#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75907 uniprotkb:O75907 intact:EBI-3906527|uniprotkb:D3DWL6|uniprotkb:B2RWQ2|uniprotkb:Q96BB8|ensembl:ENSP00000482264|ensembl:ENSP00000495489 intact:EBI-3906527|uniprotkb:D3DWL6|uniprotkb:B2RWQ2|uniprotkb:Q96BB8|ensembl:ENSP00000482264|ensembl:ENSP00000495489 psi-mi:dgat1_human(display_long)|uniprotkb:DGAT1(gene name)|psi-mi:DGAT1(display_short)|uniprotkb:AGRP1(gene name synonym)|uniprotkb:DGAT(gene name synonym)|uniprotkb:ACAT-related gene product 1(gene name synonym)|uniprotkb:Diglyceride acyltransferase(gene name synonym)|uniprotkb:Acyl-CoA retinol O-fatty-acyltransferase(gene name synonym) psi-mi:dgat1_human(display_long)|uniprotkb:DGAT1(gene name)|psi-mi:DGAT1(display_short)|uniprotkb:AGRP1(gene name synonym)|uniprotkb:DGAT(gene name synonym)|uniprotkb:ACAT-related gene product 1(gene name synonym)|uniprotkb:Diglyceride acyltransferase(gene name synonym)|uniprotkb:Acyl-CoA retinol O-fatty-acyltransferase(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Xuewu et al. (2020) pubmed:32433611|imex:IM-28228 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-25634236|imex:IM-28228-1|wwpdb:6VYI|emdb:EMD-21461|wwpdb:6VZ1|emdb:EMDB-21481|emdb:EMDB-21488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036211.2|ensembl:ENSG00000185000(gene)|ensembl:ENSG00000285482(gene)|ensembl:ENST00000528718(transcript)|ensembl:ENST00000644790(transcript)|go:"GO:0003846"(2-acylglycerol O-acyltransferase activity)|go:"GO:0004144"(diacylglycerol O-acyltransferase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0019915"(lipid storage)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0050252"(retinol O-fatty-acyltransferase activity)|go:"GO:0055089"(fatty acid homeostasis)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR027251|mint:O75907|rcsb pdb:6VP0|rcsb pdb:6VYI|rcsb pdb:6VZ1|reactome:R-HSA-1482883|reactome:R-HSA-6798695|reactome:R-HSA-75109 refseq:NP_036211.2|ensembl:ENSG00000185000(gene)|ensembl:ENSG00000285482(gene)|ensembl:ENST00000528718(transcript)|ensembl:ENST00000644790(transcript)|go:"GO:0003846"(2-acylglycerol O-acyltransferase activity)|go:"GO:0004144"(diacylglycerol O-acyltransferase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006640"(monoacylglycerol biosynthetic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0019915"(lipid storage)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0050252"(retinol O-fatty-acyltransferase activity)|go:"GO:0055089"(fatty acid homeostasis)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR027251|mint:O75907|rcsb pdb:6VP0|rcsb pdb:6VYI|rcsb pdb:6VZ1|reactome:R-HSA-1482883|reactome:R-HSA-6798695|reactome:R-HSA-75109 - - - figure legend:Fig 1, Extended Data Table 1, Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/29 2020/05/29 rogid:21iLqDiwzbSaVWIXFPlV5GjbRgY9606 rogid:21iLqDiwzbSaVWIXFPlV5GjbRgY9606 rigid:izj7OFRW2AuAuPH8QeMP2hZ+ank false - - 2 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)