#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q03611	uniprotkb:Q03611	intact:EBI-20710167|ensemblmetazoa:ZC84.2.1|uniprotkb:P90800	intact:EBI-20710167|ensemblmetazoa:ZC84.2.1|uniprotkb:P90800	psi-mi:cng_caeel(display_long)|uniprotkb:Abnormal chemotaxis protein 4(gene name synonym)|uniprotkb:ZC84.2(orf name)|uniprotkb:tax-4(gene name)|psi-mi:tax-4(display_short)	psi-mi:cng_caeel(display_long)|uniprotkb:Abnormal chemotaxis protein 4(gene name synonym)|uniprotkb:ZC84.2(orf name)|uniprotkb:tax-4(gene name)|psi-mi:tax-4(display_short)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Zheng et al. (2020)	pubmed:32483338|imex:IM-28630	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26569176|imex:IM-28630-1|wwpdb:6WEL|emdb:EMD-21651	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-CEL-5620916|ensemblmetazoa:ZC84.2.1(transcript)|go:"GO:0003031"(detection of carbon dioxide)|go:"GO:0005222"(intracellular cAMP-activated cation channel activity)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007602"(phototransduction)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0009454"(aerotaxis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030553"(cGMP binding)|go:"GO:0034703"(cation channel complex)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040040"(thermosensory behavior)|ensemblmetazoa:WBGene00006526(gene)|go:"GO:0043052"(thermotaxis)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050907"(detection of chemical stimulus involved in sensory perception)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070482"(response to oxygen levels)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042048"(olfactory behavior)|refseq:NP_499033.1|rcsb pdb:5H3O|wormbase:ZC84.2|reactome:R-CEL-2485179|reactome:R-CEL-2514859|interpro:IPR032406|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR014710(RmlC-like jelly roll fold)|rcsb pdb:6WEJ|rcsb pdb:6WEK|rcsb pdb:6WEL	reactome:R-CEL-5620916|ensemblmetazoa:ZC84.2.1(transcript)|go:"GO:0003031"(detection of carbon dioxide)|go:"GO:0005222"(intracellular cAMP-activated cation channel activity)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007602"(phototransduction)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0009454"(aerotaxis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030553"(cGMP binding)|go:"GO:0034703"(cation channel complex)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040040"(thermosensory behavior)|ensemblmetazoa:WBGene00006526(gene)|go:"GO:0043052"(thermotaxis)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050907"(detection of chemical stimulus involved in sensory perception)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070482"(response to oxygen levels)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042048"(olfactory behavior)|refseq:NP_499033.1|rcsb pdb:5H3O|wormbase:ZC84.2|reactome:R-CEL-2485179|reactome:R-CEL-2514859|interpro:IPR032406|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR014710(RmlC-like jelly roll fold)|rcsb pdb:6WEJ|rcsb pdb:6WEK|rcsb pdb:6WEL	-	-	-	figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/12/20	2021/01/29	rogid:TkME5sarClA6pPM/JDFGXInjJ+I6239	rogid:TkME5sarClA6pPM/JDFGXInjJ+I6239	rigid:yRTGT5InNjTmhajr81MvO1PG1rE	false	mutation:403-403,407-407	mutation:403-403,407-407	4	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
chebi:"CHEBI:16356"	uniprotkb:Q03611	intact:EBI-8766547|chebi:"CHEBI:488479"|chebi:"CHEBI:1327"|chebi:"CHEBI:11675"|chebi:"CHEBI:14377"|chebi:"CHEBI:19829"	intact:EBI-20710167|ensemblmetazoa:ZC84.2.1|uniprotkb:P90800	psi-mi:3',5'-cyclic gmp(display_short)|psi-mi:"CHEBI:16356"(display_long)|intact:3',5'-Cyclic GMP(synonym)|intact:cGMP(synonym)|intact:Cyclic GMP(synonym)|intact:Guanosine 3',5'-cyclic monophosphate(synonym)|intact:Guanosine 3',5'-cyclic phosphate(synonym)|intact:Guanosine cyclic monophosphate(synonym)|intact:"guanosine 3',5'-(hydrogen phosphate)"(iupac name)	psi-mi:cng_caeel(display_long)|uniprotkb:Abnormal chemotaxis protein 4(gene name synonym)|uniprotkb:ZC84.2(orf name)|uniprotkb:tax-4(gene name)|psi-mi:tax-4(display_short)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Zheng et al. (2020)	pubmed:32483338|imex:IM-28630	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26984710|wwpdb:6wek|emdb:EMD-21650|imex:IM-28630-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	reactome:R-CEL-5620916|ensemblmetazoa:ZC84.2.1(transcript)|go:"GO:0003031"(detection of carbon dioxide)|go:"GO:0005222"(intracellular cAMP-activated cation channel activity)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007602"(phototransduction)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0009454"(aerotaxis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030553"(cGMP binding)|go:"GO:0034703"(cation channel complex)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040040"(thermosensory behavior)|ensemblmetazoa:WBGene00006526(gene)|go:"GO:0043052"(thermotaxis)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050907"(detection of chemical stimulus involved in sensory perception)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070482"(response to oxygen levels)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042048"(olfactory behavior)|refseq:NP_499033.1|rcsb pdb:5H3O|wormbase:ZC84.2|reactome:R-CEL-2485179|reactome:R-CEL-2514859|interpro:IPR032406|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR014710(RmlC-like jelly roll fold)|rcsb pdb:6WEJ|rcsb pdb:6WEK|rcsb pdb:6WEL	-	inchi key:ZOOGRGPOEVQQDX-UUOKFMHZSA-N	-	figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/12/20	2021/06/03	-	rogid:TkME5sarClA6pPM/JDFGXInjJ+I6239	-	false	-	-	4	4	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q03611	uniprotkb:Q03611	intact:EBI-20710167|ensemblmetazoa:ZC84.2.1|uniprotkb:P90800	intact:EBI-20710167|ensemblmetazoa:ZC84.2.1|uniprotkb:P90800	psi-mi:cng_caeel(display_long)|uniprotkb:Abnormal chemotaxis protein 4(gene name synonym)|uniprotkb:ZC84.2(orf name)|uniprotkb:tax-4(gene name)|psi-mi:tax-4(display_short)	psi-mi:cng_caeel(display_long)|uniprotkb:Abnormal chemotaxis protein 4(gene name synonym)|uniprotkb:ZC84.2(orf name)|uniprotkb:tax-4(gene name)|psi-mi:tax-4(display_short)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Zheng et al. (2020)	pubmed:32483338|imex:IM-28630	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26984735|emdb:EMD-21649|wwpdb:6WEj|imex:IM-28630-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-CEL-5620916|ensemblmetazoa:ZC84.2.1(transcript)|go:"GO:0003031"(detection of carbon dioxide)|go:"GO:0005222"(intracellular cAMP-activated cation channel activity)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007602"(phototransduction)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0009454"(aerotaxis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030553"(cGMP binding)|go:"GO:0034703"(cation channel complex)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040040"(thermosensory behavior)|ensemblmetazoa:WBGene00006526(gene)|go:"GO:0043052"(thermotaxis)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050907"(detection of chemical stimulus involved in sensory perception)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070482"(response to oxygen levels)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042048"(olfactory behavior)|refseq:NP_499033.1|rcsb pdb:5H3O|wormbase:ZC84.2|reactome:R-CEL-2485179|reactome:R-CEL-2514859|interpro:IPR032406|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR014710(RmlC-like jelly roll fold)|rcsb pdb:6WEJ|rcsb pdb:6WEK|rcsb pdb:6WEL|wwpdb:6WEJ(identity)|emdb:EMD-21649(identity)	reactome:R-CEL-5620916|ensemblmetazoa:ZC84.2.1(transcript)|go:"GO:0003031"(detection of carbon dioxide)|go:"GO:0005222"(intracellular cAMP-activated cation channel activity)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0006935"(chemotaxis)|go:"GO:0007199"(G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger)|go:"GO:0007602"(phototransduction)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0009454"(aerotaxis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030553"(cGMP binding)|go:"GO:0034703"(cation channel complex)|go:"GO:0040010"(positive regulation of growth rate)|go:"GO:0040040"(thermosensory behavior)|ensemblmetazoa:WBGene00006526(gene)|go:"GO:0043052"(thermotaxis)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050907"(detection of chemical stimulus involved in sensory perception)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070482"(response to oxygen levels)|go:"GO:0097543"(ciliary inversin compartment)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042048"(olfactory behavior)|refseq:NP_499033.1|rcsb pdb:5H3O|wormbase:ZC84.2|reactome:R-CEL-2485179|reactome:R-CEL-2514859|interpro:IPR032406|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR014710(RmlC-like jelly roll fold)|rcsb pdb:6WEJ|rcsb pdb:6WEK|rcsb pdb:6WEL|wwpdb:6WEJ(identity)|emdb:EMD-21649(identity)	-	-	-	figure legend:Fig. 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/12/20	2021/06/03	rogid:TkME5sarClA6pPM/JDFGXInjJ+I6239	rogid:TkME5sarClA6pPM/JDFGXInjJ+I6239	rigid:yRTGT5InNjTmhajr81MvO1PG1rE	false	-	-	4	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)