120048"("U6 snRNA (adenine-(43)-N(6))-methyltransferase activity")|go:"GO:0120049"("snRNA (adenine-N6)-methylation")|go:"GO:1905869"(negative regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR010286(S-adenosyl-L-methionine dependent methyltransferase, predicted)|interpro:IPR017182(S-adenosyl-L-methionine dependent methyltransferase, Mett10D, predicted)|interpro:IPR029063|rcsb pdb:2H00|rcsb pdb:6B91|rcsb pdb:6B92|rcsb pdb:6DU4|rcsb pdb:6DU5|rcsb pdb:6GFK|rcsb pdb:6GFN|rcsb pdb:6GT5|rcsb pdb:6M1U - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:52jq3dlPCmoMJ8y8lBiP3tdtdMw9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q7L2J0 intact:EBI-26375106 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q7KZI7 intact:EBI-26375106 intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|dip:DIP-31321N|ensembl:ENSG00000072518(gene)|ensembl:ENST00000402010(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001764"(neuron migration)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q6DD87 intact:EBI-26375106 intact:EBI-5457592|uniprotkb:A0A087WUD1|uniprotkb:O00455|ensembl:ENSP00000478557 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:zn787_human(display_long)|uniprotkb:ZNF787(gene name)|psi-mi:ZNF787(display_short)|uniprotkb:TTF-I-interacting peptide 20(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001002836.2|refseq:XP_011524747.1|ensembl:ENSG00000142409(gene)|ensembl:ENST00000610935(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6DD87 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:B25i4bTxTWsGThUtdlCr4DnweoE9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q68D10 intact:EBI-26375106 intact:EBI-11035441|uniprotkb:Q8N8I3|uniprotkb:Q8N3E7|uniprotkb:Q6MZI5|uniprotkb:Q86VG8|uniprotkb:Q7Z390|uniprotkb:Q6AWA5|uniprotkb:Q8N417|uniprotkb:Q7Z470|ensembl:ENSP00000337991 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:spt2_human(display_long)|uniprotkb:SPTY2D1(gene name)|psi-mi:SPTY2D1(display_short)|uniprotkb:Protein KU002155(gene name synonym)|uniprotkb:SPT2 domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_919261.2|ensembl:ENSG00000179119(gene)|ensembl:ENST00000336349(transcript)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010847"(regulation of chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|interpro:IPR013256(Chromatin SPT2)|rcsb pdb:5BS7|rcsb pdb:5BSA - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:HCyEUXPH2GeH6wURfB8Hq72F2+w9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q5VYS8 intact:EBI-26375106 intact:EBI-2810086|uniprotkb:Q96N57|uniprotkb:Q658Z9|uniprotkb:Q8N5F0|uniprotkb:Q96NE8|uniprotkb:Q5H9T0|uniprotkb:Q9C0F2|uniprotkb:Q6MZJ3|uniprotkb:Q659A2|uniprotkb:Q5VYS5|uniprotkb:Q9H8M6|uniprotkb:Q5VYS7|ensembl:ENSP00000365130 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:tut7_human(display_long)|uniprotkb:TUT7(gene name)|psi-mi:TUT7(display_short)|uniprotkb:HS2(gene name synonym)|uniprotkb:KIAA1711(gene name synonym)|uniprotkb:ZCCHC6(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 6(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001171988.1|refseq:NP_001172003.1|refseq:NP_078893.2|ensembl:ENST00000375963(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0070569"(uridylyltransferase activity)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:1990074"(polyuridylation-dependent mRNA catabolic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036875|interpro:IPR043519|rcsb pdb:5W0B|rcsb pdb:5W0M|rcsb pdb:5W0N|rcsb pdb:5W0O|reactome:R-HSA-429947|ensembl:ENSG00000083223(gene)|refseq:NP_001317647.1|refseq:XP_016870619.1|refseq:XP_016870620.1 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:7SZLc/DgsdZVQBnq8x5e2MCunyQ9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q5VV52 intact:EBI-26375106 intact:EBI-720883|ensembl:ENSP00000361580|ensembl:ENSP00000498913|uniprotkb:O95878|uniprotkb:Q9NWE8|uniprotkb:A8MXP6|uniprotkb:B4DJR7 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:zn691_human(display_long)|uniprotkb:ZNF691(gene name)|psi-mi:ZNF691(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) ensembl:ENSG00000164011(gene)|ensembl:ENST00000372502(transcript)|ensembl:ENST00000651192(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001229668.1|refseq:NP_056995.1|refseq:XP_016856889.1|refseq:XP_016856890.1 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:EZAAGPZ/5Plp6lhQqW3omkLo+CE9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q4G0J3 intact:EBI-26375106 intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-2560173|ensembl:ENSP00000314311|ensembl:ENSP00000344950|ensembl:ENSP00000499190 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_056269.1|refseq:NP_057732.2|refseq:NP_001253968.1|dip:DIP-47624N|ensembl:ENSG00000174720(gene)|ensembl:ENST00000324052(transcript)|ensembl:ENST00000344442(transcript)|ensembl:ENST00000651579(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q49MG5 intact:EBI-26375106 intact:EBI-11331350|uniprotkb:Q9H7B6|uniprotkb:Q4W5I7|uniprotkb:Q9H781|uniprotkb:Q68DU1|ensembl:ENSP00000310593|ensembl:ENSP00000498412 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:map9_human(display_long)|uniprotkb:MAP9(gene name)|psi-mi:MAP9(display_short)|uniprotkb:ASAP(gene name synonym)|uniprotkb:Aster-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001034669.1|refseq:XP_011530555.1|refseq:XP_011530556.1|ensembl:ENSG00000164114(gene)|ensembl:ENST00000311277(transcript)|ensembl:ENST00000650955(transcript)|go:"GO:0000235"(astral microtubule)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0051233"(spindle midzone)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902412"(regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026106 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:1Qfouz+ujVvGh/zuF8+1GJCcrvo9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q15434 intact:EBI-26375106 intact:EBI-721278|ensembl:ENSP00000262031 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rbms2_human(display_long)|uniprotkb:Suppressor of CDC2 with RNA-binding motif 3(gene name synonym)|uniprotkb:RBMS2(gene name)|psi-mi:RBMS2(display_short)|uniprotkb:SCR3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_002889.1|refseq:XP_011536942.1|refseq:XP_006719607.1|go:"GO:0005634"(nucleus)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|ensembl:ENSG00000076067(gene)|ensembl:ENST00000262031(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:1X4E - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:Xp/0q4sekgC32j5HNpSoZZq/Idg9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:Q02040 intact:EBI-26375106 intact:EBI-1042725|uniprotkb:Q02832|uniprotkb:Q2TB98|uniprotkb:Q5JQ74|uniprotkb:Q5JQ76|uniprotkb:Q8N6U9|ensembl:ENSP00000324827 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:ak17a_human(display_long)|uniprotkb:AKAP17A(gene name)|psi-mi:AKAP17A(display_short)|uniprotkb:DXYS155E(gene name synonym)|uniprotkb:Protein XE7(gene name synonym)|uniprotkb:B-lymphocyte antigen(gene name synonym)|uniprotkb:721P(gene name synonym)|uniprotkb:SFRS17A(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 17A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 17A(gene name synonym)|uniprotkb:CXYorf3(gene name synonym)|uniprotkb:XE7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_005079.2|ensembl:ENSG00000197976(gene)|ensembl:ENST00000313871(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042113"(B cell activation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR034355|interpro:IPR035979 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:Od9lQN7lrCl0uP/r3m6iX4vtCfg9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P82675 intact:EBI-26375106 intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS5m(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_114108.1|ensembl:ENSG00000144029(gene)|ensembl:ENST00000272418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6RW5|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P82663 intact:EBI-26375106 intact:EBI-1046734|uniprotkb:Q9H7P5|ensembl:ENSP00000253686|uniprotkb:B4DFJ5|uniprotkb:B4DQG6 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt25_human(display_long)|uniprotkb:MRPS25(gene name)|psi-mi:MRPS25(display_short)|uniprotkb:RPMS25(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS25(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_071942.1|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000131368(gene)|ensembl:ENST00000253686(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR040049|mint:P82663|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:DQMtBaQJW2Ic025zsKJYfN4aj1I9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P61011 intact:EBI-26375106 intact:EBI-2854176|uniprotkb:B2R759|uniprotkb:P13624|uniprotkb:B4DUW6|ensembl:ENSP00000216774|ensembl:ENSP00000451818|ensembl:ENSP00000504518|ensembl:ENSP00000504673 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:srp54_human(display_long)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:XP_011535408.1|refseq:NP_001139754.1|refseq:NP_003127.1|ensembl:ENSG00000100883(gene)|ensembl:ENST00000678963(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019003"(GDP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|mint:P61011|rcsb pdb:1MFQ|rcsb pdb:1QB2|rcsb pdb:5L3Q|rcsb pdb:6Y2Z|rcsb pdb:6Y30|rcsb pdb:6Y31|rcsb pdb:6Y32|rcsb pdb:7NFX|ensembl:ENST00000216774(transcript)|reactome:R-HSA-1799339|ensembl:ENST00000556994(transcript)|ensembl:ENST00000677647(transcript) - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:8iRlU+NvhLEJNv7B90TAZyRqwiY9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P51398 intact:EBI-26375106 intact:EBI-355912|uniprotkb:Q13044|uniprotkb:Q96Q20|uniprotkb:Q68CT7|uniprotkb:B4DP59|uniprotkb:E7EM60|uniprotkb:B4DY62|ensembl:ENSP00000341692|ensembl:ENSP00000357320 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:rt29_human(display_long)|uniprotkb:DAP3(gene name)|psi-mi:DAP3(display_short)|uniprotkb:MRPS29(gene name synonym)|uniprotkb:Death-associated protein 3(gene name synonym)|uniprotkb:Ionizing radiation resistance conferring protein(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS29(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001186778.1|refseq:NP_004623.1|refseq:NP_387506.1|refseq:NP_001186779.1|refseq:NP_001186780.1|refseq:XP_005245537.1|refseq:XP_005245538.1|ensembl:ENSG00000132676(gene)|ensembl:ENST00000343043(transcript)|ensembl:ENST00000368336(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR008092(Death associated protein 3)|interpro:IPR019368|interpro:IPR027417|mint:P51398|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_016857780.1|refseq:XP_016857781.1|refseq:XP_016857782.1 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:xSIyqKH4F49Iu+AVuVThJWsi9EA9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P49189 intact:EBI-26375106 intact:EBI-1055313|uniprotkb:B2R6X1|uniprotkb:Q6LCL1|uniprotkb:Q9NZT7|uniprotkb:Q5VV90|uniprotkb:B4DXY7|uniprotkb:B9EKV4 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:al9a1_human(display_long)|uniprotkb:Aldehyde dehydrogenase family 9 member A1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase E3 isozyme(gene name synonym)|uniprotkb:Gamma-aminobutyraldehyde dehydrogenase(gene name synonym)|uniprotkb:R-aminobutyraldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH9A1(gene name)|psi-mi:ALDH9A1(display_short)|uniprotkb:ALDH7(gene name synonym)|uniprotkb:ALDH9(gene name synonym)|uniprotkb:ALDH4(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_000687.3|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|refseq:XP_011507596.1|interpro:IPR029510|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0019145"(aminobutyraldehyde dehydrogenase activity)|go:"GO:0033737"(1-pyrroline dehydrogenase activity)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0047105"(4-trimethylammoniobutyraldehyde dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:6QAK|rcsb pdb:6QAO|rcsb pdb:6QAP|rcsb pdb:6VR6|rcsb pdb:6VWF|reactome:R-HSA-71262|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:P49189 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:MYde00UETppWGSEKa35Jsck7Joc9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P38935 intact:EBI-26375106 intact:EBI-372250|uniprotkb:Q00443|uniprotkb:Q14177|uniprotkb:A0PJD2|ensembl:ENSP00000255078 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:smbp2_human(display_long)|uniprotkb:IGHMBP2(gene name)|psi-mi:IGHMBP2(display_short)|uniprotkb:SMBP2(gene name synonym)|uniprotkb:SMUBP2(gene name synonym)|uniprotkb:ATP-dependent helicase IGHMBP2(gene name synonym)|uniprotkb:Immunoglobulin mu-binding protein 2(gene name synonym)|uniprotkb:Glial factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_002171.2|ensembl:ENSG00000132740(gene)|ensembl:ENST00000255078(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006412"(translation)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000058(Zinc finger, AN1-type)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004483(DNA helicase, putative)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR034072|interpro:IPR035896|interpro:IPR036867|interpro:IPR041677|interpro:IPR041679|rcsb pdb:1MSZ|rcsb pdb:2LRR|rcsb pdb:4B3F|rcsb pdb:4B3G - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:AE7bXQuPHW5lmbRyohcOEOkMp+g9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:P09132 intact:EBI-26375106 intact:EBI-2680090|uniprotkb:B2R4E9|uniprotkb:Q96FG6|uniprotkb:Q05D77|uniprotkb:D6RCQ5|ensembl:ENSP00000424870 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:srp19_human(display_long)|uniprotkb:SRP19(gene name)|psi-mi:SRP19(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_001191123.1|refseq:NP_003126.1|refseq:NP_001191122.1|refseq:NP_001191125.1|ensembl:ENSG00000153037(gene)|ensembl:ENST00000505459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR036521|mint:P09132|rcsb pdb:1JID|rcsb pdb:1MFQ|rcsb pdb:1RY1|rcsb pdb:2J37|rcsb pdb:3KTV|rcsb pdb:4P3E|rcsb pdb:5M73|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-41412N - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:yIFmf1q6m2wQt3eaiCc1dlIQXn89606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:O76094 intact:EBI-26375106 intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:O75569 intact:EBI-26375106 intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:tZfziopZlC+1d3De97G3kDY+Tog9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:O00566 intact:EBI-26375106 intact:EBI-5235884|uniprotkb:A0AVJ8|ensembl:ENSP00000244230 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:mpp10_human(display_long)|uniprotkb:MPHOSPH10(gene name)|psi-mi:MPHOSPH10(display_short)|uniprotkb:MPP10(gene name synonym)|uniprotkb:M phase phosphoprotein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_005782.1|ensembl:ENSG00000124383(gene)|ensembl:ENST00000244230(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR012173(U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p)|mint:O00566|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:xkz11U1x5r2joVtVq6JG4asO1Qw9606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N4V0 uniprotkb:O43818 intact:EBI-26375106 intact:EBI-2115327|uniprotkb:Q8IZ30|uniprotkb:B2R996|ensembl:ENSP00000232888 psi-mi:orf4a_mers1(display_long)|uniprotkb:ORF4a(gene name)|psi-mi:ORF4a(display_short) psi-mi:u3ip2_human(display_long)|uniprotkb:RRP9(gene name)|psi-mi:RRP9(display_short)|uniprotkb:RNU3IP2(gene name synonym)|uniprotkb:U355K(gene name synonym)|uniprotkb:U3 small nucleolar ribonucleoprotein-associated 55 kDa protein(gene name synonym)|uniprotkb:RRP9 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375098|imex:IM-28441-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint) refseq:NP_004695.1|ensembl:ENSG00000114767(gene)|ensembl:ENST00000232888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR039241|rcsb pdb:4J0W|rcsb pdb:4JXM|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:V3VCHTQdW5QZGaVa3wVENn1TyBQ1263720 rogid:AxnPDovGXO2JPghV7c6ztiV1/z89606 rigid:ovMPOsubTeGPyQsf0FYGQjtx5us false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:Q9Y2E5 intact:EBI-25641007 intact:EBI-12243024|ensembl:ENSP00000285599|uniprotkb:Q66MP2|uniprotkb:Q86T67 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:ma2b2_human(display_long)|uniprotkb:MAN2B2(gene name)|psi-mi:MAN2B2(display_short)|uniprotkb:KIAA0935(gene name synonym)|uniprotkb:Mannosidase alpha class 2B member 2(gene name synonym)|uniprotkb:Alpha-1,6-mannosidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 interpro:IPR028995|interpro:IPR037094|interpro:IPR041147|reactome:R-HSA-8853383|ensembl:ENSG00000013288(gene)|ensembl:ENST00000285599(transcript)|go:"GO:0004559"(alpha-mannosidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000602(Glycoside hydrolase, family 38, core)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR011330(Glycoside hydrolase/deacetylase, beta/alpha-barrel)|interpro:IPR011682(Glycosyl hydrolases 38, C-terminal)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR015341(Glycoside hydrolase, family 38, central region)|interpro:IPR027291|refseq:NP_001278967.1|refseq:NP_056089.1 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:Rb9bwbALmqM3goVDHEEHegV3R649606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:Q9UKX7 intact:EBI-25641007 intact:EBI-2371082|uniprotkb:O75644|uniprotkb:Q9NPM9|uniprotkb:Q9NPR6|uniprotkb:Q9P1K5|uniprotkb:B2RB15|uniprotkb:B1AHA4|uniprotkb:Q8N6V5|ensembl:ENSP00000345895 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:nup50_human(display_long)|uniprotkb:NUP50(gene name)|psi-mi:NUP50(display_short)|uniprotkb:NPAP60L(gene name synonym)|uniprotkb:Nuclear pore-associated protein 60 kDa-like(gene name synonym)|uniprotkb:PRO1146(orf name)|uniprotkb:Nucleoporin Nup50(gene name synonym)|uniprotkb:50 kDa nucleoporin(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 refseq:XP_011528135.1|refseq:NP_009103.2|refseq:NP_705931.1|refseq:XP_006724166.1|refseq:XP_006724167.1|refseq:XP_005261369.1|refseq:XP_005261371.1|refseq:XP_016884026.1|ensembl:ENSG00000093000(gene)|ensembl:ENST00000347635(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|mint:Q9UKX7|rcsb pdb:2EC1|rcsb pdb:3TJ3|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:tg/qpkdGAm/M6vLvvCzdTCZoxiA9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:Q93009 intact:EBI-25641007 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:Q07021 intact:EBI-25641007 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:P52294 intact:EBI-25641007 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:P52292 intact:EBI-25641007 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:P49790 intact:EBI-25641007 intact:EBI-286779|uniprotkb:Q5T9I7|intact:EBI-1237421|uniprotkb:E7EPX5|uniprotkb:Q4LE47|uniprotkb:Q7Z743|uniprotkb:B4DIK2|uniprotkb:F6QR24|ensembl:ENSP00000262077 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:nu153_human(display_long)|uniprotkb:Nucleoporin Nup153(gene name synonym)|uniprotkb:153 kDa nucleoporin(gene name synonym)|uniprotkb:NUP153(gene name)|psi-mi:NUP153(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 ensembl:ENSP00000262077|ensembl:ENST00000537253|ensembl:ENSP00000444029|ensembl:ENST00000613258|ensembl:ENSP00000478627|refseq:NP_005115.2|refseq:NP_001265138.1|refseq:NP_001265139.1|dip:DIP-38185N|ensembl:ENSG00000124789(gene)|ensembl:ENST00000262077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043657"(host cell)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046832"(negative regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013913(Nucleoporin, Nup153-like)|interpro:IPR018892|interpro:IPR026054|interpro:IPR036443|mint:P49790|rcsb pdb:2EBQ|rcsb pdb:2EBR|rcsb pdb:2EBV|rcsb pdb:2GQE|rcsb pdb:4U0C|rcsb pdb:4U0D|rcsb pdb:5TSV|rcsb pdb:5TSX|rcsb pdb:6AYA|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:rOax/ikcAu5fmDiCOauVr7Y/fzY9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:O60930 intact:EBI-25641007 intact:EBI-2372399|uniprotkb:O60523|uniprotkb:O60857|uniprotkb:Q57Z93|uniprotkb:Q5U0C1|uniprotkb:Q6FHD4|uniprotkb:B3KQU4|ensembl:ENSP00000313350 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:rnh1_human(display_long)|uniprotkb:RNASEH1(gene name)|psi-mi:RNASEH1(display_short)|uniprotkb:RNH1(gene name synonym)|uniprotkb:Ribonuclease H type II(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 refseq:NP_002927.2|ensembl:ENSG00000171865(gene)|ensembl:ENST00000315212(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR011320(Ribonuclease HI, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017067(Ribonuclease H1, eukaryote)|interpro:IPR036397|interpro:IPR037056|mint:O60930|rcsb pdb:2QK9|rcsb pdb:2QKB|rcsb pdb:2QKK|rcsb pdb:3BSU|rcsb pdb:6VRD - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:5ewRaIy98nsi0xPoW4OxG0dTHYU9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:O60684 intact:EBI-25641007 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:O15131 intact:EBI-25641007 intact:EBI-540602|uniprotkb:Q86X23|uniprotkb:B2RAI5|ensembl:ENSP00000348704|ensembl:ENSP00000357552 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:ima6_human(display_long)|uniprotkb:Karyopherin subunit alpha-5(gene name synonym)|uniprotkb:KPNA5(gene name)|psi-mi:KPNA5(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 refseq:NP_002260.2|reactome:R-HSA-1169408|reactome:R-HSA-168276|rcsb pdb:4U2X|ensembl:ENSG00000196911(gene)|ensembl:ENST00000356348(transcript)|ensembl:ENST00000368564(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O15131|refseq:XP_016866328.1|refseq:XP_016866329.1|dip:DIP-33405N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:ixGSmHZKndxkY0NFF1Adu+7SmEA9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:O00505 intact:EBI-25641007 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N643 uniprotkb:O00629 intact:EBI-25641007 intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:orf4b_mers1(display_long)|uniprotkb:ORF4b(gene name)|psi-mi:ORF4b(display_short) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375164|imex:IM-28441-141 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|interpro:IPR044321 refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:UigjTsSxDYztzrnbYDtfQ/dupSE1263720 rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 rigid:XDPLBPnUT/HKNze8GML+rS2f3oA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7D2 uniprotkb:Q96S66 intact:EBI-26375191 intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|ensembl:ENSP00000349456|ensembl:ENSP00000358986|ensembl:ENSP00000502251|ensembl:ENSP00000502457|ensembl:ENSP00000502648|ensembl:ENSP00000502836 psi-mi:orf5_mers1(display_long)|uniprotkb:ORF5(gene name)|psi-mi:ORF5(display_short) psi-mi:clcc1_human(display_long)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375184|imex:IM-28441-107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR044323 refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940(gene)|ensembl:ENST00000356970(transcript)|ensembl:ENST00000369969(transcript)|ensembl:ENST00000674849(transcript)|ensembl:ENST00000675508(transcript)|ensembl:ENST00000675654(transcript)|ensembl:ENST00000675956(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR009231(Mid-1-related chloride channel) - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:NYjno+XosmhMJFEtP7rkKiCSZqs1263720 rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606 rigid:wFDMuxntmwu0SeOqBEDId+jTFYA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7D2 uniprotkb:P81408 intact:EBI-26375191 intact:EBI-6366314|uniprotkb:Q8IXL3|uniprotkb:Q9BR66|uniprotkb:B1AVS5|ensembl:ENSP00000354958|ensembl:ENSP00000461152 psi-mi:orf5_mers1(display_long)|uniprotkb:ORF5(gene name)|psi-mi:ORF5(display_short) psi-mi:f189b_human(display_long)|uniprotkb:FAM189B(gene name)|psi-mi:FAM189B(display_short)|uniprotkb:C1orf2(gene name synonym)|uniprotkb:COTE1(gene name synonym)|uniprotkb:Protein COTE1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375184|imex:IM-28441-107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR044323 ensembl:ENST00000350210|ensembl:ENSP00000307128|ensembl:ENSP00000354958|ensembl:ENST00000368368|ensembl:ENSP00000357352|ensembl:ENST00000572488|ensembl:ENSP00000458501|ensembl:ENST00000574749|ensembl:ENSP00000460960|ensembl:ENSP00000461152|refseq:NP_006580.2|refseq:NP_937995.1|refseq:XP_005244902.1|refseq:NP_001254537.1|ensembl:ENSG00000160767(gene)|ensembl:ENSG00000262666(gene)|ensembl:ENST00000361361(transcript)|ensembl:ENST00000575430(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050699"(WW domain binding)|interpro:IPR007237(CD20/IgE Fc receptor beta subunit)|interpro:IPR030431 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:NYjno+XosmhMJFEtP7rkKiCSZqs1263720 rogid:OqQAQJyKeRWNRHJWSpZMgZR/Vmk9606 rigid:wFDMuxntmwu0SeOqBEDId+jTFYA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7D2 uniprotkb:P46379 intact:EBI-26375191 intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894 psi-mi:orf5_mers1(display_long)|uniprotkb:ORF5(gene name)|psi-mi:ORF5(display_short) psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375184|imex:IM-28441-107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR044323 dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:NYjno+XosmhMJFEtP7rkKiCSZqs1263720 rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606 rigid:wFDMuxntmwu0SeOqBEDId+jTFYA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7D2 uniprotkb:P11441 intact:EBI-26375191 intact:EBI-356983|uniprotkb:Q5HY80|ensembl:ENSP00000358674 psi-mi:orf5_mers1(display_long)|uniprotkb:ORF5(gene name)|psi-mi:ORF5(display_short) psi-mi:ubl4a_human(display_long)|uniprotkb:UBL4A(gene name)|psi-mi:UBL4A(display_short)|uniprotkb:GDX(gene name synonym)|uniprotkb:DXS254E(gene name synonym)|uniprotkb:UBL4(gene name synonym)|uniprotkb:Ubiquitin-like protein GDX(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375184|imex:IM-28441-107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR044323 refseq:NP_055050.1|ensembl:ENSG00000102178(gene)|ensembl:ENST00000369660(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016020"(membrane)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR041421|interpro:IPR044724|mint:P11441|rcsb pdb:2DZI|rcsb pdb:4WWR|rcsb pdb:4X86|reactome:R-HSA-9609523 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:NYjno+XosmhMJFEtP7rkKiCSZqs1263720 rogid:euKOrDRC1mx0s2QVY95010PRaIg9606 rigid:wFDMuxntmwu0SeOqBEDId+jTFYA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:K9N7D2 uniprotkb:P02786 intact:EBI-26375191 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 psi-mi:orf5_mers1(display_long)|uniprotkb:ORF5(gene name)|psi-mi:ORF5(display_short) psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:1263720(cvemc)|taxid:1263720("Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (Betacoronavirus England 1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375184|imex:IM-28441-107 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0044177"(host cell Golgi apparatus)|interpro:IPR044323 refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/19 rogid:NYjno+XosmhMJFEtP7rkKiCSZqs1263720 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 rigid:wFDMuxntmwu0SeOqBEDId+jTFYA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC4 uniprotkb:Q8IWA5 intact:EBI-25475850 intact:EBI-11722896|uniprotkb:B2RBB1|uniprotkb:B3KNH3|uniprotkb:B4DFJ0|uniprotkb:F2Q9D7|uniprotkb:Q658V1|uniprotkb:Q658Z2|uniprotkb:Q6PJV7|uniprotkb:Q8N2F0|uniprotkb:Q9NY68|ensembl:ENSP00000336888 psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name) psi-mi:ctl2_human(display_long)|uniprotkb:SLC44A2(gene name)|psi-mi:SLC44A2(display_short)|uniprotkb:CTL2(gene name synonym)|uniprotkb:Solute carrier family 44 member 2(gene name synonym)|uniprotkb:PSEC0210(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375224|imex:IM-28441-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001138528.1|refseq:NP_065161.3|refseq:XP_005260054.1|ensembl:ENSG00000129353(gene)|ensembl:ENST00000335757(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007603(Protein of unknown function DUF580)|mint:Q8IWA5|reactome:R-HSA-1483191|reactome:R-HSA-425366|reactome:R-HSA-6798695 - - - figure legend:Table 2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049 rogid:SSl8Mo7YUgoqMyEdqv9w02Qj0iM9606 rigid:wsvraudBtRhWhECpuBR500ULNOY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC4 uniprotkb:Q86VM9 intact:EBI-25475850 intact:EBI-1045965|uniprotkb:Q96DG4|uniprotkb:Q96MP7|ensembl:ENSP00000301011 psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name) psi-mi:zch18_human(display_long)|uniprotkb:NHN1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym)|uniprotkb:ZC3H18(gene name)|psi-mi:ZC3H18(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375224|imex:IM-28441-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001281269.1|ensembl:ENST00000301011(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|mint:Q86VM9|ensembl:ENSG00000158545(gene)|ensembl:ENSP00000301011|refseq:NP_653205.3 - - - figure legend:Table 2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049 rogid:H9lST8OLyCpyi5AWYqFYskL0ezI9606 rigid:wsvraudBtRhWhECpuBR500ULNOY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC4 uniprotkb:Q6UX04 intact:EBI-25475850 intact:EBI-2214108|uniprotkb:O60529|uniprotkb:O60530|uniprotkb:Q96EM3|ensembl:ENSP00000370460 psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name) psi-mi:cwc27_human(display_long)|uniprotkb:SDCCAG10(gene name synonym)|uniprotkb:CWC27(gene name)|psi-mi:CWC27(display_short)|uniprotkb:Serologically defined colon cancer antigen 10(gene name synonym)|uniprotkb:Antigen NY-CO-10(gene name synonym)|uniprotkb:UNQ438/PRO871(orf name)|uniprotkb:Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375224|imex:IM-28441-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001284573.1|refseq:NP_001284574.1|refseq:NP_005860.2|ensembl:ENSG00000153015(gene)|ensembl:ENST00000381070(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|interpro:IPR044666|rcsb pdb:2HQ6|rcsb pdb:4R3E|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6YVH|rcsb pdb:7DVQ|reactome:R-HSA-72163 - - - figure legend:Table 2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049 rogid:4FP6Whtw50x+g8DoR0ocAjEaQmk9606 rigid:wsvraudBtRhWhECpuBR500ULNOY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC4 uniprotkb:P25440 intact:EBI-25475850 intact:EBI-2874802|uniprotkb:Q5STC9|uniprotkb:Q6P3U2|uniprotkb:O00699|uniprotkb:B1AZT1|uniprotkb:B0S7P0|uniprotkb:Q969U4|uniprotkb:Q15310|uniprotkb:O00700|uniprotkb:A2AAU0|uniprotkb:Q63HQ9|uniprotkb:Q658Y7|ensembl:ENSP00000363958|ensembl:ENSP00000363964|ensembl:ENSP00000372588|ensembl:ENSP00000382444|ensembl:ENSP00000382445|ensembl:ENSP00000391246|ensembl:ENSP00000399009|ensembl:ENSP00000401791|ensembl:ENSP00000409145|ensembl:ENSP00000449380|ensembl:ENSP00000449609|ensembl:ENSP00000502900 psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name) psi-mi:brd2_human(display_long)|uniprotkb:BRD2(gene name)|psi-mi:BRD2(display_short)|uniprotkb:KIAA9001(gene name synonym)|uniprotkb:RING3(gene name synonym)|uniprotkb:O27.1.1(gene name synonym)|uniprotkb:Really interesting new gene 3 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375224|imex:IM-28441-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001278915.1|refseq:NP_001106653.1|refseq:NP_001186384.1|refseq:NP_001186385.1|refseq:NP_005095.1|dip:DIP-60835N|ensembl:ENSG00000204256(gene)|ensembl:ENSG00000215077(gene)|ensembl:ENSG00000234507(gene)|ensembl:ENSG00000234704(gene)|ensembl:ENSG00000235307(gene)|ensembl:ENST00000374825(transcript)|ensembl:ENST00000374831(transcript)|ensembl:ENST00000383108(transcript)|ensembl:ENST00000399528(transcript)|ensembl:ENST00000399529(transcript)|ensembl:ENST00000414731(transcript)|ensembl:ENST00000438194(transcript)|ensembl:ENST00000449085(transcript)|ensembl:ENST00000449118(transcript)|ensembl:ENST00000549126(transcript)|ensembl:ENST00000552587(transcript)|ensembl:ENST00000678250(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:P25440|rcsb pdb:1X0J|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2DVS|rcsb pdb:2DVV|rcsb pdb:2E3K|rcsb pdb:2G4A|rcsb pdb:2YDW|rcsb pdb:2YEK|rcsb pdb:3AQA|rcsb pdb:3ONI|rcsb pdb:4A9E|rcsb pdb:4A9F|rcsb pdb:4A9H|rcsb pdb:4A9I|rcsb pdb:4A9J|rcsb pdb:4A9M|rcsb pdb:4A9N|rcsb pdb:4A9O|rcsb pdb:4AKN|rcsb pdb:4ALG|rcsb pdb:4ALH|rcsb pdb:4J1P|rcsb pdb:4MR5|rcsb pdb:4QEU|rcsb pdb:4QEV|rcsb pdb:4QEW|rcsb pdb:4UYF|rcsb pdb:4UYG|rcsb pdb:4UYH|rcsb pdb:5BT5|rcsb pdb:5DFB|rcsb pdb:5DFC|rcsb pdb:5DFD|rcsb pdb:5DW1|rcsb pdb:5EK9|rcsb pdb:5HEL|rcsb pdb:5HEM|rcsb pdb:5HEN|rcsb pdb:5HFQ|rcsb pdb:5IBN|rcsb pdb:5IG6|rcsb pdb:5N2L|rcsb pdb:5O38|rcsb pdb:5O39|rcsb pdb:5O3A|rcsb pdb:5O3B|rcsb pdb:5O3C|rcsb pdb:5O3D|rcsb pdb:5O3E|rcsb pdb:5O3F|rcsb pdb:5O3G|rcsb pdb:5O3H|rcsb pdb:5O3I|rcsb pdb:5U5S|rcsb pdb:5U6V|rcsb pdb:5UEW|rcsb pdb:5XHE|rcsb pdb:5XHK|rcsb pdb:6CUI|rcsb pdb:6DB0|rcsb pdb:6DBC|rcsb pdb:6DDI|rcsb pdb:6DDJ|rcsb pdb:4MR6|rcsb pdb:6E6J|rcsb pdb:6FFE|rcsb pdb:6FFF|rcsb pdb:6FFG|rcsb pdb:6I80|rcsb pdb:6I81|rcsb pdb:6JKE|rcsb pdb:6K05|rcsb pdb:6MO7|rcsb pdb:6MO8|rcsb pdb:6MO9|rcsb pdb:6MOA|rcsb pdb:6ONY|rcsb pdb:6SWO|rcsb pdb:6SWP|rcsb pdb:6TQ1|rcsb pdb:6TQ2|rcsb pdb:6U61|rcsb pdb:6U71|rcsb pdb:6U8H|rcsb pdb:6ULQ|rcsb pdb:6ULT|rcsb pdb:6VIY|rcsb pdb:6YTM|rcsb pdb:6Z7F|rcsb pdb:6Z8P|rcsb pdb:6ZB0|rcsb pdb:6ZB1|rcsb pdb:6ZB2|rcsb pdb:7JX7|rcsb pdb:7L6D|rcsb pdb:7NQ5|rcsb pdb:7NQ7|rcsb pdb:7NQ8|rcsb pdb:7NQ9|rcsb pdb:7NQI|rcsb pdb:7NQJ|reactome:R-HSA-8951936|rcsb pdb:6K04 - - - figure legend:Table 2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049 rogid:Q3ELpiTZgboufxPDV/bypJZC2oY9606 rigid:wsvraudBtRhWhECpuBR500ULNOY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC4 uniprotkb:O60885 intact:EBI-25475850 intact:EBI-723869|uniprotkb:O60433|uniprotkb:Q86YS8|uniprotkb:Q96PD3|intact:EBI-28968271|ensembl:ENSP00000263377|ensembl:ENSP00000506350|uniprotkb:Q4G0X8 psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name) psi-mi:brd4_human(display_long)|uniprotkb:Protein HUNK1(gene name synonym)|uniprotkb:BRD4(gene name)|psi-mi:BRD4(display_short)|uniprotkb:HUNK1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375224|imex:IM-28441-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_055114.1|refseq:NP_490597.1|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000141867(gene)|ensembl:ENST00000263377(transcript)|ensembl:ENST00000679869(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:O60885|rcsb pdb:2I8N|rcsb pdb:2LSP|rcsb pdb:2MJV|rcsb pdb:2N3K|rcsb pdb:2NCZ|rcsb pdb:2ND0|rcsb pdb:2ND1|rcsb pdb:2NNU|rcsb pdb:2OSS|rcsb pdb:2OUO|rcsb pdb:2YEL|rcsb pdb:2YEM|rcsb pdb:3MXF|rcsb pdb:5Y93|rcsb pdb:5Y94|rcsb pdb:5YOU|rcsb pdb:5YOV|rcsb pdb:5YQX|rcsb pdb:5Z1R|rcsb pdb:5Z1S|rcsb pdb:5Z1T|rcsb pdb:5Z5T|rcsb pdb:5Z5U|rcsb pdb:5Z5V|rcsb pdb:5Z8G|rcsb pdb:5Z8R|rcsb pdb:5Z8Z|rcsb pdb:5Z90|rcsb pdb:5Z9C|rcsb pdb:5Z9K|rcsb pdb:6AFR|rcsb pdb:6AJV|rcsb pdb:6AJW|rcsb pdb:6AJX|rcsb pdb:6AJY|rcsb pdb:6AJZ|rcsb pdb:6BN7|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BNH|rcsb pdb:6BOY|rcsb pdb:6C7Q|rcsb pdb:6C7R|rcsb pdb:6CD4|rcsb pdb:6CD5|rcsb pdb:6CIS|rcsb pdb:6CIY|rcsb pdb:6CJ1|rcsb pdb:6CJ2|rcsb pdb:6CKR|rcsb pdb:6CKS|rcsb pdb:6CZU|rcsb pdb:6CZV|rcsb pdb:6DJC|rcsb pdb:6DL2|rcsb pdb:6DMJ|rcsb pdb:6DML|rcsb pdb:6DNE|rcsb pdb:6DUV|rcsb pdb:6FFD|rcsb pdb:6FNX|rcsb pdb:6FO5|rcsb pdb:6E4A|rcsb pdb:6FSY|rcsb pdb:6FT3|rcsb pdb:6FT4|rcsb pdb:6G0D|rcsb pdb:6G0E|rcsb pdb:6G0F|rcsb pdb:6G0G|rcsb pdb:6G0H|rcsb pdb:6G0O|rcsb pdb:6G0P|rcsb pdb:6G0Q|rcsb pdb:6G0R|rcsb pdb:6G0S|rcsb pdb:6HDQ|rcsb pdb:6HOV|rcsb pdb:6I7X|rcsb pdb:6I7Y|rcsb pdb:6IN1|rcsb pdb:6JI3|rcsb pdb:6JI4|rcsb pdb:6JI5|rcsb pdb:6JJ3|rcsb pdb:6JJ5|rcsb pdb:6JJ6|rcsb pdb:6JJB|rcsb pdb:6KEC|rcsb pdb:6KED|rcsb pdb:6KEE|rcsb pdb:6KEF|rcsb pdb:6KEG|rcsb pdb:6KEH|rcsb pdb:6KEI|rcsb pdb:6KEJ|rcsb pdb:6KEK|rcsb pdb:6KO2|rcsb pdb:6SB8|rcsb pdb:6SE4|rcsb pdb:6SIS|rcsb pdb:6LG4|rcsb pdb:6SWN|rcsb pdb:6SWQ|rcsb pdb:6TPX|rcsb pdb:6TPY|rcsb pdb:6TPZ|rcsb pdb:6U0D|rcsb pdb:6U6K|rcsb pdb:6U6L|rcsb pdb:6U72|rcsb pdb:6U74|rcsb pdb:6U8G|rcsb pdb:6U8I|rcsb pdb:6U8M|rcsb pdb:6ULS|rcsb pdb:6ULV|rcsb pdb:6UVJ|rcsb pdb:6UVM|rcsb pdb:6UWU|rcsb pdb:6UWX|rcsb pdb:6V0U|rcsb pdb:6V1K|rcsb pdb:6V1L|rcsb pdb:6V1U|rcsb pdb:3SVF|rcsb pdb:3SVG|rcsb pdb:3U5J|rcsb pdb:3U5K|rcsb pdb:3U5L|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3ZYU|rcsb pdb:4A9L|rcsb pdb:4BJX|rcsb pdb:4BW1|rcsb pdb:4BW2|rcsb pdb:4BW3|rcsb pdb:4BW4|rcsb pdb:4C66|rcsb pdb:4C67|rcsb pdb:3P5O|rcsb pdb:4CFK|rcsb pdb:4CFL|rcsb pdb:4CL9|rcsb pdb:6LG6|rcsb pdb:6LG7|rcsb pdb:6LG8|rcsb pdb:6LG9|rcsb pdb:6LIH|rcsb pdb:6LIM|rcsb pdb:6MAU|rcsb pdb:6MH1|rcsb pdb:6MH7|rcsb pdb:6MNL|rcsb pdb:6P05|rcsb pdb:6PRT|rcsb pdb:6PS9|rcsb pdb:6PSB|rcsb pdb:6Q3Y|rcsb pdb:6LG5|rcsb pdb:6Q3Z|rcsb pdb:6RWJ|rcsb pdb:6S25|rcsb pdb:6S4B|rcsb pdb:6S6K|rcsb pdb:6SA2|rcsb pdb:6SA3|rcsb pdb:6SAH|rcsb pdb:6SAJ|rcsb pdb:4DON|rcsb pdb:4E96|rcsb pdb:4F3I|rcsb pdb:4GPJ|rcsb pdb:4HBV|rcsb pdb:4HBW|rcsb pdb:4HBX|rcsb pdb:4HBY|rcsb pdb:4HXK|rcsb pdb:4HXL|rcsb pdb:4HXM|rcsb pdb:4HXN|rcsb pdb:4HXO|rcsb pdb:4HXP|rcsb pdb:4HXR|rcsb pdb:4HXS|rcsb pdb:4IOO|rcsb pdb:4IOQ|rcsb pdb:4IOR|rcsb pdb:4J0R|rcsb pdb:4J0S|rcsb pdb:4J3I|rcsb pdb:4CLB|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:4LR6|rcsb pdb:4LRG|rcsb pdb:4LYI|rcsb pdb:4LYS|rcsb pdb:4LYW|rcsb pdb:4LZR|rcsb pdb:4LZS|rcsb pdb:4MEN|rcsb pdb:4MEO|rcsb pdb:4MEP|rcsb pdb:4MEQ|rcsb pdb:4MR3|rcsb pdb:4MR4|rcsb pdb:4NQM|rcsb pdb:4NR8|rcsb pdb:4NUC|rcsb pdb:4NUD|rcsb pdb:4NUE|rcsb pdb:4O70|rcsb pdb:4O71|rcsb pdb:4O72|rcsb pdb:4O74|rcsb pdb:4O75|rcsb pdb:4O76|rcsb pdb:4O77|rcsb pdb:4O78|rcsb pdb:4O7A|rcsb pdb:4O7B|rcsb pdb:4O7C|rcsb pdb:4O7E|rcsb pdb:4O7F|rcsb pdb:4OGI|rcsb pdb:4OGJ|rcsb pdb:4PCE|rcsb pdb:4PCI|rcsb pdb:4PS5|rcsb pdb:4QR3|rcsb pdb:4QR4|rcsb pdb:4QR5|rcsb pdb:4QZS|rcsb pdb:4UIX|rcsb pdb:4UIY|rcsb pdb:4UIZ|rcsb pdb:4UYD|rcsb pdb:4WHW|rcsb pdb:4WIV|rcsb pdb:4X2I|rcsb pdb:4XY9|rcsb pdb:4XYA|rcsb pdb:4YH3|rcsb pdb:4YH4|rcsb pdb:4Z1Q|rcsb pdb:4QB3|rcsb pdb:4Z1S|rcsb pdb:4Z93|rcsb pdb:4ZC9|rcsb pdb:4ZW1|rcsb pdb:5ACY|rcsb pdb:5AD2|rcsb pdb:5AD3|rcsb pdb:5BT4|rcsb pdb:5CFW|rcsb pdb:5COI|rcsb pdb:5CP5|rcsb pdb:5CPE|rcsb pdb:5CQT|rcsb pdb:5A5S|rcsb pdb:5CRM|rcsb pdb:5CRZ|rcsb pdb:5CS8|rcsb pdb:5CTL|rcsb pdb:5CY9|rcsb pdb:5D0C|rcsb pdb:5D24|rcsb pdb:5D25|rcsb pdb:5D26|rcsb pdb:5D3H|rcsb pdb:5D3J|rcsb pdb:5D3L|rcsb pdb:5D3N|rcsb pdb:5D3P|rcsb pdb:5A85|rcsb pdb:5D3R|rcsb pdb:5D3S|rcsb pdb:5D3T|rcsb pdb:5DLX|rcsb pdb:5DLZ|rcsb pdb:5DX4|rcsb pdb:5E0R|rcsb pdb:5EGU|rcsb pdb:5EI4|rcsb pdb:5EIS|rcsb pdb:5F5Z|rcsb pdb:5F60|rcsb pdb:5F61|rcsb pdb:5F62|rcsb pdb:5F63|rcsb pdb:5FBX|rcsb pdb:5H21|rcsb pdb:5HCL|rcsb pdb:5HLS|rcsb pdb:5HM0|rcsb pdb:5HQ5|rcsb pdb:5HQ6|rcsb pdb:5HQ7|rcsb pdb:5I80|rcsb pdb:5I88|rcsb pdb:5IGK|rcsb pdb:5JWM|rcsb pdb:5KDH|rcsb pdb:5KHM|rcsb pdb:5KJ0|rcsb pdb:5KU3|rcsb pdb:5LJ1|rcsb pdb:5LJ2|rcsb pdb:5LRQ|rcsb pdb:5LUU|rcsb pdb:5M39|rcsb pdb:5M3A|rcsb pdb:5MKZ|rcsb pdb:5DW2|rcsb pdb:5MLI|rcsb pdb:5N2M|rcsb pdb:5NNC|rcsb pdb:5NND|rcsb pdb:5NNE|rcsb pdb:5NNF|rcsb pdb:5NNG|rcsb pdb:5O97|rcsb pdb:5UES|rcsb pdb:5UET|rcsb pdb:5OVB|rcsb pdb:5OWM|rcsb pdb:5UEU|rcsb pdb:5UEV|rcsb pdb:5UEX|rcsb pdb:5UEY|rcsb pdb:5UEZ|rcsb pdb:5OWW|rcsb pdb:5UF0|rcsb pdb:5ULA|rcsb pdb:5UOO|rcsb pdb:5UVS|rcsb pdb:5UVT|rcsb pdb:5UVU|rcsb pdb:5UVV|rcsb pdb:5UVW|rcsb pdb:5T35|rcsb pdb:5TI2|rcsb pdb:5TI3|rcsb pdb:5TI4|rcsb pdb:5TI5|rcsb pdb:5TI6|rcsb pdb:5TI7|rcsb pdb:5U28|rcsb pdb:5U2C|rcsb pdb:5U2E|rcsb pdb:5U2F|rcsb pdb:5UVX|rcsb pdb:5UVY|rcsb pdb:5UVZ|rcsb pdb:5V67|rcsb pdb:5VBO|rcsb pdb:5VBP|rcsb pdb:5UEO|rcsb pdb:5VOM|rcsb pdb:5VZS|rcsb pdb:5W55|rcsb pdb:5WA5|rcsb pdb:5WMA|rcsb pdb:5WMD|rcsb pdb:5WMG|rcsb pdb:5WUU|rcsb pdb:5UEP|rcsb pdb:5XHY|rcsb pdb:5UEQ|rcsb pdb:5XI2|rcsb pdb:5XI3|rcsb pdb:5UER|rcsb pdb:5XI4|rcsb pdb:5Y1Y|rcsb pdb:5Y8C|rcsb pdb:5Y8W|rcsb pdb:5Y8Y|rcsb pdb:5Y8Z|rcsb pdb:6VIW|rcsb pdb:6VIX|rcsb pdb:6VIZ|ensembl:ENSP00000263377|ensembl:ENST00000360016|ensembl:ENSP00000353112|ensembl:ENST00000371835|ensembl:ENSP00000360901|ensembl:ENSP00000506350|rcsb pdb:7A9U|rcsb pdb:7AJN|rcsb pdb:7C2Z|rcsb pdb:7C6P|rcsb pdb:7JKX|rcsb pdb:7KHH|rcsb pdb:7KHL|rcsb pdb:7MCF|reactome:R-HSA-9679191|rcsb pdb:6ZF9|rcsb pdb:6VUC|rcsb pdb:6VUF|rcsb pdb:6VUJ|rcsb pdb:6WGX|rcsb pdb:6WW8|rcsb pdb:6X7B|rcsb pdb:6X7C|rcsb pdb:6X7D|rcsb pdb:6XUZ|rcsb pdb:6XV3|rcsb pdb:6XV7|rcsb pdb:6XVC|rcsb pdb:6YIN|rcsb pdb:6YQN|rcsb pdb:6YQO|rcsb pdb:6YQP|rcsb pdb:6YQZ|rcsb pdb:6Z7G|rcsb pdb:6Z7L|rcsb pdb:6Z7M|rcsb pdb:6ZB3|rcsb pdb:6ZCI|rcsb pdb:6ZED|rcsb pdb:6ZEL|rcsb pdb:6VUB|refseq:NP_001317313.1|refseq:XP_011526156.1|refseq:XP_011526158.1|dip:DIP-39776N - - - figure legend:Table 2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049 rogid:tzQWCG/IwJWaOJ7XO+pXHkPVg+w9606 rigid:wsvraudBtRhWhECpuBR500ULNOY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC4 uniprotkb:O00203 intact:EBI-25475850 intact:EBI-1044383|ensembl:ENSP00000255194|uniprotkb:O00580|uniprotkb:Q7Z393|uniprotkb:Q9HD66|uniprotkb:E5RJ68|intact:EBI-10969499 psi-mi:vemp_sars2(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:4(orf name) psi-mi:ap3b1_human(display_long)|uniprotkb:Adaptor protein complex AP-3 subunit beta-1(gene name synonym)|uniprotkb:Beta-3A-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-1 large chain(gene name synonym)|uniprotkb:AP3B1(gene name)|psi-mi:AP3B1(display_short)|uniprotkb:ADTB3A(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375224|imex:IM-28441-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7M4R|rcsb pdb:7NTK|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724392.1|interpro:IPR043506|interpro:IPR044377|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|rcsb pdb:7K3G|reactome:R-HSA-9694322|reactome:R-HSA-9694493|reactome:R-HSA-9694614|reactome:R-HSA-9694635 go:"GO:0006464"(cellular protein modification process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007040"(lysosome organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016020"(membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032438"(melanosome organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0090152"(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:"GO:0098773"(skin epidermis development)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|interpro:IPR029394|mint:O00203|reactome:R-HSA-432722|reactome:R-HSA-6802952|refseq:NP_003655.3|ensembl:ENSG00000132842(gene)|ensembl:ENST00000255194(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003016"(respiratory system process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|refseq:NP_001258698.1|dip:DIP-24208N - - - figure legend:Table 2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:UWky5j9vE+Fp5EQSeWzUPWq6Ghc2697049 rogid:+06UuQo62p9ALS7DiX+yKg7YRyg9606 rigid:wsvraudBtRhWhECpuBR500ULNOY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9Y6E2 intact:EBI-25475853 intact:EBI-1051021|uniprotkb:Q3B779|uniprotkb:Q9H3F7|uniprotkb:A4D123|uniprotkb:Q96JW5|ensembl:ENSP00000258761|ensembl:ENSP00000397249 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:bzw2_human(display_long)|uniprotkb:BZW2(gene name)|psi-mi:BZW2(display_short)|uniprotkb:HSPC028(orf name)|uniprotkb:MSTP017(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001153239.1|refseq:NP_054757.1|ensembl:ENSG00000136261(gene)|ensembl:ENST00000258761(transcript)|ensembl:ENST00000433922(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|refseq:XP_006715769.1|refseq:XP_006715770.1|refseq:XP_006715771.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:+z22Ykb6e3IM9zk51m6tjuhiEcU9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9Y312 intact:EBI-25475853 intact:EBI-748721|uniprotkb:Q9H4F9|uniprotkb:Q9P1P3|uniprotkb:Q9UFK9|uniprotkb:E1P5S7|ensembl:ENSP00000313674|ensembl:ENSP00000363043|ensembl:ENSP00000505061|ensembl:ENSP00000505295|ensembl:ENSP00000505405|ensembl:ENSP00000506185|ensembl:ENSP00000506354 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:aar2_human(display_long)|uniprotkb:AAR2(gene name)|psi-mi:AAR2(display_short)|uniprotkb:AAR2 splicing factor homolog(gene name synonym)|uniprotkb:C20orf4(gene name synonym)|uniprotkb:CGI-23(orf name)|uniprotkb:PRO0225(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_056326.2|refseq:NP_001258803.1|refseq:XP_006723833.1|refseq:XP_011527065.1|refseq:XP_011527064.1|ensembl:ENSG00000131043(gene)|ensembl:ENST00000320849(transcript)|ensembl:ENST00000373932(transcript)|ensembl:ENST00000679667(transcript)|ensembl:ENST00000680247(transcript)|ensembl:ENST00000680639(transcript)|ensembl:ENST00000680811(transcript)|ensembl:ENST00000680933(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|interpro:IPR007946(AAR2)|interpro:IPR033647|interpro:IPR033648|interpro:IPR038514|interpro:IPR038516|mint:Q9Y312 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:mvbhGa01cuYd3fN8vbbXdzS0mSg9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9ULX6 intact:EBI-25475853 intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9UDR5 intact:EBI-25475853 intact:EBI-1237169|uniprotkb:O95462|ensembl:ENSP00000377040|ensembl:ENSP00000403768|ensembl:ENSP00000505381|ensembl:ENSP00000505958 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:aass_human(display_long)|uniprotkb:AASS(gene name)|psi-mi:AASS(display_short)|uniprotkb:LKR/SDH(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_005754.2|ensembl:ENSG00000008311(gene)|ensembl:ENST00000393376(transcript)|ensembl:ENST00000417368(transcript)|ensembl:ENST00000679511(transcript)|ensembl:ENST00000679864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004753"(saccharopine dehydrogenase activity)|go:"GO:0004754"("saccharopine dehydrogenase (NAD+, L-lysine-forming) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006554"(lysine catabolic process)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047130"("saccharopine dehydrogenase (NADP+, L-lysine-forming) activity")|go:"GO:0047131"("saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity")|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR032095|interpro:IPR036291|rcsb pdb:5L76|rcsb pdb:5L78|rcsb pdb:5O1N|rcsb pdb:5O1O|rcsb pdb:5O1P|reactome:R-HSA-71064 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:UKSIs4pNgKcCqgLa0h1pDf1znnQ9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9UBU6 intact:EBI-25475853 intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:0HV6qye10bMGdnt9CiGztIacrHM9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9NQC3 intact:EBI-25475853 intact:EBI-715945|intact:EBI-1753019|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y2Y7|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|ensembl:ENSP00000337838|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 ensembl:ENST00000317610|ensembl:ENSP00000322147|ensembl:ENSP00000337838|ensembl:ENST00000357376|ensembl:ENSP00000349944|ensembl:ENST00000357732|ensembl:ENSP00000350365|ensembl:ENST00000394609|ensembl:ENSP00000378107|ensembl:ENST00000394611|ensembl:ENSP00000378109|ensembl:ENST00000404909|ensembl:ENSP00000385650|ensembl:ENST00000405240|ensembl:ENSP00000384471|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|ensembl:ENSG00000115310(gene)|ensembl:ENST00000337526(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:XP_005264491.1|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9BW92 intact:EBI-25475853 intact:EBI-1045099|uniprotkb:Q53GW7|uniprotkb:Q96I50|ensembl:ENSP00000358060|uniprotkb:Q9H9V2 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:sytm_human(display_long)|uniprotkb:Threonyl-tRNA synthetase-like 1(gene name synonym)|uniprotkb:TARS2(gene name)|psi-mi:TARS2(display_short)|uniprotkb:TARSL1(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_079426.2|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR004095(TGS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018163|interpro:IPR033728|interpro:IPR036621|reactome:R-HSA-379726|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|ensembl:ENSG00000143374(gene)|ensembl:ENST00000369064(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004829"(threonine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006435"(threonyl-tRNA aminoacylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070159"(mitochondrial threonyl-tRNA aminoacylation)|refseq:NP_001258825.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:9osvUit1PmESv7edUxgA1cl3o/Y9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9BSJ2 intact:EBI-25475853 intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q9BQT8 intact:EBI-25475853 intact:EBI-6268670|ensembl:ENSP00000329452|uniprotkb:A8K0L0|uniprotkb:G3V4L5|uniprotkb:Q3MJ99 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:odc_human(display_long)|uniprotkb:SLC25A21(gene name)|psi-mi:SLC25A21(display_short)|uniprotkb:ODC(gene name synonym)|uniprotkb:Solute carrier family 25 member 21(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 ensembl:ENSG00000183032(gene)|ensembl:ENST00000331299(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006554"(lysine catabolic process)|go:"GO:0015139"(alpha-ketoglutarate transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1990550"(mitochondrial alpha-ketoglutarate transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-HSA-71064|refseq:NP_001164641.1|refseq:NP_085134.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:vjU+HXQnFdVrJ80S6EAyBasaypc9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q96HW7 intact:EBI-25475853 intact:EBI-5663129|uniprotkb:Q96GA1|uniprotkb:Q9BRC0|uniprotkb:Q6PJG4|uniprotkb:Q96G32|uniprotkb:Q2YD62|uniprotkb:Q7Z4E7|ensembl:ENSP00000434466 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:int4_human(display_long)|uniprotkb:MSTP093(orf name)|uniprotkb:INTS4(gene name)|psi-mi:INTS4(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_291025.3|ensembl:ENSG00000149262(gene)|ensembl:ENST00000534064(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026003|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:uGlRFHMzcYz15rtJ/XSGqTaNSPA9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q96HR9 intact:EBI-25475853 intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q96ER3 intact:EBI-25475853 intact:EBI-721193|uniprotkb:A6NH05|ensembl:ENSP00000432487 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:saal1_human(display_long)|uniprotkb:Synoviocyte proliferation-associated in collagen-induced arthritis protein 1(gene name synonym)|uniprotkb:SAAL1(gene name)|psi-mi:SAAL1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_612430.2|ensembl:ENSG00000166788(gene)|ensembl:ENST00000524803(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:1901647"(positive regulation of synoviocyte proliferation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:/zDVy3k3FVjctiLf1XeIeWHL9BE9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q96D53 intact:EBI-25475853 intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q96CW5 intact:EBI-25475853 intact:EBI-1046278|ensembl:ENSP00000261965|uniprotkb:O43631|uniprotkb:O60852|uniprotkb:O60853|uniprotkb:Q7Z4K1|uniprotkb:Q96I79|uniprotkb:Q5T8L2 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:gcp3_human(display_long)|uniprotkb:Spindle pole body protein Spc98 homolog(gene name synonym)|uniprotkb:TUBGCP3(gene name)|psi-mi:TUBGCP3(display_short)|uniprotkb:GCP3(gene name synonym)|uniprotkb:Gamma-ring complex protein 104 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007338"(single fertilization)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q96CW5|rcsb pdb:6V6B|go:"GO:0000930"(gamma-tubulin complex)|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|ensembl:ENSG00000126216(gene)|ensembl:ENST00000261965(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000923"(equatorial microtubule organizing center)|refseq:NP_006313.1|refseq:NP_001273207.1|refseq:NP_001273208.1|refseq:NP_001273206.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:xt+Ngo2s/4djh2PnyMEaxgDyLrs9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q8NEW0 intact:EBI-25475853 intact:EBI-1043569|uniprotkb:Q8TCH2|ensembl:ENSP00000350278|ensembl:ENSP00000359130|uniprotkb:B2R949|uniprotkb:D3DT61 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:znt7_human(display_long)|uniprotkb:SLC30A7(gene name)|psi-mi:SLC30A7(display_short)|uniprotkb:ZNT7(gene name synonym)|uniprotkb:ZNTL2(gene name synonym)|uniprotkb:Znt-like transporter 2(gene name synonym)|uniprotkb:Solute carrier family 30 member 7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 ensembl:ENSG00000162695(gene)|ensembl:ENST00000357650(transcript)|ensembl:ENST00000370112(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006829"(zinc ion transport)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|reactome:R-HSA-264876|reactome:R-HSA-435368|go:"GO:0032119"(sequestering of zinc ion)|refseq:NP_001138356.1|refseq:NP_598003.2|refseq:XP_016855889.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:/okPwOjluCDoM8a5uHoixAyRc8E9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q7L8L6 intact:EBI-25475853 intact:EBI-747570|uniprotkb:Q96JN3|uniprotkb:Q9H5D1|uniprotkb:Q9H8Y3|ensembl:ENSP00000369618 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:fakd5_human(display_long)|uniprotkb:FASTKD5(gene name)|psi-mi:FASTKD5(display_short)|uniprotkb:KIAA1792(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_068598.1|ensembl:ENSG00000215251(gene)|ensembl:ENST00000380266(transcript)|go:"GO:0000963"(mitochondrial RNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:i48wNX7cmBCPpWXkXfnZhGnrse89606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q6PML9 intact:EBI-25475853 intact:EBI-2818242|uniprotkb:Q8TBB2|uniprotkb:Q7Z5I7|uniprotkb:Q4W5B6|uniprotkb:Q9Y6R2|ensembl:ENSP00000264451 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:znt9_human(display_long)|uniprotkb:SLC30A9(gene name)|psi-mi:SLC30A9(display_short)|uniprotkb:C4orf1(gene name synonym)|uniprotkb:HUEL(gene name synonym)|uniprotkb:Human embryonic lung protein(gene name synonym)|uniprotkb:Solute carrier family 30 member 9(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_006336.3|ensembl:ENSG00000014824(gene)|ensembl:ENST00000264451(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0005634"(nucleus)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR002524(Cation efflux protein)|interpro:IPR009061(Putative DNA binding)|interpro:IPR027469|interpro:IPR037129|interpro:IPR040177|rcsb pdb:2ENK - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:FOpcvusmMSLnk+espRUTV4ijPoQ9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q5JRX3 intact:EBI-25475853 intact:EBI-2432778|uniprotkb:B4E0J8|uniprotkb:E7ES23|uniprotkb:B3KMJ6|uniprotkb:O95204|uniprotkb:Q2M2G6|uniprotkb:Q4VBR1|uniprotkb:Q5JRW7|uniprotkb:Q7L5Z7|uniprotkb:Q9BSI6|uniprotkb:Q9BVJ5|uniprotkb:Q9UPP8|uniprotkb:C9JSL2|ensembl:ENSP00000224949 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:prep_human(display_long)|uniprotkb:PITRM1(gene name)|psi-mi:PITRM1(display_short)|uniprotkb:KIAA1104(gene name synonym)|uniprotkb:MP1(gene name synonym)|uniprotkb:Pitrilysin metalloproteinase 1(gene name synonym)|uniprotkb:PREP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001229236.1|refseq:NP_001229238.1|refseq:NP_055704.2|dip:DIP-52900N|ensembl:ENSG00000107959(gene)|ensembl:ENST00000224949(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006508"(proteolysis)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR013578(Peptidase M16C associated)|mint:Q5JRX3|rcsb pdb:4L3T|rcsb pdb:4NGE|rcsb pdb:4RPU|reactome:R-HSA-1268020 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:1kEY/XJB5fwgNRoM9u9ZGT+VrS09606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q4KMQ2 intact:EBI-25475853 intact:EBI-2820640|ensembl:ENSP00000320087|ensembl:ENSP00000506222|uniprotkb:E9PB30|uniprotkb:E9PCT2|uniprotkb:A6NNM6|uniprotkb:Q8N3Q2|uniprotkb:B9EGG0|uniprotkb:E7ENK4 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:ano6_human(display_long)|uniprotkb:ANO6(gene name)|psi-mi:ANO6(display_short)|uniprotkb:TMEM16F(gene name synonym)|uniprotkb:Transmembrane protein 16F(gene name synonym)|uniprotkb:Small-conductance calcium-activated nonselective cation channel(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032060"(bleb assembly)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035590"(purinergic nucleotide receptor signaling pathway)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0046872"(metal ion binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0061589"(calcium activated phosphatidylserine scrambling)|go:"GO:0006948"(induction by virus of host cell-cell fusion)|ensembl:ENST00000320560(transcript)|ensembl:ENST00000680201(transcript)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002543"(activation of blood coagulation via clotting cascade)|go:"GO:0005227"(calcium activated cation channel activity)|go:"GO:0005229"(intracellular calcium activated chloride channel activity)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006821"(chloride transport)|ensembl:ENSG00000177119(gene)|go:"GO:0061590"(calcium activated phosphatidylcholine scrambling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0097045"(phosphatidylserine exposure on blood platelet)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1903766"(positive regulation of potassium ion export across plasma membrane)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR007632(Protein of unknown function DUF590)|interpro:IPR031295|interpro:IPR032394|reactome:R-HSA-2672351|reactome:R-HSA-6798695|refseq:NP_001020527.2|refseq:NP_001136150.1|refseq:NP_001136151.1|refseq:NP_001191732.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:3cDBZkwscaW9OTGlqzj0M7pcBhg9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q10713 intact:EBI-25475853 intact:EBI-2514696|ensembl:ENSP00000360782|uniprotkb:Q8N513|uniprotkb:Q16639|uniprotkb:Q5SXM9|uniprotkb:B4DKL3|uniprotkb:E7ET61 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:mppa_human(display_long)|uniprotkb:PMPCA(gene name)|psi-mi:PMPCA(display_short)|uniprotkb:INPP5E(gene name synonym)|uniprotkb:KIAA0123(gene name synonym)|uniprotkb:MPPA(gene name synonym)|uniprotkb:Alpha-MPP(gene name synonym)|uniprotkb:P-55(gene name synonym)|uniprotkb:Inactive zinc metalloprotease alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001269875.1|ensembl:ENSG00000165688(gene)|ensembl:ENST00000371717(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-HSA-1268020|reactome:R-HSA-8949664|interpro:IPR037715|refseq:NP_001269873.1|refseq:NP_055975.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:Kqz7qIyX2eUOcnNrfIsSPjc4Isw9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:Q00765 intact:EBI-25475853 intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:P48556 intact:EBI-25475853 intact:EBI-359304|uniprotkb:Q6P1L7|uniprotkb:B4DX18|ensembl:ENSP00000215071|ensembl:ENSP00000481136 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:psmd8_human(display_long)|uniprotkb:PSMD8(gene name)|psi-mi:PSMD8(display_short)|uniprotkb:26S proteasome regulatory subunit S14(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN12(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_002803.2|ensembl:ENSG00000099341(gene)|ensembl:ENST00000215071(transcript)|ensembl:ENST00000620216(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|mint:P48556|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5M32|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-180534 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:73qmlkzCwdeHlNzUy7vy7qmIok09606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:P38606 intact:EBI-25475853 intact:EBI-1054757|intact:EBI-10982175|uniprotkb:Q53YD9|uniprotkb:Q96DY6|uniprotkb:Q9UHY3|uniprotkb:B2RBR8|uniprotkb:B7Z1R5|uniprotkb:D3DN75|ensembl:ENSP00000273398 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:vata_human(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Vacuolar ATPase isoform VA68(gene name synonym)|uniprotkb:ATP6V1A(gene name)|psi-mi:ATP6V1A(display_short)|uniprotkb:ATP6A1(gene name synonym)|uniprotkb:ATP6V1A1(gene name synonym)|uniprotkb:VPP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_001681.2|ensembl:ENSG00000114573(gene)|ensembl:ENST00000273398(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P38606|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:GqPRFwsl5tDH83kpE8Al7NiYWrI9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:P38435 intact:EBI-25475853 intact:EBI-10963113|ensembl:ENSP00000233838|uniprotkb:B4DMC5|uniprotkb:E9PEE1|uniprotkb:Q6GU45|uniprotkb:Q14415 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:vkgc_human(display_long)|uniprotkb:GGCX(gene name)|psi-mi:GGCX(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:Gamma-glutamyl carboxylase(gene name synonym)|uniprotkb:Peptidyl-glutamate 4-carboxylase(gene name synonym)|uniprotkb:Vitamin K gamma glutamyl carboxylase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_000812.2|refseq:NP_001135741.1|ensembl:ENSG00000115486(gene)|ensembl:ENST00000233838(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007596"(blood coagulation)|go:"GO:0008488"(gamma-glutamyl carboxylase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0019842"(vitamin binding)|interpro:IPR007782(Vitamin K-dependent gamma-carboxylase)|interpro:IPR011020(HTTM)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|mint:P38435|reactome:R-HSA-159740|reactome:R-HSA-9673240 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:icDLv1KyH9HC3h9enCp9S/nXPmM9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:P27105 intact:EBI-25475853 intact:EBI-1211440|uniprotkb:Q14087|uniprotkb:Q15609|uniprotkb:Q5VX96|uniprotkb:Q96FK4|uniprotkb:B1AM77|ensembl:ENSP00000286713 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:stom_human(display_long)|uniprotkb:STOM(gene name)|psi-mi:STOM(display_short)|uniprotkb:BND7(gene name synonym)|uniprotkb:EPB72(gene name synonym)|uniprotkb:Protein 7.2b(gene name synonym)|uniprotkb:Erythrocyte band 7 integral membrane protein(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 7.2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_004090.4|refseq:NP_937837.1|ensembl:ENSG00000148175(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|ensembl:ENST00000286713(transcript)|go:"GO:0016020"(membrane)|go:"GO:0031982"(vesicle)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0072562"(blood microparticle)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901585"(regulation of acid-sensing ion channel activity)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR018080|interpro:IPR028515|interpro:IPR036013|interpro:IPR043202|mint:P27105|reactome:R-HSA-2672351|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:vN/5Kc8T+vO90Hk4N3RHD/u0pWc9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:P13804 intact:EBI-25475853 intact:EBI-1052886|uniprotkb:B4DT43|uniprotkb:Q53XN3|ensembl:ENSP00000452762 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:etfa_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_000117.1|refseq:NP_001121188.1|dip:DIP-6161N|ensembl:ENSG00000140374(gene)|ensembl:ENST00000557943(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:P13804|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:J2PUTTVN+nd8eHe6TXga+37CiPw9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:P11310 intact:EBI-25475853 intact:EBI-514381|uniprotkb:Q9NYF1|uniprotkb:Q5T4U4|ensembl:ENSP00000359878 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:acadm_human(display_long)|uniprotkb:Medium chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:ACADM(gene name)|psi-mi:ACADM(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_000007.1|refseq:NP_001120800.1|dip:DIP-34281N|ensembl:ENSG00000117054(gene)|ensembl:ENST00000370841(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009409"(response to cold)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P11310|rcsb pdb:1EGC|rcsb pdb:1EGD|rcsb pdb:1EGE|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:4P13|reactome:R-HSA-1989781|reactome:R-HSA-77288|reactome:R-HSA-77346|reactome:R-HSA-77348 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:rfmTmYKNQr6R6ikvfYovZIctoz49606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:P05026 intact:EBI-25475853 intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:O95070 intact:EBI-25475853 intact:EBI-2799703|uniprotkb:Q9BVD0|uniprotkb:A6NM00|uniprotkb:Q96G83|ensembl:ENSP00000366098 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:yif1a_human(display_long)|uniprotkb:54TM(gene name synonym)|uniprotkb:HYIF1P(gene name synonym)|uniprotkb:YIF1(gene name synonym)|uniprotkb:54TMp(gene name synonym)|uniprotkb:YIP1-interacting factor homolog A(gene name synonym)|uniprotkb:YIF1A(gene name)|psi-mi:YIF1A(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_065203.2|ensembl:ENSG00000174851(gene)|ensembl:ENST00000376901(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005578(Hrf1)|mint:O95070|reactome:R-HSA-381038 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:udkO5o876pUyTxBnhOchiirpW0U9606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC5 uniprotkb:O75439 intact:EBI-25475853 intact:EBI-721199|uniprotkb:O60416|uniprotkb:Q96FV4|ensembl:ENSP00000249269 psi-mi:vme1_sars2(display_long)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:M(orf name) psi-mi:mppb_human(display_long)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:P-52(gene name synonym)|uniprotkb:PMPCB(gene name)|psi-mi:PMPCB(display_short)|uniprotkb:MPPB(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375276|imex:IM-28441-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|refseq:YP_009724393.1|interpro:IPR044361|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|reactome:R-HSA-9694322|reactome:R-HSA-9694594|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:NP_004270.2|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR037718|mint:O75439|reactome:R-HSA-1268020|reactome:R-HSA-8949664|ensembl:ENSG00000105819(gene)|ensembl:ENST00000249269(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:5I1agnvO1iTo94scBqcbLIHWdEE2697049 rogid:TMqHDYssMbBpUdw0HcGrMPaJd/89606 rigid:wW4dYkldmft/OGe+uSyI7P2mTdM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q9Y3U8 intact:EBI-25475856 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q9NW13 intact:EBI-25475856 intact:EBI-2878099|ensembl:ENSP00000223073|uniprotkb:Q96CV3|uniprotkb:A4D100|uniprotkb:Q53H65|uniprotkb:B4DU52|uniprotkb:E9PDD9 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:rbm28_human(display_long)|uniprotkb:RBM28(gene name)|psi-mi:RBM28(display_short)|uniprotkb:RNA-binding motif protein 28(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9NW13|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000106344(gene)|ensembl:ENST00000223073(transcript)|refseq:NP_001159607.1|refseq:NP_060547.2 - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:yIPQX+d5YQpq3gpdtBilOXJcUsg9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q9NR30 intact:EBI-25475856 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol) - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q9UN86 intact:EBI-25475856 intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|ensembl:ENSP00000352738|ensembl:ENSP00000379069|ensembl:ENSP00000503228|ensembl:ENSP00000503239|ensembl:ENSP00000503355|ensembl:ENSP00000503669|ensembl:ENSP00000503911|ensembl:ENSP00000503943|ensembl:ENSP00000504101|ensembl:ENSP00000504159|ensembl:ENSP00000504316|ensembl:ENSP00000504361|ensembl:ENSP00000504371|ensembl:ENSP00000504496|ensembl:ENSP00000504523|ensembl:ENSP00000504585|ensembl:ENSP00000504698|ensembl:ENSP00000503504|uniprotkb:A8K6X1 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|ensembl:ENSG00000138757(gene)|ensembl:ENST00000677620(transcript)|ensembl:ENST00000678062(transcript)|ensembl:ENST00000678100(transcript)|ensembl:ENST00000678123(transcript)|ensembl:ENST00000678265(transcript)|ensembl:ENST00000678578(transcript)|ensembl:ENST00000678798(transcript)|ensembl:ENST00000678971(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|ensembl:ENST00000359707(transcript)|ensembl:ENST00000395719(transcript)|ensembl:ENST00000676584(transcript)|ensembl:ENST00000676974(transcript)|ensembl:ENST00000677162(transcript)|ensembl:ENST00000677171(transcript)|ensembl:ENST00000677201(transcript)|ensembl:ENST00000677333(transcript)|ensembl:ENST00000677566(transcript)|ensembl:ENST00000677606(transcript)|refseq:XP_011530743.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q9HCE1 intact:EBI-25475856 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q92900 intact:EBI-25475856 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q8TAD8 intact:EBI-25475856 intact:EBI-749336|uniprotkb:Q96SP9|uniprotkb:Q9H9T7|intact:EBI-1046254|ensembl:ENSP00000296215 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:snip1_human(display_long)|uniprotkb:SNIP1(gene name)|psi-mi:SNIP1(display_short)|uniprotkb:FHA domain-containing protein SNIP1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_078976.2|ensembl:ENSG00000163877(gene)|ensembl:ENST00000296215(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-38956N|mint:Q8TAD8|rcsb pdb:5Z56|rcsb pdb:5Z57|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5Z58|rcsb pdb:6FF7|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:2UWnTY01RhPuUx3PepGug23l11U9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q8NCA5 intact:EBI-25475856 intact:EBI-1210765|uniprotkb:B2RNA2|uniprotkb:Q9Y3Y6|intact:EBI-10970131|ensembl:ENSP00000238823 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:fa98a_human(display_long)|uniprotkb:FAM98A(gene name)|psi-mi:FAM98A(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_056290.3|go:"GO:0032418"(lysosome localization)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR018797|mint:Q8NCA5|ensembl:ENSG00000119812(gene)|ensembl:ENST00000238823(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006479"(protein methylation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression) - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:MEsSX6iNk+0s/sLuUawu0GR9bW89606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q6PKG0 intact:EBI-25475856 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q13310 intact:EBI-25475856 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:Q13283 intact:EBI-25475856 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:P67870 intact:EBI-25475856 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:P19784 intact:EBI-25475856 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:P11940 intact:EBI-25475856 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC9 uniprotkb:O43818 intact:EBI-25475856 intact:EBI-2115327|uniprotkb:Q8IZ30|uniprotkb:B2R996|ensembl:ENSP00000232888 psi-mi:ncap_sars2(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:u3ip2_human(display_long)|uniprotkb:RRP9(gene name)|psi-mi:RRP9(display_short)|uniprotkb:RNU3IP2(gene name synonym)|uniprotkb:U355K(gene name synonym)|uniprotkb:U3 small nucleolar ribonucleoprotein-associated 55 kDa protein(gene name synonym)|uniprotkb:RRP9 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375317|imex:IM-28441-111 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7CR5|rcsb pdb:7LGD|rcsb pdb:7LUX|rcsb pdb:7LUZ|rcsb pdb:7LV2|rcsb pdb:7N0I|rcsb pdb:7N0R|rcsb pdb:7R98|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6M3M|rcsb pdb:6WJI|rcsb pdb:6WKP|rcsb pdb:6YI3|rcsb pdb:6YUN|rcsb pdb:7C22|refseq:YP_009724397.2|interpro:IPR043505|interpro:IPR044344|interpro:IPR044345|interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR037179|interpro:IPR037195|rcsb pdb:7DE1|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:6VYO|rcsb pdb:6WZO|rcsb pdb:6WZQ|rcsb pdb:6ZCO|rcsb pdb:7CDZ|rcsb pdb:7CE0|rcsb pdb:7ACS|rcsb pdb:7ACT|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694631|reactome:R-HSA-9694635|reactome:R-HSA-9694686|reactome:R-HSA-9694786 refseq:NP_004695.1|ensembl:ENSG00000114767(gene)|ensembl:ENST00000232888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR039241|rcsb pdb:4J0W|rcsb pdb:4JXM|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:duUiCXyS98OXMbfCdv4gp2blWT42697049 rogid:AxnPDovGXO2JPghV7c6ztiV1/z89606 rigid:o5CLvCpDhmskxSJGvv1PBkfRC68 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC2 uniprotkb:Q9C0B5 intact:EBI-25474821 intact:EBI-2799626|uniprotkb:Q8TAK8|uniprotkb:Q9H923|uniprotkb:Q9UFI7|uniprotkb:Q6ZMF0|uniprotkb:Q2TGF0|ensembl:ENSP00000287169 psi-mi:spike_sars2(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:zdhc5_human(display_long)|uniprotkb:KIAA1748(gene name synonym)|uniprotkb:ZNF375(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 5(gene name synonym)|uniprotkb:Zinc finger protein 375(gene name synonym)|uniprotkb:ZDHHC5(gene name)|psi-mi:ZDHHC5(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375343|imex:IM-28441-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043002|interpro:IPR044873|rcsb pdb:7MJI|rcsb pdb:7MJJ|rcsb pdb:7MJK|rcsb pdb:7MJL|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7MKB|rcsb pdb:7MKL|rcsb pdb:7MKM|rcsb pdb:7MMO|rcsb pdb:7MY2|rcsb pdb:7MY3|rcsb pdb:7N0G|rcsb pdb:7N0H|rcsb pdb:7NEG|rcsb pdb:7NKT|rcsb pdb:7NT9|rcsb pdb:7NTA|rcsb pdb:7NTC|rcsb pdb:7NX6|rcsb pdb:7NX7|rcsb pdb:7NX8|rcsb pdb:7NX9|rcsb pdb:7NXA|rcsb pdb:7NXB|rcsb pdb:7NXC|rcsb pdb:7AKD|rcsb pdb:7B14|rcsb pdb:7B18|rcsb pdb:7B62|rcsb pdb:7C53|rcsb pdb:7CHO|rcsb pdb:7CHP|rcsb pdb:7CHS|rcsb pdb:7CN4|rcsb pdb:7CWT|rcsb pdb:7CYH|rcsb pdb:7CYP|rcsb pdb:7CZP|rcsb pdb:7CZQ|rcsb pdb:7CZR|rcsb pdb:7CZS|rcsb pdb:7CZT|rcsb pdb:7CZU|rcsb pdb:7CZV|rcsb pdb:7CZW|rcsb pdb:7CZX|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7D00|rcsb pdb:7D03|rcsb pdb:7D0B|rcsb pdb:7D0C|rcsb pdb:7D0D|rcsb pdb:7D4G|rcsb pdb:7DEO|rcsb pdb:7DET|rcsb pdb:7DEU|interpro:IPR044874|rcsb pdb:7DJZ|rcsb pdb:7DK0|rcsb pdb:7DWX|rcsb pdb:7DWY|rcsb pdb:7DWZ|rcsb pdb:7DX0|rcsb pdb:7DX1|rcsb pdb:7DX2|rcsb pdb:7DX3|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7DZW|rcsb pdb:7DZX|rcsb pdb:7DZY|rcsb pdb:7E23|rcsb pdb:7E3J|rcsb pdb:7E5Y|rcsb pdb:7E7B|rcsb pdb:7E7D|rcsb pdb:7E7X|rcsb pdb:7E7Y|rcsb pdb:7E86|rcsb pdb:7E88|rcsb pdb:7E8C|rcsb pdb:7E8F|rcsb pdb:7E8M|rcsb pdb:7EAM|rcsb pdb:7EAN|rcsb pdb:7EAZ|rcsb pdb:7EB0|rcsb pdb:7EB3|rcsb pdb:7EB4|rcsb pdb:7EB5|rcsb pdb:7EJ4|rcsb pdb:7EJ5|rcsb pdb:7EK6|rcsb pdb:7KFV|rcsb pdb:7KFW|rcsb pdb:7KFX|rcsb pdb:7KFY|rcsb pdb:7KQB|rcsb pdb:7KQE|rcsb pdb:7KRQ|rcsb pdb:7KRR|rcsb pdb:7KRS|rcsb pdb:7L2D|rcsb pdb:7L2E|rcsb pdb:7L2F|rcsb pdb:7L4Z|rcsb pdb:7L56|rcsb pdb:7L57|rcsb pdb:7L58|rcsb pdb:7LAA|rcsb pdb:7LAB|rcsb pdb:7LC8|rcsb pdb:7LDJ|rcsb pdb:7LJR|rcsb pdb:7LM8|rcsb pdb:7LO4|rcsb pdb:7LQV|rcsb pdb:7LQW|rcsb pdb:7LS9|rcsb pdb:7LSS|rcsb pdb:7LWI|rcsb pdb:7LWJ|rcsb pdb:7LWK|rcsb pdb:7LWL|rcsb pdb:7LWM|rcsb pdb:7LWN|rcsb pdb:7LWO|rcsb pdb:7LWP|rcsb pdb:7LWQ|rcsb pdb:7LWS|rcsb pdb:7LWT|rcsb pdb:7LWU|rcsb pdb:7LWV|rcsb pdb:7LWW|rcsb pdb:7LX5|rcsb pdb:7LXW|rcsb pdb:7LXX|rcsb pdb:7LXY|rcsb pdb:7LXZ|rcsb pdb:7LY0|rcsb pdb:7LY2|rcsb pdb:7LY3|rcsb pdb:7LYK|rcsb pdb:7LYL|rcsb pdb:7LYM|rcsb pdb:7LYN|rcsb pdb:7LYO|rcsb pdb:7LYP|rcsb pdb:7LYQ|rcsb pdb:7M0J|rcsb pdb:7M6D|rcsb pdb:7M6E|rcsb pdb:7M6F|rcsb pdb:7M6G|rcsb pdb:7M6H|rcsb pdb:7M6I|rcsb pdb:7M71|rcsb pdb:7M7B|rcsb pdb:7M7W|rcsb pdb:7M8J|rcsb pdb:7M8K|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MF1|rcsb pdb:7MFU|rcsb pdb:7M3I|rcsb pdb:7M53|rcsb pdb:7MJG|rcsb pdb:7MJH|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|interpro:IPR043473|rcsb pdb:6LZG|rcsb pdb:6VW1|rcsb pdb:6YLA|rcsb pdb:6YM0|rcsb pdb:6YOR|rcsb pdb:7BZ5|refseq:YP_009724390.1|rcsb pdb:7KMG|rcsb pdb:7KMH|rcsb pdb:7KMI|rcsb pdb:7KMK|rcsb pdb:7KML|rcsb pdb:7KN5|rcsb pdb:7KN6|rcsb pdb:7KN7|rcsb pdb:7KS9|rcsb pdb:7KSG|rcsb pdb:7KXJ|rcsb pdb:7KXK|rcsb pdb:7KZB|rcsb pdb:7L0N|rcsb pdb:7L2C|rcsb pdb:7L3N|rcsb pdb:7L5B|rcsb pdb:7L7F|rcsb pdb:7L7K|rcsb pdb:7LCN|rcsb pdb:7LD1|rcsb pdb:7LOP|rcsb pdb:7ND3|rcsb pdb:7ND4|rcsb pdb:7ND5|rcsb pdb:7ND6|rcsb pdb:7ND7|rcsb pdb:7ND8|rcsb pdb:7ND9|rcsb pdb:7NDA|rcsb pdb:7NDB|rcsb pdb:7NDC|rcsb pdb:7NDD|rcsb pdb:7NEH|rcsb pdb:7B17|rcsb pdb:7BEH|rcsb pdb:7BEI|rcsb pdb:7BEJ|rcsb pdb:7BEK|rcsb pdb:7BEL|rcsb pdb:7BEM|rcsb pdb:7BEN|rcsb pdb:7BEO|rcsb pdb:7BEP|rcsb pdb:7C8J|rcsb pdb:7CAC|rcsb pdb:7CM4|rcsb pdb:7CWL|rcsb pdb:7D2Z|rcsb pdb:7D30|rcsb pdb:7DPM|rcsb pdb:7KGJ|rcsb pdb:7KGK|rcsb pdb:7KLG|rcsb pdb:7KLH|rcsb pdb:7KLW|interpro:IPR042578|rcsb pdb:7CAB|interpro:IPR044341|rcsb pdb:7CDI|interpro:IPR044366|rcsb pdb:7CDJ|rcsb pdb:6ZLR|rcsb pdb:7CJF|rcsb pdb:7CT5|rcsb pdb:7A25|rcsb pdb:7CWM|rcsb pdb:7CWN|rcsb pdb:7CWO|rcsb pdb:7CWS|rcsb pdb:7CWU|rcsb pdb:7DCC|rcsb pdb:7DCX|rcsb pdb:7DD2|rcsb pdb:7DD8|rcsb pdb:7DDD|rcsb pdb:7DDN|rcsb pdb:7DF3|rcsb pdb:7DF4|rcsb pdb:7DK3|rcsb pdb:7DK4|rcsb pdb:7DK5|rcsb pdb:7DK6|rcsb pdb:7DK7|rcsb pdb:7DMU|rcsb pdb:7JVB|rcsb pdb:7JWY|rcsb pdb:7K8M|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KJ5|rcsb pdb:7KKK|rcsb pdb:7KKL|rcsb pdb:7KL9|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7KNI|rcsb pdb:7L02|rcsb pdb:7L06|rcsb pdb:7L09|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR036326|rcsb pdb:6M17|rcsb pdb:6VSB|rcsb pdb:6VXX|rcsb pdb:6VYB|rcsb pdb:6LVN|rcsb pdb:6LXT|rcsb pdb:6M0J|rcsb pdb:6W41|interpro:IPR032500|interpro:IPR043607|rcsb pdb:6M1V|rcsb pdb:6WPS|rcsb pdb:6WPT|rcsb pdb:6X29|rcsb pdb:6X2A|rcsb pdb:6X2B|rcsb pdb:6X2C|rcsb pdb:6X6P|rcsb pdb:6XC2|rcsb pdb:6XC3|rcsb pdb:6XC4|rcsb pdb:6XC7|rcsb pdb:6XCM|rcsb pdb:6XCN|rcsb pdb:6XDG|rcsb pdb:6XE1|rcsb pdb:6XEY|rcsb pdb:6XKL|rcsb pdb:6XR8|rcsb pdb:6XRA|rcsb pdb:6XS6|rcsb pdb:6YZ5|rcsb pdb:6YZ7|rcsb pdb:6Z2M|rcsb pdb:6Z43|rcsb pdb:6ZCZ|rcsb pdb:6ZDH|rcsb pdb:6ZER|rcsb pdb:6ZFO|rcsb pdb:6ZGE|rcsb pdb:6ZGG|rcsb pdb:6ZGI|rcsb pdb:6ZOX|rcsb pdb:6ZOY|rcsb pdb:6ZOZ|rcsb pdb:6ZP0|rcsb pdb:6ZP1|rcsb pdb:6ZP2|rcsb pdb:7BWJ|rcsb pdb:7BYR|rcsb pdb:7C01|rcsb pdb:7C2L|rcsb pdb:7C8V|rcsb pdb:7C8W|rcsb pdb:7CAN|rcsb pdb:6X79|rcsb pdb:6XF5|rcsb pdb:6XF6|rcsb pdb:6XLU|rcsb pdb:6XM0|rcsb pdb:6XM3|rcsb pdb:6XM4|rcsb pdb:6XM5|rcsb pdb:6Z97|rcsb pdb:6ZBP|rcsb pdb:6ZDG|rcsb pdb:6ZH9|rcsb pdb:6ZHD|rcsb pdb:6ZOW|rcsb pdb:6ZP5|rcsb pdb:6ZP7|rcsb pdb:6ZWV|rcsb pdb:7C8D|rcsb pdb:7CAH|rcsb pdb:7CN9|rcsb pdb:7JJI|rcsb pdb:7JJJ|rcsb pdb:7JMO|rcsb pdb:7JMP|rcsb pdb:6XKP|rcsb pdb:6XKQ|rcsb pdb:6ZB4|rcsb pdb:6ZB5|rcsb pdb:6ZXN|rcsb pdb:7A29|rcsb pdb:7A4N|rcsb pdb:7A5R|rcsb pdb:7A5S|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A93|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7AD1|rcsb pdb:7CAI|rcsb pdb:7CAK|rcsb pdb:7CH4|rcsb pdb:7CH5|rcsb pdb:7CHB|rcsb pdb:7CHC|rcsb pdb:7CHE|rcsb pdb:7CHF|rcsb pdb:7CHH|rcsb pdb:7JJC|rcsb pdb:7JMW|rcsb pdb:7JV2|rcsb pdb:7JV4|rcsb pdb:7JV6|rcsb pdb:7JVA|rcsb pdb:7JVC|rcsb pdb:7JW0|rcsb pdb:7JWB|rcsb pdb:7JX3|rcsb pdb:7JZL|rcsb pdb:7JZM|rcsb pdb:7JZN|rcsb pdb:7JZU|rcsb pdb:7K43|rcsb pdb:7K45|rcsb pdb:7K4N|rcsb pdb:7K8S|rcsb pdb:7K8T|rcsb pdb:7K8U|rcsb pdb:7K8V|rcsb pdb:7K8W|rcsb pdb:7K8X|rcsb pdb:7K8Y|rcsb pdb:7K8Z|rcsb pdb:7K90|rcsb pdb:7K9Z|rcsb pdb:7KDG|rcsb pdb:7KDH|rcsb pdb:7KDI|rcsb pdb:7KDJ|rcsb pdb:7KDK|rcsb pdb:7KDL|rcsb pdb:7KE4|rcsb pdb:7KE6|rcsb pdb:7KE7|rcsb pdb:7KE8|rcsb pdb:7KE9|rcsb pdb:7KEA|rcsb pdb:7KEB|rcsb pdb:7KEC|reactome:R-HSA-9694322|reactome:R-HSA-9694548|reactome:R-HSA-9694614|reactome:R-HSA-9694635 refseq:XP_011543201.1|refseq:XP_011543202.1|refseq:XP_011543203.1|refseq:NP_056272.2|ensembl:ENSG00000156599(gene)|ensembl:ENST00000287169(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030425"(dendrite)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0062208"(positive regulation of pattern recognition receptor signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905171"(positive regulation of protein localization to phagocytic vesicle)|interpro:IPR001594(Zinc finger, DHHC-type) - - - figure legend:Table 2, no 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/22 rogid:QpTiyy2B+5c9PtFcZD+nZTX7nng2697049 rogid:4EKCQeKXifPU/7fv6uPuHE7b1rU9606 rigid:dL8g/uJFHgEaDhtmsjVQ9dJc5nM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC2 uniprotkb:Q7Z5G4 intact:EBI-25474821 intact:EBI-4403685|ensembl:ENSP00000350378|ensembl:ENSP00000429329|ensembl:ENSP00000429480|uniprotkb:D3DSX9|uniprotkb:Q96EQ4|uniprotkb:Q9P1S0|uniprotkb:Q9Y5U7|uniprotkb:J3KQ24 psi-mi:spike_sars2(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:goga7_human(display_long)|uniprotkb:GOLGA7(gene name)|psi-mi:GOLGA7(display_short)|uniprotkb:GCP16(gene name synonym)|uniprotkb:Golgi complex-associated protein of 16 kDa(gene name synonym)|uniprotkb:HDCKB03P(orf name)|uniprotkb:HSPC041(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375343|imex:IM-28441-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR043002|interpro:IPR044873|rcsb pdb:7MJI|rcsb pdb:7MJJ|rcsb pdb:7MJK|rcsb pdb:7MJL|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7MKB|rcsb pdb:7MKL|rcsb pdb:7MKM|rcsb pdb:7MMO|rcsb pdb:7MY2|rcsb pdb:7MY3|rcsb pdb:7N0G|rcsb pdb:7N0H|rcsb pdb:7NEG|rcsb pdb:7NKT|rcsb pdb:7NT9|rcsb pdb:7NTA|rcsb pdb:7NTC|rcsb pdb:7NX6|rcsb pdb:7NX7|rcsb pdb:7NX8|rcsb pdb:7NX9|rcsb pdb:7NXA|rcsb pdb:7NXB|rcsb pdb:7NXC|rcsb pdb:7AKD|rcsb pdb:7B14|rcsb pdb:7B18|rcsb pdb:7B62|rcsb pdb:7C53|rcsb pdb:7CHO|rcsb pdb:7CHP|rcsb pdb:7CHS|rcsb pdb:7CN4|rcsb pdb:7CWT|rcsb pdb:7CYH|rcsb pdb:7CYP|rcsb pdb:7CZP|rcsb pdb:7CZQ|rcsb pdb:7CZR|rcsb pdb:7CZS|rcsb pdb:7CZT|rcsb pdb:7CZU|rcsb pdb:7CZV|rcsb pdb:7CZW|rcsb pdb:7CZX|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:7D00|rcsb pdb:7D03|rcsb pdb:7D0B|rcsb pdb:7D0C|rcsb pdb:7D0D|rcsb pdb:7D4G|rcsb pdb:7DEO|rcsb pdb:7DET|rcsb pdb:7DEU|interpro:IPR044874|rcsb pdb:7DJZ|rcsb pdb:7DK0|rcsb pdb:7DWX|rcsb pdb:7DWY|rcsb pdb:7DWZ|rcsb pdb:7DX0|rcsb pdb:7DX1|rcsb pdb:7DX2|rcsb pdb:7DX3|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7DZW|rcsb pdb:7DZX|rcsb pdb:7DZY|rcsb pdb:7E23|rcsb pdb:7E3J|rcsb pdb:7E5Y|rcsb pdb:7E7B|rcsb pdb:7E7D|rcsb pdb:7E7X|rcsb pdb:7E7Y|rcsb pdb:7E86|rcsb pdb:7E88|rcsb pdb:7E8C|rcsb pdb:7E8F|rcsb pdb:7E8M|rcsb pdb:7EAM|rcsb pdb:7EAN|rcsb pdb:7EAZ|rcsb pdb:7EB0|rcsb pdb:7EB3|rcsb pdb:7EB4|rcsb pdb:7EB5|rcsb pdb:7EJ4|rcsb pdb:7EJ5|rcsb pdb:7EK6|rcsb pdb:7KFV|rcsb pdb:7KFW|rcsb pdb:7KFX|rcsb pdb:7KFY|rcsb pdb:7KQB|rcsb pdb:7KQE|rcsb pdb:7KRQ|rcsb pdb:7KRR|rcsb pdb:7KRS|rcsb pdb:7L2D|rcsb pdb:7L2E|rcsb pdb:7L2F|rcsb pdb:7L4Z|rcsb pdb:7L56|rcsb pdb:7L57|rcsb pdb:7L58|rcsb pdb:7LAA|rcsb pdb:7LAB|rcsb pdb:7LC8|rcsb pdb:7LDJ|rcsb pdb:7LJR|rcsb pdb:7LM8|rcsb pdb:7LO4|rcsb pdb:7LQV|rcsb pdb:7LQW|rcsb pdb:7LS9|rcsb pdb:7LSS|rcsb pdb:7LWI|rcsb pdb:7LWJ|rcsb pdb:7LWK|rcsb pdb:7LWL|rcsb pdb:7LWM|rcsb pdb:7LWN|rcsb pdb:7LWO|rcsb pdb:7LWP|rcsb pdb:7LWQ|rcsb pdb:7LWS|rcsb pdb:7LWT|rcsb pdb:7LWU|rcsb pdb:7LWV|rcsb pdb:7LWW|rcsb pdb:7LX5|rcsb pdb:7LXW|rcsb pdb:7LXX|rcsb pdb:7LXY|rcsb pdb:7LXZ|rcsb pdb:7LY0|rcsb pdb:7LY2|rcsb pdb:7LY3|rcsb pdb:7LYK|rcsb pdb:7LYL|rcsb pdb:7LYM|rcsb pdb:7LYN|rcsb pdb:7LYO|rcsb pdb:7LYP|rcsb pdb:7LYQ|rcsb pdb:7M0J|rcsb pdb:7M6D|rcsb pdb:7M6E|rcsb pdb:7M6F|rcsb pdb:7M6G|rcsb pdb:7M6H|rcsb pdb:7M6I|rcsb pdb:7M71|rcsb pdb:7M7B|rcsb pdb:7M7W|rcsb pdb:7M8J|rcsb pdb:7M8K|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MF1|rcsb pdb:7MFU|rcsb pdb:7M3I|rcsb pdb:7M53|rcsb pdb:7MJG|rcsb pdb:7MJH|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|interpro:IPR043473|rcsb pdb:6LZG|rcsb pdb:6VW1|rcsb pdb:6YLA|rcsb pdb:6YM0|rcsb pdb:6YOR|rcsb pdb:7BZ5|refseq:YP_009724390.1|rcsb pdb:7KMG|rcsb pdb:7KMH|rcsb pdb:7KMI|rcsb pdb:7KMK|rcsb pdb:7KML|rcsb pdb:7KN5|rcsb pdb:7KN6|rcsb pdb:7KN7|rcsb pdb:7KS9|rcsb pdb:7KSG|rcsb pdb:7KXJ|rcsb pdb:7KXK|rcsb pdb:7KZB|rcsb pdb:7L0N|rcsb pdb:7L2C|rcsb pdb:7L3N|rcsb pdb:7L5B|rcsb pdb:7L7F|rcsb pdb:7L7K|rcsb pdb:7LCN|rcsb pdb:7LD1|rcsb pdb:7LOP|rcsb pdb:7ND3|rcsb pdb:7ND4|rcsb pdb:7ND5|rcsb pdb:7ND6|rcsb pdb:7ND7|rcsb pdb:7ND8|rcsb pdb:7ND9|rcsb pdb:7NDA|rcsb pdb:7NDB|rcsb pdb:7NDC|rcsb pdb:7NDD|rcsb pdb:7NEH|rcsb pdb:7B17|rcsb pdb:7BEH|rcsb pdb:7BEI|rcsb pdb:7BEJ|rcsb pdb:7BEK|rcsb pdb:7BEL|rcsb pdb:7BEM|rcsb pdb:7BEN|rcsb pdb:7BEO|rcsb pdb:7BEP|rcsb pdb:7C8J|rcsb pdb:7CAC|rcsb pdb:7CM4|rcsb pdb:7CWL|rcsb pdb:7D2Z|rcsb pdb:7D30|rcsb pdb:7DPM|rcsb pdb:7KGJ|rcsb pdb:7KGK|rcsb pdb:7KLG|rcsb pdb:7KLH|rcsb pdb:7KLW|interpro:IPR042578|rcsb pdb:7CAB|interpro:IPR044341|rcsb pdb:7CDI|interpro:IPR044366|rcsb pdb:7CDJ|rcsb pdb:6ZLR|rcsb pdb:7CJF|rcsb pdb:7CT5|rcsb pdb:7A25|rcsb pdb:7CWM|rcsb pdb:7CWN|rcsb pdb:7CWO|rcsb pdb:7CWS|rcsb pdb:7CWU|rcsb pdb:7DCC|rcsb pdb:7DCX|rcsb pdb:7DD2|rcsb pdb:7DD8|rcsb pdb:7DDD|rcsb pdb:7DDN|rcsb pdb:7DF3|rcsb pdb:7DF4|rcsb pdb:7DK3|rcsb pdb:7DK4|rcsb pdb:7DK5|rcsb pdb:7DK6|rcsb pdb:7DK7|rcsb pdb:7DMU|rcsb pdb:7JVB|rcsb pdb:7JWY|rcsb pdb:7K8M|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KJ5|rcsb pdb:7KKK|rcsb pdb:7KKL|rcsb pdb:7KL9|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7KNI|rcsb pdb:7L02|rcsb pdb:7L06|rcsb pdb:7L09|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR036326|rcsb pdb:6M17|rcsb pdb:6VSB|rcsb pdb:6VXX|rcsb pdb:6VYB|rcsb pdb:6LVN|rcsb pdb:6LXT|rcsb pdb:6M0J|rcsb pdb:6W41|interpro:IPR032500|interpro:IPR043607|rcsb pdb:6M1V|rcsb pdb:6WPS|rcsb pdb:6WPT|rcsb pdb:6X29|rcsb pdb:6X2A|rcsb pdb:6X2B|rcsb pdb:6X2C|rcsb pdb:6X6P|rcsb pdb:6XC2|rcsb pdb:6XC3|rcsb pdb:6XC4|rcsb pdb:6XC7|rcsb pdb:6XCM|rcsb pdb:6XCN|rcsb pdb:6XDG|rcsb pdb:6XE1|rcsb pdb:6XEY|rcsb pdb:6XKL|rcsb pdb:6XR8|rcsb pdb:6XRA|rcsb pdb:6XS6|rcsb pdb:6YZ5|rcsb pdb:6YZ7|rcsb pdb:6Z2M|rcsb pdb:6Z43|rcsb pdb:6ZCZ|rcsb pdb:6ZDH|rcsb pdb:6ZER|rcsb pdb:6ZFO|rcsb pdb:6ZGE|rcsb pdb:6ZGG|rcsb pdb:6ZGI|rcsb pdb:6ZOX|rcsb pdb:6ZOY|rcsb pdb:6ZOZ|rcsb pdb:6ZP0|rcsb pdb:6ZP1|rcsb pdb:6ZP2|rcsb pdb:7BWJ|rcsb pdb:7BYR|rcsb pdb:7C01|rcsb pdb:7C2L|rcsb pdb:7C8V|rcsb pdb:7C8W|rcsb pdb:7CAN|rcsb pdb:6X79|rcsb pdb:6XF5|rcsb pdb:6XF6|rcsb pdb:6XLU|rcsb pdb:6XM0|rcsb pdb:6XM3|rcsb pdb:6XM4|rcsb pdb:6XM5|rcsb pdb:6Z97|rcsb pdb:6ZBP|rcsb pdb:6ZDG|rcsb pdb:6ZH9|rcsb pdb:6ZHD|rcsb pdb:6ZOW|rcsb pdb:6ZP5|rcsb pdb:6ZP7|rcsb pdb:6ZWV|rcsb pdb:7C8D|rcsb pdb:7CAH|rcsb pdb:7CN9|rcsb pdb:7JJI|rcsb pdb:7JJJ|rcsb pdb:7JMO|rcsb pdb:7JMP|rcsb pdb:6XKP|rcsb pdb:6XKQ|rcsb pdb:6ZB4|rcsb pdb:6ZB5|rcsb pdb:6ZXN|rcsb pdb:7A29|rcsb pdb:7A4N|rcsb pdb:7A5R|rcsb pdb:7A5S|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A93|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7AD1|rcsb pdb:7CAI|rcsb pdb:7CAK|rcsb pdb:7CH4|rcsb pdb:7CH5|rcsb pdb:7CHB|rcsb pdb:7CHC|rcsb pdb:7CHE|rcsb pdb:7CHF|rcsb pdb:7CHH|rcsb pdb:7JJC|rcsb pdb:7JMW|rcsb pdb:7JV2|rcsb pdb:7JV4|rcsb pdb:7JV6|rcsb pdb:7JVA|rcsb pdb:7JVC|rcsb pdb:7JW0|rcsb pdb:7JWB|rcsb pdb:7JX3|rcsb pdb:7JZL|rcsb pdb:7JZM|rcsb pdb:7JZN|rcsb pdb:7JZU|rcsb pdb:7K43|rcsb pdb:7K45|rcsb pdb:7K4N|rcsb pdb:7K8S|rcsb pdb:7K8T|rcsb pdb:7K8U|rcsb pdb:7K8V|rcsb pdb:7K8W|rcsb pdb:7K8X|rcsb pdb:7K8Y|rcsb pdb:7K8Z|rcsb pdb:7K90|rcsb pdb:7K9Z|rcsb pdb:7KDG|rcsb pdb:7KDH|rcsb pdb:7KDI|rcsb pdb:7KDJ|rcsb pdb:7KDK|rcsb pdb:7KDL|rcsb pdb:7KE4|rcsb pdb:7KE6|rcsb pdb:7KE7|rcsb pdb:7KE8|rcsb pdb:7KE9|rcsb pdb:7KEA|rcsb pdb:7KEB|rcsb pdb:7KEC|reactome:R-HSA-9694322|reactome:R-HSA-9694548|reactome:R-HSA-9694614|reactome:R-HSA-9694635 ensembl:ENSG00000147533(gene)|ensembl:ENST00000357743(transcript)|ensembl:ENST00000518270(transcript)|ensembl:ENST00000520817(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002178"(palmitoyltransferase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005795"(Golgi stack)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0018230"(peptidyl-L-cysteine S-palmitoylation)|go:"GO:0031228"(intrinsic component of Golgi membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR019383|reactome:R-HSA-6798695|reactome:R-HSA-9648002|refseq:NP_001002296.1|refseq:NP_057183.2|refseq:NP_001167595.1 - - - figure legend:Table 2, no 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/22 rogid:QpTiyy2B+5c9PtFcZD+nZTX7nng2697049 rogid:NV93lzMDdykrGhl0NkCKYso0t+A9606 rigid:dL8g/uJFHgEaDhtmsjVQ9dJc5nM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449619 uniprotkb:Q99959 intact:EBI-25475847 intact:EBI-702235|intact:EBI-2692870|uniprotkb:D3DUW9|uniprotkb:Q99960|uniprotkb:Q4VC01|uniprotkb:B8QFA1|uniprotkb:B8QGS6|uniprotkb:B8QGS7|uniprotkb:A0AV37|ensembl:ENSP00000070846 psi-mi:p0dtd1-pro_0000449619(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pkp2_human(display_long)|uniprotkb:PKP2(gene name)|psi-mi:PKP2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375358|imex:IM-28441-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_004563.2|refseq:NP_001005242.2|ensembl:ENSG00000057294(gene)|ensembl:ENST00000070846(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002159"(desmosome assembly)|go:"GO:0002934"(desmosome organization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007507"(heart development)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:Q99959|rcsb pdb:3TT9|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:SaSNaqNfTqsYEpmhXnBT8bJZczM2697049 rogid:kwGWMlk4SDz0xARlBMD1dY9fehQ9606 rigid:MUKWer2ugnCqIsU1jcMkDd8I7rE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449619 uniprotkb:Q8NBJ5 intact:EBI-25475847 intact:EBI-1057068|uniprotkb:Q8NC64|ensembl:ENSP00000252599 psi-mi:p0dtd1-pro_0000449619(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gt251_human(display_long)|uniprotkb:COLGALT1(gene name)|psi-mi:COLGALT1(display_short)|uniprotkb:"Collagen beta(1-O)galactosyltransferase 1"(gene name synonym)|uniprotkb:GLT25D1(gene name synonym)|uniprotkb:Glycosyltransferase 25 family member 1(gene name synonym)|uniprotkb:Hydroxylysine galactosyltransferase 1(gene name synonym)|uniprotkb:PSEC0241(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375358|imex:IM-28441-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_078932.2|ensembl:ENSG00000130309(gene)|ensembl:ENST00000252599(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:1904028"(positive regulation of collagen fibril organization)|interpro:IPR002654(Glycosyl transferase, family 25)|interpro:IPR029044|mint:Q8NBJ5|reactome:R-HSA-1650814 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:SaSNaqNfTqsYEpmhXnBT8bJZczM2697049 rogid:nB7wFmsUKfA2+PrPaqw08fQpJRs9606 rigid:MUKWer2ugnCqIsU1jcMkDd8I7rE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449619 uniprotkb:Q14181 intact:EBI-25475847 intact:EBI-712752|ensembl:ENSP00000265465|uniprotkb:Q9BPV3|uniprotkb:B4DNB4 psi-mi:p0dtd1-pro_0000449619(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dpoa2_human(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:POLA2(gene name)|psi-mi:POLA2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375358|imex:IM-28441-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) reactome:R-HSA-69183|reactome:R-HSA-69166|reactome:R-HSA-9710421|ensembl:ENSG00000014138(gene)|ensembl:ENST00000265465(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|rcsb pdb:2KEB|rcsb pdb:4E2I|rcsb pdb:4Y97|rcsb pdb:5EXR|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|refseq:NP_002680.2 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:SaSNaqNfTqsYEpmhXnBT8bJZczM2697049 rogid:cPvK8qerkbSbnl1+TAIlBqTuEFU9606 rigid:MUKWer2ugnCqIsU1jcMkDd8I7rE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449619 uniprotkb:P09884 intact:EBI-25475847 intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349 psi-mi:p0dtd1-pro_0000449619(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375358|imex:IM-28441-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:SaSNaqNfTqsYEpmhXnBT8bJZczM2697049 rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606 rigid:MUKWer2ugnCqIsU1jcMkDd8I7rE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449619 uniprotkb:P49643 intact:EBI-25475847 intact:EBI-850004|uniprotkb:Q53FJ8|uniprotkb:Q6P1Q7|uniprotkb:Q8WVL2|uniprotkb:Q9H413|ensembl:ENSP00000484105 psi-mi:p0dtd1-pro_0000449619(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pri2_human(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:PRIM2(gene name)|psi-mi:PRIM2(display_short)|uniprotkb:PRIM2A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375358|imex:IM-28441-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001269416.1|refseq:NP_001269417.1|refseq:NP_000938.2|dip:DIP-36438N|ensembl:ENSG00000146143(gene)|ensembl:ENST00000615550(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|mint:P49643|rcsb pdb:3L9Q|rcsb pdb:3Q36|rcsb pdb:4BPU|rcsb pdb:4BPW|rcsb pdb:4BPX|rcsb pdb:4RR2|rcsb pdb:5DQO|rcsb pdb:5EXR|rcsb pdb:5F0Q|rcsb pdb:5F0S|rcsb pdb:5I7M|rcsb pdb:6DHW|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-9710421 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:SaSNaqNfTqsYEpmhXnBT8bJZczM2697049 rogid:WL5i+CvK52C93/3X4a3MFQvD0JQ9606 rigid:MUKWer2ugnCqIsU1jcMkDd8I7rE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449619 uniprotkb:P49642 intact:EBI-25475847 intact:EBI-726050|ensembl:ENSP00000350491 psi-mi:p0dtd1-pro_0000449619(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pri1_human(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:PRIM1(gene name)|psi-mi:PRIM1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375358|imex:IM-28441-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000198056(gene)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|refseq:NP_000937.1|rcsb pdb:4BPU|rcsb pdb:4BPW|ensembl:ENST00000338193(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0032553"(ribonucleotide binding)|rcsb pdb:4BPX|rcsb pdb:4LIK|interpro:IPR002755(DNA primase, small subunit)|rcsb pdb:4LIL|rcsb pdb:4MHQ|rcsb pdb:4RR2|rcsb pdb:5EXR|rcsb pdb:6R4S|rcsb pdb:6R4T|rcsb pdb:6R4U|rcsb pdb:6R5D|rcsb pdb:6R5E|rcsb pdb:6RB4|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-9710421 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:SaSNaqNfTqsYEpmhXnBT8bJZczM2697049 rogid:bgNj0hjvHPliBXVfkZmg7v0N/uw9606 rigid:MUKWer2ugnCqIsU1jcMkDd8I7rE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449628 uniprotkb:Q9HAV7 intact:EBI-25475880 intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954 psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375371|imex:IM-28441-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1 - chain-seq-start:4254|chain-seq-end:4392 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606 rigid:Z8JNNLeEXn0WXUPhk39T8mVM4IM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449628 uniprotkb:Q96CW1 intact:EBI-25475880 intact:EBI-297683|ensembl:ENSP00000292807|uniprotkb:A6NE12|uniprotkb:P20172|uniprotkb:P53679|uniprotkb:D3DNT1 psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ap2m1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:AP2M1(gene name)|psi-mi:AP2M1(display_short)|uniprotkb:CLAPM1(gene name synonym)|uniprotkb:KIAA0109(gene name synonym)|uniprotkb:Adaptin-mu2(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:HA2 50 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375371|imex:IM-28441-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000161203(gene)|ensembl:ENST00000292807(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0034622"|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0031623"(receptor internalization)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:Q96CW1|rcsb pdb:1H6E|rcsb pdb:6BNT|rcsb pdb:6URI|reactome:R-HSA-164939|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|reactome:R-HSA-182218|refseq:NP_001020376.1|refseq:NP_004059.2|refseq:NP_001298127.1 - chain-seq-start:4254|chain-seq-end:4392 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA9606 rigid:Z8JNNLeEXn0WXUPhk39T8mVM4IM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449628 uniprotkb:Q969X5 intact:EBI-25475880 intact:EBI-781527|uniprotkb:Q9H0L0|uniprotkb:Q9H2J2|uniprotkb:Q9ULN9|ensembl:ENSP00000377374 psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ergi1_human(display_long)|uniprotkb:ER-Golgi intermediate compartment 32 kDa protein(gene name synonym)|uniprotkb:ERGIC1(gene name)|psi-mi:ERGIC1(display_short)|uniprotkb:KIAA1181(gene name synonym)|uniprotkb:HT034(orf name)|uniprotkb:ERGIC32(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375371|imex:IM-28441-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_006714955.1|refseq:NP_001026881.1|ensembl:ENSG00000113719(gene)|ensembl:ENST00000393784(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542 - chain-seq-start:4254|chain-seq-end:4392 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rogid:UbuPGmvwVwrwg/LT5oAn9pLs5Hw9606 rigid:Z8JNNLeEXn0WXUPhk39T8mVM4IM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449628 uniprotkb:P55789 intact:EBI-25475880 intact:EBI-718281|uniprotkb:Q8TAH6|uniprotkb:Q9H290|uniprotkb:Q9UK40|intact:EBI-6137916|uniprotkb:Q53YM6|ensembl:ENSP00000248114 psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:alr_human(display_long)|uniprotkb:Augmenter of liver regeneration(gene name synonym)|uniprotkb:GFER(gene name)|psi-mi:GFER(display_short)|uniprotkb:ALR(gene name synonym)|uniprotkb:HERV1(gene name synonym)|uniprotkb:HPO(gene name synonym)|uniprotkb:Hepatopoietin(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375371|imex:IM-28441-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005253.3|ensembl:ENSG00000127554(gene)|ensembl:ENST00000248114(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008083"(growth factor activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR017905|interpro:IPR036774|interpro:IPR039799|rcsb pdb:3MBG|rcsb pdb:3O55|rcsb pdb:3TK0|rcsb pdb:3U2L|rcsb pdb:3U2M|rcsb pdb:3U5S|rcsb pdb:4LDK|reactome:R-HSA-1268020 - chain-seq-start:4254|chain-seq-end:4392 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rogid:ttWSaYxpd3WUg61NQC7eiybRFUg9606 rigid:Z8JNNLeEXn0WXUPhk39T8mVM4IM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449628 uniprotkb:O94973 intact:EBI-25475880 intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234 psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375371|imex:IM-28441-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENST00000448903(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O94973|reactome:R-HSA-167590|ensembl:ENSG00000183020(gene)|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191 - chain-seq-start:4254|chain-seq-end:4392 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606 rigid:Z8JNNLeEXn0WXUPhk39T8mVM4IM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC1-PRO_0000449645 uniprotkb:O75347 intact:EBI-25475882 intact:EBI-2686341|uniprotkb:B4DT30|ensembl:ENSP00000369736 psi-mi:p0dtc1-pro_0000449645(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:tbca_human(display_long)|uniprotkb:TCP1-chaperonin cofactor A(gene name synonym)|uniprotkb:Tubulin-folding cofactor A(gene name synonym)|uniprotkb:TBCA(gene name)|psi-mi:TBCA(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375386|imex:IM-28441-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_004598.1|refseq:NP_001284667.1|ensembl:ENSG00000171530(gene)|ensembl:ENST00000380377(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004226(Tubulin binding cofactor A)|interpro:IPR036126|mint:O75347|rcsb pdb:1H7C|reactome:R-HSA-389977 - chain-seq-start:4393|chain-seq-end:4405 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:/iLGC56GeyzPtebd7gws98Sj06M2697049 rogid:hETmNl4lTAEyZ89oOKuhkah5vmQ9606 rigid:o/9vbI3P28dihTdxJMLkyJhNReQ false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q9HAU0 intact:EBI-25475885 intact:EBI-945934|uniprotkb:Q86ST7|uniprotkb:A0JP03|uniprotkb:Q8N3K6|uniprotkb:Q96DY9|uniprotkb:Q9BVR4|uniprotkb:Q9C0H7|uniprotkb:Q9H924|uniprotkb:Q9NVK8|uniprotkb:B4DGS1|uniprotkb:F5H0I0|uniprotkb:E9PHQ3|uniprotkb:Q6NSF8|ensembl:ENSP00000299275 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pkha5_human(display_long)|uniprotkb:PLEKHA5(gene name)|psi-mi:PLEKHA5(display_short)|uniprotkb:KIAA1686(gene name synonym)|uniprotkb:PEPP2(gene name synonym)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000299275|ensembl:ENST00000424268|ensembl:ENSP00000400411|ensembl:ENST00000429027|ensembl:ENSP00000404296|ensembl:ENST00000538714|ensembl:ENSP00000439673|ensembl:ENST00000540972|ensembl:ENSP00000439396|refseq:NP_001137293.2|refseq:NP_061885.2|refseq:NP_001177789.2|refseq:NP_001243399.1|refseq:NP_001243716.1|refseq:XP_005253457.1|refseq:XP_016874992.1|refseq:XP_011519019.1|ensembl:ENSG00000052126(gene)|ensembl:ENST00000299275(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0061458"(reproductive system development)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|mint:Q9HAU0|rcsb pdb:2DKP|reactome:R-HSA-1660499 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:22W2zdIwTLw4nNRh0dHasYDCLK49606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q9H2H8 intact:EBI-25475885 intact:EBI-751051|uniprotkb:Q86WF9|uniprotkb:Q96IA9|uniprotkb:Q9BXZ1|ensembl:ENSP00000376107 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ppil3_human(display_long)|uniprotkb:Cyclophilin-like protein PPIL3(gene name synonym)|uniprotkb:Cyclophilin J(gene name synonym)|uniprotkb:PPIL3(gene name)|psi-mi:PPIL3(display_short)|uniprotkb:Rotamase PPIL3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_115861.1|refseq:NP_570981.1|refseq:XP_011509660.1|refseq:XP_005246708.1|refseq:XP_005246709.1|refseq:XP_016859841.1|refseq:XP_016859842.1|refseq:XP_016859843.1|refseq:XP_016859844.1|refseq:XP_016859845.1|ensembl:ENSG00000240344(gene)|ensembl:ENST00000392283(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|interpro:IPR044666|mint:Q9H2H8|rcsb pdb:1XYH|rcsb pdb:2OJU|rcsb pdb:2OK3|reactome:R-HSA-72163 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:jh7wemNjeR869z1vKLwDMjiFinQ9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q99081 intact:EBI-25475885 intact:EBI-722877|uniprotkb:Q86VM2|ensembl:ENSP00000267811|ensembl:ENSP00000453737|uniprotkb:Q7Z3D9|uniprotkb:Q86TC1|uniprotkb:B4E1W1 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:htf4_human(display_long)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001309086.1|refseq:NP_003196.1|refseq:NP_996919.1|refseq:NP_996920.1|refseq:NP_996921.1|refseq:NP_996923.1|ensembl:ENSG00000140262(gene)|ensembl:ENST00000267811(transcript)|ensembl:ENST00000557843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001309080.1|refseq:NP_001293149.1|refseq:NP_001309088.1|refseq:NP_001309091.1|refseq:NP_001309094.1|dip:DIP-29403N|mint:Q99081|rcsb pdb:2KNH|rcsb pdb:4JOL|reactome:R-HSA-525793|reactome:R-HSA-8939236|reactome:R-HSA-9031628 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:XnBrmDaoz2JZQ66PCjfJsmaQ6209606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q96IZ5 intact:EBI-25475885 intact:EBI-740773|uniprotkb:Q5JSN7|uniprotkb:Q5JSN8|uniprotkb:Q9H8F7|uniprotkb:Q9NV04|ensembl:ENSP00000361557 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rbm41_human(display_long)|uniprotkb:RNA-binding motif protein 41(gene name synonym)|uniprotkb:RBM41(gene name)|psi-mi:RBM41(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001164551.1|refseq:NP_060771.3|ensembl:ENSG00000089682(gene)|ensembl:ENST00000372479(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0030626"(U12 snRNA binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q96IZ5|rcsb pdb:2CPX - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:KHwyEjuJY+hrTu20ukqsVZldJx09606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q92615 intact:EBI-25475885 intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_055970.1|ensembl:ENSP00000326128|ensembl:ENSG00000107929(gene)|ensembl:ENST00000316157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3PTH - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q8IWR0 intact:EBI-25475885 intact:EBI-724271|ensembl:ENSP00000347999|ensembl:ENSP00000379773|uniprotkb:Q9NPE9|uniprotkb:D3DUG5 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:z3h7a_human(display_long)|uniprotkb:ZC3H7A(gene name)|psi-mi:ZC3H7A(display_short)|uniprotkb:ZC3H7(gene name synonym)|uniprotkb:ZC3HDC7(gene name synonym)|uniprotkb:HSPC055(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_054872.2|ensembl:ENSG00000122299(gene)|ensembl:ENST00000355758(transcript)|ensembl:ENST00000396516(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036236|interpro:IPR036855|interpro:IPR039691|mint:Q8IWR0|rcsb pdb:2D9M|refseq:XP_011520765.1|refseq:XP_006720940.1 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:9jUCQwl3/lLQ979tdqWlZ0Zszns9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q70EL1 intact:EBI-25475885 intact:EBI-946185|intact:EBI-2798236|uniprotkb:B9ZVM1|uniprotkb:A1L4Q4|uniprotkb:A3KFK3|uniprotkb:A3KFK5|uniprotkb:A3KFK6|uniprotkb:A3KFK7|uniprotkb:A6PVS4|uniprotkb:A6PVS5|uniprotkb:A6PVS6|uniprotkb:A6PVS7|uniprotkb:B3KVY1|uniprotkb:Q5F2F4|uniprotkb:Q6ZSP1|uniprotkb:Q6ZSR1|uniprotkb:Q6ZTM0|uniprotkb:Q8N1X2|uniprotkb:Q6P1N6|ensembl:ENSP00000345216 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubp54_human(display_long)|uniprotkb:C10orf29(gene name synonym)|uniprotkb:Inactive ubiquitin-specific peptidase 54(gene name synonym)|uniprotkb:USP54(gene name)|psi-mi:USP54(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_689799.3|refseq:NP_001307366.1|refseq:XP_016871263.1|refseq:XP_016871264.1|refseq:XP_016871265.1|refseq:XP_016871266.1|ensembl:ENSG00000166348(gene)|ensembl:ENST00000339859(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|interpro:IPR038765|interpro:IPR040142|mint:Q70EL1 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:TwMLO8uUiZ6onr+jyUz5D6qwZ1g9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q6UUV7 intact:EBI-25475885 intact:EBI-3453588|uniprotkb:Q9H6U2|uniprotkb:Q6DK61|uniprotkb:Q6DK62|uniprotkb:Q8NF38|ensembl:ENSP00000268184 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:crtc3_human(display_long)|uniprotkb:CRTC3(gene name)|psi-mi:CRTC3(display_short)|uniprotkb:TORC3(gene name synonym)|uniprotkb:Transducer of regulated cAMP response element-binding protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001036039.1|refseq:NP_073606.3|ensembl:ENSP00000268184|ensembl:ENST00000420329|ensembl:ENSP00000416573|dip:DIP-59211N|ensembl:ENSG00000140577(gene)|ensembl:ENST00000268184(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR024786|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-9707616|go:"GO:0005829"(cytosol)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0097009"(energy homeostasis)|interpro:IPR024783|interpro:IPR024784|interpro:IPR024785 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:OHoNJjikyJ3RLDd+Y23mUXbtLDA9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q5VUA4 intact:EBI-25475885 intact:EBI-2849257|uniprotkb:Q8NEM6|uniprotkb:Q9UNU8|uniprotkb:Q4G0E4|uniprotkb:O94796|uniprotkb:Q9Y2W9|intact:EBI-28976662|ensembl:ENSP00000354964 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zn318_human(display_long)|uniprotkb:ZNF318(gene name)|psi-mi:ZNF318(display_short)|uniprotkb:Endocrine regulatory protein(gene name synonym)|uniprotkb:HRIHFB2436(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000354964|ensembl:ENST00000605935|ensembl:ENSP00000475748|refseq:XP_011512754.1|refseq:NP_055160.2|ensembl:ENSG00000171467(gene)|ensembl:ENST00000361428(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003604(Zinc finger, U1-type) - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:HqHWYB1s5uaauSljuYFDb3/6XB49606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q5T6F2 intact:EBI-25475885 intact:EBI-2514383|ensembl:ENSP00000368540|ensembl:ENSP00000507293|ensembl:ENSP00000508372|uniprotkb:Q5JV03|uniprotkb:Q9P237|uniprotkb:Q8NC94|uniprotkb:Q6PK34|uniprotkb:Q2M2R4 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubap2_human(display_long)|uniprotkb:UBAP2(gene name)|psi-mi:UBAP2(display_short)|uniprotkb:KIAA1491(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001269458.1|refseq:NP_060919.3|ensembl:ENSG00000137073(gene)|ensembl:ENST00000379238(transcript)|ensembl:ENST00000682239(transcript)|ensembl:ENST00000684158(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045296"(cadherin binding)|go:"GO:0005634"(nucleus)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|refseq:NP_001269459.1|ensembl:ENSP00000368540|ensembl:ENSP00000507293|ensembl:ENSP00000508372 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:0bcavAC5MrP55wijYi8LYZbT6ys9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q5JSZ5 intact:EBI-25475885 intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q5EBL8 intact:EBI-25475885 intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666|ensembl:ENSP00000363578 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509(gene)|ensembl:ENST00000239666(transcript)|ensembl:ENST00000374454(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q2T9J0 intact:EBI-25475885 intact:EBI-2510623|ensembl:ENSP00000287078|uniprotkb:Q8N6H2|uniprotkb:Q5SQU1|uniprotkb:Q96AR5|uniprotkb:Q5SQT4 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tysd1_human(display_long)|uniprotkb:TYSND1(gene name)|psi-mi:TYSND1(display_short)|uniprotkb:Trypsin domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000156521(gene)|ensembl:ENST00000287078(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0042802"(identical protein binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR017345(Peptidase S1B, Tysnd1)|interpro:IPR039245|reactome:R-HSA-9033241|reactome:R-HSA-9033500|go:"GO:0004252"(serine-type endopeptidase activity)|refseq:NP_001035363.1|refseq:NP_775826.2 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:nfBCzADhPAnpbY6GasKVCOaZjjs9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q14157 intact:EBI-25475885 intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:Q13546 intact:EBI-25475885 intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|ensembl:ENSG00000137275(gene)|ensembl:ENST00000259808(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0010008"(endosome membrane)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043235"(receptor complex)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070513"(death domain binding)|go:"GO:0070926"("regulation of ATP:ADP antiporter activity")|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097342"(ripoptosome)|go:"GO:0097343"(ripoptosome assembly)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR025735|interpro:IPR037934|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9693928|go:"GO:0070266"(necroptotic process) - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:O95391 intact:EBI-25475885 intact:EBI-750559|uniprotkb:Q3LUJ0|uniprotkb:Q3LUJ1|uniprotkb:Q6RXQ5|uniprotkb:Q96FM9|uniprotkb:D3DQK2|ensembl:ENSP00000297151 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:slu7_human(display_long)|uniprotkb:SLU7(gene name)|psi-mi:SLU7(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011532720.1|refseq:NP_006416.3|ensembl:ENSG00000164609(gene)|ensembl:ENST00000297151(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000386"(second spliceosomal transesterification activity)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR021715|interpro:IPR039974|mint:O95391|rcsb pdb:5XJC|rcsb pdb:6ICZ|rcsb pdb:6QDV|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0043231"(intracellular membrane-bounded organelle) - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:AYvUYw2HWT1ZgCOR3UJMXsfm1Bc9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:O75592 intact:EBI-25475885 intact:EBI-1043774|uniprotkb:Q5JSX8|uniprotkb:Q5VZN6|uniprotkb:Q6PIB6|uniprotkb:Q9UQ11|uniprotkb:Q9Y6E4|uniprotkb:A6NJC6|ensembl:ENSP00000444596 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mycb2_human(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_055872.4|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902667"(regulation of axon guidance)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003646(Bacterial SH3-like region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR012983(PHR)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR038648|mint:O75592|rcsb pdb:5O6C|rcsb pdb:6T7F|ensembl:ENSG00000005810(gene)|ensembl:ENST00000544440(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032880"(regulation of protein localization)|dip:DIP-28142N - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:AR3FR/zd48HkVinEfdT17ItGkbU9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:O43823 intact:EBI-25475885 intact:EBI-1237481|ensembl:ENSP00000269701 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:akap8_human(display_long)|uniprotkb:AKAP8(gene name)|psi-mi:AKAP8(display_short)|uniprotkb:AKAP95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005849.1|dip:DIP-38194N|ensembl:ENSG00000105127(gene)|ensembl:ENST00000269701(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:O43823|go:"GO:0051059"(NF-kappaB binding) - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:VtRlGSvkRqrzAcnq2Fj6fToZifY9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:O14874 intact:EBI-25475885 intact:EBI-1046765|uniprotkb:Q96IN5|uniprotkb:Q6FGL4|intact:EBI-1210327|uniprotkb:A8MY43|uniprotkb:Q96G95|ensembl:ENSP00000219794|ensembl:ENSP00000378405 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:bckd_human(display_long)|uniprotkb:Branched-chain alpha-ketoacid dehydrogenase kinase(gene name synonym)|uniprotkb:BCKDK(gene name)|psi-mi:BCKDK(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005872.2|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009063"(cellular amino acid catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0045763"(negative regulation of cellular amino acid metabolic process)|go:"GO:0047323"("[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity")|interpro:IPR003594(ATP-binding region, ATPase-like)|refseq:NP_001116429.1|refseq:NP_001258855.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:O14874|reactome:R-HSA-70895|ensembl:ENSG00000103507(gene)|ensembl:ENST00000219794(transcript)|ensembl:ENST00000394951(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion) - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:0hiSb7/qtSPoHt/cmLnUo7Gq6OI9606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449629 uniprotkb:A3KN83 intact:EBI-25475885 intact:EBI-2855422|uniprotkb:Q9H3T8|uniprotkb:Q05C06|uniprotkb:Q9NVB2|uniprotkb:Q3ZTS3|ensembl:ENSP00000387361|ensembl:ENSP00000473665 psi-mi:p0dtd1-pro_0000449629(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sbno1_human(display_long)|uniprotkb:SBNO1(gene name)|psi-mi:SBNO1(display_short)|uniprotkb:MOP3(gene name synonym)|uniprotkb:Monocyte protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375395|imex:IM-28441-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011536835.1|refseq:XP_006719536.1|refseq:XP_006719537.1|refseq:XP_016875045.1|refseq:NP_001161328.1|refseq:NP_060653.3|refseq:XP_005253630.1|refseq:XP_005253633.1|ensembl:ENSG00000139697(gene)|ensembl:ENST00000420886(transcript)|ensembl:ENST00000602398(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042393"(histone binding)|interpro:IPR026741|interpro:IPR026937|interpro:IPR027417|interpro:IPR039187 - chain-seq-start:4393|chain-seq-end:5324 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:kbHtZYssQIRdvLv8DVwmVD7XSW02697049 rogid:6Cq/LZqinhg1CXC/2L1JyZygCc89606 rigid:ZqFqJWo5s6wjgIF+tNJu+s25goo false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:P17612 intact:EBI-25475888 intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:O14578 intact:EBI-25475888 intact:EBI-8623109|ensembl:ENSP00000261833|uniprotkb:Q6XUH8|intact:MINT-2795177|uniprotkb:Q2M5E1|uniprotkb:Q9UPZ7|uniprotkb:Q86UQ9 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ctro_human(display_long)|uniprotkb:CIT(gene name)|psi-mi:CIT(display_short)|uniprotkb:KIAA0949(gene name synonym)|uniprotkb:STK21(gene name synonym)|uniprotkb:CRIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 21(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000122966(gene)|ensembl:ENST00000261833(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017405(Citron Rho-interacting kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037708|mint:O14578|reactome:R-HSA-5625900|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048699"(generation of neurons)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|refseq:NP_001193928.1|refseq:NP_009105.1 - chain-seq-start:5325|chain-seq-end:5925 function:Required for KIF14 localization to the central spindle and midbody. May play a role in cytokinesis. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system|comment:mint figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:yA7y17lwftFoF2/BfbtC3aanJaI9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q9Y2I6 intact:EBI-25475888 intact:EBI-719716|uniprotkb:A6NJN0|uniprotkb:B3V9H6|uniprotkb:B7Z1V8|uniprotkb:Q8NE38|uniprotkb:Q9NQE3|intact:EBI-741715|uniprotkb:Q5JYP0|ensembl:ENSP00000278886 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ninl_human(display_long)|uniprotkb:NINL(gene name)|psi-mi:NINL(display_short)|uniprotkb:KIAA0980(gene name synonym)|uniprotkb:NLP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_079452.3|refseq:NP_001305155.1|ensembl:ENSG00000101004(gene)|ensembl:ENST00000278886(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:NAG+S5iboAG+mjX9ISJ05gY2lJY9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q9UJC3 intact:EBI-25475888 intact:EBI-746704|uniprotkb:O60561|uniprotkb:Q5TG44|uniprotkb:A8MU44|uniprotkb:B4DX15|uniprotkb:A8K8E9|intact:EBI-10969618|ensembl:ENSP00000360252 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hook1_human(display_long)|uniprotkb:HOOK1(gene name)|psi-mi:HOOK1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_056972.1|ensembl:ENSG00000134709(gene)|ensembl:ENST00000371208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007030"(Golgi organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070695"(FHF complex)|go:"GO:1905198"(manchette assembly)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR008636(HOOK)|interpro:IPR036872|interpro:IPR043936|mint:Q9UJC3 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:QOcYbuKfnNIlNKzos5v+0+A2h3I9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q9UHD2 intact:EBI-25475888 intact:EBI-356402|intact:EBI-5773956|intact:EBI-1383470|uniprotkb:Q8IYV3|uniprotkb:Q9NUJ5|ensembl:ENSP00000329967|ensembl:ENSP00000498995|uniprotkb:A8K4S4 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tbk1_human(display_long)|uniprotkb:TBK1(gene name)|psi-mi:TBK1(display_short)|uniprotkb:NAK(gene name synonym)|uniprotkb:TANK-binding kinase 1(gene name synonym)|uniprotkb:T2K(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_037386.1|go:"GO:0004672"(protein kinase activity)|ensembl:ENSG00000183735(gene)|ensembl:ENST00000331710(transcript)|ensembl:ENST00000650790(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901214"(regulation of neuron death)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR041087|interpro:IPR041309|mint:Q9UHD2|rcsb pdb:4EFO|rcsb pdb:4EUT|rcsb pdb:4EUU|rcsb pdb:4IM0|rcsb pdb:4IM2|rcsb pdb:4IM3|rcsb pdb:4IW0|rcsb pdb:4IWO|rcsb pdb:4IWP|rcsb pdb:4IWQ|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:5EP6|rcsb pdb:5W5V|rcsb pdb:6BNY|rcsb pdb:6BOD|rcsb pdb:6BOE|rcsb pdb:6CQ0|rcsb pdb:6CQ4|rcsb pdb:6CQ5|rcsb pdb:6NT9|rcsb pdb:6O8B|rcsb pdb:6RSR|rcsb pdb:6RST|rcsb pdb:6RSU|reactome:R-HSA-1606341|reactome:R-HSA-168928|reactome:R-HSA-3134975|reactome:R-HSA-3249367|reactome:R-HSA-3270619|reactome:R-HSA-9008059|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-9679191|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|refseq:XP_005268866.1|refseq:XP_005268867.1|dip:DIP-27529N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:Cf+RbPJBZTpm7XIqbAD2OEC6VEs9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q9BV73 intact:EBI-25475888 intact:EBI-1053100|uniprotkb:O14812|uniprotkb:O60588|uniprotkb:Q9H450|uniprotkb:E1P5Q3|ensembl:ENSP00000380661 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cp250_human(display_long)|uniprotkb:Centrosomal protein 2(gene name synonym)|uniprotkb:Centrosomal Nek2-associated protein 1(gene name synonym)|uniprotkb:CEP250(gene name)|psi-mi:CEP250(display_short)|uniprotkb:CEP2(gene name synonym)|uniprotkb:CNAP1(gene name synonym)|uniprotkb:250 kDa centrosomal protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_009117.2|dip:DIP-39406N|refseq:NP_001305148.1|refseq:XP_005260319.1|refseq:XP_006723753.1|refseq:XP_006723754.1|refseq:XP_006723755.1|refseq:XP_006723756.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|mint:Q9BV73|rcsb pdb:6OQA|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000126001(gene)|ensembl:ENST00000397527(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060271"(cilium assembly) - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:We+5inOR7merXjzOl/vRehewlFA9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q9BV19 intact:EBI-25475888 intact:EBI-2874661|ensembl:ENSP00000361603 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000164008(gene)|ensembl:ENST00000372525(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR019534|refseq:NP_077002.2 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q9BQS8 intact:EBI-25475888 intact:EBI-2869338|uniprotkb:Q96IV5|uniprotkb:Q3MJE6|uniprotkb:Q8TEF9|uniprotkb:Q86T41|uniprotkb:Q9H8P9|uniprotkb:Q86TB1|uniprotkb:B7ZKT7|ensembl:ENSP00000296137 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fyco1_human(display_long)|uniprotkb:FYCO1(gene name)|psi-mi:FYCO1(display_short)|uniprotkb:ZFYVE7(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011532413.1|refseq:XP_006713396.1|refseq:XP_006713397.1|refseq:NP_078789.2|ensembl:ENSG00000163820(gene)|ensembl:ENST00000296137(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR004012(RUN)|interpro:IPR009038(GOLD)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR036598|interpro:IPR037213|interpro:IPR042654|mint:Q9BQS8|rcsb pdb:5CX3|rcsb pdb:5D94|rcsb pdb:7BQI|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|dip:DIP-60600N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:/iOQiItN7ljXD08DN8DvQ1m6t0E9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q9BQQ3 intact:EBI-25475888 intact:EBI-2561458|uniprotkb:Q3SYG7|uniprotkb:Q96H42|uniprotkb:Q8N272|uniprotkb:B3KWC8|ensembl:ENSP00000313869 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gors1_human(display_long)|uniprotkb:GORASP1(gene name)|psi-mi:GORASP1(display_short)|uniprotkb:GOLPH5(gene name synonym)|uniprotkb:GRASP65(gene name synonym)|uniprotkb:Golgi reassembly-stacking protein of 65 kDa(gene name synonym)|uniprotkb:Golgi peripheral membrane protein p65(gene name synonym)|uniprotkb:Golgi phosphoprotein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_114105.1|refseq:NP_001265718.1|refseq:NP_001265719.1|ensembl:ENSG00000114745(gene)|ensembl:ENST00000319283(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:4REY|rcsb pdb:6G8T|rcsb pdb:6G8W|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:gCTXn0H+UPamtVxyvChrMrcQvCA9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q99996 intact:EBI-25475888 intact:EBI-1048311|uniprotkb:O14869|uniprotkb:O43355|uniprotkb:O94895|uniprotkb:Q75N20|uniprotkb:Q9UQH3|uniprotkb:Q9UQQ4|uniprotkb:Q9Y6B8|uniprotkb:A4D1F0|uniprotkb:Q9Y6Y2|uniprotkb:A4D1F2|uniprotkb:A4D1F4|ensembl:ENSP00000348573 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:akap9_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)|uniprotkb:A-kinase anchor protein 450 kDa(gene name synonym)|uniprotkb:A-kinase anchor protein 350 kDa(gene name synonym)|uniprotkb:AKAP 120-like protein(gene name synonym)|uniprotkb:Protein hyperion(gene name synonym)|uniprotkb:Protein yotiao(gene name synonym)|uniprotkb:Centrosome- and Golgi-localized PKN-associated protein(gene name synonym)|uniprotkb:AKAP9(gene name)|psi-mi:AKAP9(display_short)|uniprotkb:AKAP350(gene name synonym)|uniprotkb:AKAP450(gene name synonym)|uniprotkb:KIAA0803(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005742.4|refseq:NP_671714.1|ensembl:ENSG00000127914(gene)|ensembl:ENST00000356239(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044307"(dendritic branch)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR005539(ELK)|interpro:IPR019528|interpro:IPR028745|mint:Q99996|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5576890|reactome:R-HSA-5576893|reactome:R-HSA-5620912|reactome:R-HSA-6802952|reactome:R-HSA-8854518|ensembl:ENSP00000348573|ensembl:ENST00000680766|ensembl:ENSP00000505204|dip:DIP-29942N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:LQUNbTHUgEsjayFEZvczC4e90Nw9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q96SN8 intact:EBI-25475888 intact:EBI-308374|uniprotkb:Q7Z3L4|uniprotkb:Q7Z3U1|uniprotkb:Q7Z7I6|uniprotkb:Q9BSW0|uniprotkb:Q9H6J6|uniprotkb:Q9HCD9|uniprotkb:Q9NV90|uniprotkb:Q9UIW9|uniprotkb:Q5JV18|ensembl:ENSP00000343818 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ck5p2_human(display_long)|uniprotkb:CDK5RAP2(gene name)|psi-mi:CDK5RAP2(display_short)|uniprotkb:KIAA1633(gene name synonym)|uniprotkb:CDK5 activator-binding protein C48(gene name synonym)|uniprotkb:Centrosome-associated protein 215(gene name synonym)|uniprotkb:CEP215(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001011649.1|ensembl:ENSG00000136861(gene)|ensembl:ENST00000349780(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR012943(Spindle associated)|mint:Q96SN8|rcsb pdb:6X0V|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_060719.4|refseq:NP_001258968.1|refseq:XP_006717245.1|dip:DIP-31632N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:/XamYFvD5N/npIkOGnLQkZzmBnU9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q96N16 intact:EBI-25475888 intact:EBI-2680803|uniprotkb:A6H2J5|uniprotkb:A6H2J4|uniprotkb:B8ZZR7|uniprotkb:Q8N7G3|uniprotkb:A6H2J2|uniprotkb:A6H2J3|uniprotkb:Q86Y69|uniprotkb:A8MTK6|intact:EBI-2812508|uniprotkb:D3DVT0|ensembl:ENSP00000282924|ensembl:ENSP00000386925|uniprotkb:B4DHZ8 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:jkip1_human(display_long)|uniprotkb:GABABRBP(gene name synonym)|uniprotkb:JAMIP1(gene name synonym)|uniprotkb:MARLIN1(gene name synonym)|uniprotkb:GABA-B receptor-binding protein(gene name synonym)|uniprotkb:Multiple alpha-helices and RNA-linker protein 1(gene name synonym)|uniprotkb:JAKMIP1(gene name)|psi-mi:JAKMIP1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001293062.1|refseq:NP_001293063.1|refseq:XP_011511702.1|refseq:NP_001092903.1|refseq:NP_653321.1|ensembl:ENSG00000152969(gene)|ensembl:ENST00000282924(transcript)|ensembl:ENST00000409831(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050890"(cognition)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR024836|interpro:IPR031994|mint:Q96N16|refseq:XP_016863282.1 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:tqQJu7pAUKeq6SOKhVJKm2u02mY9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q96CN9 intact:EBI-25475888 intact:EBI-746252|uniprotkb:Q9H6N7|ensembl:ENSP00000318821 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gcc1_human(display_long)|uniprotkb:Golgi coiled-coil protein 1(gene name synonym)|uniprotkb:GCC1(gene name)|psi-mi:GCC1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_078799.2|ensembl:ENSG00000179562(gene)|ensembl:ENST00000321407(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031267"(small GTPase binding)|interpro:IPR000237(GRIP)|reactome:R-HSA-6811440|go:"GO:0000138"(Golgi trans cisterna) - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:SCI+peKjPIvl/HbUUpHGM++qiRE9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q92995 intact:EBI-25475888 intact:EBI-714351|uniprotkb:D3DNS2|uniprotkb:Q96B25|intact:EBI-28978985|ensembl:ENSP00000263966|uniprotkb:A8K2S3|uniprotkb:B4DYF3 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubp13_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 13(gene name synonym)|uniprotkb:Deubiquitinating enzyme 13(gene name synonym)|uniprotkb:Isopeptidase T-3(gene name synonym)|uniprotkb:USP13(gene name)|psi-mi:USP13(display_short)|uniprotkb:ISOT3(gene name synonym)|uniprotkb:Ubiquitin thioesterase 13(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_003931.2|ensembl:ENSG00000058056(gene)|ensembl:ENST00000263966(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044313"(protein K6-linked deubiquitination)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR009060(UBA-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016652(Ubiquitinyl hydrolase)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|interpro:IPR041432|rcsb pdb:2L80|rcsb pdb:2LBC|reactome:R-HSA-5689880|reactome:R-HSA-8948751|ensembl:ENSP00000263966|ensembl:ENST00000496897|ensembl:ENSP00000417146|dip:DIP-53511N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:q6g2QmSYm3Xjoo+tv20s6cN8iHk9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q8TD10 intact:EBI-25475888 intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q8N8E3 intact:EBI-25475888 intact:EBI-2836899|uniprotkb:Q6PIB5|uniprotkb:Q8NCR4|uniprotkb:Q8NFR4|ensembl:ENSP00000442784|ensembl:ENSP00000376522 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ce112_human(display_long)|uniprotkb:CCDC46(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 46(gene name synonym)|uniprotkb:CEP112(gene name)|psi-mi:CEP112(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011522763.1|refseq:NP_001032402.1|refseq:NP_001186094.1|ensembl:ENSG00000154240(gene)|ensembl:ENST00000392769(transcript)|ensembl:ENST00000535342(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097120"(receptor localization to synapse)|interpro:IPR027831 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:iSzC47xD2MFBztjq1zefC+m5bn89606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q8N4C6 intact:EBI-25475888 intact:EBI-1164022|uniprotkb:Q6P0P6|uniprotkb:Q9BWU6|uniprotkb:Q9C012|uniprotkb:Q9C013|uniprotkb:Q9C014|uniprotkb:Q9H5I6|uniprotkb:Q9HAT7|uniprotkb:Q9HBY5|uniprotkb:Q9HCK7|uniprotkb:Q9UH61|uniprotkb:A6NDB8|uniprotkb:B7WPA3|uniprotkb:C9JSB6|uniprotkb:C9JSG2|uniprotkb:C9JXL2|ensembl:ENSP00000371472|uniprotkb:Q5BKU3 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nin_human(display_long)|uniprotkb:Glycogen synthase kinase 3 beta-interacting protein(gene name synonym)|uniprotkb:NIN(gene name)|psi-mi:NIN(display_short)|uniprotkb:KIAA1565(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011535125.1|ensembl:ENSG00000100503(gene)|ensembl:ENST00000382041(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|refseq:NP_057434.4|refseq:NP_065972.3|refseq:NP_891989.2|refseq:NP_891991.1|go:"GO:0005814"(centriole)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019900"(kinase binding)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045177"(apical part of cell)|go:"GO:0048668"(collateral sprouting)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR029664|mint:Q8N4C6|go:"GO:0034454"(microtubule anchoring at centrosome) - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:ZvO0amOxGf+HZIxnXTYCqpnzTjw9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q8N3C7 intact:EBI-25475888 intact:EBI-5655540|uniprotkb:Q96MA5|uniprotkb:Q9H7C0|uniprotkb:B2RMQ3|uniprotkb:A0AV10|uniprotkb:Q7Z4U3|uniprotkb:B7Z7N8|uniprotkb:Q96BR7|ensembl:ENSP00000327009|ensembl:ENSP00000385594 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:clip4_human(display_long)|uniprotkb:RSNL2(gene name synonym)|uniprotkb:Restin-like protein 2(gene name synonym)|uniprotkb:CLIP4(gene name)|psi-mi:CLIP4(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011531411.1|refseq:NP_078968.3|refseq:NP_001274456.1|refseq:NP_001274457.1|refseq:XP_005264619.1|refseq:XP_005264620.1|refseq:XP_006712167.1|refseq:XP_016860447.1|ensembl:ENSG00000115295(gene)|ensembl:ENST00000320081(transcript)|ensembl:ENST00000404424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051010"(microtubule plus-end binding)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028397|interpro:IPR036770|interpro:IPR036859|rcsb pdb:2Z0W - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:aT/vJOx8H2ToHOjl4aQc7lgrSCg9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q8IWJ2 intact:EBI-25475888 intact:EBI-1645320|uniprotkb:O15045|uniprotkb:Q4ZG46|uniprotkb:Q8TDH3|uniprotkb:Q9H2G8|uniprotkb:A6H8X8|intact:EBI-1645335|intact:EBI-28984280|ensembl:ENSP00000307939 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gcc2_human(display_long)|uniprotkb:GCC2(gene name)|psi-mi:GCC2(display_short)|uniprotkb:KIAA0336(gene name synonym)|uniprotkb:RANBP2L4(gene name synonym)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Ran-binding protein 2-like 4(gene name synonym)|uniprotkb:CTCL tumor antigen se1-1(gene name synonym)|uniprotkb:CLL-associated antigen KW-11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-53(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_852118.1|refseq:XP_006712934.1|ensembl:ENSP00000307939|ensembl:ENST00000482325|ensembl:ENSP00000419969|ensembl:ENSG00000135968(gene)|ensembl:ENST00000309863(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0016020"(membrane)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034499"(late endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0070861"(regulation of protein exit from endoplasmic reticulum)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR000237(GRIP)|interpro:IPR032023|rcsb pdb:3BBP|reactome:R-HSA-6811440 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:YeL/V7QABi3DbamH+qE6WfFLAco9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q8IUD2 intact:EBI-25475888 intact:EBI-1044755|uniprotkb:Q6NVK2|uniprotkb:Q8IUD3|uniprotkb:Q8IUD4|uniprotkb:Q8IUD5|uniprotkb:Q8NAS1|uniprotkb:Q9NXN5|uniprotkb:Q9UIK7|uniprotkb:Q9UPS1|intact:EBI-3645200|uniprotkb:A7E295|ensembl:ENSP00000354158|ensembl:ENSP00000468263|uniprotkb:D3DUP7|uniprotkb:D3DUP8|uniprotkb:A2RU77 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rb6i2_human(display_long)|uniprotkb:Rab6-interacting protein 2(gene name synonym)|uniprotkb:ERC1(gene name)|psi-mi:ERC1(display_short)|uniprotkb:ELKS(gene name synonym)|uniprotkb:KIAA1081(gene name synonym)|uniprotkb:RAB6IP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_829883.1|refseq:NP_829884.1|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0015031"(protein transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0007275"(multicellular organism development)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR019018|interpro:IPR019323|interpro:IPR037245|ensembl:ENSG00000082805(gene)|ensembl:ENST00000360905(transcript)|ensembl:ENST00000589028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|refseq:XP_016874553.1|refseq:XP_016874556.1|refseq:XP_011519243.1 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:0W5DM0QbKuWdMW4T+pJKPT7pKgA9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q7Z7A1 intact:EBI-25475888 intact:EBI-2563266|uniprotkb:A2A2Y1|uniprotkb:B2RP67|uniprotkb:Q3MN79|uniprotkb:Q5FWF8|uniprotkb:Q5JVD0|uniprotkb:Q9Y489|uniprotkb:Q8TEP3|uniprotkb:Q6MZR3|uniprotkb:Q6PKC1|intact:EBI-2796138|ensembl:ENSP00000362962 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cntrl_human(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym)|uniprotkb:Centrosomal protein 1(gene name synonym)|uniprotkb:CNTRL(gene name)|psi-mi:CNTRL(display_short)|uniprotkb:CEP110(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_008949.4|ensembl:ENSG00000119397(gene)|ensembl:ENST00000373855(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016020"(membrane)|go:"GO:0035904"(aorta development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0090543"(Flemming body)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR028640|interpro:IPR032675|mint:Q7Z7A1|reactome:R-HSA-1839117|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5655302|reactome:R-HSA-8854518|refseq:XP_005251736.1|refseq:NP_001317691.1|dip:DIP-47280N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:wmPF3eCXN2WiNQIyd0CR3OGJROo9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q76N32 intact:EBI-25475888 intact:EBI-9051024|uniprotkb:B4DRQ1|uniprotkb:D6W5F1|uniprotkb:D6W5F2|uniprotkb:O60326|uniprotkb:Q9BQ18|uniprotkb:Q9UDM9|ensembl:ENSP00000367229 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cep68_human(display_long)|uniprotkb:CEP68(gene name)|psi-mi:CEP68(display_short)|uniprotkb:KIAA0582(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001306029.1|refseq:NP_001306030.1|ensembl:ENST00000260569|ensembl:ENSP00000260569|ensembl:ENSP00000367229|refseq:NP_055962.2|dip:DIP-57845N|go:"GO:0007098"(centrosome cycle)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|interpro:IPR030265|ensembl:ENSG00000011523(gene)|ensembl:ENST00000377990(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol) - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:jSTNLbxpxy/Brk+gJn1SXdZqnj49606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q66GS9 intact:EBI-25475888 intact:EBI-1046993|uniprotkb:O75130|uniprotkb:Q9H8H7|uniprotkb:B2RMY0|uniprotkb:Q58F25|ensembl:ENSP00000257287|intact:EBI-1058323 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cp135_human(display_long)|uniprotkb:Centrosomal protein 4(gene name synonym)|uniprotkb:CEP135(gene name)|psi-mi:CEP135(display_short)|uniprotkb:CEP4(gene name synonym)|uniprotkb:KIAA0635(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_079285.2|rcsb pdb:5FCN|rcsb pdb:5NG4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|ensembl:ENSG00000174799(gene)|ensembl:ENST00000257287(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007099"(centriole replication)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR026732|mint:Q66GS9|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-50271N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:x/sbJVIQUS2zD/l2SQsmV5HwKP89606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q5VU43 intact:EBI-25475888 intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q5VT06 intact:EBI-25475888 intact:EBI-947346|uniprotkb:O75068|uniprotkb:Q8TDK3|uniprotkb:Q8WY20|ensembl:ENSP00000356579 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ce350_human(display_long)|uniprotkb:CEP350(gene name)|psi-mi:CEP350(display_short)|uniprotkb:CAP350(gene name synonym)|uniprotkb:GM133(orf name)|uniprotkb:KIAA0480(gene name synonym)|uniprotkb:Centrosome-associated protein of 350 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_055625.4|dip:DIP-49946N|ensembl:ENSG00000135837(gene)|ensembl:ENST00000367607(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042995"(cell projection)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR025486|interpro:IPR028750|interpro:IPR036859|rcsb pdb:2COZ - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:lwAOfFoQPaS6NHQ1NkmFWBfVA3s9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q14789 intact:EBI-25475888 intact:EBI-709973|uniprotkb:Q14398|uniprotkb:D3DN92|uniprotkb:F1T0J2|uniprotkb:B2ZZ91|uniprotkb:E7EP74|ensembl:ENSP00000341848 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gogb1_human(display_long)|uniprotkb:Giantin(gene name synonym)|uniprotkb:Macrogolgin(gene name synonym)|uniprotkb:372 kDa Golgi complex-associated protein(gene name synonym)|uniprotkb:GOLGB1(gene name)|psi-mi:GOLGB1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_004478.3|refseq:XP_011511001.1|refseq:NP_001243416.1|refseq:NP_001243417.1|refseq:XP_005247428.1|refseq:NP_001243415.1|dip:DIP-34649N|ensembl:ENSG00000173230(gene)|ensembl:ENST00000340645(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1905793"(protein localization to pericentriolar material)|interpro:IPR003106(Leucine zipper, homeobox-associated)|interpro:IPR026202|mint:Q14789|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-9703465 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:suoNOGzPA2FjQsHQs4cdSpqYn/M9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q08379 intact:EBI-25475888 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q08378 intact:EBI-25475888 intact:EBI-355782|uniprotkb:O43241|uniprotkb:Q6P9C7|uniprotkb:Q86XW3|uniprotkb:Q8TDA9|uniprotkb:Q8WZA3|uniprotkb:A5PKX6|intact:EBI-28985028|ensembl:ENSP00000204726|ensembl:ENSP00000410378 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:goga3_human(display_long)|uniprotkb:GOLGA3(gene name)|psi-mi:GOLGA3(display_short)|uniprotkb:Golgin-160(gene name synonym)|uniprotkb:Golgi complex-associated protein of 170 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001166028.1|refseq:NP_005886.2|ensembl:ENSP00000204726|ensembl:ENSP00000410378|ensembl:ENST00000456883|ensembl:ENSP00000409303|ensembl:ENST00000545875|ensembl:ENSP00000442603|ensembl:ENSG00000090615(gene)|ensembl:ENST00000204726(transcript)|ensembl:ENST00000450791(transcript)|go:"GO:0045296"(cadherin binding)|go:"GO:0090498"(extrinsic component of Golgi membrane)|interpro:IPR033288|mint:Q08378|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9696270|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|refseq:XP_006719799.1|refseq:XP_006719800.1 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:7AjSzX3sUzfKpZkvdKDM0L//zYM9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q08117 intact:EBI-25475888 intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|uniprotkb:B2RBL0|uniprotkb:Q14CJ1|ensembl:ENSP00000317537 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001121.2|refseq:NP_945320.1|refseq:NP_945321.1|ensembl:ENSG00000104964(gene)|ensembl:ENST00000327141(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|go:"GO:0032091"(negative regulation of protein binding) - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q04726 intact:EBI-25475888 intact:EBI-1052057|uniprotkb:Q8IVV6|uniprotkb:Q8WVR2|uniprotkb:Q9HCM5|uniprotkb:B4DPT0|uniprotkb:F8W964|uniprotkb:E9PD64|ensembl:ENSP00000452871|uniprotkb:Q6PI57 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tle3_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 3(gene name synonym)|uniprotkb:TLE3(gene name)|psi-mi:TLE3(display_short)|uniprotkb:KIAA1547(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001098662.1|refseq:NP_005069.2|refseq:NP_065959.1|refseq:NP_001269908.1|refseq:NP_001269909.1|refseq:NP_001269910.1|refseq:NP_001269911.1|ensembl:ENSG00000140332(gene)|ensembl:ENST00000558939(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q04726|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|reactome:R-HSA-9018519|dip:DIP-36666N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:lbsBYgdnyUWioqJ5euhotXA84Xg9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q04724 intact:EBI-25475888 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:P49454 intact:EBI-25475888 intact:EBI-968343|ensembl:ENSP00000355922|uniprotkb:Q13171|uniprotkb:Q13246|uniprotkb:Q5VVM7|intact:EBI-2563723|intact:EBI-21028103 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cenpf_human(display_long)|uniprotkb:CENPF(gene name)|psi-mi:CENPF(display_short)|uniprotkb:Kinetochore protein CENPF(gene name synonym)|uniprotkb:Mitosin(gene name synonym)|uniprotkb:AH antigen(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000117724(gene)|ensembl:ENST00000366955(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0001822"(kidney development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021591"(ventricular system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0042493"|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR018302|interpro:IPR018463|interpro:IPR019513|interpro:IPR043513|mint:P49454|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-156711|refseq:NP_057427.3|refseq:XP_016855575.1 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:gPlJiOCF1/MAVT80oKwlQlLgluo9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:P35241 intact:EBI-25475888 intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:75lzbINdL0deHtiWY7IwioSh5749606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:P31323 intact:EBI-25475888 intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:P13861 intact:EBI-25475888 intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:O95684 intact:EBI-25475888 intact:EBI-1266334|uniprotkb:Q49AI0|uniprotkb:Q5R3F6|uniprotkb:Q96EW1|uniprotkb:A8K1D1|uniprotkb:B2R705|ensembl:ENSP00000355812 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cep43_human(display_long)|uniprotkb:CEP43(gene name)|psi-mi:CEP43(display_short)|uniprotkb:FGFR1 oncogene partner(gene name synonym)|uniprotkb:FGFR1OP(gene name synonym)|uniprotkb:FOP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_008976.1|refseq:NP_919410.1|ensembl:ENSG00000213066(gene)|ensembl:ENST00000366847(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR018993|rcsb pdb:2D68|reactome:R-HSA-1839117|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5655302|reactome:R-HSA-8854518 - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:AcqOicx3UulQVfNzo6X0XyfExcc9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:O95613 intact:EBI-25475888 intact:EBI-530012|uniprotkb:O43152|uniprotkb:Q7Z7C9|intact:EBI-28971202|ensembl:ENSP00000352572 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pcnt_human(display_long)|uniprotkb:Pericentrin-B(gene name synonym)|uniprotkb:Kendrin(gene name synonym)|uniprotkb:PCNT(gene name)|psi-mi:PCNT(display_short)|uniprotkb:KIAA0402(gene name synonym)|uniprotkb:PCNT2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000352572|refseq:NP_006022.3|refseq:NP_001302458.1|ensembl:ENSG00000160299(gene)|ensembl:ENST00000359568(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR019528|interpro:IPR028745|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|dip:DIP-33829N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:8YHnOQE3b77ocsel2oAdsqvE+js9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:O75506 intact:EBI-25475888 intact:EBI-748664|uniprotkb:Q7Z5Z3|uniprotkb:Q53XA8|ensembl:ENSP00000392896|ensembl:ENSP00000458007 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hsbp1_human(display_long)|uniprotkb:Nasopharyngeal carcinoma-associated antigen 13(gene name synonym)|uniprotkb:HSBP1(gene name)|psi-mi:HSBP1(display_short)|uniprotkb:HSF1BP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001528.1|interpro:IPR009643(Heat shock factor binding 1)|rcsb pdb:3CI9|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|ensembl:ENSG00000230989(gene)|ensembl:ENST00000433866(transcript)|ensembl:ENST00000570259(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0070370"(cellular heat acclimation) - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:3JML7OxHIw8M91ARKPfOhJ9kVbk9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:Q4V328 intact:EBI-25475888 intact:EBI-717919|uniprotkb:A6NL78|uniprotkb:Q3MJ75|uniprotkb:Q4V327|uniprotkb:Q4V330|uniprotkb:Q5HYG1|uniprotkb:Q6N046|uniprotkb:Q96DH8|uniprotkb:Q9NQ43|uniprotkb:Q9ULQ3|ensembl:ENSP00000365606 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:grap1_human(display_long)|uniprotkb:GRIPAP1(gene name)|psi-mi:GRIPAP1(display_short)|uniprotkb:KIAA1167(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_064522.3|ensembl:ENSG00000068400(gene)|ensembl:ENST00000376423(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072562"(blood microparticle)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q4V328|dip:DIP-47299N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:iIGfz5XvbexX4taRlMqWYsfAVBo9606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449630 uniprotkb:A7MCY6 intact:EBI-25475888 intact:EBI-359969|uniprotkb:Q14DW3|uniprotkb:O94873|uniprotkb:B2RZG6|ensembl:ENSP00000354777 psi-mi:p0dtd1-pro_0000449630(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tbkb1_human(display_long)|uniprotkb:TBKBP1(gene name)|psi-mi:TBKBP1(display_short)|uniprotkb:SINTBAD(gene name synonym)|uniprotkb:KIAA0775(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375436|imex:IM-28441-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_055541.1|ensembl:ENSG00000198933(gene)|ensembl:ENST00000361722(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR024581|interpro:IPR041641|mint:A7MCY6|refseq:XP_005257916.1|refseq:XP_005257917.1|refseq:XP_005257918.1|refseq:XP_005257919.1|dip:DIP-27604N - chain-seq-start:5325|chain-seq-end:5925 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:F98KM8XJ6ElyhUel43fFsarYA3g2697049 rogid:Hf7hEVRztbT681BKO7sMjh1EwX09606 rigid:Yu0unKryRek1uc3nGfMobFoOdl4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449631 uniprotkb:Q9NXA8 intact:EBI-25475920 intact:EBI-6556144|uniprotkb:B4DFM4|uniprotkb:B4DYJ5|uniprotkb:F5H5Z9|uniprotkb:Q5T294|uniprotkb:Q5T295|uniprotkb:Q9Y6E6|ensembl:ENSP00000380509|ensembl:ENSP00000476228|ensembl:ENSP00000505086|ensembl:ENSP00000505496 psi-mi:p0dtd1-pro_0000449631(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sir5_human(display_long)|uniprotkb:SIRT5(gene name)|psi-mi:SIRT5(display_short)|uniprotkb:SIR2L5(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 5(gene name synonym)|uniprotkb:SIR2-like protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375485|imex:IM-28441-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001180196.1|refseq:NP_001229756.1|refseq:NP_036373.1|refseq:NP_112534.1|refseq:XP_005249025.1|ensembl:ENSG00000124523(gene)|ensembl:ENST00000397350(transcript)|ensembl:ENST00000606117(transcript)|ensembl:ENST00000680151(transcript)|ensembl:ENST00000680432(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010566"(regulation of ketone biosynthetic process)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0036046"(protein demalonylation)|go:"GO:0036047"(peptidyl-lysine demalonylation)|go:"GO:0036048"(protein desuccinylation)|go:"GO:0036049"(peptidyl-lysine desuccinylation)|go:"GO:0036054"(protein-malonyllysine demalonylase activity)|go:"GO:0036055"(protein-succinyllysine desuccinylase activity)|go:"GO:0061697"(protein-glutaryllysine deglutarylase activity)|go:"GO:0061698"(protein deglutarylation)|go:"GO:0070403"(NAD+ binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR027546|interpro:IPR029035|rcsb pdb:2B4Y|rcsb pdb:2NYR|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4G1C|rcsb pdb:4HDA|rcsb pdb:5BWL|rcsb pdb:5XHS|rcsb pdb:6ACE|rcsb pdb:6ACL|rcsb pdb:6ACO|rcsb pdb:6ACP|rcsb pdb:6EQS|rcsb pdb:6LJK|rcsb pdb:6LJM|rcsb pdb:6LJN|reactome:R-HSA-2151201 - chain-seq-start:5926|chain-seq-end:6452 - figure legend:Table 2, no 10|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:LpGB5BQU5uhWK/60422jkiKHRL82697049 rogid:w8a5w8pZghQpNpbgYCsuPIj+Sgo9606 rigid:Nl3d+AS8fzxK2E/kyQsWX4EzUt8 false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449631 uniprotkb:P12268 intact:EBI-25475920 intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584 psi-mi:p0dtd1-pro_0000449631(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375485|imex:IM-28441-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191 - chain-seq-start:5926|chain-seq-end:6452 - figure legend:Table 2, no 10|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:LpGB5BQU5uhWK/60422jkiKHRL82697049 rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606 rigid:Nl3d+AS8fzxK2E/kyQsWX4EzUt8 false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449631 uniprotkb:P06280 intact:EBI-25475920 intact:EBI-2513305|ensembl:ENSP00000218516|uniprotkb:Q6LER7 psi-mi:p0dtd1-pro_0000449631(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:agal_human(display_long)|uniprotkb:GLA(gene name)|psi-mi:GLA(display_short)|uniprotkb:Alpha-D-galactoside galactohydrolase(gene name synonym)|uniprotkb:Alpha-D-galactosidase A(gene name synonym)|uniprotkb:Melibiase(gene name synonym)|uniprotkb:Galactosylgalactosylglucosylceramidase GLA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375485|imex:IM-28441-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) reactome:R-HSA-1660662|reactome:R-HSA-6798695|ensembl:ENSG00000102393(gene)|ensembl:ENST00000218516(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004557"(alpha-galactosidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016936"(galactoside binding)|go:"GO:0017041"(galactosylgalactosylglucosylceramidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046477"(glycosylceramide catabolic process)|go:"GO:0046479"(glycosphingolipid catabolic process)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0052692"(raffinose alpha-galactosidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000111(Glycoside hydrolase, clan GH-D)|interpro:IPR002241(Glycoside hydrolase, family 27)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR035373|rcsb pdb:1R46|rcsb pdb:1R47|rcsb pdb:3GXN|rcsb pdb:3GXP|rcsb pdb:3GXT|rcsb pdb:3HG2|rcsb pdb:3HG3|rcsb pdb:3HG4|rcsb pdb:3HG5|rcsb pdb:3LX9|rcsb pdb:3LXA|rcsb pdb:3LXB|rcsb pdb:3LXC|rcsb pdb:3S5Y|rcsb pdb:3S5Z|rcsb pdb:3TV8|rcsb pdb:4NXS|rcsb pdb:6IBK|rcsb pdb:6IBM|rcsb pdb:6IBR|rcsb pdb:6IBT|refseq:NP_000160.1 - chain-seq-start:5926|chain-seq-end:6452 - figure legend:Table 2, no 10|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:LpGB5BQU5uhWK/60422jkiKHRL82697049 rogid:en4+xuRp2k6kcAkvM2Bla9N3+189606 rigid:Nl3d+AS8fzxK2E/kyQsWX4EzUt8 false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449632 uniprotkb:Q9H4P4 intact:EBI-25475891 intact:EBI-2130266|uniprotkb:B2RBT8|uniprotkb:O75598|intact:EBI-2563208|intact:EBI-11576203|uniprotkb:A6NFW0|ensembl:ENSP00000342755|ensembl:ENSP00000447303|ensembl:ENSP00000484671 psi-mi:p0dtd1-pro_0000449632(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rnf41_human(display_long)|uniprotkb:RNF41(gene name)|psi-mi:RNF41(display_short)|uniprotkb:FLRF(gene name synonym)|uniprotkb:NRDP1(gene name synonym)|uniprotkb:RING finger protein 41(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NRDP1(gene name synonym)|uniprotkb:SBBI03(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375495|imex:IM-28441-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011536036.1|refseq:XP_011536037.1|refseq:NP_001229755.1|refseq:NP_005776.1|refseq:NP_919340.1|refseq:NP_919339.1|refseq:XP_005268618.1|ensembl:ENSG00000181852(gene)|ensembl:ENST00000345093(transcript)|ensembl:ENST00000552656(transcript)|ensembl:ENST00000615206(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015036(USP8 interacting)|interpro:IPR017907|interpro:IPR037255|rcsb pdb:2FZP|rcsb pdb:2GWF|reactome:R-HSA-1358803|reactome:R-HSA-983168 - chain-seq-start:6453|chain-seq-end:6798 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:LMNsirx/ZGBUQRB+wttvWN3+IXs2697049 rogid:jthVZwxUECSdqeJ2jZQ5UL28kDY9606 rigid:aYuGH/Eso3ONOnEJ+VB8iewtAr4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449632 uniprotkb:P62330 intact:EBI-25475891 intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2 psi-mi:p0dtd1-pro_0000449632(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375495|imex:IM-28441-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N - chain-seq-start:6453|chain-seq-end:6798 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:LMNsirx/ZGBUQRB+wttvWN3+IXs2697049 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606 rigid:aYuGH/Eso3ONOnEJ+VB8iewtAr4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449632 uniprotkb:P61970 intact:EBI-25475891 intact:EBI-591778|uniprotkb:P13662|uniprotkb:Q6IB67|uniprotkb:B2R4G7|ensembl:ENSP00000219169|ensembl:ENSP00000457022|ensembl:ENSP00000457989 psi-mi:p0dtd1-pro_0000449632(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ntf2_human(display_long)|uniprotkb:Placental protein 15(gene name synonym)|uniprotkb:NUTF2(gene name)|psi-mi:NUTF2(display_short)|uniprotkb:NTF2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375495|imex:IM-28441-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005787.1|refseq:NP_001308967.1|refseq:NP_001308968.1|refseq:NP_001308969.1|refseq:NP_001308970.1|dip:DIP-6057N|ensembl:ENSG00000102898(gene)|ensembl:ENST00000219169(transcript)|ensembl:ENST00000568396(transcript)|ensembl:ENST00000569436(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0051028"(mRNA transport)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR018222|interpro:IPR032710|rcsb pdb:1GY5 - chain-seq-start:6453|chain-seq-end:6798 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:LMNsirx/ZGBUQRB+wttvWN3+IXs2697049 rogid:hDy30rHCK1a4LjUfAWtf1DEu8n89606 rigid:aYuGH/Eso3ONOnEJ+VB8iewtAr4 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9H0H0 intact:EBI-25492395 intact:EBI-8471507|uniprotkb:Q9ULD3|intact:MINT-4712719|ensembl:ENSP00000414237|ensembl:ENSP00000482710 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:int2_human(display_long)|uniprotkb:INTS2(gene name)|psi-mi:INTS2(display_short)|uniprotkb:KIAA1287(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001317346.1|dip:DIP-48477N|refseq:NP_065799.1|ensembl:ENSG00000108506(gene)|ensembl:ENST00000444766(transcript)|ensembl:ENST00000617492(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR026236|interpro:IPR029321|mint:Q9H0H0|rcsb pdb:7CUN|reactome:R-HSA-6807505|go:"GO:0016180"(snRNA processing) - chain-seq-start:6799|chain-seq-end:7096 function:"Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes"|comment:mint|comment:homomint figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:kbczUMPyLBZtWLKxKPd5DHI35zc9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9BVQ7 intact:EBI-25492395 intact:EBI-7950854|uniprotkb:Q9HA41|intact:MINT-4718214|uniprotkb:Q9H8W7|uniprotkb:C9JHR5|ensembl:ENSP00000305494 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:spa5l_human(display_long)|uniprotkb:SPATA5L1(gene name)|psi-mi:SPATA5L1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_076968.2|refseq:NP_001310569.1|ensembl:ENSG00000171763(gene)|ensembl:ENST00000305560(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|mint:Q9BVQ7 - chain-seq-start:6799|chain-seq-end:7096 comment:mint|comment:homomint figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:8FTQdkGYS4xx3pmJDk9xNtPy3Ao9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:O75564 intact:EBI-25492395 intact:EBI-8607681|intact:MINT-8176614|uniprotkb:O75565|intact:EBI-12040229|uniprotkb:D3DWI5|uniprotkb:Q86XJ5|ensembl:ENSP00000461610|ensembl:ENSP00000483808 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:jerky_human(display_long)|uniprotkb:JRK(gene name)|psi-mi:JRK(display_short)|uniprotkb:JH8(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001070995.2|refseq:NP_001266281.1|refseq:NP_003715.3|refseq:XP_006716740.1|refseq:XP_006716741.1|refseq:XP_011515656.1|ensembl:ENSG00000234616(gene)|ensembl:ENST00000571961(transcript)|ensembl:ENST00000615982(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like) - chain-seq-start:6799|chain-seq-end:7096 comment:mint|comment:homomint figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:UOnRaBYBfmixB5Ir7x9GOCL+Lss9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:O14972 intact:EBI-25492395 intact:EBI-7207091|uniprotkb:B7Z6B1|uniprotkb:Q2TAY6|uniprotkb:B2R6T8|uniprotkb:D3DSH4|intact:MINT-8247532|ensembl:ENSP00000311399 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vp26c_human(display_long)|uniprotkb:VPS26C(gene name)|psi-mi:VPS26C(display_short)|uniprotkb:DCRA(gene name synonym)|uniprotkb:DSCR3(gene name synonym)|uniprotkb:DSCRA(gene name synonym)|uniprotkb:Down syndrome critical region protein 3(gene name synonym)|uniprotkb:Down syndrome critical region protein A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_006043.1|ensembl:ENSG00000157538(gene)|ensembl:ENST00000309117(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0032456"(endocytic recycling)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR028934|mint:O14972|refseq:NP_001317947.1|refseq:NP_001317951.1|dip:DIP-47317N - chain-seq-start:6799|chain-seq-end:7096 comment:mint|comment:homomint figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:MVLg5uPQKNhYslttvf3JnGduv5Q9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q96LT9 intact:EBI-25492395 intact:EBI-2602807|uniprotkb:Q96FK7|uniprotkb:Q96JI8|uniprotkb:Q9NXX2|uniprotkb:Q5TZ87|uniprotkb:Q9NSU7|uniprotkb:D3DT74|intact:EBI-28982482|ensembl:ENSP00000391432|ensembl:ENSP00000432886|uniprotkb:A8K1C9 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rnpc3_human(display_long)|uniprotkb:RNPC3(gene name)|psi-mi:RNPC3(display_short)|uniprotkb:KIAA1839(gene name synonym)|uniprotkb:RBM40(gene name synonym)|uniprotkb:RNP(gene name synonym)|uniprotkb:RNA-binding motif protein 40(gene name synonym)|uniprotkb:U11/U12 small nuclear ribonucleoprotein 65 kDa protein(gene name synonym)|uniprotkb:SNRNP65(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_060089.1|ensembl:ENSP00000391432|ensembl:ENST00000524631|ensembl:ENSP00000437278|ensembl:ENSP00000432886|ensembl:ENSG00000185946(gene)|ensembl:ENST00000423855(transcript)|ensembl:ENST00000533099(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0030626"(U12 snRNA binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034147|interpro:IPR035979|rcsb pdb:3EGN|rcsb pdb:5OBN|reactome:R-HSA-72165 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:ehmZe1svzkhcslvywgnQ2MmcPD09606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:A7MCY6 intact:EBI-25492395 intact:EBI-359969|uniprotkb:Q14DW3|uniprotkb:O94873|uniprotkb:B2RZG6|ensembl:ENSP00000354777 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tbkb1_human(display_long)|uniprotkb:TBKBP1(gene name)|psi-mi:TBKBP1(display_short)|uniprotkb:SINTBAD(gene name synonym)|uniprotkb:KIAA0775(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_055541.1|ensembl:ENSG00000198933(gene)|ensembl:ENST00000361722(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR024581|interpro:IPR041641|mint:A7MCY6|refseq:XP_005257916.1|refseq:XP_005257917.1|refseq:XP_005257918.1|refseq:XP_005257919.1|dip:DIP-27604N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:Hf7hEVRztbT681BKO7sMjh1EwX09606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9Y6G5 intact:EBI-25492395 intact:EBI-1550310|uniprotkb:Q9P077|uniprotkb:D3DT07|ensembl:ENSP00000274458 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:comda_human(display_long)|uniprotkb:COMMD10(gene name)|psi-mi:COMMD10(display_short)|uniprotkb:HSPC305(orf name)|uniprotkb:PTD002(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_057228.1|refseq:NP_001295009.1|ensembl:ENSG00000145781(gene)|ensembl:ENST00000274458(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR017920|interpro:IPR037361|mint:Q9Y6G5|reactome:R-HSA-8951664 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:yRozKabxLJMAEbM9QfLGOQCzRxE9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9Y2K2 intact:EBI-25492395 intact:EBI-1181460|intact:EBI-1384133|uniprotkb:Q59FY2|uniprotkb:Q5M9N1|uniprotkb:Q6P3R6|uniprotkb:Q8IYM8|uniprotkb:Q9HA50|uniprotkb:H0Y494|uniprotkb:J3KPC8|ensembl:ENSP00000364449|uniprotkb:A1A5A8 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sik3_human(display_long)|uniprotkb:QSK(gene name synonym)|uniprotkb:KIAA0999(gene name synonym)|uniprotkb:SIK3(gene name)|psi-mi:SIK3(display_short)|uniprotkb:Salt-inducible kinase 3(gene name synonym)|uniprotkb:L19(orf name)|uniprotkb:Serine/threonine-protein kinase QSK(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_079440.3|ensembl:ENSG00000160584(gene)|ensembl:ENST00000375300(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034672|refseq:NP_001268678.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:YZTDZCOcd7R9N57N7J/iFkCxzwo9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9Y2D8 intact:EBI-25492395 intact:EBI-2212028|uniprotkb:B4DFE3|uniprotkb:J3KR02|uniprotkb:A8K8W0|uniprotkb:D3DT13|uniprotkb:Q6P2P8|uniprotkb:Q6ULS1|uniprotkb:Q7L168|uniprotkb:Q9UIX0|intact:EBI-10964529|ensembl:ENSP00000340279 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:adip_human(display_long)|uniprotkb:SSX2IP(gene name)|psi-mi:SSX2IP(display_short)|uniprotkb:KIAA0923(gene name synonym)|uniprotkb:Afadin DIL domain-interacting protein(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011538912.1|refseq:NP_001159765.1|refseq:NP_001159766.1|refseq:NP_001159767.1|refseq:NP_001159889.1|refseq:NP_054740.3|refseq:XP_005270484.1|refseq:XP_005270485.1|refseq:XP_006710394.1|refseq:XP_016855723.1|ensembl:ENSG00000117155(gene)|ensembl:ENST00000342203(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR021622|mint:Q9Y2D8 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:E0VeMRF9SrpQKSJFP01XEbMjeF89606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9UN81 intact:EBI-25492395 intact:EBI-722458|intact:EBI-8874490|uniprotkb:Q15605 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lorf1_human(display_long)|uniprotkb:L1RE1(gene name)|psi-mi:L1RE1(display_short)|uniprotkb:LINE retrotransposable element 1(gene name synonym)|uniprotkb:LINE1 retrotransposable element 1(gene name synonym)|uniprotkb:LRE1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) dip:DIP-48676N|go:"GO:0000166"(nucleotide binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032197"(transposition, RNA-mediated)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004244(Transposase, L1)|interpro:IPR035300|interpro:IPR035301|interpro:IPR042566|interpro:IPR043636|rcsb pdb:2LDY|rcsb pdb:2W7A|rcsb pdb:2YKO|rcsb pdb:2YKP|rcsb pdb:2YKQ|rcsb pdb:6FIA - chain-seq-start:6799|chain-seq-end:7096 caution:This sequence has been withdrawn from Uniprot.|crc64:C9ED80C33ED37523 figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:pefRokDO38574Jo5bl2/49LYvaQ9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9UKF6 intact:EBI-25492395 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9UHP3 intact:EBI-25492395 intact:EBI-2513462|ensembl:ENSP00000285679|uniprotkb:Q9H9W1|uniprotkb:Q6DHZ9|uniprotkb:C0LSZ0 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubp25_human(display_long)|uniprotkb:USP25(gene name)|psi-mi:USP25(display_short)|uniprotkb:USP21(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 25(gene name synonym)|uniprotkb:Deubiquitinating enzyme 25(gene name synonym)|uniprotkb:USP on chromosome 21(gene name synonym)|uniprotkb:Ubiquitin thioesterase 25(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000155313(gene)|ensembl:ENST00000285679(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019783"(ubiquitin-like protein-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1904293"(negative regulation of ERAD pathway)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR009060(UBA-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:2MUX|rcsb pdb:5GP7|rcsb pdb:5O71|rcsb pdb:6H4J|rcsb pdb:6H4K|rcsb pdb:6HEL|rcsb pdb:6HEM|reactome:R-HSA-5689880|refseq:NP_001269970.1|refseq:NP_001269971.1|refseq:NP_037528.3 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:PNngYJUduwx8fZiU1uDhAWYeZz49606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9UHD2 intact:EBI-25492395 intact:EBI-356402|intact:EBI-5773956|intact:EBI-1383470|uniprotkb:Q8IYV3|uniprotkb:Q9NUJ5|ensembl:ENSP00000329967|ensembl:ENSP00000498995|uniprotkb:A8K4S4 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tbk1_human(display_long)|uniprotkb:TBK1(gene name)|psi-mi:TBK1(display_short)|uniprotkb:NAK(gene name synonym)|uniprotkb:TANK-binding kinase 1(gene name synonym)|uniprotkb:T2K(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_037386.1|go:"GO:0004672"(protein kinase activity)|ensembl:ENSG00000183735(gene)|ensembl:ENST00000331710(transcript)|ensembl:ENST00000650790(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901214"(regulation of neuron death)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR041087|interpro:IPR041309|mint:Q9UHD2|rcsb pdb:4EFO|rcsb pdb:4EUT|rcsb pdb:4EUU|rcsb pdb:4IM0|rcsb pdb:4IM2|rcsb pdb:4IM3|rcsb pdb:4IW0|rcsb pdb:4IWO|rcsb pdb:4IWP|rcsb pdb:4IWQ|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:5EP6|rcsb pdb:5W5V|rcsb pdb:6BNY|rcsb pdb:6BOD|rcsb pdb:6BOE|rcsb pdb:6CQ0|rcsb pdb:6CQ4|rcsb pdb:6CQ5|rcsb pdb:6NT9|rcsb pdb:6O8B|rcsb pdb:6RSR|rcsb pdb:6RST|rcsb pdb:6RSU|reactome:R-HSA-1606341|reactome:R-HSA-168928|reactome:R-HSA-3134975|reactome:R-HSA-3249367|reactome:R-HSA-3270619|reactome:R-HSA-9008059|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-9679191|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|refseq:XP_005268866.1|refseq:XP_005268867.1|dip:DIP-27529N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:Cf+RbPJBZTpm7XIqbAD2OEC6VEs9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9UBI1 intact:EBI-25492395 intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen) - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9P2S5 intact:EBI-25492395 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9P2D0 intact:EBI-25492395 intact:EBI-1052017|uniprotkb:Q2QKU2|uniprotkb:Q2QKU3|uniprotkb:Q2QKU4|uniprotkb:Q5TFD7|uniprotkb:Q5TFD9|uniprotkb:Q8IUQ9|uniprotkb:Q8IUY7|uniprotkb:Q8TAI4|uniprotkb:Q9HBI8|uniprotkb:Q9Y3T8|ensembl:ENSP00000305721|ensembl:ENSP00000489389 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ibtk_human(display_long)|uniprotkb:IBTK(gene name)|psi-mi:IBTK(display_short)|uniprotkb:BTKI(gene name synonym)|uniprotkb:KIAA1417(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_056340.2|refseq:NP_001287835.1|ensembl:ENSG00000005700(gene)|ensembl:ENSG00000283068(gene)|ensembl:ENST00000306270(transcript)|ensembl:ENST00000635454(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR002110(Ankyrin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR020683|interpro:IPR036770 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:cP+4mOtwZi3q2AjApgwpcJRpJ6M9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9P000 intact:EBI-25492395 intact:EBI-1550510|uniprotkb:Q9H0R0|uniprotkb:Q96FI2|uniprotkb:E9PAN2|ensembl:ENSP00000263401 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:comd9_human(display_long)|uniprotkb:COMMD9(gene name)|psi-mi:COMMD9(display_short)|uniprotkb:HSPC166(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_054905.2|refseq:NP_001294866.1|ensembl:ENSG00000110442(gene)|ensembl:ENST00000263401(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006814"(sodium ion transport)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR017920|interpro:IPR037360|rcsb pdb:4NKN|rcsb pdb:4OE9|rcsb pdb:6BP6|reactome:R-HSA-6798695|reactome:R-HSA-8951664 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:2MhNQZU+OGXGZ2nuSi1AS8+bpz09606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9NX08 intact:EBI-25492395 intact:EBI-725694|uniprotkb:Q8WUR4|uniprotkb:Q9HC15|ensembl:ENSP00000370984 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:comd8_human(display_long)|uniprotkb:COMMD8(gene name)|psi-mi:COMMD8(display_short)|uniprotkb:MDS022(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_060315.1|ensembl:ENSG00000169019(gene)|ensembl:ENST00000381571(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR017920|mint:Q9NX08|reactome:R-HSA-8951664|refseq:NP_001316597.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:m3HKrdrtTRNJyCfMBLOZCaZRexg9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9NVH2 intact:EBI-25492395 intact:EBI-11276282|uniprotkb:B4DLZ6|uniprotkb:B7WNP6|uniprotkb:B7WPB6|uniprotkb:Q8N4K7|uniprotkb:Q8WUH5|uniprotkb:Q9H9V3|uniprotkb:Q9NVU5|uniprotkb:Q9UFC6|uniprotkb:Q9UFM3|ensembl:ENSP00000355961 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:int7_human(display_long)|uniprotkb:INTS7(gene name)|psi-mi:INTS7(display_short)|uniprotkb:C1orf73(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001186738.1|refseq:NP_001186740.1|refseq:NP_001186741.1|refseq:NP_056249.1|ensembl:ENSG00000143493(gene)|ensembl:ENST00000366994(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033060|mint:Q9NVH2|rcsb pdb:7CUN|reactome:R-HSA-6807505 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:PqhjJZUeAkdQHmckoWrwfsPUUeI9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9H4B6 intact:EBI-25492395 intact:EBI-1017775|uniprotkb:Q6IA58|uniprotkb:Q9H949|uniprotkb:Q9HAK9|uniprotkb:A8K4B8|uniprotkb:D3DSB6|ensembl:ENSP00000324729 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sav1_human(display_long)|uniprotkb:SAV1(gene name)|psi-mi:SAV1(display_short)|uniprotkb:WW45(gene name synonym)|uniprotkb:45 kDa WW domain protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_068590.1|ensembl:ENSG00000151748(gene)|ensembl:ENST00000324679(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0035329"(hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|mint:Q9H4B6|rcsb pdb:6AO5|reactome:R-HSA-2028269|dip:DIP-36127N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:djvNX49LV19MDK/wNLfLkX2JMxM9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9H000 intact:EBI-25492395 intact:EBI-2341005|uniprotkb:A6NIA2|uniprotkb:Q9BUY2|uniprotkb:B3KRC5|uniprotkb:Q96BD4|uniprotkb:Q8N391|uniprotkb:Q9NRY1|uniprotkb:B4DPR4|intact:EBI-11126681|ensembl:ENSP00000170447|ensembl:ENSP00000502893 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mkrn2_human(display_long)|uniprotkb:MKRN2(gene name)|psi-mi:MKRN2(display_short)|uniprotkb:RNF62(gene name synonym)|uniprotkb:RING finger protein 62(gene name synonym)|uniprotkb:HSPC070(orf name)|uniprotkb:RING-type E3 ubiquitin transferase makorin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_054879.3|refseq:NP_001258636.1|ensembl:ENSG00000075975(gene)|ensembl:ENST00000170447(transcript)|ensembl:ENST00000677816(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR026293|interpro:IPR036855|interpro:IPR041367|mint:Q9H000 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:ZI7Jr4Fd52sQnfeNXXcZ0NscyD89606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q9GZQ3 intact:EBI-25492395 intact:EBI-1550256|uniprotkb:Q9NVN6|uniprotkb:Q9UHX5|uniprotkb:D3DWN7|ensembl:ENSP00000304544|ensembl:ENSP00000385793|ensembl:ENSP00000394331|ensembl:ENSP00000445840 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:comd5_human(display_long)|uniprotkb:COMMD5(gene name)|psi-mi:COMMD5(display_short)|uniprotkb:HT002(orf name)|uniprotkb:Hypertension-related calcium-regulated gene protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001274166.1|refseq:NP_001074472.1|refseq:NP_001074473.1|refseq:NP_054785.2|ensembl:ENSG00000170619(gene)|ensembl:ENST00000305103(transcript)|ensembl:ENST00000402718(transcript)|ensembl:ENST00000450361(transcript)|ensembl:ENST00000543949(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR017920|interpro:IPR037357|reactome:R-HSA-8951664 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:twwnNUW5VEZumbVyPVv9WAIwvgQ9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q96II8 intact:EBI-25492395 intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q96HP0 intact:EBI-25492395 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q8TEM1 intact:EBI-25492395 intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q8N668 intact:EBI-25492395 intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q8IUD2 intact:EBI-25492395 intact:EBI-1044755|uniprotkb:Q6NVK2|uniprotkb:Q8IUD3|uniprotkb:Q8IUD4|uniprotkb:Q8IUD5|uniprotkb:Q8NAS1|uniprotkb:Q9NXN5|uniprotkb:Q9UIK7|uniprotkb:Q9UPS1|intact:EBI-3645200|uniprotkb:A7E295|ensembl:ENSP00000354158|ensembl:ENSP00000468263|uniprotkb:D3DUP7|uniprotkb:D3DUP8|uniprotkb:A2RU77 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rb6i2_human(display_long)|uniprotkb:Rab6-interacting protein 2(gene name synonym)|uniprotkb:ERC1(gene name)|psi-mi:ERC1(display_short)|uniprotkb:ELKS(gene name synonym)|uniprotkb:KIAA1081(gene name synonym)|uniprotkb:RAB6IP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_829883.1|refseq:NP_829884.1|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0015031"(protein transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0007275"(multicellular organism development)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR019018|interpro:IPR019323|interpro:IPR037245|ensembl:ENSG00000082805(gene)|ensembl:ENST00000360905(transcript)|ensembl:ENST00000589028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|refseq:XP_016874553.1|refseq:XP_016874556.1|refseq:XP_011519243.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:0W5DM0QbKuWdMW4T+pJKPT7pKgA9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q86X10 intact:EBI-25492395 intact:EBI-1755842|uniprotkb:A2A2E8|uniprotkb:Q5TG31|uniprotkb:Q8N3D1|uniprotkb:Q8WWC0|uniprotkb:Q9H3X8|uniprotkb:Q9UJR1|uniprotkb:Q9ULK1|uniprotkb:Q9Y3G9|uniprotkb:A2A2E9|ensembl:ENSP00000262879|ensembl:ENSP00000380233 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rlgpb_human(display_long)|uniprotkb:RALGAPB(gene name)|psi-mi:RALGAPB(display_short)|uniprotkb:KIAA1219(gene name synonym)|uniprotkb:p170(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001269846.1|refseq:NP_001269847.1|refseq:NP_065069.1|ensembl:ENSG00000170471(gene)|ensembl:ENST00000262879(transcript)|ensembl:ENST00000397040(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR035974|interpro:IPR039930|mint:Q86X10|reactome:R-HSA-1445148 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:xQ21jgYZlH6glqeYHnN+xDtdgRI9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q86W92 intact:EBI-25492395 intact:EBI-1045582|uniprotkb:O75336|uniprotkb:Q86X70|uniprotkb:Q9NY03|uniprotkb:Q9ULJ0|ensembl:ENSP00000314724 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lipb1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1(gene name synonym)|uniprotkb:PPFIBP1(gene name)|psi-mi:PPFIBP1(display_short)|uniprotkb:KIAA1230(gene name synonym)|uniprotkb:hSGT2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000110841(gene)|ensembl:ENST00000318304(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030437|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q86W92|reactome:R-HSA-388844|refseq:NP_001185844.1|refseq:NP_001185845.1|refseq:NP_003613.3|refseq:NP_803193.2|dip:DIP-42195N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:PIoFJHaX4lvBJ0EYcascPgJP8bI9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q86SQ0 intact:EBI-25492395 intact:EBI-2798483|uniprotkb:Q68CY3|uniprotkb:Q8NCU5|uniprotkb:Q6NT98|uniprotkb:Q59EA8|uniprotkb:A5PKZ3|uniprotkb:Q8N8U8|uniprotkb:Q8NAB1|ensembl:ENSP00000377502|ensembl:ENSP00000405405 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:phlb2_human(display_long)|uniprotkb:LL5B(gene name synonym)|uniprotkb:Protein LL5-beta(gene name synonym)|uniprotkb:PHLDB2(gene name)|psi-mi:PHLDB2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001127909.1|refseq:NP_001127910.1|refseq:NP_001127911.1|refseq:NP_665696.1|ensembl:ENSG00000144824(gene)|ensembl:ENST00000393925(transcript)|ensembl:ENST00000431670(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0031252"(cell leading edge)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045180"(basal cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|dip:DIP-42196N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:T5YIJ7WjxQlZKWAd/28wh3Znui89606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q7Z4G1 intact:EBI-25492395 intact:EBI-1550081|uniprotkb:A6NF28|uniprotkb:Q5TBK4|uniprotkb:B7ZLN0|ensembl:ENSP00000366841|ensembl:ENSP00000506987 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:comd6_human(display_long)|uniprotkb:COMMD6(gene name)|psi-mi:COMMD6(display_short)|uniprotkb:MSTP076(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_987091.1|refseq:NP_987093.1|ensembl:ENSG00000188243(gene)|ensembl:ENST00000377615(transcript)|ensembl:ENST00000682242(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR017920|reactome:R-HSA-8951664 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:73rTIbUABTRqe9OabTgdQ1QvZ7A9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q7Z3J2 intact:EBI-25492395 intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q70EL1 intact:EBI-25492395 intact:EBI-946185|intact:EBI-2798236|uniprotkb:B9ZVM1|uniprotkb:A1L4Q4|uniprotkb:A3KFK3|uniprotkb:A3KFK5|uniprotkb:A3KFK6|uniprotkb:A3KFK7|uniprotkb:A6PVS4|uniprotkb:A6PVS5|uniprotkb:A6PVS6|uniprotkb:A6PVS7|uniprotkb:B3KVY1|uniprotkb:Q5F2F4|uniprotkb:Q6ZSP1|uniprotkb:Q6ZSR1|uniprotkb:Q6ZTM0|uniprotkb:Q8N1X2|uniprotkb:Q6P1N6|ensembl:ENSP00000345216 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubp54_human(display_long)|uniprotkb:C10orf29(gene name synonym)|uniprotkb:Inactive ubiquitin-specific peptidase 54(gene name synonym)|uniprotkb:USP54(gene name)|psi-mi:USP54(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_689799.3|refseq:NP_001307366.1|refseq:XP_016871263.1|refseq:XP_016871264.1|refseq:XP_016871265.1|refseq:XP_016871266.1|ensembl:ENSG00000166348(gene)|ensembl:ENST00000339859(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|interpro:IPR038765|interpro:IPR040142|mint:Q70EL1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:TwMLO8uUiZ6onr+jyUz5D6qwZ1g9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q6ZWJ1 intact:EBI-25492395 intact:EBI-947833|uniprotkb:Q8IVZ5|ensembl:ENSP00000365530 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:stxb4_human(display_long)|uniprotkb:Syntaxin 4-interacting protein(gene name synonym)|uniprotkb:STXBP4(gene name)|psi-mi:STXBP4(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_848604.3|ensembl:ENSG00000166263(gene)|ensembl:ENST00000376352(transcript)|go:"GO:0006605"(protein targeting)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0019905"(syntaxin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0050821"(protein stabilization)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036020|interpro:IPR036034|rcsb pdb:2YSG - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:CGnaU94j8r3tB9BbrIPPYFYK5h49606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q6ZU80 intact:EBI-25492395 intact:EBI-2873150|ensembl:ENSP00000281129|ensembl:ENSP00000451162|uniprotkb:Q96ML4|uniprotkb:Q86X97|uniprotkb:B9EK52 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ce128_human(display_long)|uniprotkb:C14orf145(gene name synonym)|uniprotkb:CEP128(gene name)|psi-mi:CEP128(display_short)|uniprotkb:C14orf61(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000100629(gene)|ensembl:ENST00000281129(transcript)|ensembl:ENST00000555265(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005814"(centriole)|go:"GO:0008104"(protein localization)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR026652|go:"GO:0005737"(cytoplasm)|refseq:NP_689659.2|refseq:XP_006720119.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:tZ+lnA6Nvn/Fmx9FRxguGn2gH0k9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q6IEG0 intact:EBI-25492395 intact:EBI-2876632|uniprotkb:Q5THM2|uniprotkb:Q96MK1|uniprotkb:Q5THM1|uniprotkb:Q14C91|uniprotkb:Q5T339|uniprotkb:A8K8P4|ensembl:ENSP00000339834 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:snr48_human(display_long)|uniprotkb:SNRNP48(gene name)|psi-mi:SNRNP48(display_short)|uniprotkb:C6orf151(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_689764.3|ensembl:ENSG00000168566(gene)|ensembl:ENST00000342415(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR022776|interpro:IPR032845|interpro:IPR036236|rcsb pdb:2VY4|rcsb pdb:2VY5|reactome:R-HSA-72165 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:xKzG44rRn2jI0igYZDuk2eP7+Eg9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q6GYQ0 intact:EBI-25492395 intact:EBI-3957100|uniprotkb:A6NMA4|uniprotkb:C5NU19|uniprotkb:O94960|uniprotkb:Q6GYP9|uniprotkb:Q6ZT23|uniprotkb:Q86YF3|uniprotkb:Q86YF5|uniprotkb:Q8ND69|uniprotkb:B9EK38|ensembl:ENSP00000374348 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rgpa1_human(display_long)|uniprotkb:RALGAPA1(gene name)|psi-mi:RALGAPA1(display_short)|uniprotkb:GARNL1(gene name synonym)|uniprotkb:KIAA0884(gene name synonym)|uniprotkb:TULIP1(gene name synonym)|uniprotkb:GAP-related-interacting partner to E12(gene name synonym)|uniprotkb:GTPase-activating Rap/Ran-GAP domain-like 1(gene name synonym)|uniprotkb:Tuberin-like protein 1(gene name synonym)|uniprotkb:p240(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001269972.1|refseq:NP_001269973.1|refseq:NP_055805.1|refseq:NP_919277.2|refseq:NP_001333172.1|refseq:NP_001333174.1|refseq:NP_001333175.1|refseq:NP_001333176.1|refseq:NP_001333177.1|refseq:NP_001333178.1|refseq:NP_001317004.1|ensembl:ENSG00000174373(gene)|ensembl:ENST00000389698(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027107|interpro:IPR035974|mint:Q6GYQ0|reactome:R-HSA-9013407 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:355FJfQ+hIi8gkQQ+IAsF6xHuKU9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q63ZY3 intact:EBI-25492395 intact:EBI-2556193|uniprotkb:Q9H8S4|uniprotkb:Q6GUF5|uniprotkb:Q9NUP0|uniprotkb:Q3KQZ3|uniprotkb:B0I1P4|uniprotkb:Q9P210|ensembl:ENSP00000465650 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:kank2_human(display_long)|uniprotkb:ANKRD25(gene name synonym)|uniprotkb:KIAA1518(gene name synonym)|uniprotkb:MXRA3(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 25(gene name synonym)|uniprotkb:SRC-1-interacting protein(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 3(gene name synonym)|uniprotkb:KANK2(gene name)|psi-mi:KANK2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001129663.1|refseq:NP_056308.3|rcsb pdb:6TMD|ensembl:ENSG00000197256(gene)|ensembl:ENST00000586659(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0070563"(negative regulation of vitamin D receptor signaling pathway)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|mint:Q63ZY3|rcsb pdb:4HBD|rcsb pdb:5YBV|refseq:NP_001316380.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:5lZ6UWmx5+N6B1B/xTmVfvxA7Ag9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q5VUJ6 intact:EBI-25492395 intact:EBI-2659666|uniprotkb:Q9P233|uniprotkb:Q9HA88|uniprotkb:F5H2T1|uniprotkb:Q08AD5|ensembl:ENSP00000325091 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lrch2_human(display_long)|uniprotkb:KIAA1495(gene name synonym)|uniprotkb:LRCH2(gene name)|psi-mi:LRCH2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_065922.3|refseq:NP_001230892.1|ensembl:ENSG00000130224(gene)|ensembl:ENST00000317135(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:hjJwBxAeVmoDWTtcKK5NzCIDnBo9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q5SZL2 intact:EBI-25492395 intact:EBI-2514702|ensembl:ENSP00000357477|uniprotkb:Q2TAM2|uniprotkb:Q9H289|uniprotkb:A1A4E1|uniprotkb:A2IDE5|uniprotkb:Q5T323|uniprotkb:Q7Z5K7|uniprotkb:A2A3P2|uniprotkb:F8W6J2|uniprotkb:G3V0H3 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ce85l_human(display_long)|uniprotkb:CEP85L(gene name)|psi-mi:CEP85L(display_short)|uniprotkb:C6orf204(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-15(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000111860(gene)|ensembl:ENST00000368491(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|interpro:IPR029778|interpro:IPR040210|refseq:XP_011534111.1|refseq:NP_001035940.1|refseq:NP_001171506.1|refseq:NP_996804.2|refseq:XP_016866335.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:N15ebFbq7U88FFmEjre+dOJsgeA9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q5SVZ6 intact:EBI-25492395 intact:EBI-2555834|uniprotkb:Q7Z3Q4|ensembl:ENSP00000352920|ensembl:ENSP00000362427|ensembl:ENSP00000482579|ensembl:ENSP00000496876|uniprotkb:D3DPR7 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zmym1_human(display_long)|uniprotkb:ZMYM1(gene name)|psi-mi:ZMYM1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_079048.3|ensembl:ENSG00000197056(gene)|ensembl:ENST00000359858(transcript)|ensembl:ENST00000373330(transcript)|ensembl:ENST00000611874(transcript)|ensembl:ENST00000650449(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008906(HAT dimerisation)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025398|mint:Q5SVZ6|refseq:NP_001306884.1|ensembl:ENSP00000352920|ensembl:ENSP00000362427|ensembl:ENSP00000482579|ensembl:ENSP00000496876|refseq:NP_001276017.1|refseq:NP_001276018.1|refseq:NP_001276019.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:Mi/JhPhavQr3W2r/4xHAGfYjMWE9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q567U6 intact:EBI-25492395 intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q53EZ4 intact:EBI-25492395 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q15345 intact:EBI-25492395 intact:EBI-721408|uniprotkb:A8K5G8|uniprotkb:Q3MJ96|uniprotkb:Q5TDF5|uniprotkb:Q71RA8|uniprotkb:Q9BSM0|ensembl:ENSP00000343298|ensembl:ENSP00000477792 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lrc41_human(display_long)|uniprotkb:Protein Muf1(gene name synonym)|uniprotkb:LRRC41(gene name)|psi-mi:LRRC41(display_short)|uniprotkb:PP7759(orf name)|uniprotkb:MUF1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_006360.3|ensembl:ENSG00000132128(gene)|ensembl:ENST00000343304(transcript)|ensembl:ENST00000617190(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|interpro:IPR026137|interpro:IPR032675|reactome:R-HSA-8951664|reactome:R-HSA-9706019|reactome:R-HSA-983168 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:56q0Bi44fuNOnpKChVlLLpY4/I09606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q13188 intact:EBI-25492395 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q13049 intact:EBI-25492395 intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q13043 intact:EBI-25492395 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q12923 intact:EBI-25492395 intact:EBI-355227|uniprotkb:Q9UDA8|uniprotkb:Q15159|uniprotkb:Q15263|uniprotkb:Q15264|uniprotkb:Q15265|uniprotkb:Q15674|uniprotkb:Q16826|uniprotkb:Q8IWH7|uniprotkb:Q9NYN9|uniprotkb:B2RTR0|ensembl:ENSP00000407249 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ptn13_human(display_long)|uniprotkb:PTPN13(gene name)|psi-mi:PTPN13(display_short)|uniprotkb:PNP1(gene name synonym)|uniprotkb:PTP1E(gene name synonym)|uniprotkb:PTPL1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1E(gene name synonym)|uniprotkb:PTP-BAS(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PTPL1(gene name synonym)|uniprotkb:Fas-associated protein-tyrosine phosphatase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_006255.1|refseq:NP_542414.1|refseq:NP_542415.1|refseq:NP_542416.1|ensembl:ENST00000316707|ensembl:ENSP00000322675|ensembl:ENSP00000407249|ensembl:ENST00000427191|ensembl:ENSP00000408368|ensembl:ENST00000436978|ensembl:ENSP00000394794|ensembl:ENST00000511467|ensembl:ENSP00000426626|dip:DIP-40449N|ensembl:ENSG00000163629(gene)|ensembl:ENST00000411767(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030027"(lamellipodium)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR011019(KIND)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012153(Protein-tyrosine phosphatase, non-receptor type-13)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029021|interpro:IPR029071|interpro:IPR035963|interpro:IPR036034|mint:Q12923|rcsb pdb:1D5G|rcsb pdb:1Q7X|go:"GO:0001933"(negative regulation of protein phosphorylation)|rcsb pdb:1WCH|rcsb pdb:2M0Z|rcsb pdb:2M10|rcsb pdb:3LNX|rcsb pdb:3LNY|rcsb pdb:3PDZ|rcsb pdb:5GLJ|reactome:R-HSA-1660499|reactome:R-HSA-9008059|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:PU9d6x+mLnjomT1yfPSVBg0i2Bk9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:Q05086 intact:EBI-25492395 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:P51530 intact:EBI-25492395 intact:EBI-6677369|ensembl:ENSP00000351185|uniprotkb:Q2NKM1|uniprotkb:Q5TC49|uniprotkb:Q5TC50|uniprotkb:Q6P455|uniprotkb:Q6PI80|uniprotkb:Q7Z6H9|uniprotkb:Q8N346 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dna2_human(display_long)|uniprotkb:DNA2(gene name)|psi-mi:DNA2(display_short)|uniprotkb:DNA2L(gene name synonym)|uniprotkb:KIAA0083(gene name synonym)|uniprotkb:DNA replication ATP-dependent helicase-like homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000138346(gene)|ensembl:ENST00000358410(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0033567"(DNA replication, Okazaki fragment processing)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071932"(replication fork reversal)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0090656"(t-circle formation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR014808(DNA replication factor Dna2)|interpro:IPR026851|interpro:IPR027417|interpro:IPR041677|interpro:IPR041679|rcsb pdb:5EAY|reactome:R-HSA-174437|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69166|reactome:R-HSA-69473|refseq:NP_001073918.2 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:ftL7EgRB3WfppiSav6gChBIOMZs9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:P28838 intact:EBI-25492395 intact:EBI-2339312|uniprotkb:Q6IAM6|uniprotkb:Q6P0L6|uniprotkb:Q9UQE3|uniprotkb:B3KMQ3|ensembl:ENSP00000226299|ensembl:ENSP00000481000 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ampl_human(display_long)|uniprotkb:LAP3(gene name)|psi-mi:LAP3(display_short)|uniprotkb:LAPEP(gene name synonym)|uniprotkb:PEPS(gene name synonym)|uniprotkb:Leucyl aminopeptidase(gene name synonym)|uniprotkb:Leucine aminopeptidase 3(gene name synonym)|uniprotkb:Proline aminopeptidase(gene name synonym)|uniprotkb:Prolyl aminopeptidase(gene name synonym)|uniprotkb:Peptidase S(gene name synonym)|uniprotkb:Cysteinylglycine-S-conjugate dipeptidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_056991.2|ensembl:ENSG00000002549(gene)|ensembl:ENST00000226299(transcript)|ensembl:ENST00000618908(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030496"(midbody)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000819(Peptidase M17, leucyl aminopeptidase, C-terminal)|interpro:IPR008283(Peptidase M17, leucyl aminopeptidase, N-terminal)|interpro:IPR011356(Peptidase M17, leucyl aminopeptidase)|interpro:IPR023042|interpro:IPR043472|mint:P28838 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:BGEwM09Jm/Nn1CwI+QguAqIwGzw9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:O95754 intact:EBI-25492395 intact:EBI-20855345|ensembl:ENSP00000350547|uniprotkb:Q542Y7|uniprotkb:Q9NS35 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sem4f_human(display_long)|uniprotkb:Semaphorin-M(gene name synonym)|uniprotkb:Semaphorin-W(gene name synonym)|uniprotkb:SEMA4F(gene name)|psi-mi:SEMA4F(display_short)|uniprotkb:SEMAM(gene name synonym)|uniprotkb:SEMAW(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000135622(gene)|ensembl:ENST00000357877(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0043204"(perikaryon)|go:"GO:0016020"(membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015512(Seamphorin 4F)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|reactome:R-HSA-9696264|refseq:NP_001258590.1|refseq:NP_001258591.1|refseq:NP_004254.2 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:z8am1USD1jvpKvFCjI4aLDNXIlc9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:O95714 intact:EBI-25492395 intact:EBI-1058922|uniprotkb:Q86SV7|uniprotkb:Q86SV8|uniprotkb:Q86SV9|uniprotkb:Q86YY3|uniprotkb:Q86YY4|uniprotkb:Q86YY5|uniprotkb:Q86YY6|uniprotkb:Q86YY7|uniprotkb:Q86YY8|uniprotkb:Q86YY9|uniprotkb:Q86YZ0|uniprotkb:Q86YZ1|intact:EBI-1104961|intact:EBI-28977852|ensembl:ENSP00000261609 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:herc2_human(display_long)|uniprotkb:HERC2(gene name)|psi-mi:HERC2(display_short)|uniprotkb:HECT domain and RCC1-like domain-containing protein 2(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HERC2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000261609|refseq:NP_004658.3|ensembl:ENSG00000128731(gene)|ensembl:ENST00000261609(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032183"(SUMO binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR000569(HECT)|interpro:IPR001199(Cytochrome b5)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR006624(Beta-propeller repeat TECPR)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR010606(Mib-herc2)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR021097|interpro:IPR035983|interpro:IPR036400|interpro:IPR037252|interpro:IPR037976|interpro:IPR041987|interpro:IPR043145|mint:O95714|rcsb pdb:2KEO|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:3KCI|rcsb pdb:4L1M|rcsb pdb:6WW4|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|reactome:R-HSA-983168|rcsb pdb:6WW3|dip:DIP-37632N - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:ejMTmb0F9pM7zfHbRscV1rIRgSw9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:O75665 intact:EBI-25492395 intact:EBI-716327|uniprotkb:B9ZVU5|uniprotkb:O75666|uniprotkb:Q4VAK4|ensembl:ENSP00000344314 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ofd1_human(display_long)|uniprotkb:Protein 71-7A(gene name synonym)|uniprotkb:CXorf5(gene name synonym)|uniprotkb:OFD1(gene name)|psi-mi:OFD1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_003602.1|refseq:NP_001317138.1|dip:DIP-60601N|ensembl:ENSG00000046651(gene)|ensembl:ENST00000340096(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031514"(motile cilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|interpro:IPR006594(LisH dimerisation motif)|mint:O75665|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:4d914S9tjw9uPYU9bJ0AKx7iaRE9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:O75382 intact:EBI-25492395 intact:EBI-2129889|uniprotkb:Q4V9L4|uniprotkb:Q9C038|uniprotkb:Q9C039|uniprotkb:B7Z5E6|uniprotkb:F5H2Q8|ensembl:ENSP00000340797|ensembl:ENSP00000352508|ensembl:ENSP00000433102 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:trim3_human(display_long)|uniprotkb:TRIM3(gene name)|psi-mi:TRIM3(display_short)|uniprotkb:BERP(gene name synonym)|uniprotkb:RNF22(gene name synonym)|uniprotkb:RNF97(gene name synonym)|uniprotkb:RING finger protein 22(gene name synonym)|uniprotkb:Brain-expressed RING finger protein(gene name synonym)|uniprotkb:RING finger protein 97(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011518146.1|refseq:XP_011518147.1|refseq:NP_006449.2|refseq:NP_150594.2|refseq:XP_016872587.1|refseq:XP_016872588.1|refseq:NP_001234935.1|refseq:NP_001234936.1|ensembl:ENSG00000110171(gene)|ensembl:ENST00000345851(transcript)|ensembl:ENST00000359518(transcript)|ensembl:ENST00000525074(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007399"(nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001258(NHL repeat)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR017907|interpro:IPR027370|mint:O75382|reactome:R-HSA-877300 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:Vz2XqDSJXAWxxubxtghV91m9K009606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:O60826 intact:EBI-25492395 intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1 - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449633 uniprotkb:O43933 intact:EBI-25492395 intact:EBI-988601|uniprotkb:Q96S71|uniprotkb:Q96S72|uniprotkb:Q96S73|uniprotkb:Q99994|ensembl:ENSP00000248633|uniprotkb:A8KA90|uniprotkb:A4D1G3|uniprotkb:B4DIM7|uniprotkb:E9PE75 psi-mi:p0dtd1-pro_0000449633(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pex1_human(display_long)|uniprotkb:Peroxin-1(gene name synonym)|uniprotkb:Peroxisome biogenesis disorder protein 1(gene name synonym)|uniprotkb:PEX1(gene name)|psi-mi:PEX1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375521|imex:IM-28441-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001269606.1|refseq:NP_001269607.1|refseq:NP_000457.1|ensembl:ENSG00000127980(gene)|ensembl:ENST00000248633(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0060152"(microtubule-based peroxisome localization)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015342(Peroxisome biogenesis factor 1, N-terminal)|interpro:IPR015343(Peroxisome biogenesis factor 1, alpha/beta)|interpro:IPR025653|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:O43933|reactome:R-HSA-9033241|go:"GO:0070062"(extracellular exosome) - chain-seq-start:6799|chain-seq-end:7096 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:TnbLJN5Q4tX5IUV/hhNkiSyxMsE2697049 rogid:tc6YxVhySlqqv5/zhBkZ5pvv6/M9606 rigid:NKGiOYFM/4pNVGJkbDRxdEika/s false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449620 uniprotkb:Q6Y7W6 intact:EBI-25475859 intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537 psi-mi:p0dtd1-pro_0000449620(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375644|imex:IM-28441-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent) refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606 rigid:owZV2LhjxG2bvnZdanGJVdJv6yE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449620 uniprotkb:Q5T1M5 intact:EBI-25475859 intact:EBI-5235934|uniprotkb:Q05DK8|uniprotkb:Q5T1M2|uniprotkb:Q6DD85|uniprotkb:Q9Y4D0|ensembl:ENSP00000238256|ensembl:ENSP00000416158 psi-mi:p0dtd1-pro_0000449620(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fkb15_human(display_long)|uniprotkb:FKBP15(gene name)|psi-mi:FKBP15(display_short)|uniprotkb:KIAA0674(gene name synonym)|uniprotkb:133 kDa FK506-binding protein(gene name synonym)|uniprotkb:WASP- and FKBP-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375644|imex:IM-28441-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent) refseq:NP_056073.1|refseq:XP_006717081.1|ensembl:ENSG00000119321(gene)|ensembl:ENST00000238256(transcript)|ensembl:ENST00000446284(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|mint:Q5T1M5 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:2th35ZHTzidVTyWGpc0Emz3foIY9606 rigid:owZV2LhjxG2bvnZdanGJVdJv6yE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449620 uniprotkb:Q2M389 intact:EBI-25475859 intact:EBI-2563783|uniprotkb:Q8IW61|uniprotkb:Q9NVD6|uniprotkb:Q8N5W7|uniprotkb:Q2NL83|uniprotkb:Q9UPW7|ensembl:ENSP00000328062 psi-mi:p0dtd1-pro_0000449620(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wasc4_human(display_long)|uniprotkb:WASHC4(gene name)|psi-mi:WASHC4(display_short)|uniprotkb:KIAA1033(gene name synonym)|uniprotkb:Strumpellin and WASH-interacting protein(gene name synonym)|uniprotkb:WASH complex subunit SWIP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375644|imex:IM-28441-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent) refseq:NP_056090.1|ensembl:ENSG00000136051(gene)|ensembl:ENST00000332180(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0007032"(endosome organization)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0071203"(WASH complex)|go:"GO:0140591"(nuclear envelope budding)|interpro:IPR027307|interpro:IPR028191|interpro:IPR028283|interpro:IPR028282|refseq:NP_001280569.1 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:APnP9mxAqwzKEoQFGt94Z8Y73t49606 rigid:owZV2LhjxG2bvnZdanGJVdJv6yE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449620 uniprotkb:P52306 intact:EBI-25475859 intact:EBI-746389|uniprotkb:Q9BUW9|ensembl:ENSP00000386153|intact:EBI-3184182|uniprotkb:G5E9P9|uniprotkb:Q499L7|uniprotkb:Q4KMV2|uniprotkb:Q9BUX6|uniprotkb:Q9NYM2|uniprotkb:Q9NZA8|intact:EBI-4397492|uniprotkb:E9PH06|uniprotkb:Q4QQI8|intact:EBI-11106358 psi-mi:p0dtd1-pro_0000449620(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gds1_human(display_long)|uniprotkb:RAP1GDS1(gene name)|psi-mi:RAP1GDS1(display_short)|uniprotkb:Exchange factor smgGDS(gene name synonym)|uniprotkb:SMG GDS protein(gene name synonym)|uniprotkb:SMG P21 stimulatory GDP/GTP exchange protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375644|imex:IM-28441-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent) refseq:NP_066982.3|refseq:NP_001093898.1|ensembl:ENSG00000138698(gene)|ensembl:ENST00000408927(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040144|rcsb pdb:5XGC|rcsb pdb:5ZHX|reactome:R-HSA-9013419|reactome:R-HSA-9013425|refseq:NP_001093896.1|refseq:NP_001093897.1|refseq:NP_001093899.1|refseq:NP_001093900.1|dip:DIP-61080N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:CBqwhiENmk65uN7XyiVVYZ+W6R09606 rigid:owZV2LhjxG2bvnZdanGJVdJv6yE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449620 uniprotkb:P16435 intact:EBI-25475859 intact:EBI-726554|uniprotkb:Q9UDT3|uniprotkb:Q16455|uniprotkb:Q8N181|uniprotkb:Q9H3M8|uniprotkb:Q197M5|ensembl:ENSP00000378355|ensembl:ENSP00000389409|ensembl:ENSP00000389719|ensembl:ENSP00000390540|ensembl:ENSP00000395813|ensembl:ENSP00000399327|ensembl:ENSP00000399556|ensembl:ENSP00000404731|ensembl:ENSP00000409238|ensembl:ENSP00000414263|ensembl:ENSP00000419970 psi-mi:p0dtd1-pro_0000449620(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ncpr_human(display_long)|uniprotkb:POR(gene name)|psi-mi:POR(display_short)|uniprotkb:CYPOR(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375644|imex:IM-28441-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent) refseq:NP_000932.3|ensembl:ENSG00000127948(gene)|ensembl:ENST00000394893(transcript)|ensembl:ENST00000412064(transcript)|ensembl:ENST00000412521(transcript)|ensembl:ENST00000414186(transcript)|ensembl:ENST00000418341(transcript)|ensembl:ENST00000432753(transcript)|ensembl:ENST00000439963(transcript)|ensembl:ENST00000449920(transcript)|ensembl:ENST00000453773(transcript)|ensembl:ENST00000454934(transcript)|ensembl:ENST00000461988(transcript)|go:"GO:0003420"(regulation of growth plate cartilage chondrocyte proliferation)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009725"(response to hormone)|go:"GO:0009812"(flavonoid metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0016787"(hydrolase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0022900"(electron transport chain)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032770"(positive regulation of monooxygenase activity)|go:"GO:0042493"|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043602"(nitrate catabolic process)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0047726"(iron-cytochrome-c reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0070988"(demethylation)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090031"(positive regulation of steroid hormone biosynthetic process)|go:"GO:0090346"(cellular organofluorine metabolic process)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR029039|interpro:IPR039261|rcsb pdb:1B1C|rcsb pdb:3FJO|rcsb pdb:3QE2|rcsb pdb:3QFC|rcsb pdb:3QFR|rcsb pdb:3QFS|rcsb pdb:3QFT|rcsb pdb:5EMN|rcsb pdb:5FA6|reactome:R-HSA-211897|dip:DIP-29682N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:Tgl0hfwgwo16Yw+kH4JIdIaRPpM9606 rigid:owZV2LhjxG2bvnZdanGJVdJv6yE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449620 uniprotkb:O60573 intact:EBI-25475859 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:p0dtd1-pro_0000449620(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375644|imex:IM-28441-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent) refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 rigid:owZV2LhjxG2bvnZdanGJVdJv6yE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449620 uniprotkb:O14975 intact:EBI-25475859 intact:EBI-2801436|uniprotkb:Q53FY6|uniprotkb:A8K2J7|uniprotkb:Q6PF09|ensembl:ENSP00000267842 psi-mi:p0dtd1-pro_0000449620(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:s27a2_human(display_long)|uniprotkb:ACSVL1(gene name synonym)|uniprotkb:FACVL1(gene name synonym)|uniprotkb:FATP2(gene name synonym)|uniprotkb:VLACS(gene name synonym)|uniprotkb:Fatty acid transport protein 2(gene name synonym)|uniprotkb:Fatty-acid-coenzyme A ligase, very long-chain 1(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Solute carrier family 27 member 2(gene name synonym)|uniprotkb:THCA-CoA ligase(gene name synonym)|uniprotkb:Very long-chain-fatty-acid-CoA ligase(gene name synonym)|uniprotkb:SLC27A2(gene name)|psi-mi:SLC27A2(display_short)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375644|imex:IM-28441-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent) refseq:NP_001153101.1|refseq:NP_003636.2|ensembl:ENSG00000140284(gene)|ensembl:ENST00000267842(transcript)|go:"GO:0001561"(fatty acid alpha-oxidation)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0047747"(cholate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0097089"(methyl-branched fatty acid metabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR030305|interpro:IPR042099|mint:O14975|reactome:R-HSA-193368|reactome:R-HSA-193775|reactome:R-HSA-389599|reactome:R-HSA-6798695|reactome:R-HSA-9033241 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:lOeY1DAlhT5ZfNd5gUhEBBvszws9606 rigid:owZV2LhjxG2bvnZdanGJVdJv6yE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449622 uniprotkb:Q9Y5J7 intact:EBI-25475862 intact:EBI-1200370|uniprotkb:B2R584|ensembl:ENSP00000378588|ensembl:ENSP00000450638|ensembl:ENSP00000451006|ensembl:ENSP00000451198 psi-mi:p0dtd1-pro_0000449622(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tim9_human(display_long)|uniprotkb:TIMM9(gene name)|psi-mi:TIMM9(display_short)|uniprotkb:TIM9(gene name synonym)|uniprotkb:TIM9A(gene name synonym)|uniprotkb:TIMM9A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375667|imex:IM-28441-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001291415.1|refseq:NP_001291414.1|refseq:NP_001291416.1|refseq:NP_001291417.1|refseq:NP_001291418.1|refseq:NP_001291419.1|refseq:NP_001291420.1|refseq:NP_036592.1|ensembl:ENSG00000100575(gene)|ensembl:ENST00000395159(transcript)|ensembl:ENST00000555061(transcript)|ensembl:ENST00000555404(transcript)|ensembl:ENST00000555593(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032977"(membrane insertase activity)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0051087"(chaperone binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|rcsb pdb:2BSK|rcsb pdb:7CGP|reactome:R-HSA-1268020|go:"GO:0008270"(zinc ion binding) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:a/L4LPXEAEVYZ54duHzDlaBt9W49606 rigid:oIgysJF0CpMpX6tLX1DrVNkoSBY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449622 uniprotkb:Q9Y5J6 intact:EBI-25475862 intact:EBI-1200382|uniprotkb:Q96FF3|ensembl:ENSP00000254616|ensembl:ENSP00000436948 psi-mi:p0dtd1-pro_0000449622(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:t10b_human(display_long)|uniprotkb:TIMM10B(gene name)|psi-mi:TIMM10B(display_short)|uniprotkb:FXC1(gene name synonym)|uniprotkb:Fracture callus protein 1(gene name synonym)|uniprotkb:FxC1(gene name synonym)|uniprotkb:Mitochondrial import inner membrane translocase subunit Tim9 B(gene name synonym)|uniprotkb:TIM9B(gene name synonym)|uniprotkb:TIMM10B(gene name synonym)|uniprotkb:TIMM9B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375667|imex:IM-28441-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_036324.1|ensembl:ENSG00000132286(gene)|ensembl:ENST00000254616(transcript)|ensembl:ENST00000533379(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0042721"(TIM22 mitochondrial import inner membrane insertion complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|rcsb pdb:7CGP|reactome:R-HSA-1268020 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:mD/o3O0uLaBqAgNraHE4on26AHs9606 rigid:oIgysJF0CpMpX6tLX1DrVNkoSBY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449622 uniprotkb:Q9NVH1 intact:EBI-25475862 intact:EBI-1055336|uniprotkb:Q4VWF5|uniprotkb:Q5VZN0|uniprotkb:Q6PK20|uniprotkb:Q6PK70|uniprotkb:Q8NDM2|uniprotkb:Q96CL7|ensembl:ENSP00000366800 psi-mi:p0dtd1-pro_0000449622(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:djc11_human(display_long)|uniprotkb:DNAJC11(gene name)|psi-mi:DNAJC11(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375667|imex:IM-28441-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_060668.2|ensembl:ENSG00000007923(gene)|ensembl:ENST00000377577(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0042407"(cristae formation)|go:"GO:0140275"(MIB complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR024586|interpro:IPR036869|mint:Q9NVH1|reactome:R-HSA-8949613 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:+I9CW/QUSn5NIkn2CRTFzq50c/I9606 rigid:oIgysJF0CpMpX6tLX1DrVNkoSBY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449622 uniprotkb:Q9BSF4 intact:EBI-25475862 intact:EBI-10974729|ensembl:ENSP00000270502|uniprotkb:Q96EY6|uniprotkb:Q96IT8 psi-mi:p0dtd1-pro_0000449622(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tim29_human(display_long)|uniprotkb:TIMM29(gene name)|psi-mi:TIMM29(display_short)|uniprotkb:c19orf52(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375667|imex:IM-28441-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_612367.1|ensembl:ENSG00000142444(gene)|ensembl:ENST00000270502(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042721"(TIM22 mitochondrial import inner membrane insertion complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR019322|rcsb pdb:7CGP - chain-seq-start:2764|chain-seq-end:3263 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:9RRT6AC0o31q81ETOTJgq3Gk+2E9606 rigid:oIgysJF0CpMpX6tLX1DrVNkoSBY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449622 uniprotkb:Q8TEM1 intact:EBI-25475862 intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508 psi-mi:p0dtd1-pro_0000449622(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375667|imex:IM-28441-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606 rigid:oIgysJF0CpMpX6tLX1DrVNkoSBY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449622 uniprotkb:Q2TAA5 intact:EBI-25475862 intact:EBI-1048799|uniprotkb:A5PLP3|uniprotkb:Q5TAN9|uniprotkb:Q6DKI6|uniprotkb:Q96FI7|uniprotkb:B4DKW9|ensembl:ENSP00000430236 psi-mi:p0dtd1-pro_0000449622(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:alg11_human(display_long)|uniprotkb:ALG11(gene name)|psi-mi:ALG11(display_short)|uniprotkb:GT8(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 11 homolog(gene name synonym)|uniprotkb:Glycolipid 2-alpha-mannosyltransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375667|imex:IM-28441-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001004127.2|ensembl:ENSG00000253710(gene)|ensembl:ENST00000521508(transcript)|go:"GO:0000026"(alpha-1,2-mannosyltransferase activity)|go:"GO:0004377"("GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006490"(oligosaccharide-lipid intermediate biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR031814|interpro:IPR038013|reactome:R-HSA-446193|reactome:R-HSA-4551295 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:OjwuNTUYh/E2R1APeB1qD9lqsOs9606 rigid:oIgysJF0CpMpX6tLX1DrVNkoSBY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449622 uniprotkb:P62072 intact:EBI-25475862 intact:EBI-1200391|uniprotkb:Q9WV99|uniprotkb:Q9WVA0|uniprotkb:Q9Y5J8|uniprotkb:A8K136|ensembl:ENSP00000257245|ensembl:ENSP00000433627|ensembl:ENSP00000435678 psi-mi:p0dtd1-pro_0000449622(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tim10_human(display_long)|uniprotkb:TIMM10(gene name)|psi-mi:TIMM10(display_short)|uniprotkb:TIM10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375667|imex:IM-28441-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_036588.1|ensembl:ENSG00000134809(gene)|ensembl:ENST00000257245(transcript)|ensembl:ENST00000525158(transcript)|ensembl:ENST00000525587(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032977"(membrane insertase activity)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0051087"(chaperone binding)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR027100|interpro:IPR035427|rcsb pdb:2BSK|rcsb pdb:7CGP|reactome:R-HSA-1268020|go:"GO:0007605"(sensory perception of sound) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:8Ygf3Hjx342xU28Mggg7oTD6hAQ9606 rigid:oIgysJF0CpMpX6tLX1DrVNkoSBY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449622 uniprotkb:P14735 intact:EBI-25475862 intact:EBI-2556886|uniprotkb:Q5T5N2|uniprotkb:D3DR35|ensembl:ENSP00000265986|uniprotkb:B2R721|uniprotkb:B7ZAU2 psi-mi:p0dtd1-pro_0000449622(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ide_human(display_long)|uniprotkb:IDE(gene name)|psi-mi:IDE(display_short)|uniprotkb:Insulin protease(gene name synonym)|uniprotkb:Insulysin(gene name synonym)|uniprotkb:Abeta-degrading protease(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375667|imex:IM-28441-87 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_004960.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010815"(bradykinin catabolic process)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031626"(beta-endorphin binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000119912(gene)|ensembl:ENST00000265986(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0043559"(insulin binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1901143"(insulin catabolic process)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|mint:P14735|rcsb pdb:2G47|rcsb pdb:2G48|rcsb pdb:2G49|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2JBU|rcsb pdb:2JG4|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WK3|rcsb pdb:2YPU|rcsb pdb:3CWW|rcsb pdb:3E4A|rcsb pdb:3E4Z|rcsb pdb:3E50|rcsb pdb:3H44|rcsb pdb:3N56|rcsb pdb:3N57|rcsb pdb:3OFI|rcsb pdb:3QZ2|rcsb pdb:4DTT|rcsb pdb:4DWK|rcsb pdb:4GS8|rcsb pdb:4GSC|rcsb pdb:4GSF|rcsb pdb:4IFH|rcsb pdb:4IOF|rcsb pdb:4LTE|rcsb pdb:4M1C|rcsb pdb:4NXO|rcsb pdb:4PES|rcsb pdb:4PF7|rcsb pdb:4PF9|rcsb pdb:4PFC|rcsb pdb:4QIA|rcsb pdb:4RAL|rcsb pdb:4RE9|rcsb pdb:5CJO|rcsb pdb:3HGZ|rcsb pdb:5UOE|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6B7Y|rcsb pdb:6BF6|rcsb pdb:6BF7|rcsb pdb:6BF8|rcsb pdb:6BF9|rcsb pdb:6BFC|rcsb pdb:6BYZ|rcsb pdb:6EDS|rcsb pdb:6MQ3|reactome:R-HSA-5689880|reactome:R-HSA-9033241|rcsb pdb:6B7Z|refseq:NP_001159418.1|dip:DIP-55771N - chain-seq-start:2764|chain-seq-end:3263 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/27 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:dwngN3kUOExC5qapSgF01YhBNAM9606 rigid:oIgysJF0CpMpX6tLX1DrVNkoSBY false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449623 uniprotkb:Q92769 intact:EBI-25475864 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:p0dtd1-pro_0000449623(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375713|imex:IM-28441-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - chain-seq-start:3264|chain-seq-end:3569 - figure legend:Table 2, no 15|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:9u1TJXDTORfCyqj2bv2TlDMZ65c2697049 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:MZh6D9xIaWOai2cbdTRYi7QdMXA false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449623 uniprotkb:P07203 intact:EBI-25475864 intact:EBI-7209024|uniprotkb:E9PAS1|ensembl:ENSP00000407375|uniprotkb:Q7Z5H1|uniprotkb:Q9BW12|intact:UNK-5370138 psi-mi:p0dtd1-pro_0000449623(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gpx1_human(display_long)|uniprotkb:GPX1(gene name)|psi-mi:GPX1(display_short)|uniprotkb:Cellular glutathione peroxidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375721|imex:IM-28441-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_000572.2|ensembl:ENSG00000233276(gene)|ensembl:ENST00000419783(transcript)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001885"(endothelial cell development)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009609"(response to symbiotic bacterium)|go:"GO:0009650"(UV protection)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042311"(vasodilation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060047"(heart contraction)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902905"(positive regulation of supramolecular fiber organization)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|mint:P07203|rcsb pdb:2F8A|reactome:R-HSA-2142688|reactome:R-HSA-2142712|reactome:R-HSA-2142770|reactome:R-HSA-3299685|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0061136"(regulation of proteasomal protein catabolic process) - chain-seq-start:3264|chain-seq-end:3569 comment:mint|comment:homomint|function:Protects the hemoglobin in erythrocytes from oxidative breakdown figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:9u1TJXDTORfCyqj2bv2TlDMZ65c2697049 rogid:1/6I8LekGumy+rLlaLFqCbl1gV09606 rigid:zxBGGLrQkqdua3mY/20FtDLo7Xg false mutation causing an interaction:145-145|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449623 uniprotkb:Q9NXH9 intact:EBI-25475864 intact:EBI-748900|uniprotkb:O76103|uniprotkb:Q548Y5|uniprotkb:Q8WVA6|ensembl:ENSP00000350352|ensembl:ENSP00000416149|ensembl:ENSP00000466967 psi-mi:p0dtd1-pro_0000449623(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:trm1_human(display_long)|uniprotkb:"tRNA(guanine-26,N(2)-N(2)) methyltransferase"(gene name synonym)|uniprotkb:tRNA 2,2-dimethylguanosine-26 methyltransferase(gene name synonym)|uniprotkb:"tRNA(m(2,2)G26)dimethyltransferase"(gene name synonym)|uniprotkb:TRMT1(gene name)|psi-mi:TRMT1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375721|imex:IM-28441-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001129507.1|refseq:NP_001136026.1|refseq:NP_060192.1|refseq:XP_016882433.1|refseq:XP_016882434.1|ensembl:ENSG00000104907(gene)|ensembl:ENST00000357720(transcript)|ensembl:ENST00000437766(transcript)|ensembl:ENST00000592062(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002940"(tRNA N2-guanine methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0004809"("tRNA (guanine-N2-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002905(N2,N2-dimethylguanosine tRNA methyltransferase)|interpro:IPR029063|interpro:IPR036855|interpro:IPR042296|mint:Q9NXH9|reactome:R-HSA-6782315 - chain-seq-start:3264|chain-seq-end:3569 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:9u1TJXDTORfCyqj2bv2TlDMZ65c2697049 rogid:ty0oTgEETLwZTnDb1RFHkrkCQsU9606 rigid:zxBGGLrQkqdua3mY/20FtDLo7Xg false mutation causing an interaction:145-145|strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449624 uniprotkb:Q9H7F0 intact:EBI-25475868 intact:EBI-11722593|uniprotkb:Q8NC11|uniprotkb:Q96KS1|ensembl:ENSP00000416508|ensembl:ENSP00000494471 psi-mi:p0dtd1-pro_0000449624(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:at133_human(display_long)|uniprotkb:ATP13A3(gene name)|psi-mi:ATP13A3(display_short)|uniprotkb:AFURS1(gene name synonym)|uniprotkb:ATPase family homolog up-regulated in senescence cells 1(gene name synonym)|uniprotkb:Putrescine transporting ATPase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375731|imex:IM-28441-131 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_078800.3|refseq:XP_011511425.1|ensembl:ENSG00000133657(gene)|ensembl:ENST00000439040(transcript)|ensembl:ENST00000645538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015594"(ABC-type putrescine transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492 - chain-seq-start:3570|chain-seq-end:3859 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:gIIzGe1dPVJTqtPiF3tPJJ+4/102697049 rogid:rfv5ILI3FtufMHip3E0FrxmCTvI9606 rigid:ddVTqpYHScAByIBZd5Ev7SfzC78 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449624 uniprotkb:O75964 intact:EBI-25475868 intact:EBI-1044001|uniprotkb:Q96BV6|uniprotkb:Q9UBZ7|ensembl:ENSP00000300688|uniprotkb:A8K0K3 psi-mi:p0dtd1-pro_0000449624(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:atp5l_human(display_long)|uniprotkb:ATP5MG(gene name)|psi-mi:ATP5MG(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:ATP5L(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375731|imex:IM-28441-131 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_006467.4|ensembl:ENSG00000167283(gene)|ensembl:ENST00000300688(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:O75964|reactome:R-HSA-163210|reactome:R-HSA-8949613 - chain-seq-start:3570|chain-seq-end:3859 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:gIIzGe1dPVJTqtPiF3tPJJ+4/102697049 rogid:mn5/fFqk4xCCHb/MEuLAi5/lqmI9606 rigid:ddVTqpYHScAByIBZd5Ev7SfzC78 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449624 uniprotkb:Q99720 intact:EBI-25475868 intact:EBI-3248663|ensembl:ENSP00000277010|uniprotkb:O00673|uniprotkb:Q2TSD1|uniprotkb:Q7Z653|uniprotkb:Q153Z1|uniprotkb:Q53GN2|uniprotkb:Q9NYX0|uniprotkb:O00725|uniprotkb:Q8N7H3|uniprotkb:Q0Z9W6|uniprotkb:D3DRM7 psi-mi:p0dtd1-pro_0000449624(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sgmr1_human(display_long)|uniprotkb:SIGMAR1(gene name)|psi-mi:SIGMAR1(display_short)|uniprotkb:OPRS1(gene name synonym)|uniprotkb:SRBP(gene name synonym)|uniprotkb:Aging-associated gene 8 protein(gene name synonym)|uniprotkb:SR31747-binding protein(gene name synonym)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:AAG8(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375731|imex:IM-28441-131 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000147955(gene)|ensembl:ENST00000277010(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)|mint:Q99720|rcsb pdb:5HK1|rcsb pdb:5HK2|rcsb pdb:6DJZ|rcsb pdb:6DK0|rcsb pdb:6DK1|reactome:R-HSA-9679191|refseq:NP_005857.1|refseq:NP_671513.1|refseq:NP_001269134.1|refseq:NP_001269135.1|refseq:NP_001269136.1|refseq:NP_001269137.1|refseq:NP_001269138.1|dip:DIP-61974N - chain-seq-start:3570|chain-seq-end:3859 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:gIIzGe1dPVJTqtPiF3tPJJ+4/102697049 rogid:iEc1O6PXikkaE/0zk0A5Z7fMIZ49606 rigid:ddVTqpYHScAByIBZd5Ev7SfzC78 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449624 uniprotkb:Q15904 intact:EBI-25475868 intact:EBI-714667|uniprotkb:Q8NBT4|uniprotkb:Q9H0C7|uniprotkb:A6ZKI4|ensembl:ENSP00000358777 psi-mi:p0dtd1-pro_0000449624(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:vas1_human(display_long)|uniprotkb:V-ATPase S1 accessory protein(gene name synonym)|uniprotkb:V-ATPase Ac45 subunit(gene name synonym)|uniprotkb:Protein XAP-3(gene name synonym)|uniprotkb:ATP6AP1(gene name)|psi-mi:ATP6AP1(display_short)|uniprotkb:ATP6IP1(gene name synonym)|uniprotkb:ATP6S1(gene name synonym)|uniprotkb:VATPS1(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:Vacuolar proton pump subunit S1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375731|imex:IM-28441-131 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001174.2|ensembl:ENSG00000071553(gene)|ensembl:ENST00000369762(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045851"(pH reduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR008388(ATPase, V1 complex, subunit S1)|mint:Q15904|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-77387|reactome:R-HSA-8980692|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:XP_011529481.1 - chain-seq-start:3570|chain-seq-end:3859 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:gIIzGe1dPVJTqtPiF3tPJJ+4/102697049 rogid:c5zqmRYvzBfRy1BdJteDGueEjY49606 rigid:ddVTqpYHScAByIBZd5Ev7SfzC78 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q8WVC6 intact:EBI-25475871 intact:EBI-11319548|uniprotkb:Q9H5W1|uniprotkb:D3DX62|uniprotkb:D3DX60|uniprotkb:A8K3Z0|uniprotkb:Q9BR71|ensembl:ENSP00000308515|ensembl:ENSP00000341504|ensembl:ENSP00000413483|ensembl:ENSP00000467913|ensembl:ENSP00000478909|ensembl:ENSP00000498268 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dcakd_human(display_long)|uniprotkb:DCAKD(gene name)|psi-mi:DCAKD(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_016880591.1|refseq:XP_016880592.1|refseq:XP_016880593.1|refseq:NP_001122103.1|refseq:NP_001275583.1|refseq:NP_001275584.1|refseq:NP_079095.3|refseq:XP_005257745.1|refseq:XP_011523564.1|refseq:NP_001308255.1|ensembl:ENST00000651974(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016020"(membrane)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR027417|mint:Q8WVC6|ensembl:ENSG00000172992(gene)|ensembl:ENST00000310604(transcript)|ensembl:ENST00000342350(transcript)|ensembl:ENST00000452796(transcript)|ensembl:ENST00000588499(transcript)|ensembl:ENST00000614054(transcript) - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:b6jKOSLEjdHLqm69BmVHjW8R5G49606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q9NP72 intact:EBI-25475871 intact:EBI-722247|uniprotkb:Q53FX8|uniprotkb:Q6FIH1|uniprotkb:B3KMC7|uniprotkb:D3DRW1|intact:EBI-2859793|uniprotkb:Q56UN9|uniprotkb:B7Z333|ensembl:ENSP00000349415|ensembl:ENSP00000507542 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab18_human(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_067075.1|refseq:NP_001243339.1|refseq:NP_001243340.1|refseq:NP_001243341.1|refseq:NP_001243344.1|dip:DIP-60514N|ensembl:ENSG00000099246(gene)|ensembl:ENST00000356940(transcript)|ensembl:ENST00000682082(transcript)|go:"GO:0001654"(eye development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR025662|interpro:IPR027417|mint:Q9NP72|rcsb pdb:1X3S|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q9H7Z7 intact:EBI-25475871 intact:EBI-681645|uniprotkb:Q53EW9|uniprotkb:Q5SYV6|uniprotkb:Q96GI0|uniprotkb:Q96GL2|ensembl:ENSP00000345341 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pges2_human(display_long)|uniprotkb:Microsomal prostaglandin E synthase 2(gene name synonym)|uniprotkb:PTGES2(gene name)|psi-mi:PTGES2(display_short)|uniprotkb:PGES2(gene name synonym)|uniprotkb:C9orf15(gene name synonym)|uniprotkb:Membrane-associated prostaglandin E synthase-2(gene name synonym)|uniprotkb:"Prostaglandin-H(2) E-isomerase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001243264.1|refseq:NP_079348.1|refseq:NP_945176.1|ensembl:ENSG00000148334(gene)|ensembl:ENST00000338961(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016829"(lyase activity)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0020037"(heme binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036134"(12-hydroxyheptadecatrienoic acid synthase activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050220"(prostaglandin-E synthase activity)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034334|interpro:IPR034335|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:Q9H7Z7|reactome:R-HSA-2162123|reactome:R-HSA-6798695 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:DFALgQTHlFSBHZUZBKTJNxxSqjk9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q9BQE4 intact:EBI-25475871 intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process) - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q96DA6 intact:EBI-25475871 intact:EBI-9679081|uniprotkb:B2R4B1|uniprotkb:C9JBV1|ensembl:ENSP00000372005 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tim14_human(display_long)|uniprotkb:DNAJC19(gene name)|psi-mi:DNAJC19(display_short)|uniprotkb:TIM14(gene name synonym)|uniprotkb:TIMM14(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 19(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001177162.1|refseq:NP_660304.1|dip:DIP-62091N|ensembl:ENSG00000205981(gene)|ensembl:ENST00000382564(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048806"(genitalia development)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869|reactome:R-HSA-1268020 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:D4F4Zp25GxZQckdl1pJaBwciYik9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q96A26 intact:EBI-25475871 intact:EBI-6123466|uniprotkb:Q9NRN6|uniprotkb:Q9UJX8|ensembl:ENSP00000419088 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:f162a_human(display_long)|uniprotkb:FAM162A(gene name)|psi-mi:FAM162A(display_short)|uniprotkb:C3orf28(gene name synonym)|uniprotkb:E2IG5(gene name synonym)|uniprotkb:E2-induced gene 5 protein(gene name synonym)|uniprotkb:Growth and transformation-dependent protein(gene name synonym)|uniprotkb:DC16(orf name)|uniprotkb:FWP001(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_055182.3|ensembl:ENSG00000114023(gene)|ensembl:ENST00000477892(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR009432(Protein of unknown function DUF1075)|mint:Q96A26 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:CjOkqa9wFwEOorjQt5oI7/EJ6709606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q8WUY8 intact:EBI-25475871 intact:EBI-3919010|ensembl:ENSP00000205194|uniprotkb:Q8TDY7|uniprotkb:Q9NS72 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nat14_human(display_long)|uniprotkb:NAT14(gene name)|psi-mi:NAT14(display_short)|uniprotkb:KLP1(gene name synonym)|uniprotkb:K562 cell-derived leucine-zipper-like protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000090971(gene)|ensembl:ENST00000205194(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:Q8WUY8|refseq:NP_065111.1 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:zAcaUhoopgHpFaxfNM6H4jd4d089606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q8WTV0 intact:EBI-25475871 intact:EBI-78657|uniprotkb:Q52LZ5|uniprotkb:Q14016|uniprotkb:Q6KFX4|ensembl:ENSP00000414979|uniprotkb:F8W8N0 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:scrb1_human(display_long)|uniprotkb:SCARB1(gene name)|psi-mi:SCARB1(display_short)|uniprotkb:CD36L1(gene name synonym)|uniprotkb:CLA1(gene name synonym)|uniprotkb:SR-BI(gene name synonym)|uniprotkb:CD36 antigen-like 1(gene name synonym)|uniprotkb:CD36 and LIMPII analogous 1(gene name synonym)|uniprotkb:Collagen type I receptor, thrombospondin receptor-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005496.4|ensembl:ENSG00000073060(gene)|ensembl:ENST00000415380(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005215"(transporter activity)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010899"(regulation of phosphatidylcholine catabolic process)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015920"(lipopolysaccharide transport)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0035461"(vitamin transmembrane transport)|go:"GO:0042060"(wound healing)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070506"(high-density lipoprotein particle receptor activity)|go:"GO:0070508"(cholesterol import)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|reactome:R-HSA-3000471|reactome:R-HSA-8964011|refseq:NP_001076428.1 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:En6dno+bRV4EB8FC539pcRRMIvs9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q8NBX0 intact:EBI-25475871 intact:EBI-4289902|uniprotkb:Q9Y363|uniprotkb:Q8TAR0|ensembl:ENSP00000355467 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:scpdl_human(display_long)|uniprotkb:SCCPDH(gene name)|psi-mi:SCCPDH(display_short)|uniprotkb:CGI-49(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000143653(gene)|ensembl:ENST00000366510(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030496"(midbody)|go:"GO:0031093"(platelet alpha granule lumen)|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR032095|interpro:IPR036291|reactome:R-HSA-114608|refseq:NP_057086.2 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:3dd8OvU7odCDI/f4Ouk7CJYoxnI9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q8N183 intact:EBI-25475871 intact:EBI-2682365|uniprotkb:A8K5I1|ensembl:ENSP00000296597 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nduf2_human(display_long)|uniprotkb:NDUFA12L(gene name synonym)|uniprotkb:B17.2-like(gene name synonym)|uniprotkb:Myc-induced mitochondrial protein(gene name synonym)|uniprotkb:NDUFA12-like protein(gene name synonym)|uniprotkb:NDUFAF2(gene name)|psi-mi:NDUFAF2(display_short)|uniprotkb:Mimitin(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_777549.1|ensembl:ENSG00000164182(gene)|ensembl:ENST00000296597(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|reactome:R-HSA-6799198 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:sNje5xhXA48xAg0tSkOYiqBxZvk9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q7LGA3 intact:EBI-25475871 intact:EBI-5461291|ensembl:ENSP00000359581|uniprotkb:D3DT22|uniprotkb:O75036|uniprotkb:Q32NB5|uniprotkb:Q8TAC5|uniprotkb:Q9H441|uniprotkb:Q9NUJ9 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hs2st_human(display_long)|uniprotkb:HS2ST1(gene name)|psi-mi:HS2ST1(display_short)|uniprotkb:HS2ST(gene name synonym)|uniprotkb:KIAA0448(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000153936(gene)|ensembl:ENST00000370550(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004394"(heparan sulfate 2-O-sulfotransferase activity)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0015015"(heparan sulfate proteoglycan biosynthetic process, enzymatic modification)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007734(Heparan sulphate 2-O-sulphotransferase)|interpro:IPR027417|mint:Q7LGA3|reactome:R-HSA-2022928|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|refseq:NP_001127964.1|refseq:NP_036394.1 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:96+iUitOmSLSpaEzhZu+9fZXLEQ9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q6ZRP7 intact:EBI-25475871 intact:EBI-11127401|uniprotkb:Q7Z7B6|uniprotkb:Q8N3G2|uniprotkb:A6NLB0|uniprotkb:Q86VV7|uniprotkb:Q5TB37|uniprotkb:A2CEE0|ensembl:ENSP00000351536 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:qsox2_human(display_long)|uniprotkb:QSOX2(gene name)|psi-mi:QSOX2(display_short)|uniprotkb:Neuroblastoma-derived sulfhydryl oxidase(gene name synonym)|uniprotkb:QSCN6L1(gene name synonym)|uniprotkb:Quiescin Q6-like protein 1(gene name synonym)|uniprotkb:SOXN(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_859052.3|ensembl:ENSG00000165661(gene)|ensembl:ENST00000358701(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017905|interpro:IPR036249|interpro:IPR036774|interpro:IPR039798|interpro:IPR040986|interpro:IPR041269|interpro:IPR042568 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:P58P7yZCL+dIpUXwETr5Ppt/SQw9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q5VT66 intact:EBI-25475871 intact:EBI-11903927|uniprotkb:A8K447|uniprotkb:B2D078|uniprotkb:Q5VVS9|uniprotkb:Q5VVT0|uniprotkb:Q5VVT1|uniprotkb:Q8N9P5|uniprotkb:Q96FN8|uniprotkb:Q9H6C7|ensembl:ENSP00000355877 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:marc1_human(display_long)|uniprotkb:MTARC1(gene name)|psi-mi:MTARC1(display_short)|uniprotkb:MARC1(gene name synonym)|uniprotkb:MOSC1(gene name synonym)|uniprotkb:Molybdenum cofactor sulfurase C-terminal domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_073583.3|refseq:XP_011508202.1|refseq:XP_011508206.1|ensembl:ENSG00000186205(gene)|ensembl:ENST00000366910(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016661"(oxidoreductase activity, acting on other nitrogenous compounds as donors)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0051410"(detoxification of nitrogen compound)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|go:"GO:0098809"(nitrite reductase activity)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|rcsb pdb:6FW2|reactome:R-HSA-211945 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:MVnfGK30icFS28a9p6qf739MKYs9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q5JTV8 intact:EBI-25475871 intact:EBI-2559665|uniprotkb:Q9H8Y6|uniprotkb:Q8IZ65|uniprotkb:Q5JTV6|uniprotkb:B0QZ57|uniprotkb:Q9Y3X5|uniprotkb:Q9HAJ1|uniprotkb:Q9NV52|uniprotkb:A8K630|ensembl:ENSP00000476687 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:toip1_human(display_long)|uniprotkb:TOR1AIP1(gene name)|psi-mi:TOR1AIP1(display_short)|uniprotkb:Lamin-associated protein 1B(gene name synonym)|uniprotkb:LAP1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_056417.2|ensembl:ENSG00000143337(gene)|ensembl:ENST00000606911(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0051117"(ATPase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR008662(Lamina-associated polypeptide 1C)|interpro:IPR038599|rcsb pdb:4TVS|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001254507.1|dip:DIP-56692N - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:qFH5HTm3fcIwmGL486H8IqZHG489606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q13724 intact:EBI-25475871 intact:EBI-720141|uniprotkb:Q17RN9|uniprotkb:Q8TCT5|uniprotkb:A8K938|ensembl:ENSP00000410992|uniprotkb:F5H6D0 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mogs_human(display_long)|uniprotkb:Processing A-glucosidase I(gene name synonym)|uniprotkb:MOGS(gene name)|psi-mi:MOGS(display_short)|uniprotkb:GCS1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001139630.1|refseq:NP_006293.2|ensembl:ENSG00000115275(gene)|ensembl:ENST00000448666(transcript)|go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0015926"(glucosidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|mint:Q13724|reactome:R-HSA-4793954|reactome:R-HSA-532668|reactome:R-HSA-9683686|reactome:R-HSA-9694548 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:odbL3NUcP483ilKg/CMVn2GtdVs9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:Q12907 intact:EBI-25475871 intact:EBI-3915406|uniprotkb:Q53HH1|ensembl:ENSP00000303366 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lman2_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)|uniprotkb:C5orf8(gene name synonym)|uniprotkb:Glycoprotein GP36b(gene name synonym)|uniprotkb:Lectin mannose-binding 2(gene name synonym)|uniprotkb:Vesicular integral-membrane protein 36(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_006807.1|ensembl:ENSG00000169223(gene)|ensembl:ENST00000303127(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035664|mint:Q12907|reactome:R-HSA-204005|reactome:R-HSA-5694530 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:goqUZGW9/lvVMWDAZS9csH3TqWY9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P63218 intact:EBI-25475871 intact:EBI-10220734|uniprotkb:Q5VX54|uniprotkb:B2R5A0|uniprotkb:P30670|uniprotkb:Q61015|intact:EBI-28967048|ensembl:ENSP00000359675|ensembl:ENSP00000359679 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gbg5_human(display_long)|uniprotkb:GNG5(gene name)|psi-mi:GNG5(display_short)|uniprotkb:GNGT5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000359675|ensembl:ENSP00000359679|refseq:NP_005265.1|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENSG00000174021(gene)|ensembl:ENST00000370641(transcript)|ensembl:ENST00000370645(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:RiKSjlVpDoFyBo8J1dD238/ju589606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P62873 intact:EBI-25475871 intact:EBI-357130|ensembl:ENSP00000367872|ensembl:ENSP00000481878|uniprotkb:P04901|uniprotkb:P04697|uniprotkb:B1AJZ7|uniprotkb:Q1RMY8 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gbb1_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62873|rcsb pdb:4KFM|rcsb pdb:4PNK|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6KPF|rcsb pdb:6KPG|go:"GO:1903561"(extracellular vesicle)|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7CX3|rcsb pdb:7EB2|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-381676|reactome:R-HSA-381753|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENST00000610897(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|ensembl:ENSG00000078369(gene)|ensembl:ENST00000378609(transcript)|refseq:NP_001269467.1|refseq:NP_001269468.1|dip:DIP-599N|refseq:NP_002065.1|refseq:XP_016856548.1|refseq:XP_016856549.1|refseq:XP_016856550.1 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:zP/G70MXiSQpzbyyWFTWrJFQENk9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P62820 intact:EBI-25475871 intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286|ensembl:ENSP00000497078 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_004152.1|refseq:NP_056358.1|ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0019068"(virion assembly)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045296"(cadherin binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-1063N - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P61586 intact:EBI-25475871 intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175|ensembl:ENSP00000408402|ensembl:ENSP00000503282|ensembl:ENSP00000504180 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001655.1|refseq:NP_001300870.1|dip:DIP-29642N|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|rcsb pdb:3LW8|ensembl:ENSG00000067560(gene)|ensembl:ENST00000418115(transcript)|ensembl:ENST00000445425(transcript)|ensembl:ENST00000678200(transcript)|ensembl:ENST00000679208(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007015"(actin filament organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0017022"(myosin binding)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0001998"(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033688"(regulation of osteoblast proliferation)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0002363"(alpha-beta T cell lineage commitment)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043366"(beta selection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060193"(positive regulation of lipase activity)|go:"GO:0061383"(trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902766"(skeletal muscle satellite cell migration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904695"(positive regulation of vascular associated smooth muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:2RGN|rcsb pdb:3KZ1|go:"GO:0050919"(negative chemotaxis) - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P61106 intact:EBI-25475871 intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_057406.2|ensembl:ENSG00000119396(gene)|ensembl:ENST00000373840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P61026 intact:EBI-25475871 intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium) - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P61019 intact:EBI-25475871 intact:EBI-752037|uniprotkb:P08886|uniprotkb:B2R5W8|uniprotkb:B4DMQ5|ensembl:ENSP00000262646 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab2a_human(display_long)|uniprotkb:RAB2A(gene name)|psi-mi:RAB2A(display_short)|uniprotkb:RAB2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_002856.1|refseq:NP_001229573.1|dip:DIP-316N|ensembl:ENSG00000104388(gene)|ensembl:ENST00000262646(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1Z0A|reactome:R-HSA-162658|reactome:R-HSA-8873719 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:MyG011KOkAtsvE2hU/fs21CEe/M9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P61006 intact:EBI-25475871 intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005361.2|dip:DIP-43703N|ensembl:ENSG00000167461(gene)|ensembl:ENST00000300935(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P51149 intact:EBI-25475871 intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P51148 intact:EBI-25475871 intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689|ensembl:ENSP00000377440 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|refseq:NP_001238968.1|ensembl:ENSG00000108774(gene)|ensembl:ENST00000346213(transcript)|ensembl:ENST00000393860(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P21964 intact:EBI-25475871 intact:EBI-372265|uniprotkb:Q6IB07|uniprotkb:Q6ICE6|uniprotkb:A8MPV9|intact:EBI-743305|uniprotkb:Q9BWC7|intact:EBI-11576026|ensembl:ENSP00000354511|ensembl:ENSP00000384654|ensembl:ENSP00000385150|ensembl:ENSP00000385917|ensembl:ENSP00000503583|ensembl:ENSP00000503719|ensembl:ENSP00000504402 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:comt_human(display_long)|uniprotkb:COMT(gene name)|psi-mi:COMT(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_000745.1|refseq:NP_001128633.1|refseq:NP_001128634.1|refseq:NP_009294.1|refseq:XP_016884083.1|refseq:XP_016884084.1|ensembl:ENSG00000093010(gene)|ensembl:ENST00000361682(transcript)|ensembl:ENST00000403710(transcript)|ensembl:ENST00000406520(transcript)|ensembl:ENST00000407537(transcript)|ensembl:ENST00000676678(transcript)|ensembl:ENST00000678255(transcript)|ensembl:ENST00000678868(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0007614"(short-term memory)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0016206"(catechol O-methyltransferase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032259"(methylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032502"(developmental process)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042424"(catecholamine catabolic process)|go:"GO:0042493"|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043627"(response to estrogen)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0048265"(response to pain)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050668"(positive regulation of homocysteine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102084"(L-dopa O-methyltransferase activity)|go:"GO:0102938"(orcinol O-methyltransferase activity)|interpro:IPR002935(O-methyltransferase, family 3)|interpro:IPR017128(Catechol O-methyltransferase, eukaryotic)|interpro:IPR029063|mint:P21964|rcsb pdb:3A7E|rcsb pdb:3BWM|rcsb pdb:3BWY|rcsb pdb:4PYI|rcsb pdb:4PYJ|rcsb pdb:4PYK|rcsb pdb:4XUD|rcsb pdb:4XUE|rcsb pdb:5LSA|rcsb pdb:6I3C|rcsb pdb:6I3D|reactome:R-HSA-156581|reactome:R-HSA-379397|reactome:R-HSA-379398|reactome:R-HSA-9679191|rcsb pdb:4XUC - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:3Fnq8iVqPpOWNX6QQuiNRSsTFN09606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P11233 intact:EBI-25475871 intact:EBI-1036803|uniprotkb:A4D1W3|ensembl:ENSP00000005257 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rala_human(display_long)|uniprotkb:RAL(gene name synonym)|uniprotkb:RALA(gene name)|psi-mi:RALA(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005393.2|refseq:XP_006715825.1|go:"GO:0019003"(GDP binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051665"(membrane raft localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:1UAD|rcsb pdb:1ZC3|rcsb pdb:1ZC4|rcsb pdb:2A78|mint:P11233|rcsb pdb:2A9K|rcsb pdb:2BOV|rcsb pdb:6P0I|rcsb pdb:6P0J|rcsb pdb:6P0K|rcsb pdb:6P0L|rcsb pdb:6P0M|rcsb pdb:6P0N|rcsb pdb:6P0O|reactome:R-HSA-1445148|reactome:R-HSA-171007|reactome:R-HSA-8950505|ensembl:ENSG00000006451(gene)|ensembl:ENST00000005257(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0017022"(myosin binding)|go:"GO:0017157"(regulation of exocytosis)|refseq:XP_011513768.1 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:41WF1UoYnYZvwC0OPpYwCEqIg2E9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:P00387 intact:EBI-25475871 intact:EBI-1046040|uniprotkb:O75675|uniprotkb:Q8TDL8|uniprotkb:Q8WTS8|uniprotkb:Q9UEN4|uniprotkb:Q9UEN5|uniprotkb:Q9UL55|uniprotkb:Q9UL56|uniprotkb:B1AHF2|uniprotkb:B7Z7L3|ensembl:ENSP00000338461 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nb5r3_human(display_long)|uniprotkb:Diaphorase-1(gene name synonym)|uniprotkb:CYB5R3(gene name)|psi-mi:CYB5R3(display_short)|uniprotkb:DIA1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001165132.1|refseq:NP_000389.1|refseq:NP_001123291.1|refseq:NP_015565.1|refseq:NP_001165131.1|ensembl:ENSG00000100243(gene)|ensembl:ENST00000352397(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043531"(ADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|mint:P00387|rcsb pdb:1M91|rcsb pdb:1UMK|reactome:R-HSA-196836|reactome:R-HSA-211945|reactome:R-HSA-6798695|interpro:IPR039261|dip:DIP-50463N - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:Q8JTO6AXZ8LE4FXZAzOw2p4b6HY9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:O00116 intact:EBI-25475871 intact:EBI-2838732|uniprotkb:A5D8U9|uniprotkb:Q2TU35|ensembl:ENSP00000264167 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:adas_human(display_long)|uniprotkb:AGPS(gene name)|psi-mi:AGPS(display_short)|uniprotkb:Aging-associated gene 5 protein(gene name synonym)|uniprotkb:Alkylglycerone-phosphate synthase(gene name synonym)|uniprotkb:AAG5(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_003650.1|ensembl:ENSG00000018510(gene)|ensembl:ENST00000264167(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008609"(alkylglycerone-phosphate synthase activity)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR025650|interpro:IPR036318|mint:O00116|reactome:R-HSA-75896|reactome:R-HSA-9033241|reactome:R-HSA-9033500|interpro:IPR016166(FAD-binding, type 2) - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:P8f6+j/f+WID0lFZnLIvVN5OSzM9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:O95573 intact:EBI-25475871 intact:EBI-1190822|uniprotkb:Q60I92|uniprotkb:Q8IUM9|ensembl:ENSP00000350012|ensembl:ENSP00000375918|ensembl:ENSP00000504861|ensembl:ENSP00000504907|ensembl:ENSP00000505400|ensembl:ENSP00000505654|ensembl:ENSP00000505793|ensembl:ENSP00000505856|ensembl:ENSP00000505940|ensembl:ENSP00000506361|ensembl:ENSP00000506468|intact:EBI-21359981 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:acsl3_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:ACSL3(gene name)|psi-mi:ACSL3(display_short)|uniprotkb:ACS3(gene name synonym)|uniprotkb:FACL3(gene name synonym)|uniprotkb:LACS3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase 3(gene name synonym)|uniprotkb:Medium-chain acyl-CoA ligase Acsl3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_004448.2|refseq:NP_976251.1|refseq:XP_016859073.1|ensembl:ENSG00000123983(gene)|ensembl:ENST00000357430(transcript)|ensembl:ENST00000392066(transcript)|ensembl:ENST00000679514(transcript)|ensembl:ENST00000679558(transcript)|ensembl:ENST00000680147(transcript)|ensembl:ENST00000680251(transcript)|ensembl:ENST00000680395(transcript)|ensembl:ENST00000680684(transcript)|ensembl:ENST00000680921(transcript)|ensembl:ENST00000681383(transcript)|ensembl:ENST00000681697(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|mint:O95573|reactome:R-HSA-434313|reactome:R-HSA-75876 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:L5tCBPOlL45uh0aUFi4algZQ5nY9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449625 uniprotkb:O43169 intact:EBI-25475871 intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8 psi-mi:p0dtd1-pro_0000449625(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375744|imex:IM-28441-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2 - chain-seq-start:3860|chain-seq-end:3942 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:3AF/ThDr7adqPPYFWsiWQE2FVyY2697049 rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606 rigid:6C0a5GINtiVx67scNPxC7gC0mDU false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q9HD40 intact:EBI-25475874 intact:EBI-6163446|uniprotkb:A8K8W1|uniprotkb:Q0D2P3|uniprotkb:Q17RT1|uniprotkb:Q9NXZ5|uniprotkb:Q9UGM9|uniprotkb:Q9Y353|ensembl:ENSP00000371535 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:spcs_human(display_long)|uniprotkb:SEPSECS(gene name)|psi-mi:SEPSECS(display_short)|uniprotkb:Liver-pancreas antigen(gene name synonym)|uniprotkb:SLA-p35(gene name synonym)|uniprotkb:SLA/LP autoantigen(gene name synonym)|uniprotkb:Selenocysteine synthase(gene name synonym)|uniprotkb:"Selenocysteinyl-tRNA(Sec) synthase"(gene name synonym)|uniprotkb:"Sep-tRNA:Sec-tRNA synthase"(gene name synonym)|uniprotkb:Soluble liver antigen(gene name synonym)|uniprotkb:TRNP48(gene name synonym)|uniprotkb:UGA suppressor tRNA-associated protein(gene name synonym)|uniprotkb:"tRNA(Ser/Sec)-associated antigenic protein"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011512148.1|refseq:XP_011512150.1|refseq:NP_058651.3|ensembl:ENSG00000109618(gene)|ensembl:ENST00000382103(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001514"(selenocysteine incorporation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|go:"GO:0098621"(phosphoseryl-selenocysteinyl-tRNA selenium transferase activity)|interpro:IPR008829(Soluble liver antigen/liver pancreas antigen)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019793|interpro:IPR019872|mint:Q9HD40|rcsb pdb:3HL2|rcsb pdb:4ZDL|rcsb pdb:4ZDO|rcsb pdb:4ZDP|reactome:R-HSA-2408557 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:1xxyUK7bIUrg8CrosJ+/gdX8nXw9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q9BSC4 intact:EBI-25475874 intact:EBI-7001376|uniprotkb:Q53RC9|uniprotkb:Q9H855|uniprotkb:Q96TA5|uniprotkb:Q9H7Y7|uniprotkb:A8K3R5|intact:MINT-3060916|uniprotkb:B4DLV0|ensembl:ENSP00000371101 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nol10_human(display_long)|uniprotkb:NOL10(gene name)|psi-mi:NOL10(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_079170.2|refseq:NP_001248323.1|refseq:NP_001248321.1|ensembl:ENSG00000115761(gene)|ensembl:ENST00000381685(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012580(NUC153)|interpro:IPR036322|interpro:IPR040382|mint:Q9BSC4 - chain-seq-start:3943|chain-seq-end:4140 comment:mint figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:PiblslntTRSvRQnk82fSgtVJbXE9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q92552 intact:EBI-25475874 intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q13868 intact:EBI-25475874 intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:P82675 intact:EBI-25475874 intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS5m(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_114108.1|ensembl:ENSG00000144029(gene)|ensembl:ENST00000272418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6RW5|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q9Y399 intact:EBI-25475874 intact:EBI-2880048|intact:EBI-28977422|ensembl:ENSP00000241600|ensembl:ENSP00000360850|uniprotkb:Q5T899|uniprotkb:Q9BSQ4 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rt02_human(display_long)|uniprotkb:MRPS2(gene name)|psi-mi:MRPS2(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:CGI-91(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6RW5|ensembl:ENST00000241600(transcript)|ensembl:ENST00000371785(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0061668"(mitochondrial ribosome assembly)|ensembl:ENSG00000122140(gene)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|mint:Q9Y399|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|ensembl:ENSP00000241600|ensembl:ENSP00000360850|refseq:NP_057118.1 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:tlWj8Un0CmbnBQtZMYlJpvIpc/09606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q9ULT8 intact:EBI-25475874 intact:EBI-310559|uniprotkb:Q6P445|uniprotkb:Q86VJ1|uniprotkb:Q96F34|uniprotkb:Q9UFZ7|uniprotkb:D3DS86|ensembl:ENSP00000382269|ensembl:ENSP00000450697 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hecd1_human(display_long)|uniprotkb:HECTD1(gene name)|psi-mi:HECTD1(display_short)|uniprotkb:KIAA1131(gene name synonym)|uniprotkb:HECT domain-containing protein 1(gene name synonym)|uniprotkb:E3 ligase for inhibin receptor(gene name synonym)|uniprotkb:EULIR(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000092148(gene)|ensembl:ENST00000399332(transcript)|ensembl:ENST00000553700(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010606(Mib-herc2)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020683|interpro:IPR035983|interpro:IPR036770|interpro:IPR037252|interpro:IPR041200|mint:Q9ULT8|rcsb pdb:2DK3|rcsb pdb:3DKM|reactome:R-HSA-983168|rcsb pdb:2LC3|refseq:XP_005267559.2|ensembl:ENSP00000382269|ensembl:ENSP00000450697|refseq:NP_056197.3|dip:DIP-31669N - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:/l60ZSm+P4Vlc8B79wS7+T1Zvzk9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q9NY61 intact:EBI-25475874 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q9NQT5 intact:EBI-25475874 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q9NQT4 intact:EBI-25475874 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q9H6F5 intact:EBI-25475874 intact:EBI-721289|uniprotkb:B4DY99|ensembl:ENSP00000227520 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ccd86_human(display_long)|uniprotkb:Cytokine-induced protein with coiled-coil domain(gene name synonym)|uniprotkb:CYCLON(gene name synonym)|uniprotkb:CCDC86(gene name)|psi-mi:CCDC86(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_077003.1|ensembl:ENSG00000110104(gene)|ensembl:ENST00000227520(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR005579(Cgr1)|interpro:IPR026570|mint:Q9H6F5 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:dRd5UWPzAehh8OFqkWrMMCnYYug9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q96I59 intact:EBI-25475874 intact:EBI-5455236|uniprotkb:G3V178|ensembl:ENSP00000281038 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:synm_human(display_long)|uniprotkb:NARS2(gene name)|psi-mi:NARS2(display_short)|uniprotkb:Asparaginyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_078954.4|refseq:NP_001230180.1|refseq:XP_016873792.1|ensembl:ENSG00000137513(gene)|ensembl:ENST00000281038(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004816"(asparagine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006421"(asparaginyl-tRNA aminoacylation)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004522(Asparaginyl-tRNA synthetase, class IIb)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-HSA-379726 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:8r61DYTijthPntztWKOxzbklcPY9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q96B26 intact:EBI-25475874 intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:y/cReHiPMubzNruyETohBjbRick9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q8NEJ9 intact:EBI-25475874 intact:EBI-9995414|uniprotkb:A8K760|uniprotkb:Q9Y400|ensembl:ENSP00000386134 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ngdn_human(display_long)|uniprotkb:NGDN(gene name)|psi-mi:NGDN(display_short)|uniprotkb:C14orf120(gene name synonym)|uniprotkb:Centromere accumulated nuclear protein 1(gene name synonym)|uniprotkb:EIF4E-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001036100.1|refseq:NP_056329.1|ensembl:ENSG00000129460(gene)|ensembl:ENST00000408901(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006417"(regulation of translation)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032040"(small-subunit processome)|interpro:IPR007146(Small-subunit processome, Utp3)|mint:Q8NEJ9 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:dzn7QntKCrb97VLlmUMizp+0CV49606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q7L2J0 intact:EBI-25475874 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q4G0J3 intact:EBI-25475874 intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-2560173|ensembl:ENSP00000314311|ensembl:ENSP00000344950|ensembl:ENSP00000499190 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_056269.1|refseq:NP_057732.2|refseq:NP_001253968.1|dip:DIP-47624N|ensembl:ENSG00000174720(gene)|ensembl:ENST00000324052(transcript)|ensembl:ENST00000344442(transcript)|ensembl:ENST00000651579(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:Q13206 intact:EBI-25475874 intact:EBI-2514399|ensembl:ENSP00000314348|uniprotkb:Q5BJD8|uniprotkb:B2RCQ3 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ddx10_human(display_long)|uniprotkb:DDX10(gene name)|psi-mi:DDX10(display_short)|uniprotkb:DEAD box protein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000178105(gene)|ensembl:ENST00000322536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0097065"(anterior head development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|mint:Q13206|rcsb pdb:2PL3|refseq:NP_004389.2 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:MMAbABrYQHlYDyPsagT7oY92Z3M9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:P82663 intact:EBI-25475874 intact:EBI-1046734|uniprotkb:Q9H7P5|ensembl:ENSP00000253686|uniprotkb:B4DFJ5|uniprotkb:B4DQG6 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rt25_human(display_long)|uniprotkb:MRPS25(gene name)|psi-mi:MRPS25(display_short)|uniprotkb:RPMS25(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS25(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_071942.1|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000131368(gene)|ensembl:ENST00000253686(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR040049|mint:P82663|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:DQMtBaQJW2Ic025zsKJYfN4aj1I9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:P61011 intact:EBI-25475874 intact:EBI-2854176|uniprotkb:B2R759|uniprotkb:P13624|uniprotkb:B4DUW6|ensembl:ENSP00000216774|ensembl:ENSP00000451818|ensembl:ENSP00000504518|ensembl:ENSP00000504673 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:srp54_human(display_long)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:XP_011535408.1|refseq:NP_001139754.1|refseq:NP_003127.1|ensembl:ENSG00000100883(gene)|ensembl:ENST00000678963(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019003"(GDP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|mint:P61011|rcsb pdb:1MFQ|rcsb pdb:1QB2|rcsb pdb:5L3Q|rcsb pdb:6Y2Z|rcsb pdb:6Y30|rcsb pdb:6Y31|rcsb pdb:6Y32|rcsb pdb:7NFX|ensembl:ENST00000216774(transcript)|reactome:R-HSA-1799339|ensembl:ENST00000556994(transcript)|ensembl:ENST00000677647(transcript) - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:8iRlU+NvhLEJNv7B90TAZyRqwiY9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:P09132 intact:EBI-25475874 intact:EBI-2680090|uniprotkb:B2R4E9|uniprotkb:Q96FG6|uniprotkb:Q05D77|uniprotkb:D6RCQ5|ensembl:ENSP00000424870 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:srp19_human(display_long)|uniprotkb:SRP19(gene name)|psi-mi:SRP19(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001191123.1|refseq:NP_003126.1|refseq:NP_001191122.1|refseq:NP_001191125.1|ensembl:ENSG00000153037(gene)|ensembl:ENST00000505459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR036521|mint:P09132|rcsb pdb:1JID|rcsb pdb:1MFQ|rcsb pdb:1RY1|rcsb pdb:2J37|rcsb pdb:3KTV|rcsb pdb:4P3E|rcsb pdb:5M73|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-41412N - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:yIFmf1q6m2wQt3eaiCc1dlIQXn89606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:O96028 intact:EBI-25475874 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:O95260 intact:EBI-25475874 intact:EBI-1043378|uniprotkb:O95261|uniprotkb:Q8WW04|ensembl:ENSP00000224652|uniprotkb:Q5SQQ3 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ate1_human(display_long)|uniprotkb:Arginine-tRNA--protein transferase 1(gene name synonym)|uniprotkb:ATE1(gene name)|psi-mi:ATE1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000107669(gene)|ensembl:ENST00000224652(transcript)|interpro:IPR007471(Arginine-tRNA-protein transferase, N-terminal)|interpro:IPR007472(Arginine-tRNA-protein transferase, C-terminal)|go:"GO:0004057"(arginyltransferase activity)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017137(Arginine-tRNA--protein transferase 1, eukaryotic)|go:"GO:0005634"(nucleus)|interpro:IPR030700|mint:O95260|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016598"(protein arginylation)|refseq:NP_001001976.1|refseq:NP_008972.2|refseq:NP_001275663.1|refseq:NP_001275664.1|refseq:NP_001275665.1 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:vK21nNxx2fa9ct7O5WG0LqtD9u09606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:O76094 intact:EBI-25475874 intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449626 uniprotkb:O00566 intact:EBI-25475874 intact:EBI-5235884|uniprotkb:A0AVJ8|ensembl:ENSP00000244230 psi-mi:p0dtd1-pro_0000449626(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mpp10_human(display_long)|uniprotkb:MPHOSPH10(gene name)|psi-mi:MPHOSPH10(display_short)|uniprotkb:MPP10(gene name synonym)|uniprotkb:M phase phosphoprotein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375785|imex:IM-28441-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005782.1|ensembl:ENSG00000124383(gene)|ensembl:ENST00000244230(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR012173(U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p)|mint:O00566|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - chain-seq-start:3943|chain-seq-end:4140 - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:Bxev1BKtZTT1Fyf+lpsPapVosnc2697049 rogid:xkz11U1x5r2joVtVq6JG4asO1Qw9606 rigid:BRJBJdwskaVDk73NjzzCJDJgrKI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:P35556 intact:EBI-25475877 intact:EBI-6164392|ensembl:ENSP00000424571|ensembl:ENSP00000262464|uniprotkb:B4DU01|uniprotkb:Q59ES6 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fbn2_human(display_long)|uniprotkb:FBN2(gene name)|psi-mi:FBN2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35556|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|interpro:IPR018097|ensembl:ENSG00000138829(gene)|ensembl:ENST00000262464(transcript)|ensembl:ENST00000508053(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|refseq:NP_001990.2 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:iqBnjHuy9kU3serIc5tPWGIDzUc9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q9UBX5 intact:EBI-25475877 intact:EBI-947897|uniprotkb:O75966|uniprotkb:Q6UWA3|uniprotkb:Q6IAL4|ensembl:ENSP00000345008 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fbln5_human(display_long)|uniprotkb:Developmental arteries and neural crest EGF-like protein(gene name synonym)|uniprotkb:Urine p50 protein(gene name synonym)|uniprotkb:FBLN5(gene name)|psi-mi:FBLN5(display_short)|uniprotkb:DANCE(gene name synonym)|uniprotkb:UNQ184/PRO210(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_006320.2|dip:DIP-44301N|ensembl:ENSG00000140092(gene)|ensembl:ENST00000342058(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000121"(regulation of removal of superoxide radicals)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR018097|interpro:IPR026823|interpro:IPR037288|mint:Q9UBX5|reactome:R-HSA-1566948|reactome:R-HSA-2129379 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:1fqx+PBkfO9F1/5wXcNasL9R8Mk9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q9NZL9 intact:EBI-25475877 intact:EBI-10317491|uniprotkb:B2R5Y6|uniprotkb:Q6NYC7|uniprotkb:Q27J92|uniprotkb:Q9BS89|uniprotkb:Q9H3E1|uniprotkb:Q3LIE8|uniprotkb:Q9UJ54|uniprotkb:Q1WAI7|uniprotkb:Q567T7|ensembl:ENSP00000325425 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mat2b_human(display_long)|uniprotkb:MAT2B(gene name)|psi-mi:MAT2B(display_short)|uniprotkb:Methionine adenosyltransferase II beta(gene name synonym)|uniprotkb:Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase(gene name synonym)|uniprotkb:TGR(gene name synonym)|uniprotkb:MSTP045(orf name)|uniprotkb:Nbla02999(orf name)|uniprotkb:UNQ2435/PRO4995(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_037415.1|refseq:NP_877725.1|ensembl:ENSG00000038274(gene)|ensembl:ENST00000321757(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0048270"(methionine adenosyltransferase regulator activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005913(dTDP-4-dehydrorhamnose reductase)|interpro:IPR029903|interpro:IPR036291|rcsb pdb:2YDX|rcsb pdb:2YDY|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|reactome:R-HSA-156581|reactome:R-HSA-5689880 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:RxXcRktcrFe+9xm7qgSyZoci4rU9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q9BVL2 intact:EBI-25475877 intact:EBI-2811583|uniprotkb:O43160|uniprotkb:Q5JRG5|uniprotkb:Q5JRG2|uniprotkb:A6NI12|uniprotkb:B4DZJ1|ensembl:ENSP00000371155 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nup58_human(display_long)|uniprotkb:NUP58(gene name)|psi-mi:NUP58(display_short)|uniprotkb:58 kDa nucleoporin(gene name synonym)|uniprotkb:KIAA0410(gene name synonym)|uniprotkb:NUPL1(gene name synonym)|uniprotkb:Nucleoporin-like protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001008564.1|refseq:NP_054808.1|ensembl:ENST00000381718|ensembl:ENSP00000371137|ensembl:ENSP00000371155|ensembl:ENST00000463407|ensembl:ENSP00000418555|ensembl:ENSG00000139496(gene)|ensembl:ENST00000381736(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR024882|rcsb pdb:4JO7|rcsb pdb:4JO9|rcsb pdb:4JQ5|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9609690 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:r5XY6QyOFxuZgJjeuVPoLag3YNI9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q99567 intact:EBI-25475877 intact:EBI-726178|uniprotkb:Q9BWE5|uniprotkb:D3DTM2|intact:EBI-28967918|ensembl:ENSP00000458954 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nup88_human(display_long)|uniprotkb:Nucleoporin Nup88(gene name synonym)|uniprotkb:88 kDa nucleoporin(gene name synonym)|uniprotkb:NUP88(gene name)|psi-mi:NUP88(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000458954|refseq:NP_002523.2|refseq:NP_001307582.1|ensembl:ENSG00000108559(gene)|ensembl:ENST00000573584(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005215"(transporter activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|interpro:IPR019321|interpro:IPR037700|mint:Q99567|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:4e7YTurNWkXUn9zj0JiD2muc94A9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q96F45 intact:EBI-25475877 intact:EBI-8832437|uniprotkb:Q96E25|uniprotkb:Q8NAC5|uniprotkb:Q96IJ0|ensembl:ENSP00000361602 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zn503_human(display_long)|uniprotkb:NOLZ1(gene name synonym)|uniprotkb:ZNF503(gene name)|psi-mi:ZNF503(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_116161.2|ensembl:ENSG00000165655(gene)|ensembl:ENST00000372524(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070315"(G1 to G0 transition involved in cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022129 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:NpN+RnNBhDISreteXZIxozWoURI9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q8TD19 intact:EBI-25475877 intact:EBI-1044009|uniprotkb:Q52LK6|uniprotkb:Q8NCN0|uniprotkb:Q8TCY4|uniprotkb:Q9UPI4|uniprotkb:Q9Y6S4|uniprotkb:Q9Y6S5|uniprotkb:Q9Y6S6|intact:EBI-28978800|ensembl:ENSP00000238616 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nek9_human(display_long)|uniprotkb:NEK9(gene name)|psi-mi:NEK9(display_short)|uniprotkb:KIAA1995(gene name synonym)|uniprotkb:NEK8(gene name synonym)|uniprotkb:NERCC(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 9(gene name synonym)|uniprotkb:Nercc1 kinase(gene name synonym)|uniprotkb:NimA-related kinase 8(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_149107.4|ensembl:ENSG00000119638(gene)|ensembl:ENST00000238616(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011009(Protein kinase-like)|interpro:IPR042767|mint:Q8TD19|rcsb pdb:3ZKE|rcsb pdb:3ZKF|reactome:R-HSA-2980767|reactome:R-HSA-3301854|reactome:R-HSA-9648025|ensembl:ENSP00000238616|refseq:NP_001316166.1|refseq:NP_001316167.1 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:nH92Hku490dDttw5Akug+NjXRNY9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q8N0X7 intact:EBI-25475877 intact:EBI-2643803|uniprotkb:Q9H1T3|uniprotkb:Q9H1T2|uniprotkb:O60349|uniprotkb:Q86Y67|ensembl:ENSP00000347314|ensembl:ENSP00000406061|ensembl:ENSP00000414147|ensembl:ENSP00000473599|ensembl:ENSP00000497209 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:spart_human(display_long)|uniprotkb:SPART(gene name)|psi-mi:SPART(display_short)|uniprotkb:KIAA0610(gene name synonym)|uniprotkb:SPG20(gene name synonym)|uniprotkb:Spastic paraplegia 20 protein(gene name synonym)|uniprotkb:TAHCCP1(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_001135766.1|refseq:NP_001135767.1|refseq:NP_001135768.1|refseq:NP_055902.1|refseq:XP_011533314.1|refseq:XP_005266370.1|refseq:XP_005266371.1|refseq:XP_005266372.1|ensembl:ENSG00000133104(gene)|ensembl:ENST00000355182(transcript)|ensembl:ENST00000438666(transcript)|ensembl:ENST00000451493(transcript)|ensembl:ENST00000494062(transcript)|ensembl:ENST00000650221(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009838"(abscission)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0048698"(negative regulation of collateral sprouting in absence of injury)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051301"(cell division)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060612"(adipose tissue development)|interpro:IPR007330(MIT)|interpro:IPR009686(Senescence-associated)|interpro:IPR036181|rcsb pdb:2DL1|rcsb pdb:4U7I|go:"GO:0030514"(negative regulation of BMP signaling pathway)|refseq:XP_005266374.1 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:Km2bYRg7JLYy7voEgYVdAHZhzE09606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q86YT6 intact:EBI-25475877 intact:EBI-2129148|uniprotkb:Q2TB37|uniprotkb:Q68D01|uniprotkb:Q6YI51|uniprotkb:Q8NBY0|uniprotkb:Q8TCB5|uniprotkb:Q8TCL7|uniprotkb:Q9P2M3|uniprotkb:B0YJ38|ensembl:ENSP00000261537 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mib1_human(display_long)|uniprotkb:MIB1(gene name)|psi-mi:MIB1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:KIAA1323(gene name synonym)|uniprotkb:ZZANK2(gene name synonym)|uniprotkb:Mind bomb homolog 1(gene name synonym)|uniprotkb:DAPK-interacting protein 1(gene name synonym)|uniprotkb:Zinc finger ZZ type with ankyrin repeat domain protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_065825.1|ensembl:ENSG00000101752(gene)|ensembl:ENST00000261537(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001947"(heart looping)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR010606(Mib-herc2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|interpro:IPR043145|mint:Q86YT6|rcsb pdb:4TSE|rcsb pdb:4XI6|rcsb pdb:4XI7|rcsb pdb:4XIB|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:+DhNmSTvuXexGhi2FyEuBv4pBiw9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q7Z3B4 intact:EBI-25475877 intact:EBI-741048|uniprotkb:Q96EA7|uniprotkb:Q9NVL5|uniprotkb:Q9P0I1|uniprotkb:B2RCK7|intact:EBI-10966427|uniprotkb:B4DT35|ensembl:ENSP00000264883 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nup54_human(display_long)|uniprotkb:54 kDa nucleoporin(gene name synonym)|uniprotkb:NUP54(gene name)|psi-mi:NUP54(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_059122.2|refseq:NP_001265532.1|ensembl:ENSG00000138750(gene)|ensembl:ENST00000264883(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006605"(protein targeting)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q7Z3B4|rcsb pdb:4JNU|rcsb pdb:4JNV|rcsb pdb:4JO7|rcsb pdb:4JO9|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:/X2b8J20uRh86bEeCc1tJSRuaIM9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:Q15056 intact:EBI-25475877 intact:EBI-748492|uniprotkb:A8K3R1|uniprotkb:D3DXF6|uniprotkb:D3DXF8|ensembl:ENSP00000265753 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:if4h_human(display_long)|uniprotkb:Williams-Beuren syndrome chromosomal region 1 protein(gene name synonym)|uniprotkb:EIF4H(gene name)|psi-mi:EIF4H(display_short)|uniprotkb:WBSCR1(gene name synonym)|uniprotkb:KIAA0038(gene name synonym)|uniprotkb:WSCR1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_071496.1|refseq:NP_114381.1|ensembl:ENSG00000106682(gene)|ensembl:ENST00000265753(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0019953"(sexual reproduction)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034229|interpro:IPR035979|mint:Q15056|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:dNPoAzwFD5lFwCMnRl0cbXM3j8s9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:P61962 intact:EBI-25475877 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:P37198 intact:EBI-25475877 intact:EBI-347978|intact:EBI-28983799|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|uniprotkb:Q6GTM2|uniprotkb:Q503A4|uniprotkb:Q96C43|uniprotkb:Q9NSL1|uniprotkb:B3KWU5 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nup62_human(display_long)|uniprotkb:NUP62(gene name)|psi-mi:NUP62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_714941.1|ensembl:ENSG00000213024(gene)|ensembl:ENST00000352066(transcript)|ensembl:ENST00000422090(transcript)|ensembl:ENST00000596217(transcript)|ensembl:ENST00000597029(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0003682"(chromatin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:P37198|rcsb pdb:2H4D|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|refseq:NP_714940.1|refseq:NP_001180286.1|refseq:NP_036478.2|refseq:NP_057637.2|ensembl:ENSP00000305503|ensembl:ENSP00000407331|ensembl:ENSP00000471191|ensembl:ENSP00000473192|dip:DIP-29749N - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:v7mvKvTtVEnLMwcpUZIcdAzge009606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:P35658 intact:EBI-25475877 intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:P35555 intact:EBI-25475877 intact:EBI-2505934|ensembl:ENSP00000325527|uniprotkb:B2RUU0|uniprotkb:Q15972|uniprotkb:Q75N87|uniprotkb:D2JYH6 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fbn1_human(display_long)|uniprotkb:FBN1(gene name)|psi-mi:FBN1(display_short)|uniprotkb:FBN(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) ensembl:ENSG00000166147(gene)|ensembl:ENST00000316623(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001527"(microfibril)|go:"GO:0001656"(metanephros development)|go:"GO:0005178"(integrin binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0008201"(heparin binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034199"(activation of protein kinase A activity)|go:"GO:0035582"(sequestering of BMP in extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0048050"(post-embryonic eye morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2001205"(negative regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR017878|interpro:IPR018097|interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35555|rcsb pdb:1APJ|rcsb pdb:1EMN|rcsb pdb:1EMO|rcsb pdb:1LMJ|rcsb pdb:1UZJ|rcsb pdb:1UZK|rcsb pdb:1UZP|rcsb pdb:1UZQ|rcsb pdb:2M74|rcsb pdb:2W86|rcsb pdb:5MS9|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_000129.3|dip:DIP-29985N - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:YEO0ZRTezrjEAyTaos1pm2hUDXg9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD1-PRO_0000449627 uniprotkb:P13984 intact:EBI-25475877 intact:EBI-1030560|uniprotkb:A6NNS5|uniprotkb:Q5W0H3|ensembl:ENSP00000340823 psi-mi:p0dtd1-pro_0000449627(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:t2fb_human(display_long)|uniprotkb:GTF2F2(gene name)|psi-mi:GTF2F2(display_short)|uniprotkb:RAP30(gene name synonym)|uniprotkb:Transcription initiation factor IIF subunit beta(gene name synonym)|uniprotkb:ATP-dependent helicase GTF2F2(gene name synonym)|uniprotkb:Transcription initiation factor RAP30(gene name synonym)|uniprotkb:General transcription factor IIF 30 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375831|imex:IM-28441-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) refseq:NP_004119.1|ensembl:ENSG00000188342(gene)|ensembl:ENST00000340473(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003196(Transcription initiation factor IIF, beta subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR040450|interpro:IPR040504|mint:P13984|interpro:IPR036390|rcsb pdb:1BBY|rcsb pdb:1F3U|rcsb pdb:2BBY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|dip:DIP-41680N - chain-seq-start:4141|chain-seq-end:4253 - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4/ohQhJXTSeDo5Sge6OUGfwU6zo2697049 rogid:kAfbXXjVR1dmgs+WHBlTuG6AVTs9606 rigid:GpneYkoctfAoQWXnlpZ87bHGAhM false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:Q9C0D3 intact:EBI-26375873 intact:EBI-1811414|uniprotkb:Q8N2X3|uniprotkb:Q9H8L8|ensembl:ENSP00000294353 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:zy11b_human(display_long)|uniprotkb:ZYG11B(gene name)|psi-mi:ZYG11B(display_short)|uniprotkb:KIAA1730(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 refseq:NP_078922.1|ensembl:ENSG00000162378(gene)|ensembl:ENST00000294353(transcript)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|interpro:IPR040367|mint:Q9C0D3 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:PL/P806AUcYTlvB6/2VS/UxLUYg9606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:Q15370 intact:EBI-26375873 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:Q15369 intact:EBI-26375873 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:P62877 intact:EBI-26375873 intact:EBI-398523|uniprotkb:Q8N6Z8|uniprotkb:Q9D1S2|uniprotkb:Q9WUK9|uniprotkb:Q9Y254|uniprotkb:B2RDY1|ensembl:ENSP00000216225 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:rbx1_human(display_long)|uniprotkb:RBX1(gene name)|psi-mi:RBX1(display_short)|uniprotkb:RNF75(gene name synonym)|uniprotkb:ROC1(gene name synonym)|uniprotkb:Regulator of cullins 1(gene name synonym)|uniprotkb:RING finger protein 75(gene name synonym)|uniprotkb:Protein ZYP(gene name synonym)|uniprotkb:RING-box protein 1(gene name synonym)|uniprotkb:E3 ubiquitin-protein transferase RBX1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 refseq:NP_055063.1|dip:DIP-17014N|ensembl:ENSG00000100387(gene)|ensembl:ENST00000216225(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019788"(NEDD8 transferase activity)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061663"(NEDD8 ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR024766|mint:P62877|rcsb pdb:1LDJ|rcsb pdb:1LDK|rcsb pdb:1U6G|rcsb pdb:2HYE|rcsb pdb:2LGV|rcsb pdb:3DPL|rcsb pdb:3DQV|rcsb pdb:3RTR|rcsb pdb:4F52|rcsb pdb:4P5O|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6TTU|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5N|rcsb pdb:7B5S|reactome:R-HSA-110314|reactome:R-HSA-1170546|reactome:R-HSA-1234176|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2894862|reactome:R-HSA-4641258|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68949|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:pSaSNRZo+QudTPXOLUlksOj3smM9606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:Q9Y5J9 intact:EBI-26375873 intact:EBI-1049085|uniprotkb:Q3KQS9|uniprotkb:Q9UN04|uniprotkb:B0YJA5|ensembl:ENSP00000422122 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:tim8b_human(display_long)|uniprotkb:Deafness dystonia protein 2(gene name synonym)|uniprotkb:DDP-like protein(gene name synonym)|uniprotkb:TIM8B(gene name synonym)|uniprotkb:TIMM8B(gene name)|psi-mi:TIMM8B(display_short)|uniprotkb:DDP2(gene name synonym)|uniprotkb:DDPL(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 refseq:NP_036591.2|ensembl:ENSG00000150779(gene)|ensembl:ENST00000504148(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0140318"(protein transporter activity)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5J9|reactome:R-HSA-1268020 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:7DK/1BIkwyl9KMIgEFWqRhZn2ZE9606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:Q9BU02 intact:EBI-26375873 intact:EBI-2820864|uniprotkb:G3V4J3|uniprotkb:D3DS50|ensembl:ENSP00000288014|ensembl:ENSP00000384580 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:thtpa_human(display_long)|uniprotkb:THTPA(gene name)|psi-mi:THTPA(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 refseq:NP_001119811.1|refseq:NP_077304.1|refseq:NP_001242991.1|refseq:NP_001243250.1|refseq:NP_001243251.1|refseq:NP_001243252.1|ensembl:ENSG00000259431(gene)|ensembl:ENST00000288014(transcript)|ensembl:ENST00000404535(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042357"(thiamine diphosphate metabolic process)|go:"GO:0050333"(thiamin-triphosphatase activity)|interpro:IPR012177(Thiamine triphosphatase)|interpro:IPR023577|interpro:IPR033469|interpro:IPR039582|rcsb pdb:3BHD|rcsb pdb:3TVL|reactome:R-HSA-196819|go:"GO:0006772"(thiamine metabolic process) - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:34iJ9iQYclIaBD04IIkXNMhBOx89606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:Q3KQU3 intact:EBI-26375873 intact:EBI-713229|uniprotkb:Q9HBQ2|uniprotkb:Q8N905|uniprotkb:Q9ULN3|uniprotkb:Q7L8J5|uniprotkb:Q8TAK0|intact:EBI-2511981|intact:EBI-1056140|ensembl:ENSP00000362244|uniprotkb:Q9NW29|uniprotkb:D3DPS4 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:ma7d1_human(display_long)|uniprotkb:MAP7D1(gene name)|psi-mi:MAP7D1(display_short)|uniprotkb:KIAA1187(gene name synonym)|uniprotkb:PARCC1(gene name synonym)|uniprotkb:RPRC1(gene name synonym)|uniprotkb:Proline/arginine-rich coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:Arginine/proline-rich coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:PP2464(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 refseq:NP_001273294.1|refseq:NP_001273295.1|ensembl:ENSG00000116871(gene)|ensembl:ENST00000373151(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR008604(E-MAP-115)|mint:Q3KQU3|refseq:NP_060537.3 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:AEal3/uaJsdRBdmijI8nuthBD9k9606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:Q13617 intact:EBI-26375873 intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A6M4B8V5 uniprotkb:P50897 intact:EBI-26375873 intact:EBI-1237011|intact:EBI-2859371|uniprotkb:Q6FGQ4|uniprotkb:B4DY24|ensembl:ENSP00000432053|ensembl:ENSP00000493153 psi-mi:a0a6m4b8v5_sars2(display_long)|uniprotkb:ORF10(gene name)|psi-mi:ORF10(display_short) psi-mi:ppt1_human(display_long)|uniprotkb:PPT1(gene name)|psi-mi:PPT1(display_short)|uniprotkb:PPT(gene name synonym)|uniprotkb:Palmitoyl-protein hydrolase 1(gene name synonym)|uniprotkb:CLN1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375857|imex:IM-28441-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044342 refseq:NP_000301.1|refseq:NP_001136076.1|ensembl:ENSG00000131238(gene)|ensembl:ENST00000529905(transcript)|ensembl:ENST00000642050(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0007625"(grooming behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016790"(thiolester hydrolase activity)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031579"(membrane raft organization)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050896"(response to stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120146"(sulfatide binding)|interpro:IPR002472(Palmitoyl protein thioesterase)|interpro:IPR029058|interpro:IPR030294|mint:P50897|rcsb pdb:3GRO|reactome:R-HSA-75105|go:"GO:0043524"(negative regulation of neuron apoptotic process) - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:7Thf7AYh41AUnrzQdTSDW1NZr5s2697049 rogid:2G1ae6m4OZsMiRzro/2JmWiOOMA9606 rigid:rLFXwgeK++eX3JCP2YHkGOGPZdE false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC3 uniprotkb:Q9Y673 intact:EBI-25475894 intact:EBI-11725055|uniprotkb:B4DR37|uniprotkb:Q5TBA6|ensembl:ENSP00000239891 psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym) psi-mi:alg5_human(display_long)|uniprotkb:ALG5(gene name)|psi-mi:ALG5(display_short)|uniprotkb:Asparagine-linked glycosylation protein 5 homolog(gene name synonym)|uniprotkb:HSPC149(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375886|imex:IM-28441-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719 refseq:NP_001135836.1|refseq:NP_037470.1|ensembl:ENSG00000120697(gene)|ensembl:ENST00000239891(transcript)|go:"GO:0004576"(oligosaccharyl transferase activity)|go:"GO:0004581"(dolichyl-phosphate beta-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR035518|reactome:R-HSA-480985 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049 rogid:BrOq249TNUXkpnFulYQvYILVHUA9606 rigid:S4HoKEmJ+UJcLTg5yXZ2D+iYJrs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC3 uniprotkb:Q9UH99 intact:EBI-25475894 intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5 psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym) psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375886|imex:IM-28441-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719 refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049 rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606 rigid:S4HoKEmJ+UJcLTg5yXZ2D+iYJrs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC3 uniprotkb:Q9H270 intact:EBI-25475894 intact:EBI-373380|uniprotkb:Q8WY89|uniprotkb:Q96EP8|uniprotkb:Q9H6D9|uniprotkb:Q9HCS6|ensembl:ENSP00000479680 psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym) psi-mi:vps11_human(display_long)|uniprotkb:VPS11(gene name)|psi-mi:VPS11(display_short)|uniprotkb:PP3476(orf name)|uniprotkb:RING finger protein 108(gene name synonym)|uniprotkb:RNF108(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375886|imex:IM-28441-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719 refseq:NP_068375.3|refseq:NP_001277114.1|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016528(Vacuolar protein sorting-associated protein 11)|interpro:IPR024763|interpro:IPR036322|mint:Q9H270|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|ensembl:ENSG00000160695(gene)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENST00000620429(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005764"(lysosome)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0030897"(HOPS complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007032"(endosome organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0007033"(vacuole organization)|go:"GO:0048284"(organelle fusion)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport) - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049 rogid:jHCrh6Lc0dS37Fumbf/lTE8Y1Og9606 rigid:S4HoKEmJ+UJcLTg5yXZ2D+iYJrs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC3 uniprotkb:Q96S66 intact:EBI-25475894 intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|ensembl:ENSP00000349456|ensembl:ENSP00000358986|ensembl:ENSP00000502251|ensembl:ENSP00000502457|ensembl:ENSP00000502648|ensembl:ENSP00000502836 psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym) psi-mi:clcc1_human(display_long)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375886|imex:IM-28441-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719 refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940(gene)|ensembl:ENST00000356970(transcript)|ensembl:ENST00000369969(transcript)|ensembl:ENST00000674849(transcript)|ensembl:ENST00000675508(transcript)|ensembl:ENST00000675654(transcript)|ensembl:ENST00000675956(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR009231(Mid-1-related chloride channel) - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049 rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606 rigid:S4HoKEmJ+UJcLTg5yXZ2D+iYJrs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC3 uniprotkb:Q96JC1 intact:EBI-25475894 intact:EBI-1050197|uniprotkb:O94869|uniprotkb:Q7Z3V3|uniprotkb:Q96B93|uniprotkb:Q96RM0|uniprotkb:Q71SQ6|ensembl:ENSP00000335193 psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym) psi-mi:vps39_human(display_long)|uniprotkb:KIAA0770(gene name synonym)|uniprotkb:VPS39(gene name)|psi-mi:VPS39(display_short)|uniprotkb:VAM6(gene name synonym)|uniprotkb:TLP(gene name synonym)|uniprotkb:TRAP1-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375886|imex:IM-28441-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719 refseq:NP_056104.2|refseq:NP_001288067.1|ensembl:ENSG00000166887(gene)|ensembl:ENST00000348544(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001180(Citron-like)|interpro:IPR019452|interpro:IPR019453|interpro:IPR032914|rcsb pdb:6ZE9 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049 rogid:BeY8ZDCOyTvZqA0WpdWnmz+giYk9606 rigid:S4HoKEmJ+UJcLTg5yXZ2D+iYJrs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC3 uniprotkb:Q8N6S5 intact:EBI-25475894 intact:EBI-2808844|intact:EBI-28975285|ensembl:ENSP00000315357|uniprotkb:Q7Z4G7|uniprotkb:B2RDS6 psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym) psi-mi:ar6p6_human(display_long)|uniprotkb:ARL6IP6(gene name)|psi-mi:ARL6IP6(display_short)|uniprotkb:PFAAP1(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375886|imex:IM-28441-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719 ensembl:ENSP00000315357|ensembl:ENSG00000177917(gene)|ensembl:ENST00000326446(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR029383|mint:Q8N6S5|refseq:NP_689735.1 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049 rogid:UrQYB2/lPYvIbJ0LgJTWbJI1//Q9606 rigid:S4HoKEmJ+UJcLTg5yXZ2D+iYJrs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC3 uniprotkb:P09601 intact:EBI-25475894 intact:EBI-2806151|ensembl:ENSP00000216117 psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym) psi-mi:hmox1_human(display_long)|uniprotkb:HO(gene name synonym)|uniprotkb:HO1(gene name synonym)|uniprotkb:HMOX1(gene name)|psi-mi:HMOX1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375886|imex:IM-28441-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719 rcsb pdb:6EHA|reactome:R-HSA-189483|reactome:R-HSA-6785807|reactome:R-HSA-844456|reactome:R-HSA-917937|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-9707564|reactome:R-HSA-9707587|reactome:R-HSA-9707616|refseq:NP_002124.1|ensembl:ENSG00000100292(gene)|ensembl:ENST00000216117(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002246"(wound healing involved in inflammatory response)|go:"GO:0002686"(negative regulation of leukocyte migration)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006788"(heme oxidation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007588"(excretion)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008219"(cell death)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034395"(regulation of transcription from RNA polymerase II promoter in response to iron)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0043627"(response to estrogen)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|rcsb pdb:1N3U|rcsb pdb:1N45|rcsb pdb:1NI6|rcsb pdb:1OYK|rcsb pdb:1OYL|rcsb pdb:1OZE|rcsb pdb:1OZL|rcsb pdb:1OZR|rcsb pdb:1OZW|rcsb pdb:1S13|rcsb pdb:1S8C|rcsb pdb:1T5P|rcsb pdb:1TWN|rcsb pdb:1TWR|rcsb pdb:1XJZ|rcsb pdb:1XK0|rcsb pdb:1XK1|rcsb pdb:1XK2|rcsb pdb:1XK3|rcsb pdb:3CZY|rcsb pdb:3HOK|rcsb pdb:3K4F|rcsb pdb:3TGM|rcsb pdb:4WD4|rcsb pdb:5BTQ|go:"GO:0042167"(heme catabolic process) - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049 rogid:Qrwo0mQGREIpHf3DLrvyO6DOLKM9606 rigid:S4HoKEmJ+UJcLTg5yXZ2D+iYJrs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC3 uniprotkb:Q8IWR1 intact:EBI-25475894 intact:EBI-10262539|uniprotkb:A8K5G9|uniprotkb:D3DNL9|intact:EBI-28978637|ensembl:ENSP00000311219 psi-mi:ap3a_sars2(display_long)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)|uniprotkb:Protein 3a(gene name synonym) psi-mi:tri59_human(display_long)|uniprotkb:TRIM59(gene name)|psi-mi:TRIM59(display_short)|uniprotkb:RING finger protein 104(gene name synonym)|uniprotkb:RNF104(gene name synonym)|uniprotkb:TRIM57(gene name synonym)|uniprotkb:TSBF1(gene name synonym)|uniprotkb:Tumor suppressor TSBF-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375886|imex:IM-28441-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0044174"(host cell endosome)|go:"GO:0044187"(host cell lysosome)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|rcsb pdb:7KJR|refseq:YP_009724391.1|rcsb pdb:6XDC|reactome:R-HSA-9694322|reactome:R-HSA-9694614|reactome:R-HSA-9694635|reactome:R-HSA-9694719 ensembl:ENSP00000311219|refseq:NP_775107.1|ensembl:ENSG00000213186(gene)|ensembl:ENST00000309784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:+XLMj0dW09li5IMSmd2O00ETMCo2697049 rogid:H9mqvlmF70Qy0U+4e6WWQ49l9MI9606 rigid:S4HoKEmJ+UJcLTg5yXZ2D+iYJrs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-25475912 uniprotkb:Q9UJZ1 - intact:EBI-1044428|ensembl:ENSP00000348886|uniprotkb:O60376|uniprotkb:Q53G29|uniprotkb:Q96FY2|uniprotkb:Q9P042|uniprotkb:D3DRN3|uniprotkb:B4E1K7 psi-mi:orf3b_wcpv(display_short)|psi-mi:EBI-25475912(display_long) psi-mi:stml2_human(display_long)|uniprotkb:EPB72-like protein 2(gene name synonym)|uniprotkb:STOML2(gene name)|psi-mi:STOML2(display_short)|uniprotkb:SLP2(gene name synonym)|uniprotkb:HSPC108(orf name)|uniprotkb:Paraprotein target 7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375902|imex:IM-28441-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000165283(gene)|ensembl:ENST00000356493(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q9UJZ1|reactome:R-HSA-8949664|refseq:NP_001273960.1|refseq:NP_038470.1|refseq:NP_001273961.1 - - - figure legend:Table 2, no 23|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:LNnBgjGFy8zafnaLYrnmpl9SfoY2697049 rogid:VH6uT4ShPg3IpPHbQtaSVXjZAYg9606 rigid:nrsa1uOGhXGBfadMFcsYhrANqiE false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC6 uniprotkb:P52948 intact:EBI-25475897 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:ns6_sars2(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375942|imex:IM-28441-133 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:YP_009724394.1 refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4NdP8RUa3oCbTsAbQRdLakaDvDI2697049 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 rigid:+yOqd08s3aapNUHOF6kr8azrjwI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC6 uniprotkb:Q9NZJ7 intact:EBI-25475897 intact:EBI-297455|ensembl:ENSP00000362730|uniprotkb:Q6PK60|uniprotkb:Q6UX45|uniprotkb:Q7L465|uniprotkb:Q9BW23|uniprotkb:Q9NZR6|uniprotkb:Q9UJZ5|uniprotkb:B2RCE3|uniprotkb:A8KAX5 psi-mi:ns6_sars2(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:mtch1_human(display_long)|uniprotkb:Presenilin-associated protein(gene name synonym)|uniprotkb:CGI-64(orf name)|uniprotkb:MTCH1(gene name)|psi-mi:MTCH1(display_short)|uniprotkb:PSAP(gene name synonym)|uniprotkb:UNQ1871/PRO4314(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375942|imex:IM-28441-133 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:YP_009724394.1 ensembl:ENSG00000137409(gene)|ensembl:ENST00000373627(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045161"(neuronal ion channel clustering)|interpro:IPR018108|interpro:IPR023395|mint:Q9NZJ7|refseq:NP_055156.1|refseq:NP_001258570.1 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4NdP8RUa3oCbTsAbQRdLakaDvDI2697049 rogid:I0J5CxSiLB4OS6mhqwygLq389xY9606 rigid:+yOqd08s3aapNUHOF6kr8azrjwI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC6 uniprotkb:P78406 intact:EBI-25475897 intact:EBI-724495|uniprotkb:O15306|uniprotkb:Q3SYL7|uniprotkb:Q5TCH8|uniprotkb:Q6V708|uniprotkb:Q9H100|uniprotkb:Q9NQM6|ensembl:ENSP00000360286|ensembl:ENSP00000379181|ensembl:ENSP00000379182|uniprotkb:A8K882 psi-mi:ns6_sars2(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:rae1l_human(display_long)|uniprotkb:mRNA-associated protein mrnp 41(gene name synonym)|uniprotkb:Rae1 protein homolog(gene name synonym)|uniprotkb:RAE1(gene name)|psi-mi:RAE1(display_short)|uniprotkb:MRNP41(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375942|imex:IM-28441-133 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:YP_009724394.1 refseq:NP_001015885.1|refseq:NP_003601.1|ensembl:ENSG00000101146(gene)|ensembl:ENST00000371242(transcript)|ensembl:ENST00000395840(transcript)|ensembl:ENST00000395841(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037631|mint:P78406|rcsb pdb:3MMY|rcsb pdb:4OWR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|interpro:IPR019775|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|refseq:XP_011527390.1|refseq:XP_011527391.1|refseq:XP_005260639.2|dip:DIP-41063N - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4NdP8RUa3oCbTsAbQRdLakaDvDI2697049 rogid:JK4Y5p3WUcHFXBXyhhqCnDnG49c9606 rigid:+yOqd08s3aapNUHOF6kr8azrjwI false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC7 uniprotkb:Q9NU22 intact:EBI-25475903 intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895 psi-mi:ns7a_sars2(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375952|imex:IM-28441-117 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|rcsb pdb:7CI3|go:"GO:0016021"(integral component of membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044390|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|rcsb pdb:6W37|refseq:YP_009724395.1|reactome:R-HSA-9694322|reactome:R-HSA-9694614 refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol) - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:1KVY8uj2xaZWcmLYK01Bgv9bjPo2697049 rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606 rigid:MaZURyIlrzc/l41+LPvjiXtoAgs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC7 uniprotkb:Q7Z4Q2 intact:EBI-25475903 intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|uniprotkb:A8K1N4|ensembl:ENSP00000299192 psi-mi:ns7a_sars2(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375952|imex:IM-28441-117 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|rcsb pdb:7CI3|go:"GO:0016021"(integral component of membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044390|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|rcsb pdb:6W37|refseq:YP_009724395.1|reactome:R-HSA-9694322|reactome:R-HSA-9694614 refseq:NP_891552.1|ensembl:ENSG00000155393(gene)|ensembl:ENST00000299192(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR016024(Armadillo-type fold)|mint:Q7Z4Q2 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:1KVY8uj2xaZWcmLYK01Bgv9bjPo2697049 rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606 rigid:MaZURyIlrzc/l41+LPvjiXtoAgs false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q96IV0 intact:EBI-25475900 intact:EBI-6165879|ensembl:ENSP00000280700|uniprotkb:B4DJE9|uniprotkb:Q59FB1|uniprotkb:Q6PJD8|uniprotkb:Q9BVR8|uniprotkb:Q9NR70 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:ngly1_human(display_long)|uniprotkb:NGLY1(gene name)|psi-mi:NGLY1(display_short)|uniprotkb:N-glycanase 1(gene name synonym)|uniprotkb:PNG1(gene name synonym)|uniprotkb:"Peptide:N-glycanase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000151092(gene)|ensembl:ENST00000280700(transcript)|go:"GO:0000224"("peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR006588(Protein of unknown function PAW)|interpro:IPR008979(Galactose-binding like)|interpro:IPR018997|interpro:IPR036339|interpro:IPR038680|interpro:IPR038765|mint:Q96IV0|rcsb pdb:2CCQ|rcsb pdb:2CM0|reactome:R-HSA-532668|refseq:NP_001138767.1|refseq:NP_060767.2|refseq:NP_001138765.1|refseq:NP_001138766.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:CujOKLkvqxGmWpFvJM3B894PHqc9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q8N0Z8 intact:EBI-25475900 intact:EBI-7825279|ensembl:ENSP00000368318|uniprotkb:B4DP76|intact:MINT-8052350|uniprotkb:Q5TA41 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:pusl1_human(display_long)|uniprotkb:PUSL1(gene name)|psi-mi:PUSL1(display_short)|uniprotkb:tRNA pseudouridylate synthase-like 1(gene name synonym)|uniprotkb:tRNA-uridine isomerase-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000169972(gene)|ensembl:ENST00000379031(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|interpro:IPR020095|interpro:IPR020097|interpro:IPR020103|mint:Q8N0Z8|refseq:NP_699170.1 - - comment:mint figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:vj5uJUn7ENAZyPHxu981q6+X3W49606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q96AY3 intact:EBI-25475900 intact:EBI-2372475|uniprotkb:Q7Z3R4|uniprotkb:Q9H3N3|uniprotkb:Q9H6N5|uniprotkb:Q9UF89|uniprotkb:Q9H6J3|ensembl:ENSP00000317232 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:fkb10_human(display_long)|uniprotkb:FKBP10(gene name)|psi-mi:FKBP10(display_short)|uniprotkb:FKBP65(gene name synonym)|uniprotkb:FK506-binding protein 10(gene name synonym)|uniprotkb:Immunophilin FKBP65(gene name synonym)|uniprotkb:65 kDa FK506-binding protein(gene name synonym)|uniprotkb:PSEC0056(orf name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_068758.3|ensembl:ENSG00000141756(gene)|ensembl:ENST00000321562(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0018208"(peptidyl-proline modification)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042060"(wound healing)|go:"GO:0085029"(extracellular matrix assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q96AY3 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:+oJpWT3zBh/fq0DqKPapFoVt3u09606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q13443 intact:EBI-25475900 intact:EBI-77903|uniprotkb:B7ZLN7|ensembl:ENSP00000419446|uniprotkb:Q10718|uniprotkb:Q8NFM6 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:adam9_human(display_long)|uniprotkb:ADAM9(gene name)|psi-mi:ADAM9(display_short)|uniprotkb:KIAA0021(gene name synonym)|uniprotkb:MCMP(gene name synonym)|uniprotkb:MDC9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)|uniprotkb:Cellular disintegrin-related protein(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:MLTNG(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 go:"GO:0007160"(cell-matrix adhesion)|ensembl:ENSG00000168615(gene)|ensembl:ENST00000487273(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0097327"(response to antineoplastic agent)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|rcsb pdb:1M1V|reactome:R-HSA-1442490|refseq:NP_003807.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:cgdFZLtfiaqZ+oJvDARR1AbFA+I9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9Y680 intact:EBI-25475900 intact:EBI-3918971|uniprotkb:Q96DA4|uniprotkb:Q9Y6B0|uniprotkb:Q86U65|uniprotkb:Q6V3B2|uniprotkb:Q4ZG70|ensembl:ENSP00000413152 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:fkbp7_human(display_long)|uniprotkb:FKBP7(gene name)|psi-mi:FKBP7(display_short)|uniprotkb:FKBP23(gene name synonym)|uniprotkb:23 kDa FK506-binding protein(gene name synonym)|uniprotkb:FK506-binding protein 7(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:UNQ670/PRO1304(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001128684.1|refseq:NP_851939.1|ensembl:ENSG00000079150(gene)|ensembl:ENST00000424785(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0018208"(peptidyl-proline modification)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9Y680 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:HJ80Z7OSdidxr1a/p1IYSkVMGGY9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9Y4L1 intact:EBI-25475900 intact:EBI-1054186|uniprotkb:Q2I204|uniprotkb:Q53H25|uniprotkb:B7Z909|uniprotkb:A8C1Z0|ensembl:ENSP00000480150|ensembl:ENSP00000486825 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:hyou1_human(display_long)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)|uniprotkb:GRP170(gene name synonym)|uniprotkb:HYOU1(gene name)|psi-mi:HYOU1(display_short)|uniprotkb:ORP150(gene name synonym)|uniprotkb:170 kDa glucose-regulated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001124463.1|refseq:NP_006380.1|refseq:XP_016872585.1|refseq:XP_016872586.1|ensembl:ENSG00000149428(gene)|ensembl:ENSG00000280682(gene)|ensembl:ENST00000617285(transcript)|ensembl:ENST00000630669(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q9Y4L1|reactome:R-HSA-3000484|reactome:R-HSA-381038|go:"GO:0005790"(smooth endoplasmic reticulum) - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:xqSFRaiiHJLNVqgh87tHx9lfnS49606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9UHI8 intact:EBI-25475900 intact:EBI-2511802|ensembl:ENSP00000284984|uniprotkb:Q9NSJ8|uniprotkb:Q9UP80|uniprotkb:Q9UH83|uniprotkb:Q9P2K0|uniprotkb:D3DSD5 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:ats1_human(display_long)|uniprotkb:ADAMTS1(gene name)|psi-mi:ADAMTS1(display_short)|uniprotkb:KIAA1346(gene name synonym)|uniprotkb:METH1(gene name synonym)|uniprotkb:METH-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000154734(gene)|ensembl:ENST00000284984(transcript)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001822"(kidney development)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0060347"(heart trabecula formation)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR010294(ADAM-TS Spacer 1)|interpro:IPR013273(Peptidase M12B, ADAM-TS)|interpro:IPR013274(Peptidase M12B, ADAM-TS1)|interpro:IPR024079|interpro:IPR036383|interpro:IPR041645|rcsb pdb:2JIH|rcsb pdb:2V4B|rcsb pdb:3Q2G|rcsb pdb:3Q2H|reactome:R-HSA-1474228|reactome:R-HSA-5083635|reactome:R-HSA-5173214|refseq:NP_008919.3 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:/2rwfNnTU6Seo5+ZZdGeEEUeoAQ9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9P2E5 intact:EBI-25475900 intact:EBI-11733862|ensembl:ENSP00000035307|uniprotkb:B2DBD8|uniprotkb:Q6P2I4|uniprotkb:Q6UXD2 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:chpf2_human(display_long)|uniprotkb:CHPF2(gene name)|psi-mi:CHPF2(display_short)|uniprotkb:CHSY3(gene name synonym)|uniprotkb:CSGLCAT(gene name synonym)|uniprotkb:KIAA1402(gene name synonym)|uniprotkb:CSGlcA-T(gene name synonym)|uniprotkb:Chondroitin glucuronyltransferase(gene name synonym)|uniprotkb:Chondroitin polymerizing factor 2(gene name synonym)|uniprotkb:Chondroitin synthase 3(gene name synonym)|uniprotkb:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase(gene name synonym)|uniprotkb:UNQ299/PRO339(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000033100(gene)|ensembl:ENST00000035307(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0047238"(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0050510"(N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|reactome:R-HSA-2022870|refseq:NP_061888.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:8b6T33i9aZO/Af6lE6TxbbvuxBg9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9NYU1 intact:EBI-25475900 intact:EBI-1054215|uniprotkb:Q5JQR8|uniprotkb:Q9UFC4|uniprotkb:Q08AD0|uniprotkb:A6NKL4|uniprotkb:Q8N5K0|ensembl:ENSP00000365938 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:uggg2_human(display_long)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase 2"(gene name synonym)|uniprotkb:UGGT2(gene name)|psi-mi:UGGT2(display_short)|uniprotkb:UGT2(gene name synonym)|uniprotkb:UGCGL2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_064506.3|ensembl:ENSG00000102595(gene)|ensembl:ENST00000376747(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|reactome:R-HSA-901032 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:jEO6Ao5a4/iJg3Y1DeBydzHDYWM9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9NXK8 intact:EBI-25475900 intact:EBI-719790|uniprotkb:Q9H5K4|uniprotkb:B3KSJ8|ensembl:ENSP00000247977 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:fxl12_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 12(gene name synonym)|uniprotkb:F-box protein FBL12(gene name synonym)|uniprotkb:FBXL12(gene name)|psi-mi:FBXL12(display_short)|uniprotkb:FBL12(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_060173.1|refseq:NP_001303865.1|refseq:NP_001303866.1|refseq:NP_001303867.1|refseq:NP_001303868.1|refseq:NP_001303869.1|refseq:NP_001303870.1|refseq:NP_001303871.1|ensembl:ENSG00000127452(gene)|ensembl:ENST00000247977(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|mint:Q9NXK8|reactome:R-HSA-8951664|reactome:R-HSA-983168 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:b+3vZLMbZvEww+hdTa3YnLkPiC49606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9H8W4 intact:EBI-25475900 intact:EBI-742388|ensembl:ENSP00000322373|ensembl:ENSP00000427792 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:pkhf2_human(display_long)|uniprotkb:Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains(gene name synonym)|uniprotkb:PLEKHF2(gene name)|psi-mi:PLEKHF2(display_short)|uniprotkb:ZFYVE18(gene name synonym)|uniprotkb:PH and FYVE domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 18(gene name synonym)|uniprotkb:Phafin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 mint:Q9H8W4|ensembl:ENSG00000175895(gene)|ensembl:ENST00000315367(transcript)|ensembl:ENST00000519516(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037871|refseq:NP_078889.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:frYANUSmDIntPcZwWDW4YCQuMEw9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9H4F8 intact:EBI-25475900 intact:EBI-2801103|uniprotkb:B2R7P5|uniprotkb:Q96F78|uniprotkb:A8K1S3|ensembl:ENSP00000370680 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:smoc1_human(display_long)|uniprotkb:Secreted modular calcium-binding protein 1(gene name synonym)|uniprotkb:SMOC1(gene name)|psi-mi:SMOC1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001030024.1|refseq:NP_071420.1|ensembl:ENSG00000198732(gene)|ensembl:ENST00000381280(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0008201"(heparin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060173"(limb development)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR019577|interpro:IPR036058|interpro:IPR036857|interpro:IPR037639 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:EA0b+kWuv4b9e19gotvuaTm3GE09606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9H488 intact:EBI-25475900 intact:EBI-2564472|uniprotkb:A8K4R8|uniprotkb:Q14685|uniprotkb:Q5W185|uniprotkb:Q9BW76|uniprotkb:E1P5M4|ensembl:ENSP00000364902 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:ofut1_human(display_long)|uniprotkb:POFUT1(gene name)|psi-mi:POFUT1(display_short)|uniprotkb:FUT12(gene name synonym)|uniprotkb:KIAA0180(gene name synonym)|uniprotkb:Peptide-O-fucosyltransferase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_056167.1|refseq:NP_758436.1|ensembl:ENSG00000101346(gene)|ensembl:ENST00000375749(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006004"(fucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008417"(fucosyltransferase activity)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016266"(O-glycan processing)|go:"GO:0036066"(protein O-linked fucosylation)|go:"GO:0046922"(peptide-O-fucosyltransferase activity)|interpro:IPR019378|interpro:IPR039922|rcsb pdb:5UX6|rcsb pdb:5UXH|reactome:R-HSA-1912399 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:XqxIDXSKUkpXsbJSx0sN8tkbV3E9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9H173 intact:EBI-25475900 intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9BZQ6 intact:EBI-25475900 intact:EBI-2556756|uniprotkb:B7ZLZ2|uniprotkb:Q9UFV7|uniprotkb:Q0VGM5|uniprotkb:B2RCH6|uniprotkb:Q9HCW1|uniprotkb:Q5TEZ0|uniprotkb:Q7L2Y5|ensembl:ENSP00000318147|intact:EBI-11137062 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:edem3_human(display_long)|uniprotkb:C1orf22(gene name synonym)|uniprotkb:EDEM3(gene name)|psi-mi:EDEM3(display_short)|uniprotkb:Alpha-1,2-mannosidase EDEM3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_079467.3|ensembl:ENSG00000116406(gene)|ensembl:ENST00000318130(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR003137(Protease-associated PA)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR037322|interpro:IPR044674|reactome:R-HSA-901032|refseq:NP_001306889.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:Y+n8Hhal53ri5I8jlKzXI6S8pk09606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9BS26 intact:EBI-25475900 intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000023318(gene)|ensembl:ENST00000262455(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009986"(cell surface)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|go:"GO:0009100"(glycoprotein metabolic process)|refseq:NP_055866.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:TpwaFRifveb03iRPS2pEZve1kLA9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q9BRN9 intact:EBI-25475900 intact:EBI-21503420|uniprotkb:B2RDK9|uniprotkb:Q9H046|uniprotkb:Q9H651|ensembl:ENSP00000330433 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:tm2d3_human(display_long)|uniprotkb:Beta-amyloid-binding protein-like protein 2(gene name synonym)|uniprotkb:TM2D3(gene name)|psi-mi:TM2D3(display_short)|uniprotkb:BLP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_079417.2|refseq:NP_510883.2|go:"GO:0046331"(lateral inhibition)|interpro:IPR007829(TM2)|ensembl:ENSG00000184277(gene)|ensembl:ENST00000333202(transcript)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045747"(positive regulation of Notch signaling pathway) - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:NoubejSjL7hXF6697EGHxxJ7t+A9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q99988 intact:EBI-25475900 intact:EBI-2116863|uniprotkb:O14629|uniprotkb:P78360|uniprotkb:Q9NRT0|uniprotkb:Q9BWA0|ensembl:ENSP00000252809 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:gdf15_human(display_long)|uniprotkb:GDF15(gene name)|psi-mi:GDF15(display_short)|uniprotkb:MIC1(gene name synonym)|uniprotkb:PDF(gene name synonym)|uniprotkb:PLAB(gene name synonym)|uniprotkb:PTGFB(gene name synonym)|uniprotkb:Placental bone morphogenetic protein(gene name synonym)|uniprotkb:Placental TGF-beta(gene name synonym)|uniprotkb:Macrophage inhibitory cytokine 1(gene name synonym)|uniprotkb:Prostate differentiation factor(gene name synonym)|uniprotkb:NSAID-activated gene 1 protein(gene name synonym)|uniprotkb:NSAID-regulated gene 1 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_004855.2|ensembl:ENSG00000130513(gene)|ensembl:ENST00000252809(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002023"(reduction of food intake in response to dietary excess)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008083"(growth factor activity)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035860"(glial cell-derived neurotrophic factor receptor signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0060400"(negative regulation of growth hormone receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070700"(BMP receptor binding)|go:"GO:1901741"(positive regulation of myoblast fusion)|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR029034|rcsb pdb:5VT2|rcsb pdb:5VZ3|rcsb pdb:5VZ4|rcsb pdb:6Q2J - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:W0oAT+oBcB2pzGNCol0EAfF7CqA9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q99519 intact:EBI-25475900 intact:EBI-721517|ensembl:ENSP00000229725|ensembl:ENSP00000364782|ensembl:ENSP00000399309|ensembl:ENSP00000401067|ensembl:ENSP00000403720|ensembl:ENSP00000408207|ensembl:ENSP00000408957|ensembl:ENSP00000409489 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:neur1_human(display_long)|uniprotkb:Lysosomal sialidase(gene name synonym)|uniprotkb:N-acetyl-alpha-neuraminidase 1(gene name synonym)|uniprotkb:Acetylneuraminyl hydrolase(gene name synonym)|uniprotkb:G9 sialidase(gene name synonym)|uniprotkb:NEU1(gene name)|psi-mi:NEU1(display_short)|uniprotkb:NANH(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_000425.1|ensembl:ENSG00000234343(gene)|ensembl:ENSG00000234846(gene)|ensembl:ENSG00000184494(gene)|ensembl:ENSG00000204386(gene)|ensembl:ENSG00000223957(gene)|ensembl:ENSG00000227129(gene)|ensembl:ENSG00000227315(gene)|ensembl:ENSG00000228691(gene)|ensembl:ENST00000229725(transcript)|ensembl:ENST00000375631(transcript)|ensembl:ENST00000411774(transcript)|ensembl:ENST00000422978(transcript)|ensembl:ENST00000423382(transcript)|ensembl:ENST00000434496(transcript)|ensembl:ENST00000437432(transcript)|ensembl:ENST00000439648(transcript)|go:"GO:0004308"(exo-alpha-sialidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006689"(ganglioside catabolic process)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016997"(alpha-sialidase activity)|go:"GO:0030054"(cell junction)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0052794"("exo-alpha-(2->3)-sialidase activity")|go:"GO:0052795"("exo-alpha-(2->6)-sialidase activity")|go:"GO:0052796"("exo-alpha-(2->8)-sialidase activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR011040(Neuraminidase)|interpro:IPR026856|interpro:IPR036278|mint:Q99519|reactome:R-HSA-1660662|reactome:R-HSA-4085001|reactome:R-HSA-4341670|reactome:R-HSA-6798695 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:ZVyKW74LB/iEd+Ys7Lm7ZyLvv609606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q99470 intact:EBI-25475900 intact:EBI-2515769|ensembl:ENSP00000247020|uniprotkb:Q9BQ79 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:sdf2_human(display_long)|uniprotkb:SDF2(gene name)|psi-mi:SDF2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000132581(gene)|ensembl:ENST00000247020(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR016093(MIR motif)|interpro:IPR036300|refseq:NP_008854.2 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:j0jeyDbvcmC8s+1awSiR7K/hyxo9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q96MM7 intact:EBI-25475900 intact:EBI-10981456|uniprotkb:Q6PIC4|uniprotkb:Q4VC07|uniprotkb:Q86SM9|uniprotkb:B9WRT5|uniprotkb:B9WRT4|uniprotkb:Q96SJ4|uniprotkb:Q8N3T4|uniprotkb:Q2TB13|uniprotkb:Q8NBN4|uniprotkb:E9PDY5|ensembl:ENSP00000359873|ensembl:ENSP00000384013 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:h6st2_human(display_long)|uniprotkb:HS6ST2(gene name)|psi-mi:HS6ST2(display_short)|uniprotkb:PSEC0092(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001070656.1|refseq:NP_671704.3|refseq:XP_005262547.1|refseq:XP_011529708.1|refseq:XP_016885433.1|refseq:XP_016885434.1|ensembl:ENSG00000171004(gene)|ensembl:ENST00000370836(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0015015"(heparan sulfate proteoglycan biosynthetic process, enzymatic modification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017095"(heparan sulfate 6-O-sulfotransferase activity)|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|interpro:IPR010635(Heparan sulphate 6-sulphotransferase)|interpro:IPR027417|reactome:R-HSA-2022928|ensembl:ENST00000406696(transcript) - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:RT5E9eyaRk49nCvVuisl/6Sje6A9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q96F46 intact:EBI-25475900 intact:EBI-5591258|uniprotkb:O43844|uniprotkb:Q20WK1|ensembl:ENSP00000320936 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:i17ra_human(display_long)|uniprotkb:IL17RA(gene name)|psi-mi:IL17RA(display_short)|uniprotkb:IL17R(gene name synonym)|uniprotkb:CDw217(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_055154.3|refseq:NP_001276834.1|reactome:R-HSA-448424|ensembl:ENSG00000177663(gene)|ensembl:ENST00000319363(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009615"(response to virus)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0072537"(fibroblast activation)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR013568(SEFIR)|interpro:IPR032356|interpro:IPR038683|interpro:IPR039465|interpro:IPR043046|rcsb pdb:3JVF|rcsb pdb:4HSA|rcsb pdb:4NUX|rcsb pdb:5N9B|rcsb pdb:5NAN - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:5qXoQilp6J+JgOi5gpj8i0QTgCk9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q96DZ1 intact:EBI-25475900 intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q92820 intact:EBI-25475900 intact:EBI-3045534|ensembl:ENSP00000260118 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q8N766 intact:EBI-25475900 intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q8IZ52 intact:EBI-25475900 intact:EBI-372500|uniprotkb:Q6UXD6|uniprotkb:Q7L4G1|uniprotkb:Q9H0F8|uniprotkb:Q9H618|ensembl:ENSP00000243776|uniprotkb:B4DXU0 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:chss2_human(display_long)|uniprotkb:UNQ651/PRO1281(orf name)|uniprotkb:Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II(gene name synonym)|uniprotkb:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II(gene name synonym)|uniprotkb:Chondroitin glucuronyltransferase 2(gene name synonym)|uniprotkb:N-acetylgalactosaminyltransferase 2(gene name synonym)|uniprotkb:Chondroitin-polymerizing factor(gene name synonym)|uniprotkb:CHPF(gene name)|psi-mi:CHPF(display_short)|uniprotkb:CSS2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001182660.1|refseq:NP_078812.2|ensembl:ENSG00000123989(gene)|ensembl:ENST00000243776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047238"(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0050510"(N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|reactome:R-HSA-2022870|go:"GO:0016021"(integral component of membrane) - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:jfN5U87odagTLP2MJVqowoS6TBw9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q8IWF2 intact:EBI-25475900 intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q8IV08 intact:EBI-25475900 intact:EBI-2689908|uniprotkb:Q9BW87|uniprotkb:Q92853|ensembl:ENSP00000348901|ensembl:ENSP00000386293|ensembl:ENSP00000386938|ensembl:ENSP00000387022|ensembl:ENSP00000387050 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:pld3_human(display_long)|uniprotkb:Choline phosphatase 3(gene name synonym)|uniprotkb:HindIII K4L homolog(gene name synonym)|uniprotkb:Hu-K4(gene name synonym)|uniprotkb:Phosphatidylcholine-hydrolyzing phospholipase D3(gene name synonym)|uniprotkb:Phospholipase D3(gene name synonym)|uniprotkb:PLD3(gene name)|psi-mi:PLD3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001278240.1|refseq:XP_011524994.1|refseq:XP_011524995.1|refseq:NP_001026866.1|refseq:NP_036400.2|refseq:XP_005258761.1|refseq:XP_005258764.1|refseq:XP_005258765.1|refseq:XP_005258766.1|refseq:XP_005258767.1|ensembl:ENSG00000105223(gene)|ensembl:ENST00000356508(transcript)|ensembl:ENST00000409281(transcript)|ensembl:ENST00000409419(transcript)|ensembl:ENST00000409587(transcript)|ensembl:ENST00000409735(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002376"(immune system process)|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|interpro:IPR001736(Phospholipase D/Transphosphatidylase)|interpro:IPR032803|reactome:R-HSA-1483148|reactome:R-HSA-2029485|refseq:XP_006723185.1|refseq:XP_016882035.1|refseq:XP_016882036.1|refseq:XP_016882037.1|refseq:XP_016882038.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:UAnUtENnwfOxhcqSzMmb7yOlBFI9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q86YB8 intact:EBI-25475900 intact:EBI-2806988|uniprotkb:Q5T1H4|uniprotkb:Q9NR62|uniprotkb:Q8IZ11|ensembl:ENSP00000346635|uniprotkb:B4DF57 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:ero1b_human(display_long)|uniprotkb:ERO1B(gene name)|psi-mi:ERO1B(display_short)|uniprotkb:ERO1LB(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductase beta(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductin-1-like protein B(gene name synonym)|uniprotkb:Oxidoreductin-1-L-beta(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_063944.3|ensembl:ENSG00000086619(gene)|ensembl:ENST00000354619(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071949"(FAD binding)|interpro:IPR007266(Endoplasmic reticulum oxidoreductin 1)|interpro:IPR037192|reactome:R-HSA-264876 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:1VWEikdUOB9LvVu9PegpX72OYd49606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q7Z4H8 intact:EBI-25475900 intact:EBI-2865988|uniprotkb:Q8NE24|uniprotkb:Q8N7L8|uniprotkb:Q6UWW2|uniprotkb:Q6ZUM9|ensembl:ENSP00000315386 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:plgt3_human(display_long)|uniprotkb:POGLUT3(gene name)|psi-mi:POGLUT3(display_short)|uniprotkb:KDEL motif-containing protein 2(gene name synonym)|uniprotkb:KDELC2(gene name synonym)|uniprotkb:Protein O-xylosyltransferase POGLUT3(gene name synonym)|uniprotkb:UNQ1904/PRO4350(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_714916.3|ensembl:ENSG00000178202(gene)|ensembl:ENST00000323468(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0012505"(endomembrane system)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0035251"(UDP-glucosyltransferase activity)|go:"GO:0035252"(UDP-xylosyltransferase activity)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0140561"(EGF-domain serine glucosyltransferase activity)|go:"GO:0140562"(EGF-domain serine xylosyltransferase activity)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR006598(Lipopolysaccharide-modifying protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:utLTYC5qTbxTTVDlH7SQCOZUrH09606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q6UW63 intact:EBI-25475900 intact:EBI-11079743|uniprotkb:Q9BVD2|uniprotkb:Q53HL3|ensembl:ENSP00000365172 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:plgt2_human(display_long)|uniprotkb:POGLUT2(gene name)|psi-mi:POGLUT2(display_short)|uniprotkb:Endoplasmic reticulum resident protein 58(gene name synonym)|uniprotkb:KDEL motif-containing protein 1(gene name synonym)|uniprotkb:KDELC1(gene name synonym)|uniprotkb:Protein O-xylosyltransferase POGLUT2(gene name synonym)|uniprotkb:UNQ1910/PRO4357(orf name)|uniprotkb:EP58(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_076994.2|refseq:NP_001305661.1|ensembl:ENSG00000134901(gene)|ensembl:ENST00000376004(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0012505"(endomembrane system)|go:"GO:0018242"(protein O-linked glycosylation via serine)|go:"GO:0035251"(UDP-glucosyltransferase activity)|go:"GO:0035252"(UDP-xylosyltransferase activity)|go:"GO:0046527"(glucosyltransferase activity)|go:"GO:0140561"(EGF-domain serine glucosyltransferase activity)|go:"GO:0140562"(EGF-domain serine xylosyltransferase activity)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR006598(Lipopolysaccharide-modifying protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|rcsb pdb:2DI7 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:L/z8XMVlmk8LgPztoc5ZFKUooLE9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q15818 intact:EBI-25475900 intact:EBI-11042445|uniprotkb:Q5FWE6|uniprotkb:B3KXH3|ensembl:ENSP00000307549 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:nptx1_human(display_long)|uniprotkb:NPTX1(gene name)|psi-mi:NPTX1(display_short)|uniprotkb:Neuronal pentraxin I(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_002513.2|ensembl:ENSG00000171246(gene)|ensembl:ENST00000306773(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007417"(central nervous system development)|go:"GO:0030133"(transport vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0060385"(axonogenesis involved in innervation)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:Q15818|rcsb pdb:6YPE - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:RmnlnDZftUYo1Qxhhw1bfl0Gf289606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q13438 intact:EBI-25475900 intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:Q08431 intact:EBI-25475900 intact:EBI-3449497|uniprotkb:Q53FU9|uniprotkb:Q9BTL9|uniprotkb:B2R6M7|uniprotkb:Q7Z3D2|uniprotkb:F5GZN3|ensembl:ENSP00000268150|ensembl:ENSP00000456281 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:mfgm_human(display_long)|uniprotkb:MFGE8(gene name)|psi-mi:MFGE8(display_short)|uniprotkb:Breast epithelial antigen BA46(gene name synonym)|uniprotkb:HMFG(gene name synonym)|uniprotkb:MFGM(gene name synonym)|uniprotkb:Milk fat globule-EGF factor 8(gene name synonym)|uniprotkb:SED1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_005919.2|refseq:NP_001108086.1|refseq:NP_001297248.1|refseq:NP_001297249.1|refseq:NP_001297250.1|ensembl:ENSG00000140545(gene)|ensembl:ENST00000268150(transcript)|ensembl:ENST00000566497(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007338"(single fertilization)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977225 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:rj2XTJMMYB6NPDRjQX9LSEuF3Qw9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P61916 intact:EBI-25475900 intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P58166 intact:EBI-25475900 intact:EBI-21580393|ensembl:ENSP00000266646 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:inhbe_human(display_long)|uniprotkb:Activin beta-E chain(gene name synonym)|uniprotkb:INHBE(gene name)|psi-mi:INHBE(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_113667.1|ensembl:ENSG00000139269(gene)|ensembl:ENST00000266646(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001318(Inhibin, beta C subunit)|interpro:IPR001839(Transforming growth factor beta)|interpro:IPR015615(Transforming growth factor-beta-related)|interpro:IPR017948|interpro:IPR029034|reactome:R-HSA-209822 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:lpcexcaklLf/tvehM6ZztIFyVh09606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P29122 intact:EBI-25475900 intact:EBI-2683528|uniprotkb:Q9UEJ8|uniprotkb:Q9UEJ9|uniprotkb:Q15100|uniprotkb:Q9Y4H1|uniprotkb:Q9UEJ1|uniprotkb:Q9Y4H0|uniprotkb:Q9UEJ2|uniprotkb:Q15099|uniprotkb:Q9UEJ7|uniprotkb:Q9Y4G9|uniprotkb:Q9UEG7|ensembl:ENSP00000482760 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:pcsk6_human(display_long)|uniprotkb:PACE4(gene name synonym)|uniprotkb:Paired basic amino acid cleaving enzyme 4(gene name synonym)|uniprotkb:Subtilisin-like proprotein convertase 4(gene name synonym)|uniprotkb:Subtilisin/kexin-like protease PACE4(gene name synonym)|uniprotkb:PCSK6(gene name)|psi-mi:PCSK6(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_002561.1|refseq:NP_612192.1|refseq:NP_612195.1|refseq:NP_612196.1|refseq:NP_612197.1|refseq:NP_001278238.1|refseq:NP_612198.2|ensembl:ENSG00000140479(gene)|ensembl:ENST00000611716(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008201"(heparin binding)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0032902"(nerve growth factor production)|go:"GO:0032940"(secretion by cell)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0051004"(regulation of lipoprotein lipase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010909(PLAC)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032778|interpro:IPR032815|interpro:IPR034182|interpro:IPR038466|reactome:R-HSA-1181150|reactome:R-HSA-167060|reactome:R-HSA-6809371|reactome:R-HSA-8963889|interpro:IPR036852|dip:DIP-29903N - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:Xh7YAAyyc+G8pX8aiioRKS4PB/Y9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P28300 intact:EBI-25475900 intact:EBI-3893481|uniprotkb:B2R5Q3|uniprotkb:Q5FWF0|ensembl:ENSP00000231004 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:lyox_human(display_long)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)|uniprotkb:Lysyl oxidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_002308.2|dip:DIP-49007N|ensembl:ENSG00000113083(gene)|ensembl:ENST00000231004(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0035905"(ascending aorta development)|go:"GO:0035906"(descending aorta development)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0055001"(muscle cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061448"(connective tissue development)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1900120"(regulation of receptor binding)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000586"(regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR019828|mint:P28300|reactome:R-HSA-1566948|reactome:R-HSA-2243919|go:"GO:0046716"(muscle cell cellular homeostasis) - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:bDUlKQ5akDOhya4GydJ+PaLs7Fo9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P26358 intact:EBI-25475900 intact:EBI-719459|uniprotkb:Q9UHG5|uniprotkb:Q9ULA2|uniprotkb:Q9UMZ6|uniprotkb:A0AV63|intact:EBI-28971395|ensembl:ENSP00000345739|uniprotkb:B7ZLW6 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:dnmt1_human(display_long)|uniprotkb:CXXC9(gene name synonym)|uniprotkb:MCMT(gene name synonym)|uniprotkb:DNA methyltransferase HsaI(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 9(gene name synonym)|uniprotkb:DNMT1(gene name)|psi-mi:DNMT1(display_short)|uniprotkb:AIM(gene name synonym)|uniprotkb:DNMT(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSP00000345739|ensembl:ENST00000359526|ensembl:ENSP00000352516|refseq:NP_001124295.1|refseq:NP_001370.1|ensembl:ENSG00000130816(gene)|ensembl:ENST00000340748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003886"("DNA (cytosine-5-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|reactome:R-HSA-427413|reactome:R-HSA-4655427|reactome:R-HSA-5334118|reactome:R-HSA-9710421|refseq:NP_001305659.1|refseq:NP_001305660.1|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905931"(negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001525(C-5 cytosine-specific DNA methylase)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR010506(DMAP1-binding)|interpro:IPR017198("DNA (cytosine-5)-methyltransferase 1")|interpro:IPR018117|interpro:IPR022702|interpro:IPR029063|interpro:IPR031303|interpro:IPR043151|mint:P26358|rcsb pdb:3EPZ|rcsb pdb:3PTA|rcsb pdb:3SWR|rcsb pdb:4WXX|rcsb pdb:4YOC|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5WVO|rcsb pdb:5YDR|rcsb pdb:6K3A|reactome:R-HSA-212300|dip:DIP-39693N - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:qae3zQwGP5R/+WCWoeahDKZ/9Jg9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P15151 intact:EBI-25475900 intact:EBI-3919694|uniprotkb:Q96BJ1|uniprotkb:Q15268|uniprotkb:Q15267|uniprotkb:P15152|uniprotkb:B4DTS9 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:pvr_human(display_long)|uniprotkb:PVR(gene name)|psi-mi:PVR(display_short)|uniprotkb:PVS(gene name synonym)|uniprotkb:Nectin-like protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 go:"GO:0001618"(virus receptor activity)|mint:P15151|refseq:NP_001129240.1|refseq:NP_001129241.1|refseq:NP_006496.4|refseq:NP_001129242.2|dip:DIP-43987N|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1DGI|rcsb pdb:1NN8|rcsb pdb:3EPC|rcsb pdb:3EPD|rcsb pdb:3EPF|rcsb pdb:3J8F|rcsb pdb:3J9F|rcsb pdb:3UDW|rcsb pdb:3URO|rcsb pdb:4FQP|rcsb pdb:6ARQ|rcsb pdb:6ISC|rcsb pdb:6O3O|reactome:R-HSA-198933|reactome:R-HSA-420597 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:PsTFmeD+9vG6ieNef6MupXts60g9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P12109 intact:EBI-25475900 intact:EBI-2465913|ensembl:ENSP00000355180|uniprotkb:O00117|uniprotkb:O00118|uniprotkb:Q14040|uniprotkb:Q14041|uniprotkb:Q16258|uniprotkb:Q7Z645|uniprotkb:Q9BSA8 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:co6a1_human(display_long)|uniprotkb:COL6A1(gene name)|psi-mi:COL6A1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000142156(gene)|ensembl:ENST00000361866(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005518"(collagen binding)|go:"GO:0005589"(collagen type VI trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042383"(sarcolemma)|go:"GO:0005576"(extracellular region)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8948216|refseq:NP_001839.2 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:ziEV+a4Xb+C4ioMe8uoISJitR6E9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P0C7P0 intact:EBI-25475900 intact:EBI-11150788|ensembl:ENSP00000483781|ensembl:ENSP00000484950 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:cisd3_human(display_long)|uniprotkb:CISD3(gene name)|psi-mi:CISD3(display_short)|uniprotkb:Mitochondrial inner NEET protein(gene name synonym)|uniprotkb:MitoNEET-related protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001129970.1|ensembl:ENSG00000274768(gene)|ensembl:ENSG00000277972(gene)|ensembl:ENST00000613478(transcript)|ensembl:ENST00000620783(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|interpro:IPR018967|interpro:IPR042216|rcsb pdb:6AVJ - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:D0xBgqlDr4XQZSsoYvZ0ARGMU6M9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P05556 intact:EBI-25475900 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:P00750 intact:EBI-25475900 intact:EBI-5605520|uniprotkb:A8K022|uniprotkb:B2R8E8|uniprotkb:Q15103|uniprotkb:Q503B0|uniprotkb:Q6PJA5|uniprotkb:Q7Z7N2|uniprotkb:Q86YK8|uniprotkb:Q9BU99|uniprotkb:Q9BZW1|ensembl:ENSP00000220809|ensembl:ENSP00000392045|ensembl:ENSP00000504311 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:tpa_human(display_long)|uniprotkb:PLAT(gene name)|psi-mi:PLAT(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_001306118.1|refseq:NP_000921.1|refseq:NP_127509.1|ensembl:ENSG00000104368(gene)|ensembl:ENST00000220809(transcript)|ensembl:ENST00000429089(transcript)|ensembl:ENST00000679151(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0030141"(secretory granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045177"(apical part of cell)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060468"(prevention of polyspermy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099183"(trans-synaptic signaling by BDNF, modulating synaptic transmission)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR026280|interpro:IPR033116|interpro:IPR034811|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1A5H|rcsb pdb:1BDA|rcsb pdb:1PK2|rcsb pdb:1PML|rcsb pdb:1RTF|rcsb pdb:1TPG|rcsb pdb:1TPK|rcsb pdb:1TPM|rcsb pdb:1TPN|rcsb pdb:5BRR|rcsb pdb:5ZLZ|reactome:R-HSA-186797|reactome:R-HSA-75205 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:YG0q3fS8FWhr/g9xuRyMM+oYcXo9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:O00469 intact:EBI-25475900 intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|uniprotkb:B3KWS3|ensembl:ENSP00000353170 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_000926.2|refseq:NP_891988.1|ensembl:ENSG00000152952(gene)|ensembl:ENST00000360060(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O00469|reactome:R-HSA-1650814 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:O76061 intact:EBI-25475900 intact:EBI-713858|ensembl:ENSP00000265087 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:stc2_human(display_long)|uniprotkb:Stanniocalcin-related protein(gene name synonym)|uniprotkb:STC2(gene name)|psi-mi:STC2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000113739(gene)|ensembl:ENST00000265087(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007566"(embryo implantation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0033280"(response to vitamin D)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0046697"(decidualization)|go:"GO:0046885"(regulation of hormone biosynthetic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR004978(Stanniocalcin)|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_003705.1 - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:qeBQhJwK594qy2xTfnfEwbeguuw9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTC8 uniprotkb:O14656 intact:EBI-25475900 intact:EBI-524257|uniprotkb:Q53Y64|uniprotkb:Q96CA0|uniprotkb:B2RB58|ensembl:ENSP00000345719 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:tor1a_human(display_long)|uniprotkb:Torsin family 1 member A(gene name synonym)|uniprotkb:Dystonia 1 protein(gene name synonym)|uniprotkb:TOR1A(gene name)|psi-mi:TOR1A(display_short)|uniprotkb:DQ2(gene name synonym)|uniprotkb:DYT1(gene name synonym)|uniprotkb:TA(gene name synonym)|uniprotkb:Torsin ATPase-1A(gene name synonym)|uniprotkb:TORA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26375962|imex:IM-28441-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 ensembl:ENSG00000136827(gene)|ensembl:ENST00000351698(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006996"(organelle organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030426"(growth cone)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051584"(regulation of dopamine uptake involved in synaptic transmission)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061992"(obsolete ATP-dependent chaperone mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR010448(Torsin)|interpro:IPR017378(Torsin, subgroup)|interpro:IPR027417|interpro:IPR030549|rcsb pdb:5J1S|rcsb pdb:5J1T|rcsb pdb:6OIF|reactome:R-HSA-8856825|go:"GO:0031175"(neuron projection development)|refseq:NP_000104.1|dip:DIP-34411N - - - figure legend:Table 2, no 26|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:PeqPtp4z9AnOwDH1GXYATMaihkM9606 rigid:Vxz1rgLxGSfjZGUrOkMtv94/sx0 false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:Q9UL15 intact:EBI-25475909 intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:Q9UKA9 intact:EBI-25475909 intact:EBI-954220|ensembl:ENSP00000502818|uniprotkb:Q8N0Z1|uniprotkb:Q8N160|uniprotkb:Q8NFB0|uniprotkb:Q8NFB1|uniprotkb:Q969N9|uniprotkb:Q96Q76 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:ptbp2_human(display_long)|uniprotkb:Neurally-enriched homolog of PTB(gene name synonym)|uniprotkb:Neural polypyrimidine tract-binding protein(gene name synonym)|uniprotkb:PTB-like protein(gene name synonym)|uniprotkb:PTBP2(gene name)|psi-mi:PTBP2(display_short)|uniprotkb:NPTB(gene name synonym)|uniprotkb:PTB(gene name synonym)|uniprotkb:PTBLP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 rcsb pdb:2MJU|rcsb pdb:4CQ1|ensembl:ENSG00000117569(gene)|ensembl:ENST00000674951(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR034799|interpro:IPR034800|interpro:IPR035002|interpro:IPR035979|mint:Q9UKA9|rcsb pdb:2CQ1|refseq:NP_067013.1|refseq:NP_001287914.1|refseq:NP_001287915.1|refseq:NP_001287916.1|refseq:NP_001287917.1|refseq:NP_001287918.1|refseq:NP_001287919.1 - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:HRWj6xZbfhYShcsdMR97O7CD4/Y9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:Q9P0L2 intact:EBI-25475909 intact:EBI-968587|uniprotkb:Q2HIY1|uniprotkb:Q5VTF9|uniprotkb:Q5VTG0|uniprotkb:Q96SW9|uniprotkb:Q9P251|uniprotkb:D3DTB0|uniprotkb:D3DTB1|ensembl:ENSP00000355884 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:mark1_human(display_long)|uniprotkb:MARK1(gene name)|psi-mi:MARK1(display_short)|uniprotkb:KIAA1477(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:MAP/microtubule affinity-regulating kinase 1(gene name synonym)|uniprotkb:PAR1 homolog c(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_001273057.1|refseq:NP_061120.3|ensembl:ENSP00000355884|ensembl:ENST00000366918|ensembl:ENSP00000355885|dip:DIP-39777N|ensembl:ENSG00000116141(gene)|ensembl:ENST00000366917(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033627|mint:Q9P0L2|rcsb pdb:2HAK|rcsb pdb:3OSE|rcsb pdb:6C9D - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:/ydFAiGjuUcmwDHO4tEPSSMlVjY9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:Q9H773 intact:EBI-25475909 intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene) - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:4EfV2ZU2MgDiFXShthfualZnat09606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:Q9H2P9 intact:EBI-25475909 intact:EBI-21351611|ensembl:ENSP00000359127|ensembl:ENSP00000418282|uniprotkb:A8JZY6|uniprotkb:D3DT62|uniprotkb:Q9P017|uniprotkb:Q9P0I4|uniprotkb:Q9Y319 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:dph5_human(display_long)|uniprotkb:DPH5(gene name)|psi-mi:DPH5(display_short)|uniprotkb:Diphthamide biosynthesis methyltransferase(gene name synonym)|uniprotkb:AD-018(orf name)|uniprotkb:CGI-30(orf name)|uniprotkb:HSPC143(orf name)|uniprotkb:NPD015(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 ensembl:ENSG00000117543(gene)|ensembl:ENST00000370109(transcript)|ensembl:ENST00000488176(transcript)|go:"GO:0004164"(diphthine synthase activity)|go:"GO:0005829"(cytosol)|go:"GO:0017183"(peptidyl-diphthamide biosynthetic process from peptidyl-histidine)|go:"GO:0032259"(methylation)|interpro:IPR000878(Tetrapyrrole methylase)|interpro:IPR004551(Diphthine synthase)|interpro:IPR014776(Tetrapyrrole methylase, subdomain 2)|interpro:IPR014777(Tetrapyrrole methylase, subdomain 1)|interpro:IPR035996|reactome:R-HSA-5358493|refseq:NP_001070862.1|refseq:NP_001070863.1|refseq:NP_057042.2|refseq:XP_016856949.1 - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:jlFbyOzDPj70TTCRy3MDyl3WzAY9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:Q7KZI7 intact:EBI-25475909 intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|dip:DIP-31321N|ensembl:ENSG00000072518(gene)|ensembl:ENST00000402010(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001764"(neuron migration)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8 - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:P27448 intact:EBI-25475909 intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413(gene)|ensembl:ENST00000429436(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033628|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7O94|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:O94826 intact:EBI-25475909 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:O75534 intact:EBI-25475909 intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|ensembl:ENSP00000351329|ensembl:ENSP00000432958|uniprotkb:A8K281|uniprotkb:G5E9Q2 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307(gene)|ensembl:ENST00000358528(transcript)|ensembl:ENST00000534699(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008584"(male gonad development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|interpro:IPR012340(Nucleic acid-binding, OB-fold) - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:O43633 intact:EBI-25475909 intact:EBI-2692789|uniprotkb:B2R4W6|uniprotkb:Q3ZTT0|ensembl:ENSP00000310440|ensembl:ENSP00000469240|ensembl:ENSP00000472680 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:chm2a_human(display_long)|uniprotkb:BC2(gene name synonym)|uniprotkb:CHMP2(gene name synonym)|uniprotkb:Chromatin-modifying protein 2a(gene name synonym)|uniprotkb:Putative breast adenocarcinoma marker BC-2(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 2-1(gene name synonym)|uniprotkb:CHMP2A(gene name)|psi-mi:CHMP2A(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_055268.1|refseq:NP_940818.1|ensembl:ENSG00000130724(gene)|ensembl:ENST00000312547(transcript)|ensembl:ENST00000600118(transcript)|ensembl:ENST00000601220(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0010324"(membrane invagination)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903723"(negative regulation of centriole elongation)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|mint:O43633|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-432720|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-48533N - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:S5uZThg//3igYMf6LLYDJ/FVGRA9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:O14745 intact:EBI-25475909 intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376016|imex:IM-28441-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N - - - figure legend:Table 2, no 27|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:03E30U6coFBcC3BeKOYnInfG/BI9606 rigid:j+bbCRkjAfXuygf14iBhDT36llg false strep tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9Y3A6 intact:EBI-25475917 intact:EBI-7560959|intact:MINT-3085589|uniprotkb:B2R703|uniprotkb:D3DT38|uniprotkb:Q96AX8|uniprotkb:B1AKT4|ensembl:ENSP00000359305 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:tmed5_human(display_long)|uniprotkb:TMED5(gene name)|psi-mi:TMED5(display_short)|uniprotkb:p24 family protein gamma-2(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:CGI-100(orf name)|uniprotkb:UNQ397/PRO733(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_001161302.1|refseq:NP_057124.3|ensembl:ENSG00000117500(gene)|ensembl:ENST00000370282(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR009038(GOLD)|interpro:IPR015717(ST2 receptor binding protein related)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q9Y3A6|reactome:R-HSA-3238698 - - comment:mint|comment:homomint figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:3XAcqSucHNP4F3ilaBFRMSQ1B8Q9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q2PZI1 intact:EBI-25475917 intact:EBI-6164516|ensembl:ENSP00000308695|uniprotkb:O94954|uniprotkb:Q4G151 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:d19l1_human(display_long)|uniprotkb:Protein dpy-19 homolog 1(gene name synonym)|uniprotkb:DPY19L1(gene name)|psi-mi:DPY19L1(display_short)|uniprotkb:Dpy-19-like protein 1(gene name synonym)|uniprotkb:GA0500(gene name synonym)|uniprotkb:KIAA0877(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 ensembl:ENSG00000173852(gene)|ensembl:ENST00000310974(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|interpro:IPR018732|interpro:IPR030041|go:"GO:0000030"(mannosyltransferase activity)|refseq:NP_056098.1 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:JnDZiz7UFIUQvuIps5neyIQulsY9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q96S52 intact:EBI-25475917 intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9Y6M9 intact:EBI-25475917 intact:EBI-713654|uniprotkb:Q9UQE8|uniprotkb:B2R8M6|ensembl:ENSP00000276689|ensembl:ENSP00000504235 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:ndub9_human(display_long)|uniprotkb:LYRM3(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B22 subunit(gene name synonym)|uniprotkb:Complex I-B22(gene name synonym)|uniprotkb:LYR motif-containing protein 3(gene name synonym)|uniprotkb:NDUFB9(gene name)|psi-mi:NDUFB9(display_short)|uniprotkb:UQOR22(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 rcsb pdb:5XTH|rcsb pdb:5XTD|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000147684(gene)|ensembl:ENST00000276689(transcript)|ensembl:ENST00000677021(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR033034|mint:Q9Y6M9|rcsb pdb:5XTC|refseq:NP_001298097.1|refseq:NP_004996.1 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:sNQcYhIFMHZA5T6MeeiwAeAJ5Gs9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9Y375 intact:EBI-25475917 intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9Y276 intact:EBI-25475917 intact:EBI-719257|uniprotkb:B3KTW9|uniprotkb:Q7Z2V7|ensembl:ENSP00000352219|ensembl:ENSP00000375957|ensembl:ENSP00000375958|ensembl:ENSP00000375959|ensembl:ENSP00000404999|ensembl:ENSP00000406494|ensembl:ENSP00000413908 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:bcs1_human(display_long)|uniprotkb:BCS1-like protein(gene name synonym)|uniprotkb:BCS1L(gene name)|psi-mi:BCS1L(display_short)|uniprotkb:BCS1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_001073335.1|refseq:NP_004319.1|ensembl:ENSG00000074582(gene)|ensembl:ENST00000359273(transcript)|ensembl:ENST00000392109(transcript)|ensembl:ENST00000392110(transcript)|ensembl:ENST00000392111(transcript)|ensembl:ENST00000412366(transcript)|ensembl:ENST00000431802(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR014851(BCS1 N terminal)|interpro:IPR027417|reactome:R-HSA-1268020|ensembl:ENST00000439945(transcript)|refseq:NP_001244271.1|refseq:NP_001244272.1|refseq:NP_001244273.1|refseq:NP_001305765.1|refseq:NP_001307646.1|refseq:XP_006712741.1|refseq:XP_016860120.1|refseq:XP_016860121.1 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:NMfoX75THfvFwzpgBcpKXGmRGcM9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9NV92 intact:EBI-25475917 intact:EBI-2933200|ensembl:ENSP00000218652|ensembl:ENSP00000480798|uniprotkb:Q7Z2H3|uniprotkb:Q7Z428|uniprotkb:Q8TAR3|uniprotkb:Q9ULQ5 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:nfip2_human(display_long)|uniprotkb:NDFIP2(gene name)|psi-mi:NDFIP2(display_short)|uniprotkb:KIAA1165(gene name synonym)|uniprotkb:N4WBP5A(gene name synonym)|uniprotkb:NEDD4 WW domain-binding protein 5A(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM04/PM05/PM06/PM07(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 413(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 go:"GO:0050699"(WW domain binding)|go:"GO:0051224"(negative regulation of protein transport)|interpro:IPR019325|ensembl:ENSG00000102471(gene)|ensembl:ENST00000218652(transcript)|ensembl:ENST00000612570(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007034"(vacuolar transport)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030001"(metal ion transport)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032410"(negative regulation of transporter activity)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_061953.2|ensembl:ENSP00000218652|ensembl:ENSP00000480798 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:DfkxHtCVPGS8c26KDWG7mvPfDVU9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9H845 intact:EBI-25475917 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9H3K2 intact:EBI-25475917 intact:EBI-2868909|uniprotkb:A8K9Z9|uniprotkb:Q5VT95|uniprotkb:O95894|uniprotkb:Q9H0P2|uniprotkb:D3DWE0|ensembl:ENSP00000361207 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:ghitm_human(display_long)|uniprotkb:GHITM(gene name)|psi-mi:GHITM(display_short)|uniprotkb:DERP2(gene name synonym)|uniprotkb:MICS1(gene name synonym)|uniprotkb:TMBIM5(gene name synonym)|uniprotkb:Dermal papilla-derived protein 2(gene name synonym)|uniprotkb:Mitochondrial morphology and cristae structure 1(gene name synonym)|uniprotkb:Transmembrane BAX inhibitor motif-containing protein 5(gene name synonym)|uniprotkb:My021(orf name)|uniprotkb:UNQ244/PRO281(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_055209.2|ensembl:ENSG00000165678(gene)|ensembl:ENST00000372134(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR006214(Protein of unknown function UPF0005)|interpro:IPR035871|mint:Q9H3K2 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:HlNwyLRPIHhjs1bYJQE+IqZ00qc9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9GZU3 intact:EBI-25475917 intact:EBI-726099|uniprotkb:Q6IA44|uniprotkb:B4DKN8|uniprotkb:B4DQE6|uniprotkb:B4DTN8|uniprotkb:D3DPP4|ensembl:ENSP00000338165 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:tm39b_human(display_long)|uniprotkb:TMEM39B(gene name)|psi-mi:TMEM39B(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_060526.2|refseq:XP_011539986.1|refseq:NP_001306606.1|refseq:NP_001306607.1|refseq:NP_001306608.1|ensembl:ENSG00000121775(gene)|ensembl:ENST00000336294(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019397 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:zN/VSYfSC/5K0ey9Lx1NLzB41289606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9BVK2 intact:EBI-25475917 intact:EBI-3921603|intact:EBI-11062071|uniprotkb:O60860|ensembl:ENSP00000299626|uniprotkb:A6NDW6 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:alg8_human(display_long)|uniprotkb:ALG8(gene name)|psi-mi:ALG8(display_short)|uniprotkb:"Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase"(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 8 homolog(gene name synonym)|uniprotkb:"Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase"(gene name synonym)|uniprotkb:HUSSY-02(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_076984.2|refseq:NP_001007028.1|ensembl:ENSG00000159063(gene)|ensembl:ENST00000299626(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0004583"(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0006490"(oligosaccharide-lipid intermediate biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042283"(dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity)|interpro:IPR004856(ALG6, ALG8 glycosyltransferase)|interpro:IPR039487|reactome:R-HSA-446193|reactome:R-HSA-4724325 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:BK26e5oFe7JV7sQ9B6S1psk8bL89606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q9BQ95 intact:EBI-25475917 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q96K12 intact:EBI-25475917 intact:EBI-4280043|uniprotkb:Q9H0D5|uniprotkb:Q9NVW8|ensembl:ENSP00000182377|ensembl:ENSP00000443291|uniprotkb:F8VV73 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:facr2_human(display_long)|uniprotkb:FAR2(gene name)|psi-mi:FAR2(display_short)|uniprotkb:MLSTD1(gene name synonym)|uniprotkb:Male sterility domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_060569.3|ensembl:ENSG00000064763(gene)|ensembl:ENST00000182377(transcript)|ensembl:ENST00000536681(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0010025"(wax biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR033640|interpro:IPR036291|reactome:R-HSA-9640463|refseq:NP_001258712.1 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:4cd4XkEREQXRcJU05tvEtZQUlU49606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q8TEQ8 intact:EBI-25475917 intact:EBI-11722765|uniprotkb:B1AML3|uniprotkb:Q6P154|uniprotkb:Q6UX80|uniprotkb:Q8TDS8|uniprotkb:Q96CS9|uniprotkb:Q9BVN9|uniprotkb:Q9Y4B0|ensembl:ENSP00000367880 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:pigo_human(display_long)|uniprotkb:PIGO(gene name)|psi-mi:PIGO(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class O protein(gene name synonym)|uniprotkb:UNQ632/PRO1249(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_001188413.1|refseq:NP_116023.2|refseq:NP_690577.2|refseq:XP_005251676.1|refseq:XP_016870711.1|refseq:XP_016870712.1|refseq:XP_016870713.1|ensembl:ENSG00000165282(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051377"(mannose-ethanolamine phosphotransferase activity)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR037675|interpro:IPR039524|reactome:R-HSA-162710|ensembl:ENST00000378617(transcript) - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:WGLdye0wC84/xsJ6DbkSRdB3Q/U9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q86VR2 intact:EBI-25475917 intact:EBI-10192441|uniprotkb:B3KR75|intact:EBI-28968873|ensembl:ENSP00000309432 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:retr3_human(display_long)|uniprotkb:RETREG3(gene name)|psi-mi:RETREG3(display_short)|uniprotkb:FAM134C(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 ensembl:ENSP00000309432|refseq:NP_835227.1|ensembl:ENSG00000141699(gene)|ensembl:ENST00000309428(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061709"(reticulophagy)|interpro:IPR033361|interpro:IPR043384|dip:DIP-61578N - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:KqWyZAyKEB6J9lUId4BSZK2nQXQ9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q86UT6 intact:EBI-25475917 intact:EBI-3893071|uniprotkb:A8K6Q1|uniprotkb:B3KPK2|uniprotkb:B3KTA2|uniprotkb:Q7RTR3|uniprotkb:Q96D51|uniprotkb:Q9H724|ensembl:ENSP00000292199|ensembl:ENSP00000386851|ensembl:ENSP00000386858|ensembl:ENSP00000387334 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:nlrx1_human(display_long)|uniprotkb:NLRX1(gene name)|psi-mi:NLRX1(display_short)|uniprotkb:NOD26(gene name synonym)|uniprotkb:NOD5(gene name synonym)|uniprotkb:NOD9(gene name synonym)|uniprotkb:Caterpiller protein 11.3(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 26(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 5(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 9(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:XP_006718967.1|refseq:XP_011541282.1|refseq:NP_078894.2|dip:DIP-60637N|refseq:NP_001269072.1|refseq:NP_001269073.1|refseq:NP_001269287.1|refseq:XP_005271726.1|ensembl:ENSG00000160703(gene)|ensembl:ENST00000292199(transcript)|ensembl:ENST00000409109(transcript)|ensembl:ENST00000409265(transcript)|ensembl:ENST00000409991(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|rcsb pdb:3UN9|reactome:R-HSA-168928|reactome:R-HSA-936440|go:"GO:0030054"(cell junction) - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:w+BOLVATt2ey/lEP6RY9zP2q/gc9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q7Z2K6 intact:EBI-25475917 intact:EBI-10976398|ensembl:ENSP00000340427|ensembl:ENSP00000417160|uniprotkb:B3KSB1|uniprotkb:B2RNA4|uniprotkb:Q9H5M1|uniprotkb:Q8N5T5 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:ermp1_human(display_long)|uniprotkb:ERMP1(gene name)|psi-mi:ERMP1(display_short)|uniprotkb:FXNA(gene name synonym)|uniprotkb:Felix-ina(gene name synonym)|uniprotkb:KIAA1815(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_079172.2|ensembl:ENSG00000099219(gene)|ensembl:ENST00000339450(transcript)|ensembl:ENST00000462592(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|interpro:IPR007484(Peptidase M28)|mint:Q7Z2K6 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:KTUjM61VKt7x03WaW4M8L0OkaJ49606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q6NXT6 intact:EBI-25475917 intact:EBI-11126842|uniprotkb:Q9NZK9|uniprotkb:Q8N2S3|ensembl:ENSP00000385347 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:tapt1_human(display_long)|uniprotkb:TAPT1(gene name)|psi-mi:TAPT1(display_short)|uniprotkb:CMVFR(gene name synonym)|uniprotkb:Cytomegalovirus partial fusion receptor(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_699196.2|ensembl:ENSG00000169762(gene)|ensembl:ENST00000405303(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005813"(centrosome)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016520"(growth hormone-releasing hormone receptor activity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:1903012"(positive regulation of bone development)|interpro:IPR008010(Protein of unknown function DUF747, CMV receptor) - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:UK0TKC4tFkmRvuW2HJtBzG7+GL89606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q6NXT4 intact:EBI-25475917 intact:EBI-2849005|uniprotkb:Q96NC3|uniprotkb:A5YM45|uniprotkb:Q8N5C9|uniprotkb:B7Z901|ensembl:ENSP00000282587 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:znt6_human(display_long)|uniprotkb:SLC30A6(gene name)|psi-mi:SLC30A6(display_short)|uniprotkb:ZNT6(gene name synonym)|uniprotkb:Solute carrier family 30 member 6(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_001180442.1|refseq:NP_001180443.1|refseq:NP_060434.2|refseq:NP_001180444.1|ensembl:ENSG00000152683(gene)|ensembl:ENST00000282587(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|reactome:R-HSA-264876|reactome:R-HSA-435368 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:87Lnmo7ZMC5jeA4yaMQdauspboE9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q5BJF2 intact:EBI-25475917 intact:EBI-12111910|ensembl:ENSP00000226230|uniprotkb:B4DS02|uniprotkb:Q07823 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:sgmr2_human(display_long)|uniprotkb:TMEM97(gene name)|psi-mi:TMEM97(display_short)|uniprotkb:MAC30(gene name synonym)|uniprotkb:Meningioma-associated protein 30(gene name synonym)|uniprotkb:S2R(gene name synonym)|uniprotkb:Transmembrane protein 97(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042632"(cholesterol homeostasis)|interpro:IPR016964(Transmembrane protein 97, predicted)|interpro:IPR033118|mint:Q5BJF2|go:"GO:0016021"(integral component of membrane)|ensembl:ENSG00000109084(gene)|ensembl:ENST00000226230(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|refseq:NP_055388.2 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:fAHmQ+5mzpFzsbwgChR6pZAHJtE9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:Q12770 intact:EBI-25475917 intact:EBI-6190187|ensembl:ENSP00000265565|ensembl:ENSP00000497087|uniprotkb:Q8N2E0|uniprotkb:Q8WUA1 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:scap_human(display_long)|uniprotkb:SCAP(gene name)|psi-mi:SCAP(display_short)|uniprotkb:KIAA0199(gene name synonym)|uniprotkb:PSEC0227(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 ensembl:ENSG00000114650(gene)|ensembl:ENST00000648151(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006955"(immune response)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032934"(sterol binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|ensembl:ENST00000265565(transcript)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR030225|interpro:IPR036322|mint:Q12770|rcsb pdb:6M49|rcsb pdb:7ETW|reactome:R-HSA-1655829|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|refseq:XP_011531803.1|refseq:NP_036367.2|refseq:XP_016861407.1|refseq:XP_016861410.1 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:bhavwLS6XzkZpAoBhCsII97JfpI9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:P55085 intact:EBI-25475917 intact:EBI-4303189|uniprotkb:Q13317|uniprotkb:Q13346|ensembl:ENSP00000296677|uniprotkb:Q53XJ8 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:par2_human(display_long)|uniprotkb:F2RL1(gene name)|psi-mi:F2RL1(display_short)|uniprotkb:GPR11(gene name synonym)|uniprotkb:PAR2(gene name synonym)|uniprotkb:Coagulation factor II receptor-like 1(gene name synonym)|uniprotkb:G-protein coupled receptor 11(gene name synonym)|uniprotkb:Thrombin receptor-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_005233.3|ensembl:ENSG00000164251(gene)|ensembl:ENST00000296677(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015057"(thrombin-activated receptor activity)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031143"(pseudopodium)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034140"(negative regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042119"(neutrophil activation)|go:"GO:0042311"(vasodilation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070661"(leukocyte proliferation)|go:"GO:0070963"(positive regulation of neutrophil mediated killing of gram-negative bacterium)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:1900135"(positive regulation of renin secretion into blood stream)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR002281(Protease-activated receptor 2)|interpro:IPR003912(Protease-activated receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P55085|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|reactome:R-HSA-375276|reactome:R-HSA-416476|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032722"(positive regulation of chemokine production)|dip:DIP-42044N - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:j9cMnyj9C74tReGYkQvGFy+cez49606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:P33527 intact:EBI-25475917 intact:EBI-3911547|uniprotkb:O14819|uniprotkb:Q9UQ99|uniprotkb:P78419|uniprotkb:A3RJX2|uniprotkb:Q59GI9|uniprotkb:O43333|uniprotkb:Q9UQ97|uniprotkb:Q9UQA0|uniprotkb:C9JPJ4|ensembl:ENSP00000382342|ensembl:ENSP00000483316 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:mrp1_human(display_long)|uniprotkb:ABCC1(gene name)|psi-mi:ABCC1(display_short)|uniprotkb:MRP(gene name synonym)|uniprotkb:MRP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 1(gene name synonym)|uniprotkb:"Leukotriene C(4) transporter"(gene name synonym)|uniprotkb:Glutathione-S-conjugate-translocating ATPase ABCC1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_004987.2|ensembl:ENSG00000103222(gene)|ensembl:ENSG00000278183(gene)|ensembl:ENST00000399410(transcript)|ensembl:ENST00000621144(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015420"(ABC-type vitamin B12 transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0034040"(ATPase-coupled lipid transmembrane transporter activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0034775"(glutathione transmembrane transport)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0099039"(sphingolipid translocation)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0140359"(ABC-type transporter activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905039"(carboxylic acid transmembrane transport)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292("Multi drug resistance-associated protein (MRP)")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P33527|rcsb pdb:2CBZ|rcsb pdb:4C3Z|reactome:R-HSA-196741|reactome:R-HSA-2142691|reactome:R-HSA-382556|reactome:R-HSA-9707564|reactome:R-HSA-189483 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:XGzXibUwQjwbAsg7ueuXS9YxUVc9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:O76024 intact:EBI-25475917 intact:EBI-720609|uniprotkb:Q8N6I3|uniprotkb:Q9UNW6|uniprotkb:B2R797|uniprotkb:D3DVT1|ensembl:ENSP00000226760|ensembl:ENSP00000423337|ensembl:ENSP00000506978 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:wfs1_human(display_long)|uniprotkb:WFS1(gene name)|psi-mi:WFS1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1903892"(negative regulation of ATF6-mediated unfolded protein response)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR026208|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050877"(nervous system process)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070628"(proteasome binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR026209|refseq:NP_001139325.1|refseq:NP_005996.2|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030141"(secretory granule)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000109501(gene)|ensembl:ENST00000226760(transcript)|ensembl:ENST00000503569(transcript)|ensembl:ENST00000684087(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001822"(kidney development)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|mint:O76024 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:bt4NKJUKyrQeJ8emdvrT3sg0Rf49606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:O00124 intact:EBI-25475917 intact:EBI-1993850|uniprotkb:Q7Z6F2 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:ubxn8_human(display_long)|uniprotkb:UBXN8(gene name)|psi-mi:UBXN8(display_short)|uniprotkb:D8S2298E(gene name synonym)|uniprotkb:REP8(gene name synonym)|uniprotkb:UBXD6(gene name synonym)|uniprotkb:UBX domain-containing protein 6(gene name synonym)|uniprotkb:Reproduction 8 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_005662.1|interpro:IPR001012(UBX)|interpro:IPR017247(UBX , Rep6)|interpro:IPR029071|refseq:NP_001269118.1|refseq:NP_001269128.1|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007338"(single fertilization)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity) - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:trPGnzbb5gS67+tqyKRObciKV8M9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD3 uniprotkb:O43292 intact:EBI-25475917 intact:EBI-720225|uniprotkb:Q9NSS0|uniprotkb:Q9UQ31|ensembl:ENSP00000347206 psi-mi:orf9c_sars2(display_long)|uniprotkb:Uncharacterized protein 14(gene name synonym)|uniprotkb:9c(orf name) psi-mi:gpaa1_human(display_long)|uniprotkb:GAA1 protein homolog(gene name synonym)|uniprotkb:GPAA1(gene name)|psi-mi:GPAA1(display_short)|uniprotkb:GAA1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376038|imex:IM-28441-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|interpro:IPR035113 refseq:NP_003792.1|ensembl:ENSG00000197858(gene)|ensembl:ENST00000355091(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007246(Gaa1-like, GPI transamidase component)|mint:O43292|reactome:R-HSA-162791 - - - figure legend:Table 2, no 28|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/20 rogid:buoPXGEhYOzLcuVHh/3HXXRCzA82697049 rogid:rAbNrvIdzfJFRNTZ5qxulRrc/KQ9606 rigid:aNOfSmz2pdiS+CIKY8pdtB6EFIM false strep tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59637 uniprotkb:Q92665 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397 psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376480|imex:IM-28441-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table 2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606 rigid:dPbxn6l2R0hrYYLIR1J1llPwZJo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59637 uniprotkb:Q9ULP9 intact:EBI-25487741|uniprotkb:Q7TA13|uniprotkb:Q7TFA8 intact:EBI-11277385|uniprotkb:A0JNW3|uniprotkb:B9A6M6|uniprotkb:Q2KJ08|ensembl:ENSP00000494678 psi-mi:vemp_sars(display_long)|uniprotkb:E(gene name)|psi-mi:E(display_short)|uniprotkb:sM(gene name synonym)|uniprotkb:4(orf name) psi-mi:tbc24_human(display_long)|uniprotkb:TBC1D24(gene name)|psi-mi:TBC1D24(display_short)|uniprotkb:KIAA1171(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376480|imex:IM-28441-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|rcsb pdb:7NTJ|go:"GO:0000139"(Golgi membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044662"(disruption by virus of host cell membrane)|go:"GO:0046760"(viral budding from Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044377|rcsb pdb:2MM4|rcsb pdb:5X29|rcsb pdb:5XER|rcsb pdb:5XES|interpro:IPR003873(Nonstructural protein NS3/small envelope protein E)|interpro:IPR043506|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683683|reactome:R-HSA-9683701|refseq:NP_828854.1 refseq:NP_001186036.1|refseq:NP_065756.1|ensembl:ENSG00000162065(gene)|ensembl:ENST00000646147(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0016358"(dendrite development)|go:"GO:0030054"(cell junction)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043195"(terminal bouton)|go:"GO:0098794"(postsynapse)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR006571(TLDc)|interpro:IPR035969|interpro:IPR040149|reactome:R-HSA-8854214|refseq:XP_016878982.1|refseq:XP_016878983.1|refseq:XP_016878984.1 - - - figure legend:Table 2, no 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:RohltRPJbmvNaZQpQQDxwwUkjd0694009 rogid:F94mUX64NxHOajgJSvlvJz63sfY9606 rigid:dPbxn6l2R0hrYYLIR1J1llPwZJo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9BXW9 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-359343|uniprotkb:Q2LA86|uniprotkb:Q69YP9|uniprotkb:Q6PJN7|uniprotkb:Q9BQ06|uniprotkb:Q9H9T9|ensembl:ENSP00000398754|ensembl:ENSP00000502379 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:facd2_human(display_long)|uniprotkb:FANCD2(gene name)|psi-mi:FANCD2(display_short)|uniprotkb:FACD(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001018125.1|refseq:NP_149075.2|refseq:NP_001306913.1|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|interpro:IPR029448|mint:Q9BXW9|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|ensembl:ENSG00000144554(gene)|ensembl:ENST00000419585(transcript)|ensembl:ENST00000675286(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0016604"(nuclear body)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0036297"(interstrand cross-link repair)|reactome:R-HSA-6796648|rcsb pdb:7KZQ|rcsb pdb:7KZR|rcsb pdb:7KZS|rcsb pdb:7KZT|rcsb pdb:7KZV|reactome:R-HSA-6783310|dip:DIP-27606N|dip:DIP-29382N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:9szrKioB24vbUy47a30DPUQhqkA9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9Y5Y0 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-9681535|uniprotkb:Q1HE16|uniprotkb:Q86XY9|uniprotkb:Q9NVR9|ensembl:ENSP00000355938 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:flvc1_human(display_long)|uniprotkb:FLVCR1(gene name)|psi-mi:FLVCR1(display_short)|uniprotkb:FLVCR(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_054772.1|ensembl:ENSG00000162769(gene)|ensembl:ENST00000366971(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048536"(spleen development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060323"(head morphogenesis)|go:"GO:0097037"(heme export)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|mint:Q9Y5Y0|reactome:R-HSA-189451|reactome:R-HSA-917937 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:bb6L2akAjb64NgdW94M2I3uMhxQ9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9Y4R8 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1043674|uniprotkb:O75168|uniprotkb:Q7LDV4|uniprotkb:Q9BR21|intact:EBI-725566|intact:EBI-1047721|ensembl:ENSP00000262319|uniprotkb:D3DU73 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:telo2_human(display_long)|uniprotkb:TELO2(gene name)|psi-mi:TELO2(display_short)|uniprotkb:KIAA0683(gene name synonym)|uniprotkb:Protein clk-2 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000100726(gene)|ensembl:ENST00000262319(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070209"(ASTRA complex)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019337|interpro:IPR038528|mint:Q9Y4R8|rcsb pdb:4PSI|refseq:NP_057195.2|refseq:XP_016879403.1|dip:DIP-40568N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:AnKk5b5Bc/tzEEz+p68m5uQUZVY9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9ULF5 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2823223|uniprotkb:B4DGU0|uniprotkb:A8K5C6|uniprotkb:Q3MJA4|uniprotkb:Q6DKH6|uniprotkb:Q68CR5|uniprotkb:Q9Y3Z1|ensembl:ENSP00000352655|ensembl:ENSP00000386766 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:s39aa_human(display_long)|uniprotkb:SLC39A10(gene name)|psi-mi:SLC39A10(display_short)|uniprotkb:KIAA1265(gene name synonym)|uniprotkb:ZIP10(gene name synonym)|uniprotkb:Solute carrier family 39 member 10(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:XP_011509806.1|refseq:XP_011509807.1|refseq:XP_011509808.1|refseq:XP_005246746.2|refseq:NP_001120729.1|refseq:NP_065075.1|ensembl:ENSG00000196950(gene)|ensembl:ENST00000359634(transcript)|ensembl:ENST00000409086(transcript)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0071578"(zinc ion import across plasma membrane)|go:"GO:1903615"(positive regulation of protein tyrosine phosphatase activity)|interpro:IPR003689(Zinc/iron permease)|reactome:R-HSA-442380 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:j7A/tPe/lJCOscfBZhF1mSe99k09606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9UKV5 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9UBF2 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9P2R7 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9NVI1 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9NVH2 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11276282|uniprotkb:B4DLZ6|uniprotkb:B7WNP6|uniprotkb:B7WPB6|uniprotkb:Q8N4K7|uniprotkb:Q8WUH5|uniprotkb:Q9H9V3|uniprotkb:Q9NVU5|uniprotkb:Q9UFC6|uniprotkb:Q9UFM3|ensembl:ENSP00000355961 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:int7_human(display_long)|uniprotkb:INTS7(gene name)|psi-mi:INTS7(display_short)|uniprotkb:C1orf73(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001186738.1|refseq:NP_001186740.1|refseq:NP_001186741.1|refseq:NP_056249.1|ensembl:ENSG00000143493(gene)|ensembl:ENST00000366994(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033060|mint:Q9NVH2|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:PqhjJZUeAkdQHmckoWrwfsPUUeI9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9H8M5 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11343456|uniprotkb:Q9NXT4|uniprotkb:Q9NRK5|uniprotkb:Q9H952|uniprotkb:Q8WU59|uniprotkb:Q5T570|uniprotkb:Q5T569|ensembl:ENSP00000358894 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:cnnm2_human(display_long)|uniprotkb:CNNM2(gene name)|psi-mi:CNNM2(display_short)|uniprotkb:ACDP2(gene name synonym)|uniprotkb:Ancient conserved domain-containing protein 2(gene name synonym)|uniprotkb:Cyclin-M2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_060119.3|refseq:NP_951058.1|refseq:NP_951059.1|ensembl:ENSG00000148842(gene)|ensembl:ENST00000369878(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR044751|rcsb pdb:4IY0|rcsb pdb:4IY2|rcsb pdb:4IY4|rcsb pdb:4IYS|rcsb pdb:6DJ3|rcsb pdb:6N7E - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:CS9mrMfLOgewPqJjrIIHajo7uN89606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9H845 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9H7F0 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11722593|uniprotkb:Q8NC11|uniprotkb:Q96KS1|ensembl:ENSP00000416508|ensembl:ENSP00000494471 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:at133_human(display_long)|uniprotkb:ATP13A3(gene name)|psi-mi:ATP13A3(display_short)|uniprotkb:AFURS1(gene name synonym)|uniprotkb:ATPase family homolog up-regulated in senescence cells 1(gene name synonym)|uniprotkb:Putrescine transporting ATPase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_078800.3|refseq:XP_011511425.1|ensembl:ENSG00000133657(gene)|ensembl:ENST00000439040(transcript)|ensembl:ENST00000645538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015594"(ABC-type putrescine transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:rfv5ILI3FtufMHip3E0FrxmCTvI9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9H583 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1048716|uniprotkb:Q5T3Q8|uniprotkb:Q6P197|uniprotkb:Q9NW23|ensembl:ENSP00000355541 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:heat1_human(display_long)|uniprotkb:Protein BAP28(gene name synonym)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)|uniprotkb:BAP28(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 10 homolog(gene name synonym)|uniprotkb:UTP10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_060542.4|ensembl:ENSG00000119285(gene)|ensembl:ENST00000366582(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022125|interpro:IPR040191|mint:Q9H583|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:0WoP84UUVfXWppmvCYa/n5GTzc89606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9H2J7 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11343466|uniprotkb:E7ESJ5|uniprotkb:B7Z2P7|uniprotkb:A8K592|uniprotkb:Q9H9F5|ensembl:ENSP00000266682|ensembl:ENSP00000505286|ensembl:ENSP00000505485|ensembl:ENSP00000505789 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:s6a15_human(display_long)|uniprotkb:SLC6A15(gene name)|psi-mi:SLC6A15(display_short)|uniprotkb:B0AT2(gene name synonym)|uniprotkb:NTT73(gene name synonym)|uniprotkb:SBAT1(gene name synonym)|uniprotkb:Sodium- and chloride-dependent neurotransmitter transporter NTT73(gene name synonym)|uniprotkb:Sodium-coupled branched-chain amino-acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 6 member 15(gene name synonym)|uniprotkb:Transporter v7-3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001139807.1|refseq:NP_060527.2|refseq:NP_877499.1|ensembl:ENSG00000072041(gene)|ensembl:ENST00000266682(transcript)|ensembl:ENST00000680963(transcript)|ensembl:ENST00000681106(transcript)|ensembl:ENST00000681721(transcript)|go:"GO:0005298"("proline:sodium symporter activity")|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0015820"(leucine transport)|go:"GO:0015824"(proline transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002438("Sodium:neurotransmitter symporter, orphan")|interpro:IPR037272|interpro:IPR042934|reactome:R-HSA-352230|reactome:R-HSA-442660 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:MubTClioe24j6+ldJKeHsmuzg1U9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9GZM5 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-743787|uniprotkb:Q5JTD2|uniprotkb:Q6FI85|uniprotkb:Q8NI57|uniprotkb:Q9NWE3|uniprotkb:Q9Y3U9|ensembl:ENSP00000361499 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:yipf3_human(display_long)|uniprotkb:YIP1 family member 3(gene name synonym)|uniprotkb:Killer lineage protein 1(gene name synonym)|uniprotkb:Natural killer cell-specific antigen KLIP1(gene name synonym)|uniprotkb:YIPF3(gene name)|psi-mi:YIPF3(display_short)|uniprotkb:C6orf109(gene name synonym)|uniprotkb:KLIP1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_056203.2|ensembl:ENSG00000137207(gene)|ensembl:ENST00000372422(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR026637|mint:Q9GZM5 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:TivdjV9up3Yri6QTp1vLRgGcE0A9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9C0E2 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9C0D9 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-3920260|intact:EBI-28977331|ensembl:ENSP00000260585|uniprotkb:Q63ZE3 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ept1_human(display_long)|uniprotkb:SELENOI(gene name)|psi-mi:SELENOI(display_short)|uniprotkb:EPT1(gene name synonym)|uniprotkb:KIAA1724(gene name synonym)|uniprotkb:SELI(gene name synonym)|uniprotkb:Selenoprotein I(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000138018(gene)|ensembl:ENST00000260585(transcript)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-HSA-1483213|ensembl:ENSP00000260585|refseq:NP_277040.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:bXSfbVL2XLRnKK6l7ICjC8Z7wKw9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9BTY2 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-9050116|uniprotkb:E9PEB6|uniprotkb:Q7Z6V1|uniprotkb:Q7Z6Y2|uniprotkb:Q8NBK4|ensembl:ENSP00000002165 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:fuco2_human(display_long)|uniprotkb:FUCA2(gene name)|psi-mi:FUCA2(display_short)|uniprotkb:Alpha-L-fucoside fucohydrolase 2(gene name synonym)|uniprotkb:PSEC0151(orf name)|uniprotkb:UNQ227/PRO260(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_114409.2|ensembl:ENSG00000001036(gene)|ensembl:ENST00000002165(transcript)|go:"GO:0004560"(alpha-L-fucosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006004"(fucose metabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR000933("Glycoside hydrolase, family 29 (alpha-L-fucosidase)")|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR016286(Alpha-L-fucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018526|interpro:IPR031919|reactome:R-HSA-381426|reactome:R-HSA-6798695|reactome:R-HSA-8957275 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:cBWxxpX9fUF1KQjkaIWoq2n0Vqg9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9BSJ2 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-357881|uniprotkb:O43632|ensembl:ENSP00000252936|ensembl:ENSP00000506731|ensembl:ENSP00000507482|ensembl:ENSP00000507610|uniprotkb:Q5VWX7|uniprotkb:B4DM18|uniprotkb:F5H4E0|uniprotkb:B7ZKL8|uniprotkb:F5H4L0 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:gcp2_human(display_long)|uniprotkb:TUBGCP2(gene name)|psi-mi:TUBGCP2(display_short)|uniprotkb:GCP2(gene name synonym)|uniprotkb:Spindle pole body protein Spc97 homolog(gene name synonym)|uniprotkb:Gamma-ring complex protein 103 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_006650.1|ensembl:ENSG00000130640(gene)|ensembl:ENST00000252936(transcript)|ensembl:ENST00000682123(transcript)|ensembl:ENST00000682515(transcript)|ensembl:ENST00000683612(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0001764"(neuron migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001243547.1|refseq:NP_001243546.1|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007420"(brain development)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q9BSJ2|rcsb pdb:6V6B|rcsb pdb:6V6S|rcsb pdb:6X0V|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:vhamYv9ZNsZkSBkGQCwVylqx9wE9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q9BQ95 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q99805 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2852254|uniprotkb:Q2TAY5|uniprotkb:A8K399|ensembl:ENSP00000365567|ensembl:ENSP00000493515 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:tm9s2_human(display_long)|uniprotkb:TM9SF2(gene name)|psi-mi:TM9SF2(display_short)|uniprotkb:p76(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_004791.1|ensembl:ENSG00000125304(gene)|ensembl:ENST00000376387(transcript)|ensembl:ENST00000642475(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q99805 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:qg5QSnzX8+4H0Nfab7Ci9n9igc09606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q96D53 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q96CW5 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1046278|ensembl:ENSP00000261965|uniprotkb:O43631|uniprotkb:O60852|uniprotkb:O60853|uniprotkb:Q7Z4K1|uniprotkb:Q96I79|uniprotkb:Q5T8L2 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:gcp3_human(display_long)|uniprotkb:Spindle pole body protein Spc98 homolog(gene name synonym)|uniprotkb:TUBGCP3(gene name)|psi-mi:TUBGCP3(display_short)|uniprotkb:GCP3(gene name synonym)|uniprotkb:Gamma-ring complex protein 104 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007338"(single fertilization)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q96CW5|rcsb pdb:6V6B|go:"GO:0000930"(gamma-tubulin complex)|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|ensembl:ENSG00000126216(gene)|ensembl:ENST00000261965(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000923"(equatorial microtubule organizing center)|refseq:NP_006313.1|refseq:NP_001273207.1|refseq:NP_001273208.1|refseq:NP_001273206.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:xt+Ngo2s/4djh2PnyMEaxgDyLrs9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q96AA3 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-6269616|ensembl:ENSP00000296292|uniprotkb:Q96J03 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:rft1_human(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000163933(gene)|ensembl:ENST00000296292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|mint:Q96AA3|reactome:R-HSA-446193|reactome:R-HSA-4570571|refseq:NP_443091.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:off+uN6MYDiLT5q1oh7G2sd6RXw9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q969V3 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1056979|uniprotkb:O75252|uniprotkb:Q6FI60|uniprotkb:Q6ZMB7|uniprotkb:Q8TAT7|uniprotkb:Q96H48|uniprotkb:Q96IS7|uniprotkb:Q9BQH9|uniprotkb:Q9BTX4|uniprotkb:Q9NPP2|uniprotkb:D6W613|ensembl:ENSP00000246117 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ncln_human(display_long)|uniprotkb:NCLN(gene name)|psi-mi:NCLN(display_short)|uniprotkb:Nicastrin-like protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_064555.2|refseq:NP_001308392.1|ensembl:ENSG00000125912(gene)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR007484(Peptidase M28)|interpro:IPR016574(Nicalin)|mint:Q969V3|rcsb pdb:6W6L|ensembl:ENST00000246117(transcript) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:h2Md0pyypG6ZFLWOxHxQvJKFg/k9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q92604 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-6116942|uniprotkb:Q53YL2|ensembl:ENSP00000355963|ensembl:ENSP00000355964 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:lgat1_human(display_long)|uniprotkb:LPGAT1(gene name)|psi-mi:LPGAT1(display_short)|uniprotkb:FAM34A(gene name synonym)|uniprotkb:KIAA0205(gene name synonym)|uniprotkb:"Acyl-CoA:monoacylglycerol acyltransferase LPGAT1"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:XP_011508530.1|refseq:XP_011508531.1|refseq:NP_001307737.1|refseq:NP_055688.1|ensembl:ENSG00000123684(gene)|ensembl:ENST00000366996(transcript)|ensembl:ENST00000366997(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0003846"(2-acylglycerol O-acyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0036148"(phosphatidylglycerol acyl-chain remodeling)|go:"GO:0036149"(phosphatidylinositol acyl-chain remodeling)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0071617"(lysophospholipid acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|mint:Q92604|reactome:R-HSA-1482925 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:9N2frmSoY9VESmi8Z3ERTo1L3CU9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q8WY22 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-359348|uniprotkb:Q8WY23|ensembl:ENSP00000340761|ensembl:ENSP00000500359 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:bri3b_human(display_long)|uniprotkb:BRI3BP(gene name)|psi-mi:BRI3BP(display_short)|uniprotkb:KG19(gene name synonym)|uniprotkb:Cervical cancer 1 proto-oncogene-binding protein KG19(gene name synonym)|uniprotkb:HCCRBP-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_542193.3|ensembl:ENSG00000184992(gene)|ensembl:ENST00000341446(transcript)|ensembl:ENST00000672415(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR033367 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:O9epHcfM1m7xNvrm6ELo0fRRGV49606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q8WUD6 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11337856|uniprotkb:Q7Z7H1|uniprotkb:Q8WYI4|uniprotkb:Q8IWQ5|uniprotkb:Q7Z7H0|uniprotkb:Q9NRQ6|uniprotkb:B3KQM2|uniprotkb:Q9Y6M6|uniprotkb:Q9NRQ7|uniprotkb:Q7Z7H2|uniprotkb:Q8IWQ4|ensembl:ENSP00000229266 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:chpt1_human(display_long)|uniprotkb:CHPT1(gene name)|psi-mi:CHPT1(display_short)|uniprotkb:AAPT1-like protein(gene name synonym)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:MSTP022(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_064629.2|ensembl:ENSG00000111666(gene)|ensembl:ENST00000229266(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0006663"(platelet activating factor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|mint:Q8WUD6|reactome:R-HSA-1483191 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:4RFBPd6zmk0NFjCdHC01wIXZd989606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q8TCJ2 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2256290|uniprotkb:Q96JZ4|uniprotkb:Q96KY7|ensembl:ENSP00000295770 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:stt3b_human(display_long)|uniprotkb:STT3B(gene name)|psi-mi:STT3B(display_short)|uniprotkb:SIMP(gene name synonym)|uniprotkb:Source of immunodominant MHC-associated peptides homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_849193.1|ensembl:ENSG00000163527(gene)|ensembl:ENST00000295770(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034998"(oligosaccharyltransferase I complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:Q8TCJ2|rcsb pdb:6S7T - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:4F+9LbIZTFRoczuphd1jzuhnFDo9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q8TBF5 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-25585044|ensembl:ENSP00000376192|uniprotkb:Q9NWZ2 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:pigx_human(display_long)|uniprotkb:PIGX(gene name)|psi-mi:PIGX(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000163964(gene)|ensembl:ENST00000392391(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013233(PIG-X/PBN1)|interpro:IPR040039|reactome:R-HSA-162710|refseq:NP_001159776.1|refseq:NP_060331.3 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:Zt8OEVCGCPGqmV3Jr1VM8IGojxM9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q8N5G2 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2683507|uniprotkb:Q2TLX5|uniprotkb:Q2TLX6|uniprotkb:B1AK00|uniprotkb:Q9NVG6|ensembl:ENSP00000363463 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:macoi_human(display_long)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:MACO1(gene name)|psi-mi:MACO1(display_short)|uniprotkb:TMEM57(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001269493.1|refseq:NP_060672.2|ensembl:ENSG00000204178(gene)|ensembl:ENST00000374343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030424"(axon)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130|reactome:R-HSA-8980692|reactome:R-HSA-9013106 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:k8wUq+ZSQRPwhRdj2c8pgzgQEgU9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q8N1F8 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2340204|uniprotkb:Q8NAW9|uniprotkb:Q96PY9|uniprotkb:Q8WXE4|uniprotkb:Q96CN3|uniprotkb:C9JQV3|ensembl:ENSP00000389383 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:s11ip_human(display_long)|uniprotkb:STK11IP(gene name)|psi-mi:STK11IP(display_short)|uniprotkb:KIAA1898(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:LKB1IP(gene name synonym)|uniprotkb:STK11IP1(gene name synonym)|uniprotkb:LKB1-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_443134.3|ensembl:ENSG00000144589(gene)|ensembl:ENST00000456909(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0008104"(protein localization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035578"(azurophil granule lumen)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR031782|interpro:IPR032675|mint:Q8N1F8|reactome:R-HSA-6798695 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:bkZvSPFpB2rsgtmUrzt1YPiGrp49606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q86UL3 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-3925330|uniprotkb:Q86V89|ensembl:ENSP00000380184|uniprotkb:Q2TU73 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:gpat4_human(display_long)|uniprotkb:GPAT4(gene name)|psi-mi:GPAT4(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 6(gene name synonym)|uniprotkb:AGPAT6(gene name synonym)|uniprotkb:"Acyl-CoA:glycerol-3-phosphate acyltransferase 4"(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase zeta(gene name synonym)|uniprotkb:TSARG7(gene name synonym)|uniprotkb:Testis spermatogenesis apoptosis-related protein 7(gene name synonym)|uniprotkb:UNQ551/PRO1108(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:XP_011542694.1|refseq:XP_011542695.1|refseq:XP_011542696.1|refseq:NP_848934.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007595"(lactation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0102420"("sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity")|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|reactome:R-HSA-1483166|ensembl:ENSG00000158669(gene)|ensembl:ENST00000396987(transcript)|go:"GO:0002071"(glandular epithelial cell maturation)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0004366"(glycerol-3-phosphate O-acyltransferase activity)|refseq:XP_016868531.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:0j/B1lxhVshCx6yA7HNCsemsuD49606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q7Z3U7 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-358882|uniprotkb:A5D8U7|uniprotkb:A7E2Y0|uniprotkb:Q86TA2|uniprotkb:Q8N3I5|uniprotkb:Q8NAI0|uniprotkb:Q9UPW1|intact:EBI-2829603|intact:EBI-358896|uniprotkb:Q8NHE2|uniprotkb:B9EGP5|uniprotkb:F8VWA6|uniprotkb:F8W1Z6|intact:EBI-10962461|ensembl:ENSP00000377250 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:mon2_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)|uniprotkb:KIAA1040(gene name synonym)|uniprotkb:SF21(gene name synonym)|uniprotkb:Protein SF21(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001265399.1|refseq:NP_001265398.1|refseq:NP_055841.2|refseq:XP_016874530.1|ensembl:ENSG00000061987(gene)|ensembl:ENST00000393630(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026829|interpro:IPR032629|interpro:IPR032691|interpro:IPR032817|mint:Q7Z3U7 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:pEkENsLrswc7Cb2WTKZfQdESrtQ9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q7RTS9 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2871106|uniprotkb:A8K5I8|uniprotkb:Q3ZTS8|uniprotkb:Q9NPU7|uniprotkb:Q6P2P5|uniprotkb:B4DKI7|uniprotkb:Q9BVE9|uniprotkb:B2RCF9|uniprotkb:Q8N2M0|ensembl:ENSP00000269445 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:dym_human(display_long)|uniprotkb:DYM(gene name)|psi-mi:DYM(display_short)|uniprotkb:Dyggve-Melchior-Clausen syndrome protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_060123.3|ensembl:ENSG00000141627(gene)|ensembl:ENST00000269445(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0060348"(bone development)|interpro:IPR019142 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:4o4oPqyjY7dKe5VV26gDM6rXIFM9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q7L8L6 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-747570|uniprotkb:Q96JN3|uniprotkb:Q9H5D1|uniprotkb:Q9H8Y3|ensembl:ENSP00000369618 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:fakd5_human(display_long)|uniprotkb:FASTKD5(gene name)|psi-mi:FASTKD5(display_short)|uniprotkb:KIAA1792(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_068598.1|ensembl:ENSG00000215251(gene)|ensembl:ENST00000380266(transcript)|go:"GO:0000963"(mitochondrial RNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:i48wNX7cmBCPpWXkXfnZhGnrse89606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q6PJG6 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-10826195|uniprotkb:C9JY24|uniprotkb:Q8IW85|uniprotkb:Q8IZ43|uniprotkb:Q8WVR8|uniprotkb:A4D200|uniprotkb:Q96IV9|ensembl:ENSP00000339637|uniprotkb:Q9H7J8|uniprotkb:Q9UFA3 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:brat1_human(display_long)|uniprotkb:BRAT1(gene name)|psi-mi:BRAT1(display_short)|uniprotkb:BAAT1(gene name synonym)|uniprotkb:C7orf27(gene name synonym)|uniprotkb:BRCA1-associated protein required for ATM activation protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000106009(gene)|ensembl:ENST00000340611(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0051646"(mitochondrion localization)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038904|mint:Q6PJG6|rcsb pdb:4IFI|refseq:NP_689956.2 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:fLa3Dz0KHxEolgfbI7cbPsqolpw9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q6P3X3 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1057046|uniprotkb:A6NKJ0|uniprotkb:Q96SS5|uniprotkb:Q9BVF1|uniprotkb:Q9NWR4|uniprotkb:Q9NXG4|ensembl:ENSP00000313953 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ttc27_human(display_long)|uniprotkb:TTC27(gene name)|psi-mi:TTC27(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001180438.1|refseq:NP_060205.3|ensembl:ENSG00000018699(gene)|ensembl:ENST00000317907(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR044244|mint:Q6P3X3 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:LvE8UTgFaNjAZEkxCnmPTr/YP+Q9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q6AI08 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-359123|uniprotkb:Q6MZX1|uniprotkb:Q6MZY2|uniprotkb:Q9H6B3|uniprotkb:Q9H6M7|uniprotkb:Q8TDM9|uniprotkb:B3KXP3|ensembl:ENSP00000184956 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:heat6_human(display_long)|uniprotkb:HEATR6(gene name)|psi-mi:HEATR6(display_short)|uniprotkb:ABC1(gene name synonym)|uniprotkb:Amplified in breast cancer protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_071353.4|ensembl:ENSG00000068097(gene)|ensembl:ENST00000184956(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025283|mint:Q6AI08 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:NGkhkRsJprf1B6Bnm6OUInkcpv49606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q5T9L3 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q5T1Q4 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-13365456|ensembl:ENSP00000353557|uniprotkb:B4DJ02|uniprotkb:E1P564|uniprotkb:Q1RMG1|uniprotkb:Q4G0U9|uniprotkb:Q4G167|uniprotkb:Q6N007 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:s35f1_human(display_long)|uniprotkb:SLC35F1(gene name)|psi-mi:SLC35F1(display_short)|uniprotkb:C6orf169(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENST00000360388(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR009262(Protein of unknown function DUF914, eukaryotic)|ensembl:ENSG00000196376(gene)|refseq:NP_001025029.2|refseq:XP_005266922.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:AbRXg565Up0TwymhhcbIf9oSxeY9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q5H8A4 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11724298|uniprotkb:B4DKC7|uniprotkb:Q2TAK5|uniprotkb:Q6UX31|uniprotkb:Q7L5Y4|uniprotkb:Q8N866|uniprotkb:Q8NCC9|uniprotkb:Q96SY9|uniprotkb:Q9BVT7|uniprotkb:Q9NXG5|ensembl:ENSP00000415203 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:pigg_human(display_long)|uniprotkb:PIGG(gene name)|psi-mi:PIGG(display_short)|uniprotkb:GPI7(gene name synonym)|uniprotkb:GPI7 homolog(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class G protein(gene name synonym)|uniprotkb:UNQ1930/PRO4405(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_060203.3|refseq:NP_001120650.1|refseq:NP_001275980.1|refseq:NP_001275981.1|refseq:NP_001275984.1|refseq:NP_001275986.1|ensembl:ENST00000310340|ensembl:ENSP00000311750|ensembl:ENSP00000372494|ensembl:ENSP00000415203|ensembl:ENST00000503111|ensembl:ENSP00000426002|ensembl:ENST00000383028|ensembl:ENSG00000174227(gene)|ensembl:ENST00000453061(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0016780"(phosphotransferase activity, for other substituted phosphate groups)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0051267"(CP2 mannose-ethanolamine phosphotransferase activity)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR037674|interpro:IPR039527|mint:Q5H8A4|reactome:R-HSA-162710 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:pyq+Yfj4SCmVo17n62cZUT2YzJo9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q5BJH7 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q53R41 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-3957005|uniprotkb:Q8N583|uniprotkb:Q8TEA9|uniprotkb:Q96JM5|uniprotkb:Q96N71|uniprotkb:Q9H6T4|ensembl:ENSP00000400513 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:fakd1_human(display_long)|uniprotkb:FASTKD1(gene name)|psi-mi:FASTKD1(display_short)|uniprotkb:KIAA1800(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_078898.3|refseq:NP_001268405.1|refseq:NP_001308975.1|refseq:NP_001308977.1|refseq:NP_001308978.1|refseq:XP_016860400.1|ensembl:ENSG00000138399(gene)|ensembl:ENST00000453153(transcript)|go:"GO:0000959"(mitochondrial RNA metabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:eizlBY2w9CXu4y4WE8R4QOUWoXA9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q15386 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1058871|uniprotkb:A4D235|uniprotkb:A6NCP3|uniprotkb:Q8TC15|uniprotkb:Q96CR4|uniprotkb:Q9UDU3|intact:EBI-1237492|ensembl:ENSP00000309198 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ube3c_human(display_long)|uniprotkb:UBE3C(gene name)|psi-mi:UBE3C(display_short)|uniprotkb:KIAA0010(gene name synonym)|uniprotkb:KIAA10(gene name synonym)|uniprotkb:HectH2(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3C(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_055486.2|ensembl:ENSG00000009335(gene)|ensembl:ENST00000348165(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000569(HECT)|interpro:IPR035983|interpro:IPR044611|rcsb pdb:6K2C|reactome:R-HSA-983168|go:"GO:0000502"(proteasome complex) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:dgGb2MVtbVnFuuUAnlX4YIT39lE9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q15043 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-6116466|uniprotkb:A6NH98|uniprotkb:B4DIW3|uniprotkb:B6EU88|uniprotkb:D3DSR4|uniprotkb:Q6ZME8|uniprotkb:Q96BB3|ensembl:ENSP00000289952|ensembl:ENSP00000370635 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:s39ae_human(display_long)|uniprotkb:SLC39A14(gene name)|psi-mi:SLC39A14(display_short)|uniprotkb:KIAA0062(gene name synonym)|uniprotkb:ZIP14(gene name synonym)|uniprotkb:LIV-1 subfamily of ZIP zinc transporter 4(gene name synonym)|uniprotkb:Solute carrier family 39 member 14(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 14(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:XP_011542780.1|refseq:NP_001121903.1|refseq:NP_001128625.1|refseq:NP_056174.2|refseq:XP_005273522.1|refseq:XP_005273523.1|refseq:XP_006716387.1|refseq:XP_016868783.1|refseq:XP_016868784.1|ensembl:ENSG00000104635(gene)|ensembl:ENST00000289952(transcript)|ensembl:ENST00000381237(transcript)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005384"(manganese ion transmembrane transporter activity)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0015086"(cadmium ion transmembrane transporter activity)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0015296"("anion:cation symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033212"(iron import into cell)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051344"(negative regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055071"(manganese ion homeostasis)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|go:"GO:0098739"(import across plasma membrane)|interpro:IPR003689(Zinc/iron permease)|mint:Q15043|reactome:R-HSA-442380 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:tpJl2FORU2if7SOPN8ZDwPvF+HM9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q14CZ7 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-10234819|uniprotkb:Q9BVD3|ensembl:ENSP00000264669 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:fakd3_human(display_long)|uniprotkb:FASTKD3(gene name)|psi-mi:FASTKD3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_076996.2|refseq:XP_006714561.1|ensembl:ENSG00000124279(gene)|ensembl:ENST00000264669(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:MhzRoSmzPBUZ43yeB5FNrvjbszo9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q13505 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1052588|uniprotkb:B1AVR9|uniprotkb:B1AVS0|uniprotkb:B2R9P4|uniprotkb:Q9BUU3|uniprotkb:A0A0A0MRK6|ensembl:ENSP00000357360 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:mtx1_human(display_long)|uniprotkb:MTX1(gene name)|psi-mi:MTX1(display_short)|uniprotkb:MTX(gene name synonym)|uniprotkb:MTXN(gene name synonym)|uniprotkb:Mitochondrial outer membrane import complex protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_002446.3|refseq:NP_942584.2|ensembl:ENSG00000173171(gene)|ensembl:ENST00000368376(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007595"(lactation)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140275"(MIB complex)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:Q13505|reactome:R-HSA-1268020|reactome:R-HSA-8949613|reactome:R-HSA-9013404 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:LoRdRoXuGOFmrPBEt324uUHgKos9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q13433 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11343415|uniprotkb:B4DR49|uniprotkb:Q96HP5|uniprotkb:Q8IXR3|uniprotkb:B4E224|ensembl:ENSP00000269187|ensembl:ENSP00000465915 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:s39a6_human(display_long)|uniprotkb:SLC39A6(gene name)|psi-mi:SLC39A6(display_short)|uniprotkb:Estrogen-regulated protein LIV-1(gene name synonym)|uniprotkb:LIV1(gene name synonym)|uniprotkb:Solute carrier family 39 member 6(gene name synonym)|uniprotkb:ZIP6(gene name synonym)|uniprotkb:Zrt- and Irt-like protein 6(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_036451.3|refseq:NP_001092876.1|refseq:XP_011524202.1|refseq:XP_011524203.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0009986"(cell surface)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|interpro:IPR003689(Zinc/iron permease)|reactome:R-HSA-442380|go:"GO:0005385"(zinc ion transmembrane transporter activity)|ensembl:ENSG00000141424(gene)|ensembl:ENST00000269187(transcript)|ensembl:ENST00000590986(transcript) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:Ab1Ra9K7xoOlr7A7j9hd5gjAw9w9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:Q13409 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-742998|ensembl:ENSP00000380308|ensembl:ENSP00000386415|uniprotkb:Q96NG7|uniprotkb:Q96S87|uniprotkb:Q9BXZ5|uniprotkb:Q9NT58|uniprotkb:Q32LY9|uniprotkb:Q53S84|uniprotkb:Q5BJF8|uniprotkb:Q7Z4X1|uniprotkb:D3DPD4|uniprotkb:D3DPD5|uniprotkb:D3DPD6|uniprotkb:B7ZA04 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:dc1i2_human(display_long)|uniprotkb:Cytoplasmic dynein intermediate chain 2(gene name synonym)|uniprotkb:Dynein intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:DYNC1I2(gene name)|psi-mi:DYNC1I2(display_short)|uniprotkb:DNCIC2(gene name synonym)|uniprotkb:DNCI2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000077380(gene)|ensembl:ENST00000397119(transcript)|ensembl:ENST00000409773(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0010970"(transport along microtubule)|go:"GO:0031982"(vesicle)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|mint:Q13409|reactome:R-HSA-380270|rcsb pdb:5JPW|reactome:R-HSA-380284|rcsb pdb:6F1T|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|rcsb pdb:6F1U|rcsb pdb:6F1Z|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|refseq:NP_001369.1|refseq:NP_001258714.1|refseq:NP_001258717.1|refseq:NP_001258718.1|refseq:NP_001258719.1|refseq:NP_001258715.1|refseq:NP_001307811.1|refseq:NP_001307812.1|refseq:NP_001307813.1|refseq:NP_001258716.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:dTj7k9h8BQ+etwfwsE2MEY2nXRM9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P98194 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-2939877|ensembl:ENSP00000395809|ensembl:ENSP00000424783|ensembl:ENSP00000427461|uniprotkb:B2RAT7|uniprotkb:O76005|uniprotkb:Q86V72|uniprotkb:Q86V73|uniprotkb:Q8N6V1|uniprotkb:Q8NCJ7|uniprotkb:B4DSW3|uniprotkb:B7Z3X9|uniprotkb:G3XAH8|uniprotkb:G8JLN9 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:at2c1_human(display_long)|uniprotkb:ATP2C1(gene name)|psi-mi:ATP2C1(display_short)|uniprotkb:KIAA1347(gene name synonym)|uniprotkb:PMR1L(gene name synonym)|uniprotkb:"ATP-dependent Ca(2+) pump PMR1"(gene name synonym)|uniprotkb:"Ca(2+)/Mn(2+)-ATPase 2C1"(gene name synonym)|uniprotkb:"Secretory pathway Ca(2+)-transporting ATPase type 1"(gene name synonym)|uniprotkb:HUSSY-28(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000017260(gene)|ensembl:ENST00000428331(transcript)|ensembl:ENST00000508532(transcript)|ensembl:ENST00000510168(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0015410"(ABC-type manganese transporter activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032468"(Golgi calcium ion homeostasis)|go:"GO:0032472"(Golgi calcium ion transport)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098629"(trans-Golgi network membrane organization)|go:"GO:0140613"(P-type manganese transporter activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006413(Calcium-transporting P-type ATPase, PMR1-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030336|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837|refseq:NP_001001485.1|refseq:NP_001001486.1|refseq:NP_001001487.1|refseq:NP_001186108.1|refseq:NP_001186109.1|refseq:NP_001186110.1|refseq:NP_001186111.1|refseq:NP_001186112.1|refseq:NP_001186113.1|refseq:NP_001186114.1|refseq:NP_055197.2|refseq:XP_016861653.1|refseq:XP_005247412.1|refseq:XP_005247413.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:jPAb8dnATDdbBvc++3El2w2Zaeg9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P61803 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1052916|uniprotkb:O08552|uniprotkb:O70364|uniprotkb:P46966|uniprotkb:P46968|uniprotkb:Q6FGA3|uniprotkb:Q96GB7|uniprotkb:D3DS25|ensembl:ENSP00000250498 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:dad1_human(display_long)|uniprotkb:Defender against cell death 1(gene name synonym)|uniprotkb:DAD1(gene name)|psi-mi:DAD1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001335.1|ensembl:ENSG00000129562(gene)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR003038(Defender against death DAD protein)|mint:P61803|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-446203|reactome:R-HSA-9694548|ensembl:ENST00000250498(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine) - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:F7W13/LSSkZUPGLSXoXTfb3i4nY9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P56589 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-594885|uniprotkb:Q6FGP5|ensembl:ENSP00000356563 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:pex3_human(display_long)|uniprotkb:Peroxisomal assembly protein PEX3(gene name synonym)|uniprotkb:PEX3(gene name)|psi-mi:PEX3(display_short)|uniprotkb:Peroxin-3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_003621.1|ensembl:ENSG00000034693(gene)|ensembl:ENST00000367591(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032994"(protein-lipid complex)|go:"GO:0045046"(protein import into peroxisome membrane)|interpro:IPR006966(Peroxin-3)|rcsb pdb:3AJB|rcsb pdb:3MK4|reactome:R-HSA-1369062|reactome:R-HSA-9603798 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:zB+V5tVREEww2DOugIl6YVsUqdM9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P49768 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-297277|ensembl:ENSP00000326366|uniprotkb:O95465|uniprotkb:Q14762|uniprotkb:Q15719|uniprotkb:Q15720|uniprotkb:Q96P33|uniprotkb:Q9UIF0|uniprotkb:B2R6D3 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:psn1_human(display_long)|uniprotkb:PSEN1(gene name)|psi-mi:PSEN1(display_short)|uniprotkb:AD3(gene name synonym)|uniprotkb:PS1(gene name synonym)|uniprotkb:PSNL1(gene name synonym)|uniprotkb:Protein S182(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENST00000324501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000776"(kinetochore)|go:"GO:0001568"(blood vessel development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001764"(neuron migration)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001947"(heart looping)|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0003407"(neural retina development)|go:"GO:0004175"(endopeptidase activity)|ensembl:ENSG00000080815(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006816"(calcium ion transport)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050820"(positive regulation of coagulation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051563"(smooth endoplasmic reticulum calcium ion homeostasis)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904797"(negative regulation of core promoter binding)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001108(Peptidase A22A, presenilin)|interpro:IPR002031(Peptidase A22A, presenilin 1)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR042524|mint:P49768|rcsb pdb:2KR6|rcsb pdb:4UIS|rcsb pdb:5A63|rcsb pdb:5FN2|rcsb pdb:5FN3|rcsb pdb:5FN4|rcsb pdb:5FN5|rcsb pdb:6IDF|rcsb pdb:6IYC|rcsb pdb:6LQG|rcsb pdb:6LR4|rcsb pdb:7C9I|rcsb pdb:7D8X|reactome:R-HSA-1251985|reactome:R-HSA-1474228|reactome:R-HSA-193692|reactome:R-HSA-205043|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3928665|reactome:R-HSA-6798695|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-9017802|go:"GO:0015871"(choline transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0021549"(cerebellum development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021870"(Cajal-Retzius cell differentiation)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0015031"(protein transport)|go:"GO:0030018"(Z disc)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048666"(neuron development)|go:"GO:0048705"(skeletal system morphogenesis)|refseq:NP_000012.1|refseq:NP_015557.2|refseq:XP_011535273.1|refseq:XP_011535274.1|refseq:XP_011535275.1|refseq:XP_011535276.1|refseq:XP_005267921.1|refseq:XP_005267923.1|dip:DIP-1134N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:KJwrVRHoYA67u579QC5EZ0Owjoc9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P43003 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-359038|uniprotkb:B2R5T3|uniprotkb:Q4JCQ8|ensembl:ENSP00000265113|ensembl:ENSP00000371343|ensembl:ENSP00000505057|ensembl:ENSP00000505238|ensembl:ENSP00000506585 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:eaa1_human(display_long)|uniprotkb:SLC1A3(gene name)|psi-mi:SLC1A3(display_short)|uniprotkb:EAAT1(gene name synonym)|uniprotkb:GLAST1(gene name synonym)|uniprotkb:GLAST(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 1(gene name synonym)|uniprotkb:Solute carrier family 1 member 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_004163.3|refseq:NP_001160167.1|refseq:XP_005248399.1|refseq:NP_001276869.1|ensembl:ENSG00000079215(gene)|ensembl:ENST00000265113(transcript)|ensembl:ENST00000381918(transcript)|ensembl:ENST00000679983(transcript)|ensembl:ENST00000679992(transcript)|ensembl:ENST00000680318(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0021545"(cranial nerve development)|go:"GO:0031223"(auditory behavior)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051938"(L-glutamate import)|go:"GO:0070633"(transepithelial transport)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098796"(membrane protein complex)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1902476"(chloride transmembrane transport)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|reactome:R-HSA-210455|reactome:R-HSA-210500|reactome:R-HSA-425393|reactome:R-HSA-5619062 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:z0yfNM2Y4OFgtmwgrVEp8KGJvms9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P40763 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N - - crc64:6C00632211C8012D figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P38435 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-10963113|ensembl:ENSP00000233838|uniprotkb:B4DMC5|uniprotkb:E9PEE1|uniprotkb:Q6GU45|uniprotkb:Q14415 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:vkgc_human(display_long)|uniprotkb:GGCX(gene name)|psi-mi:GGCX(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:Gamma-glutamyl carboxylase(gene name synonym)|uniprotkb:Peptidyl-glutamate 4-carboxylase(gene name synonym)|uniprotkb:Vitamin K gamma glutamyl carboxylase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_000812.2|refseq:NP_001135741.1|ensembl:ENSG00000115486(gene)|ensembl:ENST00000233838(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007596"(blood coagulation)|go:"GO:0008488"(gamma-glutamyl carboxylase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0019842"(vitamin binding)|interpro:IPR007782(Vitamin K-dependent gamma-carboxylase)|interpro:IPR011020(HTTM)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|mint:P38435|reactome:R-HSA-159740|reactome:R-HSA-9673240 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:icDLv1KyH9HC3h9enCp9S/nXPmM9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P35670 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11668501|uniprotkb:Q16318|uniprotkb:Q16319|uniprotkb:Q4U3V3|uniprotkb:Q59FJ9|uniprotkb:Q5T7X7|ensembl:ENSP00000242839 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:atp7b_human(display_long)|uniprotkb:ATP7B(gene name)|psi-mi:ATP7B(display_short)|uniprotkb:PWD(gene name synonym)|uniprotkb:WC1(gene name synonym)|uniprotkb:WND(gene name synonym)|uniprotkb:Copper pump 2(gene name synonym)|uniprotkb:Wilson disease-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_000044.2|refseq:NP_001230111.1|refseq:XP_005266487.1|refseq:NP_001317507.1|refseq:NP_001317508.1|ensembl:ENST00000242839(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006825"(copper ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0015677"(copper ion import)|go:"GO:0016020"(membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034220"(ion transmembrane transport)|ensembl:ENSG00000123191(gene)|go:"GO:0043682"(P-type divalent copper transporter activity)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0060003"(copper ion export)|go:"GO:0140581"(P-type monovalent copper transporter activity)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR006122(Copper ion-binding)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR017969|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR027256|interpro:IPR036163|interpro:IPR036412|interpro:IPR044492|rcsb pdb:2ARF|rcsb pdb:2EW9|go:"GO:0046688"(response to copper ion)|rcsb pdb:2KOY|rcsb pdb:2LQB|rcsb pdb:2N7Y|rcsb pdb:2ROP|rcsb pdb:6A71|rcsb pdb:6A72|reactome:R-HSA-936837 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:wC7xp3y5M7M41Wzpmcy70jQqK4w9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P33527 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-3911547|uniprotkb:O14819|uniprotkb:Q9UQ99|uniprotkb:P78419|uniprotkb:A3RJX2|uniprotkb:Q59GI9|uniprotkb:O43333|uniprotkb:Q9UQ97|uniprotkb:Q9UQA0|uniprotkb:C9JPJ4|ensembl:ENSP00000382342|ensembl:ENSP00000483316 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:mrp1_human(display_long)|uniprotkb:ABCC1(gene name)|psi-mi:ABCC1(display_short)|uniprotkb:MRP(gene name synonym)|uniprotkb:MRP1(gene name synonym)|uniprotkb:ATP-binding cassette sub-family C member 1(gene name synonym)|uniprotkb:"Leukotriene C(4) transporter"(gene name synonym)|uniprotkb:Glutathione-S-conjugate-translocating ATPase ABCC1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_004987.2|ensembl:ENSG00000103222(gene)|ensembl:ENSG00000278183(gene)|ensembl:ENST00000399410(transcript)|ensembl:ENST00000621144(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015420"(ABC-type vitamin B12 transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0034040"(ATPase-coupled lipid transmembrane transporter activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0034775"(glutathione transmembrane transport)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070633"(transepithelial transport)|go:"GO:0071716"(leukotriene transport)|go:"GO:0099039"(sphingolipid translocation)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0140359"(ABC-type transporter activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905039"(carboxylic acid transmembrane transport)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005292("Multi drug resistance-associated protein (MRP)")|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P33527|rcsb pdb:2CBZ|rcsb pdb:4C3Z|reactome:R-HSA-196741|reactome:R-HSA-2142691|reactome:R-HSA-382556|reactome:R-HSA-9707564|reactome:R-HSA-189483 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:XGzXibUwQjwbAsg7ueuXS9YxUVc9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P24390 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1043076|uniprotkb:B2R6N4|ensembl:ENSP00000329471|uniprotkb:Q54A39|uniprotkb:Q8NBW7 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:erd21_human(display_long)|uniprotkb:KDELR1(gene name)|psi-mi:KDELR1(display_short)|uniprotkb:ERD2.1(gene name synonym)|uniprotkb:KDEL endoplasmic reticulum protein retention receptor 1(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM23(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000105438(gene)|ensembl:ENST00000330720(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005046"(KDEL sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046923"(ER retention sequence binding)|go:"GO:0070231"(T cell apoptotic process)|interpro:IPR000133(ER lumen protein retaining receptor)|mint:P24390|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_006792.1|dip:DIP-48668N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:V+4Hb765BqjFuT1/ewZWs9gNQ/M9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P23634 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P20020 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-5279998|uniprotkb:Q12992|uniprotkb:Q12993|uniprotkb:Q13819|uniprotkb:Q13820|uniprotkb:Q13821|uniprotkb:Q16504|uniprotkb:Q93082|ensembl:ENSP00000261173|ensembl:ENSP00000392043 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:at2b1_human(display_long)|uniprotkb:ATP2B1(gene name)|psi-mi:ATP2B1(display_short)|uniprotkb:PMCA1(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:XP_011536709.1|refseq:NP_001001323.1|refseq:NP_001673.2|refseq:XP_016874847.1|reactome:R-HSA-9662360|ensembl:ENSG00000070961(gene)|ensembl:ENST00000261173(transcript)|ensembl:ENST00000428670(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030320|interpro:IPR036412|interpro:IPR044492|mint:P20020|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|rcsb pdb:6A69|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:kCpUNLYDF38hciXj32D8rXbXULg9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P07384 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1542113|uniprotkb:Q2TTR0|uniprotkb:Q6DHV4|ensembl:ENSP00000279247|ensembl:ENSP00000431686|ensembl:ENSP00000431984|ensembl:ENSP00000434176|ensembl:ENSP00000435272 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:can1_human(display_long)|uniprotkb:CAPN1(gene name)|psi-mi:CAPN1(display_short)|uniprotkb:CANPL1(gene name synonym)|uniprotkb:Calpain-1 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 1(gene name synonym)|uniprotkb:Calpain mu-type(gene name synonym)|uniprotkb:Micromolar-calpain(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 30 protein(gene name synonym)|uniprotkb:PIG30(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:XP_006718761.1|refseq:NP_001185797.1|refseq:NP_001185798.1|refseq:NP_005177.2|refseq:XP_011543594.1|ensembl:ENSG00000014216(gene)|ensembl:ENST00000279247(transcript)|ensembl:ENST00000524773(transcript)|ensembl:ENST00000527323(transcript)|ensembl:ENST00000533129(transcript)|ensembl:ENST00000533820(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060056"(mammary gland involution)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097264"(self proteolysis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029643|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|mint:P07384|rcsb pdb:1ZCM|rcsb pdb:2ARY|reactome:R-HSA-1474228|reactome:R-HSA-6798695|reactome:R-HSA-6809371|reactome:R-HSA-8862803 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:hLf5vu04E7/yonXBb9VIZThbcxk9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:P05026 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O95864 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-11337838|uniprotkb:A8K2M6|uniprotkb:Q6MZQ7|uniprotkb:Q9H3G3|uniprotkb:Q9Y3X4|uniprotkb:B7Z634|uniprotkb:Q96SV8|uniprotkb:Q96H07|ensembl:ENSP00000278840 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:fads2_human(display_long)|uniprotkb:Fatty acid desaturase 2(gene name synonym)|uniprotkb:FADS2(gene name)|psi-mi:FADS2(display_short)|uniprotkb:"Delta(6) fatty acid desaturase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001268430.1|refseq:NP_001268431.1|refseq:NP_004256.1|ensembl:ENSG00000134824(gene)|ensembl:ENST00000278840(transcript)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016213"(linoleoyl-CoA desaturase activity)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043651"(linoleic acid metabolic process)|interpro:IPR001199(Cytochrome b5)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR012171(Fatty acid/sphingolipid desaturase)|interpro:IPR036400|mint:O95864|reactome:R-HSA-2046105|reactome:R-HSA-2046106 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:xyJ9VBTFjemwT3LQSM4bdikd4Zk9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O95674 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-3913685|uniprotkb:Q5TDY5|uniprotkb:Q5TDY3|uniprotkb:Q5TDY2|uniprotkb:Q9NTT2|uniprotkb:Q9BYK5|uniprotkb:Q5TDY4|uniprotkb:D3DW04|uniprotkb:B2RDC6|ensembl:ENSP00000419879 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:cds2_human(display_long)|uniprotkb:CDS2(gene name)|psi-mi:CDS2(display_short)|uniprotkb:CDP-DAG synthase 2(gene name synonym)|uniprotkb:CDP-DG synthase 2(gene name synonym)|uniprotkb:CDP-diacylglycerol synthase 2(gene name synonym)|uniprotkb:CDP-diglyceride pyrophosphorylase 2(gene name synonym)|uniprotkb:CDP-diglyceride synthase 2(gene name synonym)|uniprotkb:"CTP:phosphatidate cytidylyltransferase 2"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_003809.1|ensembl:ENSG00000101290(gene)|ensembl:ENST00000460006(transcript)|go:"GO:0004605"(phosphatidate cytidylyltransferase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR000374(Phosphatidate cytidylyltransferase)|interpro:IPR016720(Phosphatidate cytidylyltransferase, eukaryota)|mint:O95674|reactome:R-HSA-1483148 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:tCRLIDMiesBx7QPKIycdX3Igz589606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O94829 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-747310|uniprotkb:Q7LC04|uniprotkb:Q96HS3|uniprotkb:Q9H8N3|uniprotkb:Q9UFR1|uniprotkb:Q5T4X3|uniprotkb:D3DPY4|ensembl:ENSP00000361418 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ipo13_human(display_long)|uniprotkb:Ran-binding protein 13(gene name synonym)|uniprotkb:Karyopherin-13(gene name synonym)|uniprotkb:IPO13(gene name)|psi-mi:IPO13(display_short)|uniprotkb:KIAA0724(gene name synonym)|uniprotkb:RANBP13(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_055467.3|ensembl:ENSG00000117408(gene)|ensembl:ENST00000372343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040520|interpro:IPR040709|interpro:IPR040944|rcsb pdb:2X19|rcsb pdb:2XWU|rcsb pdb:3ZJY - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:HC5CjdyfnwoVeE9JNHgicwFybWc9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O94822 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1044684|uniprotkb:Q9H8M4|uniprotkb:Q9NUY5|uniprotkb:Q9P0E9|uniprotkb:A7E2D0|uniprotkb:B2RTS0|uniprotkb:C9J7U3|uniprotkb:Q05C47|uniprotkb:A6NL41|uniprotkb:J3KPL4|intact:EBI-11051127|ensembl:ENSP00000354977|ensembl:ENSP00000373846 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ltn1_human(display_long)|uniprotkb:LTN1(gene name)|psi-mi:LTN1(display_short)|uniprotkb:ZNF294(gene name synonym)|uniprotkb:C21orf10(gene name synonym)|uniprotkb:C21orf98(gene name synonym)|uniprotkb:KIAA0714(gene name synonym)|uniprotkb:HSPC087(orf name)|uniprotkb:Zinc finger protein 294(gene name synonym)|uniprotkb:RNF160(gene name synonym)|uniprotkb:RING finger protein 160(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase listerin(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_056380.2|refseq:NP_001307695.1|ensembl:ENSG00000198862(gene)|ensembl:ENST00000361371(transcript)|ensembl:ENST00000389194(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1990112"(RQC complex)|go:"GO:1990116"(ribosome-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039795|interpro:IPR039804|rcsb pdb:3J92|reactome:R-HSA-983168 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:ysR3JH2PPNrc1EwOpusyQoGrYFw9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O75027 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1236950|uniprotkb:O75345|uniprotkb:Q5VWY7|uniprotkb:Q5VWY8|uniprotkb:Q9BRE1|uniprotkb:Q9UND1|uniprotkb:Q9UP01|uniprotkb:G3XAC4|ensembl:ENSP00000362492 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:abcb7_human(display_long)|uniprotkb:ABCB7(gene name)|psi-mi:ABCB7(display_short)|uniprotkb:ABC7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001258626.1|ensembl:ENSG00000131269(gene)|ensembl:ENST00000373394(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:O75027|reactome:R-HSA-1369007|reactome:R-HSA-2564830|refseq:NP_004290.2|refseq:NP_001258625.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:nsOzSS/enZTkOfd1nRlk8Wv4KRM9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O60779 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-3941998|uniprotkb:Q8WV87|uniprotkb:Q9UBL7|uniprotkb:Q9UN31|uniprotkb:Q9UN43|uniprotkb:B2R9H0|uniprotkb:Q9UKJ2|uniprotkb:B4E1X4|ensembl:ENSP00000236137 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:s19a2_human(display_long)|uniprotkb:SLC19A2(gene name)|psi-mi:SLC19A2(display_short)|uniprotkb:THT1(gene name synonym)|uniprotkb:TRMA(gene name synonym)|uniprotkb:Solute carrier family 19 member 2(gene name synonym)|uniprotkb:Thiamine carrier 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 interpro:IPR002666(Reduced folate carrier)|interpro:IPR028338|ensembl:ENSG00000117479(gene)|interpro:IPR036259|mint:O60779|ensembl:ENST00000236137(transcript)|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-196819|go:"GO:0008517"(folic acid transmembrane transporter activity)|go:"GO:0015234"(thiamine transmembrane transporter activity)|go:"GO:0015888"(thiamine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042723"(thiamine-containing compound metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071934"(thiamine transmembrane transport)|refseq:NP_008927.1|refseq:NP_001306596.1 - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:jaxPhDzyD6VTkLBvxtw/nCixzAE9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O43156 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1055680|uniprotkb:Q5JX67|uniprotkb:Q96A38|uniprotkb:Q9BR47|uniprotkb:Q9H4K0|uniprotkb:D6W4K3|ensembl:ENSP00000362546|ensembl:ENSP00000362547|ensembl:ENSP00000407270 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:tti1_human(display_long)|uniprotkb:TTI1(gene name)|psi-mi:TTI1(display_short)|uniprotkb:KIAA0406(gene name synonym)|uniprotkb:SMG10(gene name synonym)|uniprotkb:Protein SMG10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001290386.1|refseq:NP_055472.1|ensembl:ENSG00000101407(gene)|ensembl:ENST00000373447(transcript)|ensembl:ENST00000373448(transcript)|ensembl:ENST00000449821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0070209"(ASTRA complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016441(Uncharacterised conserved protein UCP005250)|dip:DIP-50660N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:64WoojA64oXXnupzAKEbytnly1s9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O15431 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-15571835|ensembl:ENSP00000363329|uniprotkb:A8K8Z6|uniprotkb:Q53GR5|uniprotkb:Q5T1M4 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:copt1_human(display_long)|uniprotkb:SLC31A1(gene name)|psi-mi:SLC31A1(display_short)|uniprotkb:COPT1(gene name synonym)|uniprotkb:CTR1(gene name synonym)|uniprotkb:Copper transporter 1(gene name synonym)|uniprotkb:Solute carrier family 31 member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 ensembl:ENSG00000136868(gene)|ensembl:ENST00000374212(transcript)|go:"GO:0005375"(copper ion transmembrane transporter activity)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006825"(copper ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0055037"(recycling endosome)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0098705"(copper ion import across plasma membrane)|interpro:IPR007274(Ctr copper transporter)|rcsb pdb:2LS2|rcsb pdb:2LS3|rcsb pdb:2LS4|reactome:R-HSA-425410|refseq:NP_001850.1|dip:DIP-48727N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:4XscGl2f2dNUi+R8IGd5/TxCbs49606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O15397 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59596 uniprotkb:O15321 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-1390491|uniprotkb:Q96FI8|uniprotkb:D3DS65|uniprotkb:Q86SZ6|intact:EBI-28976916|ensembl:ENSP00000261789|ensembl:ENSP00000494320 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:tm9s1_human(display_long)|uniprotkb:TM9SF1(gene name)|psi-mi:TM9SF1(display_short)|uniprotkb:MP70 protein family member(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376514|imex:IM-28441-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 refseq:NP_001014842.1|refseq:NP_006396.2|ensembl:ENSP00000494320|ensembl:ENSP00000261789|ensembl:ENST00000396854|ensembl:ENSP00000380063|ensembl:ENST00000646500|ensembl:ENSP00000494851|refseq:NP_001275935.1|ensembl:ENSG00000100926(gene)|ensembl:ENSG00000285465(gene)|ensembl:ENST00000261789(transcript)|ensembl:ENST00000646762(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)") - - - figure legend:Table 2, no 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:y4t2+OC3qVXBRLxyH65ywVx8Ja09606 rigid:VHz8PKNXdnF+EpEskCN5c2j2Fpo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q9Y3U8 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q9HCE1 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:P68400 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:P11940 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:O76021 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q9UN86 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|ensembl:ENSP00000352738|ensembl:ENSP00000379069|ensembl:ENSP00000503228|ensembl:ENSP00000503239|ensembl:ENSP00000503355|ensembl:ENSP00000503669|ensembl:ENSP00000503911|ensembl:ENSP00000503943|ensembl:ENSP00000504101|ensembl:ENSP00000504159|ensembl:ENSP00000504316|ensembl:ENSP00000504361|ensembl:ENSP00000504371|ensembl:ENSP00000504496|ensembl:ENSP00000504523|ensembl:ENSP00000504585|ensembl:ENSP00000504698|ensembl:ENSP00000503504|uniprotkb:A8K6X1 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|ensembl:ENSG00000138757(gene)|ensembl:ENST00000677620(transcript)|ensembl:ENST00000678062(transcript)|ensembl:ENST00000678100(transcript)|ensembl:ENST00000678123(transcript)|ensembl:ENST00000678265(transcript)|ensembl:ENST00000678578(transcript)|ensembl:ENST00000678798(transcript)|ensembl:ENST00000678971(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|ensembl:ENST00000359707(transcript)|ensembl:ENST00000395719(transcript)|ensembl:ENST00000676584(transcript)|ensembl:ENST00000676974(transcript)|ensembl:ENST00000677162(transcript)|ensembl:ENST00000677171(transcript)|ensembl:ENST00000677201(transcript)|ensembl:ENST00000677333(transcript)|ensembl:ENST00000677566(transcript)|ensembl:ENST00000677606(transcript)|refseq:XP_011530743.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q9BQ75 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-395649|uniprotkb:A8K5S7|ensembl:ENSP00000410396|uniprotkb:B4DUM1|uniprotkb:E9PHS3|intact:EBI-11119778 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:cms1_human(display_long)|uniprotkb:CMSS1(gene name)|psi-mi:CMSS1(display_short)|uniprotkb:C3orf26(gene name synonym)|uniprotkb:Cms1 ribosomal small subunit homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_115735.2|refseq:NP_001161396.1|ensembl:ENSG00000184220(gene)|ensembl:ENST00000421999(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR027417|interpro:IPR032704|mint:Q9BQ75 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:y335t6JRY1YTvmgzS1tQJVJGPuI9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q8TAD8 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-749336|uniprotkb:Q96SP9|uniprotkb:Q9H9T7|intact:EBI-1046254|ensembl:ENSP00000296215 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:snip1_human(display_long)|uniprotkb:SNIP1(gene name)|psi-mi:SNIP1(display_short)|uniprotkb:FHA domain-containing protein SNIP1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_078976.2|ensembl:ENSG00000163877(gene)|ensembl:ENST00000296215(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-38956N|mint:Q8TAD8|rcsb pdb:5Z56|rcsb pdb:5Z57|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5Z58|rcsb pdb:6FF7|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:2UWnTY01RhPuUx3PepGug23l11U9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q8NCA5 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-1210765|uniprotkb:B2RNA2|uniprotkb:Q9Y3Y6|intact:EBI-10970131|ensembl:ENSP00000238823 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:fa98a_human(display_long)|uniprotkb:FAM98A(gene name)|psi-mi:FAM98A(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_056290.3|go:"GO:0032418"(lysosome localization)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR018797|mint:Q8NCA5|ensembl:ENSG00000119812(gene)|ensembl:ENST00000238823(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006479"(protein methylation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression) - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:MEsSX6iNk+0s/sLuUawu0GR9bW89606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q86U42 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q6PKG0 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q13310 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:Q13283 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:P67870 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:P19784 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:P16989 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:O75683 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-2691252|uniprotkb:Q9UK24|uniprotkb:Q9BTZ5|uniprotkb:Q5T8U1|uniprotkb:Q9BRK9|ensembl:ENSP00000361092|ensembl:ENSP00000485909 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:surf6_human(display_long)|uniprotkb:SURF-6(gene name synonym)|uniprotkb:SURF6(gene name)|psi-mi:SURF6(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_006744.2|refseq:NP_001265871.1|ensembl:ENSG00000148296(gene)|ensembl:ENSG00000281309(gene)|ensembl:ENST00000372022(transcript)|ensembl:ENST00000629980(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007019(Surfeit locus 6)|interpro:IPR029190 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:1Yzf0+p31xuzJXSoaiz9THfjF0c9606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59595 uniprotkb:O43818 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-2115327|uniprotkb:Q8IZ30|uniprotkb:B2R996|ensembl:ENSP00000232888 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:u3ip2_human(display_long)|uniprotkb:RRP9(gene name)|psi-mi:RRP9(display_short)|uniprotkb:RNU3IP2(gene name synonym)|uniprotkb:U355K(gene name synonym)|uniprotkb:U3 small nucleolar ribonucleoprotein-associated 55 kDa protein(gene name synonym)|uniprotkb:RRP9 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376911|imex:IM-28441-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 refseq:NP_004695.1|ensembl:ENSG00000114767(gene)|ensembl:ENST00000232888(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR039241|rcsb pdb:4J0W|rcsb pdb:4JXM|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Table 2, no 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:AxnPDovGXO2JPghV7c6ztiV1/z89606 rigid:bu7lBJsUobqMI3Tr0u9fhV0Iwi0 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037309 uniprotkb:P49643 intact:EBI-25475797 intact:EBI-850004|uniprotkb:Q53FJ8|uniprotkb:Q6P1Q7|uniprotkb:Q8WVL2|uniprotkb:Q9H413|ensembl:ENSP00000484105 psi-mi:p0c6x7-pro_0000037309(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pri2_human(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:PRIM2(gene name)|psi-mi:PRIM2(display_short)|uniprotkb:PRIM2A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376937|imex:IM-28441-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001269416.1|refseq:NP_001269417.1|refseq:NP_000938.2|dip:DIP-36438N|ensembl:ENSG00000146143(gene)|ensembl:ENST00000615550(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|mint:P49643|rcsb pdb:3L9Q|rcsb pdb:3Q36|rcsb pdb:4BPU|rcsb pdb:4BPW|rcsb pdb:4BPX|rcsb pdb:4RR2|rcsb pdb:5DQO|rcsb pdb:5EXR|rcsb pdb:5F0Q|rcsb pdb:5F0S|rcsb pdb:5I7M|rcsb pdb:6DHW|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-9710421 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:qbwEpGmE3J035KnL6QbEZ/HRJAw694009 rogid:WL5i+CvK52C93/3X4a3MFQvD0JQ9606 rigid:A8sdjGZPrvxC7J5OQk+/vBhlkck false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037309 uniprotkb:P49642 intact:EBI-25475797 intact:EBI-726050|ensembl:ENSP00000350491 psi-mi:p0c6x7-pro_0000037309(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pri1_human(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:PRIM1(gene name)|psi-mi:PRIM1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376937|imex:IM-28441-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000198056(gene)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|refseq:NP_000937.1|rcsb pdb:4BPU|rcsb pdb:4BPW|ensembl:ENST00000338193(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0032553"(ribonucleotide binding)|rcsb pdb:4BPX|rcsb pdb:4LIK|interpro:IPR002755(DNA primase, small subunit)|rcsb pdb:4LIL|rcsb pdb:4MHQ|rcsb pdb:4RR2|rcsb pdb:5EXR|rcsb pdb:6R4S|rcsb pdb:6R4T|rcsb pdb:6R4U|rcsb pdb:6R5D|rcsb pdb:6R5E|rcsb pdb:6RB4|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-9710421 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:qbwEpGmE3J035KnL6QbEZ/HRJAw694009 rogid:bgNj0hjvHPliBXVfkZmg7v0N/uw9606 rigid:A8sdjGZPrvxC7J5OQk+/vBhlkck false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037309 uniprotkb:P09884 intact:EBI-25475797 intact:EBI-850026|uniprotkb:Q86UQ7|intact:EBI-28966824|ensembl:ENSP00000368349 psi-mi:p0c6x7-pro_0000037309(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dpola_human(display_long)|uniprotkb:POLA1(gene name)|psi-mi:POLA1(display_short)|uniprotkb:POLA(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376937|imex:IM-28441-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSP00000368349|refseq:NP_058633.2|ensembl:ENSG00000101868(gene)|ensembl:ENST00000379059(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|mint:P09884|rcsb pdb:1K0P|rcsb pdb:1K18|rcsb pdb:1N5G|rcsb pdb:4Q5V|rcsb pdb:4QCL|rcsb pdb:4Y97|rcsb pdb:5EXR|rcsb pdb:5IUD|rcsb pdb:6AS7|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-9710421 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:qbwEpGmE3J035KnL6QbEZ/HRJAw694009 rogid:X/oe9TEoaNUf5UPtWEXunsFtRZg9606 rigid:A8sdjGZPrvxC7J5OQk+/vBhlkck false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037309 uniprotkb:Q14181 intact:EBI-25475797 intact:EBI-712752|ensembl:ENSP00000265465|uniprotkb:Q9BPV3|uniprotkb:B4DNB4 psi-mi:p0c6x7-pro_0000037309(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dpoa2_human(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:POLA2(gene name)|psi-mi:POLA2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376937|imex:IM-28441-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) reactome:R-HSA-69183|reactome:R-HSA-69166|reactome:R-HSA-9710421|ensembl:ENSG00000014138(gene)|ensembl:ENST00000265465(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|rcsb pdb:2KEB|rcsb pdb:4E2I|rcsb pdb:4Y97|rcsb pdb:5EXR|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|refseq:NP_002680.2 - chain-seq-start:1|chain-seq-end:180 - figure legend:Table 2, no 4|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:qbwEpGmE3J035KnL6QbEZ/HRJAw694009 rogid:cPvK8qerkbSbnl1+TAIlBqTuEFU9606 rigid:A8sdjGZPrvxC7J5OQk+/vBhlkck false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037317 uniprotkb:Q969X5 intact:EBI-25487277 intact:EBI-781527|uniprotkb:Q9H0L0|uniprotkb:Q9H2J2|uniprotkb:Q9ULN9|ensembl:ENSP00000377374 psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ergi1_human(display_long)|uniprotkb:ER-Golgi intermediate compartment 32 kDa protein(gene name synonym)|uniprotkb:ERGIC1(gene name)|psi-mi:ERGIC1(display_short)|uniprotkb:KIAA1181(gene name synonym)|uniprotkb:HT034(orf name)|uniprotkb:ERGIC32(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376953|imex:IM-28441-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:XP_006714955.1|refseq:NP_001026881.1|ensembl:ENSG00000113719(gene)|ensembl:ENST00000393784(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542 - chain-seq-start:4231|chain-seq-end:4369 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009 rogid:UbuPGmvwVwrwg/LT5oAn9pLs5Hw9606 rigid:ruMYMn40M+4kzO6WNPfQCpqyuwI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037317 uniprotkb:Q6Q0C0 intact:EBI-25487277 intact:EBI-307556|uniprotkb:Q9H073|ensembl:ENSP00000318944 psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:traf7_human(display_long)|uniprotkb:TRAF7(gene name)|psi-mi:TRAF7(display_short)|uniprotkb:TNF receptor-associated factor 7(gene name synonym)|uniprotkb:RING finger and WD repeat-containing protein 1(gene name synonym)|uniprotkb:RING finger protein 119(gene name synonym)|uniprotkb:RFWD1(gene name synonym)|uniprotkb:RNF119(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376953|imex:IM-28441-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_115647.2|ensembl:ENSG00000131653(gene)|ensembl:ENST00000326181(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001680(WD40 repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017907|interpro:IPR019775|interpro:IPR020472|interpro:IPR027370|interpro:IPR036322|mint:Q6Q0C0|reactome:R-HSA-983168 - chain-seq-start:4231|chain-seq-end:4369 - figure legend:Table 2, no 5|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009 rogid:46dtsS1OairncB0fnINSW1aY2789606 rigid:ruMYMn40M+4kzO6WNPfQCpqyuwI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6U8-PRO_0000338265 uniprotkb:Q9C0D3 intact:EBI-25492625 intact:EBI-1811414|uniprotkb:Q8N2X3|uniprotkb:Q9H8L8|ensembl:ENSP00000294353 psi-mi:p0c6u8-pro_0000338265(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym)|uniprotkb:1a(orf name) psi-mi:zy11b_human(display_long)|uniprotkb:ZYG11B(gene name)|psi-mi:ZYG11B(display_short)|uniprotkb:KIAA1730(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376963|imex:IM-28441-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-15810860(chain-parent) refseq:NP_078922.1|ensembl:ENSG00000162378(gene)|ensembl:ENST00000294353(transcript)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|interpro:IPR040367|mint:Q9C0D3 - chain-seq-start:4370|chain-seq-end:4382 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:W4PafFcIlQyBvA5xTGcg9b1kh88694009 rogid:PL/P806AUcYTlvB6/2VS/UxLUYg9606 rigid:QbQVSjAzK7+khqnVaszi2HGdmIE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6U8-PRO_0000338265 uniprotkb:Q92624 intact:EBI-25492625 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:p0c6u8-pro_0000338265(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym)|uniprotkb:1a(orf name) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376963|imex:IM-28441-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-15810860(chain-parent) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - chain-seq-start:4370|chain-seq-end:4382 - figure legend:Table 2, no 6|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:W4PafFcIlQyBvA5xTGcg9b1kh88694009 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rigid:QbQVSjAzK7+khqnVaszi2HGdmIE false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:O15078 intact:EBI-25487684 intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q9HCJ0 intact:EBI-25487684 intact:EBI-6507625|uniprotkb:Q86UE5|uniprotkb:Q8N3D8|uniprotkb:Q96MU9|uniprotkb:G3XAB8|ensembl:ENSP00000301624|ensembl:ENSP00000468647 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tnr6c_human(display_long)|uniprotkb:TNRC6C(gene name)|psi-mi:TNRC6C(display_short)|uniprotkb:KIAA1582(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001136112.1|refseq:NP_061869.2|ensembl:ENSG00000078687(gene)|ensembl:ENST00000301624(transcript)|ensembl:ENST00000588061(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033499|interpro:IPR034927|interpro:IPR035979|interpro:IPR041917|rcsb pdb:2DKL|rcsb pdb:2X04|rcsb pdb:3KTP|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|dip:DIP-48569N - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:OZUDlEQ+h+8y51DpPQfEGB7tfx89606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q9HAU0 intact:EBI-25487684 intact:EBI-945934|uniprotkb:Q86ST7|uniprotkb:A0JP03|uniprotkb:Q8N3K6|uniprotkb:Q96DY9|uniprotkb:Q9BVR4|uniprotkb:Q9C0H7|uniprotkb:Q9H924|uniprotkb:Q9NVK8|uniprotkb:B4DGS1|uniprotkb:F5H0I0|uniprotkb:E9PHQ3|uniprotkb:Q6NSF8|ensembl:ENSP00000299275 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pkha5_human(display_long)|uniprotkb:PLEKHA5(gene name)|psi-mi:PLEKHA5(display_short)|uniprotkb:KIAA1686(gene name synonym)|uniprotkb:PEPP2(gene name synonym)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSP00000299275|ensembl:ENST00000424268|ensembl:ENSP00000400411|ensembl:ENST00000429027|ensembl:ENSP00000404296|ensembl:ENST00000538714|ensembl:ENSP00000439673|ensembl:ENST00000540972|ensembl:ENSP00000439396|refseq:NP_001137293.2|refseq:NP_061885.2|refseq:NP_001177789.2|refseq:NP_001243399.1|refseq:NP_001243716.1|refseq:XP_005253457.1|refseq:XP_016874992.1|refseq:XP_011519019.1|ensembl:ENSG00000052126(gene)|ensembl:ENST00000299275(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0061458"(reproductive system development)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|mint:Q9HAU0|rcsb pdb:2DKP|reactome:R-HSA-1660499 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:22W2zdIwTLw4nNRh0dHasYDCLK49606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q9H2H8 intact:EBI-25487684 intact:EBI-751051|uniprotkb:Q86WF9|uniprotkb:Q96IA9|uniprotkb:Q9BXZ1|ensembl:ENSP00000376107 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ppil3_human(display_long)|uniprotkb:Cyclophilin-like protein PPIL3(gene name synonym)|uniprotkb:Cyclophilin J(gene name synonym)|uniprotkb:PPIL3(gene name)|psi-mi:PPIL3(display_short)|uniprotkb:Rotamase PPIL3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_115861.1|refseq:NP_570981.1|refseq:XP_011509660.1|refseq:XP_005246708.1|refseq:XP_005246709.1|refseq:XP_016859841.1|refseq:XP_016859842.1|refseq:XP_016859843.1|refseq:XP_016859844.1|refseq:XP_016859845.1|ensembl:ENSG00000240344(gene)|ensembl:ENST00000392283(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0006457"(protein folding)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|interpro:IPR044666|mint:Q9H2H8|rcsb pdb:1XYH|rcsb pdb:2OJU|rcsb pdb:2OK3|reactome:R-HSA-72163 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:jh7wemNjeR869z1vKLwDMjiFinQ9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q96M11 intact:EBI-25487684 intact:EBI-720016|uniprotkb:Q96BX9|uniprotkb:B3KXI8|ensembl:ENSP00000348815|ensembl:ENSP00000414884|ensembl:ENSP00000436833 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hyls1_human(display_long)|uniprotkb:HYLS1(gene name)|psi-mi:HYLS1(display_short)|uniprotkb:HLS(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001128265.1|refseq:NP_659451.1|ensembl:ENSG00000198331(gene)|ensembl:ENST00000356438(transcript)|ensembl:ENST00000425380(transcript)|ensembl:ENST00000526028(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0060271"(cilium assembly)|go:"GO:0097730"(non-motile cilium)|interpro:IPR026227|interpro:IPR027918|mint:Q96M11|refseq:XP_011540961.1|refseq:XP_005271487.1|refseq:XP_006718840.1|refseq:XP_016872809.1|refseq:XP_016872810.1 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:6qsYE/EnF7/lGKFARgoQtUurYrk9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q96IZ5 intact:EBI-25487684 intact:EBI-740773|uniprotkb:Q5JSN7|uniprotkb:Q5JSN8|uniprotkb:Q9H8F7|uniprotkb:Q9NV04|ensembl:ENSP00000361557 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rbm41_human(display_long)|uniprotkb:RNA-binding motif protein 41(gene name synonym)|uniprotkb:RBM41(gene name)|psi-mi:RBM41(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001164551.1|refseq:NP_060771.3|ensembl:ENSG00000089682(gene)|ensembl:ENST00000372479(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0030626"(U12 snRNA binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q96IZ5|rcsb pdb:2CPX - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:KHwyEjuJY+hrTu20ukqsVZldJx09606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q92908 intact:EBI-25487684 intact:EBI-2869259|uniprotkb:P78327|uniprotkb:B0YJ17|intact:EBI-28985406|ensembl:ENSP00000269216|ensembl:ENSP00000462313 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gata6_human(display_long)|uniprotkb:GATA6(gene name)|psi-mi:GATA6(display_short)|uniprotkb:GATA-binding factor 6(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_005248.2|ensembl:ENSP00000269216|ensembl:ENSP00000462313|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0060947"(cardiac vascular smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070848"(response to growth factor)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0098773"(skin epidermis development)|go:"GO:0048645"(animal organ formation)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|ensembl:ENSG00000141448(gene)|go:"GO:1904003"(negative regulation of sebum secreting cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR028437|interpro:IPR039355|mint:Q92908|reactome:R-HSA-5683826|reactome:R-HSA-983231|go:"GO:1901390"(positive regulation of transforming growth factor beta activation)|ensembl:ENST00000269216(transcript)|ensembl:ENST00000581694(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001889"(liver development)|go:"GO:0001949"(sebaceous gland cell differentiation)|go:"GO:0002759"(regulation of antimicrobial humoral response)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003310"(pancreatic A cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007493"(endodermal cell fate determination)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0032912"(negative regulation of transforming growth factor beta2 production)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding) - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:+pEu3biPLYjs3/QiV/Ozi1HR9iY9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q92615 intact:EBI-25487684 intact:EBI-1052558|uniprotkb:Q5T3R3|uniprotkb:Q5T3R4|uniprotkb:Q5T3R5|uniprotkb:Q68CY4|uniprotkb:A7MD20|intact:EBI-28969094|ensembl:ENSP00000326128 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lar4b_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 5(gene name synonym)|uniprotkb:LARP4B(gene name)|psi-mi:LARP4B(display_short)|uniprotkb:LARP5(gene name synonym)|uniprotkb:La-related protein 5(gene name synonym)|uniprotkb:KIAA0217(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 4B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_055970.1|ensembl:ENSP00000326128|ensembl:ENSG00000107929(gene)|ensembl:ENST00000316157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1905870"(positive regulation of 3'-UTR-mediated mRNA stabilization)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034900|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3PTH - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:tVFpPu0vhCgdRt0lowfi5GzA8Do9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q8TD31 intact:EBI-25487684 intact:EBI-949834|ensembl:ENSP00000365442|ensembl:ENSP00000372832|ensembl:ENSP00000373019|ensembl:ENSP00000383205|ensembl:ENSP00000393042|ensembl:ENSP00000408012|uniprotkb:Q9NRK8|uniprotkb:Q9NWY9|uniprotkb:Q9NXJ4|uniprotkb:Q9NXK3|uniprotkb:Q9Y6W1|uniprotkb:Q9Y6W2|uniprotkb:Q5SQ82|uniprotkb:Q5STE9|uniprotkb:A2ABH6|uniprotkb:Q2TB67|uniprotkb:E9PE84 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cchcr_human(display_long)|uniprotkb:Alpha-helical coiled-coil rod protein(gene name synonym)|uniprotkb:Putative gene 8 protein(gene name synonym)|uniprotkb:CCHCR1(gene name)|psi-mi:CCHCR1(display_short)|uniprotkb:C6orf18(gene name synonym)|uniprotkb:HCR(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000204536(gene)|ensembl:ENSG00000206355(gene)|ensembl:ENSG00000206457(gene)|ensembl:ENSG00000234114(gene)|ensembl:ENST00000376266(transcript)|ensembl:ENST00000383341(transcript)|ensembl:ENST00000383527(transcript)|ensembl:ENST00000400352(transcript)|ensembl:ENST00000416163(transcript)|ensembl:ENST00000425620(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0030154"(cell differentiation)|go:"GO:0042802"(identical protein binding)|interpro:IPR009800(Alpha helical coiled-coil rod)|go:"GO:0005814"(centriole)|refseq:XP_016866451.1|refseq:XP_016866452.1|refseq:XP_016866453.1|refseq:XP_016866454.1|refseq:XP_016866455.1|refseq:XP_016866456.1|refseq:XP_016866457.1|refseq:NP_001099033.1|refseq:NP_001099034.1|refseq:NP_061925.2|refseq:XP_011513005.1|dip:DIP-40394N - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:wgzA1VMrSlj7h29Hpmg5L0IOAJU9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q8IWR0 intact:EBI-25487684 intact:EBI-724271|ensembl:ENSP00000347999|ensembl:ENSP00000379773|uniprotkb:Q9NPE9|uniprotkb:D3DUG5 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:z3h7a_human(display_long)|uniprotkb:ZC3H7A(gene name)|psi-mi:ZC3H7A(display_short)|uniprotkb:ZC3H7(gene name synonym)|uniprotkb:ZC3HDC7(gene name synonym)|uniprotkb:HSPC055(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_054872.2|ensembl:ENSG00000122299(gene)|ensembl:ENST00000355758(transcript)|ensembl:ENST00000396516(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036236|interpro:IPR036855|interpro:IPR039691|mint:Q8IWR0|rcsb pdb:2D9M|refseq:XP_011520765.1|refseq:XP_006720940.1 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:9jUCQwl3/lLQ979tdqWlZ0Zszns9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q86SQ0 intact:EBI-25487684 intact:EBI-2798483|uniprotkb:Q68CY3|uniprotkb:Q8NCU5|uniprotkb:Q6NT98|uniprotkb:Q59EA8|uniprotkb:A5PKZ3|uniprotkb:Q8N8U8|uniprotkb:Q8NAB1|ensembl:ENSP00000377502|ensembl:ENSP00000405405 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:phlb2_human(display_long)|uniprotkb:LL5B(gene name synonym)|uniprotkb:Protein LL5-beta(gene name synonym)|uniprotkb:PHLDB2(gene name)|psi-mi:PHLDB2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001127909.1|refseq:NP_001127910.1|refseq:NP_001127911.1|refseq:NP_665696.1|ensembl:ENSG00000144824(gene)|ensembl:ENST00000393925(transcript)|ensembl:ENST00000431670(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0031252"(cell leading edge)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045180"(basal cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|dip:DIP-42196N - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:T5YIJ7WjxQlZKWAd/28wh3Znui89606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q70EL1 intact:EBI-25487684 intact:EBI-946185|intact:EBI-2798236|uniprotkb:B9ZVM1|uniprotkb:A1L4Q4|uniprotkb:A3KFK3|uniprotkb:A3KFK5|uniprotkb:A3KFK6|uniprotkb:A3KFK7|uniprotkb:A6PVS4|uniprotkb:A6PVS5|uniprotkb:A6PVS6|uniprotkb:A6PVS7|uniprotkb:B3KVY1|uniprotkb:Q5F2F4|uniprotkb:Q6ZSP1|uniprotkb:Q6ZSR1|uniprotkb:Q6ZTM0|uniprotkb:Q8N1X2|uniprotkb:Q6P1N6|ensembl:ENSP00000345216 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ubp54_human(display_long)|uniprotkb:C10orf29(gene name synonym)|uniprotkb:Inactive ubiquitin-specific peptidase 54(gene name synonym)|uniprotkb:USP54(gene name)|psi-mi:USP54(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_689799.3|refseq:NP_001307366.1|refseq:XP_016871263.1|refseq:XP_016871264.1|refseq:XP_016871265.1|refseq:XP_016871266.1|ensembl:ENSG00000166348(gene)|ensembl:ENST00000339859(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|interpro:IPR038765|interpro:IPR040142|mint:Q70EL1 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:TwMLO8uUiZ6onr+jyUz5D6qwZ1g9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q6ZRI6 intact:EBI-25487684 intact:EBI-724520|uniprotkb:C9J888|uniprotkb:Q71JB1|uniprotkb:Q7L3S0|uniprotkb:Q8N3F2|uniprotkb:Q96FB6|uniprotkb:Q9NTU5|uniprotkb:B3KWI3|intact:EBI-28984178|ensembl:ENSP00000353854|ensembl:ENSP00000378438 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:co039_human(display_long)|uniprotkb:C15orf39(gene name)|psi-mi:C15orf39(display_short)|uniprotkb:FP6578(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_056307.2|ensembl:ENSG00000167173(gene)|ensembl:ENST00000360639(transcript)|ensembl:ENST00000394987(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR037656|ensembl:ENSP00000353854|ensembl:ENSP00000378438|ensembl:ENST00000567617|ensembl:ENSP00000458025 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:VYd3afZ8a0S4gzUTVBYf5aTe7lw9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q6UUV7 intact:EBI-25487684 intact:EBI-3453588|uniprotkb:Q9H6U2|uniprotkb:Q6DK61|uniprotkb:Q6DK62|uniprotkb:Q8NF38|ensembl:ENSP00000268184 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:crtc3_human(display_long)|uniprotkb:CRTC3(gene name)|psi-mi:CRTC3(display_short)|uniprotkb:TORC3(gene name synonym)|uniprotkb:Transducer of regulated cAMP response element-binding protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001036039.1|refseq:NP_073606.3|ensembl:ENSP00000268184|ensembl:ENST00000420329|ensembl:ENSP00000416573|dip:DIP-59211N|ensembl:ENSG00000140577(gene)|ensembl:ENST00000268184(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR024786|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-9707616|go:"GO:0005829"(cytosol)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0097009"(energy homeostasis)|interpro:IPR024783|interpro:IPR024784|interpro:IPR024785 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:OHoNJjikyJ3RLDd+Y23mUXbtLDA9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q5VUA4 intact:EBI-25487684 intact:EBI-2849257|uniprotkb:Q8NEM6|uniprotkb:Q9UNU8|uniprotkb:Q4G0E4|uniprotkb:O94796|uniprotkb:Q9Y2W9|intact:EBI-28976662|ensembl:ENSP00000354964 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zn318_human(display_long)|uniprotkb:ZNF318(gene name)|psi-mi:ZNF318(display_short)|uniprotkb:Endocrine regulatory protein(gene name synonym)|uniprotkb:HRIHFB2436(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSP00000354964|ensembl:ENST00000605935|ensembl:ENSP00000475748|refseq:XP_011512754.1|refseq:NP_055160.2|ensembl:ENSG00000171467(gene)|ensembl:ENST00000361428(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003604(Zinc finger, U1-type) - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:HqHWYB1s5uaauSljuYFDb3/6XB49606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q5EBL8 intact:EBI-25487684 intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666|ensembl:ENSP00000363578 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509(gene)|ensembl:ENST00000239666(transcript)|ensembl:ENST00000374454(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q4KMZ1 intact:EBI-25487684 intact:EBI-12206419|ensembl:ENSP00000291358|uniprotkb:F5H7T8|uniprotkb:Q4KMS3|uniprotkb:Q4KMZ5|uniprotkb:Q53FL2|uniprotkb:Q5TFJ8|uniprotkb:Q9NVS3 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:iqcc_human(display_long)|uniprotkb:IQCC(gene name)|psi-mi:IQCC(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000160051(gene)|ensembl:ENST00000291358(transcript)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR042506|refseq:NP_001153514.1|refseq:NP_060604.2 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:9jGLDQ9G3ecrKucEK/LBIu/P8ZY9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q2T9J0 intact:EBI-25487684 intact:EBI-2510623|ensembl:ENSP00000287078|uniprotkb:Q8N6H2|uniprotkb:Q5SQU1|uniprotkb:Q96AR5|uniprotkb:Q5SQT4 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tysd1_human(display_long)|uniprotkb:TYSND1(gene name)|psi-mi:TYSND1(display_short)|uniprotkb:Trypsin domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000156521(gene)|ensembl:ENST00000287078(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0042802"(identical protein binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR017345(Peptidase S1B, Tysnd1)|interpro:IPR039245|reactome:R-HSA-9033241|reactome:R-HSA-9033500|go:"GO:0004252"(serine-type endopeptidase activity)|refseq:NP_001035363.1|refseq:NP_775826.2 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:nfBCzADhPAnpbY6GasKVCOaZjjs9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q2NL68 intact:EBI-25487684 intact:EBI-11336487|uniprotkb:Q8NDI3|uniprotkb:Q96NL4|uniprotkb:Q8WWC8|ensembl:ENSP00000380116 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:prsr3_human(display_long)|uniprotkb:PROSER3(gene name)|psi-mi:PROSER3(display_short)|uniprotkb:C19orf55(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001034976.2|ensembl:ENSG00000167595(gene)|ensembl:ENST00000396908(transcript)|interpro:IPR037646|refseq:XP_011524838.1 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:r9IIhUlY1pj+mQG/hbSx+5PhwCo9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q13948 intact:EBI-25487684 intact:EBI-1043463|uniprotkb:Q53GU9|uniprotkb:Q8TBS3|uniprotkb:B3KWH3|uniprotkb:B3KWH8|uniprotkb:B4DZZ2|uniprotkb:G3V1Z6|uniprotkb:J3KPQ6|ensembl:ENSP00000484760|ensembl:ENSP00000292538 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:casp_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001189473.1|refseq:NP_001189475.1|refseq:NP_001904.2|refseq:NP_852477.1|refseq:NP_001189474.1|ensembl:ENST00000292538(transcript)|ensembl:ENST00000622516(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030173"(integral component of Golgi membrane)|interpro:IPR012955(CASP, C-terminal)|reactome:R-HSA-6811438|ensembl:ENSG00000257923(gene) - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:wVbRcBsmnWoJ44GcliGkMzhZOFg9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q13615 intact:EBI-25487684 intact:EBI-371938|uniprotkb:Q9NYN5|uniprotkb:Q9NYN6|uniprotkb:Q9UDX6|uniprotkb:Q9UEG3|uniprotkb:A5PL26|uniprotkb:A7MD32|intact:EBI-28971617|ensembl:ENSP00000384651 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mtmr3_human(display_long)|uniprotkb:MTMR3(gene name)|psi-mi:MTMR3(display_short)|uniprotkb:FYVE domain-containing dual specificity protein phosphatase 1(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 10(gene name synonym)|uniprotkb:KIAA0371(gene name synonym)|uniprotkb:ZFYVE10(gene name synonym)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENST00000333027|ensembl:ENSP00000331649|ensembl:ENST00000351488|ensembl:ENSP00000307271|ensembl:ENSP00000384651|ensembl:ENST00000406629|ensembl:ENSP00000384077|refseq:NP_066576.1|refseq:NP_694690.1|refseq:NP_694691.1|ensembl:ENSG00000100330(gene)|ensembl:ENST00000401950(transcript)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR010569(Myotubularin-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR029021|interpro:IPR030564|interpro:IPR035888|mint:Q13615|reactome:R-HSA-1632852|reactome:R-HSA-1660499|refseq:XP_016884521.1 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:6YquGTCQYgFfrhdj1Iqtzgd9tP49606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q13546 intact:EBI-25487684 intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|ensembl:ENSG00000137275(gene)|ensembl:ENST00000259808(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0010008"(endosome membrane)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043235"(receptor complex)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070513"(death domain binding)|go:"GO:0070926"("regulation of ATP:ADP antiporter activity")|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097342"(ripoptosome)|go:"GO:0097343"(ripoptosome assembly)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR025735|interpro:IPR037934|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9693928|go:"GO:0070266"(necroptotic process) - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:Q13033 intact:EBI-25487684 intact:EBI-1053857|uniprotkb:Q9NRA5|uniprotkb:A6NHZ7|uniprotkb:A2RTX7|ensembl:ENSP00000350071 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:strn3_human(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:STRN3(gene name)|psi-mi:STRN3(display_short)|uniprotkb:GS2NA(gene name synonym)|uniprotkb:SG2NA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001077362.1|refseq:NP_055389.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q13033|rcsb pdb:4N6J|rcsb pdb:6AKL|rcsb pdb:6IUR|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|rcsb pdb:7K36|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000196792(gene)|ensembl:ENST00000357479(transcript) - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:gGqyj/yXjaB436zEu/pEoPzhnRQ9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:O95391 intact:EBI-25487684 intact:EBI-750559|uniprotkb:Q3LUJ0|uniprotkb:Q3LUJ1|uniprotkb:Q6RXQ5|uniprotkb:Q96FM9|uniprotkb:D3DQK2|ensembl:ENSP00000297151 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:slu7_human(display_long)|uniprotkb:SLU7(gene name)|psi-mi:SLU7(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:XP_011532720.1|refseq:NP_006416.3|ensembl:ENSG00000164609(gene)|ensembl:ENST00000297151(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000386"(second spliceosomal transesterification activity)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR021715|interpro:IPR039974|mint:O95391|rcsb pdb:5XJC|rcsb pdb:6ICZ|rcsb pdb:6QDV|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0043231"(intracellular membrane-bounded organelle) - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:AYvUYw2HWT1ZgCOR3UJMXsfm1Bc9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:O75506 intact:EBI-25487684 intact:EBI-748664|uniprotkb:Q7Z5Z3|uniprotkb:Q53XA8|ensembl:ENSP00000392896|ensembl:ENSP00000458007 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hsbp1_human(display_long)|uniprotkb:Nasopharyngeal carcinoma-associated antigen 13(gene name synonym)|uniprotkb:HSBP1(gene name)|psi-mi:HSBP1(display_short)|uniprotkb:HSF1BP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001528.1|interpro:IPR009643(Heat shock factor binding 1)|rcsb pdb:3CI9|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|ensembl:ENSG00000230989(gene)|ensembl:ENST00000433866(transcript)|ensembl:ENST00000570259(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0070370"(cellular heat acclimation) - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:3JML7OxHIw8M91ARKPfOhJ9kVbk9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:O43303 intact:EBI-25487684 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:O15182 intact:EBI-25487684 intact:EBI-712959|ensembl:ENSP00000283122|uniprotkb:Q53YD2|uniprotkb:Q9BS23 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cetn3_human(display_long)|uniprotkb:CETN3(gene name)|psi-mi:CETN3(display_short)|uniprotkb:CEN3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENST00000283122(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|ensembl:ENSG00000153140(gene)|go:"GO:0051301"(cell division)|go:"GO:0070390"(transcription export complex 2)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|refseq:NP_004356.2|refseq:NP_001284697.1 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:m0uBq6ZNOxGDC2kU8i8rDRlVS6s9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:O15014 intact:EBI-25487684 intact:EBI-948874|intact:EBI-28988504|ensembl:ENSP00000316527|uniprotkb:Q0D2I2 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zn609_human(display_long)|uniprotkb:ZNF609(gene name)|psi-mi:ZNF609(display_short)|uniprotkb:KIAA0295(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) dip:DIP-50012N|ensembl:ENSG00000180357(gene)|ensembl:ENST00000326648(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR040010|mint:O15014|refseq:NP_055857.1|refseq:XP_011519688.1|ensembl:ENSP00000316527|refseq:XP_016877510.1 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:lg9CqF10xeIzDGib19G9feQpBIY9606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037318 uniprotkb:A3KN83 intact:EBI-25487684 intact:EBI-2855422|uniprotkb:Q9H3T8|uniprotkb:Q05C06|uniprotkb:Q9NVB2|uniprotkb:Q3ZTS3|ensembl:ENSP00000387361|ensembl:ENSP00000473665 psi-mi:p0c6x7-pro_0000037318(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sbno1_human(display_long)|uniprotkb:SBNO1(gene name)|psi-mi:SBNO1(display_short)|uniprotkb:MOP3(gene name synonym)|uniprotkb:Monocyte protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26376977|imex:IM-28441-135 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:XP_011536835.1|refseq:XP_006719536.1|refseq:XP_006719537.1|refseq:XP_016875045.1|refseq:NP_001161328.1|refseq:NP_060653.3|refseq:XP_005253630.1|refseq:XP_005253633.1|ensembl:ENSG00000139697(gene)|ensembl:ENST00000420886(transcript)|ensembl:ENST00000602398(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042393"(histone binding)|interpro:IPR026741|interpro:IPR026937|interpro:IPR027417|interpro:IPR039187 - chain-seq-start:4370|chain-seq-end:5301 - figure legend:Table 2, no 7|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:eeAJDsSyQ9Qfnm1xY+XJWlCGwWY694009 rogid:6Cq/LZqinhg1CXC/2L1JyZygCc89606 rigid:cqgOaMTm4pyhJPGBzzJWTr2T1GM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P17612 intact:EBI-25487926 intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9Y2I6 intact:EBI-25487926 intact:EBI-719716|uniprotkb:A6NJN0|uniprotkb:B3V9H6|uniprotkb:B7Z1V8|uniprotkb:Q8NE38|uniprotkb:Q9NQE3|intact:EBI-741715|uniprotkb:Q5JYP0|ensembl:ENSP00000278886 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ninl_human(display_long)|uniprotkb:NINL(gene name)|psi-mi:NINL(display_short)|uniprotkb:KIAA0980(gene name synonym)|uniprotkb:NLP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_079452.3|refseq:NP_001305155.1|ensembl:ENSG00000101004(gene)|ensembl:ENST00000278886(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:NAG+S5iboAG+mjX9ISJ05gY2lJY9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q8WWI1 intact:EBI-25487926 intact:EBI-350367|uniprotkb:O15462|uniprotkb:O95346|uniprotkb:Q9UKC1|uniprotkb:Q9UQM5|uniprotkb:Q9Y6A7|uniprotkb:Q5TBK6|uniprotkb:E9PLH4 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:lmo7_human(display_long)|uniprotkb:LMO7(gene name)|psi-mi:LMO7(display_short)|uniprotkb:FBX20(gene name synonym)|uniprotkb:FBXO20(gene name synonym)|uniprotkb:KIAA0858(gene name synonym)|uniprotkb:F-box only protein 20(gene name synonym)|uniprotkb:LOMP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_005349.3|refseq:NP_056667.2|refseq:NP_001293009.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0000151"(ubiquitin ligase complex)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003096(SM22/calponin)|interpro:IPR029978|interpro:IPR031865|interpro:IPR036034|interpro:IPR036872|rcsb pdb:2EAQ|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENST00000341547|ensembl:ENSP00000342112|ensembl:ENSG00000136153|refseq:NP_001317512.1|mint:Q8WWI1|dip:DIP-33107N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:d8c3oZaqaloIUBqxgvpNI3PP2fU9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q8N4C6 intact:EBI-25487926 intact:EBI-1164022|uniprotkb:Q6P0P6|uniprotkb:Q9BWU6|uniprotkb:Q9C012|uniprotkb:Q9C013|uniprotkb:Q9C014|uniprotkb:Q9H5I6|uniprotkb:Q9HAT7|uniprotkb:Q9HBY5|uniprotkb:Q9HCK7|uniprotkb:Q9UH61|uniprotkb:A6NDB8|uniprotkb:B7WPA3|uniprotkb:C9JSB6|uniprotkb:C9JSG2|uniprotkb:C9JXL2|ensembl:ENSP00000371472|uniprotkb:Q5BKU3 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:nin_human(display_long)|uniprotkb:Glycogen synthase kinase 3 beta-interacting protein(gene name synonym)|uniprotkb:NIN(gene name)|psi-mi:NIN(display_short)|uniprotkb:KIAA1565(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:XP_011535125.1|ensembl:ENSG00000100503(gene)|ensembl:ENST00000382041(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|refseq:NP_057434.4|refseq:NP_065972.3|refseq:NP_891989.2|refseq:NP_891991.1|go:"GO:0005814"(centriole)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019900"(kinase binding)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045177"(apical part of cell)|go:"GO:0048668"(collateral sprouting)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090222"(centrosome-templated microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097539"(ciliary transition fiber)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR029664|mint:Q8N4C6|go:"GO:0034454"(microtubule anchoring at centrosome) - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:ZvO0amOxGf+HZIxnXTYCqpnzTjw9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P35579 intact:EBI-25487926 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9Y608 intact:EBI-25487926 intact:EBI-1023718|uniprotkb:Q68CV3|uniprotkb:Q9NXH5|uniprotkb:A8K649|uniprotkb:A8MXR0|uniprotkb:B4DY63|ensembl:ENSP00000338727 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:lrrf2_human(display_long)|uniprotkb:LRRFIP2(gene name)|psi-mi:LRRFIP2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001127841.1|refseq:NP_006300.1|refseq:NP_060194.1|refseq:XP_011532519.1|refseq:XP_011532520.1|refseq:XP_011532521.1|refseq:NP_001269620.1|ensembl:ENSG00000093167(gene)|ensembl:ENST00000336686(transcript)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030275"(LRR domain binding)|interpro:IPR019139|mint:Q9Y608|refseq:XP_005265596.1|refseq:XP_005265597.1|refseq:XP_016862973.1|refseq:NP_001335239.1|refseq:NP_001335240.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:ma/crL7UY91uJ8bqLfkX3K8aQLI9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9Y4I1 intact:EBI-25487926 intact:EBI-1054086|uniprotkb:O60653|uniprotkb:Q07902|uniprotkb:Q16249|uniprotkb:Q9UE30|uniprotkb:Q9UE31|uniprotkb:A8MZC5|ensembl:ENSP00000382177 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myo5a_human(display_long)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym)|uniprotkb:Myosin heavy chain 12(gene name synonym)|uniprotkb:Myoxin(gene name synonym)|uniprotkb:MYO5A(gene name)|psi-mi:MYO5A(display_short)|uniprotkb:MYH12(gene name synonym)|uniprotkb:Myosin-12(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_000250.3|refseq:XP_005254454.1|ensembl:ENSG00000197535(gene)|ensembl:ENST00000399231(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030426"(growth cone)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032433"(filopodium tip)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|interpro:IPR037988|mint:Q9Y4I1|rcsb pdb:4D07|rcsb pdb:4J5L|rcsb pdb:4LLI|rcsb pdb:4LX1|rcsb pdb:4LX2|rcsb pdb:5JCY|rcsb pdb:5JCZ|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-264876|reactome:R-HSA-9664422 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:z4bbPG/RrXSmBWT6I0nbIztGp809606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9UPQ0 intact:EBI-25487926 intact:EBI-2687222|uniprotkb:Q8N3S9|uniprotkb:Q5H9S8|uniprotkb:Q6PJ44|uniprotkb:Q5CZB6|uniprotkb:Q5CZB1|uniprotkb:Q503B5|uniprotkb:Q8N6M2|uniprotkb:Q68E07|uniprotkb:Q7Z3G5|uniprotkb:A8MXC3|uniprotkb:E9PHM7|intact:EBI-10977823|ensembl:ENSP00000316891 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:limc1_human(display_long)|uniprotkb:KIAA1102(gene name synonym)|uniprotkb:LIMCH1(gene name)|psi-mi:LIMCH1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001106188.1|refseq:NP_001106189.1|refseq:NP_001106190.1|refseq:NP_001106191.1|refseq:NP_055803.2|refseq:NP_001276051.1|refseq:NP_001276053.1|ensembl:ENSG00000064042(gene)|ensembl:ENST00000313860(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029980|interpro:IPR031865|interpro:IPR036872|refseq:NP_001317601.1|refseq:NP_001317603.1|refseq:NP_001317713.1|refseq:NP_001317715.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:neDT1Rx97o6shpmtkOqJy31ueTA9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9UPN4 intact:EBI-25487926 intact:EBI-2558372|uniprotkb:B2RN11|uniprotkb:Q96F50|uniprotkb:A6NHI8|ensembl:ENSP00000269392 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cp131_human(display_long)|uniprotkb:CEP131(gene name)|psi-mi:CEP131(display_short)|uniprotkb:5-azacytidine-induced protein 1(gene name synonym)|uniprotkb:AZI1(gene name synonym)|uniprotkb:KIAA1118(gene name synonym)|uniprotkb:Pre-acrosome localization protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001009811.2|refseq:NP_055799.2|refseq:NP_001306157.1|ensembl:ENSG00000141577(gene)|ensembl:ENST00000269392(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0120212"(sperm head-tail coupling apparatus)|go:"GO:1905198"(manchette assembly)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990953"(intramanchette transport)|interpro:IPR030465|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005814"(centriole)|dip:DIP-56658N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:qcnzG6vfogSEappaH9nv7P3kSoQ9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9UM54 intact:EBI-25487926 intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9ULV0 intact:EBI-25487926 intact:EBI-311356|uniprotkb:B0I1R3|uniprotkb:Q0P656|uniprotkb:Q9H6Y6|intact:EBI-28979562|ensembl:ENSP00000285039 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myo5b_human(display_long)|uniprotkb:MYO5B(gene name)|psi-mi:MYO5B(display_short)|uniprotkb:KIAA1119(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSP00000285039|ensembl:ENST00000592688|ensembl:ENSP00000466368|ensembl:ENSG00000167306(gene)|ensembl:ENST00000285039(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045179"(apical cortex)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|interpro:IPR037990|mint:Q9ULV0|rcsb pdb:4J5M|rcsb pdb:4LNZ|rcsb pdb:4LWZ|rcsb pdb:4LX0|reactome:R-HSA-432040|refseq:NP_001073936.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:p6fM9FBgui27LRlshWAjPe47Ftc9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9H0E2 intact:EBI-25487926 intact:EBI-74615|ensembl:ENSP00000314733|uniprotkb:Q9H9E6|uniprotkb:Q9UJ69|uniprotkb:B3KXC6 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tolip_human(display_long)|uniprotkb:TOLLIP(gene name)|psi-mi:TOLLIP(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000078902(gene)|ensembl:ENST00000317204(transcript)|go:"GO:0005150"(interleukin-1, type I receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0016310"(phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0006954"(inflammatory response)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045321"(leukocyte activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR035892|interpro:IPR037301|interpro:IPR041799|rcsb pdb:1WGL|rcsb pdb:2N31|reactome:R-HSA-6798695|reactome:R-HSA-9020702|refseq:NP_061882.2|refseq:NP_001305441.1|refseq:NP_001305443.1|refseq:NP_001305444.1|refseq:NP_001305445.1|dip:DIP-30845N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:HR6/CGVYMtuDqxW44fBD/KjScnk9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9BZF9 intact:EBI-25487926 intact:EBI-350510|uniprotkb:Q14DD3|uniprotkb:Q8N3B8|uniprotkb:Q9HCL1|uniprotkb:Q9NWC6|uniprotkb:G3XAG2|uniprotkb:Q96NH6|intact:EBI-10977773|ensembl:ENSP00000314556 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:uaca_human(display_long)|uniprotkb:UACA(gene name)|psi-mi:UACA(display_short)|uniprotkb:KIAA1561(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001008225.1|refseq:NP_060473.2|dip:DIP-33117N|ensembl:ENSG00000137831(gene)|ensembl:ENST00000322954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030227|interpro:IPR036770|mint:Q9BZF9|reactome:R-HSA-9013407|reactome:R-HSA-9627069 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:F58VkGk2DBsUUrB+wgknUFZhJ+E9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9BV73 intact:EBI-25487926 intact:EBI-1053100|uniprotkb:O14812|uniprotkb:O60588|uniprotkb:Q9H450|uniprotkb:E1P5Q3|ensembl:ENSP00000380661 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cp250_human(display_long)|uniprotkb:Centrosomal protein 2(gene name synonym)|uniprotkb:Centrosomal Nek2-associated protein 1(gene name synonym)|uniprotkb:CEP250(gene name)|psi-mi:CEP250(display_short)|uniprotkb:CEP2(gene name synonym)|uniprotkb:CNAP1(gene name synonym)|uniprotkb:250 kDa centrosomal protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_009117.2|dip:DIP-39406N|refseq:NP_001305148.1|refseq:XP_005260319.1|refseq:XP_006723753.1|refseq:XP_006723754.1|refseq:XP_006723755.1|refseq:XP_006723756.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|mint:Q9BV73|rcsb pdb:6OQA|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000126001(gene)|ensembl:ENST00000397527(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0060271"(cilium assembly) - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:We+5inOR7merXjzOl/vRehewlFA9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9BV19 intact:EBI-25487926 intact:EBI-2874661|ensembl:ENSP00000361603 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ca050_human(display_long)|uniprotkb:C1orf50(gene name)|psi-mi:C1orf50(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000164008(gene)|ensembl:ENST00000372525(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR019534|refseq:NP_077002.2 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:TZfvza3lr44CQW5Piu+83qv5Igo9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q9BQQ3 intact:EBI-25487926 intact:EBI-2561458|uniprotkb:Q3SYG7|uniprotkb:Q96H42|uniprotkb:Q8N272|uniprotkb:B3KWC8|ensembl:ENSP00000313869 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:gors1_human(display_long)|uniprotkb:GORASP1(gene name)|psi-mi:GORASP1(display_short)|uniprotkb:GOLPH5(gene name synonym)|uniprotkb:GRASP65(gene name synonym)|uniprotkb:Golgi reassembly-stacking protein of 65 kDa(gene name synonym)|uniprotkb:Golgi peripheral membrane protein p65(gene name synonym)|uniprotkb:Golgi phosphoprotein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_114105.1|refseq:NP_001265718.1|refseq:NP_001265719.1|ensembl:ENSG00000114745(gene)|ensembl:ENST00000319283(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|rcsb pdb:4REY|rcsb pdb:6G8T|rcsb pdb:6G8W|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:gCTXn0H+UPamtVxyvChrMrcQvCA9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q99996 intact:EBI-25487926 intact:EBI-1048311|uniprotkb:O14869|uniprotkb:O43355|uniprotkb:O94895|uniprotkb:Q75N20|uniprotkb:Q9UQH3|uniprotkb:Q9UQQ4|uniprotkb:Q9Y6B8|uniprotkb:A4D1F0|uniprotkb:Q9Y6Y2|uniprotkb:A4D1F2|uniprotkb:A4D1F4|ensembl:ENSP00000348573 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:akap9_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)|uniprotkb:A-kinase anchor protein 450 kDa(gene name synonym)|uniprotkb:A-kinase anchor protein 350 kDa(gene name synonym)|uniprotkb:AKAP 120-like protein(gene name synonym)|uniprotkb:Protein hyperion(gene name synonym)|uniprotkb:Protein yotiao(gene name synonym)|uniprotkb:Centrosome- and Golgi-localized PKN-associated protein(gene name synonym)|uniprotkb:AKAP9(gene name)|psi-mi:AKAP9(display_short)|uniprotkb:AKAP350(gene name synonym)|uniprotkb:AKAP450(gene name synonym)|uniprotkb:KIAA0803(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_005742.4|refseq:NP_671714.1|ensembl:ENSG00000127914(gene)|ensembl:ENST00000356239(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044307"(dendritic branch)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR005539(ELK)|interpro:IPR019528|interpro:IPR028745|mint:Q99996|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5576890|reactome:R-HSA-5576893|reactome:R-HSA-5620912|reactome:R-HSA-6802952|reactome:R-HSA-8854518|ensembl:ENSP00000348573|ensembl:ENST00000680766|ensembl:ENSP00000505204|dip:DIP-29942N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:LQUNbTHUgEsjayFEZvczC4e90Nw9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q96SN8 intact:EBI-25487926 intact:EBI-308374|uniprotkb:Q7Z3L4|uniprotkb:Q7Z3U1|uniprotkb:Q7Z7I6|uniprotkb:Q9BSW0|uniprotkb:Q9H6J6|uniprotkb:Q9HCD9|uniprotkb:Q9NV90|uniprotkb:Q9UIW9|uniprotkb:Q5JV18|ensembl:ENSP00000343818 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ck5p2_human(display_long)|uniprotkb:CDK5RAP2(gene name)|psi-mi:CDK5RAP2(display_short)|uniprotkb:KIAA1633(gene name synonym)|uniprotkb:CDK5 activator-binding protein C48(gene name synonym)|uniprotkb:Centrosome-associated protein 215(gene name synonym)|uniprotkb:CEP215(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001011649.1|ensembl:ENSG00000136861(gene)|ensembl:ENST00000349780(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007099"(centriole replication)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR012943(Spindle associated)|mint:Q96SN8|rcsb pdb:6X0V|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_060719.4|refseq:NP_001258968.1|refseq:XP_006717245.1|dip:DIP-31632N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:/XamYFvD5N/npIkOGnLQkZzmBnU9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q96N16 intact:EBI-25487926 intact:EBI-2680803|uniprotkb:A6H2J5|uniprotkb:A6H2J4|uniprotkb:B8ZZR7|uniprotkb:Q8N7G3|uniprotkb:A6H2J2|uniprotkb:A6H2J3|uniprotkb:Q86Y69|uniprotkb:A8MTK6|intact:EBI-2812508|uniprotkb:D3DVT0|ensembl:ENSP00000282924|ensembl:ENSP00000386925|uniprotkb:B4DHZ8 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:jkip1_human(display_long)|uniprotkb:GABABRBP(gene name synonym)|uniprotkb:JAMIP1(gene name synonym)|uniprotkb:MARLIN1(gene name synonym)|uniprotkb:GABA-B receptor-binding protein(gene name synonym)|uniprotkb:Multiple alpha-helices and RNA-linker protein 1(gene name synonym)|uniprotkb:JAKMIP1(gene name)|psi-mi:JAKMIP1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001293062.1|refseq:NP_001293063.1|refseq:XP_011511702.1|refseq:NP_001092903.1|refseq:NP_653321.1|ensembl:ENSG00000152969(gene)|ensembl:ENST00000282924(transcript)|ensembl:ENST00000409831(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050890"(cognition)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR024836|interpro:IPR031994|mint:Q96N16|refseq:XP_016863282.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:tqQJu7pAUKeq6SOKhVJKm2u02mY9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q96II8 intact:EBI-25487926 intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q92995 intact:EBI-25487926 intact:EBI-714351|uniprotkb:D3DNS2|uniprotkb:Q96B25|intact:EBI-28978985|ensembl:ENSP00000263966|uniprotkb:A8K2S3|uniprotkb:B4DYF3 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ubp13_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 13(gene name synonym)|uniprotkb:Deubiquitinating enzyme 13(gene name synonym)|uniprotkb:Isopeptidase T-3(gene name synonym)|uniprotkb:USP13(gene name)|psi-mi:USP13(display_short)|uniprotkb:ISOT3(gene name synonym)|uniprotkb:Ubiquitin thioesterase 13(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_003931.2|ensembl:ENSG00000058056(gene)|ensembl:ENST00000263966(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044313"(protein K6-linked deubiquitination)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR009060(UBA-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016652(Ubiquitinyl hydrolase)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|interpro:IPR041432|rcsb pdb:2L80|rcsb pdb:2LBC|reactome:R-HSA-5689880|reactome:R-HSA-8948751|ensembl:ENSP00000263966|ensembl:ENST00000496897|ensembl:ENSP00000417146|dip:DIP-53511N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:q6g2QmSYm3Xjoo+tv20s6cN8iHk9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q92614 intact:EBI-25487926 intact:EBI-949059|ensembl:ENSP00000437073|uniprotkb:Q5H9U3|uniprotkb:Q5W9F9|uniprotkb:Q5W9G1|uniprotkb:Q8IXP8|uniprotkb:Q5QD01 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:my18a_human(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) dip:DIP-46631N|ensembl:ENSG00000196535(gene)|ensembl:ENST00000527372(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016477"(cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|go:"GO:1903028"(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR020587|interpro:IPR027417|interpro:IPR031244|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|interpro:IPR041489|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:NP_510880.2|refseq:NP_976063.1|refseq:NP_001333696.1|refseq:NP_001333697.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:IunEYt79RO62wU6VU2gv16Xb7Lk9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q8WXW3 intact:EBI-25487926 intact:EBI-2558770|uniprotkb:Q96SF4|uniprotkb:Q86V07|uniprotkb:Q6U9V2|uniprotkb:O95664|uniprotkb:Q6UG50|ensembl:ENSP00000317144 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:pibf1_human(display_long)|uniprotkb:PIBF1(gene name)|psi-mi:PIBF1(display_short)|uniprotkb:C13orf24(gene name synonym)|uniprotkb:PIBF(gene name synonym)|uniprotkb:Centrosomal protein of 90 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_006337.2|ensembl:ENSG00000083535(gene)|ensembl:ENST00000326291(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005136"(interleukin-4 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032815"(negative regulation of natural killer cell activation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026205|mint:Q8WXW3|dip:DIP-56669N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:830BcMpvq9x1Dg1ybOjNg/y4BH09606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q8TD10 intact:EBI-25487926 intact:EBI-2548751|ensembl:ENSP00000333539|ensembl:ENSP00000379589|ensembl:ENSP00000444254|ensembl:ENSP00000506738|uniprotkb:Q7Z3J0|uniprotkb:Q8IV14|uniprotkb:D3DSA4 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:mipo1_human(display_long)|uniprotkb:MIPOL1(gene name)|psi-mi:MIPOL1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000151338(gene)|ensembl:ENST00000327441(transcript)|ensembl:ENST00000396294(transcript)|ensembl:ENST00000537471(transcript)|ensembl:ENST00000684589(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR026175|mint:Q8TD10|refseq:NP_001182225.1|refseq:NP_001182226.1|refseq:NP_620059.1|refseq:XP_016876492.1|refseq:XP_016876493.1|refseq:XP_016876494.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:X4gY7nzDtnrS2yil7QhmLH968Ug9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q8IUD2 intact:EBI-25487926 intact:EBI-1044755|uniprotkb:Q6NVK2|uniprotkb:Q8IUD3|uniprotkb:Q8IUD4|uniprotkb:Q8IUD5|uniprotkb:Q8NAS1|uniprotkb:Q9NXN5|uniprotkb:Q9UIK7|uniprotkb:Q9UPS1|intact:EBI-3645200|uniprotkb:A7E295|ensembl:ENSP00000354158|ensembl:ENSP00000468263|uniprotkb:D3DUP7|uniprotkb:D3DUP8|uniprotkb:A2RU77 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:rb6i2_human(display_long)|uniprotkb:Rab6-interacting protein 2(gene name synonym)|uniprotkb:ERC1(gene name)|psi-mi:ERC1(display_short)|uniprotkb:ELKS(gene name synonym)|uniprotkb:KIAA1081(gene name synonym)|uniprotkb:RAB6IP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_829883.1|refseq:NP_829884.1|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0015031"(protein transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0007275"(multicellular organism development)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR019018|interpro:IPR019323|interpro:IPR037245|ensembl:ENSG00000082805(gene)|ensembl:ENST00000360905(transcript)|ensembl:ENST00000589028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|refseq:XP_016874553.1|refseq:XP_016874556.1|refseq:XP_011519243.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:0W5DM0QbKuWdMW4T+pJKPT7pKgA9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q7Z406 intact:EBI-25487926 intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|ensembl:ENSP00000366169|ensembl:ENSP00000472819|uniprotkb:C3TTN4 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_011525625.1|ensembl:ENSG00000105357(gene)|ensembl:ENST00000376970(transcript)|ensembl:ENST00000596571(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|interpro:IPR002928(Myosin tail)|refseq:XP_006723449.1|dip:DIP-33170N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q6ZVM7 intact:EBI-25487926 intact:EBI-3452240|uniprotkb:Q96M88|uniprotkb:Q86V61|uniprotkb:Q8TDE7|uniprotkb:B7Z7F4|ensembl:ENSP00000368818|uniprotkb:B7Z2L7 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tm1l2_human(display_long)|uniprotkb:TOM1L2(gene name)|psi-mi:TOM1L2(display_short)|uniprotkb:Target of Myb-like protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001028723.1|refseq:NP_001076437.1|refseq:NP_001275715.1|refseq:NP_001275716.1|refseq:NP_001275717.1|refseq:NP_001275718.1|ensembl:ENSG00000175662(gene)|ensembl:ENST00000379504(transcript)|go:"GO:0005768"(endosome)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR027429|interpro:IPR038425|dip:DIP-61860N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:NZ3MLjhsMwb65v0h0qjwkpZjZJ09606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q66GS9 intact:EBI-25487926 intact:EBI-1046993|uniprotkb:O75130|uniprotkb:Q9H8H7|uniprotkb:B2RMY0|uniprotkb:Q58F25|ensembl:ENSP00000257287|intact:EBI-1058323 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cp135_human(display_long)|uniprotkb:Centrosomal protein 4(gene name synonym)|uniprotkb:CEP135(gene name)|psi-mi:CEP135(display_short)|uniprotkb:CEP4(gene name synonym)|uniprotkb:KIAA0635(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_079285.2|rcsb pdb:5FCN|rcsb pdb:5NG4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|ensembl:ENSG00000174799(gene)|ensembl:ENST00000257287(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007099"(centriole replication)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR026732|mint:Q66GS9|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-50271N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:x/sbJVIQUS2zD/l2SQsmV5HwKP89606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q5VUJ6 intact:EBI-25487926 intact:EBI-2659666|uniprotkb:Q9P233|uniprotkb:Q9HA88|uniprotkb:F5H2T1|uniprotkb:Q08AD5|ensembl:ENSP00000325091 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:lrch2_human(display_long)|uniprotkb:KIAA1495(gene name synonym)|uniprotkb:LRCH2(gene name)|psi-mi:LRCH2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_065922.3|refseq:NP_001230892.1|ensembl:ENSG00000130224(gene)|ensembl:ENST00000317135(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:hjJwBxAeVmoDWTtcKK5NzCIDnBo9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q5VU43 intact:EBI-25487926 intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q5VT06 intact:EBI-25487926 intact:EBI-947346|uniprotkb:O75068|uniprotkb:Q8TDK3|uniprotkb:Q8WY20|ensembl:ENSP00000356579 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ce350_human(display_long)|uniprotkb:CEP350(gene name)|psi-mi:CEP350(display_short)|uniprotkb:CAP350(gene name synonym)|uniprotkb:GM133(orf name)|uniprotkb:KIAA0480(gene name synonym)|uniprotkb:Centrosome-associated protein of 350 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_055625.4|dip:DIP-49946N|ensembl:ENSG00000135837(gene)|ensembl:ENST00000367607(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042995"(cell projection)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR025486|interpro:IPR028750|interpro:IPR036859|rcsb pdb:2COZ - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:lwAOfFoQPaS6NHQ1NkmFWBfVA3s9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q15154 intact:EBI-25487926 intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q14789 intact:EBI-25487926 intact:EBI-709973|uniprotkb:Q14398|uniprotkb:D3DN92|uniprotkb:F1T0J2|uniprotkb:B2ZZ91|uniprotkb:E7EP74|ensembl:ENSP00000341848 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:gogb1_human(display_long)|uniprotkb:Giantin(gene name synonym)|uniprotkb:Macrogolgin(gene name synonym)|uniprotkb:372 kDa Golgi complex-associated protein(gene name synonym)|uniprotkb:GOLGB1(gene name)|psi-mi:GOLGB1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_004478.3|refseq:XP_011511001.1|refseq:NP_001243416.1|refseq:NP_001243417.1|refseq:XP_005247428.1|refseq:NP_001243415.1|dip:DIP-34649N|ensembl:ENSG00000173230(gene)|ensembl:ENST00000340645(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1905793"(protein localization to pericentriolar material)|interpro:IPR003106(Leucine zipper, homeobox-associated)|interpro:IPR026202|mint:Q14789|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-9703465 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:suoNOGzPA2FjQsHQs4cdSpqYn/M9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q13045 intact:EBI-25487926 intact:EBI-351549|ensembl:ENSP00000491480|ensembl:ENSP00000324573|uniprotkb:B4DIL0|uniprotkb:F5H407|uniprotkb:J3QLG3 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:flii_human(display_long)|uniprotkb:FLII(gene name)|psi-mi:FLII(display_short)|uniprotkb:FLIL(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_002009.1|refseq:NP_001243193.1|ensembl:ENST00000327031(transcript)|ensembl:ENST00000638207(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030239"(myofibril assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR029919|interpro:IPR032675|mint:Q13045|ensembl:ENSG00000177731(gene)|ensembl:ENSG00000284571(gene)|refseq:NP_001243194.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:hzls0Ir+lr0+wNsTUeIURV3fXVQ9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q12965 intact:EBI-25487926 intact:EBI-4279548|uniprotkb:Q14778|ensembl:ENSP00000288235 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myo1e_human(display_long)|uniprotkb:Myosin-Ic(gene name synonym)|uniprotkb:MYO1E(gene name)|psi-mi:MYO1E(display_short)|uniprotkb:MYO1C(gene name synonym)|uniprotkb:Unconventional myosin 1E(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_004989.2|ensembl:ENSG00000157483(gene)|ensembl:ENST00000288235(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001452(Src homology-3)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR035507|interpro:IPR036028|interpro:IPR036072|interpro:IPR036961|mint:Q12965|ensembl:ENSP00000288235|dip:DIP-884N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:UyG3wKoRwL2Eaw9CM6561vld+PU9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q08379 intact:EBI-25487926 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q08378 intact:EBI-25487926 intact:EBI-355782|uniprotkb:O43241|uniprotkb:Q6P9C7|uniprotkb:Q86XW3|uniprotkb:Q8TDA9|uniprotkb:Q8WZA3|uniprotkb:A5PKX6|intact:EBI-28985028|ensembl:ENSP00000204726|ensembl:ENSP00000410378 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:goga3_human(display_long)|uniprotkb:GOLGA3(gene name)|psi-mi:GOLGA3(display_short)|uniprotkb:Golgin-160(gene name synonym)|uniprotkb:Golgi complex-associated protein of 170 kDa(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001166028.1|refseq:NP_005886.2|ensembl:ENSP00000204726|ensembl:ENSP00000410378|ensembl:ENST00000456883|ensembl:ENSP00000409303|ensembl:ENST00000545875|ensembl:ENSP00000442603|ensembl:ENSG00000090615(gene)|ensembl:ENST00000204726(transcript)|ensembl:ENST00000450791(transcript)|go:"GO:0045296"(cadherin binding)|go:"GO:0090498"(extrinsic component of Golgi membrane)|interpro:IPR033288|mint:Q08378|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9696270|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|refseq:XP_006719799.1|refseq:XP_006719800.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:7AjSzX3sUzfKpZkvdKDM0L//zYM9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q04726 intact:EBI-25487926 intact:EBI-1052057|uniprotkb:Q8IVV6|uniprotkb:Q8WVR2|uniprotkb:Q9HCM5|uniprotkb:B4DPT0|uniprotkb:F8W964|uniprotkb:E9PD64|ensembl:ENSP00000452871|uniprotkb:Q6PI57 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tle3_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 3(gene name synonym)|uniprotkb:TLE3(gene name)|psi-mi:TLE3(display_short)|uniprotkb:KIAA1547(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001098662.1|refseq:NP_005069.2|refseq:NP_065959.1|refseq:NP_001269908.1|refseq:NP_001269909.1|refseq:NP_001269910.1|refseq:NP_001269911.1|ensembl:ENSG00000140332(gene)|ensembl:ENST00000558939(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q04726|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|reactome:R-HSA-9018519|dip:DIP-36666N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:lbsBYgdnyUWioqJ5euhotXA84Xg9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:Q04724 intact:EBI-25487926 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P67936 intact:EBI-25487926 intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P35241 intact:EBI-25487926 intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:75lzbINdL0deHtiWY7IwioSh5749606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P28289 intact:EBI-25487926 intact:EBI-2659631|uniprotkb:B2RB77|uniprotkb:Q5T7W3|uniprotkb:Q9BUF1|ensembl:ENSP00000259365|ensembl:ENSP00000378637|intact:EBI-10965302 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tmod1_human(display_long)|uniprotkb:Erythrocyte tropomodulin(gene name synonym)|uniprotkb:D9S57E(gene name synonym)|uniprotkb:TMOD(gene name synonym)|uniprotkb:TMOD1(gene name)|psi-mi:TMOD1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001159588.1|refseq:NP_003266.1|ensembl:ENST00000259365(transcript)|ensembl:ENST00000395211(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0070307"(lens fiber cell development)|interpro:IPR004934(Tropomodulin)|interpro:IPR030135|interpro:IPR032675|mint:P28289|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4Z8G|rcsb pdb:4Z94|reactome:R-HSA-390522|ensembl:ENSG00000136842(gene) - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:xbmnoh2E0cuP4ZYmnhlOo8QDnHw9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P14649 intact:EBI-25487926 intact:EBI-358570|ensembl:ENSP00000446643|ensembl:ENSP00000450385 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:myl6b_human(display_long)|uniprotkb:MYL6B(gene name)|psi-mi:MYL6B(display_short)|uniprotkb:MLC1SA(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym)|uniprotkb:Myosin light chain 1 slow-twitch muscle A isoform(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001186558.1|refseq:NP_002466.1|ensembl:ENSG00000196465(gene)|ensembl:ENST00000550443(transcript)|ensembl:ENST00000553066(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|reactome:R-HSA-445355 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:S0/S5hUxfyyve1JDMojIggOSBb89606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P13861 intact:EBI-25487926 intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P09493 intact:EBI-25487926 intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:P06396 intact:EBI-25487926 intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:O95684 intact:EBI-25487926 intact:EBI-1266334|uniprotkb:Q49AI0|uniprotkb:Q5R3F6|uniprotkb:Q96EW1|uniprotkb:A8K1D1|uniprotkb:B2R705|ensembl:ENSP00000355812 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cep43_human(display_long)|uniprotkb:CEP43(gene name)|psi-mi:CEP43(display_short)|uniprotkb:FGFR1 oncogene partner(gene name synonym)|uniprotkb:FGFR1OP(gene name synonym)|uniprotkb:FOP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_008976.1|refseq:NP_919410.1|ensembl:ENSG00000213066(gene)|ensembl:ENST00000366847(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR018993|rcsb pdb:2D68|reactome:R-HSA-1839117|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5655302|reactome:R-HSA-8854518 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:AcqOicx3UulQVfNzo6X0XyfExcc9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:O95613 intact:EBI-25487926 intact:EBI-530012|uniprotkb:O43152|uniprotkb:Q7Z7C9|intact:EBI-28971202|ensembl:ENSP00000352572 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:pcnt_human(display_long)|uniprotkb:Pericentrin-B(gene name synonym)|uniprotkb:Kendrin(gene name synonym)|uniprotkb:PCNT(gene name)|psi-mi:PCNT(display_short)|uniprotkb:KIAA0402(gene name synonym)|uniprotkb:PCNT2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSP00000352572|refseq:NP_006022.3|refseq:NP_001302458.1|ensembl:ENSG00000160299(gene)|ensembl:ENST00000359568(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR019528|interpro:IPR028745|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|dip:DIP-33829N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:8YHnOQE3b77ocsel2oAdsqvE+js9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:O75381 intact:EBI-25487926 intact:EBI-594898|uniprotkb:Q8WX51|uniprotkb:B2R7N1|uniprotkb:B3KML6|uniprotkb:B7Z1N2|intact:EBI-28983483|ensembl:ENSP00000349016 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:pex14_human(display_long)|uniprotkb:Peroxisomal membrane anchor protein PEX14(gene name synonym)|uniprotkb:PTS1 receptor-docking protein(gene name synonym)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_004556.1|refseq:XP_011539882.1|ensembl:ENSP00000349016|ensembl:ENSG00000142655(gene)|ensembl:ENST00000356607(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036250"(peroxisome transport along microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044721"(protein import into peroxisome matrix, substrate release)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|mint:O75381|rcsb pdb:2W84|rcsb pdb:2W85|rcsb pdb:4BXU|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9603798 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:9RXZ+bR4fRStCHsMQihNHBhqmCo9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:O60784 intact:EBI-25487926 intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:O60237 intact:EBI-25487926 intact:EBI-2558026|uniprotkb:B7ZMN6|uniprotkb:Q9HCB7|uniprotkb:Q5VUK2|uniprotkb:Q8N179|uniprotkb:Q9HCB8|uniprotkb:A8MYF5|uniprotkb:Q5T506|ensembl:ENSP00000476755|uniprotkb:Q2TAI8|uniprotkb:A0A0A0MS24 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:mypt2_human(display_long)|uniprotkb:PPP1R12B(gene name)|psi-mi:PPP1R12B(display_short)|uniprotkb:MYPT2(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001161330.1|refseq:NP_001184060.1|refseq:NP_002472.2|refseq:NP_115286.1|refseq:NP_115287.1|ensembl:ENSG00000077157(gene)|ensembl:ENST00000608999(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0031672"(A band)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_001161329.1|refseq:XP_016856841.1|refseq:XP_016856842.1|refseq:XP_016856843.1|refseq:NP_001317958.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:ykCXwp8fMkCrEkx6fqU5vrnTS549606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:O14908 intact:EBI-25487926 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037319 uniprotkb:O14639 intact:EBI-25487926 intact:EBI-487024|uniprotkb:A6NI16|uniprotkb:Q5T6N3|uniprotkb:Q5JVV1|uniprotkb:Q15039|uniprotkb:Q68CQ9|uniprotkb:Q9BUP1|uniprotkb:Q5T6N5|uniprotkb:B3KVH2|uniprotkb:Q5T6N2|uniprotkb:A6NJ06|uniprotkb:A8MXA9|uniprotkb:Q5JVV2|ensembl:ENSP00000277895 psi-mi:p0c6x7-pro_0000037319(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ablm1_human(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Actin-binding double zinc finger protein(gene name synonym)|uniprotkb:Limatin(gene name synonym)|uniprotkb:ABLIM1(gene name)|psi-mi:ABLIM1(display_short)|uniprotkb:ABLIM(gene name synonym)|uniprotkb:KIAA0059(gene name synonym)|uniprotkb:LIMAB1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377017|imex:IM-28441-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001003407.1|refseq:NP_002304.3|refseq:NP_006711.3|ensembl:ENSG00000099204(gene)|ensembl:ENST00000277895(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028448|interpro:IPR032402|interpro:IPR036886|mint:O14639|reactome:R-HSA-418885|go:"GO:0030032"(lamellipodium assembly)|refseq:NP_001309811.1|refseq:NP_001309821.1|refseq:NP_001309822.1|refseq:NP_001309825.1 - chain-seq-start:5302|chain-seq-end:5902 - figure legend:Table 2, no 8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:p7KzZyyr+yMS7ZiMTBx4VVZRzGc694009 rogid:Dsx3GrmdlsYUmQvuW59NfYF7MJg9606 rigid:Xdel/qiRSiAOMCtU0zsV2uc/LAg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037320 uniprotkb:Q9NXA8 intact:EBI-25487328 intact:EBI-6556144|uniprotkb:B4DFM4|uniprotkb:B4DYJ5|uniprotkb:F5H5Z9|uniprotkb:Q5T294|uniprotkb:Q5T295|uniprotkb:Q9Y6E6|ensembl:ENSP00000380509|ensembl:ENSP00000476228|ensembl:ENSP00000505086|ensembl:ENSP00000505496 psi-mi:p0c6x7-pro_0000037320(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sir5_human(display_long)|uniprotkb:SIRT5(gene name)|psi-mi:SIRT5(display_short)|uniprotkb:SIR2L5(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 5(gene name synonym)|uniprotkb:SIR2-like protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377088|imex:IM-28441-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001180196.1|refseq:NP_001229756.1|refseq:NP_036373.1|refseq:NP_112534.1|refseq:XP_005249025.1|ensembl:ENSG00000124523(gene)|ensembl:ENST00000397350(transcript)|ensembl:ENST00000606117(transcript)|ensembl:ENST00000680151(transcript)|ensembl:ENST00000680432(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010566"(regulation of ketone biosynthetic process)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0036046"(protein demalonylation)|go:"GO:0036047"(peptidyl-lysine demalonylation)|go:"GO:0036048"(protein desuccinylation)|go:"GO:0036049"(peptidyl-lysine desuccinylation)|go:"GO:0036054"(protein-malonyllysine demalonylase activity)|go:"GO:0036055"(protein-succinyllysine desuccinylase activity)|go:"GO:0061697"(protein-glutaryllysine deglutarylase activity)|go:"GO:0061698"(protein deglutarylation)|go:"GO:0070403"(NAD+ binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR027546|interpro:IPR029035|rcsb pdb:2B4Y|rcsb pdb:2NYR|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4G1C|rcsb pdb:4HDA|rcsb pdb:5BWL|rcsb pdb:5XHS|rcsb pdb:6ACE|rcsb pdb:6ACL|rcsb pdb:6ACO|rcsb pdb:6ACP|rcsb pdb:6EQS|rcsb pdb:6LJK|rcsb pdb:6LJM|rcsb pdb:6LJN|reactome:R-HSA-2151201 - chain-seq-start:5903|chain-seq-end:6429 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FPQjk4Qo6mt2gs5v5hPwe+xPyrI694009 rogid:w8a5w8pZghQpNpbgYCsuPIj+Sgo9606 rigid:rtKa3lWvR+XjpN9UOgzfzp4TWhg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037320 uniprotkb:Q96JN8 intact:EBI-25487328 intact:EBI-1053406|uniprotkb:Q6GPI8|uniprotkb:Q96IU9|uniprotkb:Q9H0B0|intact:EBI-2563327|intact:EBI-28979128|ensembl:ENSP00000382390|ensembl:ENSP00000500916 psi-mi:p0c6x7-pro_0000037320(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:neul4_human(display_long)|uniprotkb:NEURL4(gene name)|psi-mi:NEURL4(display_short)|uniprotkb:KIAA1787(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377088|imex:IM-28441-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001005408.1|refseq:NP_115818.2|ensembl:ENST00000315614|ensembl:ENSP00000319826|ensembl:ENSP00000382390|ensembl:ENSP00000500916|ensembl:ENST00000673081|ensembl:ENSP00000500667|ensembl:ENSG00000215041(gene)|ensembl:ENSG00000288301(gene)|ensembl:ENST00000399464(transcript)|ensembl:ENST00000671847(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006573(NEUZ)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037962|interpro:IPR043136|mint:Q96JN8|rcsb pdb:2E63 - chain-seq-start:5903|chain-seq-end:6429 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FPQjk4Qo6mt2gs5v5hPwe+xPyrI694009 rogid:lydZRBsnJDyAdaDjTe7gJVkxL149606 rigid:rtKa3lWvR+XjpN9UOgzfzp4TWhg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037320 uniprotkb:P12268 intact:EBI-25487328 intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584 psi-mi:p0c6x7-pro_0000037320(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377088|imex:IM-28441-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191 - chain-seq-start:5903|chain-seq-end:6429 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FPQjk4Qo6mt2gs5v5hPwe+xPyrI694009 rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606 rigid:rtKa3lWvR+XjpN9UOgzfzp4TWhg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037320 uniprotkb:P06280 intact:EBI-25487328 intact:EBI-2513305|ensembl:ENSP00000218516|uniprotkb:Q6LER7 psi-mi:p0c6x7-pro_0000037320(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:agal_human(display_long)|uniprotkb:GLA(gene name)|psi-mi:GLA(display_short)|uniprotkb:Alpha-D-galactoside galactohydrolase(gene name synonym)|uniprotkb:Alpha-D-galactosidase A(gene name synonym)|uniprotkb:Melibiase(gene name synonym)|uniprotkb:Galactosylgalactosylglucosylceramidase GLA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377088|imex:IM-28441-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) reactome:R-HSA-1660662|reactome:R-HSA-6798695|ensembl:ENSG00000102393(gene)|ensembl:ENST00000218516(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004557"(alpha-galactosidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016936"(galactoside binding)|go:"GO:0017041"(galactosylgalactosylglucosylceramidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046477"(glycosylceramide catabolic process)|go:"GO:0046479"(glycosphingolipid catabolic process)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0052692"(raffinose alpha-galactosidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000111(Glycoside hydrolase, clan GH-D)|interpro:IPR002241(Glycoside hydrolase, family 27)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR035373|rcsb pdb:1R46|rcsb pdb:1R47|rcsb pdb:3GXN|rcsb pdb:3GXP|rcsb pdb:3GXT|rcsb pdb:3HG2|rcsb pdb:3HG3|rcsb pdb:3HG4|rcsb pdb:3HG5|rcsb pdb:3LX9|rcsb pdb:3LXA|rcsb pdb:3LXB|rcsb pdb:3LXC|rcsb pdb:3S5Y|rcsb pdb:3S5Z|rcsb pdb:3TV8|rcsb pdb:4NXS|rcsb pdb:6IBK|rcsb pdb:6IBM|rcsb pdb:6IBR|rcsb pdb:6IBT|refseq:NP_000160.1 - chain-seq-start:5903|chain-seq-end:6429 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FPQjk4Qo6mt2gs5v5hPwe+xPyrI694009 rogid:en4+xuRp2k6kcAkvM2Bla9N3+189606 rigid:rtKa3lWvR+XjpN9UOgzfzp4TWhg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037320 uniprotkb:O95714 intact:EBI-25487328 intact:EBI-1058922|uniprotkb:Q86SV7|uniprotkb:Q86SV8|uniprotkb:Q86SV9|uniprotkb:Q86YY3|uniprotkb:Q86YY4|uniprotkb:Q86YY5|uniprotkb:Q86YY6|uniprotkb:Q86YY7|uniprotkb:Q86YY8|uniprotkb:Q86YY9|uniprotkb:Q86YZ0|uniprotkb:Q86YZ1|intact:EBI-1104961|intact:EBI-28977852|ensembl:ENSP00000261609 psi-mi:p0c6x7-pro_0000037320(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:herc2_human(display_long)|uniprotkb:HERC2(gene name)|psi-mi:HERC2(display_short)|uniprotkb:HECT domain and RCC1-like domain-containing protein 2(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HERC2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377088|imex:IM-28441-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSP00000261609|refseq:NP_004658.3|ensembl:ENSG00000128731(gene)|ensembl:ENST00000261609(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032183"(SUMO binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR000569(HECT)|interpro:IPR001199(Cytochrome b5)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR006624(Beta-propeller repeat TECPR)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR010606(Mib-herc2)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR021097|interpro:IPR035983|interpro:IPR036400|interpro:IPR037252|interpro:IPR037976|interpro:IPR041987|interpro:IPR043145|mint:O95714|rcsb pdb:2KEO|go:"GO:0031625"(ubiquitin protein ligase binding)|rcsb pdb:3KCI|rcsb pdb:4L1M|rcsb pdb:6WW4|reactome:R-HSA-3108214|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|reactome:R-HSA-983168|rcsb pdb:6WW3|dip:DIP-37632N - chain-seq-start:5903|chain-seq-end:6429 - figure legend:Table 2, no 9|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FPQjk4Qo6mt2gs5v5hPwe+xPyrI694009 rogid:ejMTmb0F9pM7zfHbRscV1rIRgSw9606 rigid:rtKa3lWvR+XjpN9UOgzfzp4TWhg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037321 uniprotkb:P62330 intact:EBI-25487301 intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2 psi-mi:p0c6x7-pro_0000037321(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377105|imex:IM-28441-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N - chain-seq-start:6430|chain-seq-end:6775 - figure legend:Table 2, no 10|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:2/KeRA/+BMPlzdh567VMVEXj9Tc694009 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606 rigid:n8Qbn/JaNnhizEaYJJ++3PYLYsM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037322 uniprotkb:Q9Y2S7 intact:EBI-25487235 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377113|imex:IM-28441-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - chain-seq-start:6776|chain-seq-end:7073 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:JTzbH8OAMaz0EuYV/dsdzygaIVM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037322 uniprotkb:Q9UKF6 intact:EBI-25487235 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377113|imex:IM-28441-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N - chain-seq-start:6776|chain-seq-end:7073 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rigid:JTzbH8OAMaz0EuYV/dsdzygaIVM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037322 uniprotkb:Q8TEM1 intact:EBI-25487235 intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508 psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377113|imex:IM-28441-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690 - chain-seq-start:6776|chain-seq-end:7073 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009 rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606 rigid:JTzbH8OAMaz0EuYV/dsdzygaIVM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037322 uniprotkb:Q8IUD2 intact:EBI-25487235 intact:EBI-1044755|uniprotkb:Q6NVK2|uniprotkb:Q8IUD3|uniprotkb:Q8IUD4|uniprotkb:Q8IUD5|uniprotkb:Q8NAS1|uniprotkb:Q9NXN5|uniprotkb:Q9UIK7|uniprotkb:Q9UPS1|intact:EBI-3645200|uniprotkb:A7E295|ensembl:ENSP00000354158|ensembl:ENSP00000468263|uniprotkb:D3DUP7|uniprotkb:D3DUP8|uniprotkb:A2RU77 psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:rb6i2_human(display_long)|uniprotkb:Rab6-interacting protein 2(gene name synonym)|uniprotkb:ERC1(gene name)|psi-mi:ERC1(display_short)|uniprotkb:ELKS(gene name synonym)|uniprotkb:KIAA1081(gene name synonym)|uniprotkb:RAB6IP2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377113|imex:IM-28441-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_829883.1|refseq:NP_829884.1|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0015031"(protein transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0007275"(multicellular organism development)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR019018|interpro:IPR019323|interpro:IPR037245|ensembl:ENSG00000082805(gene)|ensembl:ENST00000360905(transcript)|ensembl:ENST00000589028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|refseq:XP_016874553.1|refseq:XP_016874556.1|refseq:XP_011519243.1 - chain-seq-start:6776|chain-seq-end:7073 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009 rogid:0W5DM0QbKuWdMW4T+pJKPT7pKgA9606 rigid:JTzbH8OAMaz0EuYV/dsdzygaIVM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037322 uniprotkb:Q5SVZ6 intact:EBI-25487235 intact:EBI-2555834|uniprotkb:Q7Z3Q4|ensembl:ENSP00000352920|ensembl:ENSP00000362427|ensembl:ENSP00000482579|ensembl:ENSP00000496876|uniprotkb:D3DPR7 psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:zmym1_human(display_long)|uniprotkb:ZMYM1(gene name)|psi-mi:ZMYM1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377113|imex:IM-28441-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_079048.3|ensembl:ENSG00000197056(gene)|ensembl:ENST00000359858(transcript)|ensembl:ENST00000373330(transcript)|ensembl:ENST00000611874(transcript)|ensembl:ENST00000650449(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008906(HAT dimerisation)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025398|mint:Q5SVZ6|refseq:NP_001306884.1|ensembl:ENSP00000352920|ensembl:ENSP00000362427|ensembl:ENSP00000482579|ensembl:ENSP00000496876|refseq:NP_001276017.1|refseq:NP_001276018.1|refseq:NP_001276019.1 - chain-seq-start:6776|chain-seq-end:7073 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009 rogid:Mi/JhPhavQr3W2r/4xHAGfYjMWE9606 rigid:JTzbH8OAMaz0EuYV/dsdzygaIVM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037322 uniprotkb:Q567U6 intact:EBI-25487235 intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477 psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377113|imex:IM-28441-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3 - chain-seq-start:6776|chain-seq-end:7073 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009 rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606 rigid:JTzbH8OAMaz0EuYV/dsdzygaIVM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037322 uniprotkb:P28838 intact:EBI-25487235 intact:EBI-2339312|uniprotkb:Q6IAM6|uniprotkb:Q6P0L6|uniprotkb:Q9UQE3|uniprotkb:B3KMQ3|ensembl:ENSP00000226299|ensembl:ENSP00000481000 psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ampl_human(display_long)|uniprotkb:LAP3(gene name)|psi-mi:LAP3(display_short)|uniprotkb:LAPEP(gene name synonym)|uniprotkb:PEPS(gene name synonym)|uniprotkb:Leucyl aminopeptidase(gene name synonym)|uniprotkb:Leucine aminopeptidase 3(gene name synonym)|uniprotkb:Proline aminopeptidase(gene name synonym)|uniprotkb:Prolyl aminopeptidase(gene name synonym)|uniprotkb:Peptidase S(gene name synonym)|uniprotkb:Cysteinylglycine-S-conjugate dipeptidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377113|imex:IM-28441-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_056991.2|ensembl:ENSG00000002549(gene)|ensembl:ENST00000226299(transcript)|ensembl:ENST00000618908(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030496"(midbody)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000819(Peptidase M17, leucyl aminopeptidase, C-terminal)|interpro:IPR008283(Peptidase M17, leucyl aminopeptidase, N-terminal)|interpro:IPR011356(Peptidase M17, leucyl aminopeptidase)|interpro:IPR023042|interpro:IPR043472|mint:P28838 - chain-seq-start:6776|chain-seq-end:7073 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009 rogid:BGEwM09Jm/Nn1CwI+QguAqIwGzw9606 rigid:JTzbH8OAMaz0EuYV/dsdzygaIVM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037322 uniprotkb:O60232 intact:EBI-25487235 intact:EBI-741415|ensembl:ENSP00000312318 psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377113|imex:IM-28441-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ - chain-seq-start:6776|chain-seq-end:7073 - figure legend:Table 2, no 11|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009 rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606 rigid:JTzbH8OAMaz0EuYV/dsdzygaIVM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q13347 intact:EBI-25474098 intact:EBI-354047|intact:EBI-11759480|ensembl:ENSP00000504034|ensembl:ENSP00000504061|ensembl:ENSP00000502867|ensembl:ENSP00000503348|ensembl:ENSP00000503539 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3i_human(display_long)|uniprotkb:EIF3I(gene name)|psi-mi:EIF3I(display_short)|uniprotkb:TRIP1(gene name synonym)|uniprotkb:EIF3S2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_003748.1|ensembl:ENST00000676801(transcript)|ensembl:ENST00000677202(transcript)|ensembl:ENST00000677701(transcript)|ensembl:ENST00000677711(transcript)|ensembl:ENST00000677760(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|ensembl:ENSG00000084623(gene)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q13347|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31116N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:fogC6nSNmIynV2ziHZboT9laA3M9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:P55884 intact:EBI-25474098 intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|ensembl:ENSP00000354125|ensembl:ENSP00000380206 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001032360.1|refseq:NP_003742.2|refseq:XP_011513901.1|refseq:XP_011513902.1|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|ensembl:ENSG00000106263(gene)|ensembl:ENST00000360876(transcript)|ensembl:ENST00000397011(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_016868241.1|dip:DIP-31113N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O15371 intact:EBI-25474098 intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q9Y262 intact:EBI-25474098 intact:EBI-373519|uniprotkb:Q53HQ1|uniprotkb:Q53HT4|uniprotkb:Q5QTR1|uniprotkb:Q5TI15|uniprotkb:Q6ICD2|uniprotkb:B2RDG6|uniprotkb:B4DYB2|uniprotkb:G8JLH4|intact:EBI-10970119|ensembl:ENSP00000485663|ensembl:ENSP00000499067 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3l_human(display_long)|uniprotkb:EIF3L(gene name)|psi-mi:EIF3L(display_short)|uniprotkb:HSPC021(orf name)|uniprotkb:HSPC025(orf name)|uniprotkb:EIF3S6IP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6-interacting protein(gene name synonym)|uniprotkb:MSTP005(orf name)|uniprotkb:EIF3EIP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit E-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_057175.1|refseq:NP_001229852.1|dip:DIP-31172N|ensembl:ENSG00000100129(gene)|ensembl:ENST00000624234(transcript)|ensembl:ENST00000652021(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|mint:Q9Y262|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:C9ES0WpTdEHUkjWeZK/SoDP/dAo9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q9UBQ5 intact:EBI-25474098 intact:EBI-354344|uniprotkb:Q96IQ0|uniprotkb:Q9Y6D1|intact:EBI-2339187|uniprotkb:A8K0I9|ensembl:ENSP00000248342|ensembl:ENSP00000489438|uniprotkb:B7ZAM9 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3k_human(display_long)|uniprotkb:MSTP001(orf name)|uniprotkb:PTD001(orf name)|uniprotkb:HSPC029(orf name)|uniprotkb:EIF3K(gene name)|psi-mi:EIF3K(display_short)|uniprotkb:ARG134(orf name)|uniprotkb:EIF3S12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)|uniprotkb:eIF-3 p28(gene name synonym)|uniprotkb:Muscle-specific gene M9 protein(gene name synonym)|uniprotkb:PLAC-24(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_037366.1|ensembl:ENSG00000282986(gene)|ensembl:ENST00000248342(transcript)|ensembl:ENST00000635567(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000178982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9UBQ5|rcsb pdb:1RZ4|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32880N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:sle5eYxV0F37AzixzoNY4Jm6Loo9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q9C037 intact:EBI-25474098 intact:EBI-4307604|uniprotkb:Q9C036|uniprotkb:Q96F06|uniprotkb:A4D298|uniprotkb:Q75MK1|ensembl:ENSP00000348216 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:trim4_human(display_long)|uniprotkb:TRIM4(gene name)|psi-mi:TRIM4(display_short)|uniprotkb:RING-type E3 ubiquitin transferase TRIM4(gene name synonym)|uniprotkb:Tripartite motif-containing protein 4(gene name synonym)|uniprotkb:RNF87(gene name synonym)|uniprotkb:RING finger protein 87(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_148977.2|refseq:NP_149082.1|ensembl:ENST00000355947(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000146833(gene)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035829|interpro:IPR043136|reactome:R-HSA-983168 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:x0Ig4/YAD4KeGptdNhCbmNxsbas9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q99613 intact:EBI-25474098 intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q86UK7 intact:EBI-25474098 intact:EBI-719433|uniprotkb:Q8IW49|uniprotkb:Q8N3D9|uniprotkb:Q96FG3|uniprotkb:Q9H7J3 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zn598_human(display_long)|uniprotkb:ZNF598(gene name)|psi-mi:ZNF598(display_short)|uniprotkb:Zinc finger protein 598(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0003723"(RNA binding)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072344"(rescue of stalled ribosome)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_835461.2|interpro:IPR041888|interpro:IPR044288 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:0tZK9I7W7oOVjz125Iloe6kjdj89606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q7L2H7 intact:EBI-25474098 intact:EBI-353901|intact:EBI-4289539|intact:EBI-715219|uniprotkb:Q2F836|uniprotkb:Q53HL6|uniprotkb:Q9BXW1|uniprotkb:O60735|uniprotkb:A8K7X4|intact:EBI-2559366|ensembl:ENSP00000436049|intact:EBI-373200|uniprotkb:B4E2Q4 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3m_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)|uniprotkb:HFLB5(gene name synonym)|uniprotkb:PCID1(gene name synonym)|uniprotkb:PCI domain-containing protein 1(gene name synonym)|uniprotkb:Fetal lung protein B5(gene name synonym)|uniprotkb:GA17(orf name)|uniprotkb:PNAS-125(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_006351.2|refseq:NP_001294858.1|ensembl:ENSG00000149100(gene)|ensembl:ENST00000531120(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|mint:Q7L2H7|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31256N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:siTfTDezqWL90pw6xG3xUKfY9n49606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q6Y7W6 intact:EBI-25474098 intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q6NUN9 intact:EBI-25474098 intact:EBI-3862525|uniprotkb:A8K6Z9|uniprotkb:Q6ZRF9|ensembl:ENSP00000345140 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:zn746_human(display_long)|uniprotkb:PARIS(gene name synonym)|uniprotkb:ZNF746(gene name)|psi-mi:ZNF746(display_short)|uniprotkb:Parkin-interacting substrate(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001156946.1|refseq:NP_689770.3|ensembl:ENSG00000181220(gene)|ensembl:ENST00000340622(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022137|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:MlT4SO+v9Ahg4HY5x1b2QFCCGgc9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q14152 intact:EBI-25474098 intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:P60228 intact:EBI-25474098 intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:s09LicCa0mb9WwO7esZvVdvUonY9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:P52306 intact:EBI-25474098 intact:EBI-746389|uniprotkb:Q9BUW9|ensembl:ENSP00000386153|intact:EBI-3184182|uniprotkb:G5E9P9|uniprotkb:Q499L7|uniprotkb:Q4KMV2|uniprotkb:Q9BUX6|uniprotkb:Q9NYM2|uniprotkb:Q9NZA8|intact:EBI-4397492|uniprotkb:E9PH06|uniprotkb:Q4QQI8|intact:EBI-11106358 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gds1_human(display_long)|uniprotkb:RAP1GDS1(gene name)|psi-mi:RAP1GDS1(display_short)|uniprotkb:Exchange factor smgGDS(gene name synonym)|uniprotkb:SMG GDS protein(gene name synonym)|uniprotkb:SMG P21 stimulatory GDP/GTP exchange protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_066982.3|refseq:NP_001093898.1|ensembl:ENSG00000138698(gene)|ensembl:ENST00000408927(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040144|rcsb pdb:5XGC|rcsb pdb:5ZHX|reactome:R-HSA-9013419|reactome:R-HSA-9013425|refseq:NP_001093896.1|refseq:NP_001093897.1|refseq:NP_001093899.1|refseq:NP_001093900.1|dip:DIP-61080N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:CBqwhiENmk65uN7XyiVVYZ+W6R09606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O75822 intact:EBI-25474098 intact:EBI-366647|uniprotkb:Q9BUD2|uniprotkb:Q9H8Q2|uniprotkb:Q9UI65|ensembl:ENSP00000261868|uniprotkb:B4DUI3|uniprotkb:F5H425 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3j_human(display_long)|uniprotkb:EIF3J(gene name)|psi-mi:EIF3J(display_short)|uniprotkb:PRO0391(orf name)|uniprotkb:EIF3S1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 1(gene name synonym)|uniprotkb:eIF-3-alpha(gene name synonym)|uniprotkb:eIF3 p35(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001271264.1|refseq:NP_001271265.1|refseq:NP_003749.2|ensembl:ENSG00000104131(gene)|ensembl:ENST00000261868(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|mint:O75822|rcsb pdb:2KRB|rcsb pdb:3BPJ|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31117N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:dJ+uqlLn3RH30Rw3COnJ+/nkk+I9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O75821 intact:EBI-25474098 intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O60573 intact:EBI-25474098 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O15372 intact:EBI-25474098 intact:EBI-709735|ensembl:ENSP00000429931 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O00303 intact:EBI-25474098 intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377128|imex:IM-28441-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N - chain-seq-start:181|chain-seq-end:818 - figure legend:Table 2, no 12|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606 rigid:zzZQYfiOYuw/XEIs7nHBTMZ6n/M false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9NWU2 intact:EBI-25488721 intact:EBI-1051077|uniprotkb:Q8N5M5|uniprotkb:E1P5I3|ensembl:ENSP00000266069 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gid8_human(display_long)|uniprotkb:GID8(gene name)|psi-mi:GID8(display_short)|uniprotkb:C20orf11(gene name synonym)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym)|uniprotkb:TWA1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377154|imex:IM-28441-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_060366.1|ensembl:ENSG00000101193(gene)|ensembl:ENST00000266069(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9NWU2|rcsb pdb:7NSC - chain-seq-start:2741|chain-seq-end:3240 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:P0HsK72KT6OPKKw7lVSJ/FiY4CU9606 rigid:OWIfX453xiEKDPdPEz60jn8EuZc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9H871 intact:EBI-25488721 intact:EBI-2797992|uniprotkb:Q6NTF0|uniprotkb:Q9H9H2|uniprotkb:Q9H6W5|uniprotkb:D6W5M6|ensembl:ENSP00000283632 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rmd5a_human(display_long)|uniprotkb:RMND5A(gene name)|psi-mi:RMND5A(display_short)|uniprotkb:P44CTLH(gene name synonym)|uniprotkb:Protein RMD5 homolog A(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377154|imex:IM-28441-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_073617.1|ensembl:ENSG00000153561(gene)|ensembl:ENST00000283632(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR037680|interpro:IPR044063|mint:Q9H871 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:+wLGFpC1YJ1y6PVi15799YxByKI9606 rigid:OWIfX453xiEKDPdPEz60jn8EuZc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9H7D7 intact:EBI-25488721 intact:EBI-1046864|uniprotkb:A0MNN3|uniprotkb:Q4G100|uniprotkb:Q59EC4|uniprotkb:Q5GLZ9|uniprotkb:Q86UY4|uniprotkb:Q9H3C2|ensembl:ENSP00000504428|intact:EBI-1642504 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wdr26_human(display_long)|uniprotkb:CUL4- and DDB1-associated WDR protein 2(gene name synonym)|uniprotkb:Myocardial ischemic preconditioning up-regulated protein 2(gene name synonym)|uniprotkb:WDR26(gene name)|psi-mi:WDR26(display_short)|uniprotkb:CDW2(gene name synonym)|uniprotkb:MIP2(gene name synonym)|uniprotkb:PRO0852(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377154|imex:IM-28441-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9H7D7|ensembl:ENSG00000162923(gene)|ensembl:ENST00000678917(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|refseq:NP_001108585.2|refseq:NP_079436.4 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:HRA6f68aldUqB1rVa7uM9srSyR49606 rigid:OWIfX453xiEKDPdPEz60jn8EuZc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q96S59 intact:EBI-25488721 intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377154|imex:IM-28441-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 rigid:OWIfX453xiEKDPdPEz60jn8EuZc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q7L5Y9 intact:EBI-25488721 intact:EBI-10984762|ensembl:ENSP00000302830|uniprotkb:O95285|uniprotkb:Q5JB54|uniprotkb:Q6ZRD6|uniprotkb:Q9NW84|uniprotkb:Q9H9Z4|uniprotkb:Q9BQ11|uniprotkb:Q9H9V6 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:maea_human(display_long)|uniprotkb:MAEA(gene name)|psi-mi:MAEA(display_short)|uniprotkb:Cell proliferation-inducing gene 5 protein(gene name synonym)|uniprotkb:EMP(gene name synonym)|uniprotkb:Erythroblast macrophage protein(gene name synonym)|uniprotkb:Human lung cancer oncogene 10 protein(gene name synonym)|uniprotkb:Macrophage erythroblast attacher(gene name synonym)|uniprotkb:P44EMLP(gene name synonym)|uniprotkb:HLC10(orf name)|uniprotkb:PIG5(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377154|imex:IM-28441-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001017405.1|refseq:NP_001284360.1|refseq:NP_005873.2|ensembl:ENSG00000090316(gene)|ensembl:ENST00000303400(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR027714|interpro:IPR044063|mint:Q7L5Y9 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:8eoZgqL1bgRlGgQ3YiJDejdFWtk9606 rigid:OWIfX453xiEKDPdPEz60jn8EuZc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q6VN20 intact:EBI-25488721 intact:EBI-310569|intact:EBI-1056526|uniprotkb:A4FTY2|uniprotkb:Q9P264|intact:EBI-10984753|ensembl:ENSP00000316589|uniprotkb:B4DID0|uniprotkb:B4DQH9|uniprotkb:E7EW27 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rbp10_human(display_long)|uniprotkb:RANBP10(gene name)|psi-mi:RANBP10(display_short)|uniprotkb:KIAA1464(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377154|imex:IM-28441-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_065901.1|refseq:NP_001307167.1|refseq:NP_001307168.1|refseq:NP_001307169.1|ensembl:ENSG00000141084(gene)|ensembl:ENST00000317506(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q6VN20|reactome:R-HSA-8851805 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:DaNPLQf0T/+lsKrL+uhGtWXG0pI9606 rigid:OWIfX453xiEKDPdPEz60jn8EuZc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:P62699 intact:EBI-25488721 intact:EBI-11721624|uniprotkb:D6W568|uniprotkb:Q65Z97|uniprotkb:Q8R174|uniprotkb:Q9D6M1|uniprotkb:Q9UMX7|uniprotkb:Q9Y3C9|ensembl:ENSP00000261353|ensembl:ENSP00000368834|ensembl:ENSP00000368835|ensembl:ENSP00000383974|ensembl:ENSP00000385278 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ypel5_human(display_long)|uniprotkb:YPEL5(gene name)|psi-mi:YPEL5(display_short)|uniprotkb:CGI-127(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377154|imex:IM-28441-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001120871.1|refseq:NP_001120872.1|refseq:NP_001120873.1|refseq:NP_057145.1|ensembl:ENSG00000119801(gene)|ensembl:ENST00000261353(transcript)|ensembl:ENST00000379519(transcript)|ensembl:ENST00000379520(transcript)|ensembl:ENST00000402003(transcript)|ensembl:ENST00000402708(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030496"(midbody)|go:"GO:0046872"(metal ion binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034751|interpro:IPR039058|mint:P62699|reactome:R-HSA-6798695|refseq:XP_016859807.1|refseq:XP_016859808.1|refseq:XP_016859809.1|refseq:XP_016859810.1|refseq:XP_016859811.1 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:ZpDZwTkWSDPONRLnApZ8fKl/NHk9606 rigid:OWIfX453xiEKDPdPEz60jn8EuZc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:P14735 intact:EBI-25488721 intact:EBI-2556886|uniprotkb:Q5T5N2|uniprotkb:D3DR35|ensembl:ENSP00000265986|uniprotkb:B2R721|uniprotkb:B7ZAU2 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ide_human(display_long)|uniprotkb:IDE(gene name)|psi-mi:IDE(display_short)|uniprotkb:Insulin protease(gene name synonym)|uniprotkb:Insulysin(gene name synonym)|uniprotkb:Abeta-degrading protease(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377154|imex:IM-28441-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_004960.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010815"(bradykinin catabolic process)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031626"(beta-endorphin binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000119912(gene)|ensembl:ENST00000265986(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0043559"(insulin binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901142"(insulin metabolic process)|go:"GO:1901143"(insulin catabolic process)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR032632|mint:P14735|rcsb pdb:2G47|rcsb pdb:2G48|rcsb pdb:2G49|rcsb pdb:2G54|rcsb pdb:2G56|rcsb pdb:2JBU|rcsb pdb:2JG4|rcsb pdb:2WBY|rcsb pdb:2WC0|rcsb pdb:2WK3|rcsb pdb:2YPU|rcsb pdb:3CWW|rcsb pdb:3E4A|rcsb pdb:3E4Z|rcsb pdb:3E50|rcsb pdb:3H44|rcsb pdb:3N56|rcsb pdb:3N57|rcsb pdb:3OFI|rcsb pdb:3QZ2|rcsb pdb:4DTT|rcsb pdb:4DWK|rcsb pdb:4GS8|rcsb pdb:4GSC|rcsb pdb:4GSF|rcsb pdb:4IFH|rcsb pdb:4IOF|rcsb pdb:4LTE|rcsb pdb:4M1C|rcsb pdb:4NXO|rcsb pdb:4PES|rcsb pdb:4PF7|rcsb pdb:4PF9|rcsb pdb:4PFC|rcsb pdb:4QIA|rcsb pdb:4RAL|rcsb pdb:4RE9|rcsb pdb:5CJO|rcsb pdb:3HGZ|rcsb pdb:5UOE|rcsb pdb:5WOB|rcsb pdb:6B3Q|rcsb pdb:6B70|rcsb pdb:6B7Y|rcsb pdb:6BF6|rcsb pdb:6BF7|rcsb pdb:6BF8|rcsb pdb:6BF9|rcsb pdb:6BFC|rcsb pdb:6BYZ|rcsb pdb:6EDS|rcsb pdb:6MQ3|reactome:R-HSA-5689880|reactome:R-HSA-9033241|rcsb pdb:6B7Z|refseq:NP_001159418.1|dip:DIP-55771N - chain-seq-start:2741|chain-seq-end:3240 - figure legend:Table 2, no 13|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:dwngN3kUOExC5qapSgF01YhBNAM9606 rigid:OWIfX453xiEKDPdPEz60jn8EuZc false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037312 uniprotkb:P07203 intact:EBI-25487250 intact:EBI-7209024|uniprotkb:E9PAS1|ensembl:ENSP00000407375|uniprotkb:Q7Z5H1|uniprotkb:Q9BW12|intact:UNK-5370138 psi-mi:p0c6x7-pro_0000037312(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gpx1_human(display_long)|uniprotkb:GPX1(gene name)|psi-mi:GPX1(display_short)|uniprotkb:Cellular glutathione peroxidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377169|imex:IM-28441-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) refseq:NP_000572.2|ensembl:ENSG00000233276(gene)|ensembl:ENST00000419783(transcript)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001885"(endothelial cell development)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009609"(response to symbiotic bacterium)|go:"GO:0009650"(UV protection)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042311"(vasodilation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060047"(heart contraction)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902905"(positive regulation of supramolecular fiber organization)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|mint:P07203|rcsb pdb:2F8A|reactome:R-HSA-2142688|reactome:R-HSA-2142712|reactome:R-HSA-2142770|reactome:R-HSA-3299685|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0061136"(regulation of proteasomal protein catabolic process) - chain-seq-start:3241|chain-seq-end:3546 comment:mint|comment:homomint|function:Protects the hemoglobin in erythrocytes from oxidative breakdown figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:6LbRC/jITHtqNPZLpKst/+pNdOQ694009 rogid:1/6I8LekGumy+rLlaLFqCbl1gV09606 rigid:l6NLvulCXpzNYwn8G8fGO3a4/ZA false strep tag:?-?|mutation:145-145 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037312 uniprotkb:Q9NXH9 intact:EBI-25487250 intact:EBI-748900|uniprotkb:O76103|uniprotkb:Q548Y5|uniprotkb:Q8WVA6|ensembl:ENSP00000350352|ensembl:ENSP00000416149|ensembl:ENSP00000466967 psi-mi:p0c6x7-pro_0000037312(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:trm1_human(display_long)|uniprotkb:"tRNA(guanine-26,N(2)-N(2)) methyltransferase"(gene name synonym)|uniprotkb:tRNA 2,2-dimethylguanosine-26 methyltransferase(gene name synonym)|uniprotkb:"tRNA(m(2,2)G26)dimethyltransferase"(gene name synonym)|uniprotkb:TRMT1(gene name)|psi-mi:TRMT1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377169|imex:IM-28441-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) refseq:NP_001129507.1|refseq:NP_001136026.1|refseq:NP_060192.1|refseq:XP_016882433.1|refseq:XP_016882434.1|ensembl:ENSG00000104907(gene)|ensembl:ENST00000357720(transcript)|ensembl:ENST00000437766(transcript)|ensembl:ENST00000592062(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002940"(tRNA N2-guanine methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0004809"("tRNA (guanine-N2-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002905(N2,N2-dimethylguanosine tRNA methyltransferase)|interpro:IPR029063|interpro:IPR036855|interpro:IPR042296|mint:Q9NXH9|reactome:R-HSA-6782315 - chain-seq-start:3241|chain-seq-end:3546 - figure legend:Table 2, no 14|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:6LbRC/jITHtqNPZLpKst/+pNdOQ694009 rogid:ty0oTgEETLwZTnDb1RFHkrkCQsU9606 rigid:l6NLvulCXpzNYwn8G8fGO3a4/ZA false strep tag:?-?|mutation:145-145 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037313 uniprotkb:Q99720 intact:EBI-25487192 intact:EBI-3248663|ensembl:ENSP00000277010|uniprotkb:O00673|uniprotkb:Q2TSD1|uniprotkb:Q7Z653|uniprotkb:Q153Z1|uniprotkb:Q53GN2|uniprotkb:Q9NYX0|uniprotkb:O00725|uniprotkb:Q8N7H3|uniprotkb:Q0Z9W6|uniprotkb:D3DRM7 psi-mi:p0c6x7-pro_0000037313(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:sgmr1_human(display_long)|uniprotkb:SIGMAR1(gene name)|psi-mi:SIGMAR1(display_short)|uniprotkb:OPRS1(gene name synonym)|uniprotkb:SRBP(gene name synonym)|uniprotkb:Aging-associated gene 8 protein(gene name synonym)|uniprotkb:SR31747-binding protein(gene name synonym)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:AAG8(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377180|imex:IM-28441-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) ensembl:ENSG00000147955(gene)|ensembl:ENST00000277010(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)|mint:Q99720|rcsb pdb:5HK1|rcsb pdb:5HK2|rcsb pdb:6DJZ|rcsb pdb:6DK0|rcsb pdb:6DK1|reactome:R-HSA-9679191|refseq:NP_005857.1|refseq:NP_671513.1|refseq:NP_001269134.1|refseq:NP_001269135.1|refseq:NP_001269136.1|refseq:NP_001269137.1|refseq:NP_001269138.1|dip:DIP-61974N - chain-seq-start:3547|chain-seq-end:3836 - figure legend:Table 2, no 15|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:gj8dp2I2Ya5s1l4ssgeZJvDPfVM694009 rogid:iEc1O6PXikkaE/0zk0A5Z7fMIZ49606 rigid:2sSDum97JBldJ1xK74+oyeQ+tdM false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q9Y3D7 intact:EBI-25487672 intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene) - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q9NYP7 intact:EBI-25487672 intact:EBI-11037623|uniprotkb:Q5TGH5|uniprotkb:F6SH78|uniprotkb:B4DZJ2|uniprotkb:Q59EL3|uniprotkb:Q8NCG4|uniprotkb:Q7L2S5|uniprotkb:Q9UI22|uniprotkb:Q6NXE7|ensembl:ENSP00000306640 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:elov5_human(display_long)|uniprotkb:Very long chain 3-ketoacyl-CoA synthase 5(gene name synonym)|uniprotkb:Very long chain 3-oxoacyl-CoA synthase 5(gene name synonym)|uniprotkb:PRO0530(orf name)|uniprotkb:ELOVL5(gene name)|psi-mi:ELOVL5(display_short)|uniprotkb:3-keto acyl-CoA synthase ELOVL5(gene name synonym)|uniprotkb:ELOVL fatty acid elongase 5(gene name synonym)|uniprotkb:ELOVL2(gene name synonym)|uniprotkb:Fatty acid elongase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001229757.1|refseq:NP_001229759.1|refseq:NP_001229760.1|refseq:NP_001288785.1|refseq:NP_068586.1|ensembl:ENSG00000012660(gene)|ensembl:ENST00000304434(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0016020"(membrane)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0097447"(dendritic tree)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR033677|reactome:R-HSA-2046105|reactome:R-HSA-2046106|reactome:R-HSA-75876 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:7kQZS7mYa5eCSOslo4+z9nwtxxk9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q9H7Z7 intact:EBI-25487672 intact:EBI-681645|uniprotkb:Q53EW9|uniprotkb:Q5SYV6|uniprotkb:Q96GI0|uniprotkb:Q96GL2|ensembl:ENSP00000345341 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pges2_human(display_long)|uniprotkb:Microsomal prostaglandin E synthase 2(gene name synonym)|uniprotkb:PTGES2(gene name)|psi-mi:PTGES2(display_short)|uniprotkb:PGES2(gene name synonym)|uniprotkb:C9orf15(gene name synonym)|uniprotkb:Membrane-associated prostaglandin E synthase-2(gene name synonym)|uniprotkb:"Prostaglandin-H(2) E-isomerase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001243264.1|refseq:NP_079348.1|refseq:NP_945176.1|ensembl:ENSG00000148334(gene)|ensembl:ENST00000338961(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016829"(lyase activity)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0020037"(heme binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036134"(12-hydroxyheptadecatrienoic acid synthase activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050220"(prostaglandin-E synthase activity)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034334|interpro:IPR034335|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:Q9H7Z7|reactome:R-HSA-2162123|reactome:R-HSA-6798695 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:DFALgQTHlFSBHZUZBKTJNxxSqjk9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q9BQE4 intact:EBI-25487672 intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process) - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q96KC8 intact:EBI-25487672 intact:EBI-296550|uniprotkb:Q5VX89|uniprotkb:Q9H6B8|uniprotkb:B0YIZ8|ensembl:ENSP00000366179 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dnjc1_human(display_long)|uniprotkb:DNAJC1(gene name)|psi-mi:DNAJC1(display_short)|uniprotkb:DnaJ protein homolog MTJ1(gene name synonym)|uniprotkb:HTJ1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_071760.2|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR017884|interpro:IPR017930|interpro:IPR018253|interpro:IPR036869|rcsb pdb:2CQQ|rcsb pdb:2CQR|ensembl:ENSG00000136770(gene)|ensembl:ENST00000376980(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051087"(chaperone binding) - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:rYAqjvnyqhi9qp+KGQBZ2wjzV4Y9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q96ER9 intact:EBI-25487672 intact:EBI-11926384|ensembl:ENSP00000379047|uniprotkb:Q9HA01 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mitok_human(display_long)|uniprotkb:CCDC51(gene name)|psi-mi:CCDC51(display_short)|uniprotkb:Coiled-coil domain-containing protein 51(gene name synonym)|uniprotkb:MITOK(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000164051(gene)|ensembl:ENST00000395694(transcript)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0062156"(mitochondrial ATP-gated potassium channel activity)|go:"GO:0062157"(mitochondrial ATP-gated potassium channel complex)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR037660|refseq:NP_001243893.1|refseq:NP_001243894.1|refseq:NP_001243895.1|refseq:NP_001243896.1|refseq:NP_001243897.1|refseq:NP_001243898.1|refseq:NP_078937.3 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:J1EUSmdcwzWhKwXNVhzPEu8YxAA9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q96A26 intact:EBI-25487672 intact:EBI-6123466|uniprotkb:Q9NRN6|uniprotkb:Q9UJX8|ensembl:ENSP00000419088 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:f162a_human(display_long)|uniprotkb:FAM162A(gene name)|psi-mi:FAM162A(display_short)|uniprotkb:C3orf28(gene name synonym)|uniprotkb:E2IG5(gene name synonym)|uniprotkb:E2-induced gene 5 protein(gene name synonym)|uniprotkb:Growth and transformation-dependent protein(gene name synonym)|uniprotkb:DC16(orf name)|uniprotkb:FWP001(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_055182.3|ensembl:ENSG00000114023(gene)|ensembl:ENST00000477892(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|interpro:IPR009432(Protein of unknown function DUF1075)|mint:Q96A26 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:CjOkqa9wFwEOorjQt5oI7/EJ6709606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q8WUY8 intact:EBI-25487672 intact:EBI-3919010|ensembl:ENSP00000205194|uniprotkb:Q8TDY7|uniprotkb:Q9NS72 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nat14_human(display_long)|uniprotkb:NAT14(gene name)|psi-mi:NAT14(display_short)|uniprotkb:KLP1(gene name synonym)|uniprotkb:K562 cell-derived leucine-zipper-like protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000090971(gene)|ensembl:ENST00000205194(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:Q8WUY8|refseq:NP_065111.1 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:zAcaUhoopgHpFaxfNM6H4jd4d089606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q8WTV0 intact:EBI-25487672 intact:EBI-78657|uniprotkb:Q52LZ5|uniprotkb:Q14016|uniprotkb:Q6KFX4|ensembl:ENSP00000414979|uniprotkb:F8W8N0 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:scrb1_human(display_long)|uniprotkb:SCARB1(gene name)|psi-mi:SCARB1(display_short)|uniprotkb:CD36L1(gene name synonym)|uniprotkb:CLA1(gene name synonym)|uniprotkb:SR-BI(gene name synonym)|uniprotkb:CD36 antigen-like 1(gene name synonym)|uniprotkb:CD36 and LIMPII analogous 1(gene name synonym)|uniprotkb:Collagen type I receptor, thrombospondin receptor-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_005496.4|ensembl:ENSG00000073060(gene)|ensembl:ENST00000415380(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005215"(transporter activity)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010899"(regulation of phosphatidylcholine catabolic process)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015920"(lipopolysaccharide transport)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0035461"(vitamin transmembrane transport)|go:"GO:0042060"(wound healing)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070506"(high-density lipoprotein particle receptor activity)|go:"GO:0070508"(cholesterol import)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|reactome:R-HSA-3000471|reactome:R-HSA-8964011|refseq:NP_001076428.1 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:En6dno+bRV4EB8FC539pcRRMIvs9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q8NBX0 intact:EBI-25487672 intact:EBI-4289902|uniprotkb:Q9Y363|uniprotkb:Q8TAR0|ensembl:ENSP00000355467 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:scpdl_human(display_long)|uniprotkb:SCCPDH(gene name)|psi-mi:SCCPDH(display_short)|uniprotkb:CGI-49(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000143653(gene)|ensembl:ENST00000366510(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030496"(midbody)|go:"GO:0031093"(platelet alpha granule lumen)|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR032095|interpro:IPR036291|reactome:R-HSA-114608|refseq:NP_057086.2 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:3dd8OvU7odCDI/f4Ouk7CJYoxnI9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q8IUR0 intact:EBI-25487672 intact:EBI-3246160|ensembl:ENSP00000316990|ensembl:ENSP00000399025|ensembl:ENSP00000470262|uniprotkb:A8K7I6 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tppc5_human(display_long)|uniprotkb:TRAPPC5(gene name)|psi-mi:TRAPPC5(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000181029(gene)|ensembl:ENST00000317378(transcript)|ensembl:ENST00000596148(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:1990070"(TRAPPI protein complex)|go:"GO:1990071"(TRAPPII protein complex)|go:"GO:1990072"(TRAPPIII protein complex)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016696(TRAPP I complex, Trs31)|interpro:IPR024096|reactome:R-HSA-204005|reactome:R-HSA-8876198|ensembl:ENST00000426877(transcript)|refseq:NP_001035926.1|refseq:NP_001035927.1|refseq:NP_777554.1 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:mojNHWAAx2Vj20UWUjm0UJsHxnQ9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q7LGA3 intact:EBI-25487672 intact:EBI-5461291|ensembl:ENSP00000359581|uniprotkb:D3DT22|uniprotkb:O75036|uniprotkb:Q32NB5|uniprotkb:Q8TAC5|uniprotkb:Q9H441|uniprotkb:Q9NUJ9 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:hs2st_human(display_long)|uniprotkb:HS2ST1(gene name)|psi-mi:HS2ST1(display_short)|uniprotkb:HS2ST(gene name synonym)|uniprotkb:KIAA0448(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000153936(gene)|ensembl:ENST00000370550(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004394"(heparan sulfate 2-O-sulfotransferase activity)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0015015"(heparan sulfate proteoglycan biosynthetic process, enzymatic modification)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007734(Heparan sulphate 2-O-sulphotransferase)|interpro:IPR027417|mint:Q7LGA3|reactome:R-HSA-2022928|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|refseq:NP_001127964.1|refseq:NP_036394.1 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:96+iUitOmSLSpaEzhZu+9fZXLEQ9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q6ZRP7 intact:EBI-25487672 intact:EBI-11127401|uniprotkb:Q7Z7B6|uniprotkb:Q8N3G2|uniprotkb:A6NLB0|uniprotkb:Q86VV7|uniprotkb:Q5TB37|uniprotkb:A2CEE0|ensembl:ENSP00000351536 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:qsox2_human(display_long)|uniprotkb:QSOX2(gene name)|psi-mi:QSOX2(display_short)|uniprotkb:Neuroblastoma-derived sulfhydryl oxidase(gene name synonym)|uniprotkb:QSCN6L1(gene name synonym)|uniprotkb:Quiescin Q6-like protein 1(gene name synonym)|uniprotkb:SOXN(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_859052.3|ensembl:ENSG00000165661(gene)|ensembl:ENST00000358701(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017905|interpro:IPR036249|interpro:IPR036774|interpro:IPR039798|interpro:IPR040986|interpro:IPR041269|interpro:IPR042568 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:P58P7yZCL+dIpUXwETr5Ppt/SQw9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q6P1Q0 intact:EBI-25487672 intact:EBI-1549822|uniprotkb:B3KXK7|uniprotkb:A6NER7|uniprotkb:Q6X2E4|uniprotkb:Q6X2E5|uniprotkb:Q7L2G9|uniprotkb:Q7L690|uniprotkb:Q8WXW6|uniprotkb:Q96PK7|uniprotkb:Q9Y3X3|uniprotkb:Q9BY59|intact:EBI-10972516|ensembl:ENSP00000262055 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ltmd1_human(display_long)|uniprotkb:LETMD1(gene name)|psi-mi:LETMD1(display_short)|uniprotkb:Cervical cancer 1 proto-oncogene protein p40(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 2 protein(gene name synonym)|uniprotkb:HCRR-2(gene name synonym)|uniprotkb:HCCR-1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_056231.3|refseq:XP_006719402.1|refseq:XP_006719403.1|refseq:NP_001230618.1|ensembl:ENSG00000050426(gene)|ensembl:ENST00000262055(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043022"(ribosome binding)|interpro:IPR011685(LETM1-like)|interpro:IPR033122|interpro:IPR044202|mint:Q6P1Q0 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:iyp46kHqB7mu8W0BYCn64BDkVVU9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q5VT66 intact:EBI-25487672 intact:EBI-11903927|uniprotkb:A8K447|uniprotkb:B2D078|uniprotkb:Q5VVS9|uniprotkb:Q5VVT0|uniprotkb:Q5VVT1|uniprotkb:Q8N9P5|uniprotkb:Q96FN8|uniprotkb:Q9H6C7|ensembl:ENSP00000355877 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:marc1_human(display_long)|uniprotkb:MTARC1(gene name)|psi-mi:MTARC1(display_short)|uniprotkb:MARC1(gene name synonym)|uniprotkb:MOSC1(gene name synonym)|uniprotkb:Molybdenum cofactor sulfurase C-terminal domain-containing protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_073583.3|refseq:XP_011508202.1|refseq:XP_011508206.1|ensembl:ENSG00000186205(gene)|ensembl:ENST00000366910(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016661"(oxidoreductase activity, acting on other nitrogenous compounds as donors)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0051410"(detoxification of nitrogen compound)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|go:"GO:0098809"(nitrite reductase activity)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|rcsb pdb:6FW2|reactome:R-HSA-211945 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:MVnfGK30icFS28a9p6qf739MKYs9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q2TAA5 intact:EBI-25487672 intact:EBI-1048799|uniprotkb:A5PLP3|uniprotkb:Q5TAN9|uniprotkb:Q6DKI6|uniprotkb:Q96FI7|uniprotkb:B4DKW9|ensembl:ENSP00000430236 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:alg11_human(display_long)|uniprotkb:ALG11(gene name)|psi-mi:ALG11(display_short)|uniprotkb:GT8(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 11 homolog(gene name synonym)|uniprotkb:Glycolipid 2-alpha-mannosyltransferase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001004127.2|ensembl:ENSG00000253710(gene)|ensembl:ENST00000521508(transcript)|go:"GO:0000026"(alpha-1,2-mannosyltransferase activity)|go:"GO:0004377"("GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006490"(oligosaccharide-lipid intermediate biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR031814|interpro:IPR038013|reactome:R-HSA-446193|reactome:R-HSA-4551295 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:OjwuNTUYh/E2R1APeB1qD9lqsOs9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:Q12907 intact:EBI-25487672 intact:EBI-3915406|uniprotkb:Q53HH1|ensembl:ENSP00000303366 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:lman2_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)|uniprotkb:C5orf8(gene name synonym)|uniprotkb:Glycoprotein GP36b(gene name synonym)|uniprotkb:Lectin mannose-binding 2(gene name synonym)|uniprotkb:Vesicular integral-membrane protein 36(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_006807.1|ensembl:ENSG00000169223(gene)|ensembl:ENST00000303127(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035664|mint:Q12907|reactome:R-HSA-204005|reactome:R-HSA-5694530 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:goqUZGW9/lvVMWDAZS9csH3TqWY9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:P61006 intact:EBI-25487672 intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_005361.2|dip:DIP-43703N|ensembl:ENSG00000167461(gene)|ensembl:ENST00000300935(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:P00387 intact:EBI-25487672 intact:EBI-1046040|uniprotkb:O75675|uniprotkb:Q8TDL8|uniprotkb:Q8WTS8|uniprotkb:Q9UEN4|uniprotkb:Q9UEN5|uniprotkb:Q9UL55|uniprotkb:Q9UL56|uniprotkb:B1AHF2|uniprotkb:B7Z7L3|ensembl:ENSP00000338461 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nb5r3_human(display_long)|uniprotkb:Diaphorase-1(gene name synonym)|uniprotkb:CYB5R3(gene name)|psi-mi:CYB5R3(display_short)|uniprotkb:DIA1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001165132.1|refseq:NP_000389.1|refseq:NP_001123291.1|refseq:NP_015565.1|refseq:NP_001165131.1|ensembl:ENSG00000100243(gene)|ensembl:ENST00000352397(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043531"(ADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|mint:P00387|rcsb pdb:1M91|rcsb pdb:1UMK|reactome:R-HSA-196836|reactome:R-HSA-211945|reactome:R-HSA-6798695|interpro:IPR039261|dip:DIP-50463N - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:Q8JTO6AXZ8LE4FXZAzOw2p4b6HY9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:O94766 intact:EBI-25487672 intact:EBI-3917958|uniprotkb:B7ZAB3|uniprotkb:Q9UEP0|uniprotkb:Q96I06|ensembl:ENSP00000265471 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:b3ga3_human(display_long)|uniprotkb:B3GAT3(gene name)|psi-mi:B3GAT3(display_short)|uniprotkb:Beta-1,3-glucuronyltransferase 3(gene name synonym)|uniprotkb:Glucuronosyltransferase I(gene name synonym)|uniprotkb:"UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001275652.1|refseq:NP_036332.2|ensembl:ENSG00000149541(gene)|ensembl:ENST00000265471(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0015018"(galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity)|go:"GO:0015020"(glucuronosyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050650"(chondroitin sulfate proteoglycan biosynthetic process)|go:"GO:0050651"(dermatan sulfate proteoglycan biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090316"(positive regulation of intracellular protein transport)|interpro:IPR005027(Glycosyl transferase, family 43)|interpro:IPR029044|mint:O94766|rcsb pdb:1FGG|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|rcsb pdb:3CU0|reactome:R-HSA-1971475|reactome:R-HSA-3560801|rcsb pdb:1KWS - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:Yay8m8ZubBSmSoywX2Zk/dYNdzA9606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037314 uniprotkb:A8MTT3 intact:EBI-25487672 intact:EBI-20869809|ensembl:ENSP00000380254|ensembl:ENSP00000380403|ensembl:ENSP00000383895|ensembl:ENSP00000384331|ensembl:ENSP00000384813|uniprotkb:A8MUR5 psi-mi:p0c6x7-pro_0000037314(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cebos_human(display_long)|uniprotkb:CEBPZ antisense RNA 1(gene name synonym)|uniprotkb:CEBPZ opposite strand(gene name synonym)|uniprotkb:CEBPZOS(gene name)|psi-mi:CEBPZOS(display_short)|uniprotkb:CEBPZ-AS1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377188|imex:IM-28441-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000218739(gene)|ensembl:ENST00000392061(transcript)|ensembl:ENST00000397064(transcript)|ensembl:ENST00000397226(transcript)|ensembl:ENST00000402297(transcript)|ensembl:ENST00000406711(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR037764|refseq:NP_001309302.1|refseq:NP_001309303.1|refseq:NP_001309304.1|refseq:NP_001309305.1|refseq:XP_016858595.1|refseq:XP_016858596.1|refseq:XP_016858597.1|refseq:XP_016858598.1 - chain-seq-start:3837|chain-seq-end:3919 - figure legend:Table 2, no 16|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:95nEGuIgfxXAK4CVWXC+sH1eT+c694009 rogid:5v9fW8kybAkjQE12Qk6CcTdC3+89606 rigid:SY2dNSIeP6aJTxkp3SNLRS6IhsA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9BSC4 intact:EBI-25487941 intact:EBI-7001376|uniprotkb:Q53RC9|uniprotkb:Q9H855|uniprotkb:Q96TA5|uniprotkb:Q9H7Y7|uniprotkb:A8K3R5|intact:MINT-3060916|uniprotkb:B4DLV0|ensembl:ENSP00000371101 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:nol10_human(display_long)|uniprotkb:NOL10(gene name)|psi-mi:NOL10(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_079170.2|refseq:NP_001248323.1|refseq:NP_001248321.1|ensembl:ENSG00000115761(gene)|ensembl:ENST00000381685(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012580(NUC153)|interpro:IPR036322|interpro:IPR040382|mint:Q9BSC4 - chain-seq-start:3920|chain-seq-end:4117 comment:mint figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:PiblslntTRSvRQnk82fSgtVJbXE9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9Y3B7 intact:EBI-25487941 intact:EBI-5453723|ensembl:ENSP00000308897|uniprotkb:A8K219|uniprotkb:Q32P46|uniprotkb:Q96Q73|uniprotkb:A6NLT0 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:rm11_human(display_long)|uniprotkb:MRPL11(gene name)|psi-mi:MRPL11(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL11m(gene name synonym)|uniprotkb:CGI-113(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000174547(gene)|ensembl:ENST00000310999(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020784|interpro:IPR036769|interpro:IPR036796|mint:Q9Y3B7|refseq:NP_057134.1|refseq:NP_733934.1|refseq:NP_733935.1|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:eTr4vzze0vg1fxw97n9C/lXYssU9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9NQT5 intact:EBI-25487941 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9NQT4 intact:EBI-25487941 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q8NEJ9 intact:EBI-25487941 intact:EBI-9995414|uniprotkb:A8K760|uniprotkb:Q9Y400|ensembl:ENSP00000386134 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ngdn_human(display_long)|uniprotkb:NGDN(gene name)|psi-mi:NGDN(display_short)|uniprotkb:C14orf120(gene name synonym)|uniprotkb:Centromere accumulated nuclear protein 1(gene name synonym)|uniprotkb:EIF4E-binding protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001036100.1|refseq:NP_056329.1|ensembl:ENSG00000129460(gene)|ensembl:ENST00000408901(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006417"(regulation of translation)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032040"(small-subunit processome)|interpro:IPR007146(Small-subunit processome, Utp3)|mint:Q8NEJ9 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:dzn7QntKCrb97VLlmUMizp+0CV49606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:P82675 intact:EBI-25487941 intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS5m(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_114108.1|ensembl:ENSG00000144029(gene)|ensembl:ENST00000272418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6RW5|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9ULT8 intact:EBI-25487941 intact:EBI-310559|uniprotkb:Q6P445|uniprotkb:Q86VJ1|uniprotkb:Q96F34|uniprotkb:Q9UFZ7|uniprotkb:D3DS86|ensembl:ENSP00000382269|ensembl:ENSP00000450697 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:hecd1_human(display_long)|uniprotkb:HECTD1(gene name)|psi-mi:HECTD1(display_short)|uniprotkb:KIAA1131(gene name synonym)|uniprotkb:HECT domain-containing protein 1(gene name synonym)|uniprotkb:E3 ligase for inhibin receptor(gene name synonym)|uniprotkb:EULIR(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000092148(gene)|ensembl:ENST00000399332(transcript)|ensembl:ENST00000553700(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035904"(aorta development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR000569(HECT)|interpro:IPR002110(Ankyrin)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010606(Mib-herc2)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020683|interpro:IPR035983|interpro:IPR036770|interpro:IPR037252|interpro:IPR041200|mint:Q9ULT8|rcsb pdb:2DK3|rcsb pdb:3DKM|reactome:R-HSA-983168|rcsb pdb:2LC3|refseq:XP_005267559.2|ensembl:ENSP00000382269|ensembl:ENSP00000450697|refseq:NP_056197.3|dip:DIP-31669N - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:/l60ZSm+P4Vlc8B79wS7+T1Zvzk9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9UL40 intact:EBI-25487941 intact:EBI-2462313|uniprotkb:B7Z367|uniprotkb:Q68CV9|uniprotkb:Q6ZMW1|ensembl:ENSP00000350869 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:zn346_human(display_long)|uniprotkb:ZNF346(gene name)|psi-mi:ZNF346(display_short)|uniprotkb:JAZ(gene name synonym)|uniprotkb:Just another zinc finger protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001295142.1|refseq:NP_001295143.1|refseq:NP_001295148.1|refseq:NP_001295152.1|refseq:NP_036411.1|refseq:XP_016864784.1|refseq:XP_016864785.1|ensembl:ENSG00000113761(gene)|ensembl:ENST00000358149(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0035198"(miRNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2MKD|rcsb pdb:2MKN - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:bK/y4NYSSsa1tcNjtbmsEmkSp7Q9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9UGI8 intact:EBI-25487941 intact:EBI-2561654|uniprotkb:Q9HAJ9|uniprotkb:Q9GZQ1|uniprotkb:A4D0U6|ensembl:ENSP00000350937 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:tes_human(display_long)|uniprotkb:TESS(gene name synonym)|uniprotkb:TES(gene name)|psi-mi:TES(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_056456.1|refseq:NP_690042.1|ensembl:ENSG00000135269(gene)|ensembl:ENST00000358204(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR027683|interpro:IPR033724|interpro:IPR034958|interpro:IPR034959|interpro:IPR034960|mint:Q9UGI8|rcsb pdb:2IYB|rcsb pdb:2XQN - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:19bO7/55OMgcMT5lx1404AluskE9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9NY61 intact:EBI-25487941 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q9H6F5 intact:EBI-25487941 intact:EBI-721289|uniprotkb:B4DY99|ensembl:ENSP00000227520 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ccd86_human(display_long)|uniprotkb:Cytokine-induced protein with coiled-coil domain(gene name synonym)|uniprotkb:CYCLON(gene name synonym)|uniprotkb:CCDC86(gene name)|psi-mi:CCDC86(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_077003.1|ensembl:ENSG00000110104(gene)|ensembl:ENST00000227520(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR005579(Cgr1)|interpro:IPR026570|mint:Q9H6F5 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:dRd5UWPzAehh8OFqkWrMMCnYYug9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q96FK6 intact:EBI-25487941 intact:EBI-720262|ensembl:ENSP00000267522|ensembl:ENSP00000378399|ensembl:ENSP00000480112 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:wdr89_human(display_long)|uniprotkb:WDR89(gene name)|psi-mi:WDR89(display_short)|uniprotkb:C14orf150(gene name synonym)|uniprotkb:MSTP050(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001008726.1|refseq:NP_542397.1|refseq:XP_011534687.1|ensembl:ENSG00000140006(gene)|ensembl:ENST00000267522(transcript)|ensembl:ENST00000394942(transcript)|ensembl:ENST00000620954(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR039328|refseq:NP_001245201.1 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:t+duI9WjwVSqm4/8JrqCEaZjG209606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q96B26 intact:EBI-25487941 intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:y/cReHiPMubzNruyETohBjbRick9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q8N983 intact:EBI-25487941 intact:EBI-1043145|ensembl:ENSP00000315364|uniprotkb:Q5JW06|uniprotkb:Q7Z719|uniprotkb:Q7Z7H6|uniprotkb:Q86XN1|uniprotkb:Q9BYC7|uniprotkb:B1AL09|uniprotkb:B1AL07|uniprotkb:B1AL10|intact:EBI-1047104|uniprotkb:D3DR71|uniprotkb:B1AL06|uniprotkb:C9J5Q3 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:rm43_human(display_long)|uniprotkb:Mitochondrial ribosomal protein bMRP36a(gene name synonym)|uniprotkb:MRPL43(gene name)|psi-mi:MRPL43(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL43(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|ensembl:ENSG00000055950(gene)|ensembl:ENST00000318325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR039927|mint:Q8N983|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:7A5I|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|refseq:NP_789764.1|refseq:XP_006718098.1|refseq:NP_115488.2|refseq:NP_789762.1|refseq:NP_789763.1|refseq:NP_001295325.1|ensembl:ENST00000299179|ensembl:ENSP00000299179|ensembl:ENSP00000315364|ensembl:ENST00000318364|ensembl:ENSP00000315948|ensembl:ENST00000342071|ensembl:ENSP00000339844|ensembl:ENST00000370234|ensembl:ENSP00000359254|ensembl:ENST00000370236|ensembl:ENSP00000359256|ensembl:ENST00000370242|ensembl:ENSP00000359262|refseq:XP_005270288.1 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:p3wPkljBAhx4IwvXsvfXDaEvpag9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q8IY37 intact:EBI-25487941 intact:EBI-308285|uniprotkb:Q9BUI7|uniprotkb:Q9P211|ensembl:ENSP00000311135 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:dhx37_human(display_long)|uniprotkb:DHX37(gene name)|psi-mi:DHX37(display_short)|uniprotkb:DDX37(gene name synonym)|uniprotkb:KIAA1517(gene name synonym)|uniprotkb:DEAH box protein 37(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_116045.2|ensembl:ENSG00000150990(gene)|ensembl:ENST00000308736(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007420"(brain development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042255"(ribosome assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q8IY37|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:y+2TFmurlGgCJ2pjTjfAttqC3xE9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q7L2J0 intact:EBI-25487941 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q4G0J3 intact:EBI-25487941 intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-2560173|ensembl:ENSP00000314311|ensembl:ENSP00000344950|ensembl:ENSP00000499190 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_056269.1|refseq:NP_057732.2|refseq:NP_001253968.1|dip:DIP-47624N|ensembl:ENSG00000174720(gene)|ensembl:ENST00000324052(transcript)|ensembl:ENST00000344442(transcript)|ensembl:ENST00000651579(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q15397 intact:EBI-25487941 intact:EBI-725523|uniprotkb:Q547G7|uniprotkb:Q5SZY9|uniprotkb:Q6IB47|uniprotkb:Q96B27|uniprotkb:Q96L78|uniprotkb:Q96L79|uniprotkb:Q96L80|uniprotkb:A8K804|ensembl:ENSP00000380982 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:pum3_human(display_long)|uniprotkb:PUM3(gene name)|psi-mi:PUM3(display_short)|uniprotkb:cPERP-C(gene name synonym)|uniprotkb:HBV X-transactivated gene 5 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 5(gene name synonym)|uniprotkb:KIAA0020(gene name synonym)|uniprotkb:Minor histocompatibility antigen HA-8(gene name synonym)|uniprotkb:PUF-A(gene name synonym)|uniprotkb:XTP5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_055693.4|ensembl:ENSG00000080608(gene)|ensembl:ENST00000397885(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006417"(regulation of translation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|interpro:IPR001313(Pumilio RNA-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012959(CPL)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033133|interpro:IPR040059|mint:Q15397|rcsb pdb:4WZR|rcsb pdb:4WZW - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:CjfVWg+3P3ai0EiHgeH8usbvgxg9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q14692 intact:EBI-25487941 intact:EBI-2513630|ensembl:ENSP00000363642|uniprotkb:Q86XJ9|uniprotkb:Q5QPT5 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:bms1_human(display_long)|uniprotkb:BMS1(gene name)|psi-mi:BMS1(display_short)|uniprotkb:BMS1L(gene name synonym)|uniprotkb:KIAA0187(gene name synonym)|uniprotkb:Ribosome assembly protein BMS1 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000165733(gene)|ensembl:ENST00000374518(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0030686"(90S preribosome)|go:"GO:0034511"(U3 snoRNA binding)|interpro:IPR007034(Protein of unknown function DUF663)|interpro:IPR012948(AARP2CN)|interpro:IPR027417|interpro:IPR030387|interpro:IPR037875|interpro:IPR039761|mint:Q14692|reactome:R-HSA-6790901|reactome:R-HSA-6791226|go:"GO:0005730"(nucleolus)|refseq:XP_011538704.1|refseq:NP_055568.3|refseq:XP_005271903.1 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:9sd7sK6/Ue4DgLRT+j9Iw0+8om09606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:Q13206 intact:EBI-25487941 intact:EBI-2514399|ensembl:ENSP00000314348|uniprotkb:Q5BJD8|uniprotkb:B2RCQ3 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ddx10_human(display_long)|uniprotkb:DDX10(gene name)|psi-mi:DDX10(display_short)|uniprotkb:DEAD box protein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000178105(gene)|ensembl:ENST00000322536(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0097065"(anterior head development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313|interpro:IPR027417|mint:Q13206|rcsb pdb:2PL3|refseq:NP_004389.2 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:MMAbABrYQHlYDyPsagT7oY92Z3M9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:P09132 intact:EBI-25487941 intact:EBI-2680090|uniprotkb:B2R4E9|uniprotkb:Q96FG6|uniprotkb:Q05D77|uniprotkb:D6RCQ5|ensembl:ENSP00000424870 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:srp19_human(display_long)|uniprotkb:SRP19(gene name)|psi-mi:SRP19(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001191123.1|refseq:NP_003126.1|refseq:NP_001191122.1|refseq:NP_001191125.1|ensembl:ENSG00000153037(gene)|ensembl:ENST00000505459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR036521|mint:P09132|rcsb pdb:1JID|rcsb pdb:1MFQ|rcsb pdb:1RY1|rcsb pdb:2J37|rcsb pdb:3KTV|rcsb pdb:4P3E|rcsb pdb:5M73|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-41412N - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:yIFmf1q6m2wQt3eaiCc1dlIQXn89606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:O95260 intact:EBI-25487941 intact:EBI-1043378|uniprotkb:O95261|uniprotkb:Q8WW04|ensembl:ENSP00000224652|uniprotkb:Q5SQQ3 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:ate1_human(display_long)|uniprotkb:Arginine-tRNA--protein transferase 1(gene name synonym)|uniprotkb:ATE1(gene name)|psi-mi:ATE1(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000107669(gene)|ensembl:ENST00000224652(transcript)|interpro:IPR007471(Arginine-tRNA-protein transferase, N-terminal)|interpro:IPR007472(Arginine-tRNA-protein transferase, C-terminal)|go:"GO:0004057"(arginyltransferase activity)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017137(Arginine-tRNA--protein transferase 1, eukaryotic)|go:"GO:0005634"(nucleus)|interpro:IPR030700|mint:O95260|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016598"(protein arginylation)|refseq:NP_001001976.1|refseq:NP_008972.2|refseq:NP_001275663.1|refseq:NP_001275664.1|refseq:NP_001275665.1 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:vK21nNxx2fa9ct7O5WG0LqtD9u09606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:O76094 intact:EBI-25487941 intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037315 uniprotkb:O00566 intact:EBI-25487941 intact:EBI-5235884|uniprotkb:A0AVJ8|ensembl:ENSP00000244230 psi-mi:p0c6x7-pro_0000037315(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short) psi-mi:mpp10_human(display_long)|uniprotkb:MPHOSPH10(gene name)|psi-mi:MPHOSPH10(display_short)|uniprotkb:MPP10(gene name synonym)|uniprotkb:M phase phosphoprotein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377216|imex:IM-28441-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_005782.1|ensembl:ENSG00000124383(gene)|ensembl:ENST00000244230(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034457"(Mpp10 complex)|interpro:IPR012173(U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p)|mint:O00566|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - chain-seq-start:3920|chain-seq-end:4117 - figure legend:Table 2, no 17|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:3oIsD98B0aiO0Sqlv5jCglM4pgE694009 rogid:xkz11U1x5r2joVtVq6JG4asO1Qw9606 rigid:mX+she2ck6Mtofkcxy/SP3h7Mk4 false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:P35556 intact:EBI-25475825 intact:EBI-6164392|ensembl:ENSP00000424571|ensembl:ENSP00000262464|uniprotkb:B4DU01|uniprotkb:Q59ES6 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fbn2_human(display_long)|uniprotkb:FBN2(gene name)|psi-mi:FBN2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377247|imex:IM-28441-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35556|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|interpro:IPR018097|ensembl:ENSG00000138829(gene)|ensembl:ENST00000262464(transcript)|ensembl:ENST00000508053(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|refseq:NP_001990.2 - chain-seq-start:4118|chain-seq-end:4230 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:iqBnjHuy9kU3serIc5tPWGIDzUc9606 rigid:nSqtD01JWiNCZRURrC9le14RriI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:Q8TD19 intact:EBI-25475825 intact:EBI-1044009|uniprotkb:Q52LK6|uniprotkb:Q8NCN0|uniprotkb:Q8TCY4|uniprotkb:Q9UPI4|uniprotkb:Q9Y6S4|uniprotkb:Q9Y6S5|uniprotkb:Q9Y6S6|intact:EBI-28978800|ensembl:ENSP00000238616 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:nek9_human(display_long)|uniprotkb:NEK9(gene name)|psi-mi:NEK9(display_short)|uniprotkb:KIAA1995(gene name synonym)|uniprotkb:NEK8(gene name synonym)|uniprotkb:NERCC(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 9(gene name synonym)|uniprotkb:Nercc1 kinase(gene name synonym)|uniprotkb:NimA-related kinase 8(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377247|imex:IM-28441-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) refseq:NP_149107.4|ensembl:ENSG00000119638(gene)|ensembl:ENST00000238616(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011009(Protein kinase-like)|interpro:IPR042767|mint:Q8TD19|rcsb pdb:3ZKE|rcsb pdb:3ZKF|reactome:R-HSA-2980767|reactome:R-HSA-3301854|reactome:R-HSA-9648025|ensembl:ENSP00000238616|refseq:NP_001316166.1|refseq:NP_001316167.1 - chain-seq-start:4118|chain-seq-end:4230 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:nH92Hku490dDttw5Akug+NjXRNY9606 rigid:nSqtD01JWiNCZRURrC9le14RriI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:Q8N1G2 intact:EBI-25475825 intact:EBI-2691086|uniprotkb:Q96FJ9|uniprotkb:Q14670|uniprotkb:A8K949|ensembl:ENSP00000362550 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:cmtr1_human(display_long)|uniprotkb:CMTR1(gene name)|psi-mi:CMTR1(display_short)|uniprotkb:Cap methyltransferase 1(gene name synonym)|uniprotkb:Cap1 2'O-ribose methyltransferase 1(gene name synonym)|uniprotkb:FTSJD2(gene name synonym)|uniprotkb:FtsJ methyltransferase domain-containing protein 2(gene name synonym)|uniprotkb:Interferon-stimulated gene 95 kDa protein(gene name synonym)|uniprotkb:KIAA0082(gene name synonym)|uniprotkb:MTR1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377247|imex:IM-28441-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) refseq:NP_055865.1|ensembl:ENSG00000137200(gene)|ensembl:ENST00000373451(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0080009"(mRNA methylation)|go:"GO:0097309"(cap1 mRNA methylation)|interpro:IPR000467(D111/G-patch)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR025816|interpro:IPR029063|interpro:IPR030376|mint:Q8N1G2|rcsb pdb:4N48|rcsb pdb:4N49|rcsb pdb:4N4A - chain-seq-start:4118|chain-seq-end:4230 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:mMoDk5J/tBCaxISq1Oju9BY0RVA9606 rigid:nSqtD01JWiNCZRURrC9le14RriI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:Q8N0X7 intact:EBI-25475825 intact:EBI-2643803|uniprotkb:Q9H1T3|uniprotkb:Q9H1T2|uniprotkb:O60349|uniprotkb:Q86Y67|ensembl:ENSP00000347314|ensembl:ENSP00000406061|ensembl:ENSP00000414147|ensembl:ENSP00000473599|ensembl:ENSP00000497209 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:spart_human(display_long)|uniprotkb:SPART(gene name)|psi-mi:SPART(display_short)|uniprotkb:KIAA0610(gene name synonym)|uniprotkb:SPG20(gene name synonym)|uniprotkb:Spastic paraplegia 20 protein(gene name synonym)|uniprotkb:TAHCCP1(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377247|imex:IM-28441-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) refseq:NP_001135766.1|refseq:NP_001135767.1|refseq:NP_001135768.1|refseq:NP_055902.1|refseq:XP_011533314.1|refseq:XP_005266370.1|refseq:XP_005266371.1|refseq:XP_005266372.1|ensembl:ENSG00000133104(gene)|ensembl:ENST00000355182(transcript)|ensembl:ENST00000438666(transcript)|ensembl:ENST00000451493(transcript)|ensembl:ENST00000494062(transcript)|ensembl:ENST00000650221(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009838"(abscission)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0045202"(synapse)|go:"GO:0048698"(negative regulation of collateral sprouting in absence of injury)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051301"(cell division)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060612"(adipose tissue development)|interpro:IPR007330(MIT)|interpro:IPR009686(Senescence-associated)|interpro:IPR036181|rcsb pdb:2DL1|rcsb pdb:4U7I|go:"GO:0030514"(negative regulation of BMP signaling pathway)|refseq:XP_005266374.1 - chain-seq-start:4118|chain-seq-end:4230 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:Km2bYRg7JLYy7voEgYVdAHZhzE09606 rigid:nSqtD01JWiNCZRURrC9le14RriI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:Q86YT6 intact:EBI-25475825 intact:EBI-2129148|uniprotkb:Q2TB37|uniprotkb:Q68D01|uniprotkb:Q6YI51|uniprotkb:Q8NBY0|uniprotkb:Q8TCB5|uniprotkb:Q8TCL7|uniprotkb:Q9P2M3|uniprotkb:B0YJ38|ensembl:ENSP00000261537 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mib1_human(display_long)|uniprotkb:MIB1(gene name)|psi-mi:MIB1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:KIAA1323(gene name synonym)|uniprotkb:ZZANK2(gene name synonym)|uniprotkb:Mind bomb homolog 1(gene name synonym)|uniprotkb:DAPK-interacting protein 1(gene name synonym)|uniprotkb:Zinc finger ZZ type with ankyrin repeat domain protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377247|imex:IM-28441-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) refseq:NP_065825.1|ensembl:ENSG00000101752(gene)|ensembl:ENST00000261537(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001947"(heart looping)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR010606(Mib-herc2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|interpro:IPR043145|mint:Q86YT6|rcsb pdb:4TSE|rcsb pdb:4XI6|rcsb pdb:4XI7|rcsb pdb:4XIB|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507 - chain-seq-start:4118|chain-seq-end:4230 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:+DhNmSTvuXexGhi2FyEuBv4pBiw9606 rigid:nSqtD01JWiNCZRURrC9le14RriI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:Q14232 intact:EBI-25475825 intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|uniprotkb:B4DGX0|ensembl:ENSP00000416250 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ei2ba_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377247|imex:IM-28441-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) refseq:NP_001405.1|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|ensembl:ENSG00000111361(gene)|ensembl:ENST00000424014(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related) - chain-seq-start:4118|chain-seq-end:4230 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606 rigid:nSqtD01JWiNCZRURrC9le14RriI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:P61962 intact:EBI-25475825 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377247|imex:IM-28441-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N - chain-seq-start:4118|chain-seq-end:4230 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rigid:nSqtD01JWiNCZRURrC9le14RriI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C6X7-PRO_0000037316 uniprotkb:O00142 intact:EBI-25475825 intact:EBI-25807889|ensembl:ENSP00000440898|uniprotkb:B4DGJ7|uniprotkb:B4DZK7|uniprotkb:B7ZAB1|uniprotkb:E5KNQ5|uniprotkb:E9PH08|uniprotkb:O15238 psi-mi:p0c6x7-pro_0000037316(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:kitm_human(display_long)|uniprotkb:TK2(gene name)|psi-mi:TK2(display_short)|uniprotkb:Mt-TK(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377247|imex:IM-28441-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent) ensembl:ENSG00000166548(gene)|ensembl:ENST00000544898(transcript)|go:"GO:0004137"(deoxycytidine kinase activity)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0019136"(deoxynucleoside kinase activity)|go:"GO:0019206"(nucleoside kinase activity)|go:"GO:0043097"(pyrimidine nucleoside salvage)|go:"GO:0046092"(deoxycytidine metabolic process)|go:"GO:0046104"(thymidine metabolic process)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR002624(Deoxynucleoside kinase)|interpro:IPR027417|interpro:IPR031314|reactome:R-HSA-73614|refseq:NP_001166114.1|refseq:NP_001166115.1|refseq:NP_001258864.1|refseq:NP_001258979.1|refseq:NP_004605.4 - chain-seq-start:4118|chain-seq-end:4230 - figure legend:Table 2, no 18|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:djbtL5LNKDagWRnaJOlJM8BS5lU694009 rogid:R14jrjOmUaQzRPk8MtgLozv13Mk9606 rigid:nSqtD01JWiNCZRURrC9le14RriI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59632 uniprotkb:Q96S66 intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5 intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|ensembl:ENSP00000349456|ensembl:ENSP00000358986|ensembl:ENSP00000502251|ensembl:ENSP00000502457|ensembl:ENSP00000502648|ensembl:ENSP00000502836 psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name) psi-mi:clcc1_human(display_long)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377262|imex:IM-28441-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2 refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940(gene)|ensembl:ENST00000356970(transcript)|ensembl:ENST00000369969(transcript)|ensembl:ENST00000674849(transcript)|ensembl:ENST00000675508(transcript)|ensembl:ENST00000675654(transcript)|ensembl:ENST00000675956(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR009231(Mid-1-related chloride channel) - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009 rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606 rigid:cvng7NpZUqe94nSwDPAd2UNRByA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59632 uniprotkb:Q92734 intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5 intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1 psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name) psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377262|imex:IM-28441-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2 refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1 - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009 rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606 rigid:cvng7NpZUqe94nSwDPAd2UNRByA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59632 uniprotkb:O95573 intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5 intact:EBI-1190822|uniprotkb:Q60I92|uniprotkb:Q8IUM9|ensembl:ENSP00000350012|ensembl:ENSP00000375918|ensembl:ENSP00000504861|ensembl:ENSP00000504907|ensembl:ENSP00000505400|ensembl:ENSP00000505654|ensembl:ENSP00000505793|ensembl:ENSP00000505856|ensembl:ENSP00000505940|ensembl:ENSP00000506361|ensembl:ENSP00000506468|intact:EBI-21359981 psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name) psi-mi:acsl3_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:ACSL3(gene name)|psi-mi:ACSL3(display_short)|uniprotkb:ACS3(gene name synonym)|uniprotkb:FACL3(gene name synonym)|uniprotkb:LACS3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase 3(gene name synonym)|uniprotkb:Medium-chain acyl-CoA ligase Acsl3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377262|imex:IM-28441-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2 refseq:NP_004448.2|refseq:NP_976251.1|refseq:XP_016859073.1|ensembl:ENSG00000123983(gene)|ensembl:ENST00000357430(transcript)|ensembl:ENST00000392066(transcript)|ensembl:ENST00000679514(transcript)|ensembl:ENST00000679558(transcript)|ensembl:ENST00000680147(transcript)|ensembl:ENST00000680251(transcript)|ensembl:ENST00000680395(transcript)|ensembl:ENST00000680684(transcript)|ensembl:ENST00000680921(transcript)|ensembl:ENST00000681383(transcript)|ensembl:ENST00000681697(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|mint:O95573|reactome:R-HSA-434313|reactome:R-HSA-75876 - - - figure legend:Table 2, no 19|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009 rogid:L5tCBPOlL45uh0aUFi4algZQ5nY9606 rigid:cvng7NpZUqe94nSwDPAd2UNRByA false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59634 uniprotkb:P35658 intact:EBI-25489038|uniprotkb:Q7T6R9|uniprotkb:Q7TA25|uniprotkb:Q7TFA7|uniprotkb:Q80BV3 intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400 psi-mi:ns6_sars(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377272|imex:IM-28441-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:NP_828856.1 ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FbI4KIsNxOBCtk9JMPiabQsxtXM694009 rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606 rigid:qhdOELZcY+cUsPue2Dd2qSJaFlg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59634 uniprotkb:Q9HBL7 intact:EBI-25489038|uniprotkb:Q7T6R9|uniprotkb:Q7TA25|uniprotkb:Q7TFA7|uniprotkb:Q80BV3 intact:EBI-714824|uniprotkb:Q9NZ44|uniprotkb:B2R6W0|ensembl:ENSP00000223864 psi-mi:ns6_sars(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:plrkt_human(display_long)|uniprotkb:PLGRKT(gene name)|psi-mi:PLGRKT(display_short)|uniprotkb:C9orf46(gene name synonym)|uniprotkb:AD025(orf name)|uniprotkb:MDS030(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377272|imex:IM-28441-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:NP_828856.1 refseq:XP_011516262.1|ensembl:ENSG00000107020(gene)|ensembl:ENST00000223864(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0010756"(positive regulation of plasminogen activation)|interpro:IPR019319|refseq:NP_060935.2|refseq:XP_005251567.1 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FbI4KIsNxOBCtk9JMPiabQsxtXM694009 rogid:qkj3WQL8jWUfNn4aQWO8RVidNUk9606 rigid:qhdOELZcY+cUsPue2Dd2qSJaFlg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59634 uniprotkb:Q9BWH2 intact:EBI-25489038|uniprotkb:Q7T6R9|uniprotkb:Q7TA25|uniprotkb:Q7TFA7|uniprotkb:Q80BV3 intact:EBI-714482|ensembl:ENSP00000358510|uniprotkb:Q9H2I6|uniprotkb:Q8NHX8|uniprotkb:B2R7W5|uniprotkb:D3DWY5 psi-mi:ns6_sars(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:fund2_human(display_long)|uniprotkb:HCC3(orf name)|uniprotkb:PD03104(orf name)|uniprotkb:FUNDC2(gene name)|psi-mi:FUNDC2(display_short)|uniprotkb:HCBP6(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 6(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 3 protein(gene name synonym)|uniprotkb:DC44(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377272|imex:IM-28441-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:NP_828856.1 ensembl:ENSG00000165775(gene)|ensembl:ENST00000369498(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR007014(FUN14)|refseq:NP_076423.2 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FbI4KIsNxOBCtk9JMPiabQsxtXM694009 rogid:oAN8aj9JpmBS5+YUfdh8Keehk3E9606 rigid:qhdOELZcY+cUsPue2Dd2qSJaFlg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59634 uniprotkb:Q96AQ6 intact:EBI-25489038|uniprotkb:Q7T6R9|uniprotkb:Q7TA25|uniprotkb:Q7TFA7|uniprotkb:Q80BV3 intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85 psi-mi:ns6_sars(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377272|imex:IM-28441-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:NP_828856.1 refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FbI4KIsNxOBCtk9JMPiabQsxtXM694009 rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606 rigid:qhdOELZcY+cUsPue2Dd2qSJaFlg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59634 uniprotkb:P78406 intact:EBI-25489038|uniprotkb:Q7T6R9|uniprotkb:Q7TA25|uniprotkb:Q7TFA7|uniprotkb:Q80BV3 intact:EBI-724495|uniprotkb:O15306|uniprotkb:Q3SYL7|uniprotkb:Q5TCH8|uniprotkb:Q6V708|uniprotkb:Q9H100|uniprotkb:Q9NQM6|ensembl:ENSP00000360286|ensembl:ENSP00000379181|ensembl:ENSP00000379182|uniprotkb:A8K882 psi-mi:ns6_sars(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:rae1l_human(display_long)|uniprotkb:mRNA-associated protein mrnp 41(gene name synonym)|uniprotkb:Rae1 protein homolog(gene name synonym)|uniprotkb:RAE1(gene name)|psi-mi:RAE1(display_short)|uniprotkb:MRNP41(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377272|imex:IM-28441-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:NP_828856.1 refseq:NP_001015885.1|refseq:NP_003601.1|ensembl:ENSG00000101146(gene)|ensembl:ENST00000371242(transcript)|ensembl:ENST00000395840(transcript)|ensembl:ENST00000395841(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037631|mint:P78406|rcsb pdb:3MMY|rcsb pdb:4OWR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|interpro:IPR019775|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|refseq:XP_011527390.1|refseq:XP_011527391.1|refseq:XP_005260639.2|dip:DIP-41063N - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FbI4KIsNxOBCtk9JMPiabQsxtXM694009 rogid:JK4Y5p3WUcHFXBXyhhqCnDnG49c9606 rigid:qhdOELZcY+cUsPue2Dd2qSJaFlg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59634 uniprotkb:P52948 intact:EBI-25489038|uniprotkb:Q7T6R9|uniprotkb:Q7TA25|uniprotkb:Q7TFA7|uniprotkb:Q80BV3 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:ns6_sars(display_long)|uniprotkb:Accessory protein 6(gene name synonym)|uniprotkb:Protein X3(gene name synonym)|uniprotkb:6(orf name)|uniprotkb:Non-structural protein 6(gene name synonym) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377272|imex:IM-28441-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016020"(membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044178"(host cell Golgi membrane)|interpro:IPR022736|refseq:NP_828856.1 refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - - figure legend:Table 2, no 20|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:FbI4KIsNxOBCtk9JMPiabQsxtXM694009 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 rigid:qhdOELZcY+cUsPue2Dd2qSJaFlg false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:Q92616 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:Q9Y6E2 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-1051021|uniprotkb:Q3B779|uniprotkb:Q9H3F7|uniprotkb:A4D123|uniprotkb:Q96JW5|ensembl:ENSP00000258761|ensembl:ENSP00000397249 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:bzw2_human(display_long)|uniprotkb:BZW2(gene name)|psi-mi:BZW2(display_short)|uniprotkb:HSPC028(orf name)|uniprotkb:MSTP017(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 refseq:NP_001153239.1|refseq:NP_054757.1|ensembl:ENSG00000136261(gene)|ensembl:ENST00000258761(transcript)|ensembl:ENST00000433922(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|refseq:XP_006715769.1|refseq:XP_006715770.1|refseq:XP_006715771.1 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:+z22Ykb6e3IM9zk51m6tjuhiEcU9606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:Q9Y678 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:Q9Y263 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-1994037|uniprotkb:Q53EU5|uniprotkb:Q5VY33|uniprotkb:Q9NUL8|uniprotkb:Q9NVE9|uniprotkb:Q9UF53|uniprotkb:Q9Y5L1|ensembl:ENSP00000380460 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:plap_human(display_long)|uniprotkb:PLAA(gene name)|psi-mi:PLAA(display_short)|uniprotkb:PLAP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 refseq:NP_001026859.1|ensembl:ENSG00000137055(gene)|ensembl:ENST00000397292(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010992"(ubiquitin recycling)|go:"GO:0016005"(phospholipase A2 activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1900045"(negative regulation of protein K63-linked ubiquitination)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013535(PUL)|interpro:IPR015155("PFU (PLAA family ubiquitin binding)")|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036322|interpro:IPR038122|mint:Q9Y263|rcsb pdb:2K89|rcsb pdb:2K8A|rcsb pdb:2K8B|rcsb pdb:2K8C|rcsb pdb:3EBB - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:SoClA00UzZpX9vV1cJWvefY6eY89606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:Q7Z4Q2 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|uniprotkb:A8K1N4|ensembl:ENSP00000299192 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 refseq:NP_891552.1|ensembl:ENSG00000155393(gene)|ensembl:ENST00000299192(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR016024(Armadillo-type fold)|mint:Q7Z4Q2 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:Q7L1Q6 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-1046727|ensembl:ENSP00000386474|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:bzw1_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 refseq:NP_001193996.1|refseq:NP_055485.2|ensembl:ENSG00000082153(gene)|ensembl:ENST00000409600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|mint:Q7L1Q6|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:Q5VYK3 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-521451|uniprotkb:O15074|uniprotkb:Q8WU82|ensembl:ENSP00000339889 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:ecm29_human(display_long)|uniprotkb:ECPAS(gene name)|psi-mi:ECPAS(display_short)|uniprotkb:ECM29(gene name synonym)|uniprotkb:Ecm29 proteasome adapter and scaffold(gene name synonym)|uniprotkb:KIAA0368(gene name synonym)|uniprotkb:Proteasome-associated protein ECM29 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 refseq:XP_005251907.1|ensembl:ENSG00000136813(gene)|ensembl:ENST00000338205(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005813"(centrosome)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043248"(proteasome assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024372|mint:Q5VYK3 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:lBqnwI2OO2aNvK1kjEpYOGK4oUI9606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:P46459 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:P42345 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-359260|uniprotkb:Q5TER1|uniprotkb:Q4LE76|uniprotkb:Q6LE87|uniprotkb:Q96QG3|uniprotkb:Q9Y4I3|ensembl:ENSP00000354558|intact:EBI-28989074 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:mtor_human(display_long)|uniprotkb:MTOR(gene name)|psi-mi:MTOR(display_short)|uniprotkb:FRAP(gene name synonym)|uniprotkb:FRAP2(gene name synonym)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:FRAP1(gene name synonym)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)|uniprotkb:RAFT1(gene name synonym)|uniprotkb:RAPT1(gene name synonym)|uniprotkb:Rapamycin and FKBP12 target 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 ensembl:ENSG00000198793(gene)|refseq:NP_004949.1|ensembl:ENST00000361445(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005764"(lysosome)|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6ZWM|rcsb pdb:6ZWO|reactome:R-HSA-1257604|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-6804757|reactome:R-HSA-8943724|reactome:R-HSA-9639288|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043276"(anoikis)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0008542"(visual learning)|go:"GO:1904058"(positive regulation of sensory perception of pain)|go:"GO:1904059"(regulation of locomotor rhythm)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904690"(positive regulation of cytoplasmic translational initiation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940|mint:P42345|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|rcsb pdb:1FAP|rcsb pdb:1NSG|rcsb pdb:2FAP|rcsb pdb:2GAQ|rcsb pdb:2NPU|rcsb pdb:2RSE|rcsb pdb:3FAP|rcsb pdb:3JBZ|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRJ|rcsb pdb:4FAP|rcsb pdb:4JSN|rcsb pdb:4JSP|rcsb pdb:4JSV|rcsb pdb:4JSX|rcsb pdb:4JT5|rcsb pdb:4JT6|rcsb pdb:5FLC|rcsb pdb:5GPG|rcsb pdb:5H64|rcsb pdb:5WBH|rcsb pdb:5WBU|rcsb pdb:5WBY|rcsb pdb:5ZCS|rcsb pdb:6BCU|rcsb pdb:1AUE|rcsb pdb:6BCX|rcsb pdb:6M4U|rcsb pdb:6M4W|go:"GO:0005789"(endoplasmic reticulum membrane)|ensembl:ENSP00000354558|refseq:XP_005263495.1|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005829"(cytosol)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007616"(long-term memory)|go:"GO:0008361"(regulation of cell size)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|dip:DIP-790N - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:z6uJxqv906jKZ7IqoavN5JTWJs09606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:O75691 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-356062|uniprotkb:Q9H3H4|ensembl:ENSP00000261637 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:utp20_human(display_long)|uniprotkb:UTP20(gene name)|psi-mi:UTP20(display_short)|uniprotkb:DRIM(gene name synonym)|uniprotkb:Down-regulated in metastasis protein(gene name synonym)|uniprotkb:Protein Key-1A6(gene name synonym)|uniprotkb:Novel nucleolar protein 73(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 refseq:NP_055318.2|ensembl:ENSG00000120800(gene)|ensembl:ENST00000261637(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000472"("endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0032040"(small-subunit processome)|interpro:IPR011430(Down-regulated in metastasis)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:OxTEfw2MtOijthWHjRtqIqUUjjg9606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59635 uniprotkb:O14787 intact:EBI-25492879|uniprotkb:Q7TA11|uniprotkb:Q7TA17 intact:EBI-431907|uniprotkb:O14655|intact:EBI-1053477|uniprotkb:Q6IN77|ensembl:ENSP00000407182|ensembl:ENSP00000468434 psi-mi:ns7a_sars(display_long)|uniprotkb:Accessory protein 7a(gene name synonym)|uniprotkb:Protein U122(gene name synonym)|uniprotkb:Protein X4(gene name synonym)|uniprotkb:7a(orf name) psi-mi:tnpo2_human(display_long)|uniprotkb:Karyopherin beta-2b(gene name synonym)|uniprotkb:TNPO2(gene name)|psi-mi:TNPO2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377285|imex:IM-28441-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR044871|go:"GO:0016021"(integral component of membrane)|go:"GO:0019051"(induction by virus of host apoptotic process)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|rcsb pdb:1XAK|rcsb pdb:1YO4|interpro:IPR014888(SARS coronavirus X4 like)|interpro:IPR036495|reactome:R-HSA-9678110|reactome:R-HSA-9679509|refseq:NP_828857.1 refseq:NP_001129668.1|refseq:NP_001129667.1|refseq:NP_038461.2|ensembl:ENSG00000105576(gene)|ensembl:ENST00000425528(transcript)|ensembl:ENST00000592287(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122 - - - figure legend:Table 2, no 21|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Es9fKGNXTAgB+97mHmPWTjXL8nU694009 rogid:B+ZqD5TWiP/J6/ZwiM+39lO9E749606 rigid:cD170BxUFAgyFKx2JlqupbSdsRo false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:P13667 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q9UMX5 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-11333667|uniprotkb:Q5TM90|uniprotkb:Q53FZ6|uniprotkb:A1KYQ8|ensembl:ENSP00000355955 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:nenf_human(display_long)|uniprotkb:NENF(gene name)|psi-mi:NENF(display_short)|uniprotkb:CIR2(gene name synonym)|uniprotkb:Cell immortalization-related protein 2(gene name synonym)|uniprotkb:Neuron-derived neurotrophic factor(gene name synonym)|uniprotkb:Protein GIG47(gene name synonym)|uniprotkb:SPUF(gene name synonym)|uniprotkb:Secreted protein of unknown function(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_037481.1|ensembl:ENSG00000117691(gene)|ensembl:ENST00000366988(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008083"(growth factor activity)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0032099"(negative regulation of appetite)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|go:"GO:0005739"(mitochondrion) - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:O80Y59kmx4FOQVWNTV2fJvQz0cg9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q9NYU2 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q9NVA1 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-11911675|uniprotkb:B1AKV5|uniprotkb:Q0VF37|uniprotkb:Q5T348|uniprotkb:Q5T351|uniprotkb:Q5T353|uniprotkb:Q86YU3|uniprotkb:Q86YU4|uniprotkb:Q96H66|uniprotkb:Q9H438|uniprotkb:Q9H452|uniprotkb:Q9H9K8|uniprotkb:Q9H9R5|ensembl:ENSP00000363506 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:uqcc1_human(display_long)|uniprotkb:UQCC1(gene name)|psi-mi:UQCC1(display_short)|uniprotkb:Basic FGF-repressed Zic-binding protein(gene name synonym)|uniprotkb:BZFB(gene name synonym)|uniprotkb:C20orf44(gene name synonym)|uniprotkb:UQCC(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_001171906.1|refseq:NP_060714.3|refseq:NP_955781.2|refseq:XP_011527184.1|refseq:XP_011527185.1|refseq:XP_011527186.1|ensembl:ENST00000374385(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|interpro:IPR007129(Ubiquinol-cytochrome C chaperone)|interpro:IPR021150|ensembl:ENSG00000101019(gene) - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:QFm9RgX6m+fMfaeRZMOtWyi7mwY9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q9NPA0 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q9H488 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-2564472|uniprotkb:A8K4R8|uniprotkb:Q14685|uniprotkb:Q5W185|uniprotkb:Q9BW76|uniprotkb:E1P5M4|ensembl:ENSP00000364902 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:ofut1_human(display_long)|uniprotkb:POFUT1(gene name)|psi-mi:POFUT1(display_short)|uniprotkb:FUT12(gene name synonym)|uniprotkb:KIAA0180(gene name synonym)|uniprotkb:Peptide-O-fucosyltransferase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_056167.1|refseq:NP_758436.1|ensembl:ENSG00000101346(gene)|ensembl:ENST00000375749(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006004"(fucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008417"(fucosyltransferase activity)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016266"(O-glycan processing)|go:"GO:0036066"(protein O-linked fucosylation)|go:"GO:0046922"(peptide-O-fucosyltransferase activity)|interpro:IPR019378|interpro:IPR039922|rcsb pdb:5UX6|rcsb pdb:5UXH|reactome:R-HSA-1912399 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:XqxIDXSKUkpXsbJSx0sN8tkbV3E9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q9BS26 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 ensembl:ENSG00000023318(gene)|ensembl:ENST00000262455(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009986"(cell surface)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|go:"GO:0009100"(glycoprotein metabolic process)|refseq:NP_055866.1 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:TpwaFRifveb03iRPS2pEZve1kLA9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q9BRT2 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-1054584|uniprotkb:B2R4I0|ensembl:ENSP00000476140 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:uqcc2_human(display_long)|uniprotkb:UQCC2(gene name)|psi-mi:UQCC2(display_short)|uniprotkb:Breast cancer-associated protein SGA-81M(gene name synonym)|uniprotkb:C6orf125(gene name synonym)|uniprotkb:MNF1(gene name synonym)|uniprotkb:Mitochondrial nucleoid factor 1(gene name synonym)|uniprotkb:Mitochondrial protein M19(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_115716.1|ensembl:ENSG00000137288(gene)|ensembl:ENST00000607484(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR037698 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:5bqVcfnTXOCOuCVCrEtzEaChT3Y9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q96HE7 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-2564539|uniprotkb:A8K9X4|uniprotkb:A8MYW1|uniprotkb:Q7LD45|uniprotkb:Q9P1Q9|uniprotkb:Q9UKV6|ensembl:ENSP00000379042 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:ero1a_human(display_long)|uniprotkb:ERO1A(gene name)|psi-mi:ERO1A(display_short)|uniprotkb:ERO1L(gene name synonym)|uniprotkb:Endoplasmic oxidoreductin-1-like protein(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductase alpha(gene name synonym)|uniprotkb:Oxidoreductin-1-L-alpha(gene name synonym)|uniprotkb:UNQ434/PRO865(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_055399.1|ensembl:ENSG00000197930(gene)|ensembl:ENST00000395686(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0010260"(animal organ senescence)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030425"(dendrite)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071949"(FAD binding)|interpro:IPR007266(Endoplasmic reticulum oxidoreductin 1)|interpro:IPR037192|mint:Q96HE7|rcsb pdb:3AHQ|rcsb pdb:3AHR|reactome:R-HSA-264876|reactome:R-HSA-3299685 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:7IOP99IQt+7MBAQ0LKqPo5mFylo9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q96AY3 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-2372475|uniprotkb:Q7Z3R4|uniprotkb:Q9H3N3|uniprotkb:Q9H6N5|uniprotkb:Q9UF89|uniprotkb:Q9H6J3|ensembl:ENSP00000317232 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:fkb10_human(display_long)|uniprotkb:FKBP10(gene name)|psi-mi:FKBP10(display_short)|uniprotkb:FKBP65(gene name synonym)|uniprotkb:FK506-binding protein 10(gene name synonym)|uniprotkb:Immunophilin FKBP65(gene name synonym)|uniprotkb:65 kDa FK506-binding protein(gene name synonym)|uniprotkb:PSEC0056(orf name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_068758.3|ensembl:ENSG00000141756(gene)|ensembl:ENST00000321562(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0018208"(peptidyl-proline modification)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042060"(wound healing)|go:"GO:0085029"(extracellular matrix assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q96AY3 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:+oJpWT3zBh/fq0DqKPapFoVt3u09606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q8NBJ5 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-1057068|uniprotkb:Q8NC64|ensembl:ENSP00000252599 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:gt251_human(display_long)|uniprotkb:COLGALT1(gene name)|psi-mi:COLGALT1(display_short)|uniprotkb:"Collagen beta(1-O)galactosyltransferase 1"(gene name synonym)|uniprotkb:GLT25D1(gene name synonym)|uniprotkb:Glycosyltransferase 25 family member 1(gene name synonym)|uniprotkb:Hydroxylysine galactosyltransferase 1(gene name synonym)|uniprotkb:PSEC0241(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_078932.2|ensembl:ENSG00000130309(gene)|ensembl:ENST00000252599(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:1904028"(positive regulation of collagen fibril organization)|interpro:IPR002654(Glycosyl transferase, family 25)|interpro:IPR029044|mint:Q8NBJ5|reactome:R-HSA-1650814 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:nB7wFmsUKfA2+PrPaqw08fQpJRs9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q8N766 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q6NUQ4 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-372318|uniprotkb:A6NNF2|uniprotkb:Q53SW1|uniprotkb:Q69YH4|uniprotkb:Q8WZ37|uniprotkb:Q9NXH2|uniprotkb:Q8NC45|uniprotkb:B3KUI9|uniprotkb:B5MCD8|ensembl:ENSP00000238788|ensembl:ENSP00000319469|uniprotkb:D6W547 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:tm214_human(display_long)|uniprotkb:TMEM214(gene name)|psi-mi:TMEM214(display_short)|uniprotkb:PP446(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 ensembl:ENSG00000119777(gene)|ensembl:ENST00000238788(transcript)|ensembl:ENST00000321326(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019308|mint:Q6NUQ4|refseq:NP_001077059.1|refseq:NP_060197.4 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:Yx4jp39AqeiXqOJVzMMRqRgk8449606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q4G0I0 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-21888141|uniprotkb:Q96RZ0|ensembl:ENSP00000413100 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:csmt1_human(display_long)|uniprotkb:CCSMST1(gene name)|psi-mi:CCSMST1(display_short)|uniprotkb:C16orf91(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_001258980.1|ensembl:ENSG00000174109(gene)|ensembl:ENST00000442039(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR023248|interpro:IPR029160 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:zAfjcZJ6I/B0LRqj/p2gkNb4eAk9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q15006 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:Q02809 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-357174|ensembl:ENSP00000196061|uniprotkb:Q96AV9|uniprotkb:Q9H132|uniprotkb:B4DR87|intact:EBI-21357524 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:plod1_human(display_long)|uniprotkb:PLOD(gene name synonym)|uniprotkb:PLOD1(gene name)|psi-mi:PLOD1(display_short)|uniprotkb:LLH(gene name synonym)|uniprotkb:Lysyl hydroxylase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 ensembl:ENSG00000083444(gene)|ensembl:ENST00000196061(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0008544"(epidermis development)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:Q02809|reactome:R-HSA-1650814|refseq:NP_000293.2|refseq:NP_001303249.1 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:q0eJHb8L3qTbN1PnjQ8L0PcpOLw9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:P40855 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798 - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:P27797 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:P07237 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TFA0 uniprotkb:O60568 intact:EBI-25492905|uniprotkb:Q7TLC8 intact:EBI-741582|uniprotkb:Q540C3|ensembl:ENSP00000223127|uniprotkb:B2R6W6 psi-mi:ns8a_sars(display_long)|uniprotkb:Accessory protein 8a(gene name synonym)|uniprotkb:Protein non-structural 8a(gene name synonym)|uniprotkb:8a(orf name) psi-mi:plod3_human(display_long)|uniprotkb:PLOD3(gene name)|psi-mi:PLOD3(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377303|imex:IM-28441-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022722|refseq:NP_849176.1 ensembl:ENSG00000106397(gene)|ensembl:ENST00000223127(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005506"(iron ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008104"(protein localization)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0021915"(neural tube development)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033823"(procollagen glucosyltransferase activity)|go:"GO:0042311"(vasodilation)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O60568|rcsb pdb:6FXK|rcsb pdb:6FXM|rcsb pdb:6FXR|rcsb pdb:6FXT|rcsb pdb:6FXX|rcsb pdb:6FXY|rcsb pdb:6TE3|rcsb pdb:6TEC|refseq:NP_001075.1|rcsb pdb:6TES|rcsb pdb:6TEU|rcsb pdb:6TEX|rcsb pdb:6TEZ|reactome:R-HSA-1650814|rcsb pdb:6WFV - - - figure legend:Table 2, no 22|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:Qi1RZccwqrBJVwiaxXlOG6EDqIk694009 rogid:dvfk+ko7squrB6c4AayW+fR8EnE9606 rigid:x3TNfxvOHzpL7AXugCzK0bkbQvI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80H93 uniprotkb:Q5JRX3 intact:EBI-25492924|uniprotkb:Q7TFA6 intact:EBI-2432778|uniprotkb:B4E0J8|uniprotkb:E7ES23|uniprotkb:B3KMJ6|uniprotkb:O95204|uniprotkb:Q2M2G6|uniprotkb:Q4VBR1|uniprotkb:Q5JRW7|uniprotkb:Q7L5Z7|uniprotkb:Q9BSI6|uniprotkb:Q9BVJ5|uniprotkb:Q9UPP8|uniprotkb:C9JSL2|ensembl:ENSP00000224949 psi-mi:ns8b_sars(display_long)|uniprotkb:Accessory protein 8b(gene name synonym)|uniprotkb:Non-structural protein 8b(gene name synonym)|uniprotkb:8b(orf name) psi-mi:prep_human(display_long)|uniprotkb:PITRM1(gene name)|psi-mi:PITRM1(display_short)|uniprotkb:KIAA1104(gene name synonym)|uniprotkb:MP1(gene name synonym)|uniprotkb:Pitrilysin metalloproteinase 1(gene name synonym)|uniprotkb:PREP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377331|imex:IM-28441-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR022722|reactome:R-HSA-9679504|refseq:NP_849177.1 refseq:NP_001229236.1|refseq:NP_001229238.1|refseq:NP_055704.2|dip:DIP-52900N|ensembl:ENSG00000107959(gene)|ensembl:ENST00000224949(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006508"(proteolysis)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR013578(Peptidase M16C associated)|mint:Q5JRX3|rcsb pdb:4L3T|rcsb pdb:4NGE|rcsb pdb:4RPU|reactome:R-HSA-1268020 - - - figure legend:Table 2, no 23|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:kClXFAtdU2CB5IfDfvI8H+CyNvQ694009 rogid:1kEY/XJB5fwgNRoM9u9ZGT+VrS09606 rigid:HbAGoCguUTrezul40Wi5/cdOBJI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80H93 uniprotkb:Q10713 intact:EBI-25492924|uniprotkb:Q7TFA6 intact:EBI-2514696|ensembl:ENSP00000360782|uniprotkb:Q8N513|uniprotkb:Q16639|uniprotkb:Q5SXM9|uniprotkb:B4DKL3|uniprotkb:E7ET61 psi-mi:ns8b_sars(display_long)|uniprotkb:Accessory protein 8b(gene name synonym)|uniprotkb:Non-structural protein 8b(gene name synonym)|uniprotkb:8b(orf name) psi-mi:mppa_human(display_long)|uniprotkb:PMPCA(gene name)|psi-mi:PMPCA(display_short)|uniprotkb:INPP5E(gene name synonym)|uniprotkb:KIAA0123(gene name synonym)|uniprotkb:MPPA(gene name synonym)|uniprotkb:Alpha-MPP(gene name synonym)|uniprotkb:P-55(gene name synonym)|uniprotkb:Inactive zinc metalloprotease alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377331|imex:IM-28441-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR022722|reactome:R-HSA-9679504|refseq:NP_849177.1 refseq:NP_001269875.1|ensembl:ENSG00000165688(gene)|ensembl:ENST00000371717(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-HSA-1268020|reactome:R-HSA-8949664|interpro:IPR037715|refseq:NP_001269873.1|refseq:NP_055975.1 - - - figure legend:Table 2, no 23|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:kClXFAtdU2CB5IfDfvI8H+CyNvQ694009 rogid:Kqz7qIyX2eUOcnNrfIsSPjc4Isw9606 rigid:HbAGoCguUTrezul40Wi5/cdOBJI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80H93 uniprotkb:P46199 intact:EBI-25492924|uniprotkb:Q7TFA6 intact:EBI-359432|ensembl:ENSP00000263629|ensembl:ENSP00000378099|ensembl:ENSP00000384481|uniprotkb:D6W5D0 psi-mi:ns8b_sars(display_long)|uniprotkb:Accessory protein 8b(gene name synonym)|uniprotkb:Non-structural protein 8b(gene name synonym)|uniprotkb:8b(orf name) psi-mi:if2m_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377331|imex:IM-28441-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR022722|reactome:R-HSA-9679504|refseq:NP_849177.1 refseq:NP_001307933.1|refseq:NP_001307934.1|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0070124"(mitochondrial translational initiation)|interpro:IPR000178(Initiation factor 2)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR036925|interpro:IPR044145|rcsb pdb:6GAW|rcsb pdb:6GAZ|rcsb pdb:6GB2|rcsb pdb:6RW5|reactome:R-HSA-5368286|ensembl:ENSG00000085760(gene)|ensembl:ENST00000263629(transcript)|ensembl:ENST00000394600(transcript)|ensembl:ENST00000403721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0032790"(ribosome disassembly)|refseq:NP_001005369.1|refseq:NP_002444.2|refseq:XP_011531173.1|refseq:NP_001307930.1|refseq:NP_001307931.1|refseq:NP_001307932.1|refseq:XP_005264392.1|refseq:XP_016859651.1|refseq:XP_016859652.1|dip:DIP-27596N - - - figure legend:Table 2, no 23|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:kClXFAtdU2CB5IfDfvI8H+CyNvQ694009 rogid:ThigwWzs0gInoPjmmd8DYvyrWw49606 rigid:HbAGoCguUTrezul40Wi5/cdOBJI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80H93 uniprotkb:O75439 intact:EBI-25492924|uniprotkb:Q7TFA6 intact:EBI-721199|uniprotkb:O60416|uniprotkb:Q96FV4|ensembl:ENSP00000249269 psi-mi:ns8b_sars(display_long)|uniprotkb:Accessory protein 8b(gene name synonym)|uniprotkb:Non-structural protein 8b(gene name synonym)|uniprotkb:8b(orf name) psi-mi:mppb_human(display_long)|uniprotkb:Beta-MPP(gene name synonym)|uniprotkb:P-52(gene name synonym)|uniprotkb:PMPCB(gene name)|psi-mi:PMPCB(display_short)|uniprotkb:MPPB(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377331|imex:IM-28441-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0042025"(host cell nucleus)|interpro:IPR022722|reactome:R-HSA-9679504|refseq:NP_849177.1 refseq:NP_004270.2|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0017087"(mitochondrial processing peptidase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR037718|mint:O75439|reactome:R-HSA-1268020|reactome:R-HSA-8949664|ensembl:ENSG00000105819(gene)|ensembl:ENST00000249269(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion) - - - figure legend:Table 2, no 23|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:kClXFAtdU2CB5IfDfvI8H+CyNvQ694009 rogid:TMqHDYssMbBpUdw0HcGrMPaJd/89606 rigid:HbAGoCguUTrezul40Wi5/cdOBJI false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:P35813 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-989143|uniprotkb:O75551|uniprotkb:B5BU11|uniprotkb:J3KNM0|ensembl:ENSP00000378514 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:ppm1a_human(display_long)|uniprotkb:Protein phosphatase 2C isoform alpha(gene name synonym)|uniprotkb:PPM1A(gene name)|psi-mi:PPM1A(display_short)|uniprotkb:PPPM1A(gene name synonym)|uniprotkb:Protein phosphatase IA(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:XP_011535181.1|refseq:XP_011535180.1|refseq:NP_066283.1|refseq:NP_808820.1|refseq:NP_808821.2|refseq:XP_011535182.1|refseq:XP_011535183.1|refseq:XP_011535184.1|refseq:XP_011535185.1|refseq:XP_011535186.1|refseq:XP_005267836.1|refseq:XP_005267838.1|refseq:XP_016876873.1|refseq:XP_016876874.1|refseq:XP_016876875.1|refseq:XP_016876876.1|ensembl:ENSG00000100614(gene)|ensembl:ENST00000395076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0010991"(negative regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR012911(Protein serine/threonine phosphatase 2C, C-terminal)|interpro:IPR036457|interpro:IPR036580|mint:P35813|rcsb pdb:1A6Q|rcsb pdb:3FXJ|rcsb pdb:3FXK|rcsb pdb:3FXM|rcsb pdb:3FXO|rcsb pdb:4RA2|rcsb pdb:4RAF|rcsb pdb:4RAG|rcsb pdb:6B67|rcsb pdb:3FXL|reactome:R-HSA-2173795|reactome:R-HSA-380972 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:6Bhsr96yCyS7GN3SgN64RrNJTWk9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:O95229 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q6NSI4 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-8634209|ensembl:ENSP00000361628|uniprotkb:Q9H7W5|uniprotkb:Q6PHY5|uniprotkb:Q6PII9|intact:MINT-8162145|uniprotkb:Q9NWA6|uniprotkb:Q5JQS1|uniprotkb:Q4G0L7|uniprotkb:H7BY89|uniprotkb:Q5JRF9|uniprotkb:Q6PJU8 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:radx_human(display_long)|uniprotkb:RADX(gene name)|psi-mi:RADX(display_short)|uniprotkb:CXorf57(gene name synonym)|uniprotkb:RPA-related and RAD51-antagonist, X-chromosome(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 ensembl:ENSG00000147231(gene)|ensembl:ENST00000372548(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005657"(replication fork)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0016607"(nuclear speck)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR040893|refseq:NP_060485.4|refseq:NP_001171711.1 - - comment:mint figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:pUlTaH5Wq19LDuJp7qGlWFpa0q09606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q9UNE7 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:h4QyIM0TptgkQppPUgiKn68XjP49606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q9UL15 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q9UHD1 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q9P0L2 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-968587|uniprotkb:Q2HIY1|uniprotkb:Q5VTF9|uniprotkb:Q5VTG0|uniprotkb:Q96SW9|uniprotkb:Q9P251|uniprotkb:D3DTB0|uniprotkb:D3DTB1|ensembl:ENSP00000355884 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:mark1_human(display_long)|uniprotkb:MARK1(gene name)|psi-mi:MARK1(display_short)|uniprotkb:KIAA1477(gene name synonym)|uniprotkb:MARK(gene name synonym)|uniprotkb:MAP/microtubule affinity-regulating kinase 1(gene name synonym)|uniprotkb:PAR1 homolog c(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_001273057.1|refseq:NP_061120.3|ensembl:ENSP00000355884|ensembl:ENST00000366918|ensembl:ENSP00000355885|dip:DIP-39777N|ensembl:ENSG00000116141(gene)|ensembl:ENST00000366917(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033627|mint:Q9P0L2|rcsb pdb:2HAK|rcsb pdb:3OSE|rcsb pdb:6C9D - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:/ydFAiGjuUcmwDHO4tEPSSMlVjY9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q8NBA8 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-20218988|ensembl:ENSP00000425048|uniprotkb:J3KND6 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:dtwd2_human(display_long)|uniprotkb:DTWD2(gene name)|psi-mi:DTWD2(display_short)|uniprotkb:DTW domain-containing protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_775937.1|ensembl:ENSG00000169570(gene)|ensembl:ENST00000510708(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0016432"(tRNA-uridine aminocarboxypropyltransferase activity)|interpro:IPR005636(DTW)|interpro:IPR039262|refseq:NP_001295010.1 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:g6JkvzG9BuZWla+KUp9md98bWLE9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q7KZI7 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|dip:DIP-31321N|ensembl:ENSG00000072518(gene)|ensembl:ENST00000402010(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001764"(neuron migration)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q7KZF4 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q15013 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-712181|ensembl:ENSP00000361244|uniprotkb:B4DLV3|uniprotkb:Q6IBB1|uniprotkb:E9PAT7 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:md2bp_human(display_long)|uniprotkb:Caught by MAD2 protein(gene name synonym)|uniprotkb:MAD2L1BP(gene name)|psi-mi:MAD2L1BP(display_short)|uniprotkb:CMT2(gene name synonym)|uniprotkb:KIAA0110(gene name synonym)|uniprotkb:"p31(comet)"(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_001003690.1|refseq:NP_055443.1|ensembl:ENSG00000124688(gene)|ensembl:ENST00000372171(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR009511(MAD2L1 binding protein)|rcsb pdb:2QYF|rcsb pdb:6F0X|dip:DIP-34492N - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:LDtsULnHHfO9LVyGU4PtVTvF/OE9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q14192 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-701903|ensembl:ENSP00000322909|ensembl:ENSP00000344266|ensembl:ENSP00000377020|ensembl:ENSP00000377021|ensembl:ENSP00000386633|ensembl:ENSP00000386665|ensembl:ENSP00000386892|ensembl:ENSP00000433567|uniprotkb:Q13229|uniprotkb:Q13644|uniprotkb:Q9P294|uniprotkb:Q2I5I4|uniprotkb:Q5TM15 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:fhl2_human(display_long)|uniprotkb:Skeletal muscle LIM-protein 3(gene name synonym)|uniprotkb:LIM domain protein DRAL(gene name synonym)|uniprotkb:FHL2(gene name)|psi-mi:FHL2(display_short)|uniprotkb:DRAL(gene name synonym)|uniprotkb:SLIM3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 ensembl:ENSG00000115641(gene)|ensembl:ENST00000322142(transcript)|ensembl:ENST00000344213(transcript)|ensembl:ENST00000393352(transcript)|ensembl:ENST00000393353(transcript)|ensembl:ENST00000408995(transcript)|ensembl:ENST00000409177(transcript)|ensembl:ENST00000409807(transcript)|ensembl:ENST00000530340(transcript)|refseq:NP_001034581.1|refseq:NP_001441.4|refseq:NP_963849.1|refseq:NP_963851.2|refseq:NP_001305823.1|refseq:NP_001305824.1|refseq:NP_001305825.1|refseq:NP_001305826.1|refseq:XP_011509100.1|dip:DIP-5980N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009725"(response to hormone)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR037987|mint:Q14192|rcsb pdb:1X4K|rcsb pdb:1X4L|rcsb pdb:2D8Z|rcsb pdb:2MIU|reactome:R-HSA-1989781 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:4X5kI037ASzuT1zACXH89BkwDBk9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q13643 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:Q00341 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-1049478|uniprotkb:Q9UCY3|uniprotkb:Q53QU2|uniprotkb:B4DTQ2|uniprotkb:E7EM71|intact:EBI-28974616|ensembl:ENSP00000399139 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:vigln_human(display_long)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)|uniprotkb:HDLBP(gene name)|psi-mi:HDLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:VGL(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 ensembl:ENSP00000399139|refseq:NP_005327.1|refseq:NP_976221.1|refseq:NP_001230829.1|refseq:XP_011509360.1|refseq:XP_011509362.1|refseq:XP_016859429.1|ensembl:ENSG00000115677(gene)|ensembl:ENST00000427183(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0045296"(cadherin binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|rcsb pdb:1VIG|rcsb pdb:1VIH|rcsb pdb:2CTE|rcsb pdb:2CTF|rcsb pdb:2CTJ|rcsb pdb:2CTK|rcsb pdb:2CTL|rcsb pdb:2CTM|reactome:R-HSA-8964011|refseq:NP_001307894.1|refseq:NP_001307895.1|refseq:XP_005247059.2|refseq:XP_006712538.1|refseq:XP_005247060.2 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:4NqKFEjUn5Fi5Ws3tirpanGqYwg9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:P43686 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:P27448 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413(gene)|ensembl:ENST00000429436(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033628|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7O94|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:O94826 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59636 uniprotkb:O95817 intact:EBI-9021274|uniprotkb:Q7T6R2 intact:EBI-747185|uniprotkb:Q3B763|uniprotkb:Q9NT20|uniprotkb:Q9P120|uniprotkb:A8K5L8|ensembl:ENSP00000358081 psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:bag3_human(display_long)|uniprotkb:Bcl-2-associated athanogene 3(gene name synonym)|uniprotkb:Bcl-2-binding protein Bis(gene name synonym)|uniprotkb:Docking protein CAIR-1(gene name synonym)|uniprotkb:BAG3(gene name)|psi-mi:BAG3(display_short)|uniprotkb:BIS(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377343|imex:IM-28441-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 refseq:NP_004272.2|ensembl:ENSG00000151929(gene)|ensembl:ENST00000369085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007420"(brain development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0021510"(spinal cord development)|go:"GO:0030018"(Z disc)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773|mint:O95817|reactome:R-HSA-3371453|go:"GO:0101031"(chaperone complex)|dip:DIP-41273N - - - figure legend:Table 2, no 24|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rogid:Ld26VRSMJghXG/U98A76RijSDBc9606 rigid:ZoNUrX45JysD7OI2mxH0hj74zAs false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9Y276 intact:EBI-25488942 intact:EBI-719257|uniprotkb:B3KTW9|uniprotkb:Q7Z2V7|ensembl:ENSP00000352219|ensembl:ENSP00000375957|ensembl:ENSP00000375958|ensembl:ENSP00000375959|ensembl:ENSP00000404999|ensembl:ENSP00000406494|ensembl:ENSP00000413908 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:bcs1_human(display_long)|uniprotkb:BCS1-like protein(gene name synonym)|uniprotkb:BCS1L(gene name)|psi-mi:BCS1L(display_short)|uniprotkb:BCS1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_001073335.1|refseq:NP_004319.1|ensembl:ENSG00000074582(gene)|ensembl:ENST00000359273(transcript)|ensembl:ENST00000392109(transcript)|ensembl:ENST00000392110(transcript)|ensembl:ENST00000392111(transcript)|ensembl:ENST00000412366(transcript)|ensembl:ENST00000431802(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR014851(BCS1 N terminal)|interpro:IPR027417|reactome:R-HSA-1268020|ensembl:ENST00000439945(transcript)|refseq:NP_001244271.1|refseq:NP_001244272.1|refseq:NP_001244273.1|refseq:NP_001305765.1|refseq:NP_001307646.1|refseq:XP_006712741.1|refseq:XP_016860120.1|refseq:XP_016860121.1 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:NMfoX75THfvFwzpgBcpKXGmRGcM9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9UL03 intact:EBI-25488942 intact:EBI-1381827|uniprotkb:Q0P664|uniprotkb:Q6PJP4|uniprotkb:Q9UFK0|uniprotkb:Q9Y5M9|ensembl:ENSP00000310260 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:int6_human(display_long)|uniprotkb:INTS6(gene name)|psi-mi:INTS6(display_short)|uniprotkb:DBI1(gene name synonym)|uniprotkb:DDX26(gene name synonym)|uniprotkb:DDX26A(gene name synonym)|uniprotkb:DBI-1(gene name synonym)|uniprotkb:Protein deleted in cancer 1(gene name synonym)|uniprotkb:Protein DDX26(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_001035026.1|refseq:NP_001035027.1|refseq:NP_036273.1|refseq:NP_001293020.1|refseq:XP_011533342.1|dip:DIP-38627N|ensembl:ENSG00000102786(gene)|ensembl:ENST00000311234(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR029307|interpro:IPR036465|mint:Q9UL03|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:J+sAm/TQd5WHkUw80k7UmX0TSyg9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9UH62 intact:EBI-25488942 intact:EBI-717832|uniprotkb:Q53HC6|uniprotkb:Q7LCF5|uniprotkb:Q9NPE4|ensembl:ENSP00000340672|ensembl:ENSP00000439032|ensembl:ENSP00000454483 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:armx3_human(display_long)|uniprotkb:ARM protein lost in epithelial cancers on chromosome X 3(gene name synonym)|uniprotkb:ARMCX3(gene name)|psi-mi:ARMCX3(display_short)|uniprotkb:ALEX3(gene name synonym)|uniprotkb:BM-017(orf name)|uniprotkb:UNQ2517/PRO6007(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_057691.1|refseq:NP_808816.1|refseq:NP_808817.1|refseq:XP_005262198.1|ensembl:ENSG00000102401(gene)|ensembl:ENST00000341189(transcript)|ensembl:ENST00000471229(transcript)|ensembl:ENST00000537169(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000225(Armadillo)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-9013404 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:Svmu819cxCJThLvYapRMLQpAszw9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9P2E5 intact:EBI-25488942 intact:EBI-11733862|ensembl:ENSP00000035307|uniprotkb:B2DBD8|uniprotkb:Q6P2I4|uniprotkb:Q6UXD2 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:chpf2_human(display_long)|uniprotkb:CHPF2(gene name)|psi-mi:CHPF2(display_short)|uniprotkb:CHSY3(gene name synonym)|uniprotkb:CSGLCAT(gene name synonym)|uniprotkb:KIAA1402(gene name synonym)|uniprotkb:CSGlcA-T(gene name synonym)|uniprotkb:Chondroitin glucuronyltransferase(gene name synonym)|uniprotkb:Chondroitin polymerizing factor 2(gene name synonym)|uniprotkb:Chondroitin synthase 3(gene name synonym)|uniprotkb:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase(gene name synonym)|uniprotkb:UNQ299/PRO339(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000033100(gene)|ensembl:ENST00000035307(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0008376"(acetylgalactosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0047238"(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)|go:"GO:0050510"(N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity)|interpro:IPR008428(Chondroitin N-acetylgalactosaminyltransferase)|reactome:R-HSA-2022870|refseq:NP_061888.1 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:8b6T33i9aZO/Af6lE6TxbbvuxBg9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9NXK8 intact:EBI-25488942 intact:EBI-719790|uniprotkb:Q9H5K4|uniprotkb:B3KSJ8|ensembl:ENSP00000247977 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:fxl12_human(display_long)|uniprotkb:F-box and leucine-rich repeat protein 12(gene name synonym)|uniprotkb:F-box protein FBL12(gene name synonym)|uniprotkb:FBXL12(gene name)|psi-mi:FBXL12(display_short)|uniprotkb:FBL12(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_060173.1|refseq:NP_001303865.1|refseq:NP_001303866.1|refseq:NP_001303867.1|refseq:NP_001303868.1|refseq:NP_001303869.1|refseq:NP_001303870.1|refseq:NP_001303871.1|ensembl:ENSG00000127452(gene)|ensembl:ENST00000247977(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|mint:Q9NXK8|reactome:R-HSA-8951664|reactome:R-HSA-983168 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:b+3vZLMbZvEww+hdTa3YnLkPiC49606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9NU22 intact:EBI-25488942 intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol) - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9NT22 intact:EBI-25488942 intact:EBI-3197883|ensembl:ENSP00000332806|uniprotkb:Q495S6|uniprotkb:Q495S7|uniprotkb:Q76KT4|uniprotkb:Q495S5 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:emil3_human(display_long)|uniprotkb:EMILIN3(gene name)|psi-mi:EMILIN3(display_short)|uniprotkb:C20orf130(gene name synonym)|uniprotkb:EMILIN5(gene name synonym)|uniprotkb:EMILIN-5(gene name synonym)|uniprotkb:Elastin microfibril interface-located protein 3(gene name synonym)|uniprotkb:Elastin microfibril interface-located protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENST00000332312(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0042802"(identical protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR011489(EMI)|reactome:R-HSA-2129379|ensembl:ENSG00000183798(gene)|refseq:NP_443078.1 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:2qdJvA52a/LCMpXMS7bPFXg+f4U9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9NSE4 intact:EBI-25488942 intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9NRD5 intact:EBI-25488942 intact:EBI-79165|uniprotkb:O95906|ensembl:ENSP00000349465|ensembl:ENSP00000385205|intact:EBI-2622151|uniprotkb:B3KS52 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:pick1_human(display_long)|uniprotkb:PICK1(gene name)|psi-mi:PICK1(display_short)|uniprotkb:PRKCABP(gene name synonym)|uniprotkb:Protein kinase C-alpha-binding protein(gene name synonym)|uniprotkb:Protein interacting with C kinase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000100151(gene)|ensembl:ENST00000356976(transcript)|ensembl:ENST00000404072(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|refseq:NP_001034672.1|refseq:NP_001034673.1|refseq:NP_036539.1|go:"GO:0015844"(monoamine transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021782"(glial cell development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043113"(receptor clustering)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|interpro:IPR036034|interpro:IPR037959|mint:Q9NRD5|rcsb pdb:2GZV|rcsb pdb:6AR4|rcsb pdb:6BJN|rcsb pdb:6BJO|reactome:R-HSA-202733|reactome:R-HSA-416993 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:qRx+eNG7We8Oe0SQOekqpJpn8zk9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9H8K7 intact:EBI-25488942 intact:EBI-714785|uniprotkb:Q0P6C6|uniprotkb:Q8N597|ensembl:ENSP00000419126 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:paat_human(display_long)|uniprotkb:PAAT(gene name)|psi-mi:PAAT(display_short)|uniprotkb:C10orf88(gene name synonym)|uniprotkb:Protein associated with ABC transporters(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000119965(gene)|ensembl:ENST00000481909(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR028043|refseq:NP_079218.2 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:FVQBSowK05RlKodgqYZ71aHgU689606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9H4Z3 intact:EBI-25488942 intact:EBI-5235470|uniprotkb:E1P5P1|uniprotkb:Q54AB9|uniprotkb:Q9NT85|intact:EBI-28969183|ensembl:ENSP00000361486 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:capam_human(display_long)|uniprotkb:PCIF1(gene name)|psi-mi:PCIF1(display_short)|uniprotkb:C20orf67(gene name synonym)|uniprotkb:CAPAM(gene name synonym)|uniprotkb:PPP1R121(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 121(gene name synonym)|uniprotkb:Cap-specific adenosine methyltransferase(gene name synonym)|uniprotkb:Phosphorylated CTD-interacting factor 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSP00000361486|refseq:XP_011527282.1|refseq:XP_011527283.1|refseq:NP_071387.1|refseq:XP_016883502.1|ensembl:ENSG00000100982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016422"("mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity")|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0080009"(mRNA methylation)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR022035|interpro:IPR029048|interpro:IPR036020|interpro:IPR039881|mint:Q9H4Z3|rcsb pdb:2JX8|rcsb pdb:6IRV|rcsb pdb:6IRW|ensembl:ENST00000372409(transcript) - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:/LiqBpGc2Jxe9TaCJfYzM4oz/GM9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q9C0C7 intact:EBI-25488942 intact:EBI-2512975|ensembl:ENSP00000415327|ensembl:ENSP00000508322|uniprotkb:Q86XD6|uniprotkb:A6XN33|uniprotkb:Q9NXE7|uniprotkb:Q9H8Z0|intact:EBI-2556181|uniprotkb:D3DQP8|uniprotkb:G3V193 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:amra1_human(display_long)|uniprotkb:AMBRA1(gene name)|psi-mi:AMBRA1(display_short)|uniprotkb:DCAF3(gene name synonym)|uniprotkb:DDB1- and CUL4-associated factor 3(gene name synonym)|uniprotkb:KIAA1736(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000110497(gene)|ensembl:ENST00000458649(transcript)|ensembl:ENST00000683756(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|reactome:R-HSA-1632852|refseq:NP_001287660.1|refseq:NP_060219.2|refseq:NP_001254711.1|refseq:NP_001254712.1|refseq:XP_005253066.1|refseq:XP_005253068.1|refseq:XP_005253071.1|refseq:XP_006718322.1|dip:DIP-53597N - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:h4yD2iL711peDzI4kttngSdTLQk9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q96DF8 intact:EBI-25488942 intact:EBI-3928124|uniprotkb:Q49AH7|uniprotkb:Q9BTZ4|ensembl:ENSP00000252137 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:ess2_human(display_long)|uniprotkb:ESS2(gene name)|psi-mi:ESS2(display_short)|uniprotkb:DGCR13(gene name synonym)|uniprotkb:DGCR14(gene name synonym)|uniprotkb:DGSH(gene name synonym)|uniprotkb:DGSI(gene name synonym)|uniprotkb:DiGeorge syndrome critical region 13(gene name synonym)|uniprotkb:DiGeorge syndrome critical region 14(gene name synonym)|uniprotkb:DiGeorge syndrome protein H(gene name synonym)|uniprotkb:ES2(gene name synonym)|uniprotkb:Protein ES2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000100056(gene)|ensembl:ENST00000252137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR019148|ensembl:ENSP00000252137|refseq:NP_073210.1 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:4FNOVEs4KXbqLkXlGksstSsL2qs9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q8N2G8 intact:EBI-25488942 intact:EBI-10985637|uniprotkb:B4DQS4|uniprotkb:E9PDB5|uniprotkb:Q9BXM6|ensembl:ENSP00000301671|ensembl:ENSP00000467585 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:ghdc_human(display_long)|uniprotkb:GHDC(gene name)|psi-mi:GHDC(display_short)|uniprotkb:D11LGP1E(gene name synonym)|uniprotkb:LGP1(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_001136095.1|refseq:NP_115873.1|ensembl:ENSG00000167925(gene)|ensembl:ENST00000301671(transcript)|ensembl:ENST00000587427(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016881"(acid-amino acid ligase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|interpro:IPR004993(GH3 auxin-responsive promoter)|reactome:R-HSA-6798695 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:AlZkawSGl/YLF3onfXtqK0vWf4k9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q7Z3B4 intact:EBI-25488942 intact:EBI-741048|uniprotkb:Q96EA7|uniprotkb:Q9NVL5|uniprotkb:Q9P0I1|uniprotkb:B2RCK7|intact:EBI-10966427|uniprotkb:B4DT35|ensembl:ENSP00000264883 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:nup54_human(display_long)|uniprotkb:54 kDa nucleoporin(gene name synonym)|uniprotkb:NUP54(gene name)|psi-mi:NUP54(display_short) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_059122.2|refseq:NP_001265532.1|ensembl:ENSG00000138750(gene)|ensembl:ENST00000264883(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006605"(protein targeting)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR024864|interpro:IPR025712|interpro:IPR040985|mint:Q7Z3B4|rcsb pdb:4JNU|rcsb pdb:4JNV|rcsb pdb:4JO7|rcsb pdb:4JO9|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:/X2b8J20uRh86bEeCc1tJSRuaIM9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q6NUM9 intact:EBI-25488942 intact:EBI-11723756|uniprotkb:A6NIK3|uniprotkb:Q53R95|uniprotkb:Q53SA9|uniprotkb:Q6UX05|uniprotkb:Q8N2H5|uniprotkb:Q96FA4|uniprotkb:Q9NXE5|ensembl:ENSP00000295802 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:retst_human(display_long)|uniprotkb:RETSAT(gene name)|psi-mi:RETSAT(display_short)|uniprotkb:PPSIG(gene name synonym)|uniprotkb:UNQ439/PRO872(orf name)|uniprotkb:All-trans-13,14-dihydroretinol saturase(gene name synonym)|uniprotkb:PPAR-alpha-regulated and starvation-induced gene protein(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_060220.3|ensembl:ENSG00000042445(gene)|ensembl:ENST00000295802(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0051786"(all-trans-retinol 13,14-reductase activity)|interpro:IPR036188|reactome:R-HSA-975634 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:LWaHP0k+YymwKjS40faGMX9aNSs9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q5T4S7 intact:EBI-25488942 intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:8Iown8oj965YAir+95+3om5+1YM9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q5JSJ4 intact:EBI-25488942 intact:EBI-1104862|ensembl:ENSP00000359788|uniprotkb:Q5CZA2|uniprotkb:Q6IPS3|uniprotkb:Q6ZTU5|uniprotkb:Q6ZWE4 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:int6l_human(display_long)|uniprotkb:INTS6L(gene name)|psi-mi:INTS6L(display_short)|uniprotkb:DDX26B(gene name synonym)|uniprotkb:Protein DDX26B(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000165359(gene)|ensembl:ENST00000370752(transcript)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR029307|interpro:IPR036465|refseq:NP_872346.3 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:vi68m9WC6FezoCQV9ivvgmpzCOY9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:Q15067 intact:EBI-25488942 intact:EBI-3048535|ensembl:ENSP00000301608|uniprotkb:Q15101|uniprotkb:Q16131|uniprotkb:Q9UD31|uniprotkb:Q12863|uniprotkb:Q15068|uniprotkb:Q7Z3W5|uniprotkb:A8K6X8|uniprotkb:A8KAA0|uniprotkb:B4DK61|uniprotkb:F5GYQ8 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:acox1_human(display_long)|uniprotkb:ACOX1(gene name)|psi-mi:ACOX1(display_short)|uniprotkb:ACOX(gene name synonym)|uniprotkb:Palmitoyl-CoA oxidase(gene name synonym)|uniprotkb:Straight-chain acyl-CoA oxidase(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000161533(gene)|ensembl:ENST00000301608(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0003997"(acyl-CoA oxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016401"(palmitoyl-CoA oxidase activity)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071949"(FAD binding)|go:"GO:0140493"(very long-chain fatty acid beta-oxidation)|interpro:IPR002655(Acyl-CoA oxidase, C-terminal)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR012258(Acyl-CoA oxidase)|interpro:IPR029320|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR034171|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-1989781|reactome:R-HSA-2046106|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500|refseq:NP_001171968.1|refseq:NP_004026.2|refseq:NP_009223.2 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:nmFzdfUulW0CSpRLqXcetLzLvwk9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:P28340 intact:EBI-25488942 intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:P27540 intact:EBI-25488942 intact:EBI-80809|uniprotkb:C4AMA1|ensembl:ENSP00000351407|uniprotkb:B2R9H1|uniprotkb:F8WAP6|uniprotkb:Q59ED4|uniprotkb:Q5QP39|uniprotkb:Q8NDC7 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:arnt_human(display_long)|uniprotkb:ARNT(gene name)|psi-mi:ARNT(display_short)|uniprotkb:Dioxin receptor, nuclear translocator(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym)|uniprotkb:BHLHE2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000143437(gene)|ensembl:ENST00000358595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0016604"(nuclear body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045821"(positive regulation of glycolytic process)|refseq:NP_001184254.1|refseq:NP_001659.1|refseq:NP_848514.1|refseq:NP_001272964.1|refseq:NP_001272965.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:P27540|rcsb pdb:1D7G|rcsb pdb:1X0O|rcsb pdb:2A24|rcsb pdb:2ARN|rcsb pdb:2B02|rcsb pdb:2HV1|rcsb pdb:2K7S|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6X21|rcsb pdb:3H82|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|rcsb pdb:4EQ1|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4H6J|rcsb pdb:4LPZ|rcsb pdb:4PKY|rcsb pdb:4XT2|reactome:R-HSA-1234158|rcsb pdb:5TBM|reactome:R-HSA-1989781|reactome:R-HSA-211945|rcsb pdb:5UFP|reactome:R-HSA-211976|reactome:R-HSA-211981|rcsb pdb:5V0L|rcsb pdb:6CZW|reactome:R-HSA-8937144|ensembl:ENST00000354396|ensembl:ENSP00000346372|ensembl:ENSP00000351407|ensembl:ENST00000505755|ensembl:ENSP00000427571|ensembl:ENST00000515192|ensembl:ENSP00000423851|refseq:XP_016856778.1|dip:DIP-30886N - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:MAYVa32fLDGxgEr0VL9ZVg/EcIA9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:O95295 intact:EBI-25488942 intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7TLC7 uniprotkb:B2RTY4 intact:EBI-25488942 intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250 psi-mi:y14_sars(display_long)|uniprotkb:ORF14(orf name) psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26377368|imex:IM-28441-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|interpro:IPR035113 refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424 - - - figure legend:Table 2, no 25|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:neeKhbgFBkd1lYQvsZHB0OOs+lk694009 rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606 rigid:6YJBOO6o3pbbvNah/sRiVtB6oiQ false strep tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0DTD2 uniprotkb:O94826 intact:EBI-25475909 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-26377557|imex:IM-28441-150|wwpdb:7KDT|emdb:EMD-22829 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 - - - figure legend:Table S8|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2020/10/16 2020/10/21 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rigid:pL0h9yf058XhKWpu8aKMi2gNDzA false - sufficient binding region:109-608 - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:O94826 uniprotkb:P0DTD2 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 intact:EBI-25475909 psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26384641|imex:IM-28441-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 - - - figure legend:6C|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rigid:pL0h9yf058XhKWpu8aKMi2gNDzA false - strep tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94826 uniprotkb:P59636 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 intact:EBI-9021274|uniprotkb:Q7T6R2 psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26384670|imex:IM-28441-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 - - - figure legend:6C|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2020/10/21 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rigid:hQQA+d/d/D6pAXCUUwQFDaCH5Jc false - strep tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0DTC8 uniprotkb:Q96F46 intact:EBI-25475900 intact:EBI-5591258|uniprotkb:O43844|uniprotkb:Q20WK1|ensembl:ENSP00000320936 psi-mi:ns8_sars2(display_long)|uniprotkb:Non-structural protein 8(gene name synonym)|uniprotkb:8(orf name) psi-mi:i17ra_human(display_long)|uniprotkb:IL17RA(gene name)|psi-mi:IL17RA(display_short)|uniprotkb:IL17R(gene name synonym)|uniprotkb:CDw217(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26427565|imex:IM-28441-168 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0042802"(identical protein binding)|go:"GO:0044174"(host cell endosome)|interpro:IPR044391|interpro:IPR022722|refseq:YP_009724396.1|rcsb pdb:7JTL|rcsb pdb:7JX6 refseq:NP_055154.3|refseq:NP_001276834.1|reactome:R-HSA-448424|ensembl:ENSG00000177663(gene)|ensembl:ENST00000319363(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009615"(response to virus)|go:"GO:0030368"(interleukin-17 receptor activity)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0045087"(innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0072537"(fibroblast activation)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:2000340"("positive regulation of chemokine (C-X-C motif) ligand 1 production")|interpro:IPR013568(SEFIR)|interpro:IPR032356|interpro:IPR038683|interpro:IPR039465|interpro:IPR043046|rcsb pdb:3JVF|rcsb pdb:4HSA|rcsb pdb:4NUX|rcsb pdb:5N9B|rcsb pdb:5NAN - - - figure legend:8B|comment:"Interaction of SARS-CoV-2 Orf8 with IL17RA (Uniprot Q16552) occurs with or without additional IL-17A treatment."|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/16 2022/01/11 rogid:ewwYrFNyPZ3iELR/bcvfB2DfU3Q2697049 rogid:5qXoQilp6J+JgOi5gpj8i0QTgCk9606 rigid:uU4DB6tNinkhS9BkjvPBaEFCYh4 false strep tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P0DTD2 uniprotkb:O94826 intact:EBI-25475909 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-26385016|imex:IM-28441-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 - - - figure legend:Figure 6D|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2020/10/16 2020/10/21 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rigid:pL0h9yf058XhKWpu8aKMi2gNDzA false - sufficient binding region:109-608 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O94826 uniprotkb:P0DTD2 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 intact:EBI-25475909 psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:"MI:0663"(confocal microscopy) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-26386279|imex:IM-28441-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 - - - figure legend:6E|comment:We found SARS-CoV-1 and SARS-CoV-2 Orf9b expressed in HeLaM cells co-localized with Tom70.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-helam)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells, HelaM variant cell line) - 2020/10/16 2020/10/21 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rigid:pL0h9yf058XhKWpu8aKMi2gNDzA false - strep tag:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:O94826 uniprotkb:P59636 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 intact:EBI-9021274|uniprotkb:Q7T6R2 psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-26386491|imex:IM-28441-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 - - - figure legend:6E|comment:We found SARS-CoV-1 and SARS-CoV-2 Orf9b expressed in HeLaM cells co-localized with Tom70.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-helam)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells, HelaM variant cell line) - 2020/10/16 2020/10/21 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rigid:hQQA+d/d/D6pAXCUUwQFDaCH5Jc false - strep tag:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:O94826 uniprotkb:P0DTD2 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 intact:EBI-25475909 psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:"MI:0663"(confocal microscopy) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-26386465|imex:IM-28441-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 - - - figure legend:6G|comment:Orf9b was found to co-localize with Tom70 upon SARS-CoV-2 infection.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2020/10/16 2020/10/21 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rigid:pL0h9yf058XhKWpu8aKMi2gNDzA false - strep tag:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:O94826 uniprotkb:P0DTD2 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 intact:EBI-25475909 psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:orf9b_sars2(display_long)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26387629|imex:IM-28441-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 rcsb pdb:7DHG|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|interpro:IPR018542|interpro:IPR037223|rcsb pdb:6Z4U|rcsb pdb:7KDT|reactome:R-HSA-9694676 - - - figure legend:Supp. Figure 19A|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2020/10/16 2020/10/21 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rogid:4eszLp/bYgk5FnuoFGjWpI2D9v82697049 rigid:pL0h9yf058XhKWpu8aKMi2gNDzA false - strep tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94826 uniprotkb:P59636 intact:EBI-2800236|uniprotkb:D3DN48|ensembl:ENSP00000284320 intact:EBI-9021274|uniprotkb:Q7T6R2 psi-mi:tom70_human(display_long)|uniprotkb:TOMM70(gene name)|psi-mi:TOMM70(display_short)|uniprotkb:KIAA0719(gene name synonym)|uniprotkb:TOM70(gene name synonym)|uniprotkb:TOMM70A(gene name synonym)|uniprotkb:Translocase of outer membrane 70 kDa subunit(gene name synonym)|uniprotkb:Translocase of outer mitochondrial membrane protein 70(gene name synonym)|uniprotkb:Mitochondrial precursor proteins import receptor(gene name synonym) psi-mi:orf9b_sars(display_long)|uniprotkb:Protein 9b(gene name synonym)|uniprotkb:9b(orf name)|uniprotkb:Accessory protein 9b(gene name synonym)|uniprotkb:ORF-9b(gene name synonym) psi-mi:"MI:0096"(pull down) Gordon et al. (2020) imex:IM-28441|pubmed:33060197 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26387623|imex:IM-28441-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055635.3|ensembl:ENSG00000154174(gene)|ensembl:ENST00000284320(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098586"(cellular response to virus)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O94826|rcsb pdb:7DHG|rcsb pdb:7KDT|go:"GO:0005741"(mitochondrial outer membrane)|reactome:R-HSA-168928|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-1268020 reactome:R-HSA-9679504|refseq:NP_828859.1|go:"GO:0016020"(membrane)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044162"(host cell cytoplasmic vesicle membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044423"(virion component)|interpro:IPR018542|rcsb pdb:2CME|interpro:IPR037223 - - - figure legend:Supp. Figure 19A|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-a_549)|taxid:9606(Homo sapiens Caucasian lung carcinoma cell line) - 2020/10/16 2020/10/21 rogid:LtRXcptMA0w6Pv/4lksPfPJ4CYY9606 rogid:ZEzTkfwAYVAO0h/WLJJYeWYudyk694009 rigid:hQQA+d/d/D6pAXCUUwQFDaCH5Jc false - strep tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)