#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5UCC4 uniprotkb:Q8N766 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name) psi-mi:"MI:0020"(transmission electron microscopy) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619885|imex:IM-28019-1|wwpdb:6WW7|emdb:EMD-21929 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1 - - - figure legend:Fig. 1, figs. S2 and S3, and table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/06/02 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606 rigid:RWMau8e4owkJ9Nl+t44dqySLfYM false - - - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5UCC4 uniprotkb:Q15006 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619885|imex:IM-28019-1|wwpdb:6WW7|emdb:EMD-21929 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP - - - figure legend:Fig. 1, figs. S2 and S3, and table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/06/02 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rigid:RWMau8e4owkJ9Nl+t44dqySLfYM false - green fluorescent protein tag:?-? - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5UCC4 uniprotkb:Q9P0I2 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619885|imex:IM-28019-1|wwpdb:6WW7|emdb:EMD-21929 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692 - - - figure legend:Fig. 1, figs. S2 and S3, and table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/06/02 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606 rigid:RWMau8e4owkJ9Nl+t44dqySLfYM false - - - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5UCC4 uniprotkb:Q5J8M3 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name) psi-mi:"MI:0020"(transmission electron microscopy) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619885|imex:IM-28019-1|wwpdb:6WW7|emdb:EMD-21929 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane) - - - figure legend:Fig. 1, figs. S2 and S3, and table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/06/02 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606 rigid:RWMau8e4owkJ9Nl+t44dqySLfYM false - - - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5UCC4 uniprotkb:Q8N4V1 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619885|imex:IM-28019-1|wwpdb:6WW7|emdb:EMD-21929 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1 - - - figure legend:Fig. 1, figs. S2 and S3, and table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/06/02 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606 rigid:RWMau8e4owkJ9Nl+t44dqySLfYM false - - - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5UCC4 uniprotkb:Q9BV81 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619885|imex:IM-28019-1|wwpdb:6WW7|emdb:EMD-21929 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex) - - - figure legend:Fig. 1, figs. S2 and S3, and table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/06/02 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606 rigid:RWMau8e4owkJ9Nl+t44dqySLfYM false - - - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5UCC4 uniprotkb:Q9NPA0 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name) psi-mi:"MI:0020"(transmission electron microscopy) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619885|imex:IM-28019-1|wwpdb:6WW7|emdb:EMD-21929 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1 - - - figure legend:Fig. 1, figs. S2 and S3, and table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/06/02 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606 rigid:RWMau8e4owkJ9Nl+t44dqySLfYM false - - - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q5UCC4 uniprotkb:O43402 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym) psi-mi:"MI:0020"(transmission electron microscopy) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619885|imex:IM-28019-1|wwpdb:6WW7|emdb:EMD-21929 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1 - - - figure legend:Fig. 1, figs. S2 and S3, and table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/06/02 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606 rigid:RWMau8e4owkJ9Nl+t44dqySLfYM false - - - - psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q15006 uniprotkb:Q8N4V1 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1 - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:Q9Y3B6 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:Q9P0I2 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692 - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:Q9NPA0 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1 - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:O43402 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1 - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:Q5J8M3 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane) - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:Q5UCC4 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:Q8N766 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1 - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:Q9BV81 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25619968|imex:IM-28019-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex) - - - figure legend:"Supp Fig 1c (top panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q15006 uniprotkb:O43402 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620151|imex:IM-28019-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1 - - - figure legend:"Supp Fig 1c (bottom panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606 rigid:7bA1qGjmeKbzbOID/gYqfhjefMw false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15006 uniprotkb:Q9BV81 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620151|imex:IM-28019-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex) - - - figure legend:"Supp Fig 1c (bottom panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/05/26 2020/05/26 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606 rigid:7bA1qGjmeKbzbOID/gYqfhjefMw false green fluorescent protein tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5UCC4 uniprotkb:Q8N766 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1 - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5UCC4 uniprotkb:Q15006 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - green fluorescent protein tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5UCC4 uniprotkb:Q9P0I2 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692 - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5UCC4 uniprotkb:Q5J8M3 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane) - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5UCC4 uniprotkb:Q8N4V1 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1 - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5UCC4 uniprotkb:Q9BV81 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex) - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5UCC4 uniprotkb:Q9NPA0 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1 - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5UCC4 uniprotkb:O43402 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1 - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5UCC4 uniprotkb:Q9Y3B6 intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037 intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623 psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name) psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name) psi-mi:"MI:0071"(molecular sieving) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620189|imex:IM-28019-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W - - - figure legend:Supp Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/26 2020/05/26 rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606 rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606 rigid:sIlfff7CNfyFyIFsCaqNn22U/CE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8N4V1 uniprotkb:Q9BV81 intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7 intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322 psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym) psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25620365|imex:IM-28019-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1 refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex) - - - figure legend:Fig. S6c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9986(rabit-reticulocyte)|taxid:9986(Oryctolagus cuniculus reticulocyte) - 2020/05/26 2020/05/26 rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606 rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606 rigid:QZM8FDAnR4AI6RU21dGWITduC+8 false flag tag:?-?|35s radiolabel:?-? mutation with no effect:45-45,48-48|35s radiolabel:?-?|mutation with no effect:33-33,36-36 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q15006 uniprotkb:O43402 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25819144|imex:IM-28019-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1 - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9986(rabit-reticulocyte)|taxid:9986(Oryctolagus cuniculus reticulocyte) - 2020/05/26 2020/08/27 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606 rigid:xZ4isL0KC55t4x4X+VzpN/HhCwQ false 35s radiolabel:?-?|mutation disrupting interaction strength:200-200|mutation disrupting interaction strength:227-227|mutation with no effect:28-28|mutation with no effect:156-156|mutation with no effect:160-160|mutation with no effect:180-180|mutation with no effect:259-259|mutation with no effect:171-171 35s radiolabel:?-?|flag tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q15006 uniprotkb:Q9P0I2 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046 psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25819170|imex:IM-28019-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692 - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9986(rabit-reticulocyte)|taxid:9986(Oryctolagus cuniculus reticulocyte) - 2020/05/26 2020/08/27 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606 rigid:NK1qXjOhQ5Uc5VY1g7U9QARUsjI false 35s radiolabel:?-?|mutation with no effect:200-200|mutation disrupting interaction strength:227-227|mutation with no effect:28-28|mutation with no effect:156-156|mutation with no effect:160-160|mutation disrupting interaction strength:180-180|mutation disrupting interaction strength:259-259|mutation with no effect:171-171 35s radiolabel:?-?|flag tag:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8N4V1 uniprotkb:Q15006 intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7 intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853 psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym) psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Pleiner et al. (2020) imex:IM-28019|pubmed:32439656 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25819197|imex:IM-28019-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1 refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP - - - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9986(rabit-reticulocyte)|taxid:9986(Oryctolagus cuniculus reticulocyte) - 2020/05/26 2020/08/27 rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606 rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606 rigid:Cc5ukrC0xlp3lU+SIl1ZvM+h5j8 false 35s radiolabel:?-?|flag tag:?-? 35s radiolabel:?-?|mutation disrupting interaction strength:200-200|mutation disrupting interaction strength:227-227|mutation disrupting interaction strength:28-28|mutation disrupting interaction strength:156-156|mutation disrupting interaction strength:160-160|mutation with no effect:180-180|mutation with no effect:259-259|mutation with no effect:171-171 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)