#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0DTD1-PRO_0000449628 uniprotkb:P0DTD1-PRO_0000449628 intact:EBI-25475880 intact:EBI-25475880 psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0071"(molecular sieving) Rogstam et al. (2020) imex:IM-28450|pubmed:33036230 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-26428591|imex:IM-28450-1|wwpdb:2fyg - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) - chain-seq-start:4254|chain-seq-end:4392 chain-seq-start:4254|chain-seq-end:4392 figure legend:2A, Supp. Figure 2|comment:One major and one minor peak were observed. These peaks most likely correspond to monomeric and dimeric nsp10. The results showed that after long-term storage at high concentration, aggregates form, and the amount of dimers increases substantially.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2020/10/13 2020/10/23 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rigid:CeLYgaNHrnZUOpT7+PQVAc0xthY false sufficient binding region:10-132 sufficient binding region:10-132 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0DTD1-PRO_0000449628 uniprotkb:P0DTD1-PRO_0000449628 intact:EBI-25475880 intact:EBI-25475880 psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p0dtd1-pro_0000449628(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0028"(cosedimentation in solution) Rogstam et al. (2020) imex:IM-28450|pubmed:33036230 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-26428673|imex:IM-28450-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) intact:EBI-25492095(chain-parent)|uniprotkb:P0DTD1(chain-parent) - chain-seq-start:4254|chain-seq-end:4392 chain-seq-start:4254|chain-seq-end:4392 figure legend:2 B/C, Table S3|comment:The predominant species is consistent with the theoretical molecular weight of monomeric nsp10. The second-most-populous species is consistent with dimeric nsp10. There was no evidence of oligomeric states higher than dimers in freshly prepared nsp10.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2020/10/13 2020/10/23 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rogid:L4eD+20oc1IdNFJ9By3H2uun6L02697049 rigid:CeLYgaNHrnZUOpT7+PQVAc0xthY false sufficient binding region:10-132 sufficient binding region:10-132 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)