#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0DTC1-PRO_0000449636 uniprotkb:P24468 intact:EBI-25762407 intact:EBI-2795198|uniprotkb:B6ZGU1|uniprotkb:Q03754|uniprotkb:B4DQJ2|uniprotkb:Q3KQR7|ensembl:ENSP00000377721 psi-mi:p0dtc1-pro_0000449636(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:cot2_human(display_long)|uniprotkb:NR2F2(gene name)|psi-mi:NR2F2(display_short)|uniprotkb:ARP1(gene name synonym)|uniprotkb:TFCOUP2(gene name synonym)|uniprotkb:COUP transcription factor II(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group F member 2(gene name synonym)|uniprotkb:Apolipoprotein A-I regulatory protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762295|imex:IM-28206-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_066285.1|refseq:NP_001138627.1|refseq:NP_001138628.1|refseq:NP_001138629.1|ensembl:ENSG00000185551(gene)|ensembl:ENST00000394166(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008585"(female gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0009956"(radial pattern formation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032355"(response to estradiol)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060173"(limb development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:3CJW|reactome:R-HSA-381340|dip:DIP-29713N - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:XsZyqUr06sQQaD3oXAA3IEa6Dug9606 rigid:S95DFDdxLDm6Qb1eGyRwZMZWkng false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449636 uniprotkb:Q14165 intact:EBI-25762407 intact:EBI-1046466|ensembl:ENSP00000228506 psi-mi:p0dtc1-pro_0000449636(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:mlec_human(display_long)|uniprotkb:MLEC(gene name)|psi-mi:MLEC(display_short)|uniprotkb:KIAA0152(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762295|imex:IM-28206-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000110917(gene)|ensembl:ENST00000228506(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0035579"(specific granule membrane)|interpro:IPR021720|interpro:IPR039155|rcsb pdb:6S7T|reactome:R-HSA-532668|reactome:R-HSA-6798695|refseq:NP_055545.1 - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:bEjayZ3by/oF+uvxqdw2r69ab2k9606 rigid:S95DFDdxLDm6Qb1eGyRwZMZWkng false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449636 uniprotkb:P56270-2 intact:EBI-25762407 intact:EBI-12068586|ensembl:ENSP00000219782 psi-mi:p0dtc1-pro_0000449636(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:p56270-2(display_long)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)|uniprotkb:Pur-1(gene name synonym)|uniprotkb:Purine-binding transcription factor(gene name synonym)|uniprotkb:Serum amyloid A-activating factor-1(gene name synonym)|uniprotkb:Transcription factor Zif87(gene name synonym)|uniprotkb:ZF87(gene name synonym)|uniprotkb:ZNF801(gene name synonym)|uniprotkb:Zinc finger protein 801(gene name synonym)|uniprotkb:SAF-2(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762295|imex:IM-28206-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) intact:EBI-1809742(isoform-parent)|uniprotkb:P56270-2(isoform-parent)|ensembl:ENSG00000103495(gene)|ensembl:ENST00000219782(transcript) - chain-seq-start:181|chain-seq-end:818 isoform-comment:May act as a dominant negative of isoform 1. Reduced expression during inflammatory conditions. figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:FXVTXAr6TsS+nf6iumslhyzqACc9606 rigid:S95DFDdxLDm6Qb1eGyRwZMZWkng false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449636 uniprotkb:P11021 intact:EBI-25762407 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:p0dtc1-pro_0000449636(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762295|imex:IM-28206-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 rigid:S95DFDdxLDm6Qb1eGyRwZMZWkng false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449636 uniprotkb:P85037-1 intact:EBI-25762407 intact:EBI-6259436|ensembl:ENSP00000328720 psi-mi:p0dtc1-pro_0000449636(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:p85037-1(display_long)|uniprotkb:a(isoform synonym)|uniprotkb:FOXK1(gene name)|psi-mi:FOXK1(display_short)|uniprotkb:MNF(gene name synonym)|uniprotkb:Myocyte nuclear factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762295|imex:IM-28206-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000164916(gene)|ensembl:ENST00000328914(transcript)|intact:EBI-2509974(isoform-parent) - chain-seq-start:181|chain-seq-end:818 isoform-comment:No experimental confirmation available. figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:ngoE3oNlIDGkTf1ZMYG4OQ6lvE09606 rigid:S95DFDdxLDm6Qb1eGyRwZMZWkng false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449636 uniprotkb:Q5VV42 intact:EBI-25762407 intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695|ensembl:ENSP00000367873 psi-mi:p0dtc1-pro_0000449636(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762295|imex:IM-28206-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_060244.2|ensembl:ENSG00000145996(gene)|ensembl:ENST00000274695(transcript)|ensembl:ENST00000378610(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315 - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:lcVR7toGJEEaapbjgZzL5rz1ivc2697049 rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606 rigid:S95DFDdxLDm6Qb1eGyRwZMZWkng false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q9UJZ1 intact:EBI-25474098 intact:EBI-1044428|ensembl:ENSP00000348886|uniprotkb:O60376|uniprotkb:Q53G29|uniprotkb:Q96FY2|uniprotkb:Q9P042|uniprotkb:D3DRN3|uniprotkb:B4E1K7 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:stml2_human(display_long)|uniprotkb:EPB72-like protein 2(gene name synonym)|uniprotkb:STOML2(gene name)|psi-mi:STOML2(display_short)|uniprotkb:SLP2(gene name synonym)|uniprotkb:HSPC108(orf name)|uniprotkb:Paraprotein target 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000165283(gene)|ensembl:ENST00000356493(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q9UJZ1|reactome:R-HSA-8949664|refseq:NP_001273960.1|refseq:NP_038470.1|refseq:NP_001273961.1 - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:VH6uT4ShPg3IpPHbQtaSVXjZAYg9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q9Y657 intact:EBI-25474098 intact:EBI-727129|uniprotkb:Q7KZJ8|uniprotkb:Q9GZT2|uniprotkb:Q9H0N7|uniprotkb:A8K0X6|uniprotkb:B3KRQ4|ensembl:ENSP00000365019 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:spin1_human(display_long)|uniprotkb:Ovarian cancer-related protein(gene name synonym)|uniprotkb:SPIN1(gene name)|psi-mi:SPIN1(display_short)|uniprotkb:OCR(gene name synonym)|uniprotkb:SPIN(gene name synonym)|uniprotkb:Spindlin1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_006708.2|ensembl:ENSG00000106723(gene)|ensembl:ENST00000375859(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029565|interpro:IPR042567|mint:Q9Y657|rcsb pdb:2NS2|rcsb pdb:4H75|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:5JSG|rcsb pdb:5JSJ|rcsb pdb:5Y5W|rcsb pdb:6I8B|rcsb pdb:6I8L|rcsb pdb:6I8Y|rcsb pdb:6QPL|rcsb pdb:7BQZ|rcsb pdb:7BU9|rcsb pdb:7CNA|dip:DIP-40062N - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:OY/wCdms/yjDXj5aY2QffHXXXUY9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q96K19 intact:EBI-25474098 intact:EBI-2130336|uniprotkb:Q7Z483|uniprotkb:Q86YC0|uniprotkb:Q8N2B5|uniprotkb:Q8N5G9|uniprotkb:Q8NG30|uniprotkb:Q9H0V6|uniprotkb:Q8IXR7|uniprotkb:D3DSY6|uniprotkb:E9PIL4|ensembl:ENSP00000434797|ensembl:ENSP00000445725 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rn170_human(display_long)|uniprotkb:RNF170(gene name)|psi-mi:RNF170(display_short)|uniprotkb:Putative LAG1-interacting protein(gene name synonym)|uniprotkb:RING finger protein 170(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF170(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:XP_011542968.1|refseq:NP_001153695.1|refseq:NP_001153696.1|refseq:NP_112216.3|refseq:XP_016869370.1|refseq:XP_016869371.1|refseq:XP_006716467.1|refseq:NP_001153697.1|ensembl:ENSG00000120925(gene)|ensembl:ENST00000527424(transcript)|ensembl:ENST00000534961(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR010652(Protein of unknown function DUF1232)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR038896 - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:8pLW38LjT6M3terF644Qlt7ur5o9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q99623 intact:EBI-25474098 intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1 - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:h4pib54mBeQgOKCe/hib58LM26w9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:P35232 intact:EBI-25474098 intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948 - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q9UBN7-1 intact:EBI-25474098 intact:EBI-25762318|ensembl:ENSP00000334061|ensembl:ENSP00000365804|ensembl:ENSP00000496013|ensembl:ENSP00000496046 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q9ubn7-1(display_long)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym)|uniprotkb:JM21(orf name)|uniprotkb:HDAC6p131(isoform synonym)|uniprotkb:HDAC6(gene name)|psi-mi:HDAC6(display_short)|uniprotkb:KIAA0901(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000094631(gene)|ensembl:ENST00000334136(transcript)|ensembl:ENST00000376619(transcript)|ensembl:ENST00000643374(transcript)|ensembl:ENST00000644068(transcript)|intact:EBI-301697(isoform-parent) - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:j4lt2D2ZcySF9FFqSlCo3a+Q3VU9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:Q6Y7W6-1 intact:EBI-25474098 intact:EBI-25762361|ensembl:ENSP00000362664|ensembl:ENSP00000386537 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q6y7w6-1(display_long)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) intact:EBI-765394(isoform-parent)|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript) - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O94905-1 intact:EBI-25474098 intact:EBI-25762371|ensembl:ENSP00000428112 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:o94905-1(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|intact:EBI-4400770(isoform-parent) - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O75477 intact:EBI-25474098 intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1 - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:O60573 intact:EBI-25474098 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000037310 uniprotkb:P51798-1 intact:EBI-25474098 intact:EBI-25762380 psi-mi:p0c6x7-pro_0000037310(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:p51798-1(display_long)|uniprotkb:CLCN7(gene name)|psi-mi:CLCN7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762307|imex:IM-28206-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent) uniprotkb:P51798-1(isoform-parent) - chain-seq-start:181|chain-seq-end:818 - figure legend:2 C/D, Supp. Table 1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uSbjRz4rkYk4xCxFNKoeNwrWAcQ694009 rogid:ze820JsKN1GtxH/lcPnPWN78k1I9606 rigid:emGgU7mfIQQhTMGOomGBNmzGAjo false flag tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q8N4V1 intact:EBI-25762414 intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q9P0T4 intact:EBI-25762414 intact:EBI-745520|uniprotkb:B2RDM6|ensembl:ENSP00000270451|ensembl:ENSP00000466047|ensembl:ENSP00000466564 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:zn581_human(display_long)|uniprotkb:ZNF581(gene name)|psi-mi:ZNF581(display_short)|uniprotkb:HSPC189(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_057619.1|ensembl:ENSG00000171425(gene)|ensembl:ENST00000270451(transcript)|ensembl:ENST00000587252(transcript)|ensembl:ENST00000588537(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P0T4|go:"GO:0005634"(nucleus)|refseq:XP_006723303.1|refseq:XP_016882356.1 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:SpE0ZPhcfXB4PnyufoyWq4iNAs89606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q9BQB6-1 intact:EBI-25762414 intact:EBI-25762441|ensembl:ENSP00000378426 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:q9bqb6-1(display_long)|uniprotkb:VKORC1(gene name)|psi-mi:VKORC1(display_short)|uniprotkb:VKOR(gene name synonym)|uniprotkb:Vitamin K1 2,3-epoxide reductase subunit 1(gene name synonym)|uniprotkb:MSTP134(orf name)|uniprotkb:MSTP576(orf name)|uniprotkb:UNQ308/PRO351(orf name)|uniprotkb:MST576(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000167397(gene)|ensembl:ENST00000394975(transcript)|intact:EBI-6256462(isoform-parent) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:C3RrQ+y7Huai7PExa9LOvfqni+U9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P57088 intact:EBI-25762414 intact:EBI-1048629|uniprotkb:Q9H953|uniprotkb:B3KSS8|ensembl:ENSP00000422473|ensembl:ENSP00000427006|ensembl:ENSP00000441455 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:tmm33_human(display_long)|uniprotkb:Protein DB83(gene name synonym)|uniprotkb:TMEM33(gene name)|psi-mi:TMEM33(display_short)|uniprotkb:DB83(gene name synonym)|uniprotkb:SHINC-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_060596.2|refseq:XP_005248173.1|refseq:XP_005248174.1|ensembl:ENSG00000109133(gene)|ensembl:ENST00000325094(transcript)|ensembl:ENST00000504986(transcript)|ensembl:ENST00000513702(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061024"(membrane organization)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|mint:P57088 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:FGc4/gpnYoRtlDJMxQWh5hXe5Ko9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q99805 intact:EBI-25762414 intact:EBI-2852254|uniprotkb:Q2TAY5|uniprotkb:A8K399|ensembl:ENSP00000365567|ensembl:ENSP00000493515 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:tm9s2_human(display_long)|uniprotkb:TM9SF2(gene name)|psi-mi:TM9SF2(display_short)|uniprotkb:p76(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_004791.1|ensembl:ENSG00000125304(gene)|ensembl:ENST00000376387(transcript)|ensembl:ENST00000642475(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q99805 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:qg5QSnzX8+4H0Nfab7Ci9n9igc09606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q9BVV7 intact:EBI-25762414 intact:EBI-6570759|uniprotkb:Q9P010|ensembl:ENSP00000169551 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:tim21_human(display_long)|uniprotkb:TIMM21(gene name)|psi-mi:TIMM21(display_short)|uniprotkb:TIM21-like protein, mitochondrial(gene name synonym)|uniprotkb:HSPC154(orf name)|uniprotkb:C18orf55(gene name synonym)|uniprotkb:TIM21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000075336(gene)|ensembl:ENST00000169551(transcript)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR013261(Mitochondrial import inner membrane translocase, subunit Tim21)|interpro:IPR038552|reactome:R-HSA-1268020|refseq:NP_054896.2 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:/iiwo2Ow/n6nP6pWgf/QI/V8CNg9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:O15260-1 intact:EBI-25762414 intact:EBI-11613951|ensembl:ENSP00000361057|ensembl:ENSP00000486049 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:o15260-1(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000371989(transcript)|ensembl:ENST00000629578(transcript)|intact:EBI-1044848(isoform-parent) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q8TCJ2 intact:EBI-25762414 intact:EBI-2256290|uniprotkb:Q96JZ4|uniprotkb:Q96KY7|ensembl:ENSP00000295770 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:stt3b_human(display_long)|uniprotkb:STT3B(gene name)|psi-mi:STT3B(display_short)|uniprotkb:SIMP(gene name synonym)|uniprotkb:Source of immunodominant MHC-associated peptides homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_849193.1|ensembl:ENSG00000163527(gene)|ensembl:ENST00000295770(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034998"(oligosaccharyltransferase I complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:Q8TCJ2|rcsb pdb:6S7T - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:4F+9LbIZTFRoczuphd1jzuhnFDo9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q92504 intact:EBI-25762414 intact:EBI-1051105|uniprotkb:Q5STP8|uniprotkb:Q9UIQ0|uniprotkb:B0UXF6|ensembl:ENSP00000363807|ensembl:ENSP00000363809|ensembl:ENSP00000372700|ensembl:ENSP00000372701|ensembl:ENSP00000389623|ensembl:ENSP00000391735|ensembl:ENSP00000403583|ensembl:ENSP00000407093|ensembl:ENSP00000410656|ensembl:ENSP00000413027|ensembl:ENSP00000414145|ensembl:ENSP00000416439 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:s39a7_human(display_long)|uniprotkb:Solute carrier family 39 member 7(gene name synonym)|uniprotkb:Histidine-rich membrane protein Ke4(gene name synonym)|uniprotkb:SLC39A7(gene name)|psi-mi:SLC39A7(display_short)|uniprotkb:HKE4(gene name synonym)|uniprotkb:RING5(gene name synonym)|uniprotkb:Zrt-, Irt-like protein 7(gene name synonym)|uniprotkb:Really interesting new gene 5 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_001070984.1|refseq:NP_008910.2|refseq:NP_001275706.1|ensembl:ENSG00000112473(gene)|ensembl:ENSG00000206288(gene)|ensembl:ENSG00000224399(gene)|ensembl:ENSG00000226614(gene)|ensembl:ENSG00000227402(gene)|ensembl:ENSG00000229802(gene)|ensembl:ENST00000374675(transcript)|ensembl:ENST00000374677(transcript)|ensembl:ENST00000383213(transcript)|ensembl:ENST00000383214(transcript)|ensembl:ENST00000416369(transcript)|ensembl:ENST00000418477(transcript)|ensembl:ENST00000423043(transcript)|ensembl:ENST00000441854(transcript)|ensembl:ENST00000441953(transcript)|ensembl:ENST00000443773(transcript)|ensembl:ENST00000456261(transcript)|ensembl:ENST00000431735(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR003689(Zinc/iron permease)|mint:Q92504|reactome:R-HSA-442380 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:br+gKDgDx3uyEg/kbJ6JCqJaTXA9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P62979 intact:EBI-25762414 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q99942 intact:EBI-25762414 intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q96AA3 intact:EBI-25762414 intact:EBI-6269616|ensembl:ENSP00000296292|uniprotkb:Q96J03 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:rft1_human(display_long)|uniprotkb:RFT1(gene name)|psi-mi:RFT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000163933(gene)|ensembl:ENST00000296292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034202"(glycolipid floppase activity)|go:"GO:0034203"(glycolipid translocation)|interpro:IPR007594(RFT1)|mint:Q96AA3|reactome:R-HSA-446193|reactome:R-HSA-4570571|refseq:NP_443091.1 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:off+uN6MYDiLT5q1oh7G2sd6RXw9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P78527 intact:EBI-25762414 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q8NC67 intact:EBI-25762414 intact:EBI-2829094|uniprotkb:Q9NVY8|uniprotkb:Q8ND51|uniprotkb:Q96SP4|uniprotkb:Q7Z381|ensembl:ENSP00000455169|uniprotkb:J3KNF1 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:neto2_human(display_long)|uniprotkb:NETO2(gene name)|psi-mi:NETO2(display_short)|uniprotkb:BTCL2(gene name synonym)|uniprotkb:Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2(gene name synonym)|uniprotkb:UNQ1926/PRO4401(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_001188406.1|refseq:NP_060562.3|ensembl:ENSG00000171208(gene)|ensembl:ENST00000562435(transcript)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:2000312"(regulation of kainate selective glutamate receptor activity)|interpro:IPR000859(CUB)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR023415|interpro:IPR028868|interpro:IPR035914|interpro:IPR036055 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:zYMe/vy3cmCbdG0CsP9t9WiHmf49606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q9H0U3 intact:EBI-25762414 intact:EBI-2798816|uniprotkb:Q6P577|uniprotkb:B2RAR4|uniprotkb:Q53G00|uniprotkb:Q8NBN6|uniprotkb:D3DTE3|ensembl:ENSP00000354649|ensembl:ENSP00000480732 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:magt1_human(display_long)|uniprotkb:IAG2(gene name synonym)|uniprotkb:Implantation-associated protein(gene name synonym)|uniprotkb:PSEC0084(orf name)|uniprotkb:UNQ628/PRO1244(orf name)|uniprotkb:MAGT1(gene name)|psi-mi:MAGT1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_115497.4|ensembl:ENSG00000102158(gene)|ensembl:ENST00000358075(transcript)|ensembl:ENST00000618282(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR006844(OST3/OST6)|interpro:IPR021149|interpro:IPR036249|mint:Q9H0U3|rcsb pdb:6S7T|reactome:R-HSA-446203|reactome:R-HSA-5223345|reactome:R-HSA-6798695|reactome:R-HSA-9694548|go:"GO:0050890"(cognition) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:M7/LTAlkuCCyeqlTlcJkfu2HU9k9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P36776-3 intact:EBI-25762414 intact:EBI-25762494|ensembl:ENSP00000441523 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:p36776-3(display_long)|uniprotkb:LONHs(gene name synonym)|uniprotkb:Lon protease-like protein(gene name synonym)|uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)|uniprotkb:LONP1(gene name)|psi-mi:LONP1(display_short)|uniprotkb:PRSS15(gene name synonym)|uniprotkb:Serine protease 15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000196365(gene)|ensembl:ENST00000540670(transcript)|intact:EBI-357448(isoform-parent) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:Smzd7f2mp91NLiCaLYtpw7BmBBE9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P11021 intact:EBI-25762414 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q96MM7 intact:EBI-25762414 intact:EBI-10981456|uniprotkb:Q6PIC4|uniprotkb:Q4VC07|uniprotkb:Q86SM9|uniprotkb:B9WRT5|uniprotkb:B9WRT4|uniprotkb:Q96SJ4|uniprotkb:Q8N3T4|uniprotkb:Q2TB13|uniprotkb:Q8NBN4|uniprotkb:E9PDY5|ensembl:ENSP00000359873|ensembl:ENSP00000384013 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:h6st2_human(display_long)|uniprotkb:HS6ST2(gene name)|psi-mi:HS6ST2(display_short)|uniprotkb:PSEC0092(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_001070656.1|refseq:NP_671704.3|refseq:XP_005262547.1|refseq:XP_011529708.1|refseq:XP_016885433.1|refseq:XP_016885434.1|ensembl:ENSG00000171004(gene)|ensembl:ENST00000370836(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0015015"(heparan sulfate proteoglycan biosynthetic process, enzymatic modification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017095"(heparan sulfate 6-O-sulfotransferase activity)|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|interpro:IPR010635(Heparan sulphate 6-sulphotransferase)|interpro:IPR027417|reactome:R-HSA-2022928|ensembl:ENST00000406696(transcript) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:RT5E9eyaRk49nCvVuisl/6Sje6A9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P30459 intact:EBI-25762414 intact:EBI-15259444|uniprotkb:O19647|uniprotkb:O43906|uniprotkb:O46874|uniprotkb:Q95IZ5|uniprotkb:Q9UIN1 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:1a74_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Aw-19(gene name synonym)|uniprotkb:Aw-74(gene name synonym)|uniprotkb:MHC class I antigen A*74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|ensembl:ENST00000454091|ensembl:ENSP00000410645|ensembl:ENSG00000223980|reactome:R-HSA-1236974|reactome:R-HSA-1236977|go:"GO:0030881"(beta-2-microglobulin binding)|reactome:R-HSA-198933|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0009986"(cell surface)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR036179|interpro:IPR037055 - chain-seq-start:2764|chain-seq-end:3263 no-uniprot-update: figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:PJ+lx+6+jWkYtS0ivsc13ct711I9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q15011-1 intact:EBI-25762414 intact:EBI-25762501 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:q15011-1(display_long)|uniprotkb:HERPUD1(gene name)|psi-mi:HERPUD1(display_short)|uniprotkb:HERP(gene name synonym)|uniprotkb:KIAA0025(gene name synonym)|uniprotkb:MIF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) uniprotkb:Q15011-1(isoform-parent) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:m0v4gj4HeJ8bPlD8V5X5UnItVpo9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q7L5D6 intact:EBI-25762414 intact:EBI-711823|uniprotkb:A4D2Q1|uniprotkb:B3KNC7|uniprotkb:Q9UFC9|uniprotkb:Q9Y309|ensembl:ENSP00000265857 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:get4_human(display_long)|uniprotkb:CEE(gene name synonym)|uniprotkb:Conserved edge-expressed protein(gene name synonym)|uniprotkb:GET4(gene name)|psi-mi:GET4(display_short)|uniprotkb:CGI-20(orf name)|uniprotkb:C7orf20(gene name synonym)|uniprotkb:TRC35(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 35 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000239857(gene)|ensembl:ENST00000265857(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0045048"(protein insertion into ER membrane)|go:"GO:0051087"(chaperone binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|interpro:IPR007317(Protein of unknown function DUF410)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q7L5D6|rcsb pdb:6AU8|reactome:R-HSA-9609523|refseq:NP_057033.2 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:WbZJTGrC2/fB4iOFLJYn9MIWZFA9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:O94905-1 intact:EBI-25762414 intact:EBI-25762371|ensembl:ENSP00000428112 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:o94905-1(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|intact:EBI-4400770(isoform-parent) - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:O75477 intact:EBI-25762414 intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P39656 intact:EBI-25762414 intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:Q9ULG6 intact:EBI-25762414 intact:EBI-2873893|intact:EBI-28979549|uniprotkb:Q8IYV8|uniprotkb:Q9BY53|uniprotkb:A0PJH3|uniprotkb:Q05DG4|uniprotkb:O14712|uniprotkb:Q5U5S7|uniprotkb:Q9HA17|uniprotkb:A8K9T0|ensembl:ENSP00000311656|ensembl:ENSP00000454456 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:ccpg1_human(display_long)|uniprotkb:CCPG1(gene name)|psi-mi:CCPG1(display_short)|uniprotkb:CCP8(gene name synonym)|uniprotkb:CPR8(gene name synonym)|uniprotkb:KIAA1254(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) ensembl:ENSP00000415128|ensembl:ENST00000442196|ensembl:ENSP00000403400|ensembl:ENSP00000454456|ensembl:ENST00000425574|refseq:NP_001191380.1|refseq:NP_004739.3|refseq:NP_065790.2|ensembl:ENSP00000311656|refseq:NP_001191379.1|ensembl:ENST00000310958(transcript)|ensembl:ENSG00000260916(gene)|ensembl:ENST00000569205(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033588|rcsb pdb:7D0E - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:jAMOJsrn4wr2TnlJzGyAyQp25989606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P27824 intact:EBI-25762414 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:O95816 intact:EBI-25762414 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0DTC1-PRO_0000449638 uniprotkb:P16615 intact:EBI-25762414 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:p0dtc1-pro_0000449638(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:2697049(SARS-CoV-2)|taxid:2697049(SARS-CoV-2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762396|imex:IM-28206-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25496252(chain-parent) refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N - chain-seq-start:2764|chain-seq-end:3263 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:uD0ZROWA14gCrmerlMfCjROCjz82697049 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 rigid:RqSf/ciqxHuAe7qUwSguk57puT0 false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q8N4V1 intact:EBI-25488721 intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:P62699 intact:EBI-25488721 intact:EBI-11721624|uniprotkb:D6W568|uniprotkb:Q65Z97|uniprotkb:Q8R174|uniprotkb:Q9D6M1|uniprotkb:Q9UMX7|uniprotkb:Q9Y3C9|ensembl:ENSP00000261353|ensembl:ENSP00000368834|ensembl:ENSP00000368835|ensembl:ENSP00000383974|ensembl:ENSP00000385278 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ypel5_human(display_long)|uniprotkb:YPEL5(gene name)|psi-mi:YPEL5(display_short)|uniprotkb:CGI-127(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001120871.1|refseq:NP_001120872.1|refseq:NP_001120873.1|refseq:NP_057145.1|ensembl:ENSG00000119801(gene)|ensembl:ENST00000261353(transcript)|ensembl:ENST00000379519(transcript)|ensembl:ENST00000379520(transcript)|ensembl:ENST00000402003(transcript)|ensembl:ENST00000402708(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030496"(midbody)|go:"GO:0046872"(metal ion binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034751|interpro:IPR039058|mint:P62699|reactome:R-HSA-6798695|refseq:XP_016859807.1|refseq:XP_016859808.1|refseq:XP_016859809.1|refseq:XP_016859810.1|refseq:XP_016859811.1 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:ZpDZwTkWSDPONRLnApZ8fKl/NHk9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9H7D7 intact:EBI-25488721 intact:EBI-1046864|uniprotkb:A0MNN3|uniprotkb:Q4G100|uniprotkb:Q59EC4|uniprotkb:Q5GLZ9|uniprotkb:Q86UY4|uniprotkb:Q9H3C2|ensembl:ENSP00000504428|intact:EBI-1642504 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wdr26_human(display_long)|uniprotkb:CUL4- and DDB1-associated WDR protein 2(gene name synonym)|uniprotkb:Myocardial ischemic preconditioning up-regulated protein 2(gene name synonym)|uniprotkb:WDR26(gene name)|psi-mi:WDR26(display_short)|uniprotkb:CDW2(gene name synonym)|uniprotkb:MIP2(gene name synonym)|uniprotkb:PRO0852(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9H7D7|ensembl:ENSG00000162923(gene)|ensembl:ENST00000678917(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|refseq:NP_001108585.2|refseq:NP_079436.4 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:HRA6f68aldUqB1rVa7uM9srSyR49606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9BQB6-1 intact:EBI-25488721 intact:EBI-25762441|ensembl:ENSP00000378426 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q9bqb6-1(display_long)|uniprotkb:VKORC1(gene name)|psi-mi:VKORC1(display_short)|uniprotkb:VKOR(gene name synonym)|uniprotkb:Vitamin K1 2,3-epoxide reductase subunit 1(gene name synonym)|uniprotkb:MSTP134(orf name)|uniprotkb:MSTP576(orf name)|uniprotkb:UNQ308/PRO351(orf name)|uniprotkb:MST576(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000167397(gene)|ensembl:ENST00000394975(transcript)|intact:EBI-6256462(isoform-parent) - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:C3RrQ+y7Huai7PExa9LOvfqni+U9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q99942 intact:EBI-25488721 intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9H871-1 intact:EBI-25488721 intact:EBI-25762560|ensembl:ENSP00000283632 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q9h871-1(display_long)|uniprotkb:RMND5A(gene name)|psi-mi:RMND5A(display_short)|uniprotkb:P44CTLH(gene name synonym)|uniprotkb:Protein RMD5 homolog A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000153561(gene)|ensembl:ENST00000283632(transcript)|intact:EBI-2797992(isoform-parent) - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:+wLGFpC1YJ1y6PVi15799YxByKI9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q96S59-1 intact:EBI-25488721 intact:EBI-25762579 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q96s59-1(display_long)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) uniprotkb:Q96S59-1(isoform-parent) - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q6VN20 intact:EBI-25488721 intact:EBI-310569|intact:EBI-1056526|uniprotkb:A4FTY2|uniprotkb:Q9P264|intact:EBI-10984753|ensembl:ENSP00000316589|uniprotkb:B4DID0|uniprotkb:B4DQH9|uniprotkb:E7EW27 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rbp10_human(display_long)|uniprotkb:RANBP10(gene name)|psi-mi:RANBP10(display_short)|uniprotkb:KIAA1464(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_065901.1|refseq:NP_001307167.1|refseq:NP_001307168.1|refseq:NP_001307169.1|ensembl:ENSG00000141084(gene)|ensembl:ENST00000317506(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q6VN20|reactome:R-HSA-8851805 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:DaNPLQf0T/+lsKrL+uhGtWXG0pI9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9UKZ9 intact:EBI-25488721 intact:EBI-20737478|ensembl:ENSP00000295992|uniprotkb:B2RCH9|uniprotkb:D3DNG4|uniprotkb:Q9BRH3 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:pcoc2_human(display_long)|uniprotkb:Procollagen COOH-terminal proteinase enhancer 2(gene name synonym)|uniprotkb:UNQ250/PRO287(orf name)|uniprotkb:PCOLCE2(gene name)|psi-mi:PCOLCE2(display_short)|uniprotkb:PCPE2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000163710(gene)|ensembl:ENST00000295992(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0008201"(heparin binding)|go:"GO:0016504"(peptidase activator activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000859(CUB)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|interpro:IPR035814|interpro:IPR035914|reactome:R-HSA-1650814|refseq:NP_037495.1 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:3AeMzMmBuXsnhhgACl/fG15meZQ9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:O75592-2 intact:EBI-25488721 intact:EBI-12503140 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:o75592-2(display_long)|uniprotkb:MYCBP2(gene name)|psi-mi:MYCBP2(display_short)|uniprotkb:KIAA0916(gene name synonym)|uniprotkb:Myc-binding protein 2(gene name synonym)|uniprotkb:PAM(gene name synonym)|uniprotkb:Protein associated with Myc(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) intact:EBI-1043774(isoform-parent)|uniprotkb:O75592-2(isoform-parent) - chain-seq-start:2741|chain-seq-end:3240 isoform-comment:Derived from EST data. figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:3Rs3RMw3itW8YGy7jvcT3tDSXEU9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9UL63-1 intact:EBI-25488721 intact:EBI-25762574 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q9ul63-1(display_long)|uniprotkb:MKLN1(gene name)|psi-mi:MKLN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) uniprotkb:Q9UL63-1(isoform-parent) - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:7yT0576+rLpdpgT/cqXPEuf80/g9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q7L5Y9-1 intact:EBI-25488721 intact:EBI-25762566 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q7l5y9-1(display_long)|uniprotkb:MAEA(gene name)|psi-mi:MAEA(display_short)|uniprotkb:EMP(gene name synonym)|uniprotkb:HLC10(orf name)|uniprotkb:PIG5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) uniprotkb:Q7L5Y9-1(isoform-parent) - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:8eoZgqL1bgRlGgQ3YiJDejdFWtk9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q13907 intact:EBI-25488721 intact:EBI-6285983|ensembl:ENSP00000401879|uniprotkb:B4E155|uniprotkb:Q32Q13|uniprotkb:Q53GQ6|uniprotkb:Q86U81|uniprotkb:Q8WUX8|uniprotkb:Q96IZ4|uniprotkb:Q9BQ74 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:idi1_human(display_long)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:Isopentenyl pyrophosphate isomerase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000067064(gene)|ensembl:ENST00000429642(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR015797(NUDIX)|mint:Q13907|rcsb pdb:2DHO|rcsb pdb:2I6K|rcsb pdb:2ICJ|rcsb pdb:2ICK|reactome:R-HSA-191273|reactome:R-HSA-2426168|refseq:NP_001304884.1|refseq:NP_001304885.1|refseq:NP_001304886.1|refseq:NP_004499.2|refseq:XP_011517759.1 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:UbjHfBd6yrV1Gxv+R0z56N7DVgA9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q15011-1 intact:EBI-25488721 intact:EBI-25762501 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q15011-1(display_long)|uniprotkb:HERPUD1(gene name)|psi-mi:HERPUD1(display_short)|uniprotkb:HERP(gene name synonym)|uniprotkb:KIAA0025(gene name synonym)|uniprotkb:MIF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) uniprotkb:Q15011-1(isoform-parent) - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:m0v4gj4HeJ8bPlD8V5X5UnItVpo9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9NWU2 intact:EBI-25488721 intact:EBI-1051077|uniprotkb:Q8N5M5|uniprotkb:E1P5I3|ensembl:ENSP00000266069 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:gid8_human(display_long)|uniprotkb:GID8(gene name)|psi-mi:GID8(display_short)|uniprotkb:C20orf11(gene name synonym)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym)|uniprotkb:TWA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_060366.1|ensembl:ENSG00000101193(gene)|ensembl:ENST00000266069(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9NWU2|rcsb pdb:7NSC - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:P0HsK72KT6OPKKw7lVSJ/FiY4CU9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:P0C2W1 intact:EBI-25488721 intact:EBI-2511355|ensembl:ENSP00000310332|uniprotkb:A6NF90|uniprotkb:D3DXB5 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:fbsp1_human(display_long)|uniprotkb:FBXO45(gene name)|psi-mi:FBXO45(display_short)|uniprotkb:FBX45(gene name synonym)|uniprotkb:F-box only protein 45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035784|interpro:IPR036047|interpro:IPR043136|ensembl:ENSG00000174013(gene)|ensembl:ENST00000311630(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021800"(cerebral cortex tangential migration)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060386"(synapse assembly involved in innervation)|go:"GO:0098978"(glutamatergic synapse)|refseq:NP_001099043.1 - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:dr+dGdYmjZoA/fo7CyxhmLyWRLM9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q9ULG6 intact:EBI-25488721 intact:EBI-2873893|intact:EBI-28979549|uniprotkb:Q8IYV8|uniprotkb:Q9BY53|uniprotkb:A0PJH3|uniprotkb:Q05DG4|uniprotkb:O14712|uniprotkb:Q5U5S7|uniprotkb:Q9HA17|uniprotkb:A8K9T0|ensembl:ENSP00000311656|ensembl:ENSP00000454456 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ccpg1_human(display_long)|uniprotkb:CCPG1(gene name)|psi-mi:CCPG1(display_short)|uniprotkb:CCP8(gene name synonym)|uniprotkb:CPR8(gene name synonym)|uniprotkb:KIAA1254(gene name synonym)|uniprotkb:Cell cycle progression restoration protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSP00000415128|ensembl:ENST00000442196|ensembl:ENSP00000403400|ensembl:ENSP00000454456|ensembl:ENST00000425574|refseq:NP_001191380.1|refseq:NP_004739.3|refseq:NP_065790.2|ensembl:ENSP00000311656|refseq:NP_001191379.1|ensembl:ENST00000310958(transcript)|ensembl:ENSG00000260916(gene)|ensembl:ENST00000569205(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033588|rcsb pdb:7D0E - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:jAMOJsrn4wr2TnlJzGyAyQp25989606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:P27824 intact:EBI-25488721 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X7-PRO_0000283841 uniprotkb:Q8IUR7-1 intact:EBI-25488721 intact:EBI-21199783|ensembl:ENSP00000419413 psi-mi:p0c6x7-pro_0000283841(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q8iur7-1(display_long)|uniprotkb:ARMC8(gene name)|psi-mi:ARMC8(display_short)|uniprotkb:S863-2(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762541|imex:IM-28206-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P0C6X7(chain-parent)|intact:EBI-7843867(chain-parent) ensembl:ENSG00000114098(gene)|ensembl:ENST00000469044(transcript)|intact:EBI-1049469(isoform-parent) - chain-seq-start:2741|chain-seq-end:3240 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/08/03 rogid:smPAOI1nAWgLZFomtwoLSa1N9vI694009 rogid:9QXdCIwU8zeZ94oQ7JJNDVD2NDk9606 rigid:cpBI3pyngApM2pcJEOAOWltjA8I false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:Q9Y605 intact:EBI-25762682 intact:EBI-995714|uniprotkb:B3KVT2|ensembl:ENSP00000318352|ensembl:ENSP00000372024|ensembl:ENSP00000422065|uniprotkb:D3DVT3 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_150638.1|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|ensembl:ENSG00000179010(gene)|ensembl:ENST00000320912(transcript)|ensembl:ENST00000382581(transcript)|ensembl:ENST00000507420(transcript)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001258982.1 - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:Q5T9L3 intact:EBI-25762682 intact:EBI-2868748|uniprotkb:Q8NC43|uniprotkb:Q7Z2Z9|uniprotkb:B2RNT2|intact:EBI-11046890|uniprotkb:Q5JRS7|ensembl:ENSP00000262348 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:wls_human(display_long)|uniprotkb:WLS(gene name)|psi-mi:WLS(display_short)|uniprotkb:C1orf139(gene name synonym)|uniprotkb:GPR177(gene name synonym)|uniprotkb:Integral membrane protein GPR177(gene name synonym)|uniprotkb:Protein evenness interrupted homolog(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 373(gene name synonym)|uniprotkb:UNQ85/PRO18667(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_001180263.1|refseq:NP_001002292.3|refseq:NP_079187.3|ensembl:ENSG00000116729(gene)|ensembl:ENST00000262348(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061355"(Wnt protein secretion)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR009551(Protein of unknown function DUF1171)|mint:Q5T9L3|rcsb pdb:7KC4|reactome:R-HSA-3238698|go:"GO:0070062"(extracellular exosome) - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:YRPwj0Ix8X5++/p3MVKVPm3viWs9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:Q9BQB6-1 intact:EBI-25762682 intact:EBI-25762441|ensembl:ENSP00000378426 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q9bqb6-1(display_long)|uniprotkb:VKORC1(gene name)|psi-mi:VKORC1(display_short)|uniprotkb:VKOR(gene name synonym)|uniprotkb:Vitamin K1 2,3-epoxide reductase subunit 1(gene name synonym)|uniprotkb:MSTP134(orf name)|uniprotkb:MSTP576(orf name)|uniprotkb:UNQ308/PRO351(orf name)|uniprotkb:MST576(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) ensembl:ENSG00000167397(gene)|ensembl:ENST00000394975(transcript)|intact:EBI-6256462(isoform-parent) - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:C3RrQ+y7Huai7PExa9LOvfqni+U9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:Q9BTV4 intact:EBI-25762682 intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625) - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:P57088 intact:EBI-25762682 intact:EBI-1048629|uniprotkb:Q9H953|uniprotkb:B3KSS8|ensembl:ENSP00000422473|ensembl:ENSP00000427006|ensembl:ENSP00000441455 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:tmm33_human(display_long)|uniprotkb:Protein DB83(gene name synonym)|uniprotkb:TMEM33(gene name)|psi-mi:TMEM33(display_short)|uniprotkb:DB83(gene name synonym)|uniprotkb:SHINC-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_060596.2|refseq:XP_005248173.1|refseq:XP_005248174.1|ensembl:ENSG00000109133(gene)|ensembl:ENST00000325094(transcript)|ensembl:ENST00000504986(transcript)|ensembl:ENST00000513702(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061024"(membrane organization)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|mint:P57088 - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:FGc4/gpnYoRtlDJMxQWh5hXe5Ko9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:P67812 intact:EBI-25762682 intact:EBI-1042500|uniprotkb:O75957|uniprotkb:P21378|uniprotkb:B4DUL4|uniprotkb:H0YK72|uniprotkb:H0YK83|uniprotkb:Q53FQ8|uniprotkb:B2RAD7|ensembl:ENSP00000268220 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:sc11a_human(display_long)|uniprotkb:SEC11A(gene name)|psi-mi:SEC11A(display_short)|uniprotkb:SPC18(gene name synonym)|uniprotkb:SPCS4A(gene name synonym)|uniprotkb:SEC11 homolog A(gene name synonym)|uniprotkb:SEC11-like protein 1(gene name synonym)|uniprotkb:Microsomal signal peptidase 18 kDa subunit(gene name synonym)|uniprotkb:Endopeptidase SP18(gene name synonym)|uniprotkb:SEC11L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_055115.1|ensembl:ENSG00000140612(gene)|ensembl:ENST00000268220(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019533|interpro:IPR019756|interpro:IPR019758|interpro:IPR036286|interpro:IPR037712|mint:P67812|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|go:"GO:0005787"(signal peptidase complex)|refseq:NP_001258847.1|refseq:NP_001258848.1|refseq:NP_001258849.1|refseq:NP_001258850.1|refseq:NP_001258851.1|dip:DIP-50359N - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:zaXzKdryO7BUa6mNJF2DsvIxIJU9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:Q99942 intact:EBI-25762682 intact:EBI-348482|ensembl:ENSP00000364235|ensembl:ENSP00000387879|ensembl:ENSP00000388795|ensembl:ENSP00000401172|ensembl:ENSP00000413131|ensembl:ENSP00000415127|ensembl:ENSP00000415784|uniprotkb:A2BFI6|uniprotkb:Q0VDB7|uniprotkb:Q9UMQ2|uniprotkb:B2R4K3 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:rnf5_human(display_long)|uniprotkb:RNF5(gene name)|psi-mi:RNF5(display_short)|uniprotkb:G16(gene name synonym)|uniprotkb:RING finger protein 5(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:NG2(gene name synonym)|uniprotkb:RMA1(gene name synonym)|uniprotkb:Ram1 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_008844.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031648"(protein destabilization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036503"(ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|ensembl:ENST00000456167(transcript)|ensembl:ENSG00000183574(gene)|ensembl:ENSG00000204308(gene)|ensembl:ENSG00000223767(gene)|ensembl:ENSG00000225452(gene)|ensembl:ENSG00000227277(gene)|ensembl:ENSG00000228405(gene)|ensembl:ENSG00000228907(gene)|ensembl:ENST00000375094(transcript)|ensembl:ENST00000413786(transcript)|ensembl:ENST00000432616(transcript)|ensembl:ENST00000445885(transcript)|ensembl:ENST00000449794(transcript)|ensembl:ENST00000453473(transcript)|go:"GO:0055085"(transmembrane transport)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-382556|reactome:R-HSA-5678895|reactome:R-HSA-901032|go:"GO:0044877"(protein-containing complex binding)|dip:DIP-29268N - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:eHlCD+xbWmpzFdhVn6OC5MPqeNE9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:Q9NZB2-1 intact:EBI-25762682 intact:EBI-5456305|ensembl:ENSP00000277165 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:q9nzb2-1(display_long)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym)|uniprotkb:Protein FAM120A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) intact:EBI-1171960(isoform-parent)|ensembl:ENSG00000048828(gene)|ensembl:ENST00000277165(transcript) - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:Q9UBM7 intact:EBI-25762682 intact:EBI-1054468|uniprotkb:O60492|uniprotkb:O60717|uniprotkb:B2R6Z2|ensembl:ENSP00000347717|ensembl:ENSP00000384739 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:dhcr7_human(display_long)|uniprotkb:"Sterol Delta(7)-reductase"(gene name synonym)|uniprotkb:DHCR7(gene name)|psi-mi:DHCR7(display_short)|uniprotkb:D7SR(gene name synonym)|uniprotkb:Delta7-sterol reductase(gene name synonym)|uniprotkb:Sterol reductase SR-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_001157289.1|refseq:NP_001351.2|mint:Q9UBM7|reactome:R-HSA-2426168|reactome:R-HSA-6807047|reactome:R-HSA-6807062|interpro:IPR018083|ensembl:ENSG00000172893(gene)|ensembl:ENST00000355527(transcript)|ensembl:ENST00000407721(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0009918"(sterol delta7 reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016132"(brassinosteroid biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0047598"(7-dehydrocholesterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein) - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:op53bBpGaOM0Ysy4Bn5q6qXcKgI9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:P39656 intact:EBI-25762682 intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548 - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:O14967 intact:EBI-25762682 intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967 - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:Akb2XoiNjob34njC2erE11yg80w9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P0C6X6-PRO_0000283829 uniprotkb:P27824 intact:EBI-25762682 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:p0c6x6-pro_0000283829(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Davies et al. (2020) imex:IM-28206|pubmed:32699849 taxid:31631(HCoV-OC43)|taxid:31631(Human coronavirus OC43) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25762549|imex:IM-28206-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25762605(chain-parent) refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - chain-seq-start:2751|chain-seq-end:3246 - figure legend:4, Supp. figure 5 B/C, Supp. Table 3|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/07/23 2020/07/24 rogid:2J7ihfUcyS5PCd60NKtVHsxgVRo31631 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rigid:Cs0+7lIAE0HhxNzRTkZjTXg/T1s false flag tag:c-c|tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology)