#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BPU9 uniprotkb:Q9NXB0 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-719269|uniprotkb:Q96G13|uniprotkb:Q284T0|uniprotkb:B7WNX4|uniprotkb:F5H885|ensembl:ENSP00000376827 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:mks1_human(display_long)|uniprotkb:MKS1(gene name)|psi-mi:MKS1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Okazaki et al. (2020) pubmed:32726168|imex:IM-28464 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435431|imex:IM-28464-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2 refseq:NP_001159399.1|refseq:NP_060247.2|refseq:NP_001308197.1|refseq:NP_001308198.1|refseq:XP_016880294.1|dip:DIP-56251N|ensembl:ENSG00000011143(gene)|ensembl:ENST00000393119(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990403"(embryonic brain development)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-HSA-5610787|reactome:R-HSA-5620912|go:"GO:0044458"(motile cilium assembly) - comment:mint - figure legend:Fig. 1A, Supp.Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/29 2020/10/29 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:jKX0egBpJwPvOwirWteGtSJvARg9606 rigid:ZwnwiXk9tb4bPyxEup30JI06Z1c false enhanced green fluorescent protein tag:c-c mcherry fluorescent protein tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9BPU9 uniprotkb:Q9UPM9 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-372535|uniprotkb:Q9BU22|ensembl:ENSP00000261499 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:b9d1_human(display_long)|uniprotkb:B9D1(gene name)|psi-mi:B9D1(display_short)|uniprotkb:MKS1-related protein 1(gene name synonym)|uniprotkb:MKSR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Okazaki et al. (2020) pubmed:32726168|imex:IM-28464 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435439|imex:IM-28464-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2 refseq:NP_056496.1|ensembl:ENSG00000108641(gene)|ensembl:ENST00000261499(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001944"(vasculature development)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008158"(hedgehog receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0060563"(neuroepithelial cell differentiation)|interpro:IPR010796(B9)|reactome:R-HSA-5620912|go:"GO:0043010"(camera-type eye development)|refseq:NP_001308145.1|refseq:NP_001308147.1|refseq:NP_001308148.1|refseq:XP_016879941.1 - comment:mint - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/29 2020/10/29 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:tNjqpSLN+C226jR/+vqujaE3sk09606 rigid:iLPXSm5mFj2n1m2Xyr2McZswp00 false enhanced green fluorescent protein tag:c-c mcherry fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9BPU9 uniprotkb:Q9NXB0 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-719269|uniprotkb:Q96G13|uniprotkb:Q284T0|uniprotkb:B7WNX4|uniprotkb:F5H885|ensembl:ENSP00000376827 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:mks1_human(display_long)|uniprotkb:MKS1(gene name)|psi-mi:MKS1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Okazaki et al. (2020) pubmed:32726168|imex:IM-28464 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435447|imex:IM-28464-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2 refseq:NP_001159399.1|refseq:NP_060247.2|refseq:NP_001308197.1|refseq:NP_001308198.1|refseq:XP_016880294.1|dip:DIP-56251N|ensembl:ENSG00000011143(gene)|ensembl:ENST00000393119(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990403"(embryonic brain development)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-HSA-5610787|reactome:R-HSA-5620912|go:"GO:0044458"(motile cilium assembly) - comment:mint - figure legend:Fig. 1A, 1C.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/29 2020/10/29 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:jKX0egBpJwPvOwirWteGtSJvARg9606 rigid:ZwnwiXk9tb4bPyxEup30JI06Z1c false mcherry fluorescent protein tag:c-c enhanced green fluorescent protein tag:n-n|sufficient binding region:290-559 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9BPU9 uniprotkb:Q9UPM9 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-372535|uniprotkb:Q9BU22|ensembl:ENSP00000261499 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:b9d1_human(display_long)|uniprotkb:B9D1(gene name)|psi-mi:B9D1(display_short)|uniprotkb:MKS1-related protein 1(gene name synonym)|uniprotkb:MKSR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Okazaki et al. (2020) pubmed:32726168|imex:IM-28464 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435455|imex:IM-28464-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2 refseq:NP_056496.1|ensembl:ENSG00000108641(gene)|ensembl:ENST00000261499(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001944"(vasculature development)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008158"(hedgehog receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0060563"(neuroepithelial cell differentiation)|interpro:IPR010796(B9)|reactome:R-HSA-5620912|go:"GO:0043010"(camera-type eye development)|refseq:NP_001308145.1|refseq:NP_001308147.1|refseq:NP_001308148.1|refseq:XP_016879941.1 - comment:mint - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/29 2020/10/29 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:tNjqpSLN+C226jR/+vqujaE3sk09606 rigid:iLPXSm5mFj2n1m2Xyr2McZswp00 false mcherry fluorescent protein tag:c-c enhanced green fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NXB0 uniprotkb:Q9BPU9 intact:EBI-719269|uniprotkb:Q96G13|uniprotkb:Q284T0|uniprotkb:B7WNX4|uniprotkb:F5H885|ensembl:ENSP00000376827 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 psi-mi:mks1_human(display_long)|uniprotkb:MKS1(gene name)|psi-mi:MKS1(display_short) psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Okazaki et al. (2020) pubmed:32726168|imex:IM-28464 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435481|imex:IM-28464-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159399.1|refseq:NP_060247.2|refseq:NP_001308197.1|refseq:NP_001308198.1|refseq:XP_016880294.1|dip:DIP-56251N|ensembl:ENSG00000011143(gene)|ensembl:ENST00000393119(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990403"(embryonic brain development)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-HSA-5610787|reactome:R-HSA-5620912|go:"GO:0044458"(motile cilium assembly) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2 - - comment:mint figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/29 2020/10/29 rogid:jKX0egBpJwPvOwirWteGtSJvARg9606 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rigid:BvMW/iN62BoNYcDPEi4NZnxObsE false enhanced green fluorescent protein tag:n-n|sufficient binding region:290-559 fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9NXB0 uniprotkb:Q9UPM9 intact:EBI-719269|uniprotkb:Q96G13|uniprotkb:Q284T0|uniprotkb:B7WNX4|uniprotkb:F5H885|ensembl:ENSP00000376827 intact:EBI-372535|uniprotkb:Q9BU22|ensembl:ENSP00000261499 psi-mi:mks1_human(display_long)|uniprotkb:MKS1(gene name)|psi-mi:MKS1(display_short) psi-mi:b9d1_human(display_long)|uniprotkb:B9D1(gene name)|psi-mi:B9D1(display_short)|uniprotkb:MKS1-related protein 1(gene name synonym)|uniprotkb:MKSR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Okazaki et al. (2020) pubmed:32726168|imex:IM-28464 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435481|imex:IM-28464-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159399.1|refseq:NP_060247.2|refseq:NP_001308197.1|refseq:NP_001308198.1|refseq:XP_016880294.1|dip:DIP-56251N|ensembl:ENSG00000011143(gene)|ensembl:ENST00000393119(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990403"(embryonic brain development)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-HSA-5610787|reactome:R-HSA-5620912|go:"GO:0044458"(motile cilium assembly) refseq:NP_056496.1|ensembl:ENSG00000108641(gene)|ensembl:ENST00000261499(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001944"(vasculature development)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008158"(hedgehog receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0060563"(neuroepithelial cell differentiation)|interpro:IPR010796(B9)|reactome:R-HSA-5620912|go:"GO:0043010"(camera-type eye development)|refseq:NP_001308145.1|refseq:NP_001308147.1|refseq:NP_001308148.1|refseq:XP_016879941.1 - - - figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/29 2020/10/29 rogid:jKX0egBpJwPvOwirWteGtSJvARg9606 rogid:tNjqpSLN+C226jR/+vqujaE3sk09606 rigid:BvMW/iN62BoNYcDPEi4NZnxObsE false enhanced green fluorescent protein tag:n-n|sufficient binding region:290-559 mcherry fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9BPU9 uniprotkb:Q9NXB0 intact:EBI-6958971|ensembl:ENSP00000243578|ensembl:ENSP00000501911|intact:MINT-3060220 intact:EBI-719269|uniprotkb:Q96G13|uniprotkb:Q284T0|uniprotkb:B7WNX4|uniprotkb:F5H885|ensembl:ENSP00000376827 psi-mi:b9d2_human(display_long)|uniprotkb:B9D2(gene name)|psi-mi:B9D2(display_short)|uniprotkb:MKS1-related protein 2(gene name synonym)|uniprotkb:MKSR2(gene name synonym) psi-mi:mks1_human(display_long)|uniprotkb:MKS1(gene name)|psi-mi:MKS1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Okazaki et al. (2020) pubmed:32726168|imex:IM-28464 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435471|imex:IM-28464-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525651.1|ensembl:ENSG00000123810(gene)|ensembl:ENST00000243578(transcript)|ensembl:ENST00000675972(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR010796(B9)|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_085055.2 refseq:NP_001159399.1|refseq:NP_060247.2|refseq:NP_001308197.1|refseq:NP_001308198.1|refseq:XP_016880294.1|dip:DIP-56251N|ensembl:ENSG00000011143(gene)|ensembl:ENST00000393119(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003271"(smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016020"(membrane)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061009"(common bile duct development)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990403"(embryonic brain development)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010796(B9)|reactome:R-HSA-5610787|reactome:R-HSA-5620912|go:"GO:0044458"(motile cilium assembly) - comment:mint - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/29 2020/10/29 rogid:wvBU/yARiiNolCEtb5J82QzXiOQ9606 rogid:jKX0egBpJwPvOwirWteGtSJvARg9606 rigid:ZwnwiXk9tb4bPyxEup30JI06Z1c false mcherry fluorescent protein tag:c-c enhanced green fluorescent protein tag:n-n|sufficient binding region:290-559 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)