#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00452	uniprotkb:P69924	intact:EBI-370018|uniprotkb:P78177|uniprotkb:P78088|ensemblbacteria:AAC75294|ensemblbacteria:BAA16053	intact:EBI-555196|uniprotkb:P00453|ensemblbacteria:AAC75295|ensemblbacteria:BAA16054	psi-mi:rir1_ecoli(display_long)|uniprotkb:nrdA(gene name)|psi-mi:nrdA(display_short)|uniprotkb:dnaF(gene name synonym)|uniprotkb:Protein B1(gene name synonym)|uniprotkb:b2234(locus name)|uniprotkb:Ribonucleoside-diphosphate reductase 1 R1 subunit(gene name synonym)|uniprotkb:Ribonucleotide reductase 1(gene name synonym)|uniprotkb:JW2228(locus name)	psi-mi:rir2_ecoli(display_long)|uniprotkb:Ribonucleotide reductase 1(gene name synonym)|uniprotkb:Protein B2(gene name synonym)|uniprotkb:Protein R2(gene name synonym)|uniprotkb:nrdB(gene name)|psi-mi:nrdB(display_short)|uniprotkb:ftsB(gene name synonym)|uniprotkb:b2235(locus name)|uniprotkb:JW2229(locus name)	psi-mi:"MI:2339"(electron microscopy 3D single particle reconstruction)	Kang et al. (2020)	pubmed:32217749|imex:IM-28655	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-26572796|imex:IM-28655-1|wwpdb:6W4X|emdb:EMD-21540	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC75294(transcript)|ensemblbacteria:b2234(gene)|ensemblbacteria:BAA16053(gene)|ensemblbacteria:BAA16053(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1QFN|rcsb pdb:1R1R|rcsb pdb:1RLR|rcsb pdb:2R1R|rcsb pdb:2X0X|rcsb pdb:2XAK|rcsb pdb:2XAP|rcsb pdb:2XAV|rcsb pdb:2XAW|rcsb pdb:2XAX|rcsb pdb:2XAY|rcsb pdb:2XAZ|rcsb pdb:2XO4|rcsb pdb:2XO5|rcsb pdb:3R1R|rcsb pdb:3UUS|rcsb pdb:4ERM|rcsb pdb:4ERP|rcsb pdb:4R1R|rcsb pdb:5CNS|rcsb pdb:5CNT|rcsb pdb:5CNU|rcsb pdb:5CNV|rcsb pdb:5R1R|rcsb pdb:6R1R|rcsb pdb:6W4X|rcsb pdb:7R1R|refseq:WP_001075164.1|refseq:NP_416737.1|dip:DIP-584N	refseq:NP_416738.1|refseq:WP_000332037.1|dip:DIP-36213N|ensemblbacteria:AAC75295(transcript)|ensemblbacteria:b2235(gene)|ensemblbacteria:BAA16054(gene)|ensemblbacteria:BAA16054(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0042802"(identical protein binding)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1AV8|rcsb pdb:1BIQ|rcsb pdb:1JPR|rcsb pdb:1JQC|rcsb pdb:1MRR|rcsb pdb:1MXR|rcsb pdb:1PFR|rcsb pdb:1PIM|rcsb pdb:1PIU|rcsb pdb:1PIY|rcsb pdb:1PIZ|rcsb pdb:1PJ0|rcsb pdb:1PJ1|rcsb pdb:1PM2|rcsb pdb:1R1R|rcsb pdb:1R65|rcsb pdb:1RIB|rcsb pdb:1RNR|rcsb pdb:1RSR|rcsb pdb:1RSV|rcsb pdb:1XIK|rcsb pdb:1YFD|rcsb pdb:2ALX|rcsb pdb:2AV8|rcsb pdb:2R1R|rcsb pdb:2X0X|rcsb pdb:2XAK|rcsb pdb:2XAP|rcsb pdb:2XAV|rcsb pdb:2XAW|rcsb pdb:2XAX|rcsb pdb:2XAY|rcsb pdb:2XAZ|rcsb pdb:2XO4|rcsb pdb:2XO5|rcsb pdb:2XOF|rcsb pdb:3R1R|rcsb pdb:3UUS|rcsb pdb:4ERM|rcsb pdb:4ERP|rcsb pdb:4R1R|rcsb pdb:5CI2|rcsb pdb:5CI3|rcsb pdb:5CNS|rcsb pdb:5CNT|rcsb pdb:5CNU|rcsb pdb:5CNV|rcsb pdb:5R1R|rcsb pdb:6R1R|rcsb pdb:6W4X|rcsb pdb:7R1R	-	-	-	figure legend:Figure 1, Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/20	2020/12/31	rogid:XdJE47xPcAa/C7+LU76gQcIMrL083333	rogid:42pZa9Gzjeb/xN8QIpmolT+yu0M83333	rigid:xhs3cusljmEtIUyQmpoYlCn/MbM	false	-	mutation:53-53|halogenated tyrosine:123-123	2	2	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)