#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75427 uniprotkb:Q8NF50 intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689 intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|ensembl:ENSP00000394888|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|intact:EBI-11070681 psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym) psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:"MI:0663"(confocal microscopy) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25400519|imex:IM-26436-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002310.2|refseq:NP_001276863.1|ensembl:ENSG00000077454(gene)|ensembl:ENST00000310300(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0016605"(PML body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 refseq:XP_011516347.1|refseq:XP_011516349.1|ensembl:ENSG00000107099(gene)|ensembl:ENST00000432829(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061485"(memory T cell proliferation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:XP_011516350.1|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_016870662.1 go:"GO:0005783"(endoplasmic reticulum) - - figure legend:Extended Data Fig. 8D|comment:Live confocal micrographs of MDCK cells coexpressing CFP-DOCK8 and the indicated LRCH proteins and fragments thereof, showing the recruitment of DOCK8 to the ER by LRCH1 and LRCH4, or to the cell periphery by LRCH4-deltaTMR.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2020/01/15 2020/01/20 rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606 rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606 rigid:1i3mB+m1SZ0pTQNbR31lmf5tSIM false fluorescent protein tag:n-n cyan fluorescent protein tag:n-n - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q3KR16-1 uniprotkb:P04844 intact:EBI-25408239 intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) refseq:NP_001129243.1|refseq:NP_002942.2|ensembl:ENSG00000118705(gene)|ensembl:ENST00000237530(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007568"(aging)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042493"|go:"GO:0043022"(ribosome binding)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001311234.1|refseq:NP_001311235.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:P35658 intact:EBI-25408239 intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:Q8TAQ2 intact:EBI-25408239 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:O43251 intact:EBI-25408239 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:O14818 intact:EBI-25408239 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:Q6P1L8 intact:EBI-25408239 intact:EBI-1043903|ensembl:ENSP00000361084|uniprotkb:Q96Q72|uniprotkb:B2R575 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:rm14_human(display_long)|uniprotkb:MRPL14(gene name)|psi-mi:MRPL14(display_short)|uniprotkb:RPML32(gene name synonym)|uniprotkb:MRPL32(gene name synonym)|uniprotkb:39S ribosomal protein L32, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein uL14m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) ensembl:ENSG00000180992(gene)|ensembl:ENST00000372014(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR036853|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_115487.2|refseq:NP_001305696.1|refseq:NP_001305697.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:Iwh7qhYEwAsJk6e9hA2IiCcvey09606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:Q14533 intact:EBI-25408239 intact:EBI-739648|uniprotkb:Q14846|uniprotkb:Q16274|uniprotkb:Q8WU52|uniprotkb:Q9BR74|uniprotkb:Q17R48|ensembl:ENSP00000369349 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:krt81_human(display_long)|uniprotkb:Type II hair keratin Hb1(gene name synonym)|uniprotkb:ghHKb1(gene name synonym)|uniprotkb:Keratin-81(gene name synonym)|uniprotkb:Type-II keratin Kb21(gene name synonym)|uniprotkb:Hair keratin K2.9(gene name synonym)|uniprotkb:KRT81(gene name)|psi-mi:KRT81(display_short)|uniprotkb:KRTHB1(gene name synonym)|uniprotkb:MLN137(gene name synonym)|uniprotkb:Keratin, hair, basic, 1(gene name synonym)|uniprotkb:Metastatic lymph node 137 gene protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) refseq:NP_002272.2|ensembl:ENST00000327741(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|ensembl:ENSG00000205426(gene)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:Y/1YhLCN54gK8DZQyc4OqfNDwAs9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:P12268 intact:EBI-25408239 intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:Q13439 intact:EBI-25408239 intact:EBI-1037845|uniprotkb:Q13270|uniprotkb:Q13654|uniprotkb:Q14436|uniprotkb:F8W8Q7|uniprotkb:Q59EW8|ensembl:ENSP00000354486 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:goga4_human(display_long)|uniprotkb:GOLGA4(gene name)|psi-mi:GOLGA4(display_short)|uniprotkb:Trans-Golgi p230(gene name synonym)|uniprotkb:256 kDa golgin(gene name synonym)|uniprotkb:Golgin-245(gene name synonym)|uniprotkb:Protein 72.1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) refseq:NP_001166184.1|refseq:NP_002069.2|ensembl:ENSG00000144674(gene)|ensembl:ENST00000361924(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000237(GRIP)|rcsb pdb:1R4A|rcsb pdb:1UPT|reactome:R-HSA-6811440|reactome:R-HSA-9673768 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:iRvTCfQleDllP1zq0dlAVyX58JU9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:O14908 intact:EBI-25408239 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:Q96AE4 intact:EBI-25408239 intact:EBI-711404|uniprotkb:Q12828|ensembl:ENSP00000359804 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:fubp1_human(display_long)|uniprotkb:FUBP1(gene name)|psi-mi:FUBP1(display_short)|uniprotkb:DNA helicase V(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q96AE4|rcsb pdb:1J4W|rcsb pdb:2KXH|rcsb pdb:4LIJ|rcsb pdb:6Y24|rcsb pdb:6Y2C|rcsb pdb:6Y2D|ensembl:ENSG00000162613(gene)|ensembl:ENST00000370768(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|refseq:NP_003893.2|refseq:NP_001290362.1|refseq:XP_016858232.1|dip:DIP-47273N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:38IaQgYv8qLMAryXO0lbfzgjjsM9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KR16-1 uniprotkb:P53396 intact:EBI-25408239 intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259 psi-mi:q3kr161(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short) psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408244|imex:IM-26436-274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q3KR16-1(isoform-parent) refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606 rigid:1KWecsBvPOD/+6rC5nzbsmo/YX4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:Q9BUZ4 intact:EBI-25408274 intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:P62306 intact:EBI-25408274 intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:O15027 intact:EBI-25408274 intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:Q8N1F7 intact:EBI-25408274 intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:pkk5pooUC4yQShpqjiwNLddfy149606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:P39687 intact:EBI-25408274 intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:O15212 intact:EBI-25408274 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - crc64:8F138EAAE512A312 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:O60925 intact:EBI-25408274 intact:EBI-356919|uniprotkb:Q53F95|uniprotkb:Q96EX6|uniprotkb:B2RD02|ensembl:ENSP00000261813 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:pfd1_human(display_long)|uniprotkb:PFDN1(gene name)|psi-mi:PFDN1(display_short)|uniprotkb:PFD1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_002613.2|ensembl:ENSG00000113068(gene)|ensembl:ENST00000261813(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O60925|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:repqo0hQgD7XgRAZll8ucK2jwz49606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:Q9H583 intact:EBI-25408274 intact:EBI-1048716|uniprotkb:Q5T3Q8|uniprotkb:Q6P197|uniprotkb:Q9NW23|ensembl:ENSP00000355541 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:heat1_human(display_long)|uniprotkb:Protein BAP28(gene name synonym)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)|uniprotkb:BAP28(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 10 homolog(gene name synonym)|uniprotkb:UTP10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_060542.4|ensembl:ENSG00000119285(gene)|ensembl:ENST00000366582(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022125|interpro:IPR040191|mint:Q9H583|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:0WoP84UUVfXWppmvCYa/n5GTzc89606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:Q96AE4 intact:EBI-25408274 intact:EBI-711404|uniprotkb:Q12828|ensembl:ENSP00000359804 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:fubp1_human(display_long)|uniprotkb:FUBP1(gene name)|psi-mi:FUBP1(display_short)|uniprotkb:DNA helicase V(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q96AE4|rcsb pdb:1J4W|rcsb pdb:2KXH|rcsb pdb:4LIJ|rcsb pdb:6Y24|rcsb pdb:6Y2C|rcsb pdb:6Y2D|ensembl:ENSG00000162613(gene)|ensembl:ENST00000370768(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|refseq:NP_003893.2|refseq:NP_001290362.1|refseq:XP_016858232.1|dip:DIP-47273N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:38IaQgYv8qLMAryXO0lbfzgjjsM9606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:Q16531 intact:EBI-25408274 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:P01040 intact:EBI-25408274 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:O75534 intact:EBI-25408274 intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|ensembl:ENSP00000351329|ensembl:ENSP00000432958|uniprotkb:A8K281|uniprotkb:G5E9Q2 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307(gene)|ensembl:ENST00000358528(transcript)|ensembl:ENST00000534699(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008584"(male gonad development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|interpro:IPR012340(Nucleic acid-binding, OB-fold) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N4T4-1 uniprotkb:P11274 intact:EBI-25408274 intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3 psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408280|imex:IM-26436-234 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N4T4-1(isoform-parent) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rigid:CN0xH3i4tXZ/STG6+8EPQbzWEDE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:Q6NZI2 intact:EBI-25408312 intact:EBI-2559016|uniprotkb:O00535|uniprotkb:Q96H74|uniprotkb:Q6GMY1|uniprotkb:B2RAW7|uniprotkb:Q9BT85|uniprotkb:Q9HAP4|ensembl:ENSP00000349541 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:cavn1_human(display_long)|uniprotkb:CAVIN1(gene name)|psi-mi:CAVIN1(display_short)|uniprotkb:Cavin-1(gene name synonym)|uniprotkb:PTRF(gene name synonym)|uniprotkb:Polymerase I and transcript release factor(gene name synonym)|uniprotkb:FKSG13(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_036364.2|ensembl:ENSG00000177469(gene)|ensembl:ENST00000357037(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009306"(protein secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR026752|mint:Q6NZI2|reactome:R-HSA-73863|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|interpro:IPR033297|dip:DIP-48550N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:55dzpwSSfj8aEzmgHKYdrHfgYBg9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:Q96QC0 intact:EBI-25408312 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:Q99569 intact:EBI-25408312 intact:EBI-726447|uniprotkb:Q86W91|ensembl:ENSP00000374409 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:pkp4_human(display_long)|uniprotkb:p0071(gene name synonym)|uniprotkb:PKP4(gene name)|psi-mi:PKP4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_001005476.1|refseq:NP_003619.2|refseq:NP_001291898.1|refseq:NP_001291899.1|refseq:XP_011510318.1|ensembl:ENST00000389757|ensembl:ENSP00000374407|ensembl:ENSP00000374409|ensembl:ENSG00000144283(gene)|ensembl:ENST00000389759(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001533"(cornified envelope)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0072686"(mitotic spindle)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028443|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:Ii0+JmsNuDEPLxwiTJ8utGeaq4Q9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:P13667 intact:EBI-25408312 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:Q9NZL9 intact:EBI-25408312 intact:EBI-10317491|uniprotkb:B2R5Y6|uniprotkb:Q6NYC7|uniprotkb:Q27J92|uniprotkb:Q9BS89|uniprotkb:Q9H3E1|uniprotkb:Q3LIE8|uniprotkb:Q9UJ54|uniprotkb:Q1WAI7|uniprotkb:Q567T7|ensembl:ENSP00000325425 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:mat2b_human(display_long)|uniprotkb:MAT2B(gene name)|psi-mi:MAT2B(display_short)|uniprotkb:Methionine adenosyltransferase II beta(gene name synonym)|uniprotkb:Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase(gene name synonym)|uniprotkb:TGR(gene name synonym)|uniprotkb:MSTP045(orf name)|uniprotkb:Nbla02999(orf name)|uniprotkb:UNQ2435/PRO4995(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_037415.1|refseq:NP_877725.1|ensembl:ENSG00000038274(gene)|ensembl:ENST00000321757(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0048270"(methionine adenosyltransferase regulator activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005913(dTDP-4-dehydrorhamnose reductase)|interpro:IPR029903|interpro:IPR036291|rcsb pdb:2YDX|rcsb pdb:2YDY|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|reactome:R-HSA-156581|reactome:R-HSA-5689880 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:RxXcRktcrFe+9xm7qgSyZoci4rU9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:Q9UPP5 intact:EBI-25408312 intact:EBI-726932|uniprotkb:O14767|uniprotkb:Q8N3X7|uniprotkb:A0A1B0GWG1 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:k1107_human(display_long)|uniprotkb:KIAA1107(gene name)|psi-mi:KIAA1107(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_056052.3|interpro:IPR027907|go:"GO:0008021"(synaptic vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0044297"(cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0098793"(presynapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|interpro:IPR040121 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:QkmjeXmoPN2AN3Y3aVJNDyrOmAw9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:Q9H6K5 intact:EBI-25408312 intact:EBI-20810872|ensembl:ENSP00000482374|uniprotkb:A0A087WZ52|uniprotkb:Q9H3X1 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:prr36_human(display_long)|uniprotkb:PRR36(gene name)|psi-mi:PRR36(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) ensembl:ENSG00000183248(gene)|ensembl:ENST00000618550(transcript)|interpro:IPR027907|refseq:NP_001177396.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:icvXKI3FyBvYGy91MdGTscwhqmw9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:O60716 intact:EBI-25408312 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:P35222 intact:EBI-25408312 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:P35221 intact:EBI-25408312 intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:Q00536 intact:EBI-25408312 intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:P07355 intact:EBI-25408312 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T5U3-1 uniprotkb:Q09666 intact:EBI-25408312 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 psi-mi:q5t5u31(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym) psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408320|imex:IM-26436-276 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5T5U3-1(isoform-parent) refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 rigid:EFn627L34J3tr8cO2xCxNxArMLE false tag:n-n|sufficient binding region:14-1944 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P22314 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P60174 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P05455 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P30048 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P23284 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:Q9H307 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-681904|uniprotkb:Q9UQR9|uniprotkb:O60899|uniprotkb:Q53EM7|uniprotkb:Q6P5X4|uniprotkb:Q7KYL1|uniprotkb:Q99738|uniprotkb:Q9UHZ9|uniprotkb:B4DZX8|ensembl:ENSP00000216832 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:pinin_human(display_long)|uniprotkb:140 kDa nuclear and cell adhesion-related phosphoprotein(gene name synonym)|uniprotkb:Domain-rich serine protein(gene name synonym)|uniprotkb:Melanoma metastasis clone A protein(gene name synonym)|uniprotkb:Desmosome-associated protein(gene name synonym)|uniprotkb:SR-like protein(gene name synonym)|uniprotkb:Nuclear protein SDK3(gene name synonym)|uniprotkb:PNN(gene name)|psi-mi:PNN(display_short)|uniprotkb:DRS(gene name synonym)|uniprotkb:MEMA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_002678.2|dip:DIP-32950N|ensembl:ENSG00000100941(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|mint:Q9H307|ensembl:ENST00000216832(transcript) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:1pAhD0z8tks+HkWaYWkdMmSjk3s9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P07737 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P22392 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:Q13765 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-712216|ensembl:ENSP00000349212|ensembl:ENSP00000377469|ensembl:ENSP00000446801|ensembl:ENSP00000447821|ensembl:ENSP00000503345|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|uniprotkb:F8VU71 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) ensembl:ENSG00000196531(gene)|ensembl:ENST00000356769(transcript)|ensembl:ENST00000393891(transcript)|ensembl:ENST00000546392(transcript)|ensembl:ENST00000552540(transcript)|ensembl:ENST00000678066(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006412"(translation)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0015031"(protein transport)|go:"GO:0042060"(wound healing)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|go:"GO:0043403"(skeletal muscle tissue regeneration)|refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:Q86YT6 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-2129148|uniprotkb:Q2TB37|uniprotkb:Q68D01|uniprotkb:Q6YI51|uniprotkb:Q8NBY0|uniprotkb:Q8TCB5|uniprotkb:Q8TCL7|uniprotkb:Q9P2M3|uniprotkb:B0YJ38|ensembl:ENSP00000261537 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:mib1_human(display_long)|uniprotkb:MIB1(gene name)|psi-mi:MIB1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:KIAA1323(gene name synonym)|uniprotkb:ZZANK2(gene name synonym)|uniprotkb:Mind bomb homolog 1(gene name synonym)|uniprotkb:DAPK-interacting protein 1(gene name synonym)|uniprotkb:Zinc finger ZZ type with ankyrin repeat domain protein 2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_065825.1|ensembl:ENSG00000101752(gene)|ensembl:ENST00000261537(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001947"(heart looping)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR010606(Mib-herc2)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|interpro:IPR043145|mint:Q86YT6|rcsb pdb:4TSE|rcsb pdb:4XI6|rcsb pdb:4XI7|rcsb pdb:4XIB|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:+DhNmSTvuXexGhi2FyEuBv4pBiw9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P00338 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P61604 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:Q9C005 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P09622 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-353366|uniprotkb:Q14131|uniprotkb:Q14167|uniprotkb:Q59EV8|uniprotkb:Q8WTS4|uniprotkb:B2R5X0|ensembl:ENSP00000205402|ensembl:ENSP00000390667|uniprotkb:B4DHG0|uniprotkb:B4DT69 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:dldh_human(display_long)|uniprotkb:DLD(gene name)|psi-mi:DLD(display_short)|uniprotkb:GCSL(gene name synonym)|uniprotkb:LAD(gene name synonym)|uniprotkb:PHE3(gene name synonym)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Glycine cleavage system L protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_001276679.1|refseq:NP_000099.2|rcsb pdb:6I4Z|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043544"(lipoamide binding)|ensembl:ENSG00000091140(gene)|ensembl:ENST00000205402(transcript)|ensembl:ENST00000417551(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-6783984|reactome:R-HSA-70268|reactome:R-HSA-70895|reactome:R-HSA-71064|reactome:R-HSA-71403|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:P09622|rcsb pdb:1ZMC|rcsb pdb:1ZMD|rcsb pdb:1ZY8|rcsb pdb:2F5Z|rcsb pdb:3RNM|rcsb pdb:5J5Z|rcsb pdb:5NHG|rcsb pdb:6HG8|rcsb pdb:6I4P|rcsb pdb:6I4Q|rcsb pdb:6I4R|rcsb pdb:6I4S|rcsb pdb:6I4T|rcsb pdb:6I4U|refseq:NP_001276680.1|refseq:NP_001276681.1|dip:DIP-29027N - - caution:This sequence has been withdrawn from Uniprot.|crc64:7613492C516F3835 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:7Yf9KyBWf18686aOXVUwab65rl89606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P35659 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:Q16531 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P12277 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N264-1 uniprotkb:P24752 intact:EBI-15944596|ensembl:ENSP00000378611 intact:EBI-1051459|uniprotkb:B2R6H1|uniprotkb:G3XAB4|uniprotkb:Q96FG8|ensembl:ENSP00000265838 psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:thil_human(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:T2(gene name synonym)|uniprotkb:ACAT1(gene name)|psi-mi:ACAT1(display_short)|uniprotkb:ACAT(gene name synonym)|uniprotkb:MAT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408352|imex:IM-26436-236 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) refseq:NP_000010.1|ensembl:ENSG00000075239(gene)|ensembl:ENST00000265838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007420"(brain development)|go:"GO:0009725"(response to hormone)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016453"(C-acetyltransferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046356"(acetyl-CoA catabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072229"(metanephric proximal convoluted tubule development)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1902224"(ketone body metabolic process)|go:"GO:1902860"(propionyl-CoA biosynthetic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|rcsb pdb:2F2S|rcsb pdb:2IB7|rcsb pdb:2IB8|rcsb pdb:2IB9|rcsb pdb:2IBU|rcsb pdb:2IBW|rcsb pdb:2IBY|reactome:R-HSA-70895|reactome:R-HSA-77108|reactome:R-HSA-77111 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rogid:UYAY+kDdcJqx/hrDFoXH9rgtm/E9606 rigid:T6VWBeUZ5NLewDQI1+8B92Y9oR8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5V2 uniprotkb:Q8NFH5 intact:EBI-718372|uniprotkb:B9A045|uniprotkb:Q53QQ4|uniprotkb:Q53ST7|uniprotkb:Q6GMQ5|uniprotkb:Q9NQD6|uniprotkb:B4DMB8|uniprotkb:E9PC42|ensembl:ENSP00000264051 intact:EBI-9050429|uniprotkb:B4DP57|uniprotkb:B4DYB4|uniprotkb:Q4ZFZ9|uniprotkb:Q53S95|uniprotkb:Q8TDJ1|ensembl:ENSP00000295119 psi-mi:ngef_human(display_long)|uniprotkb:Eph-interacting exchange protein(gene name synonym)|uniprotkb:Neuronal guanine nucleotide exchange factor(gene name synonym)|uniprotkb:NGEF(gene name)|psi-mi:NGEF(display_short) psi-mi:nup35_human(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:NUP35(gene name)|psi-mi:NUP35(display_short)|uniprotkb:MP44(gene name synonym)|uniprotkb:NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Mitotic phosphoprotein 44(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408394|imex:IM-26436-238 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107562.1|refseq:NP_062824.2|refseq:XP_011509225.1|ensembl:ENSG00000066248(gene)|ensembl:ENST00000264051(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035635|interpro:IPR035899|interpro:IPR036028|mint:Q8N5V2|reactome:R-HSA-193648|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol) refseq:XP_006712317.1|refseq:XP_011508878.1|refseq:XP_011508879.1|refseq:NP_001274513.1|refseq:NP_612142.2|refseq:NP_001274514.1|dip:DIP-47308N|ensembl:ENSG00000163002(gene)|ensembl:ENST00000295119(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|mint:Q8NFH5|rcsb pdb:4LIR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oAu+8njDslYpqxQaq85zzC3hb209606 rogid:oFL2V05tM9dYT+fjUiqMLwxZYr89606 rigid:JqzzX5DoIf28qE8KXq7Tx9naftg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5V2 uniprotkb:P78344 intact:EBI-718372|uniprotkb:B9A045|uniprotkb:Q53QQ4|uniprotkb:Q53ST7|uniprotkb:Q6GMQ5|uniprotkb:Q9NQD6|uniprotkb:B4DMB8|uniprotkb:E9PC42|ensembl:ENSP00000264051 intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79 psi-mi:ngef_human(display_long)|uniprotkb:Eph-interacting exchange protein(gene name synonym)|uniprotkb:Neuronal guanine nucleotide exchange factor(gene name synonym)|uniprotkb:NGEF(gene name)|psi-mi:NGEF(display_short) psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408394|imex:IM-26436-238 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107562.1|refseq:NP_062824.2|refseq:XP_011509225.1|ensembl:ENSG00000066248(gene)|ensembl:ENST00000264051(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035635|interpro:IPR035899|interpro:IPR036028|mint:Q8N5V2|reactome:R-HSA-193648|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol) ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oAu+8njDslYpqxQaq85zzC3hb209606 rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606 rigid:JqzzX5DoIf28qE8KXq7Tx9naftg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5V2 uniprotkb:O15371 intact:EBI-718372|uniprotkb:B9A045|uniprotkb:Q53QQ4|uniprotkb:Q53ST7|uniprotkb:Q6GMQ5|uniprotkb:Q9NQD6|uniprotkb:B4DMB8|uniprotkb:E9PC42|ensembl:ENSP00000264051 intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1 psi-mi:ngef_human(display_long)|uniprotkb:Eph-interacting exchange protein(gene name synonym)|uniprotkb:Neuronal guanine nucleotide exchange factor(gene name synonym)|uniprotkb:NGEF(gene name)|psi-mi:NGEF(display_short) psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408394|imex:IM-26436-238 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107562.1|refseq:NP_062824.2|refseq:XP_011509225.1|ensembl:ENSG00000066248(gene)|ensembl:ENST00000264051(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035635|interpro:IPR035899|interpro:IPR036028|mint:Q8N5V2|reactome:R-HSA-193648|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol) refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oAu+8njDslYpqxQaq85zzC3hb209606 rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606 rigid:JqzzX5DoIf28qE8KXq7Tx9naftg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5V2 uniprotkb:O14579 intact:EBI-718372|uniprotkb:B9A045|uniprotkb:Q53QQ4|uniprotkb:Q53ST7|uniprotkb:Q6GMQ5|uniprotkb:Q9NQD6|uniprotkb:B4DMB8|uniprotkb:E9PC42|ensembl:ENSP00000264051 intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29 psi-mi:ngef_human(display_long)|uniprotkb:Eph-interacting exchange protein(gene name synonym)|uniprotkb:Neuronal guanine nucleotide exchange factor(gene name synonym)|uniprotkb:NGEF(gene name)|psi-mi:NGEF(display_short) psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408394|imex:IM-26436-238 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107562.1|refseq:NP_062824.2|refseq:XP_011509225.1|ensembl:ENSG00000066248(gene)|ensembl:ENST00000264051(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035635|interpro:IPR035899|interpro:IPR036028|mint:Q8N5V2|reactome:R-HSA-193648|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol) refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oAu+8njDslYpqxQaq85zzC3hb209606 rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606 rigid:JqzzX5DoIf28qE8KXq7Tx9naftg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5V2 uniprotkb:Q16740 intact:EBI-718372|uniprotkb:B9A045|uniprotkb:Q53QQ4|uniprotkb:Q53ST7|uniprotkb:Q6GMQ5|uniprotkb:Q9NQD6|uniprotkb:B4DMB8|uniprotkb:E9PC42|ensembl:ENSP00000264051 intact:EBI-1056029|uniprotkb:B2R4W5|ensembl:ENSP00000245816 psi-mi:ngef_human(display_long)|uniprotkb:Eph-interacting exchange protein(gene name synonym)|uniprotkb:Neuronal guanine nucleotide exchange factor(gene name synonym)|uniprotkb:NGEF(gene name)|psi-mi:NGEF(display_short) psi-mi:clpp_human(display_long)|uniprotkb:CLPP(gene name)|psi-mi:CLPP(display_short)|uniprotkb:Endopeptidase Clp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408394|imex:IM-26436-238 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001107562.1|refseq:NP_062824.2|refseq:XP_011509225.1|ensembl:ENSG00000066248(gene)|ensembl:ENST00000264051(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035635|interpro:IPR035899|interpro:IPR036028|mint:Q8N5V2|reactome:R-HSA-193648|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol) refseq:NP_006003.1|ensembl:ENSG00000125656(gene)|ensembl:ENST00000245816(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0008233"(peptidase activity)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|interpro:IPR023562|interpro:IPR029045|interpro:IPR033135|rcsb pdb:1TG6|rcsb pdb:6BBA|rcsb pdb:6DL7|rcsb pdb:6H23|dip:DIP-50384N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:oAu+8njDslYpqxQaq85zzC3hb209606 rogid:HTSz7OgKpaMKvoab6xXG0i4ZcBk9606 rigid:JqzzX5DoIf28qE8KXq7Tx9naftg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3L3-1 uniprotkb:Q9Y2W2 intact:EBI-25408410 intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8 psi-mi:q9y3l31(display_long)|uniprotkb:SH3BP1(gene name)|psi-mi:SH3BP1(display_short) psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408415|imex:IM-26436-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9Y3L3-1(isoform-parent) rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FLnCGJhsS+syrKyjVQG4Q6UcZeU9606 rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606 rigid:9OBM9FXFIFlbqtpQVK3vztAPqw0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3L3-1 uniprotkb:Q96B97 intact:EBI-25408410 intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921 psi-mi:q9y3l31(display_long)|uniprotkb:SH3BP1(gene name)|psi-mi:SH3BP1(display_short) psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408415|imex:IM-26436-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9Y3L3-1(isoform-parent) refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FLnCGJhsS+syrKyjVQG4Q6UcZeU9606 rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606 rigid:9OBM9FXFIFlbqtpQVK3vztAPqw0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3L3-1 uniprotkb:O00422 intact:EBI-25408410 intact:EBI-1044156|uniprotkb:Q2TTR4|uniprotkb:Q6IAW9|uniprotkb:Q8N606|uniprotkb:Q9UF14|ensembl:ENSP00000475925|uniprotkb:B2R494|uniprotkb:X6RAL5 psi-mi:q9y3l31(display_long)|uniprotkb:SH3BP1(gene name)|psi-mi:SH3BP1(display_short) psi-mi:sap18_human(display_long)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 38 protein(gene name synonym)|uniprotkb:2HOR0202(gene name synonym)|uniprotkb:SAP18(gene name)|psi-mi:SAP18(display_short)|uniprotkb:GIG38(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408415|imex:IM-26436-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9Y3L3-1(isoform-parent) ensembl:ENSG00000150459(gene)|ensembl:ENST00000607003(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O00422|rcsb pdb:2HDE|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|refseq:NP_005861.2|dip:DIP-33590N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FLnCGJhsS+syrKyjVQG4Q6UcZeU9606 rogid:eJoksFCc7vBoAjJEpnXJvc/yg+Q9606 rigid:9OBM9FXFIFlbqtpQVK3vztAPqw0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3L3-1 uniprotkb:Q8N567 intact:EBI-25408410 intact:EBI-5235536|uniprotkb:B2RAE7|uniprotkb:Q9H027|ensembl:ENSP00000254037|ensembl:ENSP00000369546|ensembl:ENSP00000385047|ensembl:ENSP00000412637 psi-mi:q9y3l31(display_long)|uniprotkb:SH3BP1(gene name)|psi-mi:SH3BP1(display_short) psi-mi:zchc9_human(display_long)|uniprotkb:ZCCHC9(gene name)|psi-mi:ZCCHC9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408415|imex:IM-26436-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9Y3L3-1(isoform-parent) refseq:NP_001124507.1|refseq:NP_001124508.1|refseq:NP_115656.1|ensembl:ENSG00000131732(gene)|ensembl:ENST00000254037(transcript)|ensembl:ENST00000380199(transcript)|ensembl:ENST00000407610(transcript)|ensembl:ENST00000438268(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR042246 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FLnCGJhsS+syrKyjVQG4Q6UcZeU9606 rogid:M/NIA60lFfPQAjGBMtHILP1zw/s9606 rigid:9OBM9FXFIFlbqtpQVK3vztAPqw0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3L3-1 uniprotkb:Q9UNF0 intact:EBI-25408410 intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000385040|ensembl:ENSP00000385372|ensembl:ENSP00000263246 psi-mi:q9y3l31(display_long)|uniprotkb:SH3BP1(gene name)|psi-mi:SH3BP1(display_short) psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408415|imex:IM-26436-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9Y3L3-1(isoform-parent) refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|refseq:XP_016884053.1|ensembl:ENST00000263246(transcript)|ensembl:ENST00000402229(transcript)|ensembl:ENST00000403744(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000100266(gene)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FLnCGJhsS+syrKyjVQG4Q6UcZeU9606 rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606 rigid:9OBM9FXFIFlbqtpQVK3vztAPqw0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3L3-1 uniprotkb:Q9Y3C1 intact:EBI-25408410 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:q9y3l31(display_long)|uniprotkb:SH3BP1(gene name)|psi-mi:SH3BP1(display_short) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408415|imex:IM-26436-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9Y3L3-1(isoform-parent) refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FLnCGJhsS+syrKyjVQG4Q6UcZeU9606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 rigid:9OBM9FXFIFlbqtpQVK3vztAPqw0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27986-1 uniprotkb:Q13185 intact:EBI-16747265|ensembl:ENSP00000428056|ensembl:ENSP00000429277 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:p27986-1(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408433|imex:IM-26436-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|intact:EBI-79464(isoform-parent)|uniprotkb:P27986-1(isoform-parent) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:SeJJg5f0VIeUchb+ss9Jo7WGsyA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27986-1 uniprotkb:Q9NNW5 intact:EBI-16747265|ensembl:ENSP00000428056|ensembl:ENSP00000429277 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:p27986-1(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408433|imex:IM-26436-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|intact:EBI-79464(isoform-parent)|uniprotkb:P27986-1(isoform-parent) refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 rigid:SeJJg5f0VIeUchb+ss9Jo7WGsyA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27986-1 uniprotkb:O00459 intact:EBI-16747265|ensembl:ENSP00000428056|ensembl:ENSP00000429277 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:p27986-1(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408433|imex:IM-26436-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|intact:EBI-79464(isoform-parent)|uniprotkb:P27986-1(isoform-parent) ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 rigid:SeJJg5f0VIeUchb+ss9Jo7WGsyA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27986-1 uniprotkb:Q9Y2I1 intact:EBI-16747265|ensembl:ENSP00000428056|ensembl:ENSP00000429277 intact:EBI-2688731|uniprotkb:Q6PIB4|uniprotkb:Q9UEU4|uniprotkb:Q7L8M3|uniprotkb:Q6PGP3|uniprotkb:Q9UFW3|uniprotkb:Q7Z2X6|uniprotkb:Q9UES6|uniprotkb:C9J245|ensembl:ENSP00000339958|ensembl:ENSP00000418232 psi-mi:p27986-1(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym) psi-mi:nisch_human(display_long)|uniprotkb:IRAS(gene name synonym)|uniprotkb:KIAA0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor antisera-selected protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym)|uniprotkb:Imidazoline-1 receptor candidate protein(gene name synonym)|uniprotkb:NISCH(gene name)|psi-mi:NISCH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408433|imex:IM-26436-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|intact:EBI-79464(isoform-parent)|uniprotkb:P27986-1(isoform-parent) refseq:NP_009115.2|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q9Y2I1|rcsb pdb:3P0C|reactome:R-HSA-9013149|reactome:R-HSA-9696264|reactome:R-HSA-9696270|ensembl:ENSG00000010322(gene)|ensembl:ENST00000345716(transcript)|ensembl:ENST00000479054(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|refseq:NP_001263222.1|refseq:NP_001263223.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 rogid:GuBgG6MUrD5p1hIhGGmrtCjT0jQ9606 rigid:SeJJg5f0VIeUchb+ss9Jo7WGsyA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27986-1 uniprotkb:Q9UET6 intact:EBI-16747265|ensembl:ENSP00000428056|ensembl:ENSP00000429277 intact:EBI-1055987|uniprotkb:O75670|uniprotkb:B2RCJ0|ensembl:ENSP00000326948 psi-mi:p27986-1(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym) psi-mi:trm7_human(display_long)|uniprotkb:FTSJ1(gene name)|psi-mi:FTSJ1(display_short)|uniprotkb:JM23(orf name)|uniprotkb:Protein ftsJ homolog 1(gene name synonym)|uniprotkb:2'-O-ribose RNA methyltransferase TRM7 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408433|imex:IM-26436-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|intact:EBI-79464(isoform-parent)|uniprotkb:P27986-1(isoform-parent) refseq:NP_036412.1|refseq:NP_803188.1|refseq:NP_001269086.1|refseq:XP_005272652.1|ensembl:ENST00000348411(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0002128"(tRNA nucleoside ribose methylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008175"(tRNA methyltransferase activity)|go:"GO:0009020"("tRNA (guanosine-2'-O-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0052666"("tRNA (cytosine-2'-O-)-methyltransferase activity")|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR028590|interpro:IPR029063|mint:Q9UET6|reactome:R-HSA-6782315|ensembl:ENSG00000068438(gene) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 rogid:N4L9nsU0Wj3FMVjYALdxpx56aZs9606 rigid:SeJJg5f0VIeUchb+ss9Jo7WGsyA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27986-1 uniprotkb:P46109 intact:EBI-16747265|ensembl:ENSP00000428056|ensembl:ENSP00000429277 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:p27986-1(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408433|imex:IM-26436-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|intact:EBI-79464(isoform-parent)|uniprotkb:P27986-1(isoform-parent) refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 rigid:SeJJg5f0VIeUchb+ss9Jo7WGsyA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07889-1 uniprotkb:Q8NBS9 intact:EBI-25408451 intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2 psi-mi:q078891(display_long)|uniprotkb:SOS1(gene name)|psi-mi:SOS1(display_short) psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408457|imex:IM-26436-74 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07889-1(isoform-parent) ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SPXIrLMDF+XVcqKxBFgWsRGCFw89606 rogid:bz5VVWMPFLTRKwph60UFASjsFN49606 rigid:pT9Ta/ZHHpCQ5A7qAQLuXrp97zI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07889-1 uniprotkb:Q15811 intact:EBI-25408451 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 psi-mi:q078891(display_long)|uniprotkb:SOS1(gene name)|psi-mi:SOS1(display_short) psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408457|imex:IM-26436-74 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07889-1(isoform-parent) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SPXIrLMDF+XVcqKxBFgWsRGCFw89606 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rigid:pT9Ta/ZHHpCQ5A7qAQLuXrp97zI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07889-1 uniprotkb:P62993 intact:EBI-25408451 intact:EBI-401755|ensembl:ENSP00000339007|uniprotkb:P29354|uniprotkb:Q14450|uniprotkb:Q63057|uniprotkb:Q63059|ensembl:ENSP00000376345|ensembl:ENSP00000376347|ensembl:ENSP00000496913 psi-mi:q078891(display_long)|uniprotkb:SOS1(gene name)|psi-mi:SOS1(display_short) psi-mi:grb2_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408457|imex:IM-26436-74 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07889-1(isoform-parent) ensembl:ENSG00000177885(gene)|refseq:NP_002077.1|refseq:NP_987102.1|ensembl:ENST00000316804(transcript)|ensembl:ENST00000392562(transcript)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|ensembl:ENST00000392564(transcript)|ensembl:ENST00000648046(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0012506"(vesicle membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|mint:P62993|rcsb pdb:1AZE|rcsb pdb:1BM2|rcsb pdb:1BMB|rcsb pdb:1CJ1|rcsb pdb:1FHS|rcsb pdb:1FYR|rcsb pdb:1GCQ|rcsb pdb:1GFC|rcsb pdb:1GFD|rcsb pdb:1GHU|rcsb pdb:1GRI|rcsb pdb:1IO6|rcsb pdb:1JYQ|rcsb pdb:1JYR|rcsb pdb:1JYU|rcsb pdb:1QG1|rcsb pdb:1TZE|rcsb pdb:1X0N|rcsb pdb:1ZFP|rcsb pdb:2AOA|rcsb pdb:2AOB|rcsb pdb:2H46|rcsb pdb:2H5K|rcsb pdb:2HUW|rcsb pdb:2VVK|rcsb pdb:2VWF|rcsb pdb:2W0Z|rcsb pdb:3C7I|rcsb pdb:3IMD|rcsb pdb:3IMJ|rcsb pdb:3IN7|rcsb pdb:3IN8|rcsb pdb:3KFJ|rcsb pdb:3MXC|rcsb pdb:3N7Y|rcsb pdb:3N84|rcsb pdb:3N8M|rcsb pdb:3OV1|rcsb pdb:3OVE|rcsb pdb:3MXY|rcsb pdb:3S8L|rcsb pdb:3S8N|rcsb pdb:3S8O|rcsb pdb:3WA4|rcsb pdb:4P9V|rcsb pdb:4P9Z|rcsb pdb:5CDW|rcsb pdb:6ICG|rcsb pdb:6ICH|rcsb pdb:6SDF|rcsb pdb:6VK2|rcsb pdb:6WM1|rcsb pdb:6WO2|reactome:R-HSA-109704|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2029482|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-388841|reactome:R-HSA-389359|reactome:R-HSA-391160|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8865999|reactome:R-HSA-8875360|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8983432|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028335|reactome:R-HSA-5654689|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9645135|reactome:R-HSA-9664422|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|dip:DIP-29229N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SPXIrLMDF+XVcqKxBFgWsRGCFw89606 rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606 rigid:pT9Ta/ZHHpCQ5A7qAQLuXrp97zI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07889-1 uniprotkb:P46109 intact:EBI-25408451 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:q078891(display_long)|uniprotkb:SOS1(gene name)|psi-mi:SOS1(display_short) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408457|imex:IM-26436-74 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07889-1(isoform-parent) refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SPXIrLMDF+XVcqKxBFgWsRGCFw89606 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 rigid:pT9Ta/ZHHpCQ5A7qAQLuXrp97zI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07889-1 uniprotkb:P46108 intact:EBI-25408451 intact:EBI-886|uniprotkb:B0LPE8|uniprotkb:Q96HJ0|uniprotkb:A8MWE8|uniprotkb:Q96GA9|uniprotkb:D3DTH6|intact:EBI-28974221|ensembl:ENSP00000300574|intact:EBI-16429791 psi-mi:q078891(display_long)|uniprotkb:SOS1(gene name)|psi-mi:SOS1(display_short) psi-mi:crk_human(display_long)|uniprotkb:Proto-oncogene c-Crk(gene name synonym)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)|uniprotkb:p38(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408457|imex:IM-26436-74 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07889-1(isoform-parent) ensembl:ENSP00000300574|ensembl:ENST00000398970|ensembl:ENSP00000381942|refseq:NP_005197.3|refseq:NP_058431.2|ensembl:ENSG00000167193(gene)|ensembl:ENST00000300574(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001878"(response to yeast)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|dip:DIP-199N|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46108|rcsb pdb:1JU5|rcsb pdb:2DVJ|rcsb pdb:2EYV|rcsb pdb:2EYW|rcsb pdb:2EYX|rcsb pdb:2EYY|rcsb pdb:2EYZ|rcsb pdb:2MS4|rcsb pdb:5UL6|rcsb pdb:6ATV|reactome:R-HSA-170984|reactome:R-HSA-186763|reactome:R-HSA-2029482|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-912631|reactome:R-HSA-9664422 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SPXIrLMDF+XVcqKxBFgWsRGCFw89606 rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606 rigid:pT9Ta/ZHHpCQ5A7qAQLuXrp97zI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07889-1 uniprotkb:O00499 intact:EBI-25408451 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:q078891(display_long)|uniprotkb:SOS1(gene name)|psi-mi:SOS1(display_short) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408457|imex:IM-26436-74 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07889-1(isoform-parent) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SPXIrLMDF+XVcqKxBFgWsRGCFw89606 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 rigid:pT9Ta/ZHHpCQ5A7qAQLuXrp97zI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y4F1 uniprotkb:P82673 intact:EBI-5235630|uniprotkb:Q6IQ29|uniprotkb:Q5JVI9|ensembl:ENSP00000322926 intact:EBI-2513649|ensembl:ENSP00000081029|uniprotkb:Q6P4C6|uniprotkb:Q7L1M6|uniprotkb:Q9HC14|uniprotkb:Q96AI0|uniprotkb:Q32LZ1|uniprotkb:Q9H044|uniprotkb:Q9P1R5|uniprotkb:Q8NBP4 psi-mi:farp1_human(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym) psi-mi:rt35_human(display_long)|uniprotkb:MRPS35(gene name)|psi-mi:MRPS35(display_short)|uniprotkb:MRPS28(gene name synonym)|uniprotkb:28S ribosomal protein S28, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS35(gene name synonym)|uniprotkb:HDCMD11P(orf name)|uniprotkb:MDS023(orf name)|uniprotkb:PSEC0213(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408475|imex:IM-26436-114 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005757.1|refseq:NP_001273768.1|refseq:NP_001001715.2|refseq:XP_016875801.1|ensembl:ENSG00000152767(gene)|ensembl:ENST00000319562(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|mint:Q9Y4F1|rcsb pdb:4H6Y|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034 ensembl:ENSG00000061794(gene)|ensembl:ENST00000081029(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR019349|interpro:IPR039848|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001177793.1|refseq:NP_068593.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EFAIqKR/G9qOxNYCZqkJDSqU+TU9606 rogid:L7fhBRRkth1ePVbRtuVTvC5zcR09606 rigid:/RtC1rGbPkUSZ8P25TuE80z6RIo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y4F1 uniprotkb:O94903 intact:EBI-5235630|uniprotkb:Q6IQ29|uniprotkb:Q5JVI9|ensembl:ENSP00000322926 intact:EBI-2860631|uniprotkb:Q6FI94|ensembl:ENSP00000333551 psi-mi:farp1_human(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym) psi-mi:plphp_human(display_long)|uniprotkb:PLPBP(gene name)|psi-mi:PLPBP(display_short)|uniprotkb:PROSC(gene name synonym)|uniprotkb:Proline synthase co-transcribed bacterial homolog protein(gene name synonym)|uniprotkb:Pyridoxal phosphate-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408475|imex:IM-26436-114 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005757.1|refseq:NP_001273768.1|refseq:NP_001001715.2|refseq:XP_016875801.1|ensembl:ENSG00000152767(gene)|ensembl:ENST00000319562(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|mint:Q9Y4F1|rcsb pdb:4H6Y|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034 refseq:NP_009129.1|ensembl:ENSG00000147471(gene)|ensembl:ENST00000328195(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR011078(Predicted pyridoxal phosphate-dependent enzyme, YBL036C type)|interpro:IPR029066|mint:O94903 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EFAIqKR/G9qOxNYCZqkJDSqU+TU9606 rogid:xrOEPMjG0y+otG21Al6Q0UuQcEY9606 rigid:/RtC1rGbPkUSZ8P25TuE80z6RIo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y4F1 uniprotkb:P35658 intact:EBI-5235630|uniprotkb:Q6IQ29|uniprotkb:Q5JVI9|ensembl:ENSP00000322926 intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400 psi-mi:farp1_human(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym) psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408475|imex:IM-26436-114 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005757.1|refseq:NP_001273768.1|refseq:NP_001001715.2|refseq:XP_016875801.1|ensembl:ENSG00000152767(gene)|ensembl:ENST00000319562(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|mint:Q9Y4F1|rcsb pdb:4H6Y|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034 ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EFAIqKR/G9qOxNYCZqkJDSqU+TU9606 rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606 rigid:/RtC1rGbPkUSZ8P25TuE80z6RIo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y4F1 uniprotkb:Q9Y3T9 intact:EBI-5235630|uniprotkb:Q6IQ29|uniprotkb:Q5JVI9|ensembl:ENSP00000322926 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:farp1_human(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408475|imex:IM-26436-114 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005757.1|refseq:NP_001273768.1|refseq:NP_001001715.2|refseq:XP_016875801.1|ensembl:ENSG00000152767(gene)|ensembl:ENST00000319562(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|mint:Q9Y4F1|rcsb pdb:4H6Y|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034 refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EFAIqKR/G9qOxNYCZqkJDSqU+TU9606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 rigid:/RtC1rGbPkUSZ8P25TuE80z6RIo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y4F1 uniprotkb:Q5SW79 intact:EBI-5235630|uniprotkb:Q6IQ29|uniprotkb:Q5JVI9|ensembl:ENSP00000322926 intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344 psi-mi:farp1_human(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym) psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408475|imex:IM-26436-114 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005757.1|refseq:NP_001273768.1|refseq:NP_001001715.2|refseq:XP_016875801.1|ensembl:ENSG00000152767(gene)|ensembl:ENST00000319562(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|mint:Q9Y4F1|rcsb pdb:4H6Y|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034 refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EFAIqKR/G9qOxNYCZqkJDSqU+TU9606 rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606 rigid:/RtC1rGbPkUSZ8P25TuE80z6RIo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y4F1 uniprotkb:Q16543 intact:EBI-5235630|uniprotkb:Q6IQ29|uniprotkb:Q5JVI9|ensembl:ENSP00000322926 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:farp1_human(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408475|imex:IM-26436-114 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005757.1|refseq:NP_001273768.1|refseq:NP_001001715.2|refseq:XP_016875801.1|ensembl:ENSG00000152767(gene)|ensembl:ENST00000319562(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|mint:Q9Y4F1|rcsb pdb:4H6Y|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034 refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EFAIqKR/G9qOxNYCZqkJDSqU+TU9606 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 rigid:/RtC1rGbPkUSZ8P25TuE80z6RIo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P42331-3 uniprotkb:Q8N726 intact:EBI-25408493 intact:EBI-625922|uniprotkb:Q13195|uniprotkb:Q13399|uniprotkb:Q16360|uniprotkb:Q7KZR9|ensembl:ENSP00000432664|ensembl:ENSP00000462950|uniprotkb:D3DRK2 psi-mi:p423313(display_long)|uniprotkb:ARHGAP25(gene name)|psi-mi:ARHGAP25(display_short)|uniprotkb:KIAA0053(gene name synonym) psi-mi:arf_human(display_long)|uniprotkb:p14ARF(gene name synonym)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:MLM(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408499|imex:IM-26436-278 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P42331-3(isoform-parent) ensembl:ENSG00000147889(gene)|ensembl:ENST00000530628(transcript)|ensembl:ENST00000579755(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0050821"(protein stabilization)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090398"(cellular senescence)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|mint:Q8N726|reactome:R-HSA-111471|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-6804757|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9645722|reactome:R-HSA-9646303|reactome:R-HSA-9646304|refseq:NP_478102.2|dip:DIP-24171N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:t2rOqCe4heCaixiChlpidov3Qvs9606 rogid:zdbvJmkrI/zJFL+Enq5jTM1Csdw9606 rigid:wkAPP7CwMyLMTcUikXqcwUWzXKk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P42331-3 uniprotkb:Q9Y6C9 intact:EBI-25408493 intact:EBI-6164522|ensembl:ENSP00000303222|ensembl:ENSP00000495027|uniprotkb:B2R7L8 psi-mi:p423313(display_long)|uniprotkb:ARHGAP25(gene name)|psi-mi:ARHGAP25(display_short)|uniprotkb:KIAA0053(gene name synonym) psi-mi:mtch2_human(display_long)|uniprotkb:MTCH2(gene name)|psi-mi:MTCH2(display_short)|uniprotkb:MIMP(gene name synonym)|uniprotkb:Met-induced mitochondrial protein(gene name synonym)|uniprotkb:HSPC032(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408499|imex:IM-26436-278 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P42331-3(isoform-parent) interpro:IPR018108|interpro:IPR023395|mint:Q9Y6C9|go:"GO:0070585"(protein localization to mitochondrion)|ensembl:ENSG00000109919(gene)|ensembl:ENSG00000285121(gene)|ensembl:ENST00000302503(transcript)|ensembl:ENST00000643223(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|refseq:NP_001304160.1|refseq:NP_001304161.1|refseq:NP_001304162.1|refseq:NP_055157.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:t2rOqCe4heCaixiChlpidov3Qvs9606 rogid:Lbg7MBRn09cRzoYOiSt4g4FjsjA9606 rigid:wkAPP7CwMyLMTcUikXqcwUWzXKk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P42331-3 uniprotkb:Q16576 intact:EBI-25408493 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:p423313(display_long)|uniprotkb:ARHGAP25(gene name)|psi-mi:ARHGAP25(display_short)|uniprotkb:KIAA0053(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408499|imex:IM-26436-278 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P42331-3(isoform-parent) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:t2rOqCe4heCaixiChlpidov3Qvs9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:wkAPP7CwMyLMTcUikXqcwUWzXKk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P42331-3 uniprotkb:Q9NZL9 intact:EBI-25408493 intact:EBI-10317491|uniprotkb:B2R5Y6|uniprotkb:Q6NYC7|uniprotkb:Q27J92|uniprotkb:Q9BS89|uniprotkb:Q9H3E1|uniprotkb:Q3LIE8|uniprotkb:Q9UJ54|uniprotkb:Q1WAI7|uniprotkb:Q567T7|ensembl:ENSP00000325425 psi-mi:p423313(display_long)|uniprotkb:ARHGAP25(gene name)|psi-mi:ARHGAP25(display_short)|uniprotkb:KIAA0053(gene name synonym) psi-mi:mat2b_human(display_long)|uniprotkb:MAT2B(gene name)|psi-mi:MAT2B(display_short)|uniprotkb:Methionine adenosyltransferase II beta(gene name synonym)|uniprotkb:Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase(gene name synonym)|uniprotkb:TGR(gene name synonym)|uniprotkb:MSTP045(orf name)|uniprotkb:Nbla02999(orf name)|uniprotkb:UNQ2435/PRO4995(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408499|imex:IM-26436-278 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P42331-3(isoform-parent) refseq:NP_037415.1|refseq:NP_877725.1|ensembl:ENSG00000038274(gene)|ensembl:ENST00000321757(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0048270"(methionine adenosyltransferase regulator activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005913(dTDP-4-dehydrorhamnose reductase)|interpro:IPR029903|interpro:IPR036291|rcsb pdb:2YDX|rcsb pdb:2YDY|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|reactome:R-HSA-156581|reactome:R-HSA-5689880 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:t2rOqCe4heCaixiChlpidov3Qvs9606 rogid:RxXcRktcrFe+9xm7qgSyZoci4rU9606 rigid:wkAPP7CwMyLMTcUikXqcwUWzXKk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P42331-3 uniprotkb:P31153 intact:EBI-25408493 intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45 psi-mi:p423313(display_long)|uniprotkb:ARHGAP25(gene name)|psi-mi:ARHGAP25(display_short)|uniprotkb:KIAA0053(gene name synonym) psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408499|imex:IM-26436-278 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P42331-3(isoform-parent) refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:t2rOqCe4heCaixiChlpidov3Qvs9606 rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606 rigid:wkAPP7CwMyLMTcUikXqcwUWzXKk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P42331-3 uniprotkb:Q13555 intact:EBI-25408493 intact:EBI-1383465|uniprotkb:O00561|uniprotkb:Q5SWX4|uniprotkb:Q8NIA4|uniprotkb:O15378|uniprotkb:Q13556|uniprotkb:Q5SQZ3|uniprotkb:Q5SQZ4|uniprotkb:Q8N4I3|uniprotkb:Q13279|uniprotkb:Q13282|uniprotkb:Q7KYX5|uniprotkb:A0A0A0MS52|uniprotkb:A0A0A0MT11 psi-mi:p423313(display_long)|uniprotkb:ARHGAP25(gene name)|psi-mi:ARHGAP25(display_short)|uniprotkb:KIAA0053(gene name synonym) psi-mi:kcc2g_human(display_long)|uniprotkb:CAMK(gene name synonym)|uniprotkb:CAMK-II(gene name synonym)|uniprotkb:CAMK2G(gene name)|psi-mi:CAMK2G(display_short)|uniprotkb:CAMKG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408499|imex:IM-26436-278 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P42331-3(isoform-parent) refseq:NP_001213.2|refseq:NP_751909.1|refseq:NP_751913.1|refseq:XP_005270260.1|refseq:NP_001307827.1|refseq:NP_001191421.1|dip:DIP-51315N|mint:Q13555|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014733"(regulation of skeletal muscle adaptation)|go:"GO:0016020"(membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2UX0|rcsb pdb:2V7O|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442729|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:t2rOqCe4heCaixiChlpidov3Qvs9606 rogid:qtCEps5UkV7tprB2QmjCDK5YyIo9606 rigid:wkAPP7CwMyLMTcUikXqcwUWzXKk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P42331-3 uniprotkb:Q13557 intact:EBI-25408493 intact:EBI-351018|intact:EBI-1642546|uniprotkb:Q52PK4|uniprotkb:Q59G21|uniprotkb:Q8N553|uniprotkb:Q9UGH6|uniprotkb:Q9UQE9|uniprotkb:A8MVS8|ensembl:ENSP00000339740|ensembl:ENSP00000507073 psi-mi:p423313(display_long)|uniprotkb:ARHGAP25(gene name)|psi-mi:ARHGAP25(display_short)|uniprotkb:KIAA0053(gene name synonym) psi-mi:kcc2d_human(display_long)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)|uniprotkb:CAMKD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408499|imex:IM-26436-278 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P42331-3(isoform-parent) refseq:NP_001212.2|refseq:NP_742112.1|refseq:NP_742113.1|refseq:NP_742125.1|refseq:NP_742126.1|refseq:NP_742127.1|refseq:NP_001308495.1|refseq:NP_001308502.1|refseq:NP_001308509.1|refseq:NP_001308518.1|ensembl:ENSG00000145349(gene)|ensembl:ENST00000342666(transcript)|ensembl:ENST00000683023(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031432"(titin binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901725"(regulation of histone deacetylase activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13557|rcsb pdb:2VN9|rcsb pdb:2W2C|rcsb pdb:2WEL|rcsb pdb:3GP2|rcsb pdb:5VLO|rcsb pdb:6AYW|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|interpro:IPR032710|refseq:XP_011530591.1|refseq:XP_011530593.1|dip:DIP-33129N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:t2rOqCe4heCaixiChlpidov3Qvs9606 rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI9606 rigid:wkAPP7CwMyLMTcUikXqcwUWzXKk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P22392 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:Q70IA6 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-2558739|uniprotkb:Q96M67|uniprotkb:B4DKP3 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:mob2_human(display_long)|uniprotkb:MOB2(gene name)|psi-mi:MOB2(display_short)|uniprotkb:HCCA2(gene name synonym)|uniprotkb:Mob2 homolog(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001165694.1|refseq:NP_443731.2|interpro:IPR005301(Mob1/phocein)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR036703|mint:Q70IA6 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:bPhfXMdT6x7s05Ufn4VZrMRgcL89606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P15374 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-954554|uniprotkb:Q5TBK8|uniprotkb:Q6IBE9|ensembl:ENSP00000366819|uniprotkb:B2R970 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:uchl3_human(display_long)|uniprotkb:Ubiquitin thioesterase L3(gene name synonym)|uniprotkb:UCHL3(gene name)|psi-mi:UCHL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001257881.1|refseq:NP_005993.1|ensembl:ENSG00000118939(gene)|ensembl:ENST00000377595(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043687"(post-translational protein modification)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|rcsb pdb:1UCH|rcsb pdb:1XD3|rcsb pdb:6ISU|rcsb pdb:6QML|reactome:R-HSA-5689603|reactome:R-HSA-8866652|reactome:R-HSA-8951664|dip:DIP-29135N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:cPnctBpxrgvBKBSaQmhCsyd2nRM9606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:Q01130 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P62745 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-602647|uniprotkb:P01121|uniprotkb:Q5U0H6|uniprotkb:Q7RTN5|uniprotkb:Q7RTR9|uniprotkb:Q9CUV7|uniprotkb:B2R692|ensembl:ENSP00000272233 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:rhob_human(display_long)|uniprotkb:Rho cDNA clone 6(gene name synonym)|uniprotkb:RHOB(gene name)|psi-mi:RHOB(display_short)|uniprotkb:ARH6(gene name synonym)|uniprotkb:ARHB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_004031.1|ensembl:ENSG00000143878(gene)|ensembl:ENST00000272233(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001525"(angiogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010008"(endosome membrane)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62745|rcsb pdb:2FV8|rcsb pdb:6HXU|rcsb pdb:6SGE|reactome:R-HSA-114604|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013026|interpro:IPR003578(Ras small GTPase, Rho type) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:Ek7MCYtpm3JJ78E6nwU/Q9rWZmQ9606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P61586 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175|ensembl:ENSP00000408402|ensembl:ENSP00000503282|ensembl:ENSP00000504180 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001655.1|refseq:NP_001300870.1|dip:DIP-29642N|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|rcsb pdb:3LW8|ensembl:ENSG00000067560(gene)|ensembl:ENST00000418115(transcript)|ensembl:ENST00000445425(transcript)|ensembl:ENST00000678200(transcript)|ensembl:ENST00000679208(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007015"(actin filament organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0017022"(myosin binding)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0001998"(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033688"(regulation of osteoblast proliferation)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0002363"(alpha-beta T cell lineage commitment)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043366"(beta selection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060193"(positive regulation of lipase activity)|go:"GO:0061383"(trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902766"(skeletal muscle satellite cell migration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904695"(positive regulation of vascular associated smooth muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:2RGN|rcsb pdb:3KZ1|go:"GO:0050919"(negative chemotaxis) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P58546 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-1051736|ensembl:ENSP00000376800 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:mtpn_human(display_long)|uniprotkb:Protein V-1(gene name synonym)|uniprotkb:MTPN(gene name)|psi-mi:MTPN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_665807.1|ensembl:ENSG00000105887(gene)|ensembl:ENST00000393085(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010557"(positive regulation of macromolecule biosynthetic process)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000812"(regulation of barbed-end actin filament capping)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P58546|rcsb pdb:3AAA|rcsb pdb:7DF7|rcsb pdb:7DSA|rcsb pdb:7DSB|dip:DIP-50234N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:kdJ8vNN4yI2ye49iYUNAtH538b49606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:Q9ULC4 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-716076|intact:EBI-1048747|uniprotkb:Q502X6|uniprotkb:B4DGY2|ensembl:ENSP00000360367|ensembl:ENSP00000500508 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:mcts1_human(display_long)|uniprotkb:MCTS1(gene name)|psi-mi:MCTS1(display_short)|uniprotkb:MCT1(gene name synonym)|uniprotkb:Multiple copies T-cell malignancies(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001131026.1|refseq:NP_054779.1|ensembl:ENSG00000232119(gene)|ensembl:ENSG00000288295(gene)|ensembl:ENST00000371317(transcript)|ensembl:ENST00000673335(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0040008"(regulation of growth)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002478(PUA)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR015947(PUA-like)|interpro:IPR016437(Translation machinery-associated RNA binding protein, predicted)|interpro:IPR041366|rcsb pdb:3R90|rcsb pdb:5ONS|rcsb pdb:5VYC|rcsb pdb:6MS4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:g630bQeYIEobBeB8zTPwIiGlPys9606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P05114 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P33316 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P04080 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-1051966|ensembl:ENSP00000291568 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:cytb_human(display_long)|uniprotkb:Stefin-B(gene name synonym)|uniprotkb:Liver thiol proteinase inhibitor(gene name synonym)|uniprotkb:CPI-B(gene name synonym)|uniprotkb:CSTB(gene name)|psi-mi:CSTB(display_short)|uniprotkb:CST6(gene name synonym)|uniprotkb:STFB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_000091.1|ensembl:ENSG00000160213(gene)|ensembl:ENST00000291568(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|interpro:IPR018073|mint:P04080|rcsb pdb:1STF|rcsb pdb:2OCT|rcsb pdb:4N6V|reactome:R-HSA-6798695 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:KwR0XgOq6SeHdqxriNE8xIUMmUo9606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRY4 uniprotkb:P23528 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629|ensembl:ENSP00000432660 psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408519|imex:IM-26436-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_005498.1|ensembl:ENSG00000172757(gene)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|ensembl:ENST00000308162(transcript)|ensembl:ENST00000525451(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0031258"(lamellipodium membrane)|dip:DIP-33000N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606 rigid:SD1Kbz0owByAOIxa40hCjCGsH+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:Q9HCD6 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-7954108|uniprotkb:Q9NW88|uniprotkb:Q9HAC3|uniprotkb:Q9NXY9|intact:MINT-7945062|uniprotkb:Q9ULS2|ensembl:ENSP00000387593 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:tanc2_human(display_long)|uniprotkb:TANC2(gene name)|psi-mi:TANC2(display_short)|uniprotkb:KIAA1148(gene name synonym)|uniprotkb:KIAA1636(gene name synonym)|uniprotkb:Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:NP_079461.2|refseq:XP_005257260.1|ensembl:ENSG00000170921(gene)|ensembl:ENST00000424789(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0030424"(axon)|go:"GO:0043197"(dendritic spine)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0099519"(dense core granule cytoskeletal transport)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770 - - comment:mint|comment:homomint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:S8hh+VooYXTnBPORuFNVVfh1YpQ9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:Q8IYB3 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-1055880|uniprotkb:O60585|uniprotkb:Q5VVN4|ensembl:ENSP00000326261 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:srrm1_human(display_long)|uniprotkb:SRRM1(gene name)|psi-mi:SRRM1(display_short)|uniprotkb:SRM160(gene name synonym)|uniprotkb:Ser/Arg-related nuclear matrix protein(gene name synonym)|uniprotkb:SR-related nuclear matrix protein of 160 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:NP_001290377.1|refseq:NP_001290378.1|refseq:NP_005830.2|ensembl:ENSG00000133226(gene)|ensembl:ENST00000323848(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR036483|mint:Q8IYB3|rcsb pdb:1MP1|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013422|reactome:R-HSA-9013418 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:x9vhX2HWCy5mm29U2xVXxj1GJw09606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:Q8TAQ2 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:P31040 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:Q9H792 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-2609701|uniprotkb:Q6ZS78|uniprotkb:Q8TEG7|uniprotkb:Q8NCM3|uniprotkb:Q8NAZ4|ensembl:ENSP00000309230|ensembl:ENSP00000452796|ensembl:ENSP00000507603 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:peak1_human(display_long)|uniprotkb:PEAK1(gene name)|psi-mi:PEAK1(display_short)|uniprotkb:KIAA2002(gene name synonym)|uniprotkb:Sugen kinase 269(gene name synonym)|uniprotkb:Tyrosine-protein kinase SgK269(gene name synonym)|uniprotkb:Pseudopodium-enriched atypical kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:XP_011520335.1|refseq:XP_011520336.1|refseq:XP_011520337.1|refseq:XP_011520338.1|refseq:XP_011520339.1|refseq:XP_011520341.1|refseq:XP_011520340.1|refseq:NP_079052.2|refseq:XP_005254727.1|refseq:XP_005254728.1|refseq:XP_005254730.1|refseq:XP_005254731.1|refseq:XP_005254732.1|ensembl:ENSG00000173517(gene)|ensembl:ENST00000312493(transcript)|ensembl:ENST00000560626(transcript)|ensembl:ENST00000682557(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:6BHC|reactome:R-HSA-9013420|reactome:R-HSA-9013424|ensembl:ENSP00000309230|ensembl:ENSP00000452796|ensembl:ENSP00000507603|dip:DIP-56276N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:z2Q9mOQSYpc1fQJHovBCFsctX749606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:O15394 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-2679983|uniprotkb:B7Z841|uniprotkb:A8MQ06|uniprotkb:Q7Z7F2|ensembl:ENSP00000383392 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:ncam2_human(display_long)|uniprotkb:NCAM21(gene name synonym)|uniprotkb:NCAM2(gene name)|psi-mi:NCAM2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:NP_004531.2|ensembl:ENSG00000154654(gene)|ensembl:ENST00000400546(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2DOC|rcsb pdb:2JLL|rcsb pdb:2KBG|rcsb pdb:2V5T|rcsb pdb:2VAJ|rcsb pdb:2WIM|rcsb pdb:2XY1|rcsb pdb:2XY2|rcsb pdb:2XYC|refseq:XP_016883847.1|dip:DIP-56211N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:GELEcxs6XJOv8k0Z1Yva2ZWZ/FQ9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:Q9NX58 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-713507|uniprotkb:Q6FI78|uniprotkb:Q9NYS1|ensembl:ENSP00000345917|ensembl:ENSP00000397367|uniprotkb:D3DVS4 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:lyar_human(display_long)|uniprotkb:LYAR(gene name)|psi-mi:LYAR(display_short)|uniprotkb:PNAS-5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) ensembl:ENSG00000145220(gene)|ensembl:ENST00000343470(transcript)|ensembl:ENST00000452476(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|interpro:IPR041010|mint:Q9NX58|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZVH|refseq:NP_001139197.1|refseq:NP_060286.1|refseq:XP_011511807.1|refseq:XP_011511808.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:AJ+5B1LahcUlSWQehJ2vxY+8pwY9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:O00479 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-2867693|uniprotkb:Q53XL9|uniprotkb:B2R4I6|ensembl:ENSP00000366798 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:hmgn4_human(display_long)|uniprotkb:HMGN4(gene name)|psi-mi:HMGN4(display_short)|uniprotkb:HMG17L3(gene name synonym)|uniprotkb:NHC(gene name synonym)|uniprotkb:Non-histone chromosomal protein HMG-17-like 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:NP_006344.1|refseq:XP_016865660.1|refseq:XP_016865661.1|refseq:XP_016865662.1|ensembl:ENSG00000182952(gene)|ensembl:ENST00000377575(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:O00479 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:S+sGfUyPi8TfoLIBhSfTTAK9bfA9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:O60832 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-713091|ensembl:ENSP00000358563|uniprotkb:O43845|uniprotkb:Q96G67|uniprotkb:Q9Y505|uniprotkb:F5BSB3 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:dkc1_human(display_long)|uniprotkb:Dyskerin(gene name synonym)|uniprotkb:Nucleolar protein family A member 4(gene name synonym)|uniprotkb:snoRNP protein DKC1(gene name synonym)|uniprotkb:Nopp140-associated protein of 57 kDa(gene name synonym)|uniprotkb:Nucleolar protein NAP57(gene name synonym)|uniprotkb:CBF5 homolog(gene name synonym)|uniprotkb:DKC1(gene name)|psi-mi:DKC1(display_short)|uniprotkb:NOLA4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR032819|interpro:IPR036974|mint:O60832|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901|interpro:IPR002478(PUA)|ensembl:ENSG00000130826(gene)|ensembl:ENST00000369550(transcript)|go:"GO:0000455"(enzyme-directed rRNA pseudouridine synthesis)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003720"(telomerase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990481"(mRNA pseudouridine synthesis)|go:"GO:0006396"(RNA processing)|refseq:NP_001354.1|refseq:NP_001135935.1|refseq:NP_001275676.1|dip:DIP-40645N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:njIdhtX9m37BslwxyAAV/JoRrHo9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:O75128 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-3446582|uniprotkb:A4D257|uniprotkb:B7ZLW9|uniprotkb:B9EGF8|uniprotkb:Q8TCM1|uniprotkb:Q8N304|uniprotkb:A7E2B0|uniprotkb:Q86XA7|uniprotkb:Q504Y4|uniprotkb:Q2T9J3|intact:EBI-28974386|ensembl:ENSP00000265136 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:cobl_human(display_long)|uniprotkb:COBL(gene name)|psi-mi:COBL(display_short)|uniprotkb:KIAA0633(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) ensembl:ENSP00000265136|ensembl:ENST00000395540|ensembl:ENSP00000378910|ensembl:ENST00000395542|ensembl:ENSP00000378912|ensembl:ENST00000441453|ensembl:ENSP00000399500|refseq:XP_011513537.1|refseq:NP_056013.2|refseq:NP_001274365.1|refseq:NP_001274367.1|refseq:NP_001333370.1|refseq:NP_001333371.1|refseq:NP_001333372.1|refseq:NP_001333373.1|ensembl:ENSG00000106078(gene)|ensembl:ENST00000265136(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001726"(ruffle)|go:"GO:0001757"(somite specification)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016020"(membrane)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030903"(notochord development)|go:"GO:0033504"(floor plate development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048565"(digestive tract development)|go:"GO:0048669"(collateral sprouting in absence of injury)|go:"GO:0051639"(actin filament network formation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990357"(terminal web)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR019025|interpro:IPR039895|mint:O75128|rcsb pdb:4PL8 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:mkEX2B5sVoK8CD6RWVVCp912otg9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:Q6P9H4 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-10253274|uniprotkb:Q96N65|uniprotkb:Q5SGD5|uniprotkb:C9IZX4|ensembl:ENSP00000475915 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:cnkr3_human(display_long)|uniprotkb:CNKSR3(gene name)|psi-mi:CNKSR3(display_short)|uniprotkb:CNK homolog protein 3(gene name synonym)|uniprotkb:CNKSR family member 3(gene name synonym)|uniprotkb:MAGI1(gene name synonym)|uniprotkb:Maguin-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:NP_775786.2|ensembl:ENSG00000153721(gene)|ensembl:ENST00000607772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR010599(Connector enhancer of kinase suppressor of ras 2)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:XblyCRyMkFkCnL104LVme415sSc9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:Q8WXI2 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-1045119|uniprotkb:O94976|uniprotkb:Q5JPK4|uniprotkb:Q8WXI1|uniprotkb:B9EG83|uniprotkb:Q5JPN0|ensembl:ENSP00000368824|uniprotkb:B4DGR4|uniprotkb:B7ZLJ1|uniprotkb:E7ESA4 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:cnkr2_human(display_long)|uniprotkb:CNKSR2(gene name)|psi-mi:CNKSR2(display_short)|uniprotkb:CNK2(gene name synonym)|uniprotkb:KIAA0902(gene name synonym)|uniprotkb:KSR2(gene name synonym)|uniprotkb:CNK homolog protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:NP_001162119.1|refseq:NP_055742.2|refseq:NP_001162118.1|refseq:NP_001162120.1|ensembl:ENSG00000149970(gene)|ensembl:ENST00000379510(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099173"(postsynapse organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010599(Connector enhancer of kinase suppressor of ras 2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034|rcsb pdb:2EAN|rcsb pdb:3BS5|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|ensembl:ENSP00000368824|ensembl:ENST00000425654|ensembl:ENSP00000397906|ensembl:ENST00000543067|ensembl:ENSP00000444633|ensembl:ENST00000642359|ensembl:ENSP00000496709|dip:DIP-29736N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:FEIgggNg8LMikG2NZ6LHRD3lKDw9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9C0H5-2 uniprotkb:Q99622 intact:EBI-10973148|ensembl:ENSP00000366522 intact:EBI-2808472|ensembl:ENSP00000229281|ensembl:ENSP00000440602|uniprotkb:B2R4Q6 psi-mi:q9c0h5-2(display_long)|uniprotkb:ARHGAP39(gene name)|psi-mi:ARHGAP39(display_short)|uniprotkb:KIAA1688(gene name synonym) psi-mi:c10_human(display_long)|uniprotkb:C12orf57(gene name)|psi-mi:C12orf57(display_short)|uniprotkb:C10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408549|imex:IM-26436-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11277939(isoform-parent)|ensembl:ENSG00000147799(gene)|ensembl:ENST00000377307(transcript)|uniprotkb:Q9C0H5-2(isoform-parent) refseq:NP_001288763.1|ensembl:ENSG00000111678(gene)|ensembl:ENST00000229281(transcript)|ensembl:ENST00000545581(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021678"(third ventricle development)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050890"(cognition)|interpro:IPR026317|refseq:NP_612434.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sV9MDWLH3a8Bw7hnNGuhSYTDzzo9606 rogid:RQA3V8/ja1T1aBhtzEYvka2r7iQ9606 rigid:qKYFzwr3cRUycEvCwXNHJgi5J9U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:O43318 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008349"(MAP kinase kinase kinase kinase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSG00000135341(gene)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|ensembl:ENST00000369329(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017421(Mitogen-activated protein kinase kinase kinase 7)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27523N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:Q13049 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:Q15750 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-358643|uniprotkb:Q2PP09|intact:EBI-3959873|uniprotkb:Q8IZW2|ensembl:ENSP00000216160 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:tab1_human(display_long)|uniprotkb:TAB1(gene name)|psi-mi:TAB1(display_short)|uniprotkb:MAP3K7IP1(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 refseq:NP_006107.1|refseq:NP_705717.1|ensembl:ENSP00000216160|ensembl:ENST00000331454|ensembl:ENSP00000333049|go:"GO:0003279"(cardiac septum development)|rcsb pdb:7NTI|go:"GO:0003007"(heart morphogenesis)|ensembl:ENSG00000100324(gene)|ensembl:ENST00000216160(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0060976"(coronary vasculature development)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q15750|rcsb pdb:2J4O|rcsb pdb:2POM|rcsb pdb:2POP|rcsb pdb:2YDS|rcsb pdb:2YIY|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4GS6|rcsb pdb:4KA3|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5DIY|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5V5N|rcsb pdb:5VVU|rcsb pdb:7NTH|reactome:R-HSA-168638|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27524N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:28+bzs6bpXJTun4XukxC/7oAYSs9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:Q5T3J3 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:P52756 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|ensembl:ENSP00000343054|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|intact:EBI-16431417 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 ensembl:ENSG00000003756(gene)|ensembl:ENST00000347869(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033094|interpro:IPR034991|interpro:IPR034993|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|reactome:R-HSA-72163|refseq:NP_005769.1|refseq:XP_016860992.1|dip:DIP-47277N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:P28749 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-971402|uniprotkb:Q4VXA0|uniprotkb:Q8N5K6|uniprotkb:Q9H1L5|uniprotkb:Q9H1M1|uniprotkb:A8K2W5|ensembl:ENSP00000362768 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:rbl1_human(display_long)|uniprotkb:RBL1(gene name)|psi-mi:RBL1(display_short)|uniprotkb:pRb1(gene name synonym)|uniprotkb:107 kDa retinoblastoma-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 refseq:NP_002886.2|refseq:NP_899662.1|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR028310|interpro:IPR036915|mint:P28749|rcsb pdb:1H28|rcsb pdb:4YOO|rcsb pdb:4YOS|rcsb pdb:4YOZ|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69205|reactome:R-HSA-69231|ensembl:ENSG00000080839(gene)|ensembl:ENST00000373664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0051302"(regulation of cell division)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|dip:DIP-148N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:1tVe9Uv2ltXGbEc8qC1fNPEAYiE9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:P61289 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:Q8IWI9 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:Q7Z353 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-1052734|uniprotkb:Q5JZB4|uniprotkb:Q96NK7|uniprotkb:A8K1Y5|uniprotkb:B7ZL18|ensembl:ENSP00000297977|ensembl:ENSP00000362272 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:hdx_human(display_long)|uniprotkb:HDX(gene name)|psi-mi:HDX(display_short)|uniprotkb:CXorf43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 refseq:NP_001170949.1|refseq:NP_001170950.1|refseq:NP_653258.2|refseq:XP_011529165.1|refseq:XP_011529166.1|refseq:XP_006724682.1|ensembl:ENSG00000165259(gene)|ensembl:ENST00000297977(transcript)|ensembl:ENST00000373177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|rcsb pdb:2DA4|refseq:XP_016884763.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:nhMJWu8xnF2FDhtzcHcpjLftNjE9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:Q6ZV73 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-3959469|uniprotkb:Q9NUR8|uniprotkb:Q96D44|uniprotkb:Q7Z2Z7|uniprotkb:Q9P2I5|uniprotkb:Q6ZR53|ensembl:ENSP00000344446 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:fgd6_human(display_long)|uniprotkb:FGD6(gene name)|psi-mi:FGD6(display_short)|uniprotkb:KIAA1362(gene name synonym)|uniprotkb:ZFYVE24(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 refseq:NP_060821.3|ensembl:ENSG00000180263(gene)|ensembl:ENST00000343958(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR037743|mint:Q6ZV73 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:tGTBRM2CAnj8C/lEzaVA7vqwRfs9606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80YF9 uniprotkb:Q9Y2J2 intact:EBI-1210140|uniprotkb:Q6P7W6|ensembl:ENSMUSP00000038412|ensembl:ENSMUSP00000146602|ensembl:ENSMUSP00000146767 intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158|uniprotkb:B7Z4I5|uniprotkb:F5GX05 psi-mi:rhg33_mouse(display_long)|uniprotkb:Arhgap33(gene name)|psi-mi:Arhgap33(display_short)|uniprotkb:Tcgap(gene name synonym)|uniprotkb:Snx26(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 33(gene name synonym)|uniprotkb:Tc10/CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:Sorting nexin-26(gene name synonym) psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408581|imex:IM-26436-194 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_839983.1|refseq:NP_001276599.1|refseq:NP_001276611.1|refseq:XP_006539951.1|ensembl:ENSMUSG00000036882(gene)|ensembl:ENSMUST00000044338(transcript)|ensembl:ENSMUST00000207860(transcript)|ensembl:ENSMUST00000208538(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035510|interpro:IPR036028|interpro:IPR036871|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406 refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397(gene)|ensembl:ENST00000341928(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XmvU4f9QHiQn44fw7pMraA74KAw10090 rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606 rigid:TNn7AABsPn5/AFp0PwsKAc3dLPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:O75431 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-7415268|uniprotkb:Q53SQ2|uniprotkb:Q5M7Z6|uniprotkb:A8JZZ4|intact:MINT-3001232|intact:MINT-4876050|uniprotkb:Q53S50|ensembl:ENSP00000249442|uniprotkb:Q8IZ68 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:mtx2_human(display_long)|uniprotkb:MTX2(gene name)|psi-mi:MTX2(display_short)|uniprotkb:Mitochondrial outer membrane import complex protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_001306026.1|refseq:NP_001306027.1|refseq:NP_001006636.1|refseq:NP_006545.1|ensembl:ENSG00000128654(gene)|ensembl:ENST00000249442(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0015031"(protein transport)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:O75431|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex) - - comment:mint|function:Involved in transport of proteins into the mitochondrion figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:M4zfGX8gfFUFW7xYoXeEzA2UCSM9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q6PJI9 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-2515073|intact:EBI-28967178|ensembl:ENSP00000262144|uniprotkb:Q9HA43|uniprotkb:Q96PW5|uniprotkb:B3KRC3|uniprotkb:Q9BSW6|uniprotkb:Q71RE7 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:wdr59_human(display_long)|uniprotkb:WDR59(gene name)|psi-mi:WDR59(display_short)|uniprotkb:KIAA1923(gene name synonym)|uniprotkb:WD repeat-containing protein 59(gene name synonym)|uniprotkb:FP977(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) ensembl:ENSP00000262144|ensembl:ENST00000616369|ensembl:ENSP00000482446|ensembl:ENSG00000103091(gene)|ensembl:ENST00000262144(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0061700"(GATOR2 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR006575(RWD)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039456|reactome:R-HSA-9639288|mint:Q6PJI9|refseq:NP_001311100.1|refseq:NP_085058.3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:7yMOhbv8kjVuL8I+Zs+8fLF933k9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q9NZR1 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-4289968|uniprotkb:B4DEW6|ensembl:ENSP00000249700 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:tmod2_human(display_long)|uniprotkb:TMOD2(gene name)|psi-mi:TMOD2(display_short)|uniprotkb:NTMOD(gene name synonym)|uniprotkb:Neuronal tropomodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) ensembl:ENSG00000128872(gene)|ensembl:ENST00000249700(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030426"(growth cone)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051694"(pointed-end actin filament capping)|interpro:IPR004934(Tropomodulin)|interpro:IPR030130|interpro:IPR032675|reactome:R-HSA-390522|refseq:NP_001136357.1|refseq:NP_055363.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:km9yOQf3wlXkMxXa/wKFxquWej09606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:P28289 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-2659631|uniprotkb:B2RB77|uniprotkb:Q5T7W3|uniprotkb:Q9BUF1|ensembl:ENSP00000259365|ensembl:ENSP00000378637|intact:EBI-10965302 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:tmod1_human(display_long)|uniprotkb:Erythrocyte tropomodulin(gene name synonym)|uniprotkb:D9S57E(gene name synonym)|uniprotkb:TMOD(gene name synonym)|uniprotkb:TMOD1(gene name)|psi-mi:TMOD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_001159588.1|refseq:NP_003266.1|ensembl:ENST00000259365(transcript)|ensembl:ENST00000395211(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0070307"(lens fiber cell development)|interpro:IPR004934(Tropomodulin)|interpro:IPR030135|interpro:IPR032675|mint:P28289|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4Z8G|rcsb pdb:4Z94|reactome:R-HSA-390522|ensembl:ENSG00000136842(gene) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:xbmnoh2E0cuP4ZYmnhlOo8QDnHw9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q8WVM0 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-2615570|uniprotkb:Q9Y384|uniprotkb:Q05DR0|ensembl:ENSP00000356134 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:tfb1m_human(display_long)|uniprotkb:"S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1"(gene name synonym)|uniprotkb:Mitochondrial 12S rRNA dimethylase 1(gene name synonym)|uniprotkb:Mitochondrial transcription factor B1(gene name synonym)|uniprotkb:CGI-75(orf name)|uniprotkb:TFB1M(gene name)|psi-mi:TFB1M(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_057104.2|ensembl:ENSG00000029639(gene)|ensembl:ENST00000367166(transcript)|go:"GO:0000154"(rRNA modification)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0031167"(rRNA methylation)|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR023165|interpro:IPR029063|rcsb pdb:6AAX|rcsb pdb:6AJK|reactome:R-HSA-2151201|reactome:R-HSA-6793080 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:aw07ohZ/7xuqVv7NvbMOqCTMayM9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q99584 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-721909|uniprotkb:Q52PI9|uniprotkb:Q6FGF8|ensembl:ENSP00000344822|ensembl:ENSP00000376398|ensembl:ENSP00000376399|ensembl:ENSP00000392767|ensembl:ENSP00000507299 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:s10ad_human(display_long)|uniprotkb:S100 calcium-binding protein A13(gene name synonym)|uniprotkb:S100A13(gene name)|psi-mi:S100A13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_001019381.1|refseq:NP_001019382.1|refseq:NP_001019383.1|refseq:NP_001019384.1|refseq:NP_005970.1|refseq:XP_011508164.1|refseq:XP_011508165.1|refseq:XP_011508166.1|refseq:XP_005245491.1|refseq:XP_016857523.1|refseq:XP_016857524.1|refseq:XP_016857525.1|ensembl:ENSG00000189171(gene)|ensembl:ENST00000339556(transcript)|ensembl:ENST00000392622(transcript)|ensembl:ENST00000392623(transcript)|ensembl:ENST00000440685(transcript)|ensembl:ENST00000476133(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028487|rcsb pdb:1YUR|rcsb pdb:1YUS|rcsb pdb:1YUT|rcsb pdb:1YUU|rcsb pdb:2EGD|rcsb pdb:2H2K|rcsb pdb:2K8M|rcsb pdb:2KI4|rcsb pdb:2KI6|rcsb pdb:2KOT|rcsb pdb:2L5X|rcsb pdb:2LE9 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:TSQW3OvBldoNzNN2g6uxgUJAjUg9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q96P16 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q96SB3 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-351275|uniprotkb:Q8TCR9|intact:EBI-28984643|ensembl:ENSP00000478767|intact:EBI-4401886|uniprotkb:D3DTX6 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:neb2_human(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:PPP1R9B(gene name)|psi-mi:PPP1R9B(display_short)|uniprotkb:PPP1R6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) ensembl:ENSG00000108819(gene)|ensembl:ENST00000612501(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035094"(response to nicotine)|go:"GO:0035690"|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060179"(male mating behavior)|go:"GO:0061458"(reproductive system development)|go:"GO:0071315"(cellular response to morphine)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097338"(response to clozapine)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903119"(protein localization to actin cytoskeleton)|go:"GO:1904372"(positive regulation of protein localization to actin cortical patch)|go:"GO:1904373"(response to kainic acid)|go:"GO:1904386"(response to L-phenylalanine derivative)|go:"GO:1990778"(protein localization to cell periphery)|go:"GO:1990780"(cytoplasmic side of dendritic spine plasma membrane)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029921|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q96SB3|ensembl:ENSP00000478767|refseq:NP_115984.3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:X6fQLpaYhXCqzRlQNEoX67P/HbU9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q9UNP9 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q96PX9 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-11741362|ensembl:ENSP00000283426 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q9HBH1 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-5460681|uniprotkb:Q8WUN6|ensembl:ENSP00000288022 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:defm_human(display_long)|uniprotkb:PDF(gene name)|psi-mi:PDF(display_short)|uniprotkb:PDF1A(gene name synonym)|uniprotkb:Polypeptide deformylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_071736.1|ensembl:ENST00000288022(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0018206"(peptidyl-methionine modification)|ensembl:ENSG00000258429(gene)|go:"GO:0031365"(N-terminal protein amino acid modification)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR023635|interpro:IPR036821|rcsb pdb:3G5K|rcsb pdb:3G5P - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:StM3o3nhBlrCad9VRPWUt48jgaM9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q8NC60 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-717871|uniprotkb:Q8N7L6|uniprotkb:Q9BSQ9|ensembl:ENSP00000264230 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:noa1_human(display_long)|uniprotkb:NOA1(gene name)|psi-mi:NOA1(display_short)|uniprotkb:C4orf14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_115689.1|ensembl:ENSG00000084092(gene)|ensembl:ENST00000264230(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0010941"(regulation of cell death)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043457"(regulation of cellular respiration)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:lynfPNtWZ/q7Df9/hpwiyIjUD2Y9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q6NZ67 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-1052566|uniprotkb:Q96CG4|intact:EBI-2555069|ensembl:ENSP00000281871 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:mzt2b_human(display_long)|uniprotkb:MZT2B(gene name)|psi-mi:MZT2B(display_short)|uniprotkb:FAM128B(gene name synonym)|uniprotkb:MOZART2B(gene name synonym)|uniprotkb:Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_079305.2|ensembl:ENSG00000152082(gene)|ensembl:ENST00000281871(transcript)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|interpro:IPR024332|mint:Q6NZ67|reactome:R-HSA-380270|reactome:R-HSA-380320 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:zjtQDl3ebeUtbVBixZvPf25VcxQ9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q9Y4I1 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-1054086|uniprotkb:O60653|uniprotkb:Q07902|uniprotkb:Q16249|uniprotkb:Q9UE30|uniprotkb:Q9UE31|uniprotkb:A8MZC5|ensembl:ENSP00000382177 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:myo5a_human(display_long)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym)|uniprotkb:Myosin heavy chain 12(gene name synonym)|uniprotkb:Myoxin(gene name synonym)|uniprotkb:MYO5A(gene name)|psi-mi:MYO5A(display_short)|uniprotkb:MYH12(gene name synonym)|uniprotkb:Myosin-12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_000250.3|refseq:XP_005254454.1|ensembl:ENSG00000197535(gene)|ensembl:ENST00000399231(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030426"(growth cone)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032433"(filopodium tip)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|interpro:IPR037988|mint:Q9Y4I1|rcsb pdb:4D07|rcsb pdb:4J5L|rcsb pdb:4LLI|rcsb pdb:4LX1|rcsb pdb:4LX2|rcsb pdb:5JCY|rcsb pdb:5JCZ|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-264876|reactome:R-HSA-9664422 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:z4bbPG/RrXSmBWT6I0nbIztGp809606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q6WCQ1 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-1022605|uniprotkb:Q3KQZ5|uniprotkb:Q5FB94|uniprotkb:Q6DHW2|uniprotkb:Q7Z5Y2|uniprotkb:Q8N390|uniprotkb:Q96G40|ensembl:ENSP00000342379 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:mprip_human(display_long)|uniprotkb:MRIP(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym)|uniprotkb:MPRIP(gene name)|psi-mi:MPRIP(display_short)|uniprotkb:KIAA0864(gene name synonym)|uniprotkb:RHOIP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) ensembl:ENSG00000133030(gene)|ensembl:ENST00000341712(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q6WCQ1|reactome:R-HSA-6802952|refseq:NP_055949.2|refseq:NP_958431.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:QoGbbg2ehuQogDM1Dlxzw6xj59s9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q96II8 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q86WA8 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-2513996|ensembl:ENSP00000285737|uniprotkb:Q96K43|uniprotkb:Q8N3B9|uniprotkb:Q0D2H6|uniprotkb:Q8NCE9|uniprotkb:B7ZKL7 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:lonp2_human(display_long)|uniprotkb:LONP2(gene name)|psi-mi:LONP2(display_short)|uniprotkb:LONP(gene name synonym)|uniprotkb:Lon protease-like protein 2(gene name synonym)|uniprotkb:Peroxisomal Lon protease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) ensembl:ENSG00000102910(gene)|ensembl:ENST00000285737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008233"(peptidase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0019899"(enzyme binding)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027501|reactome:R-HSA-390471|reactome:R-HSA-9033241|refseq:NP_001287877.1|refseq:NP_113678.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:WyZglDz2aZOpnRVtWTrAf62G0pA9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q16352 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-366258|uniprotkb:Q9BRC5|uniprotkb:B1AQK0|ensembl:ENSP00000358865 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:ainx_human(display_long)|uniprotkb:INA(gene name)|psi-mi:INA(display_short)|uniprotkb:66 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 5(gene name synonym)|uniprotkb:NEF5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_116116.1|ensembl:ENSG00000148798(gene)|ensembl:ENST00000369849(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005883"(neurofilament)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027703|interpro:IPR039008|mint:Q16352 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:HXC2d0wajSa0s9r7b4qtpqi3g+s9606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q9P000 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-1550510|uniprotkb:Q9H0R0|uniprotkb:Q96FI2|uniprotkb:E9PAN2|ensembl:ENSP00000263401 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:comd9_human(display_long)|uniprotkb:COMMD9(gene name)|psi-mi:COMMD9(display_short)|uniprotkb:HSPC166(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_054905.2|refseq:NP_001294866.1|ensembl:ENSG00000110442(gene)|ensembl:ENST00000263401(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006814"(sodium ion transport)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR017920|interpro:IPR037360|rcsb pdb:4NKN|rcsb pdb:4OE9|rcsb pdb:6BP6|reactome:R-HSA-6798695|reactome:R-HSA-8951664 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:2MhNQZU+OGXGZ2nuSi1AS8+bpz09606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q9P2M7 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-79537|intact:EBI-28986579|ensembl:ENSP00000271636|uniprotkb:Q5T386|uniprotkb:Q9NR25|uniprotkb:A6H8L3|uniprotkb:A7MD22 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:cing_human(display_long)|uniprotkb:CGN(gene name)|psi-mi:CGN(display_short)|uniprotkb:KIAA1319(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408609|imex:IM-26436-294 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) ensembl:ENSG00000143375(gene)|ensembl:ENST00000271636(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016459"(myosin complex)|go:"GO:0030054"(cell junction)|go:"GO:0045296"(cadherin binding)|interpro:IPR002928(Myosin tail)|mint:Q9P2M7|reactome:R-HSA-2173791|refseq:NP_065821.1|ensembl:ENSP00000271636|refseq:XP_005245422.1|dip:DIP-30947N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:RJ4soprXOGUAlMLVIikuoeMs3v09606 rigid:Sp6nn+NWRJjBIk/A3DHhOMx/s58 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BN58-3 uniprotkb:Q6ZW31 intact:EBI-25408701 intact:EBI-11603303|uniprotkb:Q7L2I8|uniprotkb:Q8N6J2|uniprotkb:Q9H8K4|ensembl:ENSP00000341489 psi-mi:q8bn583(display_long)|uniprotkb:Arhgap28(gene name)|psi-mi:Arhgap28(display_short)|uniprotkb:Kiaa1314(gene name synonym) psi-mi:syde1_human(display_long)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408707|imex:IM-26436-76 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8BN58-3(isoform-parent) refseq:NP_001287839.1|refseq:NP_149014.3|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0016477"(cell migration)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-9013148|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Y6++JdU1pZjBm59V2SIyoJojh9w10090 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rigid:dKy1mFcutMSRqFGeu+Pp0/rZs2o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BN58-3 uniprotkb:P35241 intact:EBI-25408701 intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7 psi-mi:q8bn583(display_long)|uniprotkb:Arhgap28(gene name)|psi-mi:Arhgap28(display_short)|uniprotkb:Kiaa1314(gene name synonym) psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408707|imex:IM-26436-76 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8BN58-3(isoform-parent) ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Y6++JdU1pZjBm59V2SIyoJojh9w10090 rogid:75lzbINdL0deHtiWY7IwioSh5749606 rigid:dKy1mFcutMSRqFGeu+Pp0/rZs2o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BN58-3 uniprotkb:P26038 intact:EBI-25408701 intact:EBI-528768|ensembl:ENSP00000353408 psi-mi:q8bn583(display_long)|uniprotkb:Arhgap28(gene name)|psi-mi:Arhgap28(display_short)|uniprotkb:Kiaa1314(gene name synonym) psi-mi:moes_human(display_long)|uniprotkb:Membrane-organizing extension spike protein(gene name synonym)|uniprotkb:MSN(gene name)|psi-mi:MSN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408707|imex:IM-26436-76 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8BN58-3(isoform-parent) refseq:NP_002435.1|ensembl:ENSG00000147065(gene)|ensembl:ENST00000360270(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001931"(uropod)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005925"(focal adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0042098"(T cell proliferation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070489"(T cell aggregation)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009986"(cell surface)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0072678"(T cell migration)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000401"(regulation of lymphocyte migration)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P26038|rcsb pdb:1E5W|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016323"(basolateral plasma membrane)|rcsb pdb:1EF1|rcsb pdb:1SGH|rcsb pdb:6TXQ|go:"GO:0016324"(apical plasma membrane)|rcsb pdb:6TXS|reactome:R-HSA-437239|reactome:R-HSA-8950505|reactome:R-HSA-9662360|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-9662361|go:"GO:0019901"(protein kinase binding)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0031143"(pseudopodium)|go:"GO:0031528"(microvillus membrane)|dip:DIP-33841N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Y6++JdU1pZjBm59V2SIyoJojh9w10090 rogid:XYzuC8VtaVyNYyZ2G5wVbxyPPww9606 rigid:dKy1mFcutMSRqFGeu+Pp0/rZs2o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BN58-3 uniprotkb:P15311 intact:EBI-25408701 intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042 psi-mi:q8bn583(display_long)|uniprotkb:Arhgap28(gene name)|psi-mi:Arhgap28(display_short)|uniprotkb:Kiaa1314(gene name synonym) psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408707|imex:IM-26436-76 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8BN58-3(isoform-parent) ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Y6++JdU1pZjBm59V2SIyoJojh9w10090 rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606 rigid:dKy1mFcutMSRqFGeu+Pp0/rZs2o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BN58-3 uniprotkb:Q9NRY4 intact:EBI-25408701 intact:EBI-766200|uniprotkb:Q14452|uniprotkb:Q9C0E1|uniprotkb:A7E2A4|ensembl:ENSP00000385720|ensembl:ENSP00000483730|ensembl:ENSP00000500409 psi-mi:q8bn583(display_long)|uniprotkb:Arhgap28(gene name)|psi-mi:Arhgap28(display_short)|uniprotkb:Kiaa1314(gene name synonym) psi-mi:rhg35_human(display_long)|uniprotkb:Glucocorticoid receptor repression factor 1(gene name synonym)|uniprotkb:Rho GAP p190A(gene name synonym)|uniprotkb:Glucocorticoid receptor DNA-binding factor 1(gene name synonym)|uniprotkb:GRF1(gene name synonym)|uniprotkb:KIAA1722(gene name synonym)|uniprotkb:ARHGAP35(gene name)|psi-mi:ARHGAP35(display_short)|uniprotkb:GRLF1(gene name synonym)|uniprotkb:P190A(gene name synonym)|uniprotkb:p190ARHOGAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408707|imex:IM-26436-76 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8BN58-3(isoform-parent) refseq:NP_004482.4|refseq:XP_016882203.1|dip:DIP-34578N|ensembl:ENSG00000160007(gene)|ensembl:ENST00000404338(transcript)|ensembl:ENST00000614079(transcript)|ensembl:ENST00000672722(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003677"(DNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030879"(mammary gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0097485"(neuron projection guidance)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|rcsb pdb:2K85|rcsb pdb:3C5H|rcsb pdb:3FK2|rcsb pdb:6PXC|rcsb pdb:6WAY|reactome:R-HSA-416550|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Y6++JdU1pZjBm59V2SIyoJojh9w10090 rogid:QvhQwcov1A+SZ0qmVnhVebJ30rg9606 rigid:dKy1mFcutMSRqFGeu+Pp0/rZs2o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BN58-3 uniprotkb:Q2M1Z3 intact:EBI-25408701 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 psi-mi:q8bn583(display_long)|uniprotkb:Arhgap28(gene name)|psi-mi:Arhgap28(display_short)|uniprotkb:Kiaa1314(gene name synonym) psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408707|imex:IM-26436-76 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8BN58-3(isoform-parent) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Y6++JdU1pZjBm59V2SIyoJojh9w10090 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rigid:dKy1mFcutMSRqFGeu+Pp0/rZs2o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:Q8N4B1 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-7310488|uniprotkb:Q96MH8|intact:MINT-6778621|uniprotkb:Q6PJL9|uniprotkb:J3KP50|ensembl:ENSP00000447353|ensembl:ENSP00000449994|ensembl:ENSP00000507123 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:sesq1_human(display_long)|uniprotkb:PHETA1(gene name)|psi-mi:PHETA1(display_short)|uniprotkb:27 kDa inositol polyphosphate phosphatase-interacting protein A(gene name synonym)|uniprotkb:FAM109A(gene name synonym)|uniprotkb:PH domain-containing endocytic trafficking adaptor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:XP_011536278.1|refseq:NP_001171467.1|refseq:NP_653272.2|refseq:NP_001171468.1|refseq:XP_016874372.1|ensembl:ENSG00000198324(gene)|ensembl:ENST00000547838(transcript)|ensembl:ENST00000548163(transcript)|ensembl:ENST00000683047(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055037"(recycling endosome)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:3QIS|refseq:XP_006719320.1 - - comment:mint|comment:homomint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:fCyEKQCd+OfWDEZsr6XfMsrHnoQ9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P62304 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:Q9BWJ5 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-2555428|uniprotkb:Q7RTV1|uniprotkb:B2R568|ensembl:ENSP00000356541 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:sf3b5_human(display_long)|uniprotkb:SF3B10(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:SF3B5(gene name)|psi-mi:SF3B5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_112577.1|ensembl:ENSG00000169976(gene)|ensembl:ENST00000367569(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q9BWJ5|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5Z57 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:wuQBsSytGhSg64IQSmEJXe+26zQ9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P06702 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P05109 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:Q9NRW1 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-1760079|uniprotkb:D3DND3|uniprotkb:B2R5Z9|uniprotkb:Q92929|uniprotkb:B7Z337|ensembl:ENSP00000285208|ensembl:ENSP00000437797 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:rab6b_human(display_long)|uniprotkb:RAB6B(gene name)|psi-mi:RAB6B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:XP_011511195.1|refseq:NP_057661.3|ensembl:ENSG00000154917(gene)|ensembl:ENST00000285208(transcript)|ensembl:ENST00000543906(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0098793"(presynapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9NRW1|rcsb pdb:2E9S|rcsb pdb:2FE4|rcsb pdb:2FFQ|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:GmhjkLknjr8fxoUBxNx5ak5S/hQ9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P20340 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-1052826|uniprotkb:Q5U0A8|uniprotkb:Q9UBE4|uniprotkb:A8K133|uniprotkb:Q1W5D8|uniprotkb:B7Z772|uniprotkb:F5H668|ensembl:ENSP00000336850 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:rab6a_human(display_long)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_002860.2|refseq:NP_942599.1|refseq:NP_001230648.1|refseq:NP_001230647.1|ensembl:ENSG00000175582(gene)|ensembl:ENST00000336083(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0018125"(peptidyl-cysteine methylation)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0072385"(minus-end-directed organelle transport along microtubule)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20340|rcsb pdb:1YZQ|rcsb pdb:2GIL|rcsb pdb:3BBP|rcsb pdb:3CWZ|rcsb pdb:4DKX|rcsb pdb:5LEF|reactome:R-HSA-1912420|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-39668N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P20339 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-399437|uniprotkb:B4DJA5|intact:EBI-1048179|uniprotkb:Q6FI44|ensembl:ENSP00000273047 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:rab5a_human(display_long)|uniprotkb:RAB5A(gene name)|psi-mi:RAB5A(display_short)|uniprotkb:RAB5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_004153.2|refseq:NP_001278977.1|dip:DIP-380N|ensembl:ENSG00000144566(gene)|ensembl:ENST00000273047(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098559"(cytoplasmic side of early endosome membrane)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20339|rcsb pdb:1N6H|rcsb pdb:1N6I|rcsb pdb:1N6K|rcsb pdb:1N6L|rcsb pdb:1N6N|rcsb pdb:1N6O|rcsb pdb:1N6P|rcsb pdb:1N6R|rcsb pdb:1R2Q|rcsb pdb:1TU3|rcsb pdb:1TU4|rcsb pdb:3MJH|rcsb pdb:4Q9U|rcsb pdb:7BL1|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9636383|reactome:R-HSA-983231 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:SgowwV7QSVCvfsqSDE+6CHmPmKA9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:Q9H0U4 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-1045214|ensembl:ENSP00000310226|uniprotkb:A8K7S1 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:rab1b_human(display_long)|uniprotkb:RAB1B(gene name)|psi-mi:RAB1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) ensembl:ENSG00000174903(gene)|ensembl:ENST00000311481(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0019068"(virion assembly)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_112243.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9H0U4|rcsb pdb:3JZA|rcsb pdb:3NKV|rcsb pdb:4HLQ|rcsb pdb:4I1O|rcsb pdb:5O74|rcsb pdb:5SZH|rcsb pdb:5SZK|rcsb pdb:6SKU|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42462N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:EI6DHq7xCboSkoqGY5NmVY4Iqf09606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P62820 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286|ensembl:ENSP00000497078 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_004152.1|refseq:NP_056358.1|ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0019068"(virion assembly)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045296"(cadherin binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-1063N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:Q9NW61 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-1057560|intact:EBI-5774167|uniprotkb:B3KUQ9|uniprotkb:D6W604|ensembl:ENSP00000318075|ensembl:ENSP00000465391 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:pkhj1_human(display_long)|uniprotkb:PLEKHJ1(gene name)|psi-mi:PLEKHJ1(display_short)|uniprotkb:GNRPX(gene name synonym)|uniprotkb:Guanine nucleotide-releasing protein x(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_060519.1|ensembl:ENSG00000104886(gene)|ensembl:ENST00000326631(transcript)|ensembl:ENST00000589097(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0007032"(endosome organization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0055037"(recycling endosome)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:S+dCRMRJ5DkeCUDUuXfDsn6LAf49606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P02788 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:Q3MHD2 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P26583 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-1057009|uniprotkb:Q5U072|uniprotkb:D3DP37|uniprotkb:B2R4K8|ensembl:ENSP00000296503|ensembl:ENSP00000393448|ensembl:ENSP00000404912 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:hmgb2_human(display_long)|uniprotkb:HMGB2(gene name)|psi-mi:HMGB2(display_short)|uniprotkb:HMG2(gene name synonym)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_001124160.1|refseq:NP_001124161.1|refseq:NP_002120.1|ensembl:ENSG00000164104(gene)|ensembl:ENST00000296503(transcript)|ensembl:ENST00000438704(transcript)|ensembl:ENST00000446922(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032075"(positive regulation of nuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR036910|mint:P26583|reactome:R-HSA-140342 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:ACzaSeIwT3vM4ZgpCSSlzA6nd4U9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P09429 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P08246 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-986345|uniprotkb:P09649|uniprotkb:Q6B0D9|uniprotkb:Q6LDP5|ensembl:ENSP00000263621|ensembl:ENSP00000466090|ensembl:ENSP00000480128|ensembl:ENSP00000488075 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:elne_human(display_long)|uniprotkb:Elastase-2(gene name synonym)|uniprotkb:ELANE(gene name)|psi-mi:ELANE(display_short)|uniprotkb:PMN elastase(gene name synonym)|uniprotkb:Bone marrow serine protease(gene name synonym)|uniprotkb:Medullasin(gene name synonym)|uniprotkb:Human leukocyte elastase(gene name synonym)|uniprotkb:ELA2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) ensembl:ENSG00000197561(gene)|ensembl:ENSG00000277571(gene)|ensembl:ENST00000263621(transcript)|ensembl:ENST00000590230(transcript)|ensembl:ENST00000615489(transcript)|ensembl:ENST00000632488(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001878"(response to yeast)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002812"(biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008201"(heparin binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0009411"(response to UV)|go:"GO:0009986"(cell surface)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019955"(cytokine binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030141"(secretory granule)|go:"GO:0030163"(protein catabolic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070269"(pyroptosis)|go:"GO:0070945"(neutrophil-mediated killing of gram-negative bacterium)|go:"GO:0070947"(neutrophil-mediated killing of fungus)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P08246|rcsb pdb:1B0F|rcsb pdb:1H1B|rcsb pdb:1HNE|rcsb pdb:1PPF|rcsb pdb:1PPG|rcsb pdb:2RG3|rcsb pdb:2Z7F|rcsb pdb:3Q76|rcsb pdb:3Q77|rcsb pdb:4NZL|rcsb pdb:4WVP|rcsb pdb:5A09|rcsb pdb:5A0A|rcsb pdb:5A0B|rcsb pdb:5A0C|rcsb pdb:5A8X|rcsb pdb:5A8Y|rcsb pdb:5A8Z|rcsb pdb:5ABW|rcsb pdb:6E69|rcsb pdb:6F5M|rcsb pdb:6SMA|rcsb pdb:7CBK|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-5620971|reactome:R-HSA-6798695|reactome:R-HSA-6803157|reactome:R-HSA-977606|refseq:NP_001963.1|refseq:XP_011526078.1|refseq:XP_011526077.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:0XCflWhF346d7Dy2+ENeMyDHPmA9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P08311 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-5462635|uniprotkb:Q6IBJ6|uniprotkb:Q9UCA5|uniprotkb:Q9UCU6|ensembl:ENSP00000216336 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:catg_human(display_long)|uniprotkb:CTSG(gene name)|psi-mi:CTSG(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_001902.1|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030141"(secretory granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035590"(purinergic nucleotide receptor signaling pathway)|ensembl:ENSG00000100448(gene)|ensembl:ENST00000216336(transcript)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0006955"(immune response)|go:"GO:0008201"(heparin binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070946"(neutrophil-mediated killing of gram-positive bacterium)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P08311|rcsb pdb:1AU8|reactome:R-HSA-448706|rcsb pdb:1CGH|rcsb pdb:1KYN|rcsb pdb:1T32|rcsb pdb:6VTM|reactome:R-HSA-6798695|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-2022377|reactome:R-HSA-381426|reactome:R-HSA-6803157|reactome:R-HSA-9635465|reactome:R-HSA-9660826 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:Q3qTg9KcvP4oI+A/QOUqk7ahWMU9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:Q9H7C9 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-10308705|uniprotkb:Q9Y6B1|uniprotkb:Q96AQ4|ensembl:ENSP00000377078|ensembl:ENSP00000431808 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:aamdc_human(display_long)|uniprotkb:AAMDC(gene name)|psi-mi:AAMDC(display_short)|uniprotkb:Adipogenesis associated Mth938 domain-containing protein(gene name synonym)|uniprotkb:C11orf67(gene name synonym)|uniprotkb:PTD015(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_001303886.1|refseq:NP_001303889.1|refseq:NP_001303890.1|refseq:NP_001303891.1|refseq:NP_078960.1|refseq:XP_011543271.1|ensembl:ENSG00000087884(gene)|ensembl:ENST00000393427(transcript)|ensembl:ENST00000526415(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045600"(positive regulation of fat cell differentiation)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034096|interpro:IPR036748|mint:Q9H7C9|rcsb pdb:2AB1|rcsb pdb:2Q4Q - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:K1kfbdCxyGTAglEl+pDfu4NjjMs9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:Q9H3K6 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-1642537|uniprotkb:A1L454|uniprotkb:A7YDY3|ensembl:ENSP00000331127|ensembl:ENSP00000498355 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:bola2_human(display_long)|uniprotkb:BOLA2(gene name)|psi-mi:BOLA2(display_short)|uniprotkb:BOLA2B(gene name)|psi-mi:BOLA2B(display_short)|uniprotkb:BOLA2A(gene name synonym)|uniprotkb:My016(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_001026997.1|refseq:NP_001034271.1|refseq:NP_001307508.1|refseq:XP_016855107.1|ensembl:ENSG00000169627(gene)|ensembl:ENSG00000183336(gene)|ensembl:ENST00000330978(transcript)|ensembl:ENST00000651894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9H3K6|reactome:R-HSA-8950505 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:5TcFdmQcwx5trexmXkWp9Arn5zE9606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01968-2 uniprotkb:P04083 intact:EBI-11749425|ensembl:ENSP00000349635 intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408655|imex:IM-26436-296 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 rigid:MtfzPWpuNDxupQLN5WsAD/4FwCU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75962-4 uniprotkb:Q9NYU2 intact:EBI-15915736 intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253 psi-mi:o75962-4(display_long)|uniprotkb:TRIO(gene name)|psi-mi:TRIO(display_short)|uniprotkb:PTPRF-interacting protein(gene name synonym) psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408725|imex:IM-26436-78 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-718519(isoform-parent)|uniprotkb:O75962-4(isoform-parent) refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032 - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:BfQ8eXa3IeoCNq7xq8Caqq/KGeg9606 rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606 rigid:QD2TRK1P9+3R5YDLT1nwOBQZMmg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75962-4 uniprotkb:P84095 intact:EBI-15915736 intact:EBI-446579|uniprotkb:P35238|uniprotkb:Q8NI04|ensembl:ENSP00000339467|ensembl:ENSP00000380175|ensembl:ENSP00000380176|ensembl:ENSP00000436932 psi-mi:o75962-4(display_long)|uniprotkb:TRIO(gene name)|psi-mi:TRIO(display_short)|uniprotkb:PTPRF-interacting protein(gene name synonym) psi-mi:rhog_human(display_long)|uniprotkb:RHOG(gene name)|psi-mi:RHOG(display_short)|uniprotkb:ARHG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408725|imex:IM-26436-78 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-718519(isoform-parent)|uniprotkb:O75962-4(isoform-parent) refseq:NP_001656.2|refseq:XP_005252973.1|refseq:XP_016873208.1|ensembl:ENST00000396978(transcript)|ensembl:ENST00000396979(transcript)|ensembl:ENST00000533217(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|ensembl:ENSG00000177105(gene)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|ensembl:ENST00000351018(transcript)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR042734|mint:P84095|rcsb pdb:6UKA|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-5625970|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-9013408 - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:BfQ8eXa3IeoCNq7xq8Caqq/KGeg9606 rogid:9PItVl1k5j6JhIDqwqcov1E/N8w9606 rigid:QD2TRK1P9+3R5YDLT1nwOBQZMmg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75962-4 uniprotkb:Q16543 intact:EBI-15915736 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:o75962-4(display_long)|uniprotkb:TRIO(gene name)|psi-mi:TRIO(display_short)|uniprotkb:PTPRF-interacting protein(gene name synonym) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408725|imex:IM-26436-78 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-718519(isoform-parent)|uniprotkb:O75962-4(isoform-parent) refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:BfQ8eXa3IeoCNq7xq8Caqq/KGeg9606 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 rigid:QD2TRK1P9+3R5YDLT1nwOBQZMmg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94887-1 uniprotkb:P51571 intact:EBI-25408805 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 psi-mi:o948871(display_long)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:PLEKHC3(gene name synonym) psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408813|imex:IM-26436-298 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94887-1(isoform-parent) refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 rigid:cstiPTpA7f8k8+BNWD3kAvN3/mo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94887-1 uniprotkb:Q8N490 intact:EBI-25408805 intact:EBI-746368|uniprotkb:Q96A48|uniprotkb:Q9BU26|uniprotkb:Q9NSX4|uniprotkb:Q9ULN6|uniprotkb:Q9Y4T1|uniprotkb:A8K1F2|ensembl:ENSP00000273077 psi-mi:o948871(display_long)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:PLEKHC3(gene name synonym) psi-mi:pnkd_human(display_long)|uniprotkb:Paroxysmal nonkinesiogenic dyskinesia protein(gene name synonym)|uniprotkb:Myofibrillogenesis regulator 1(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 2(gene name synonym)|uniprotkb:PNKD(gene name)|psi-mi:PNKD(display_short)|uniprotkb:KIAA1184(gene name synonym)|uniprotkb:MR1(gene name synonym)|uniprotkb:TAHCCP2(gene name synonym)|uniprotkb:FKSG19(orf name)|uniprotkb:UNQ2491/PRO5778(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408813|imex:IM-26436-298 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94887-1(isoform-parent) refseq:NP_001070867.1|refseq:NP_056303.3|refseq:NP_072094.1|ensembl:ENST00000273077(transcript)|go:"GO:0004416"(hydroxyacylglutathione hydrolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0019243"(methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0050884"(neuromuscular process controlling posture)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR017782(Hydroxyacylglutathione hydrolase)|interpro:IPR032282|interpro:IPR035680|interpro:IPR036866|ensembl:ENSG00000127838(gene) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606 rogid:LKItPq0mJBGgqEeDl3LoJAeTAl09606 rigid:cstiPTpA7f8k8+BNWD3kAvN3/mo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94887-1 uniprotkb:P15498 intact:EBI-25408805 intact:EBI-625518|ensembl:ENSP00000472929|uniprotkb:Q15860|uniprotkb:B4DVK9|uniprotkb:M0QXX6 psi-mi:o948871(display_long)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:PLEKHC3(gene name synonym) psi-mi:vav_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short)|uniprotkb:VAV(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408813|imex:IM-26436-298 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94887-1(isoform-parent) go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0072593"(reactive oxygen species metabolic process)|ensembl:ENSG00000141968(gene)|ensembl:ENST00000602142(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031295"(T cell costimulation)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0140031"(phosphorylation-dependent protein binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:P15498|rcsb pdb:2CRH|rcsb pdb:2LCT|rcsb pdb:2MC1|rcsb pdb:2ROR|rcsb pdb:3BJI|rcsb pdb:3KY9|rcsb pdb:6NEW|rcsb pdb:6NF1|rcsb pdb:6NFA|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-389359|reactome:R-HSA-416482|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5218920|reactome:R-HSA-6811558|reactome:R-HSA-8980692|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9027284|reactome:R-HSA-912631|reactome:R-HSA-9664422|reactome:R-HSA-983695|reactome:R-HSA-9013404|refseq:NP_005419.2|refseq:NP_001245136.1|dip:DIP-1061N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606 rogid:bQbV6leh4WHm+d0VGVCMuZtR6pU9606 rigid:cstiPTpA7f8k8+BNWD3kAvN3/mo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94887-1 uniprotkb:Q9Y3T9 intact:EBI-25408805 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:o948871(display_long)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:PLEKHC3(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408813|imex:IM-26436-298 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94887-1(isoform-parent) refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 rigid:cstiPTpA7f8k8+BNWD3kAvN3/mo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94887-1 uniprotkb:P25685 intact:EBI-25408805 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:o948871(display_long)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:PLEKHC3(gene name synonym) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408813|imex:IM-26436-298 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94887-1(isoform-parent) dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 rigid:cstiPTpA7f8k8+BNWD3kAvN3/mo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6J4 uniprotkb:Q8N392 intact:EBI-1057190|uniprotkb:Q5T8I1|uniprotkb:Q6P6A8|uniprotkb:Q6ZNL5|uniprotkb:Q8IZ32|uniprotkb:Q8N868|uniprotkb:Q9H7M2|ensembl:ENSP00000274963 intact:EBI-372814|uniprotkb:E1P575|uniprotkb:Q58EZ3|uniprotkb:Q6P679|uniprotkb:Q6PJD7|uniprotkb:Q96S64|intact:EBI-28984395|ensembl:ENSP00000357131 psi-mi:fgd2_human(display_long)|uniprotkb:FGD2(gene name)|psi-mi:FGD2(display_short)|uniprotkb:ZFYVE4(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 4(gene name synonym) psi-mi:rhg18_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym)|uniprotkb:MacGAP(gene name synonym)|uniprotkb:ARHGAP18(gene name)|psi-mi:ARHGAP18(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408789|imex:IM-26436-240 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775829.2|ensembl:ENSG00000146192(gene)|ensembl:ENST00000274963(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037797|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_277050.2|ensembl:ENSP00000357131|ensembl:ENSG00000146376(gene)|ensembl:ENST00000368149(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:2000145"(regulation of cell motility) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jAx/1RNr9M1EoPP9w6wks8dRLaA9606 rogid:24F0Swg/Ye/UfWPt8fJcO+q0nkc9606 rigid:/QugPbVkpuWB2+ldO9PAI1cxmDs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6J4 uniprotkb:O14776 intact:EBI-1057190|uniprotkb:Q5T8I1|uniprotkb:Q6P6A8|uniprotkb:Q6ZNL5|uniprotkb:Q8IZ32|uniprotkb:Q8N868|uniprotkb:Q9H7M2|ensembl:ENSP00000274963 intact:EBI-473271|uniprotkb:Q2NKN2|uniprotkb:Q59EA1|ensembl:ENSP00000296702 psi-mi:fgd2_human(display_long)|uniprotkb:FGD2(gene name)|psi-mi:FGD2(display_short)|uniprotkb:ZFYVE4(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 4(gene name synonym) psi-mi:tcrg1_human(display_long)|uniprotkb:TATA box-binding protein-associated factor 2S(gene name synonym)|uniprotkb:Transcription factor CA150(gene name synonym)|uniprotkb:TCERG1(gene name)|psi-mi:TCERG1(display_short)|uniprotkb:CA150(gene name synonym)|uniprotkb:TAF2S(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408789|imex:IM-26436-240 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775829.2|ensembl:ENSG00000146192(gene)|ensembl:ENST00000274963(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037797|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_001035095.1|refseq:NP_006697.2|dip:DIP-32504N|ensembl:ENSG00000113649(gene)|ensembl:ENST00000296702(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003711"(transcription elongation regulator activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002713(FF)|interpro:IPR036020|interpro:IPR036517|mint:O14776|rcsb pdb:2DK7|rcsb pdb:2DOD|rcsb pdb:2DOE|rcsb pdb:2DOF|rcsb pdb:2E71|rcsb pdb:2KIQ|rcsb pdb:2KIS|rcsb pdb:2MW9|rcsb pdb:2MWA|rcsb pdb:2MWB|rcsb pdb:2MWD|rcsb pdb:2MWE|rcsb pdb:2MWF|rcsb pdb:2N4R|rcsb pdb:2N4S|rcsb pdb:2N4T|rcsb pdb:2N4U|rcsb pdb:2N4V|rcsb pdb:2N4W|rcsb pdb:2NNT|rcsb pdb:3HFH|rcsb pdb:3Q1I|rcsb pdb:4FQG|rcsb pdb:7ABF|rcsb pdb:7ABG - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jAx/1RNr9M1EoPP9w6wks8dRLaA9606 rogid:KDFTOtTUWHzQ9yzRj7BbhFTQXiM9606 rigid:/QugPbVkpuWB2+ldO9PAI1cxmDs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6J4 uniprotkb:Q99959 intact:EBI-1057190|uniprotkb:Q5T8I1|uniprotkb:Q6P6A8|uniprotkb:Q6ZNL5|uniprotkb:Q8IZ32|uniprotkb:Q8N868|uniprotkb:Q9H7M2|ensembl:ENSP00000274963 intact:EBI-702235|intact:EBI-2692870|uniprotkb:D3DUW9|uniprotkb:Q99960|uniprotkb:Q4VC01|uniprotkb:B8QFA1|uniprotkb:B8QGS6|uniprotkb:B8QGS7|uniprotkb:A0AV37|ensembl:ENSP00000070846 psi-mi:fgd2_human(display_long)|uniprotkb:FGD2(gene name)|psi-mi:FGD2(display_short)|uniprotkb:ZFYVE4(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 4(gene name synonym) psi-mi:pkp2_human(display_long)|uniprotkb:PKP2(gene name)|psi-mi:PKP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408789|imex:IM-26436-240 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775829.2|ensembl:ENSG00000146192(gene)|ensembl:ENST00000274963(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037797|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_004563.2|refseq:NP_001005242.2|ensembl:ENSG00000057294(gene)|ensembl:ENST00000070846(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002159"(desmosome assembly)|go:"GO:0002934"(desmosome organization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007507"(heart development)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:Q99959|rcsb pdb:3TT9|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jAx/1RNr9M1EoPP9w6wks8dRLaA9606 rogid:kwGWMlk4SDz0xARlBMD1dY9fehQ9606 rigid:/QugPbVkpuWB2+ldO9PAI1cxmDs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6J4 uniprotkb:P82673 intact:EBI-1057190|uniprotkb:Q5T8I1|uniprotkb:Q6P6A8|uniprotkb:Q6ZNL5|uniprotkb:Q8IZ32|uniprotkb:Q8N868|uniprotkb:Q9H7M2|ensembl:ENSP00000274963 intact:EBI-2513649|ensembl:ENSP00000081029|uniprotkb:Q6P4C6|uniprotkb:Q7L1M6|uniprotkb:Q9HC14|uniprotkb:Q96AI0|uniprotkb:Q32LZ1|uniprotkb:Q9H044|uniprotkb:Q9P1R5|uniprotkb:Q8NBP4 psi-mi:fgd2_human(display_long)|uniprotkb:FGD2(gene name)|psi-mi:FGD2(display_short)|uniprotkb:ZFYVE4(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 4(gene name synonym) psi-mi:rt35_human(display_long)|uniprotkb:MRPS35(gene name)|psi-mi:MRPS35(display_short)|uniprotkb:MRPS28(gene name synonym)|uniprotkb:28S ribosomal protein S28, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS35(gene name synonym)|uniprotkb:HDCMD11P(orf name)|uniprotkb:MDS023(orf name)|uniprotkb:PSEC0213(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408789|imex:IM-26436-240 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775829.2|ensembl:ENSG00000146192(gene)|ensembl:ENST00000274963(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037797|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 ensembl:ENSG00000061794(gene)|ensembl:ENST00000081029(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR019349|interpro:IPR039848|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001177793.1|refseq:NP_068593.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jAx/1RNr9M1EoPP9w6wks8dRLaA9606 rogid:L7fhBRRkth1ePVbRtuVTvC5zcR09606 rigid:/QugPbVkpuWB2+ldO9PAI1cxmDs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6J4 uniprotkb:Q8WUH6 intact:EBI-1057190|uniprotkb:Q5T8I1|uniprotkb:Q6P6A8|uniprotkb:Q6ZNL5|uniprotkb:Q8IZ32|uniprotkb:Q8N868|uniprotkb:Q9H7M2|ensembl:ENSP00000274963 intact:EBI-1042811|uniprotkb:B3KMN9|ensembl:ENSP00000280756|ensembl:ENSP00000446537|ensembl:ENSP00000446717|ensembl:ENSP00000449106|ensembl:ENSP00000449785|ensembl:ENSP00000450350 psi-mi:fgd2_human(display_long)|uniprotkb:FGD2(gene name)|psi-mi:FGD2(display_short)|uniprotkb:ZFYVE4(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 4(gene name synonym) psi-mi:tm263_human(display_long)|uniprotkb:TMEM263(gene name)|psi-mi:TMEM263(display_short)|uniprotkb:C12orf23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408789|imex:IM-26436-240 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775829.2|ensembl:ENSG00000146192(gene)|ensembl:ENST00000274963(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037797|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_001306590.1|refseq:NP_001306591.1|refseq:NP_001306592.1|refseq:NP_001306593.1|refseq:NP_001306595.1|refseq:NP_689474.1|ensembl:ENSG00000151135(gene)|ensembl:ENST00000280756(transcript)|ensembl:ENST00000547081(transcript)|ensembl:ENST00000547242(transcript)|ensembl:ENST00000548125(transcript)|ensembl:ENST00000550344(transcript)|ensembl:ENST00000551813(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028153 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jAx/1RNr9M1EoPP9w6wks8dRLaA9606 rogid:7ndvPlnfctdWgCYMvx/yNZ8jyQE9606 rigid:/QugPbVkpuWB2+ldO9PAI1cxmDs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:Q96DI7 intact:EBI-25408737 intact:EBI-538492|uniprotkb:O75938|uniprotkb:O95320|uniprotkb:B4DQJ1|ensembl:ENSP00000263694 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:snr40_human(display_long)|uniprotkb:Prp8-binding protein(gene name synonym)|uniprotkb:U5 snRNP-specific 40 kDa protein(gene name synonym)|uniprotkb:38 kDa-splicing factor(gene name synonym)|uniprotkb:SNRNP40(gene name)|psi-mi:SNRNP40(display_short)|uniprotkb:PRP8BP(gene name synonym)|uniprotkb:SFP38(gene name synonym)|uniprotkb:WDR57(gene name synonym)|uniprotkb:WD repeat-containing protein 57(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) refseq:NP_004805.2|ensembl:ENSG00000060688(gene)|ensembl:ENST00000263694(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q96DI7|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:AfLoHYSy0MlW+OqHyEULLcpwQhQ9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:P51665 intact:EBI-25408737 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:Q8NEF9 intact:EBI-25408737 intact:EBI-2824681|uniprotkb:Q5QFI2|uniprotkb:Q96AH4|uniprotkb:Q96DK2|ensembl:ENSP00000341324 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:srfb1_human(display_long)|uniprotkb:SRFBP1(gene name)|psi-mi:SRFBP1(display_short)|uniprotkb:SRF-dependent transcription regulation-associated protein(gene name synonym)|uniprotkb:p49/STRAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) ensembl:ENSG00000151304(gene)|ensembl:ENST00000339397(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR015158(Bud-site selection protein, BUD22)|interpro:IPR037393|refseq:NP_689759.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:MQv9j4+l9h+7z05X/bRJAompesc9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:P08579 intact:EBI-25408737 intact:EBI-1053651|uniprotkb:Q9UJD4|uniprotkb:B2R7J3|uniprotkb:D3DW21|ensembl:ENSP00000246071|ensembl:ENSP00000367178 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:ru2b_human(display_long)|uniprotkb:SNRPB2(gene name)|psi-mi:SNRPB2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) refseq:NP_003083.1|refseq:NP_937863.1|ensembl:ENSG00000125870(gene)|ensembl:ENST00000246071(transcript)|ensembl:ENST00000377943(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070990"(snRNP binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034562|interpro:IPR034564|interpro:IPR035979|mint:P08579|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:AzDL3wfFG4HmOfTs8NJL6bWjgrc9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:Q9NW64 intact:EBI-25408737 intact:EBI-2602260|uniprotkb:A6NDM5|uniprotkb:O95607|uniprotkb:B4DLI9|ensembl:ENSP00000199814 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:rbm22_human(display_long)|uniprotkb:RBM22(gene name)|psi-mi:RBM22(display_short)|uniprotkb:ZC3H16(gene name synonym)|uniprotkb:RNA-binding motif protein 22(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 16(gene name synonym)|uniprotkb:199G4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) refseq:NP_060517.1|go:"GO:0035690"|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|rcsb pdb:2YTC|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|ensembl:ENST00000199814(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000086589(gene)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:PjcPER8I/RBxwu3oACO1LHxzKAM9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:Q86U42 intact:EBI-25408737 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:Q9UMY1 intact:EBI-25408737 intact:EBI-2862609|uniprotkb:Q9Y3U7|uniprotkb:Q5T297|ensembl:ENSP00000405674 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:nol7_human(display_long)|uniprotkb:NOL7(gene name)|psi-mi:NOL7(display_short)|uniprotkb:C6orf90(gene name synonym)|uniprotkb:NOP27(gene name synonym)|uniprotkb:Nucleolar protein of 27 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) refseq:NP_057251.2|refseq:NP_001304653.1|ensembl:ENSG00000225921(gene)|ensembl:ENST00000451315(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|interpro:IPR012579(NUC129)|interpro:IPR039626|mint:Q9UMY1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:4I1C2wd0qGg9CWZDodm/Bp+tptA9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:Q9UBC2 intact:EBI-25408737 intact:EBI-2556746|intact:EBI-28972990|ensembl:ENSP00000248070|uniprotkb:B4DKA3|uniprotkb:A2RRF3|uniprotkb:A5PL29 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:ep15r_human(display_long)|uniprotkb:EPS15R(gene name synonym)|uniprotkb:Eps15-related protein(gene name synonym)|uniprotkb:EPS15L1(gene name)|psi-mi:EPS15L1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) refseq:NP_067058.1|ensembl:ENSP00000248070|ensembl:ENST00000455140|ensembl:ENSP00000393313|ensembl:ENST00000535753|ensembl:ENSP00000440103|ensembl:ENST00000597937|ensembl:ENSP00000472267|ensembl:ENST00000602022|ensembl:ENSP00000471981|ensembl:ENSG00000127527(gene)|ensembl:ENST00000248070(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0045296"(cadherin binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBC2|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0030132"(clathrin coat of coated pit)|refseq:NP_001245303.1|refseq:NP_001245304.1|refseq:NP_001245305.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:6Bsao5czetxRxIiy3O/rZox4U+Y9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6H8W8 uniprotkb:P42566 intact:EBI-25408737 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:a6h8w8_human(display_long)|uniprotkb:ITSN2(gene name)|psi-mi:ITSN2(display_short) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408765|imex:IM-26436-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006897"(endocytosis)|refseq:NP_006268.2|refseq:NP_062541.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR035892|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR027029|interpro:IPR035737|interpro:IPR035738|interpro:IPR035739|interpro:IPR035740|interpro:IPR035741|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR036028|interpro:IPR001452(Src homology-3) refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jLq2Gq4CsGrN91FCSXlXcb9v00w9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rigid:2j1EEbq/l1pMqWa+85mMUwr4pWA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6B7-1 uniprotkb:Q8IW93 intact:EBI-25399647|ensembl:ENSP00000347198 intact:EBI-7799822|ensembl:ENSP00000270747|intact:MINT-6504085|uniprotkb:Q8N244|uniprotkb:Q6PJQ4|uniprotkb:Q5TEV2|uniprotkb:A6NJ04 psi-mi:q7z6b7-1(display_long)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym) psi-mi:arhgj_human(display_long)|uniprotkb:Ephexin-2(gene name synonym)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408829|imex:IM-26436-300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|intact:EBI-2481729(isoform-parent) refseq:XP_011539008.1|ensembl:ENSG00000142632(gene)|ensembl:ENST00000270747(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042060"(wound healing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR036028|mint:Q8IW93|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_694945.2 - - comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rigid:P3Tu1TxWnFIPqlcmqPS5TnuNakM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6B7-1 uniprotkb:O75044 intact:EBI-25399647|ensembl:ENSP00000347198 intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3 psi-mi:q7z6b7-1(display_long)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym) psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408829|imex:IM-26436-300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|intact:EBI-2481729(isoform-parent) refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rogid:/0NBTrPy/51L4LGytNP/80OifEE9606 rigid:P3Tu1TxWnFIPqlcmqPS5TnuNakM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6B7-1 uniprotkb:Q96B97 intact:EBI-25399647|ensembl:ENSP00000347198 intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921 psi-mi:q7z6b7-1(display_long)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym) psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408829|imex:IM-26436-300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|intact:EBI-2481729(isoform-parent) refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606 rigid:P3Tu1TxWnFIPqlcmqPS5TnuNakM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6B7-1 uniprotkb:Q9Y6N7 intact:EBI-25399647|ensembl:ENSP00000347198 intact:EBI-399762|uniprotkb:Q7Z300|uniprotkb:Q9BUS7|uniprotkb:D3DU36|uniprotkb:B2RXI1|uniprotkb:E9PD49|uniprotkb:Q1RMC7|ensembl:ENSP00000420321 psi-mi:q7z6b7-1(display_long)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym) psi-mi:robo1_human(display_long)|uniprotkb:ROBO1(gene name)|psi-mi:ROBO1(display_short)|uniprotkb:DUTT1(gene name synonym)|uniprotkb:H-Robo-1(gene name synonym)|uniprotkb:Deleted in U twenty twenty(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408829|imex:IM-26436-300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|intact:EBI-2481729(isoform-parent) refseq:NP_001139317.1|refseq:NP_002932.1|refseq:NP_598334.2|ensembl:ENSP00000420321|ensembl:ENST00000467549|ensembl:ENSP00000417992|ensembl:ENST00000495273|ensembl:ENSP00000420637|refseq:XP_006713340.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032986|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2EO9|rcsb pdb:2V9Q|rcsb pdb:2V9R|rcsb pdb:2V9T|rcsb pdb:3WIH|rcsb pdb:4HLJ|rcsb pdb:5O5G|rcsb pdb:5O5I|rcsb pdb:5OPE|rcsb pdb:6A77|rcsb pdb:6A78|ensembl:ENSG00000169855(gene)|ensembl:ENST00000464233(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009986"(cell surface)|refseq:XP_016862472.1|dip:DIP-33034N|rcsb pdb:6A79|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-8985801|reactome:R-HSA-9010553 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rogid:LLHEVlylzhWB/zr77pQrNizgVsg9606 rigid:P3Tu1TxWnFIPqlcmqPS5TnuNakM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6B7-1 uniprotkb:Q70E73 intact:EBI-25399647|ensembl:ENSP00000347198 intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543 psi-mi:q7z6b7-1(display_long)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym) psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408829|imex:IM-26436-300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|intact:EBI-2481729(isoform-parent) refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606 rigid:P3Tu1TxWnFIPqlcmqPS5TnuNakM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6B7-1 uniprotkb:P30414 intact:EBI-25399647|ensembl:ENSP00000347198 intact:EBI-1642562|ensembl:ENSP00000232978 psi-mi:q7z6b7-1(display_long)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym) psi-mi:nktr_human(display_long)|uniprotkb:NKTR(gene name)|psi-mi:NKTR(display_short)|uniprotkb:Natural-killer cells cyclophilin-related protein(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase NKTR(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408829|imex:IM-26436-300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|intact:EBI-2481729(isoform-parent) refseq:NP_005376.2|ensembl:ENSG00000114857(gene)|ensembl:ENST00000232978(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P30414|rcsb pdb:2HE9 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rogid:+klgWL+1/tJS3kNQb6HDqh7n4FY9606 rigid:P3Tu1TxWnFIPqlcmqPS5TnuNakM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6B7-1 uniprotkb:Q07960 intact:EBI-25399647|ensembl:ENSP00000347198 intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491 psi-mi:q7z6b7-1(display_long)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym) psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408829|imex:IM-26436-300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|intact:EBI-2481729(isoform-parent) refseq:NP_004299.1|refseq:XP_011518397.1|dip:DIP-6081N|ensembl:ENSG00000175220(gene)|ensembl:ENST00000311956(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rogid:ceA3oLsnddhLiSbylS89P64mYBo9606 rigid:P3Tu1TxWnFIPqlcmqPS5TnuNakM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BZN6 uniprotkb:Q05048 intact:EBI-12602119|uniprotkb:F1AHI9 intact:EBI-1789619|uniprotkb:Q5QPD8|ensembl:ENSP00000217109 psi-mi:doc10_mouse(display_long)|uniprotkb:Dock10(gene name)|psi-mi:Dock10(display_short)|uniprotkb:Kiaa0694(gene name synonym)|uniprotkb:Ziz3(gene name synonym)|uniprotkb:Zizimin-3(gene name synonym) psi-mi:cstf1_human(display_long)|uniprotkb:CSTF1(gene name)|psi-mi:CSTF1(display_short)|uniprotkb:CF-1 50 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 50 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408912|imex:IM-26436-154 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001782"(B cell homeostasis)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0060997"(dendritic spine morphogenesis)|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|reactome:R-MMU-983231|interpro:IPR035892|interpro:IPR037809|refseq:NP_001272856.1|refseq:NP_780500.2|interpro:IPR027007|interpro:IPR027357|interpro:IPR026791|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043162 refseq:XP_011526902.1|refseq:NP_001028693.1|refseq:NP_001028694.1|refseq:NP_001315.1|ensembl:ENSG00000101138(gene)|ensembl:ENST00000217109(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005848"(mRNA cleavage stimulating factor complex)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR032028|interpro:IPR036322|interpro:IPR038184|interpro:IPR044633|mint:Q05048|rcsb pdb:6B3X|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:as2OJvFaS/MKcK+RbYGJLbWfcxE10090 rogid:p1WA38/ygDg6E9lsofH6JH8wU7k9606 rigid:uTRpws8F+WNAqHrK766Yc/RyHQ0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8BZN6 uniprotkb:O75962 intact:EBI-12602119|uniprotkb:F1AHI9 intact:EBI-718519|uniprotkb:Q13458|uniprotkb:Q59EQ7|uniprotkb:Q6PJC9|uniprotkb:Q6ZN05|uniprotkb:Q8IWK8|uniprotkb:D3DTD1|ensembl:ENSP00000339299 psi-mi:doc10_mouse(display_long)|uniprotkb:Dock10(gene name)|psi-mi:Dock10(display_short)|uniprotkb:Kiaa0694(gene name synonym)|uniprotkb:Ziz3(gene name synonym)|uniprotkb:Zizimin-3(gene name synonym) psi-mi:trio_human(display_long)|uniprotkb:PTPRF-interacting protein(gene name synonym)|uniprotkb:TRIO(gene name)|psi-mi:TRIO(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408912|imex:IM-26436-154 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001782"(B cell homeostasis)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0060997"(dendritic spine morphogenesis)|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|reactome:R-MMU-983231|interpro:IPR035892|interpro:IPR037809|refseq:NP_001272856.1|refseq:NP_780500.2|interpro:IPR027007|interpro:IPR027357|interpro:IPR026791|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043162 refseq:NP_009049.2|refseq:XP_011512412.1|ensembl:ENSG00000038382(gene)|ensembl:ENST00000344204(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0042995"(cell projection)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036179|interpro:IPR036865|mint:O75962|rcsb pdb:1NTY|rcsb pdb:2NZ8|rcsb pdb:6D8Z|reactome:R-HSA-193648|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418885|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|interpro:IPR008271(Serine/threonine protein kinase, active site)|dip:DIP-37578N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:as2OJvFaS/MKcK+RbYGJLbWfcxE10090 rogid:d01ioB7N6ccwAkeeoGpAa9GHZN89606 rigid:uTRpws8F+WNAqHrK766Yc/RyHQ0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N1W1-6 uniprotkb:Q9UQE7 intact:EBI-25399694|ensembl:ENSP00000411459|ensembl:ENSP00000441913 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:q8n1w1-6(display_long)|uniprotkb:ARHGEF28(gene name)|psi-mi:ARHGEF28(display_short)|uniprotkb:KIAA1998(gene name synonym)|uniprotkb:RGNEF(gene name synonym)|uniprotkb:190 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Rho guanine nucleotide exchange factor(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408896|imex:IM-26436-304 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9050764(isoform-parent)|ensembl:ENSG00000214944(gene)|ensembl:ENST00000437974(transcript)|ensembl:ENST00000545377(transcript) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:E6MBNGfnhdyjJIpeFCWaFuVXsq89606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rigid:5HYydLPAnNcXxUO2O24kq6Hwm/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N1W1-6 uniprotkb:Q9Y265 intact:EBI-25399694|ensembl:ENSP00000411459|ensembl:ENSP00000441913 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:q8n1w1-6(display_long)|uniprotkb:ARHGEF28(gene name)|psi-mi:ARHGEF28(display_short)|uniprotkb:KIAA1998(gene name synonym)|uniprotkb:RGNEF(gene name synonym)|uniprotkb:190 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Rho guanine nucleotide exchange factor(gene name synonym) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408896|imex:IM-26436-304 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9050764(isoform-parent)|ensembl:ENSG00000214944(gene)|ensembl:ENST00000437974(transcript)|ensembl:ENST00000545377(transcript) refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:E6MBNGfnhdyjJIpeFCWaFuVXsq89606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 rigid:5HYydLPAnNcXxUO2O24kq6Hwm/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N1W1-6 uniprotkb:O43307 intact:EBI-25399694|ensembl:ENSP00000411459|ensembl:ENSP00000441913 intact:EBI-3447299|uniprotkb:Q5JSL6|uniprotkb:A8K1S8|uniprotkb:B4DHC7|intact:EBI-28976942|ensembl:ENSP00000253401|ensembl:ENSP00000500829|uniprotkb:F8W7P8 psi-mi:q8n1w1-6(display_long)|uniprotkb:ARHGEF28(gene name)|psi-mi:ARHGEF28(display_short)|uniprotkb:KIAA1998(gene name synonym)|uniprotkb:RGNEF(gene name synonym)|uniprotkb:190 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Rho guanine nucleotide exchange factor(gene name synonym) psi-mi:arhg9_human(display_long)|uniprotkb:ARHGEF9(gene name)|psi-mi:ARHGEF9(display_short)|uniprotkb:KIAA0424(gene name synonym)|uniprotkb:Collybistin(gene name synonym)|uniprotkb:PEM-2 homolog(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 9(gene name synonym)|uniprotkb:ARHDH9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408896|imex:IM-26436-304 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9050764(isoform-parent)|ensembl:ENSG00000214944(gene)|ensembl:ENST00000437974(transcript)|ensembl:ENST00000545377(transcript) ensembl:ENSP00000253401|ensembl:ENST00000623517|ensembl:ENSP00000485369|ensembl:ENST00000624843|ensembl:ENSP00000485626|ensembl:ENSP00000500829|refseq:NP_001166950.1|refseq:NP_001166951.1|refseq:NP_056000.1|ensembl:ENSG00000131089(gene)|ensembl:ENST00000253401(transcript)|ensembl:ENST00000671907(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035728|interpro:IPR035899|interpro:IPR036028|rcsb pdb:2YSQ|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-977443|refseq:XP_016884855.1|refseq:XP_016884862.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:E6MBNGfnhdyjJIpeFCWaFuVXsq89606 rogid:fNeHhwbyPWGv+2Iak2k7AE/gDd49606 rigid:5HYydLPAnNcXxUO2O24kq6Hwm/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N1W1-6 uniprotkb:Q6ZSZ5 intact:EBI-25399694|ensembl:ENSP00000411459|ensembl:ENSP00000441913 intact:EBI-2825649|uniprotkb:Q6DD92|uniprotkb:O60274|uniprotkb:A8MV62|uniprotkb:B5ME81|intact:EBI-28968180|uniprotkb:I3L1I5|ensembl:ENSP00000499655 psi-mi:q8n1w1-6(display_long)|uniprotkb:ARHGEF28(gene name)|psi-mi:ARHGEF28(display_short)|uniprotkb:KIAA1998(gene name synonym)|uniprotkb:RGNEF(gene name synonym)|uniprotkb:190 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Rho guanine nucleotide exchange factor(gene name synonym) psi-mi:arhgi_human(display_long)|uniprotkb:ARHGEF18(gene name)|psi-mi:ARHGEF18(display_short)|uniprotkb:KIAA0521(gene name synonym)|uniprotkb:114 kDa Rho-specific guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Septin-associated RhoGEF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408896|imex:IM-26436-304 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9050764(isoform-parent)|ensembl:ENSG00000214944(gene)|ensembl:ENST00000437974(transcript)|ensembl:ENST00000545377(transcript) ensembl:ENST00000594665|ensembl:ENSP00000470729|ensembl:ENST00000617428|ensembl:ENSP00000482647|ensembl:ENSP00000499655|refseq:XP_011526142.1|refseq:XP_006722768.1|refseq:XP_006722769.1|refseq:XP_011526140.1|refseq:XP_011526141.1|refseq:XP_006722771.1|refseq:NP_001124427.1|refseq:NP_056133.2|ensembl:ENSG00000104880(gene)|ensembl:ENST00000668164(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045177"(apical part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR035899|interpro:IPR037744|interpro:IPR041020|reactome:R-HSA-193648|reactome:R-HSA-2173791|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:E6MBNGfnhdyjJIpeFCWaFuVXsq89606 rogid:smLgrs8rq5LPpMsYLt3ynoL45Iw9606 rigid:5HYydLPAnNcXxUO2O24kq6Hwm/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N1W1-6 uniprotkb:Q12802 intact:EBI-25399694|ensembl:ENSP00000411459|ensembl:ENSP00000441913 intact:EBI-1373806|uniprotkb:Q14572|uniprotkb:Q59FP6|uniprotkb:Q86W90|uniprotkb:Q8WXQ6|uniprotkb:Q96JP6|uniprotkb:Q96P79|uniprotkb:Q9Y5T0|uniprotkb:Q9Y5T6|intact:EBI-28978093|ensembl:ENSP00000378026 psi-mi:q8n1w1-6(display_long)|uniprotkb:ARHGEF28(gene name)|psi-mi:ARHGEF28(display_short)|uniprotkb:KIAA1998(gene name synonym)|uniprotkb:RGNEF(gene name synonym)|uniprotkb:190 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Rho guanine nucleotide exchange factor(gene name synonym) psi-mi:akp13_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408896|imex:IM-26436-304 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9050764(isoform-parent)|ensembl:ENSG00000214944(gene)|ensembl:ENST00000437974(transcript)|ensembl:ENST00000545377(transcript) refseq:NP_006729.4|refseq:NP_009131.2|ensembl:ENST00000361243|ensembl:ENSP00000354718|ensembl:ENSP00000378026|ensembl:ENST00000560302|ensembl:ENSP00000453634|refseq:NP_001257475.1|dip:DIP-180N|ensembl:ENSG00000170776(gene)|ensembl:ENST00000394518(transcript)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051168"(nuclear export)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060297"(regulation of sarcomere organization)|go:"GO:0060348"(bone development)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018459|interpro:IPR028852|interpro:IPR035899|interpro:IPR041020|mint:Q12802|rcsb pdb:2DRN|rcsb pdb:2LG1|rcsb pdb:4D0N|rcsb pdb:4D0O|rcsb pdb:6BCA|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:E6MBNGfnhdyjJIpeFCWaFuVXsq89606 rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606 rigid:5HYydLPAnNcXxUO2O24kq6Hwm/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6KAU7-1 uniprotkb:P31944 intact:EBI-25408849 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:q6kau71(display_long)|uniprotkb:Plekhg2(gene name)|psi-mi:Plekhg2(display_short) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408855|imex:IM-26436-196 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6KAU7-1(isoform-parent) interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:dXGGTTI+0TT3w+smQhAUhtgJatU10090 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 rigid:NIEHu7nJcPjnHJROQwbkkim87+0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6KAU7-1 uniprotkb:P57088 intact:EBI-25408849 intact:EBI-1048629|uniprotkb:Q9H953|uniprotkb:B3KSS8|ensembl:ENSP00000422473|ensembl:ENSP00000427006|ensembl:ENSP00000441455 psi-mi:q6kau71(display_long)|uniprotkb:Plekhg2(gene name)|psi-mi:Plekhg2(display_short) psi-mi:tmm33_human(display_long)|uniprotkb:Protein DB83(gene name synonym)|uniprotkb:TMEM33(gene name)|psi-mi:TMEM33(display_short)|uniprotkb:DB83(gene name synonym)|uniprotkb:SHINC-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408855|imex:IM-26436-196 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6KAU7-1(isoform-parent) refseq:NP_060596.2|refseq:XP_005248173.1|refseq:XP_005248174.1|ensembl:ENSG00000109133(gene)|ensembl:ENST00000325094(transcript)|ensembl:ENST00000504986(transcript)|ensembl:ENST00000513702(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061024"(membrane organization)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR005344(Protein of unknown function UPF0121)|mint:P57088 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:dXGGTTI+0TT3w+smQhAUhtgJatU10090 rogid:FGc4/gpnYoRtlDJMxQWh5hXe5Ko9606 rigid:NIEHu7nJcPjnHJROQwbkkim87+0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6KAU7-1 uniprotkb:O15269 intact:EBI-25408849 intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554 psi-mi:q6kau71(display_long)|uniprotkb:Plekhg2(gene name)|psi-mi:Plekhg2(display_short) psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408855|imex:IM-26436-196 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6KAU7-1(isoform-parent) refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:dXGGTTI+0TT3w+smQhAUhtgJatU10090 rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606 rigid:NIEHu7nJcPjnHJROQwbkkim87+0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6KAU7-1 uniprotkb:P53985 intact:EBI-25408849 intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|uniprotkb:Q49A45|ensembl:ENSP00000416167|ensembl:ENSP00000441065|ensembl:ENSP00000485688|ensembl:ENSP00000358640|ensembl:ENSP00000397106|ensembl:ENSP00000399104|ensembl:ENSP00000486000|ensembl:ENSP00000505879 psi-mi:q6kau71(display_long)|uniprotkb:Plekhg2(gene name)|psi-mi:Plekhg2(display_short) psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408855|imex:IM-26436-196 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6KAU7-1(isoform-parent) refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|ensembl:ENSG00000155380(gene)|ensembl:ENSG00000281917(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032094"(response to food)|ensembl:ENST00000369626(transcript)|ensembl:ENST00000429288(transcript)|ensembl:ENST00000443580(transcript)|ensembl:ENST00000458229(transcript)|ensembl:ENST00000538576(transcript)|ensembl:ENST00000628110(transcript)|ensembl:ENST00000630362(transcript)|ensembl:ENST00000679803(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015130"(mevalonate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0015728"(mevalonate transport)|go:"GO:0016020"(membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051780"(behavioral response to nutrient)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|mint:P53985|go:"GO:1905039"(carboxylic acid transmembrane transport)|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:dXGGTTI+0TT3w+smQhAUhtgJatU10090 rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606 rigid:NIEHu7nJcPjnHJROQwbkkim87+0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6KAU7-1 uniprotkb:O94906 intact:EBI-25408849 intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|ensembl:ENSP00000266079|uniprotkb:B2RAR5|uniprotkb:B3KMC6 psi-mi:q6kau71(display_long)|uniprotkb:Plekhg2(gene name)|psi-mi:Plekhg2(display_short) psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408855|imex:IM-26436-196 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6KAU7-1(isoform-parent) ensembl:ENSG00000101161(gene)|ensembl:ENST00000266079(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:dXGGTTI+0TT3w+smQhAUhtgJatU10090 rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606 rigid:NIEHu7nJcPjnHJROQwbkkim87+0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6KAU7-1 uniprotkb:Q9BRT2 intact:EBI-25408849 intact:EBI-1054584|uniprotkb:B2R4I0|ensembl:ENSP00000476140 psi-mi:q6kau71(display_long)|uniprotkb:Plekhg2(gene name)|psi-mi:Plekhg2(display_short) psi-mi:uqcc2_human(display_long)|uniprotkb:UQCC2(gene name)|psi-mi:UQCC2(display_short)|uniprotkb:Breast cancer-associated protein SGA-81M(gene name synonym)|uniprotkb:C6orf125(gene name synonym)|uniprotkb:MNF1(gene name synonym)|uniprotkb:Mitochondrial nucleoid factor 1(gene name synonym)|uniprotkb:Mitochondrial protein M19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408855|imex:IM-26436-196 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6KAU7-1(isoform-parent) refseq:NP_115716.1|ensembl:ENSG00000137288(gene)|ensembl:ENST00000607484(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR037698 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:dXGGTTI+0TT3w+smQhAUhtgJatU10090 rogid:5bqVcfnTXOCOuCVCrEtzEaChT3Y9606 rigid:NIEHu7nJcPjnHJROQwbkkim87+0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A7KAX9-1 uniprotkb:P60468 intact:EBI-25408873|ensembl:ENSP00000310561 intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641 psi-mi:a7kax9-1(display_long)|uniprotkb:Brain-specific Rho GTPase-activating protein(gene name synonym)|uniprotkb:GAB-associated Cdc42/Rac GTPase-activating protein(gene name synonym)|uniprotkb:GC-GAP(gene name synonym)|uniprotkb:GTPase regulator interacting with TrkA(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 32(gene name synonym)|uniprotkb:Rho/Cdc42/Rac GTPase-activating protein RICS(gene name synonym)|uniprotkb:RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling(gene name synonym)|uniprotkb:p200RhoGAP(gene name synonym)|uniprotkb:p250GAP(gene name synonym)|uniprotkb:PX-RICS(isoform synonym)|uniprotkb:ARHGAP32(gene name)|psi-mi:ARHGAP32(display_short)|uniprotkb:GRIT(gene name synonym)|uniprotkb:KIAA0712(gene name synonym)|uniprotkb:RICS(gene name synonym) psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408884|imex:IM-26436-302 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134909(gene)|ensembl:ENST00000310343(transcript)|uniprotkb:A7KAX9-1(isoform-parent)|intact:EBI-308663(isoform-parent) refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:V51KfHcAYYMGvIsWaG5hNqZ49Yk9606 rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606 rigid:qTmwDUHJmKQGrPmNXvBW5ulC59g false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A7KAX9-1 uniprotkb:Q9NQX3 intact:EBI-25408873|ensembl:ENSP00000310561 intact:EBI-2371891|uniprotkb:Q9H4E9|uniprotkb:Q9P2G2|uniprotkb:Q96KU4|ensembl:ENSP00000312771 psi-mi:a7kax9-1(display_long)|uniprotkb:Brain-specific Rho GTPase-activating protein(gene name synonym)|uniprotkb:GAB-associated Cdc42/Rac GTPase-activating protein(gene name synonym)|uniprotkb:GC-GAP(gene name synonym)|uniprotkb:GTPase regulator interacting with TrkA(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 32(gene name synonym)|uniprotkb:Rho/Cdc42/Rac GTPase-activating protein RICS(gene name synonym)|uniprotkb:RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling(gene name synonym)|uniprotkb:p200RhoGAP(gene name synonym)|uniprotkb:p250GAP(gene name synonym)|uniprotkb:PX-RICS(isoform synonym)|uniprotkb:ARHGAP32(gene name)|psi-mi:ARHGAP32(display_short)|uniprotkb:GRIT(gene name synonym)|uniprotkb:KIAA0712(gene name synonym)|uniprotkb:RICS(gene name synonym) psi-mi:geph_human(display_long)|uniprotkb:GPHN(gene name)|psi-mi:GPHN(display_short)|uniprotkb:GPH(gene name synonym)|uniprotkb:KIAA1385(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408884|imex:IM-26436-302 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134909(gene)|ensembl:ENST00000310343(transcript)|uniprotkb:A7KAX9-1(isoform-parent)|intact:EBI-308663(isoform-parent) refseq:NP_001019389.1|refseq:NP_065857.1|dip:DIP-41076N|rcsb pdb:1JLJ|reactome:R-HSA-947581|interpro:IPR038987|ensembl:ENSG00000171723(gene)|ensembl:ENST00000315266(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0010038"(response to metal ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018315"(molybdenum incorporation into molybdenum-molybdopterin complex)|go:"GO:0030425"(dendrite)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0061598"(molybdopterin adenylyltransferase activity)|go:"GO:0061599"(molybdopterin molybdotransferase activity)|go:"GO:0072579"(glycine receptor clustering)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0099144"(anchored component of synaptic membrane)|go:"GO:0099572"(postsynaptic specialization)|go:"GO:0099634"(postsynaptic specialization membrane)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR008284(Molybdenum cofactor biosynthesis, conserved site)|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:V51KfHcAYYMGvIsWaG5hNqZ49Yk9606 rogid:iu4Nl7g9dOChbmYok/lo6kjW3pM9606 rigid:qTmwDUHJmKQGrPmNXvBW5ulC59g false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A7KAX9-1 uniprotkb:Q8N264 intact:EBI-25408873|ensembl:ENSP00000310561 intact:EBI-988764|ensembl:ENSP00000378611|uniprotkb:Q4KMG1|uniprotkb:Q6ZNV3|uniprotkb:Q86TI5|uniprotkb:Q86WE4|uniprotkb:Q9H0T6 psi-mi:a7kax9-1(display_long)|uniprotkb:Brain-specific Rho GTPase-activating protein(gene name synonym)|uniprotkb:GAB-associated Cdc42/Rac GTPase-activating protein(gene name synonym)|uniprotkb:GC-GAP(gene name synonym)|uniprotkb:GTPase regulator interacting with TrkA(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 32(gene name synonym)|uniprotkb:Rho/Cdc42/Rac GTPase-activating protein RICS(gene name synonym)|uniprotkb:RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling(gene name synonym)|uniprotkb:p200RhoGAP(gene name synonym)|uniprotkb:p250GAP(gene name synonym)|uniprotkb:PX-RICS(isoform synonym)|uniprotkb:ARHGAP32(gene name)|psi-mi:ARHGAP32(display_short)|uniprotkb:GRIT(gene name synonym)|uniprotkb:KIAA0712(gene name synonym)|uniprotkb:RICS(gene name synonym) psi-mi:rhg24_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408884|imex:IM-26436-302 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134909(gene)|ensembl:ENST00000310343(transcript)|uniprotkb:A7KAX9-1(isoform-parent)|intact:EBI-308663(isoform-parent) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0035021"(negative regulation of Rac protein signal transduction)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0042995"(cell projection)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_112595.2|refseq:NP_001020787.2|refseq:NP_001036134.1|refseq:XP_011530602.1|dip:DIP-35520N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:V51KfHcAYYMGvIsWaG5hNqZ49Yk9606 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rigid:qTmwDUHJmKQGrPmNXvBW5ulC59g false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P107-1 uniprotkb:Q8WXF1 intact:EBI-25408932 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:q9p1071(display_long)|uniprotkb:GMIP(gene name)|psi-mi:GMIP(display_short) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408937|imex:IM-26436-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P107-1(isoform-parent) refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Ewdy5WDD4tAafvZkjV4VJs9p+c89606 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 rigid:8WLWgADh+HtKK3dkKpMz/W7gUfY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P107-1 uniprotkb:P83916 intact:EBI-25408932 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:q9p1071(display_long)|uniprotkb:GMIP(gene name)|psi-mi:GMIP(display_short) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408937|imex:IM-26436-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P107-1(isoform-parent) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Ewdy5WDD4tAafvZkjV4VJs9p+c89606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:8WLWgADh+HtKK3dkKpMz/W7gUfY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P107-1 uniprotkb:Q15050 intact:EBI-25408932 intact:EBI-749186|uniprotkb:Q9BUX8|ensembl:ENSP00000322396 psi-mi:q9p1071(display_long)|uniprotkb:GMIP(gene name)|psi-mi:GMIP(display_short) psi-mi:rrs1_human(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:KIAA0112(gene name synonym)|uniprotkb:RRR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408937|imex:IM-26436-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P107-1(isoform-parent) refseq:NP_055984.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|mint:Q15050|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000179041(gene)|ensembl:ENST00000320270(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Ewdy5WDD4tAafvZkjV4VJs9p+c89606 rogid:0Nm9UoIGLBiqOGl0E2BA0S5EXIU9606 rigid:8WLWgADh+HtKK3dkKpMz/W7gUfY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P107-1 uniprotkb:Q8NFH5 intact:EBI-25408932 intact:EBI-9050429|uniprotkb:B4DP57|uniprotkb:B4DYB4|uniprotkb:Q4ZFZ9|uniprotkb:Q53S95|uniprotkb:Q8TDJ1|ensembl:ENSP00000295119 psi-mi:q9p1071(display_long)|uniprotkb:GMIP(gene name)|psi-mi:GMIP(display_short) psi-mi:nup35_human(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:NUP35(gene name)|psi-mi:NUP35(display_short)|uniprotkb:MP44(gene name synonym)|uniprotkb:NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Mitotic phosphoprotein 44(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408937|imex:IM-26436-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P107-1(isoform-parent) refseq:XP_006712317.1|refseq:XP_011508878.1|refseq:XP_011508879.1|refseq:NP_001274513.1|refseq:NP_612142.2|refseq:NP_001274514.1|dip:DIP-47308N|ensembl:ENSG00000163002(gene)|ensembl:ENST00000295119(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|mint:Q8NFH5|rcsb pdb:4LIR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Ewdy5WDD4tAafvZkjV4VJs9p+c89606 rogid:oFL2V05tM9dYT+fjUiqMLwxZYr89606 rigid:8WLWgADh+HtKK3dkKpMz/W7gUfY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P107-1 uniprotkb:P30533 intact:EBI-25408932 intact:EBI-715927|uniprotkb:Q2M310|uniprotkb:Q53HQ3|uniprotkb:Q53HS6|uniprotkb:D3DVR9|ensembl:ENSP00000497444 psi-mi:q9p1071(display_long)|uniprotkb:GMIP(gene name)|psi-mi:GMIP(display_short) psi-mi:amrp_human(display_long)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:LRPAP1(gene name)|psi-mi:LRPAP1(display_short)|uniprotkb:A2MRAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408937|imex:IM-26436-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P107-1(isoform-parent) refseq:NP_002328.1|ensembl:ENSG00000163956(gene)|ensembl:ENST00000650182(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900116"(extracellular negative regulation of signal transduction)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:P30533|rcsb pdb:1LRE|rcsb pdb:1NRE|rcsb pdb:1OP1|rcsb pdb:1OV2|rcsb pdb:2FCW|rcsb pdb:2FTU|rcsb pdb:2FYL|rcsb pdb:2P01|rcsb pdb:2P03|dip:DIP-39355N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Ewdy5WDD4tAafvZkjV4VJs9p+c89606 rogid:TIbL+P1GW4op4Qawa4lpg8iXUaQ9606 rigid:8WLWgADh+HtKK3dkKpMz/W7gUfY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P107-1 uniprotkb:O75955 intact:EBI-25408932 intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7 psi-mi:q9p1071(display_long)|uniprotkb:GMIP(gene name)|psi-mi:GMIP(display_short) psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408937|imex:IM-26436-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P107-1(isoform-parent) go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Ewdy5WDD4tAafvZkjV4VJs9p+c89606 rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606 rigid:8WLWgADh+HtKK3dkKpMz/W7gUfY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P107-1 uniprotkb:Q99848 intact:EBI-25408932 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:q9p1071(display_long)|uniprotkb:GMIP(gene name)|psi-mi:GMIP(display_short) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408937|imex:IM-26436-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P107-1(isoform-parent) refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Ewdy5WDD4tAafvZkjV4VJs9p+c89606 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 rigid:8WLWgADh+HtKK3dkKpMz/W7gUfY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96M96 uniprotkb:O43813 intact:EBI-4401039|uniprotkb:Q6ULS2|uniprotkb:Q8TCP6|ensembl:ENSP00000394487|ensembl:ENSP00000433666|ensembl:ENSP00000462623 intact:EBI-3046631|ensembl:ENSP00000233714|ensembl:ENSP00000388713|ensembl:ENSP00000393323|ensembl:ENSP00000393597|ensembl:ENSP00000397646 psi-mi:fgd4_human(display_long)|uniprotkb:FGD4(gene name)|psi-mi:FGD4(display_short)|uniprotkb:FRABP(gene name synonym)|uniprotkb:ZFYVE6(gene name synonym)|uniprotkb:Actin filament-binding protein frabin(gene name synonym)|uniprotkb:FGD1-related F-actin-binding protein(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 6(gene name synonym) psi-mi:lanc1_human(display_long)|uniprotkb:LANCL1(gene name)|psi-mi:LANCL1(display_short)|uniprotkb:GPR69A(gene name synonym)|uniprotkb:40 kDa erythrocyte membrane protein(gene name synonym)|uniprotkb:LanC-like protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408922|imex:IM-26436-80 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_640334.2|refseq:NP_001291409.1|refseq:XP_011518857.1|refseq:XP_011518858.1|refseq:NP_001317303.1|refseq:NP_001317302.1|ensembl:ENSG00000139132(gene)|ensembl:ENST00000427716(transcript)|ensembl:ENST00000525053(transcript)|ensembl:ENST00000583694(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037742|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|interpro:IPR017455(Zinc finger, FYVE-related) ensembl:ENSG00000115365(gene)|ensembl:ENST00000233714(transcript)|ensembl:ENST00000431941(transcript)|ensembl:ENST00000441020(transcript)|ensembl:ENST00000443314(transcript)|ensembl:ENST00000450366(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043295"(glutathione binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR020464|mint:O43813|rcsb pdb:3E6U|rcsb pdb:3E73|refseq:NP_001130046.1|refseq:NP_001130047.1|refseq:NP_006046.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:K4gzeBUhltm9N1SSPFdtgrmYsu89606 rogid:em3J/MvBGB1LZ0X1QFagwWBk5FQ9606 rigid:OZsjvkZx0T5ewzr08uuShu1AZHU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96M96 uniprotkb:Q8WXX5 intact:EBI-4401039|uniprotkb:Q6ULS2|uniprotkb:Q8TCP6|ensembl:ENSP00000394487|ensembl:ENSP00000433666|ensembl:ENSP00000462623 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:fgd4_human(display_long)|uniprotkb:FGD4(gene name)|psi-mi:FGD4(display_short)|uniprotkb:FRABP(gene name synonym)|uniprotkb:ZFYVE6(gene name synonym)|uniprotkb:Actin filament-binding protein frabin(gene name synonym)|uniprotkb:FGD1-related F-actin-binding protein(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 6(gene name synonym) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408922|imex:IM-26436-80 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_640334.2|refseq:NP_001291409.1|refseq:XP_011518857.1|refseq:XP_011518858.1|refseq:NP_001317303.1|refseq:NP_001317302.1|ensembl:ENSG00000139132(gene)|ensembl:ENST00000427716(transcript)|ensembl:ENST00000525053(transcript)|ensembl:ENST00000583694(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037742|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|interpro:IPR017455(Zinc finger, FYVE-related) refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:K4gzeBUhltm9N1SSPFdtgrmYsu89606 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 rigid:OZsjvkZx0T5ewzr08uuShu1AZHU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15013-5 uniprotkb:Q9Y2Z0 intact:EBI-25409011 intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6 psi-mi:o150135(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409018|imex:IM-26436-156 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O15013-5(isoform-parent) reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:4nooxkCzYKDyfRBmHGoaBa26bbE9606 rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606 rigid:Q9IrAHfI25KgjTYo839bCiGl8j4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15013-5 uniprotkb:P05109 intact:EBI-25409011 intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722 psi-mi:o150135(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409018|imex:IM-26436-156 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O15013-5(isoform-parent) refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:4nooxkCzYKDyfRBmHGoaBa26bbE9606 rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606 rigid:Q9IrAHfI25KgjTYo839bCiGl8j4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15013-5 uniprotkb:P27986 intact:EBI-25409011 intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19 psi-mi:o150135(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409018|imex:IM-26436-156 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O15013-5(isoform-parent) refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:4nooxkCzYKDyfRBmHGoaBa26bbE9606 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 rigid:Q9IrAHfI25KgjTYo839bCiGl8j4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15013-5 uniprotkb:P25685 intact:EBI-25409011 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:o150135(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409018|imex:IM-26436-156 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O15013-5(isoform-parent) dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:4nooxkCzYKDyfRBmHGoaBa26bbE9606 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 rigid:Q9IrAHfI25KgjTYo839bCiGl8j4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15013-5 uniprotkb:Q8N4T4 intact:EBI-25409011 intact:EBI-745468|uniprotkb:Q49AG0|uniprotkb:Q6TPQ2|uniprotkb:Q96ST6|ensembl:ENSP00000367638 psi-mi:o150135(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:arg39_human(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409018|imex:IM-26436-156 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O15013-5(isoform-parent) refseq:NP_116207.2|ensembl:ENSG00000137135(gene)|ensembl:ENST00000378387(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0030335"(positive regulation of cell migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR042987|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:4nooxkCzYKDyfRBmHGoaBa26bbE9606 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rigid:Q9IrAHfI25KgjTYo839bCiGl8j4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15013-5 uniprotkb:Q9HCE6 intact:EBI-25409011 intact:EBI-724864|uniprotkb:Q6P0L7|uniprotkb:Q8NAV5|uniprotkb:Q9NVT3|uniprotkb:Q17RW1|uniprotkb:Q3YFJ4|uniprotkb:Q5VXI5|uniprotkb:Q5VXI6|uniprotkb:Q66K51|uniprotkb:B7ZKS1|ensembl:ENSP00000355060 psi-mi:o150135(display_long)|uniprotkb:ARHGEF10(gene name)|psi-mi:ARHGEF10(display_short)|uniprotkb:KIAA0294(gene name synonym) psi-mi:argal_human(display_long)|uniprotkb:GRINCHGEF(gene name synonym)|uniprotkb:KIAA1626(gene name synonym)|uniprotkb:GrinchGEF(gene name synonym)|uniprotkb:ARHGEF10L(gene name)|psi-mi:ARHGEF10L(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409018|imex:IM-26436-156 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O15013-5(isoform-parent) refseq:NP_001306766.1|refseq:NP_001306767.1|refseq:NP_001011722.2|refseq:NP_060595.3|ensembl:ENSG00000074964(gene)|ensembl:ENST00000361221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|refseq:NP_001315053.1|refseq:XP_005245982.2|refseq:XP_016857106.1|refseq:XP_016857110.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:4nooxkCzYKDyfRBmHGoaBa26bbE9606 rogid:HWnqkCHhpqMiOEwoYw8Uhfn8N+w9606 rigid:Q9IrAHfI25KgjTYo839bCiGl8j4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z6J4 uniprotkb:Q811M1 intact:EBI-1057190|uniprotkb:Q5T8I1|uniprotkb:Q6P6A8|uniprotkb:Q6ZNL5|uniprotkb:Q8IZ32|uniprotkb:Q8N868|uniprotkb:Q9H7M2|ensembl:ENSP00000274963 intact:EBI-25408977|ensembl:ENSMUSP00000056461|uniprotkb:Q3T9M8|uniprotkb:Q3TCU0|uniprotkb:Q8C0I5|uniprotkb:Q8JZY0 psi-mi:fgd2_human(display_long)|uniprotkb:FGD2(gene name)|psi-mi:FGD2(display_short)|uniprotkb:ZFYVE4(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 4(gene name synonym) psi-mi:rhg15_mouse(display_long)|uniprotkb:ArhGAP15(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 15(gene name synonym)|uniprotkb:Arhgap15(gene name)|psi-mi:Arhgap15(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409003|imex:IM-26436-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775829.2|ensembl:ENSG00000146192(gene)|ensembl:ENST00000274963(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037797|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 ensembl:ENSMUSG00000049744(gene)|ensembl:ENSMUST00000055776(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-MMU-9013149|reactome:R-MMU-9013423|refseq:NP_722542.2|refseq:XP_006498462.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:jAx/1RNr9M1EoPP9w6wks8dRLaA9606 rogid:FP9dKRGbk2BxALjNSkSZbfQG14010090 rigid:ousB5cRQ9ScX8oFdaKtVE6nxNtc false - tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HP0 uniprotkb:O15371 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1 psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408957|imex:IM-26436-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606 rigid:HK4S1llwgVwQLpJYxxM7Ej0KgBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HP0 uniprotkb:O00232 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15 psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408957|imex:IM-26436-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606 rigid:HK4S1llwgVwQLpJYxxM7Ej0KgBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HP0 uniprotkb:O75427 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689 psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408957|imex:IM-26436-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_002310.2|refseq:NP_001276863.1|ensembl:ENSG00000077454(gene)|ensembl:ENST00000310300(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0016605"(PML body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606 rigid:HK4S1llwgVwQLpJYxxM7Ej0KgBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HP0 uniprotkb:Q96II8 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579 psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408957|imex:IM-26436-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606 rigid:HK4S1llwgVwQLpJYxxM7Ej0KgBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HP0 uniprotkb:Q9Y2L9 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 intact:EBI-2797324|uniprotkb:Q7Z5F7|uniprotkb:Q7Z5F6|uniprotkb:Q5TBU9|uniprotkb:Q2KHR1|uniprotkb:B7ZLL5|uniprotkb:F8W6F0|uniprotkb:Q17R43|ensembl:ENSP00000374448 psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:lrch1_human(display_long)|uniprotkb:CHDC1(gene name synonym)|uniprotkb:KIAA1016(gene name synonym)|uniprotkb:Calponin homology domain-containing protein 1(gene name synonym)|uniprotkb:Neuronal protein 81(gene name synonym)|uniprotkb:LRCH1(gene name)|psi-mi:LRCH1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408957|imex:IM-26436-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_001157685.1|refseq:NP_055931.1|refseq:NP_001157683.1|ensembl:ENSG00000136141(gene)|ensembl:ENST00000389798(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rogid:3oNqV4dI/4ZHz1sUSsc8nmg0j049606 rigid:HK4S1llwgVwQLpJYxxM7Ej0KgBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HP0 uniprotkb:Q9Y6G9 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 intact:EBI-2556107|uniprotkb:A2RRG7|uniprotkb:Q53HK7|uniprotkb:Q53HC8|ensembl:ENSP00000273130 psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:dc1l1_human(display_long)|uniprotkb:DNCLI1(gene name synonym)|uniprotkb:Dynein light intermediate chain 1, cytosolic(gene name synonym)|uniprotkb:Dynein light chain A(gene name synonym)|uniprotkb:DYNC1LI1(gene name)|psi-mi:DYNC1LI1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408957|imex:IM-26436-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_057225.2|ensembl:ENSG00000144635(gene)|ensembl:ENST00000273130(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0051301"(cell division)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|interpro:IPR027417|mint:Q9Y6G9|rcsb pdb:6B9H|rcsb pdb:6PSD|rcsb pdb:6PSE|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0007018"(microtubule-based movement) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rogid:LxQSfBpzuf6Acus2jBy0s53FdhU9606 rigid:HK4S1llwgVwQLpJYxxM7Ej0KgBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HP0 uniprotkb:P10515 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 intact:EBI-2959723|ensembl:ENSP00000280346|uniprotkb:Q16783|uniprotkb:Q53EP3 psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:odp2_human(display_long)|uniprotkb:DLAT(gene name)|psi-mi:DLAT(display_short)|uniprotkb:DLTA(gene name synonym)|uniprotkb:70 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:M2 antigen complex 70 kDa subunit(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25408957|imex:IM-26436-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_001922.2|ensembl:ENSG00000150768(gene)|ensembl:ENST00000280346(transcript)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P10515|rcsb pdb:1FYC|rcsb pdb:1Y8N|rcsb pdb:1Y8O|rcsb pdb:1Y8P|rcsb pdb:2DNE|rcsb pdb:2PNR|rcsb pdb:2Q8I|rcsb pdb:3B8K|rcsb pdb:3CRK|rcsb pdb:3CRL|rcsb pdb:6CT0|rcsb pdb:6H55|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268|dip:DIP-29496N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rogid:Owh80Cm4CXvo2rPKUhLGc/U47co9606 rigid:HK4S1llwgVwQLpJYxxM7Ej0KgBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q9NZ01 intact:EBI-25409036 intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:P22102 intact:EBI-25409036 intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:O95292 intact:EBI-25409036 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q9P0L0 intact:EBI-25409036 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:P62987 intact:EBI-25409036 intact:EBI-357304|ensembl:ENSP00000388107|ensembl:ENSP00000396910|ensembl:ENSP00000470419|ensembl:ENSP00000470507|ensembl:ENSP00000471062|ensembl:ENSP00000471464|ensembl:ENSP00000471622|ensembl:ENSP00000472264|ensembl:ENSP00000472545|ensembl:ENSP00000473048|uniprotkb:P14793|uniprotkb:Q9BX98|uniprotkb:Q9UPK7|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:rl40_human(display_long)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:Ubiquitin A-52 residue ribosomal protein fusion product 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) ensembl:ENSG00000221983(gene)|ensembl:ENST00000430157(transcript)|ensembl:ENST00000442744(transcript)|ensembl:ENST00000595158(transcript)|rcsb pdb:2MBH|rcsb pdb:2MJB|rcsb pdb:2MUR|ensembl:ENST00000595683(transcript)|ensembl:ENST00000596273(transcript)|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBD|ensembl:ENST00000596304(transcript)|rcsb pdb:2NBE|rcsb pdb:2RSU|rcsb pdb:4HJK|ensembl:ENST00000597451(transcript)|ensembl:ENST00000598780(transcript)|rcsb pdb:4JIO|rcsb pdb:4P4H|rcsb pdb:4PIG|ensembl:ENST00000599551(transcript)|ensembl:ENST00000599595(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:4PIH|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017085"(response to insecticide)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|mint:P62987|rcsb pdb:2LJ5|rcsb pdb:4PIJ|rcsb pdb:4RF0|rcsb pdb:4S1Z|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XKL|rcsb pdb:5AJ0|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5HPK|rcsb pdb:5HPL|rcsb pdb:5HPS|rcsb pdb:5HPT|rcsb pdb:5J26|rcsb pdb:5J8P|rcsb pdb:5JBV|rcsb pdb:5JBY|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:4RF1|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7AY1|rcsb pdb:7BHP|rcsb pdb:7M3Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|rcsb pdb:6Z6N|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-69231|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|refseq:NP_001029102.1|refseq:NP_003324.1|refseq:NP_001307947.1|refseq:NP_001307948.1|refseq:NP_001307949.1|refseq:NP_001307946.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:x9O/Pbww4D28M1+hIj+p0xrUXgU9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q15654 intact:EBI-25409036 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q9BSH4 intact:EBI-25409036 intact:EBI-747797|uniprotkb:Q8N3N6|uniprotkb:Q9UI60|uniprotkb:B2RD21|ensembl:ENSP00000258975 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:taco1_human(display_long)|uniprotkb:PRO0477(orf name)|uniprotkb:TACO1(gene name)|psi-mi:TACO1(display_short)|uniprotkb:CCDC44(gene name synonym)|uniprotkb:Translational activator of mitochondrially-encoded cytochrome c oxidase I(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 44(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_057444.2|ensembl:ENSG00000136463(gene)|ensembl:ENST00000258975(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0019843"(rRNA binding)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0061743"(motor learning)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR026564|interpro:IPR029072|mint:Q9BSH4|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:c/tu89NvCs3Kt8qO8e5F6hrywBo9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q08170 intact:EBI-25409036 intact:EBI-722621|uniprotkb:Q5VXP1|uniprotkb:Q9BUA4|ensembl:ENSP00000362900|uniprotkb:Q9UEB5 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:srsf4_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP75(gene name synonym)|uniprotkb:SRP001LB(gene name synonym)|uniprotkb:SFRS4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:SRSF4(gene name)|psi-mi:SRSF4(display_short)|uniprotkb:SRP75(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_005617.2|ensembl:ENSG00000116350(gene)|ensembl:ENST00000373795(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q08170|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:LVIhOlsJ8rUYB68fWFDsovUGTeU9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:P08195 intact:EBI-25409036 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q15019 intact:EBI-25409036 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N - - crc64:12CCBBE30806F92F figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q96QC0 intact:EBI-25409036 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q8WUA2 intact:EBI-25409036 intact:EBI-2513119|ensembl:ENSP00000253329|uniprotkb:B2RD34|uniprotkb:Q7Z3Q5 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:ppil4_human(display_long)|uniprotkb:PPIL4(gene name)|psi-mi:PPIL4(display_short)|uniprotkb:Cyclophilin-like protein PPIL4(gene name synonym)|uniprotkb:Rotamase PPIL4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029000|interpro:IPR035538|interpro:IPR035542|interpro:IPR035979|mint:Q8WUA2|reactome:R-HSA-72163|go:"GO:0005829"(cytosol)|ensembl:ENSG00000131013(gene)|ensembl:ENST00000253329(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_624311.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:kxM/VRcLUG5M5FAlHuuAKRBKrd89606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q9UGP4 intact:EBI-25409036 intact:EBI-2652871|uniprotkb:Q17RQ1|uniprotkb:Q9BQQ9|uniprotkb:Q9NQ47|ensembl:ENSP00000273317 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:limd1_human(display_long)|uniprotkb:LIMD1(gene name)|psi-mi:LIMD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_055055.1|ensembl:ENSG00000144791(gene)|ensembl:ENST00000273317(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016310"(phosphorylation)|go:"GO:0016442"(RISC complex)|go:"GO:0016477"(cell migration)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028734|reactome:R-HSA-1234176 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:Eq6aJ83PR4G/LIlUi5H2Bv31sTQ9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q12849 intact:EBI-25409036 intact:EBI-1054150|uniprotkb:Q6ZST3|uniprotkb:Q8NBD2|uniprotkb:Q4W5S5|uniprotkb:Q8IWD6|uniprotkb:B3KPW0|intact:EBI-28981368|ensembl:ENSP00000254799 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:grsf1_human(display_long)|uniprotkb:GRSF1(gene name)|psi-mi:GRSF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_002083.3|refseq:XP_011530199.1|ensembl:ENSP00000254799|ensembl:ENST00000502323|ensembl:ENSP00000425430|refseq:NP_001091947.1|ensembl:ENSG00000132463(gene)|ensembl:ENST00000254799(transcript)|go:"GO:0000962"(positive regulation of mitochondrial RNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033106|interpro:IPR034424|interpro:IPR034425|interpro:IPR034426|interpro:IPR035979|rcsb pdb:2LMI|rcsb pdb:4QU6|rcsb pdb:4QU7|reactome:R-HSA-192823 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:89Xul87okYruMW1PQtPMbBTqX+09606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:P00367 intact:EBI-25409036 intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865|uniprotkb:B3KV55|uniprotkb:B4DGN5 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) ensembl:ENSG00000148672(gene)|ensembl:ENST00000277865(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042802"(identical protein binding)|refseq:NP_005262.1|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|reactome:R-HSA-2151201|reactome:R-HSA-8964539 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q9H3G5 intact:EBI-25409036 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:P20674 intact:EBI-25409036 intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q07065 intact:EBI-25409036 intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q9NWU2 intact:EBI-25409036 intact:EBI-1051077|uniprotkb:Q8N5M5|uniprotkb:E1P5I3|ensembl:ENSP00000266069 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:gid8_human(display_long)|uniprotkb:GID8(gene name)|psi-mi:GID8(display_short)|uniprotkb:C20orf11(gene name synonym)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym)|uniprotkb:TWA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_060366.1|ensembl:ENSG00000101193(gene)|ensembl:ENST00000266069(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9NWU2|rcsb pdb:7NSC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:P0HsK72KT6OPKKw7lVSJ/FiY4CU9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q9H7C9 intact:EBI-25409036 intact:EBI-10308705|uniprotkb:Q9Y6B1|uniprotkb:Q96AQ4|ensembl:ENSP00000377078|ensembl:ENSP00000431808 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:aamdc_human(display_long)|uniprotkb:AAMDC(gene name)|psi-mi:AAMDC(display_short)|uniprotkb:Adipogenesis associated Mth938 domain-containing protein(gene name synonym)|uniprotkb:C11orf67(gene name synonym)|uniprotkb:PTD015(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) refseq:NP_001303886.1|refseq:NP_001303889.1|refseq:NP_001303890.1|refseq:NP_001303891.1|refseq:NP_078960.1|refseq:XP_011543271.1|ensembl:ENSG00000087884(gene)|ensembl:ENST00000393427(transcript)|ensembl:ENST00000526415(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045600"(positive regulation of fat cell differentiation)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034096|interpro:IPR036748|mint:Q9H7C9|rcsb pdb:2AB1|rcsb pdb:2Q4Q - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:K1kfbdCxyGTAglEl+pDfu4NjjMs9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:O43182 intact:EBI-25409036 intact:EBI-20720685|intact:EBI-28977626|ensembl:ENSP00000338967|uniprotkb:B2RWQ0|uniprotkb:O43437|uniprotkb:Q9P1B3|uniprotkb:Q9UK81|uniprotkb:Q9UK82 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:rhg06_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 6(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RhoGAPX-1(gene name synonym)|uniprotkb:ARHGAP6(gene name)|psi-mi:ARHGAP6(display_short)|uniprotkb:RHOGAP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) ensembl:ENST00000303025|ensembl:ENSP00000302312|ensembl:ENSP00000338967|ensembl:ENST00000380718|ensembl:ENSP00000370094|ensembl:ENST00000380736|ensembl:ENSP00000370112|ensembl:ENST00000495242|ensembl:ENSP00000435767|ensembl:ENSG00000047648(gene)|ensembl:ENST00000337414(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR030772|interpro:IPR037863|interpro:IPR041852|reactome:R-HSA-8980692|reactome:R-HSA-9013423|refseq:NP_001274171.1|refseq:NP_006116.2|refseq:NP_038267.1|refseq:NP_038286.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:vkyq8e0fxup//XXOYIWi+ZlBLww9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q640N3-2 uniprotkb:Q96IF1 intact:EBI-25409036 intact:EBI-949782|intact:EBI-28987773|ensembl:ENSP00000262713|ensembl:ENSP00000354491|uniprotkb:D3DS37|uniprotkb:A8MX18 psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:ajuba_human(display_long)|uniprotkb:AJUBA(gene name)|psi-mi:AJUBA(display_short)|uniprotkb:JUB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409042|imex:IM-26436-254 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q640N3-2(isoform-parent) go:"GO:0045294"(alpha-catenin binding)|go:"GO:0046474"(glycerophospholipid biosynthetic process)|go:"GO:0030027"(lamellipodium)|go:"GO:0046872"(metal ion binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031328"(positive regulation of cellular biosynthetic process)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:0034613"(cellular protein localization)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q96IF1|go:"GO:0035195"(gene silencing by miRNA)|reactome:R-HSA-1234176|reactome:R-HSA-2565942|reactome:R-HSA-5617472|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|ensembl:ENSG00000129474(gene)|ensembl:ENST00000262713(transcript)|ensembl:ENST00000361265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|refseq:NP_116265.1|refseq:NP_932352.1|ensembl:ENSP00000262713|ensembl:ENSP00000354491|ensembl:ENST00000397388|ensembl:ENSP00000380543|refseq:NP_001276026.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rogid:l3GAffQ5t7Cfb9iQLE/hdyNQwbw9606 rigid:bjr97CSnCjjzMaAnFgqC97zc5qA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q9H9B4 intact:EBI-25409092 intact:EBI-355861|uniprotkb:Q9HA53|uniprotkb:B3KPW3|uniprotkb:D3DQN2|ensembl:ENSP00000316905 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:sfxn1_human(display_long)|uniprotkb:SFXN1(gene name)|psi-mi:SFXN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_073591.2|refseq:NP_001309906.1|ensembl:ENSG00000164466(gene)|ensembl:ENST00000321442(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015825"(L-serine transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042942"(D-serine transport)|go:"GO:0042945"(D-serine transmembrane transporter activity)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q9H9B4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:n/i6d8Rt+xMOvu3BrZfc0VP0+Wk9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:P50454 intact:EBI-25409092 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q16576 intact:EBI-25409092 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q9P035 intact:EBI-25409092 intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:O00264 intact:EBI-25409092 intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q8N1F7 intact:EBI-25409092 intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:pkk5pooUC4yQShpqjiwNLddfy149606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q92621 intact:EBI-25409092 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q9NX20 intact:EBI-25409092 intact:EBI-2560190|uniprotkb:Q9HB70|uniprotkb:Q9BYD0|ensembl:ENSP00000300151 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:rm16_human(display_long)|uniprotkb:MRPL16(gene name)|psi-mi:MRPL16(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL16m(gene name synonym)|uniprotkb:PNAS-111(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_060310.1|ensembl:ENSG00000166902(gene)|ensembl:ENST00000300151(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000114(Ribosomal protein L16)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR036920|mint:Q9NX20|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:5ngQm8RUtN0SGgxJN2mGtWKhHMU9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q14739 intact:EBI-25409092 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q14697 intact:EBI-25409092 intact:EBI-348004|ensembl:ENSP00000349053|uniprotkb:A6NC20|uniprotkb:Q8WTS9|uniprotkb:Q9P0X0 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:ganab_human(display_long)|uniprotkb:GANAB(gene name)|psi-mi:GANAB(display_short)|uniprotkb:G2AN(gene name synonym)|uniprotkb:KIAA0088(gene name synonym)|uniprotkb:Glucosidase II subunit alpha(gene name synonym)|uniprotkb:Alpha-glucosidase 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) ensembl:ENSG00000089597(gene)|ensembl:ENST00000356638(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006491"(N-glycan processing)|go:"GO:0016020"(membrane)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0033919"(glucan 1,3-alpha-glucosidase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090599"(alpha-glucosidase activity)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|mint:Q14697|reactome:R-HSA-532668|reactome:R-HSA-901042|reactome:R-HSA-9694548|reactome:R-HSA-9683686|refseq:NP_938148.1|refseq:NP_938149.2|refseq:NP_001265121.1|refseq:NP_001265122.1|refseq:NP_001265123.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:663u1GYwNTZrodoVqwzFjSDGCqs9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:P39656 intact:EBI-25409092 intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q10570 intact:EBI-25409092 intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:Q8IVM0 intact:EBI-25409092 intact:EBI-723996|intact:EBI-28978624|ensembl:ENSP00000376250|uniprotkb:Q86VH7 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:ccd50_human(display_long)|uniprotkb:Protein Ymer(gene name synonym)|uniprotkb:CCDC50(gene name)|psi-mi:CCDC50(display_short)|uniprotkb:C3orf6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_777568.1|refseq:NP_848018.1|ensembl:ENSG00000152492(gene)|ensembl:ENST00000392456(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR029311|interpro:IPR039303|rcsb pdb:6LAN|ensembl:ENST00000392455|ensembl:ENSP00000376249|ensembl:ENSP00000376250 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:KXHuNkpMuvUCHFpMGG8D6kPUrgQ9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CB8-1 uniprotkb:P36542 intact:EBI-25409092 intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142 psi-mi:q14cb81(display_long)|uniprotkb:ARHGAP19(gene name)|psi-mi:ARHGAP19(display_short) psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409097|imex:IM-26436-82 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q14CB8-1(isoform-parent) refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v5rtU+Jo9PYV5zC2Fnk7uRSx3dQ9606 rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606 rigid:+MwCu1rU0tMrW17ABuFbkWRMC/k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7D0-1 uniprotkb:Q8IVS2 intact:EBI-25409131 intact:EBI-1210664|uniprotkb:B0QY72|uniprotkb:O95510|uniprotkb:O95511|ensembl:ENSP00000290429 psi-mi:q9h7d01(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short) psi-mi:fabd_human(display_long)|uniprotkb:MCAT(gene name)|psi-mi:MCAT(display_short)|uniprotkb:MT(gene name synonym)|uniprotkb:Mitochondrial malonyltransferase(gene name synonym)|uniprotkb:[Acyl-carrier-protein] malonyltransferase(gene name synonym)|uniprotkb:"Mitochondrial malonyl CoA:ACP acyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409137|imex:IM-26436-116 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9H7D0-1(isoform-parent) refseq:NP_055322.1|refseq:NP_775738.3|ensembl:ENSG00000100294(gene)|ensembl:ENST00000290429(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004312"(fatty acid synthase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|interpro:IPR001227(Acyl transferase region)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|rcsb pdb:2C2N|reactome:R-HSA-77289 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606 rogid:6Uw/NgJstPl1ycA9jOFqnocYyPM9606 rigid:Fls14ozWq1wlj8y5i16RkwqQ5I4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7D0-1 uniprotkb:Q96JJ3 intact:EBI-25409131 intact:EBI-3959230|ensembl:ENSP00000290246|ensembl:ENSP00000379673|uniprotkb:Q9NQQ6|uniprotkb:Q5JVZ6|uniprotkb:E1P5T3|uniprotkb:Q9HAH0|uniprotkb:Q9H9L5|uniprotkb:Q9H938|uniprotkb:Q96PA9|uniprotkb:Q96CJ2|uniprotkb:Q96ME5|uniprotkb:Q7Z5G9 psi-mi:q9h7d01(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short) psi-mi:elmo2_human(display_long)|uniprotkb:ELMO2(gene name)|psi-mi:ELMO2(display_short)|uniprotkb:CED12A(gene name synonym)|uniprotkb:KIAA1834(gene name synonym)|uniprotkb:Protein ced-12 homolog A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409137|imex:IM-26436-116 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9H7D0-1(isoform-parent) ensembl:ENSG00000062598(gene)|ensembl:ENST00000290246(transcript)|ensembl:ENST00000396391(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0048870"(cell motility)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR030713|rcsb pdb:6IDX|rcsb pdb:6IE1|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013408|reactome:R-HSA-9664422|refseq:NP_001305182.1|refseq:NP_573403.1|refseq:NP_877496.1|refseq:XP_005260553.1|refseq:XP_006723917.1|refseq:XP_005260555.1|refseq:XP_005260556.1|refseq:XP_005260557.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606 rogid:dXWjmEDxNMqr2k3/jdmSPB35MM49606 rigid:Fls14ozWq1wlj8y5i16RkwqQ5I4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7D0-1 uniprotkb:Q92556 intact:EBI-25409131 intact:EBI-346417|uniprotkb:Q29R79|uniprotkb:Q96PB0|uniprotkb:Q9H0I1|uniprotkb:A4D1X6|uniprotkb:Q6ZTJ0|ensembl:ENSP00000312185|ensembl:ENSP00000394458|ensembl:ENSP00000406952 psi-mi:q9h7d01(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short) psi-mi:elmo1_human(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409137|imex:IM-26436-116 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9H7D0-1(isoform-parent) refseq:XP_006715868.1|refseq:NP_569709.1|refseq:XP_005249976.1|refseq:NP_001034548.1|refseq:NP_001193409.1|refseq:NP_001193411.1|refseq:NP_055615.8|refseq:XP_011513956.1|refseq:XP_016868327.1|refseq:XP_016868328.1|dip:DIP-31095N|ensembl:ENSG00000155849(gene)|ensembl:ENST00000310758(transcript)|ensembl:ENST00000442504(transcript)|ensembl:ENST00000448602(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0048870"(cell motility)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR030715|mint:Q92556|rcsb pdb:2RQR|rcsb pdb:2VSZ|rcsb pdb:3A98|rcsb pdb:6JPP|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9664422 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606 rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606 rigid:Fls14ozWq1wlj8y5i16RkwqQ5I4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7D0-1 uniprotkb:Q14185 intact:EBI-25409131 intact:EBI-446740|uniprotkb:A9Z1Z5|ensembl:ENSP00000280333 psi-mi:q9h7d01(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short) psi-mi:dock1_human(display_long)|uniprotkb:180 kDa protein downstream of CRK(gene name synonym)|uniprotkb:DOCK1(gene name)|psi-mi:DOCK1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409137|imex:IM-26436-116 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9H7D0-1(isoform-parent) ensembl:ENSP00000280333|dip:DIP-29391N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000150760(gene)|ensembl:ENST00000280333(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|mint:Q14185|rcsb pdb:3L4C|reactome:R-HSA-2029482|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9664422|reactome:R-HSA-983231|interpro:IPR043162|refseq:NP_001371.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606 rogid:SsN4jN+OIbDOnPEthCF7ZdEJrdc9606 rigid:Fls14ozWq1wlj8y5i16RkwqQ5I4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7D0-1 uniprotkb:Q6NXT1 intact:EBI-25409131 intact:EBI-10102770|uniprotkb:Q6ZSB1|uniprotkb:Q9UGV1|intact:EBI-28972042|ensembl:ENSP00000215941 psi-mi:q9h7d01(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short) psi-mi:anr54_human(display_long)|uniprotkb:ANKRD54(gene name)|psi-mi:ANKRD54(display_short)|uniprotkb:LIAR(gene name synonym)|uniprotkb:Lyn-interacting ankyrin repeat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409137|imex:IM-26436-116 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9H7D0-1(isoform-parent) ensembl:ENSP00000215941|refseq:NP_620152.1|ensembl:ENSG00000100124(gene)|ensembl:ENST00000215941(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:1902531"(regulation of intracellular signal transduction)|interpro:IPR002110(Ankyrin)|interpro:IPR036770 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606 rogid:Ku7TbISn+yxM8+a5FED4ANkydEg9606 rigid:Fls14ozWq1wlj8y5i16RkwqQ5I4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RTY4 uniprotkb:P12268 intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250 intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584 psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym) psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409153|imex:IM-26436-84 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424 refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606 rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606 rigid:Sso+FjHSPrIiQJvXCu4RlT4QfAs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RTY4 uniprotkb:Q9H3U1 intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250 intact:EBI-1048763|uniprotkb:Q7L3Y6|uniprotkb:Q9H3U8|uniprotkb:Q9NSE8|uniprotkb:Q9NSE9|uniprotkb:A8K6F7|ensembl:ENSP00000407487 psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym) psi-mi:un45a_human(display_long)|uniprotkb:GCUNC-45(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 1(gene name synonym)|uniprotkb:UNC45A(gene name)|psi-mi:UNC45A(display_short)|uniprotkb:SMAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409153|imex:IM-26436-84 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424 refseq:NP_001034764.1|refseq:NP_061141.2|refseq:XP_011520081.1|ensembl:ENSG00000140553(gene)|ensembl:ENST00000418476(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019734|interpro:IPR024660|rcsb pdb:2DBA|refseq:NP_001310548.1|refseq:NP_001310550.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606 rogid:P/N+VqGUtK2vWzHyKq6UzC4xxdo9606 rigid:Sso+FjHSPrIiQJvXCu4RlT4QfAs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RTY4 uniprotkb:P04637 intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409153|imex:IM-26436-84 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424 refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rigid:Sso+FjHSPrIiQJvXCu4RlT4QfAs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RTY4 uniprotkb:P52948 intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409153|imex:IM-26436-84 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424 refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 rigid:Sso+FjHSPrIiQJvXCu4RlT4QfAs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RTY4 uniprotkb:O75947 intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250 intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6 psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym) psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409153|imex:IM-26436-84 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424 refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606 rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606 rigid:Sso+FjHSPrIiQJvXCu4RlT4QfAs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96Q42 uniprotkb:Q9BUL8 intact:EBI-1044902|uniprotkb:Q8N1E0|uniprotkb:Q96PC4|uniprotkb:Q96Q41|uniprotkb:Q9H973|uniprotkb:Q9HCK9|uniprotkb:Q53TT1|uniprotkb:Q53TV2|ensembl:ENSP00000264276|ensembl:ENSP00000505043|ensembl:ENSP00000505092|ensembl:ENSP00000505187|ensembl:ENSP00000505218 intact:EBI-740195|uniprotkb:O14811|uniprotkb:D3DNN5|ensembl:ENSP00000376506|ensembl:ENSP00000417202|ensembl:ENSP00000418317|ensembl:ENSP00000420021|ensembl:ENSP00000420553|uniprotkb:A8K515|intact:EBI-2556229 psi-mi:als2_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein(gene name synonym)|uniprotkb:ALS2(gene name)|psi-mi:ALS2(display_short)|uniprotkb:KIAA1563(gene name synonym)|uniprotkb:ALS2CR6(gene name synonym) psi-mi:pdc10_human(display_long)|uniprotkb:PDCD10(gene name)|psi-mi:PDCD10(display_short)|uniprotkb:CCM3(gene name synonym)|uniprotkb:TFAR15(gene name synonym)|uniprotkb:TF-1 cell apoptosis-related protein 15(gene name synonym)|uniprotkb:Cerebral cavernous malformations 3 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409169|imex:IM-26436-306 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129217.1|refseq:NP_065970.2|interpro:IPR037191|reactome:R-HSA-8876198|reactome:R-HSA-9013149|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003409(MORN motif)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|ensembl:ENSG00000003393(gene)|ensembl:ENST00000264276(transcript)|ensembl:ENST00000679435(transcript)|ensembl:ENST00000679516(transcript)|ensembl:ENST00000680163(transcript)|ensembl:ENST00000680861(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007032"(endosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008104"(protein localization)|go:"GO:0008219"(cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042802"(identical protein binding)|ensembl:ENSP00000264276|ensembl:ENST00000409632|ensembl:ENSP00000386384|ensembl:ENST00000467448|ensembl:ENSP00000429223|ensembl:ENSP00000505218|ensembl:ENST00000679503|ensembl:ENSP00000505968|ensembl:ENSP00000505187|ensembl:ENSP00000505092|ensembl:ENST00000680188|ensembl:ENSP00000505665|ensembl:ENSP00000505043|refseq:XP_006712717.1 ensembl:ENSG00000114209(gene)|ensembl:ENST00000392750(transcript)|ensembl:ENST00000461494(transcript)|ensembl:ENST00000470131(transcript)|ensembl:ENST00000473645(transcript)|ensembl:ENST00000497056(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009652(Protein of unknown function DUF1241)|rcsb pdb:3AJM|rcsb pdb:3L8I|rcsb pdb:3L8J|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3W8H|rcsb pdb:3W8I|rcsb pdb:4GEH|rcsb pdb:4TVQ|refseq:NP_009148.2|refseq:NP_665858.1|refseq:NP_665859.1|refseq:XP_011510670.1|refseq:XP_011510671.1|refseq:XP_005247143.1|refseq:XP_005247144.1|refseq:XP_005247145.1|refseq:XP_006713548.1|refseq:XP_016861133.1|dip:DIP-40607N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/CbIkwBlU9LPad9mVvtQAgsHwmk9606 rogid:BVHrFpHNErUWVLO0A48Un1COLhM9606 rigid:HE04UHoqPNfZT2jzCZR79J/sshc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96Q42 uniprotkb:P52757 intact:EBI-1044902|uniprotkb:Q8N1E0|uniprotkb:Q96PC4|uniprotkb:Q96Q41|uniprotkb:Q9H973|uniprotkb:Q9HCK9|uniprotkb:Q53TT1|uniprotkb:Q53TV2|ensembl:ENSP00000264276|ensembl:ENSP00000505043|ensembl:ENSP00000505092|ensembl:ENSP00000505187|ensembl:ENSP00000505218 intact:EBI-714925|uniprotkb:Q2M203|uniprotkb:Q75MM2|uniprotkb:A4D1A2|uniprotkb:F8QPL9|ensembl:ENSP00000222792|uniprotkb:E9PGE0|uniprotkb:B3VCF1|uniprotkb:B3VCF2|uniprotkb:B3VCF3|uniprotkb:C9J7B0|uniprotkb:B3VCF7|uniprotkb:B3VCG1 psi-mi:als2_human(display_long)|uniprotkb:Amyotrophic lateral sclerosis 2 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein(gene name synonym)|uniprotkb:ALS2(gene name)|psi-mi:ALS2(display_short)|uniprotkb:KIAA1563(gene name synonym)|uniprotkb:ALS2CR6(gene name synonym) psi-mi:chio_human(display_long)|uniprotkb:Beta-chimerin(gene name synonym)|uniprotkb:Rho GTPase-activating protein 3(gene name synonym)|uniprotkb:CHN2(gene name)|psi-mi:CHN2(display_short)|uniprotkb:ARHGAP3(gene name synonym)|uniprotkb:BCH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409169|imex:IM-26436-306 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129217.1|refseq:NP_065970.2|interpro:IPR037191|reactome:R-HSA-8876198|reactome:R-HSA-9013149|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR003409(MORN motif)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|ensembl:ENSG00000003393(gene)|ensembl:ENST00000264276(transcript)|ensembl:ENST00000679435(transcript)|ensembl:ENST00000679516(transcript)|ensembl:ENST00000680163(transcript)|ensembl:ENST00000680861(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0001881"(receptor recycling)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007032"(endosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008104"(protein localization)|go:"GO:0008219"(cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042802"(identical protein binding)|ensembl:ENSP00000264276|ensembl:ENST00000409632|ensembl:ENSP00000386384|ensembl:ENST00000467448|ensembl:ENSP00000429223|ensembl:ENSP00000505218|ensembl:ENST00000679503|ensembl:ENSP00000505968|ensembl:ENSP00000505187|ensembl:ENSP00000505092|ensembl:ENST00000680188|ensembl:ENSP00000505665|ensembl:ENSP00000505043|refseq:XP_006712717.1 refseq:NP_001279998.1|refseq:NP_001279999.1|refseq:NP_001280000.1|refseq:NP_001280002.1|refseq:NP_001280004.1|refseq:NP_001280005.1|refseq:NP_001280006.1|refseq:NP_001280007.1|refseq:NP_001280008.1|refseq:NP_001280009.1|refseq:NP_001035025.1|refseq:NP_004058.1|interpro:IPR036860|interpro:IPR037860|mint:P52757|rcsb pdb:1XA6|reactome:R-HSA-9013149|interpro:IPR035840|ensembl:ENSG00000106069(gene)|ensembl:ENST00000222792(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR017356(N-chimaerin)|interpro:IPR020454 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/CbIkwBlU9LPad9mVvtQAgsHwmk9606 rogid:drcrV4yAbGTuSAJYNjjopBQxFDM9606 rigid:HE04UHoqPNfZT2jzCZR79J/sshc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94988-4 uniprotkb:Q16537 intact:EBI-25409179 intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9 psi-mi:o949884(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym)|uniprotkb:FAM13A1_v2(isoform synonym) psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409188|imex:IM-26436-86 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94988-4(isoform-parent) ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606 rigid:em1qIxD1gKKZmpAfQmri3XHoafk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94988-4 uniprotkb:Q13362 intact:EBI-25409179 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:o949884(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym)|uniprotkb:FAM13A1_v2(isoform synonym) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409188|imex:IM-26436-86 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94988-4(isoform-parent) refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 rigid:em1qIxD1gKKZmpAfQmri3XHoafk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94988-4 uniprotkb:Q9Y5P8 intact:EBI-25409179 intact:EBI-2479826|intact:EBI-28984956|ensembl:ENSP00000375080|uniprotkb:Q6P4G9|uniprotkb:Q7RTT1|uniprotkb:Q96H01 psi-mi:o949884(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym)|uniprotkb:FAM13A1_v2(isoform synonym) psi-mi:p2r3b_human(display_long)|uniprotkb:PPP2R3B(gene name)|psi-mi:PPP2R3B(display_short)|uniprotkb:PPP2R3L(gene name synonym)|uniprotkb:Protein phosphatase 2A 48 kDa regulatory subunit(gene name synonym)|uniprotkb:PP2A subunit B isoform PR48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409188|imex:IM-26436-86 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94988-4(isoform-parent) ensembl:ENSG00000167393(gene)|ensembl:ENST00000390665(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR041534|mint:Q9Y5P8|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4MEW|reactome:R-HSA-113501|reactome:R-HSA-69231|reactome:R-HSA-69273|go:"GO:0005654"(nucleoplasm)|refseq:NP_037371.2|ensembl:ENSP00000375080 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rogid:zl5NREjuW2ahdojQSDcqWYJR92g9606 rigid:em1qIxD1gKKZmpAfQmri3XHoafk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94988-4 uniprotkb:P30153 intact:EBI-25409179 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:o949884(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym)|uniprotkb:FAM13A1_v2(isoform synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409188|imex:IM-26436-86 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94988-4(isoform-parent) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:em1qIxD1gKKZmpAfQmri3XHoafk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94988-4 uniprotkb:P67775 intact:EBI-25409179 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:o949884(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym)|uniprotkb:FAM13A1_v2(isoform synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409188|imex:IM-26436-86 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94988-4(isoform-parent) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:em1qIxD1gKKZmpAfQmri3XHoafk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94988-4 uniprotkb:Q96HN2 intact:EBI-25409179 intact:EBI-1056923|uniprotkb:O94917|uniprotkb:B4DIZ5|uniprotkb:D9N155|ensembl:ENSP00000315931 psi-mi:o949884(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym)|uniprotkb:FAM13A1_v2(isoform synonym) psi-mi:sahh3_human(display_long)|uniprotkb:AHCYL2(gene name)|psi-mi:AHCYL2(display_short)|uniprotkb:KIAA0828(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 3(gene name synonym)|uniprotkb:S-adenosylhomocysteine hydrolase-like protein 2(gene name synonym)|uniprotkb:"IP(3)Rs binding protein released with IP(3) 2"(gene name synonym)|uniprotkb:Long-IRBIT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409188|imex:IM-26436-86 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94988-4(isoform-parent) refseq:NP_001124192.1|refseq:NP_001124194.2|refseq:NP_001124195.1|refseq:NP_056143.1|ensembl:ENSG00000158467(gene)|ensembl:ENST00000325006(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0043005"(neuron projection)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|rcsb pdb:3GVP|reactome:R-HSA-425381 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rogid:OOrDmlSeGOWqnAhYQcNa4tF5pk09606 rigid:em1qIxD1gKKZmpAfQmri3XHoafk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94988-4 uniprotkb:O43865 intact:EBI-25409179 intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|uniprotkb:B4E168|ensembl:ENSP00000358814 psi-mi:o949884(display_long)|uniprotkb:FAM13A(gene name)|psi-mi:FAM13A(display_short)|uniprotkb:FAM13A1(gene name synonym)|uniprotkb:KIAA0914(gene name synonym)|uniprotkb:FAM13A1_v2(isoform synonym) psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:"IP(3)Rs binding protein released with IP(3)"(gene name synonym)|uniprotkb:IRBIT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409188|imex:IM-26436-86 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O94988-4(isoform-parent) refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|ensembl:ENSG00000168710(gene)|ensembl:ENST00000369799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Uwm2VF+xwj4Rc5+KKfgBh7l/M6I9606 rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606 rigid:em1qIxD1gKKZmpAfQmri3XHoafk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JSP0 uniprotkb:O75190 intact:EBI-4403141|uniprotkb:Q4VX84|uniprotkb:Q7Z7D9|uniprotkb:Q8N5G1|uniprotkb:F8W7P2|ensembl:ENSP00000336914|ensembl:ENSP00000364631|ensembl:ENSP00000496819 intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177 psi-mi:fgd3_human(display_long)|uniprotkb:FGD3(gene name)|psi-mi:FGD3(display_short)|uniprotkb:ZFYVE5(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 5(gene name synonym) psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409226|imex:IM-26436-198 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077005.1|refseq:NP_149077.2|refseq:NP_001273922.1|refseq:XP_016870763.1|ensembl:ENSG00000127084(gene)|ensembl:ENST00000337352(transcript)|ensembl:ENST00000375482(transcript)|ensembl:ENST00000468206(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|rcsb pdb:2COC|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:GPfnTNLHRBnUKhWFeaYG7Z6U5xA9606 rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606 rigid:Ni8bTXIesU/n/TQL+exd8G8V108 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JSP0 uniprotkb:O00148 intact:EBI-4403141|uniprotkb:Q4VX84|uniprotkb:Q7Z7D9|uniprotkb:Q8N5G1|uniprotkb:F8W7P2|ensembl:ENSP00000336914|ensembl:ENSP00000364631|ensembl:ENSP00000496819 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:fgd3_human(display_long)|uniprotkb:FGD3(gene name)|psi-mi:FGD3(display_short)|uniprotkb:ZFYVE5(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 5(gene name synonym) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409226|imex:IM-26436-198 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077005.1|refseq:NP_149077.2|refseq:NP_001273922.1|refseq:XP_016870763.1|ensembl:ENSG00000127084(gene)|ensembl:ENST00000337352(transcript)|ensembl:ENST00000375482(transcript)|ensembl:ENST00000468206(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|rcsb pdb:2COC|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:GPfnTNLHRBnUKhWFeaYG7Z6U5xA9606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 rigid:Ni8bTXIesU/n/TQL+exd8G8V108 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JSP0 uniprotkb:Q7Z5H3 intact:EBI-4403141|uniprotkb:Q4VX84|uniprotkb:Q7Z7D9|uniprotkb:Q8N5G1|uniprotkb:F8W7P2|ensembl:ENSP00000336914|ensembl:ENSP00000364631|ensembl:ENSP00000496819 intact:EBI-3866859|uniprotkb:A0AVP7|uniprotkb:A5YM75|uniprotkb:Q6ZSB0|uniprotkb:B9EGA0|uniprotkb:O00152|uniprotkb:B4DED8|uniprotkb:C9JDM2|ensembl:ENSP00000249601 psi-mi:fgd3_human(display_long)|uniprotkb:FGD3(gene name)|psi-mi:FGD3(display_short)|uniprotkb:ZFYVE5(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 5(gene name synonym) psi-mi:rhg22_human(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409226|imex:IM-26436-198 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001077005.1|refseq:NP_149077.2|refseq:NP_001273922.1|refseq:XP_016870763.1|ensembl:ENSG00000127084(gene)|ensembl:ENST00000337352(transcript)|ensembl:ENST00000375482(transcript)|ensembl:ENST00000468206(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|rcsb pdb:2COC|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_001334667.1|refseq:XP_011538306.1|refseq:NP_067049.2|refseq:NP_001242953.1|refseq:NP_001242955.1|refseq:NP_001242954.1|ensembl:ENSP00000249601|ensembl:ENST00000417247|ensembl:ENSP00000410054|ensembl:ENST00000417912|ensembl:ENSP00000412461|ensembl:ENST00000435790|ensembl:ENSP00000416701|ensembl:ENSG00000128805(gene)|ensembl:ENST00000249601(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|mint:Q7Z5H3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:GPfnTNLHRBnUKhWFeaYG7Z6U5xA9606 rogid:B6GppfBTWo7eKA5XTxP6oOG56789606 rigid:Ni8bTXIesU/n/TQL+exd8G8V108 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:P60468 intact:EBI-25409238 intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:P51571 intact:EBI-25409238 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:Q9NXS2 intact:EBI-25409238 intact:EBI-1052839|uniprotkb:Q53HE4|uniprotkb:Q96F74|ensembl:ENSP00000012049 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:qpctl_human(display_long)|uniprotkb:Golgi-resident glutaminyl-peptide cyclotransferase(gene name synonym)|uniprotkb:isoQC(gene name synonym)|uniprotkb:QPCTL(gene name)|psi-mi:QPCTL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) refseq:NP_001156849.1|refseq:NP_060129.2|ensembl:ENSG00000011478(gene)|ensembl:ENST00000012049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016603"(glutaminyl-peptide cyclotransferase activity)|go:"GO:0017186"(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)|interpro:IPR037457|interpro:IPR040234|rcsb pdb:3PB4|rcsb pdb:3PB6|rcsb pdb:3PB7|rcsb pdb:3PB8|rcsb pdb:3PB9|interpro:IPR007484(Peptidase M28) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:J4CsQuJYRh/8S2KDQQGzZh3Mra89606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:P30153 intact:EBI-25409238 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:P67775 intact:EBI-25409238 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:Q9Y3D7 intact:EBI-25409238 intact:EBI-721147|uniprotkb:Q6I9Z3|uniprotkb:Q9H5X3|ensembl:ENSP00000315693|ensembl:ENSP00000461047|ensembl:ENSP00000484240|ensembl:ENSP00000487678 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:tim16_human(display_long)|uniprotkb:Mitochondria-associated granulocyte macrophage CSF-signaling molecule(gene name synonym)|uniprotkb:PAM16(gene name)|psi-mi:PAM16(display_short)|uniprotkb:CGI-136(orf name)|uniprotkb:MAGMAS(gene name synonym)|uniprotkb:TIM16(gene name synonym)|uniprotkb:TIMM16(gene name synonym)|uniprotkb:Presequence translocated-associated motor subunit PAM16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) refseq:NP_057153.8|ensembl:ENSG00000282228(gene)|ensembl:ENST00000318059(transcript)|ensembl:ENST00000576217(transcript)|ensembl:ENST00000616009(transcript)|ensembl:ENST00000634045(transcript)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0001503"(ossification)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR005341(Protein Transporter, Pam16)|interpro:IPR036869|reactome:R-HSA-1268020|ensembl:ENSG00000217930(gene) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:k4Keu0mTFTL7XjWY9Ld9IKuJlhg9606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:Q9Y241 intact:EBI-25409238 intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:Q9NX63 intact:EBI-25409238 intact:EBI-743375|ensembl:ENSP00000262570 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) go:"GO:0008053"(mitochondrial fusion)|refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554(gene)|ensembl:ENST00000262570(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0019902"(phosphatase binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:P56385 intact:EBI-25409238 intact:EBI-2270000|uniprotkb:Q0D2L9|ensembl:ENSP00000306003 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:atp5i_human(display_long)|uniprotkb:ATP5ME(gene name)|psi-mi:ATP5ME(display_short)|uniprotkb:ATP5I(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:ATP5K(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) refseq:NP_009031.1|ensembl:ENSG00000169020(gene)|ensembl:ENST00000304312(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P56385|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:NYpqzWQYASXwSwU/BYDTMU2tJjI9606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NYF5-1 uniprotkb:O43865 intact:EBI-25409238 intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|uniprotkb:B4E168|ensembl:ENSP00000358814 psi-mi:q9nyf51(display_long)|uniprotkb:FAM13B(gene name)|psi-mi:FAM13B(display_short)|uniprotkb:C5orf5(gene name synonym)|uniprotkb:FAM13B1(gene name synonym) psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:"IP(3)Rs binding protein released with IP(3)"(gene name synonym)|uniprotkb:IRBIT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409245|imex:IM-26436-200 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9NYF5-1(isoform-parent) refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|ensembl:ENSG00000168710(gene)|ensembl:ENST00000369799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:201tmx+2Q5cdSiBvb7Q6ZXRbYZo9606 rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606 rigid:SpCFxMhmPGNqY8b1CLhHBTBGRTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZV73-1 uniprotkb:P53420 intact:EBI-25409208|ensembl:ENSP00000344446 intact:EBI-2432581|uniprotkb:A8MTZ1|uniprotkb:Q53RW9|uniprotkb:Q53S42|uniprotkb:Q53WR1|ensembl:ENSP00000379866 psi-mi:q6zv73-1(display_long)|uniprotkb:Zinc finger FYVE domain-containing protein 24(gene name synonym)|uniprotkb:FGD6(gene name)|psi-mi:FGD6(display_short)|uniprotkb:KIAA1362(gene name synonym)|uniprotkb:ZFYVE24(gene name synonym) psi-mi:co4a4_human(display_long)|uniprotkb:COL4A4(gene name)|psi-mi:COL4A4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409216|imex:IM-26436-256 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000180263(gene)|ensembl:ENST00000343958(transcript)|uniprotkb:Q6ZV73-1(isoform-parent)|intact:EBI-3959469(isoform-parent) refseq:NP_000083.3|refseq:XP_005246338.1|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8948216|ensembl:ENSG00000081052(gene)|ensembl:ENST00000396625(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|mint:P53420|rcsb pdb:5NB1|rcsb pdb:6WKU|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:tGTBRM2CAnj8C/lEzaVA7vqwRfs9606 rogid:33OBK6m4LBya+l/OQQ1JYlvFx109606 rigid:3PFvmzDjIDyHg3K5x4n1NJrL4wA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZV73-1 uniprotkb:Q5VV41 intact:EBI-25409208|ensembl:ENSP00000344446 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 psi-mi:q6zv73-1(display_long)|uniprotkb:Zinc finger FYVE domain-containing protein 24(gene name synonym)|uniprotkb:FGD6(gene name)|psi-mi:FGD6(display_short)|uniprotkb:KIAA1362(gene name synonym)|uniprotkb:ZFYVE24(gene name synonym) psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409216|imex:IM-26436-256 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000180263(gene)|ensembl:ENST00000343958(transcript)|uniprotkb:Q6ZV73-1(isoform-parent)|intact:EBI-3959469(isoform-parent) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:tGTBRM2CAnj8C/lEzaVA7vqwRfs9606 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rigid:3PFvmzDjIDyHg3K5x4n1NJrL4wA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q9UQ80 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P05109 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P04843 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P22392 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q9Y383 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q96AG4 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P48047 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P54886 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P22314 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P12270 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-1048528|uniprotkb:Q15655|uniprotkb:Q99968|uniprotkb:Q5SWY0|intact:EBI-2555905|uniprotkb:Q15624|intact:EBI-28974527|ensembl:ENSP00000356448 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:tpr_human(display_long)|uniprotkb:TPR(gene name)|psi-mi:TPR(display_short)|uniprotkb:Megator(gene name synonym)|uniprotkb:NPC-associated intranuclear protein(gene name synonym)|uniprotkb:Translocated promoter region protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSP00000356448|ensembl:ENST00000613151|ensembl:ENSP00000483425|refseq:NP_003283.2|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0006404"(RNA import into nucleus)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0010965"(regulation of mitotic sister chromatid separation)|go:"GO:0015631"(tubulin binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046832"(negative regulation of RNA export from nucleus)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR012929(Tetratricopeptide, MLP1/MLP2-like)|rcsb pdb:5TO5|rcsb pdb:5TO6|rcsb pdb:5TO7|rcsb pdb:5TVB|reactome:R-HSA-1169408|reactome:R-HSA-159227|ensembl:ENSG00000047410(gene)|ensembl:ENST00000367478(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|dip:DIP-50405N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:vgoHzJI4cSOfqPSDoy+E067AdoI9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P60174 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q08188 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-1050019|uniprotkb:A8K5N6|uniprotkb:Q32MM0|uniprotkb:O95933|uniprotkb:Q32ML9|uniprotkb:B2RCR6|uniprotkb:D3DVX1|ensembl:ENSP00000370867 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:tgm3_human(display_long)|uniprotkb:Transglutaminase-3(gene name synonym)|uniprotkb:TGM3(gene name)|psi-mi:TGM3(display_short)|uniprotkb:Transglutaminase E(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_003236.3|ensembl:ENSG00000125780(gene)|ensembl:ENST00000381458(transcript)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031424"(keratinization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043163"(cell envelope organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:Q08188|rcsb pdb:1L9M|rcsb pdb:1L9N|rcsb pdb:1NUD|rcsb pdb:1NUF|rcsb pdb:1NUG - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:5UuVUvhYOaQcLJQO2myrilPgFFw9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P37802 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-1056740|intact:EBI-2825986|uniprotkb:Q5JRQ6|uniprotkb:Q5JRQ7|uniprotkb:Q9BUH5|uniprotkb:Q9H4P0|uniprotkb:Q6FGI1|uniprotkb:E9KL39|ensembl:ENSP00000357075|ensembl:ENSP00000357077 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:tagl2_human(display_long)|uniprotkb:TAGLN2(gene name)|psi-mi:TAGLN2(display_short)|uniprotkb:KIAA0120(gene name synonym)|uniprotkb:SM22-alpha homolog(gene name synonym)|uniprotkb:CDABP0035(orf name)|uniprotkb:Epididymis tissue protein Li 7e(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_003555.1|refseq:NP_001264152.1|refseq:NP_001264153.1|ensembl:ENSG00000158710(gene)|ensembl:ENST00000320307(transcript)|ensembl:ENST00000368097(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031982"(vesicle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000557(Calponin repeat)|interpro:IPR001061("Transgelin (SM22-alpha)")|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:P37802|rcsb pdb:1WYM|reactome:R-HSA-114608 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:JxbMK5SbZWQd+XA9iYc/xuNaVQc9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P05455 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q9BRL6 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-6380719|ensembl:ENSP00000480140|uniprotkb:B2R6B8|uniprotkb:Q6PF01|uniprotkb:Q96TA3 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:srsf8_human(display_long)|uniprotkb:SRSF8(gene name)|psi-mi:SRSF8(display_short)|uniprotkb:SFRS2B(gene name synonym)|uniprotkb:SRP46(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRP46(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:XP_016872631.1|ensembl:ENSG00000263465(gene)|ensembl:ENST00000587424(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:2DNM|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_115285.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:Il/jCgENzEpp+AVMgkImR2iW3Cw9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q13243 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P34897 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q16181 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P06702 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P31151 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P62979 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P04844 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001129243.1|refseq:NP_002942.2|ensembl:ENSG00000118705(gene)|ensembl:ENST00000237530(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007568"(aging)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042493"|go:"GO:0043022"(ribosome binding)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001311234.1|refseq:NP_001311235.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P14314 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-716953|uniprotkb:Q96BU9|uniprotkb:Q96D06|uniprotkb:Q9P0W9|uniprotkb:A8K318|ensembl:ENSP00000465461 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:glu2b_human(display_long)|uniprotkb:Glucosidase II subunit beta(gene name synonym)|uniprotkb:Protein kinase C substrate 60.1 kDa protein heavy chain(gene name synonym)|uniprotkb:80K-H protein(gene name synonym)|uniprotkb:PRKCSH(gene name)|psi-mi:PRKCSH(display_short)|uniprotkb:G19P1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001001329.1|refseq:NP_002734.2|refseq:XP_011526433.1|refseq:XP_011526434.1|refseq:NP_001276031.1|ensembl:ENSG00000130175(gene)|ensembl:ENST00000589838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006491"(N-glycan processing)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028146|interpro:IPR036055|interpro:IPR036607|interpro:IPR039794|interpro:IPR044865|mint:P14314|reactome:R-HSA-381426|reactome:R-HSA-532668|reactome:R-HSA-879415|reactome:R-HSA-8957275|reactome:R-HSA-901042|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016882466.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:hs2AZthZKK6KVW8Blm1RuZVh1QM9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P30048 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P00558 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P07737 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P30101 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P22061 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-353343|uniprotkb:Q14661|uniprotkb:Q16556|uniprotkb:Q5VYC1|uniprotkb:Q5VYC2|uniprotkb:Q93061|uniprotkb:Q96II9|uniprotkb:Q99625|uniprotkb:Q9BQV7|uniprotkb:Q9BQV8|uniprotkb:Q9NP03|uniprotkb:A8K109|intact:EBI-2551555|uniprotkb:J3KP72|ensembl:ENSP00000356348|ensembl:ENSP00000420813 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:pimt_human(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short)|uniprotkb:Protein-beta-aspartate methyltransferase(gene name synonym)|uniprotkb:Protein L-isoaspartyl/D-aspartyl methyltransferase(gene name synonym)|uniprotkb:L-isoaspartyl protein carboxyl methyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001238978.1|refseq:NP_001238982.1|ensembl:ENSG00000120265(gene)|ensembl:ENST00000367378(transcript)|ensembl:ENST00000464889(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0030091"(protein repair)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|mint:P22061|rcsb pdb:1I1N|rcsb pdb:1KR5|reactome:R-HSA-5676934|refseq:NP_005380.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:wfsjVloc3sqDMXlvFAXQI6Fjilw9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P22234 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q5T653 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-3925384|uniprotkb:Q8WUL1|uniprotkb:B2RC56|uniprotkb:Q9Y311|uniprotkb:Q96Q56|ensembl:ENSP00000373404 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:rm02_human(display_long)|uniprotkb:MRPL2(gene name)|psi-mi:MRPL2(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL2m(gene name synonym)|uniprotkb:CGI-22(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001287777.1|refseq:NP_057034.2|ensembl:ENSG00000112651(gene)|ensembl:ENST00000388752(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR022666|interpro:IPR022669|mint:Q5T653|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:yg9IGILfz3U8swO+kB/kyDUoG449606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P25205 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q9UNF1 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-725832|uniprotkb:O76058|uniprotkb:Q5BJF3|uniprotkb:Q8NAL6|uniprotkb:Q9H218|uniprotkb:Q9P0U9|uniprotkb:A6NMX0|uniprotkb:Q9UM52|ensembl:ENSP00000218439|ensembl:ENSP00000364193|ensembl:ENSP00000364198|ensembl:ENSP00000364209|ensembl:ENSP00000379526 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:magd2_human(display_long)|uniprotkb:MAGE-D2 antigen(gene name synonym)|uniprotkb:Breast cancer-associated gene 1 protein(gene name synonym)|uniprotkb:11B6(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated protein JCL-1(gene name synonym)|uniprotkb:MAGED2(gene name)|psi-mi:MAGED2(display_short)|uniprotkb:BCG1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_055414.2|refseq:NP_803182.1|refseq:NP_957516.1|ensembl:ENSG00000102316(gene)|ensembl:ENST00000218439(transcript)|ensembl:ENST00000375053(transcript)|ensembl:ENST00000375058(transcript)|ensembl:ENST00000375068(transcript)|ensembl:ENST00000396224(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0016020"(membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0070294"(renal sodium ion absorption)|interpro:IPR002190(MAGE protein)|interpro:IPR028810|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9UNF1|reactome:R-HSA-114608|dip:DIP-50722N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:fXavezmKy58aGuVgzvDYjwNw3B89606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:O75427 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_002310.2|refseq:NP_001276863.1|ensembl:ENSG00000077454(gene)|ensembl:ENST00000310300(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0016605"(PML body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q96II8 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q5VUJ6 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-2659666|uniprotkb:Q9P233|uniprotkb:Q9HA88|uniprotkb:F5H2T1|uniprotkb:Q08AD5|ensembl:ENSP00000325091 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:lrch2_human(display_long)|uniprotkb:KIAA1495(gene name synonym)|uniprotkb:LRCH2(gene name)|psi-mi:LRCH2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_065922.3|refseq:NP_001230892.1|ensembl:ENSG00000130224(gene)|ensembl:ENST00000317135(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:hjJwBxAeVmoDWTtcKK5NzCIDnBo9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q9Y2L9 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-2797324|uniprotkb:Q7Z5F7|uniprotkb:Q7Z5F6|uniprotkb:Q5TBU9|uniprotkb:Q2KHR1|uniprotkb:B7ZLL5|uniprotkb:F8W6F0|uniprotkb:Q17R43|ensembl:ENSP00000374448 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:lrch1_human(display_long)|uniprotkb:CHDC1(gene name synonym)|uniprotkb:KIAA1016(gene name synonym)|uniprotkb:Calponin homology domain-containing protein 1(gene name synonym)|uniprotkb:Neuronal protein 81(gene name synonym)|uniprotkb:LRCH1(gene name)|psi-mi:LRCH1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001157685.1|refseq:NP_055931.1|refseq:NP_001157683.1|ensembl:ENSG00000136141(gene)|ensembl:ENST00000389798(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:3oNqV4dI/4ZHz1sUSsc8nmg0j049606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q03252 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-2830427|uniprotkb:O75292|uniprotkb:Q14734|uniprotkb:Q96DF6|ensembl:ENSP00000327054|intact:EBI-11044751|intact:EBI-20728818 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:lmnb2_human(display_long)|uniprotkb:LMNB2(gene name)|psi-mi:LMNB2(display_short)|uniprotkb:LMN2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000176619(gene)|ensembl:ENST00000325327(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005882"(intermediate filament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:Q03252|rcsb pdb:2LLL|rcsb pdb:5BNW|refseq:NP_116126.3|dip:DIP-57724N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:Jt7rEo5Br8HidU+VAc0L6rtBU889606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P47929 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P07195 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P00338 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:O00410 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P61604 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q96N67 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-2433703|uniprotkb:Q00M63|uniprotkb:Q2PPY7|uniprotkb:Q45RE8|uniprotkb:Q45RE9|uniprotkb:Q5T1B9|uniprotkb:Q5T1C0|uniprotkb:Q6ZV32|uniprotkb:Q8TB82|uniprotkb:Q96NG6|uniprotkb:Q9C092|intact:EBI-7303260|intact:MINT-1683616|uniprotkb:Q96NI0|intact:EBI-28980506|ensembl:ENSP00000489124 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:dock7_human(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:XP_011540628.1|refseq:NP_001258931.1|refseq:NP_212132.2|ensembl:ENST00000251157|ensembl:ENSP00000251157|ensembl:ENST00000340370|ensembl:ENSP00000340742|ensembl:ENST00000404627|ensembl:ENSP00000384446|ensembl:ENST00000454575|ensembl:ENSP00000413583|ensembl:ENST00000634264|ensembl:ENSP00000489284|ensembl:ENST00000635123|ensembl:ENSP00000489499|ensembl:ENSP00000489124|refseq:NP_001258928.1|refseq:NP_001258929.1|refseq:NP_001258930.1|refseq:NP_001317543.1|ensembl:ENSG00000116641(gene)|ensembl:ENST00000635253(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0045178"(basal part of cell)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|mint:Q96N67|rcsb pdb:6AJ4|rcsb pdb:6AJL|reactome:R-HSA-8875555|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:PHjIS0j8JJ6Il3knhzjCzMNkxKk9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P09622 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-353366|uniprotkb:Q14131|uniprotkb:Q14167|uniprotkb:Q59EV8|uniprotkb:Q8WTS4|uniprotkb:B2R5X0|ensembl:ENSP00000205402|ensembl:ENSP00000390667|uniprotkb:B4DHG0|uniprotkb:B4DT69 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:dldh_human(display_long)|uniprotkb:DLD(gene name)|psi-mi:DLD(display_short)|uniprotkb:GCSL(gene name synonym)|uniprotkb:LAD(gene name synonym)|uniprotkb:PHE3(gene name synonym)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Glycine cleavage system L protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001276679.1|refseq:NP_000099.2|rcsb pdb:6I4Z|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043544"(lipoamide binding)|ensembl:ENSG00000091140(gene)|ensembl:ENST00000205402(transcript)|ensembl:ENST00000417551(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-6783984|reactome:R-HSA-70268|reactome:R-HSA-70895|reactome:R-HSA-71064|reactome:R-HSA-71403|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:P09622|rcsb pdb:1ZMC|rcsb pdb:1ZMD|rcsb pdb:1ZY8|rcsb pdb:2F5Z|rcsb pdb:3RNM|rcsb pdb:5J5Z|rcsb pdb:5NHG|rcsb pdb:6HG8|rcsb pdb:6I4P|rcsb pdb:6I4Q|rcsb pdb:6I4R|rcsb pdb:6I4S|rcsb pdb:6I4T|rcsb pdb:6I4U|refseq:NP_001276680.1|refseq:NP_001276681.1|dip:DIP-29027N - - caution:This sequence has been withdrawn from Uniprot.|crc64:7613492C516F3835 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:7Yf9KyBWf18686aOXVUwab65rl89606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:O75390 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-487493|ensembl:ENSP00000342056|uniprotkb:Q71UT9|uniprotkb:Q7KZH0|uniprotkb:Q96FZ8|uniprotkb:Q9BWN8 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:cisy_human(display_long)|uniprotkb:CS(gene name)|psi-mi:CS(display_short)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) go:"GO:0006101"(citrate metabolic process)|refseq:NP_004068.2|ensembl:ENSG00000062485(gene)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000351328(transcript)|rcsb pdb:5UZQ|rcsb pdb:5UZR|reactome:R-HSA-1268020|reactome:R-HSA-71403|go:"GO:0070062"(extracellular exosome)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|rcsb pdb:5UZP - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:XKpnEsGOlGRNIAXMk4tTBH2okzo9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P20674 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P12277 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q05682 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:Q8WUH6 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-1042811|uniprotkb:B3KMN9|ensembl:ENSP00000280756|ensembl:ENSP00000446537|ensembl:ENSP00000446717|ensembl:ENSP00000449106|ensembl:ENSP00000449785|ensembl:ENSP00000450350 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:tm263_human(display_long)|uniprotkb:TMEM263(gene name)|psi-mi:TMEM263(display_short)|uniprotkb:C12orf23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001306590.1|refseq:NP_001306591.1|refseq:NP_001306592.1|refseq:NP_001306593.1|refseq:NP_001306595.1|refseq:NP_689474.1|ensembl:ENSG00000151135(gene)|ensembl:ENST00000280756(transcript)|ensembl:ENST00000547081(transcript)|ensembl:ENST00000547242(transcript)|ensembl:ENST00000548125(transcript)|ensembl:ENST00000550344(transcript)|ensembl:ENST00000551813(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028153 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:7ndvPlnfctdWgCYMvx/yNZ8jyQE9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P35613 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P08133 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-352541|uniprotkb:B7Z8A7|uniprotkb:E9PGK1|uniprotkb:Q6ZT79|uniprotkb:D3DQH4|ensembl:ENSP00000346550 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:anxa6_human(display_long)|uniprotkb:ANXA6(gene name)|psi-mi:ANXA6(display_short)|uniprotkb:ANX6(gene name synonym)|uniprotkb:Annexin-6(gene name synonym)|uniprotkb:Annexin VI(gene name synonym)|uniprotkb:Lipocortin VI(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:p70(gene name synonym)|uniprotkb:Protein III(gene name synonym)|uniprotkb:Chromobindin-20(gene name synonym)|uniprotkb:67 kDa calelectrin(gene name synonym)|uniprotkb:Calphobindin-II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001146.2|refseq:NP_001180473.1|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0008289"(lipid binding)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051283"(negative regulation of sequestering of calcium ion)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|ensembl:ENSG00000197043(gene)|ensembl:ENST00000354546(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003418"(growth plate cartilage chondrocyte differentiation)|interpro:IPR001464(Annexin)|interpro:IPR002393(Annexin, type VI)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:1M9I|reactome:R-HSA-445355 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:+1oKdgl2a0haedrMSJ8au35MF8c9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P08758 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P07355 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P39687 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NF50-3 uniprotkb:P24752 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-1051459|uniprotkb:B2R6H1|uniprotkb:G3XAB4|uniprotkb:Q96FG8|ensembl:ENSP00000265838 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:thil_human(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:T2(gene name synonym)|uniprotkb:ACAT1(gene name)|psi-mi:ACAT1(display_short)|uniprotkb:ACAT(gene name synonym)|uniprotkb:MAT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409278|imex:IM-26436-158 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_000010.1|ensembl:ENSG00000075239(gene)|ensembl:ENST00000265838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007420"(brain development)|go:"GO:0009725"(response to hormone)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016453"(C-acetyltransferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046356"(acetyl-CoA catabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072229"(metanephric proximal convoluted tubule development)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1902224"(ketone body metabolic process)|go:"GO:1902860"(propionyl-CoA biosynthetic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|rcsb pdb:2F2S|rcsb pdb:2IB7|rcsb pdb:2IB8|rcsb pdb:2IB9|rcsb pdb:2IBU|rcsb pdb:2IBW|rcsb pdb:2IBY|reactome:R-HSA-70895|reactome:R-HSA-77108|reactome:R-HSA-77111 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/10/21 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:UYAY+kDdcJqx/hrDFoXH9rgtm/E9606 rigid:fiBSbta+wfdd3jU38VfxfL3pP4E false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:Q8WXF1 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:P56270 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-1809742|uniprotkb:A8QJL9|uniprotkb:Q15703|uniprotkb:Q99443|uniprotkb:H3BQD6|uniprotkb:G5E927|uniprotkb:Q8NFN7|uniprotkb:C6G496|ensembl:ENSP00000313362 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:maz_human(display_long)|uniprotkb:Transcription factor Zif87(gene name synonym)|uniprotkb:Zinc finger protein 801(gene name synonym)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)|uniprotkb:Purine-binding transcription factor(gene name synonym)|uniprotkb:Pur-1(gene name synonym)|uniprotkb:ZF87(gene name synonym)|uniprotkb:ZNF801(gene name synonym)|uniprotkb:Serum amyloid A-activating factor-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_002374.2|refseq:NP_001036004.1|refseq:NP_001263205.1|refseq:NP_001263204.1|ensembl:ENSG00000103495(gene)|ensembl:ENST00000322945(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P56270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:zuCDXhF2wr8gmTyjBNse9kVUqSw9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:Q8IW93 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-7799822|ensembl:ENSP00000270747|intact:MINT-6504085|uniprotkb:Q8N244|uniprotkb:Q6PJQ4|uniprotkb:Q5TEV2|uniprotkb:A6NJ04 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:arhgj_human(display_long)|uniprotkb:Ephexin-2(gene name synonym)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:XP_011539008.1|ensembl:ENSG00000142632(gene)|ensembl:ENST00000270747(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042060"(wound healing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR036028|mint:Q8IW93|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_694945.2 - - comment:mint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:Q86XP3 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:O43670 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-2513125|ensembl:ENSP00000322777|uniprotkb:A8K6Y6|uniprotkb:Q96HW5|uniprotkb:Q9BUQ7|uniprotkb:Q53XS9|uniprotkb:E1P661|uniprotkb:E1P662|uniprotkb:E1P660 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:zn207_human(display_long)|uniprotkb:ZNF207(gene name)|psi-mi:ZNF207(display_short)|uniprotkb:BUGZ(gene name synonym)|uniprotkb:Zinc finger protein 207(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 ensembl:ENSG00000010244(gene)|ensembl:ENST00000321233(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990047"(spindle matrix)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|mint:O43670|refseq:NP_001027464.1|refseq:NP_001091977.1|refseq:NP_003448.1|refseq:XP_016880508.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:yXD8JFABrqlAoAAPPECwHsUmFNc9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:Q9BSH4 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-747797|uniprotkb:Q8N3N6|uniprotkb:Q9UI60|uniprotkb:B2RD21|ensembl:ENSP00000258975 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:taco1_human(display_long)|uniprotkb:PRO0477(orf name)|uniprotkb:TACO1(gene name)|psi-mi:TACO1(display_short)|uniprotkb:CCDC44(gene name synonym)|uniprotkb:Translational activator of mitochondrially-encoded cytochrome c oxidase I(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 44(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_057444.2|ensembl:ENSG00000136463(gene)|ensembl:ENST00000258975(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0019843"(rRNA binding)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0061743"(motor learning)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR026564|interpro:IPR029072|mint:Q9BSH4|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:c/tu89NvCs3Kt8qO8e5F6hrywBo9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:Q8IWS0 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-1055194|uniprotkb:Q5JRC8|uniprotkb:Q96JK3|uniprotkb:Q9BRU0|uniprotkb:Q5JRC7|uniprotkb:D3DTG3|uniprotkb:A8K230|uniprotkb:E9PC97|uniprotkb:B4E0G4|ensembl:ENSP00000329097|ensembl:ENSP00000359839 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:phf6_human(display_long)|uniprotkb:PHD-like zinc finger protein(gene name synonym)|uniprotkb:PHF6(gene name)|psi-mi:PHF6(display_short)|uniprotkb:KIAA1823(gene name synonym)|uniprotkb:CENP-31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_001015877.1|refseq:NP_115711.2|refseq:NP_115834.1|ensembl:ENSG00000156531(gene)|ensembl:ENST00000332070(transcript)|ensembl:ENST00000370803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015631"(tubulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|mint:Q8IWS0|rcsb pdb:4NN2|rcsb pdb:4R7A|go:"GO:0005730"(nucleolus) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:ZHj/64dPBMmA7GOgpdtHLxeNOu49606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:Q9Y383 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:P00367 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865|uniprotkb:B3KV55|uniprotkb:B4DGN5 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 ensembl:ENSG00000148672(gene)|ensembl:ENST00000277865(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042802"(identical protein binding)|refseq:NP_005262.1|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|reactome:R-HSA-2151201|reactome:R-HSA-8964539 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:P48730 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-751621|uniprotkb:Q96KZ6|uniprotkb:Q9BTN5|uniprotkb:A2I2P2|ensembl:ENSP00000324464 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:kc1d_human(display_long)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_001884.2|refseq:NP_620693.1|dip:DIP-39735N|ensembl:ENSG00000141551(gene)|ensembl:ENST00000314028(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48730|rcsb pdb:3UYS|rcsb pdb:3UYT|rcsb pdb:3UZP|rcsb pdb:4HGT|rcsb pdb:4HNF|rcsb pdb:4KB8|rcsb pdb:4KBA|rcsb pdb:4KBC|rcsb pdb:4KBK|rcsb pdb:4TN6|rcsb pdb:4TW9|rcsb pdb:4TWC|rcsb pdb:5IH4|rcsb pdb:5IH5|rcsb pdb:5IH6|rcsb pdb:5MQV|rcsb pdb:5OKT|rcsb pdb:5W4W|rcsb pdb:6F1W|rcsb pdb:6F26|rcsb pdb:6GZM|rcsb pdb:6HMP|rcsb pdb:6HMR|rcsb pdb:6PXN|rcsb pdb:6PXO|rcsb pdb:6PXP|rcsb pdb:6RCG|rcsb pdb:6RCH|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-204005|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-400253|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:Rz5aON17Bfduv29izmgHa/FR1/49606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:P62633 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-1047529|uniprotkb:D3DNB9|uniprotkb:D3DNC0|uniprotkb:D3DNC1|uniprotkb:P20694|uniprotkb:Q5QJR0|uniprotkb:Q6PJI7|uniprotkb:Q96NV3|uniprotkb:B4DP17|uniprotkb:Q4JGY1|uniprotkb:B2RAV9|uniprotkb:Q4JGY0|uniprotkb:Q5U0E9|ensembl:ENSP00000410619|uniprotkb:A8K7V4|uniprotkb:E9PDR7 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:cnbp_human(display_long)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:CNBP(gene name)|psi-mi:CNBP(display_short)|uniprotkb:ZNF9(gene name synonym)|uniprotkb:RNF163(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_001120664.1|refseq:NP_001120668.1|refseq:NP_003409.1|refseq:NP_001120665.1|refseq:NP_001120666.1|ensembl:ENSG00000169714(gene)|ensembl:ENST00000422453(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P62633|refseq:NP_001120667.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:x5yqfxy/s3fE/6EmvjrEe7PmanQ9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:Q07065 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:P50750 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5FWK3 uniprotkb:Q9BU76 intact:EBI-17170552|ensembl:ENSMUSP00000088105|ensembl:ENSMUSP00000106961|ensembl:ENSMUSP00000106962|uniprotkb:Q8C3X5|uniprotkb:Q923D8 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:rhg01_mouse(display_long)|uniprotkb:Arhgap1(gene name)|psi-mi:Arhgap1(display_short)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409394|imex:IM-26436-118 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027247(gene)|ensembl:ENSMUST00000090614(transcript)|ensembl:ENSMUST00000111329(transcript)|ensembl:ENSMUST00000111330(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031252"(cell leading edge)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|go:"GO:0017124"(SH3 domain binding)|refseq:NP_001139374.1|refseq:NP_666236.3|refseq:XP_006499307.1|refseq:XP_006499308.1|refseq:XP_006499309.1|refseq:XP_006499310.1|refseq:XP_006499311.1|refseq:XP_006499312.1|refseq:XP_006499313.1|refseq:XP_011237759.1 refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:67eIwLOXHf4xfa/KTTKxN0spCkk10090 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rigid:MdcwXM5JOb2vaVpbzIwRTWAKQ2c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:O43324 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-1048486|uniprotkb:Q5THS2|ensembl:ENSP00000369038|uniprotkb:C9JLK5 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:mca3_human(display_long)|uniprotkb:Multisynthase complex auxiliary component p18(gene name synonym)|uniprotkb:Elongation factor p18(gene name synonym)|uniprotkb:EEF1E1(gene name)|psi-mi:EEF1E1(display_short)|uniprotkb:P18(gene name synonym)|uniprotkb:AIMP3(gene name synonym)|uniprotkb:Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001129122.1|refseq:NP_004271.1|ensembl:ENSG00000124802(gene)|ensembl:ENST00000379715(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036282|interpro:IPR042450|mint:O43324|rcsb pdb:2UZ8|go:"GO:0043065"(positive regulation of apoptotic process)|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5BMU|rcsb pdb:5Y6L|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-50581N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:4AuJouC9q6uAH/4EH8SKSPHyEZU9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:Q10570 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:P31944 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:Q9HB71 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-1047302|uniprotkb:O60666|ensembl:ENSP00000356652|uniprotkb:B2ZWH2|uniprotkb:Q5R371|uniprotkb:B3KSF1|uniprotkb:Q5R370 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:cybp_human(display_long)|uniprotkb:Siah-interacting protein(gene name synonym)|uniprotkb:S100A6-binding protein(gene name synonym)|uniprotkb:CACYBP(gene name)|psi-mi:CACYBP(display_short)|uniprotkb:S100A6BP(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:PNAS-107(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR015120(Siah interacting protein, N terminal)|interpro:IPR037201|interpro:IPR037893|mint:Q9HB71|rcsb pdb:1X5M|rcsb pdb:2A25|rcsb pdb:2A26|go:"GO:0071277"(cellular response to calcium ion)|refseq:NP_001007215.1|refseq:NP_055227.1|ensembl:ENSG00000116161(gene)|ensembl:ENST00000367679(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0015631"(tubulin binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|refseq:XP_016856535.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:mvv1o19mLHBS3FDnATyOFsDoZvk9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:Q13523 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:O00410 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:Q6UN15 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:Q9Y285 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_004452.1|ensembl:ENSG00000179115(gene)|ensembl:ENST00000314606(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|dip:DIP-53610N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:P35520 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:Q13555 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-1383465|uniprotkb:O00561|uniprotkb:Q5SWX4|uniprotkb:Q8NIA4|uniprotkb:O15378|uniprotkb:Q13556|uniprotkb:Q5SQZ3|uniprotkb:Q5SQZ4|uniprotkb:Q8N4I3|uniprotkb:Q13279|uniprotkb:Q13282|uniprotkb:Q7KYX5|uniprotkb:A0A0A0MS52|uniprotkb:A0A0A0MT11 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:kcc2g_human(display_long)|uniprotkb:CAMK(gene name synonym)|uniprotkb:CAMK-II(gene name synonym)|uniprotkb:CAMK2G(gene name)|psi-mi:CAMK2G(display_short)|uniprotkb:CAMKG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001213.2|refseq:NP_751909.1|refseq:NP_751913.1|refseq:XP_005270260.1|refseq:NP_001307827.1|refseq:NP_001191421.1|dip:DIP-51315N|mint:Q13555|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014733"(regulation of skeletal muscle adaptation)|go:"GO:0016020"(membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:2UX0|rcsb pdb:2V7O|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442729|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:qtCEps5UkV7tprB2QmjCDK5YyIo9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:Q13557 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-351018|intact:EBI-1642546|uniprotkb:Q52PK4|uniprotkb:Q59G21|uniprotkb:Q8N553|uniprotkb:Q9UGH6|uniprotkb:Q9UQE9|uniprotkb:A8MVS8|ensembl:ENSP00000339740|ensembl:ENSP00000507073 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:kcc2d_human(display_long)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)|uniprotkb:CAMKD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001212.2|refseq:NP_742112.1|refseq:NP_742113.1|refseq:NP_742125.1|refseq:NP_742126.1|refseq:NP_742127.1|refseq:NP_001308495.1|refseq:NP_001308502.1|refseq:NP_001308509.1|refseq:NP_001308518.1|ensembl:ENSG00000145349(gene)|ensembl:ENST00000342666(transcript)|ensembl:ENST00000683023(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031432"(titin binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901725"(regulation of histone deacetylase activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13557|rcsb pdb:2VN9|rcsb pdb:2W2C|rcsb pdb:2WEL|rcsb pdb:3GP2|rcsb pdb:5VLO|rcsb pdb:6AYW|reactome:R-HSA-111932|reactome:R-HSA-3371571|reactome:R-HSA-399719|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-5673000|reactome:R-HSA-5673001|reactome:R-HSA-6802946|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-877300|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|interpro:IPR032710|refseq:XP_011530591.1|refseq:XP_011530593.1|dip:DIP-33129N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q52LW3 uniprotkb:Q9UII2 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203|ensembl:ENSP00000494248 psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:"Inhibitor of F(1)F(o)-ATPase"(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409428|imex:IM-26436-308 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770(gene)|ensembl:ENSG00000285390(gene)|ensembl:ENST00000335514(transcript)|ensembl:ENST00000647074(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043532"(angiostatin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0140260"(mitochondrial proton-transporting ATP synthase complex binding)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|go:"GO:0051346"(negative regulation of hydrolase activity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606 rigid:2ENGqaZ26Qy6vkSUqsHWHH4ugiw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q68EM7-2 uniprotkb:Q9BPW8 intact:EBI-3957963|ensembl:ENSP00000303130|ensembl:ENSP00000500849 intact:EBI-307125|uniprotkb:O43800|uniprotkb:B2RAY3|ensembl:ENSP00000216121 psi-mi:q68em7-2(display_long)|uniprotkb:ARHGAP17(gene name)|psi-mi:ARHGAP17(display_short)|uniprotkb:RICH1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 17(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 1(gene name synonym)|uniprotkb:MSTP066(orf name)|uniprotkb:MSTP110(orf name) psi-mi:nips1_human(display_long)|uniprotkb:NIPSNAP1(gene name)|psi-mi:NIPSNAP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409472|imex:IM-26436-160 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642807(isoform-parent)|uniprotkb:Q68EM7-2(isoform-parent)|ensembl:ENSG00000140750(gene)|ensembl:ENSG00000288353(gene)|ensembl:ENST00000303665(transcript)|ensembl:ENST00000673196(transcript) refseq:NP_001189431.1|refseq:NP_003625.2|ensembl:ENSG00000184117(gene)|ensembl:ENST00000216121(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:Q9BPW8 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:nC1rvE2a2rdv25O/dZfIjEenKEA9606 rogid:mOosuRNhEeYvVB5cUbkMzTJ7X7s9606 rigid:wKGxh/3HuT2rhT1ZsreLwH5rSVo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q68EM7-2 uniprotkb:Q9Y5K6 intact:EBI-3957963|ensembl:ENSP00000303130|ensembl:ENSP00000500849 intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264 psi-mi:q68em7-2(display_long)|uniprotkb:ARHGAP17(gene name)|psi-mi:ARHGAP17(display_short)|uniprotkb:RICH1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 17(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 1(gene name synonym)|uniprotkb:MSTP066(orf name)|uniprotkb:MSTP110(orf name) psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409472|imex:IM-26436-160 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642807(isoform-parent)|uniprotkb:Q68EM7-2(isoform-parent)|ensembl:ENSG00000140750(gene)|ensembl:ENSG00000288353(gene)|ensembl:ENST00000303665(transcript)|ensembl:ENST00000673196(transcript) ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:nC1rvE2a2rdv25O/dZfIjEenKEA9606 rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606 rigid:wKGxh/3HuT2rhT1ZsreLwH5rSVo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z628-2 uniprotkb:Q5TCQ9 intact:EBI-21531888 intact:EBI-310506|uniprotkb:Q5TCR0|uniprotkb:Q9H2V6|uniprotkb:Q5TCQ8|uniprotkb:Q9H5Y8|uniprotkb:Q9HBC4|intact:EBI-2512710|intact:EBI-991068|ensembl:ENSP00000304604|uniprotkb:Q9HCD8|uniprotkb:A0A024R0E9|uniprotkb:A0A024R0H3 psi-mi:q7z6282(display_long)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:ARHGEF8(gene name synonym) psi-mi:magi3_human(display_long)|uniprotkb:MAGI3(gene name)|psi-mi:MAGI3(display_short)|uniprotkb:KIAA1634(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409458|imex:IM-26436-120 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7Z628-2(isoform-parent) ensembl:ENST00000307546(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|ensembl:ENSG00000081026(gene)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030054"(cell junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0016020"(membrane)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030035|interpro:IPR036020|interpro:IPR036034|mint:Q5TCQ9|rcsb pdb:3SOE|refseq:NP_001136254.1|refseq:NP_690864.2|refseq:XP_005270794.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TRUc4m1yvF8jqTRUxW77h6W+Wdk9606 rogid:muK+zH3ww4Ve8aJ74iU2be8hRa09606 rigid:mMJMl/UyFtJ56FivncEtdfXLCDw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z628-2 uniprotkb:Q96QZ7 intact:EBI-21531888 intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188 psi-mi:q7z6282(display_long)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:ARHGEF8(gene name synonym) psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409458|imex:IM-26436-120 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7Z628-2(isoform-parent) refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR030033|interpro:IPR027417|refseq:XP_005265621.1|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071944"(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TRUc4m1yvF8jqTRUxW77h6W+Wdk9606 rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606 rigid:mMJMl/UyFtJ56FivncEtdfXLCDw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z628-2 uniprotkb:Q9H583 intact:EBI-21531888 intact:EBI-1048716|uniprotkb:Q5T3Q8|uniprotkb:Q6P197|uniprotkb:Q9NW23|ensembl:ENSP00000355541 psi-mi:q7z6282(display_long)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:ARHGEF8(gene name synonym) psi-mi:heat1_human(display_long)|uniprotkb:Protein BAP28(gene name synonym)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)|uniprotkb:BAP28(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 10 homolog(gene name synonym)|uniprotkb:UTP10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409458|imex:IM-26436-120 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7Z628-2(isoform-parent) refseq:NP_060542.4|ensembl:ENSG00000119285(gene)|ensembl:ENST00000366582(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022125|interpro:IPR040191|mint:Q9H583|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TRUc4m1yvF8jqTRUxW77h6W+Wdk9606 rogid:0WoP84UUVfXWppmvCYa/n5GTzc89606 rigid:mMJMl/UyFtJ56FivncEtdfXLCDw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z628-2 uniprotkb:Q12959 intact:EBI-21531888 intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21 psi-mi:q7z6282(display_long)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:ARHGEF8(gene name synonym) psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409458|imex:IM-26436-120 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q7Z628-2(isoform-parent) reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TRUc4m1yvF8jqTRUxW77h6W+Wdk9606 rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606 rigid:mMJMl/UyFtJ56FivncEtdfXLCDw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q96TA2 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV8|uniprotkb:D3DRV9|uniprotkb:B4DNM1|intact:EBI-10989776|ensembl:ENSP00000318480 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_647473.1|refseq:NP_055078.1|refseq:NP_001240795.1|ensembl:ENSG00000136758(gene)|ensembl:ENST00000326799(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q9C0J8 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-712637|uniprotkb:Q6NUQ0|uniprotkb:Q587J1|uniprotkb:Q05DP8|uniprotkb:Q53FG9|uniprotkb:Q9NUL1|uniprotkb:Q69YF7|ensembl:ENSP00000325377 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:wdr33_human(display_long)|uniprotkb:WDR33(gene name)|psi-mi:WDR33(display_short)|uniprotkb:WDC146(gene name synonym)|uniprotkb:WD repeat-containing protein 33(gene name synonym)|uniprotkb:WD repeat-containing protein of 146 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:XP_011509738.1|refseq:NP_001006623.1|refseq:NP_060853.3|refseq:NP_001006624.1|ensembl:ENSG00000136709(gene)|ensembl:ENST00000322313(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005581"(collagen trimer)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006301"(postreplication repair)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007283"(spermatogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9C0J8|rcsb pdb:6BLY|rcsb pdb:6BM0|rcsb pdb:6DNH|rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:FzGeASJyKaYaqFQfFBYby692REg9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q9NYU2 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:O94842 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q3ZCQ8 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q6I9Y2 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-716286|uniprotkb:Q6P1L3|uniprotkb:Q8WUF2|uniprotkb:Q9H5H0|ensembl:ENSP00000295899 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:thoc7_human(display_long)|uniprotkb:Functional spliceosome-associated protein 24(gene name synonym)|uniprotkb:hTREX30(gene name synonym)|uniprotkb:NIF3L1BP1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym)|uniprotkb:THOC7(gene name)|psi-mi:THOC7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001272333.1|refseq:NP_079351.2|ensembl:ENSG00000163634(gene)|ensembl:ENST00000295899(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q6I9Y2|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:15M7nouxNuzlKZPawajrahz0LAY9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q13769 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-5280316|uniprotkb:O60839|uniprotkb:Q9UPZ5|ensembl:ENSP00000380969|ensembl:ENSP00000380970|ensembl:ENSP00000380971|ensembl:ENSP00000420306 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:thoc5_human(display_long)|uniprotkb:THOC5(gene name)|psi-mi:THOC5(display_short)|uniprotkb:C22orf19(gene name synonym)|uniprotkb:KIAA0983(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 79(gene name synonym)|uniprotkb:NF2/meningioma region protein pK1.3(gene name synonym)|uniprotkb:Placental protein 39.2(gene name synonym)|uniprotkb:hTREX90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001002877.1|refseq:NP_001002878.1|refseq:NP_001002879.1|refseq:NP_003669.4|ensembl:ENSG00000100296(gene)|ensembl:ENST00000397871(transcript)|ensembl:ENST00000397872(transcript)|ensembl:ENST00000397873(transcript)|ensembl:ENST00000490103(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR019163|mint:Q13769|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:JoeUa2WhtV/dR2HSjUEBAHDZZtw9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:P31948 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q9P035 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:P49721 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q9H0G5 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-5464397|uniprotkb:Q6FI71|ensembl:ENSP00000247026 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:nsrp1_human(display_long)|uniprotkb:NSRP1(gene name)|psi-mi:NSRP1(display_short)|uniprotkb:CCDC55(gene name synonym)|uniprotkb:NSRP70(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 55(gene name synonym)|uniprotkb:Nuclear speckle-related protein 70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_115517.1|refseq:NP_001248396.1|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032502"(developmental process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018612|interpro:IPR042816|mint:Q9H0G5|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000126653(gene)|ensembl:ENST00000247026(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:Hp8MjUsGzGZWl+Y/zyzkOxjnLc49606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q13015 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-6269719|ensembl:ENSP00000357917 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:P55081 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-1048159|uniprotkb:Q86TG6|ensembl:ENSP00000267812 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:mfap1_human(display_long)|uniprotkb:Spliceosome B complex protein MFAP1(gene name synonym)|uniprotkb:MFAP1(gene name)|psi-mi:MFAP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_005917.2|ensembl:ENSG00000140259(gene)|ensembl:ENST00000267812(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001527"(microfibril)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005813"(centrosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR009730(Micro-fibrillar-associated 1, C-terminal)|interpro:IPR033194|mint:P55081|rcsb pdb:5F5S|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-2129379 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:38SGUW2hc2ZwbmyTO52uGQRw79U9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q69YN4 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:JXKhohRVBiT4P++8+/edtkir+h89606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:O94992 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q9HC38 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-1049764|uniprotkb:Q96B89|uniprotkb:Q9H3J8|uniprotkb:Q9HC37|uniprotkb:Q9NVN1|uniprotkb:D3DTG9|uniprotkb:D3DTH1|ensembl:ENSP00000301328 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:glod4_human(display_long)|uniprotkb:GLOD4(gene name)|psi-mi:GLOD4(display_short)|uniprotkb:C17orf25(gene name synonym)|uniprotkb:CGI-150(orf name)|uniprotkb:My027(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_057164.3|ensembl:ENSG00000167699(gene)|ensembl:ENST00000301328(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR029068|interpro:IPR037523|interpro:IPR043193|mint:Q9HC38|rcsb pdb:3ZI1|interpro:IPR043194 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:0Xu9EPSkmX9t8j0yLaCyBLhKcUs9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q6UN15 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q9UBS4 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q86XP3 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:O60563 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:Q8IVM0 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-723996|intact:EBI-28978624|ensembl:ENSP00000376250|uniprotkb:Q86VH7 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:ccd50_human(display_long)|uniprotkb:Protein Ymer(gene name synonym)|uniprotkb:CCDC50(gene name)|psi-mi:CCDC50(display_short)|uniprotkb:C3orf6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_777568.1|refseq:NP_848018.1|ensembl:ENSG00000152492(gene)|ensembl:ENST00000392456(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR029311|interpro:IPR039303|rcsb pdb:6LAN|ensembl:ENST00000392455|ensembl:ENSP00000376249|ensembl:ENSP00000376250 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:KXHuNkpMuvUCHFpMGG8D6kPUrgQ9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:O43852 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60992 uniprotkb:P00918 intact:EBI-643726|uniprotkb:A2AH49|ensembl:ENSMUSP00000062782 intact:EBI-724062|ensembl:ENSP00000285379|uniprotkb:Q6FI12|uniprotkb:Q96ET9|uniprotkb:B2R7G8 psi-mi:vav2_mouse(display_long)|uniprotkb:Vav2(gene name)|psi-mi:Vav2(display_short) psi-mi:cah2_human(display_long)|uniprotkb:Carbonic anhydrase II(gene name synonym)|uniprotkb:Carbonate dehydratase II(gene name synonym)|uniprotkb:Carbonic anhydrase C(gene name synonym)|uniprotkb:CA2(gene name)|psi-mi:CA2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409482|imex:IM-26436-202 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033526.1|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR022613|interpro:IPR035732|interpro:IPR035733|interpro:IPR035880|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q60992|reactome:R-MMU-114604|reactome:R-MMU-193648|reactome:R-MMU-2029482|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-3928665|reactome:R-MMU-416482|reactome:R-MMU-4420097|reactome:R-MMU-445144|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|interpro:IPR000980(SH2 motif)|ensembl:ENSMUSG00000009621(gene)|ensembl:ENSMUST00000056176(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_000058.1|rcsb pdb:5YUI|rcsb pdb:5YUJ|rcsb pdb:5U0G|rcsb pdb:5YUK|rcsb pdb:5ZXW|rcsb pdb:6B4D|rcsb pdb:6B59|rcsb pdb:5ULN|rcsb pdb:6B5A|rcsb pdb:6BBS|rcsb pdb:6BC9|rcsb pdb:6BCC|rcsb pdb:6C7W|rcsb pdb:6C7X|rcsb pdb:6CA2|rcsb pdb:6CEH|rcsb pdb:6CJV|rcsb pdb:6D1L|rcsb pdb:6D1M|rcsb pdb:5UMC|rcsb pdb:5VGY|rcsb pdb:6E8P|rcsb pdb:6E8X|rcsb pdb:6E91|rcsb pdb:6E92|rcsb pdb:6EBE|rcsb pdb:6ECZ|rcsb pdb:6EDA|rcsb pdb:6EEA|rcsb pdb:6EEH|rcsb pdb:6EEO|rcsb pdb:6EQU|rcsb pdb:5W8B|rcsb pdb:6FJI|rcsb pdb:5WEX|rcsb pdb:6FJJ|rcsb pdb:6G3Q|rcsb pdb:6G6T|rcsb pdb:6GCY|rcsb pdb:6GDC|rcsb pdb:6GM9|rcsb pdb:5WG7|rcsb pdb:5WGP|rcsb pdb:5WLR|rcsb pdb:6GOT|rcsb pdb:6GXB|rcsb pdb:5WLT|rcsb pdb:5WLU|rcsb pdb:5WLV|rcsb pdb:5Y2R|rcsb pdb:5Y2S|rcsb pdb:6GXE|rcsb pdb:6H29|rcsb pdb:6H2Z|rcsb pdb:6H33|rcsb pdb:6H34|rcsb pdb:6H3Q|rcsb pdb:6H6S|rcsb pdb:6HD2|rcsb pdb:1BV3|rcsb pdb:1CA2|rcsb pdb:1CA3|rcsb pdb:1CAH|rcsb pdb:1CAI|rcsb pdb:1CAJ|rcsb pdb:1CAK|rcsb pdb:1CAL|rcsb pdb:1CAM|rcsb pdb:1CAN|rcsb pdb:1CAO|rcsb pdb:1CAY|rcsb pdb:1CAZ|rcsb pdb:1CCS|rcsb pdb:1CCT|rcsb pdb:1CCU|rcsb pdb:1CIL|rcsb pdb:1CIM|rcsb pdb:1CIN|rcsb pdb:1CNB|rcsb pdb:1CNC|rcsb pdb:1CNG|rcsb pdb:1CNH|rcsb pdb:1CNI|rcsb pdb:1CNJ|rcsb pdb:1BNW|rcsb pdb:1CNK|rcsb pdb:1CNW|rcsb pdb:1CNX|rcsb pdb:1CNY|rcsb pdb:1CRA|rcsb pdb:1CVA|rcsb pdb:1CVB|rcsb pdb:1IF4|rcsb pdb:1IF5|rcsb pdb:1IF6|rcsb pdb:1IF7|rcsb pdb:1IF8|rcsb pdb:1IF9|rcsb pdb:1KWQ|rcsb pdb:1I9Q|rcsb pdb:1KWR|rcsb pdb:1LG5|rcsb pdb:1LG6|rcsb pdb:1LGD|rcsb pdb:1LUG|rcsb pdb:1LZV|rcsb pdb:1MOO|rcsb pdb:1MUA|rcsb pdb:1OKL|rcsb pdb:1OKM|rcsb pdb:1OKN|rcsb pdb:1OQ5|rcsb pdb:1RAY|rcsb pdb:1RAZ|rcsb pdb:1RZA|rcsb pdb:1RZB|rcsb pdb:1RZC|rcsb pdb:1RZD|rcsb pdb:1RZE|rcsb pdb:1T9N|rcsb pdb:1TB0|rcsb pdb:1TBT|rcsb pdb:1TE3|rcsb pdb:1TEQ|rcsb pdb:1TEU|rcsb pdb:6HR3|rcsb pdb:6HX5|rcsb pdb:6HXD|rcsb pdb:6HZX|rcsb pdb:6I0W|rcsb pdb:6I1U|rcsb pdb:6I2F|rcsb pdb:6I3E|rcsb pdb:6IC2|rcsb pdb:6KLZ|rcsb pdb:6KM0|rcsb pdb:6KM1|rcsb pdb:6KM2|rcsb pdb:6KM3|rcsb pdb:6KM4|rcsb pdb:6KM5|rcsb pdb:6KM6|rcsb pdb:6LUU|rcsb pdb:6LUV|rcsb pdb:6LUW|rcsb pdb:6LUX|rcsb pdb:6LUY|rcsb pdb:6LUZ|rcsb pdb:6LV1|rcsb pdb:6LV2|rcsb pdb:6LV3|rcsb pdb:6LV4|rcsb pdb:6LV5|rcsb pdb:6LV6|rcsb pdb:6LV7|rcsb pdb:6LV8|rcsb pdb:6LV9|rcsb pdb:6HQX|rcsb pdb:6LVA|rcsb pdb:6MBV|rcsb pdb:6MBY|rcsb pdb:6NLV|rcsb pdb:6NM0|rcsb pdb:6ODZ|rcsb pdb:6OE0|rcsb pdb:6OE1|rcsb pdb:6OTI|rcsb pdb:6OTK|rcsb pdb:6OTM|rcsb pdb:6OTO|rcsb pdb:6OTP|rcsb pdb:6OTQ|rcsb pdb:1CVC|rcsb pdb:1CVD|rcsb pdb:1CVE|rcsb pdb:1G46|rcsb pdb:1G48|rcsb pdb:1CVF|rcsb pdb:1CVH|rcsb pdb:1DCA|rcsb pdb:1DCB|rcsb pdb:1EOU|rcsb pdb:1F2W|rcsb pdb:1FQL|rcsb pdb:1FQM|rcsb pdb:1FQN|rcsb pdb:1FQR|rcsb pdb:1FR4|rcsb pdb:1FR7|rcsb pdb:1FSN|rcsb pdb:1FSQ|rcsb pdb:1FSR|rcsb pdb:1G0E|rcsb pdb:1G0F|rcsb pdb:1G1D|rcsb pdb:1G3Z|rcsb pdb:1G45|rcsb pdb:6OUD|rcsb pdb:6OUE|rcsb pdb:6OUF|rcsb pdb:6OUH|rcsb pdb:6OUI|rcsb pdb:6OUJ|rcsb pdb:6OUK|rcsb pdb:6OUM|rcsb pdb:6PDV|rcsb pdb:6PEA|rcsb pdb:6PGX|rcsb pdb:6Q3O|rcsb pdb:6Q9T|rcsb pdb:6QEB|rcsb pdb:6QL1|rcsb pdb:6QL2|rcsb pdb:6QL3|rcsb pdb:6OUB|rcsb pdb:6R6F|rcsb pdb:6R6J|rcsb pdb:6RFH|rcsb pdb:6RG3|rcsb pdb:6RG4|rcsb pdb:6RG5|rcsb pdb:6RH4|rcsb pdb:6RHJ|rcsb pdb:6RHK|rcsb pdb:6RIG|rcsb pdb:6RIT|rcsb pdb:6RJJ|rcsb pdb:6RKN|rcsb pdb:6RL9|rcsb pdb:6RM1|rcsb pdb:6RMP|rcsb pdb:6RMX|rcsb pdb:6RMY|rcsb pdb:6RNP|rcsb pdb:6ROB|rcsb pdb:6ROE|rcsb pdb:6ROF|rcsb pdb:3TVO|rcsb pdb:3U3A|rcsb pdb:3U45|rcsb pdb:3U47|rcsb pdb:3U7C|rcsb pdb:3V2J|rcsb pdb:3TVN|rcsb pdb:3V2M|rcsb pdb:3V3F|rcsb pdb:3V3G|rcsb pdb:3V3H|rcsb pdb:3V3I|rcsb pdb:3V3J|rcsb pdb:3V5G|rcsb pdb:3V7X|rcsb pdb:3VBD|rcsb pdb:3ZP9|rcsb pdb:4BCW|rcsb pdb:4BF1|rcsb pdb:4BF6|rcsb pdb:4CA2|rcsb pdb:4CAC|rcsb pdb:4CQ0|rcsb pdb:4DZ7|rcsb pdb:4DZ9|rcsb pdb:4E3D|rcsb pdb:6RQI|rcsb pdb:6T5C|rcsb pdb:6T7U|rcsb pdb:6T81|rcsb pdb:6T9Z|rcsb pdb:6U4Q|rcsb pdb:6U4T|rcsb pdb:6UFB|rcsb pdb:6UFC|rcsb pdb:6UFD|rcsb pdb:6UGN|rcsb pdb:6UGO|rcsb pdb:6UGP|rcsb pdb:6UGQ|rcsb pdb:6UGR|rcsb pdb:6UGZ|rcsb pdb:6UH0|rcsb pdb:6UX1|rcsb pdb:6UZU|rcsb pdb:6VJ3|rcsb pdb:6VKG|rcsb pdb:1TG3|rcsb pdb:1TG9|rcsb pdb:1TH9|rcsb pdb:1THK|rcsb pdb:1TTM|rcsb pdb:1UGA|rcsb pdb:1UGB|rcsb pdb:1UGC|rcsb pdb:1UGD|rcsb pdb:1UGE|rcsb pdb:1UGF|rcsb pdb:1UGG|rcsb pdb:1XEG|rcsb pdb:1XEV|rcsb pdb:1XPZ|rcsb pdb:1XQ0|rcsb pdb:1YDA|rcsb pdb:1YDB|rcsb pdb:1YDC|rcsb pdb:1YDD|rcsb pdb:1YO0|rcsb pdb:1YO1|rcsb pdb:1YO2|rcsb pdb:1Z9Y|rcsb pdb:1ZE8|rcsb pdb:1ZFK|rcsb pdb:1ZFQ|rcsb pdb:1ZGE|rcsb pdb:4E3F|rcsb pdb:4E3G|rcsb pdb:4E3H|rcsb pdb:4E49|rcsb pdb:4E4A|rcsb pdb:4E5Q|rcsb pdb:4FIK|rcsb pdb:4FL7|rcsb pdb:4FPT|rcsb pdb:4FRC|rcsb pdb:4FU5|rcsb pdb:4FVN|rcsb pdb:4FVO|rcsb pdb:4G0C|rcsb pdb:4GL1|rcsb pdb:4HBA|rcsb pdb:4HEW|rcsb pdb:4HEY|rcsb pdb:4HEZ|rcsb pdb:4HF3|rcsb pdb:4HT0|rcsb pdb:4IDR|rcsb pdb:4ILX|rcsb pdb:4ITO|rcsb pdb:4ITP|rcsb pdb:4IWZ|rcsb pdb:4JS6|rcsb pdb:4JSA|rcsb pdb:4JSS|rcsb pdb:4JSW|rcsb pdb:4JSZ|rcsb pdb:4K0S|rcsb pdb:4K0T|rcsb pdb:4K0Z|rcsb pdb:4K13|rcsb pdb:4K1Q|rcsb pdb:4KAP|rcsb pdb:4KNI|rcsb pdb:4KNJ|rcsb pdb:4KUV|rcsb pdb:4KUW|rcsb pdb:4KUY|rcsb pdb:4KV0|rcsb pdb:4L5U|rcsb pdb:4L5V|rcsb pdb:4L5W|rcsb pdb:4LHI|rcsb pdb:4LP6|rcsb pdb:4M2R|rcsb pdb:4M2U|rcsb pdb:4M2V|rcsb pdb:4M2W|rcsb pdb:4MDG|rcsb pdb:4MDL|rcsb pdb:4MDM|rcsb pdb:4MLT|rcsb pdb:4MLX|rcsb pdb:1ZGF|rcsb pdb:1ZH9|rcsb pdb:1ZSA|rcsb pdb:1ZSB|rcsb pdb:1ZSC|rcsb pdb:2ABE|rcsb pdb:2AW1|rcsb pdb:2AX2|rcsb pdb:2CA2|rcsb pdb:2CBA|rcsb pdb:2CBB|rcsb pdb:2CBC|rcsb pdb:2CBD|rcsb pdb:2CBE|rcsb pdb:2EU2|rcsb pdb:2EU3|rcsb pdb:2EZ7|rcsb pdb:2F14|rcsb pdb:2FMG|rcsb pdb:2FMZ|rcsb pdb:2FNK|rcsb pdb:2FNM|rcsb pdb:2FNN|rcsb pdb:2HOC|rcsb pdb:2FOQ|rcsb pdb:2FOS|rcsb pdb:2ILI|rcsb pdb:2FOU|rcsb pdb:2NNG|rcsb pdb:2NNO|rcsb pdb:2NNS|rcsb pdb:2FOV|rcsb pdb:2GD8|rcsb pdb:2GEH|rcsb pdb:2NNV|rcsb pdb:2NWO|rcsb pdb:2NWP|rcsb pdb:2NWY|rcsb pdb:2NWZ|rcsb pdb:2H15|rcsb pdb:2NXR|rcsb pdb:2NXS|rcsb pdb:2NXT|rcsb pdb:2O4Z|rcsb pdb:2OSF|rcsb pdb:2OSM|rcsb pdb:2POU|rcsb pdb:2POV|rcsb pdb:2POW|rcsb pdb:2H4N|rcsb pdb:2Q1B|rcsb pdb:2Q1Q|rcsb pdb:2Q38|rcsb pdb:2QO8|rcsb pdb:2QOA|rcsb pdb:2QP6|rcsb pdb:2VVA|rcsb pdb:2VVB|rcsb pdb:2HD6|rcsb pdb:2HKK|rcsb pdb:2WD2|rcsb pdb:2WD3|rcsb pdb:2HL4|rcsb pdb:2HNC|rcsb pdb:2WEG|rcsb pdb:2WEH|rcsb pdb:2WEJ|rcsb pdb:2WEO|rcsb pdb:4MTY|rcsb pdb:4N0X|rcsb pdb:4N16|rcsb pdb:4PQ7|rcsb pdb:4PXX|rcsb pdb:4PYX|rcsb pdb:4PYY|rcsb pdb:4PZH|rcsb pdb:4Q06|rcsb pdb:4Q07|rcsb pdb:4Q08|rcsb pdb:4Q09|rcsb pdb:4Q49|rcsb pdb:4Q6D|rcsb pdb:4Q6E|rcsb pdb:4Q78|rcsb pdb:4Q7P|rcsb pdb:4Q7S|rcsb pdb:4Q7V|rcsb pdb:4Q7W|rcsb pdb:4Q81|rcsb pdb:4Q83|rcsb pdb:4Q87|rcsb pdb:4Q8X|rcsb pdb:4Q8Y|rcsb pdb:4Q8Z|rcsb pdb:4Q90|rcsb pdb:4Q99|rcsb pdb:4Q9Y|rcsb pdb:4QEF|rcsb pdb:4QIY|rcsb pdb:4QJM|rcsb pdb:4QK1|rcsb pdb:4QK2|rcsb pdb:4QK3|rcsb pdb:4QSA|rcsb pdb:4QSB|rcsb pdb:4QSI|rcsb pdb:4QTL|rcsb pdb:4QY3|rcsb pdb:4R59|rcsb pdb:4R5A|rcsb pdb:4R5B|rcsb pdb:4RFC|rcsb pdb:4RFD|rcsb pdb:4RH2|rcsb pdb:4RIU|rcsb pdb:4RIV|rcsb pdb:4RN4|rcsb pdb:4RUX|rcsb pdb:4RUY|rcsb pdb:4RUZ|rcsb pdb:4WL4|rcsb pdb:4WW6|rcsb pdb:4MO8|rcsb pdb:4XE1|rcsb pdb:4Y0J|rcsb pdb:4YGJ|rcsb pdb:4YGK|rcsb pdb:4YGL|rcsb pdb:4YGN|rcsb pdb:4YVY|rcsb pdb:4YWP|rcsb pdb:4YX4|rcsb pdb:4YXI|rcsb pdb:4YXO|rcsb pdb:6RRI|rcsb pdb:6RS5|rcsb pdb:6RSZ|rcsb pdb:6RVF|rcsb pdb:6RVK|rcsb pdb:6RVL|rcsb pdb:6RW1|rcsb pdb:6RZX|rcsb pdb:6S03|rcsb pdb:6S9G|rcsb pdb:6S9Z|rcsb pdb:6SAC|rcsb pdb:6SAS|rcsb pdb:6SAY|rcsb pdb:6SB7|rcsb pdb:6SBH|rcsb pdb:6SBL|rcsb pdb:6SBM|rcsb pdb:6SD7|rcsb pdb:6SDH|rcsb pdb:6SDI|rcsb pdb:6SDJ|rcsb pdb:6SDL|rcsb pdb:6SDS|rcsb pdb:6SEY|rcsb pdb:6RRG|rcsb pdb:6SFQ|rcsb pdb:6SFU|rcsb pdb:6SG0|rcsb pdb:6SG6|rcsb pdb:6SX9|rcsb pdb:6SYB|rcsb pdb:6SYS|rcsb pdb:6T4N|rcsb pdb:6T4O|rcsb pdb:6T4P|rcsb pdb:2X7S|rcsb pdb:2X7T|rcsb pdb:2X7U|rcsb pdb:3B4F|rcsb pdb:3BET|rcsb pdb:3BL0|rcsb pdb:3BL1|rcsb pdb:3C7P|rcsb pdb:3CA2|rcsb pdb:3CAJ|rcsb pdb:3CYU|rcsb pdb:3D8W|rcsb pdb:3D92|rcsb pdb:3D93|rcsb pdb:3D9Z|rcsb pdb:3DAZ|rcsb pdb:3DBU|rcsb pdb:3DC3|rcsb pdb:3DC9|rcsb pdb:3DCC|rcsb pdb:3DCS|rcsb pdb:3DCW|rcsb pdb:3DD0|rcsb pdb:3DD8|rcsb pdb:3DV7|rcsb pdb:3DVB|rcsb pdb:3DVC|rcsb pdb:3DVD|rcsb pdb:3EFI|rcsb pdb:3EFT|rcsb pdb:4YYT|rcsb pdb:4Z0Q|rcsb pdb:4Z1E|rcsb pdb:4Z1J|rcsb pdb:4Z1K|rcsb pdb:4Z1N|rcsb pdb:4ZAO|rcsb pdb:4ZWI|rcsb pdb:4ZWX|rcsb pdb:4ZWY|rcsb pdb:4ZWZ|rcsb pdb:4ZX0|rcsb pdb:4ZX1|rcsb pdb:5A6H|rcsb pdb:5AMD|rcsb pdb:5AMG|rcsb pdb:5AML|rcsb pdb:5BNL|rcsb pdb:5BRU|rcsb pdb:5BRV|rcsb pdb:5BRW|rcsb pdb:5BYI|rcsb pdb:5C8I|rcsb pdb:5CA2|rcsb pdb:5CAC|rcsb pdb:5CLU|rcsb pdb:5DOG|rcsb pdb:5DOH|rcsb pdb:5DRS|rcsb pdb:5DSK|rcsb pdb:5DSL|rcsb pdb:5DSM|rcsb pdb:5DSO|rcsb pdb:5DSP|rcsb pdb:4YXU|rcsb pdb:5DSQ|rcsb pdb:5DSR|rcsb pdb:5E28|rcsb pdb:5E2K|rcsb pdb:5E2R|rcsb pdb:5E2S|rcsb pdb:5EH5|rcsb pdb:5EH7|rcsb pdb:5EH8|rcsb pdb:5EHE|rcsb pdb:5EHV|rcsb pdb:5EHW|rcsb pdb:5EIJ|rcsb pdb:5EKH|rcsb pdb:3F4X|rcsb pdb:3F8E|rcsb pdb:3FFP|rcsb pdb:3GZ0|rcsb pdb:3HFP|rcsb pdb:3HKN|rcsb pdb:3HKQ|rcsb pdb:3HKT|rcsb pdb:3HKU|rcsb pdb:3HLJ|rcsb pdb:3HS4|rcsb pdb:3IBI|rcsb pdb:3IBL|rcsb pdb:3IBN|rcsb pdb:3IBU|rcsb pdb:3IEO|rcsb pdb:3IGP|rcsb pdb:3K2F|rcsb pdb:3K34|rcsb pdb:3K7K|rcsb pdb:3KIG|rcsb pdb:3KKX|rcsb pdb:3KNE|rcsb pdb:3KOI|rcsb pdb:3KOK|rcsb pdb:3KON|rcsb pdb:3KS3|rcsb pdb:3KWA|rcsb pdb:3L14|rcsb pdb:3M04|rcsb pdb:3M14|rcsb pdb:3M1J|rcsb pdb:3M1K|rcsb pdb:3M1Q|rcsb pdb:3M1W|rcsb pdb:3M2N|rcsb pdb:3M2X|rcsb pdb:3M2Y|rcsb pdb:3M2Z|rcsb pdb:3M3X|rcsb pdb:3M40|rcsb pdb:3M5E|rcsb pdb:3M5S|rcsb pdb:3M5T|rcsb pdb:3M67|rcsb pdb:3M96|rcsb pdb:3M98|rcsb pdb:3MHC|rcsb pdb:3MHI|rcsb pdb:3MHL|rcsb pdb:3MHM|rcsb pdb:3MHO|rcsb pdb:3ML2|rcsb pdb:3MMF|rcsb pdb:3MNA|rcsb pdb:3MNH|rcsb pdb:3MNI|rcsb pdb:3MNJ|rcsb pdb:3MNK|rcsb pdb:3MNU|rcsb pdb:3MWO|rcsb pdb:3MYQ|rcsb pdb:3MZC|rcsb pdb:3N0N|rcsb pdb:3N2P|rcsb pdb:5EKM|rcsb pdb:5EOI|rcsb pdb:5FDC|rcsb pdb:5FDI|rcsb pdb:5FLO|rcsb pdb:5FLP|rcsb pdb:5FLQ|rcsb pdb:5FLR|rcsb pdb:5FLS|rcsb pdb:5FLT|rcsb pdb:5FNG|rcsb pdb:5FNH|rcsb pdb:5FNI|rcsb pdb:5FNJ|rcsb pdb:5FNK|rcsb pdb:5FNL|rcsb pdb:5FNM|rcsb pdb:5G01|rcsb pdb:5G03|rcsb pdb:5G0B|rcsb pdb:5G0C|rcsb pdb:5GMN|rcsb pdb:5J8Z|rcsb pdb:5EKJ|rcsb pdb:3N4B|rcsb pdb:3N3J|rcsb pdb:3NB5|rcsb pdb:3NI5|rcsb pdb:3NJ9|rcsb pdb:3OIK|rcsb pdb:3OIL|rcsb pdb:3OIM|rcsb pdb:3OKU|rcsb pdb:3OKV|rcsb pdb:3OY0|rcsb pdb:3OYQ|rcsb pdb:3OYS|rcsb pdb:3P3H|rcsb pdb:3P3J|rcsb pdb:3P44|rcsb pdb:3P4V|rcsb pdb:3P55|rcsb pdb:3P58|rcsb pdb:3P5A|rcsb pdb:3P5L|rcsb pdb:3PJJ|rcsb pdb:3PO6|rcsb pdb:5JE7|rcsb pdb:5JEG|rcsb pdb:5JEH|rcsb pdb:5JEP|rcsb pdb:5JES|rcsb pdb:5JG3|rcsb pdb:5JG5|rcsb pdb:5JGS|rcsb pdb:5JGT|rcsb pdb:5JMZ|rcsb pdb:5JN3|rcsb pdb:5JN7|rcsb pdb:5JQ0|rcsb pdb:5JQT|rcsb pdb:5L3O|rcsb pdb:5L6K|rcsb pdb:5L6T|rcsb pdb:5L70|rcsb pdb:5L9E|rcsb pdb:5JDV|rcsb pdb:5LJQ|rcsb pdb:5LJT|rcsb pdb:5LL4|rcsb pdb:5LL8|rcsb pdb:5LLC|rcsb pdb:5LLE|rcsb pdb:5LLG|rcsb pdb:5LLH|rcsb pdb:5LMD|rcsb pdb:5LVS|rcsb pdb:5M78|rcsb pdb:5MJN|rcsb pdb:5N0D|rcsb pdb:5N0E|rcsb pdb:5N1R|rcsb pdb:5N1S|rcsb pdb:5N24|rcsb pdb:5N25|rcsb pdb:5NEA|rcsb pdb:5NEE|rcsb pdb:5NXG|ensembl:ENSG00000104267(gene)|ensembl:ENST00000285379(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004064"(arylesterase activity)|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016836"(hydro-lyase activity)|go:"GO:0030424"(axon)|go:"GO:0032849"(positive regulation of cellular pH reduction)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043627"(response to estrogen)|go:"GO:0044070"(regulation of anion transport)|rcsb pdb:1G4O|rcsb pdb:1G52|rcsb pdb:1G53|rcsb pdb:1G54|rcsb pdb:1H4N|rcsb pdb:1H9N|rcsb pdb:1H9Q|rcsb pdb:1HCA|rcsb pdb:1G4J|rcsb pdb:1HEA|rcsb pdb:1HEB|rcsb pdb:1HEC|rcsb pdb:1HED|rcsb pdb:1HVA|rcsb pdb:1I8Z|rcsb pdb:1I90|rcsb pdb:1I91|rcsb pdb:1I9L|rcsb pdb:1I9M|rcsb pdb:1I9N|rcsb pdb:1I9O|rcsb pdb:1I9P|rcsb pdb:3QYK|rcsb pdb:3R16|rcsb pdb:3R17|rcsb pdb:3RG3|rcsb pdb:3RG4|rcsb pdb:3RGE|rcsb pdb:3RJ7|rcsb pdb:3RLD|rcsb pdb:3RYJ|rcsb pdb:3RYV|rcsb pdb:3RYX|rcsb pdb:3RYY|rcsb pdb:3RYZ|rcsb pdb:3RZ0|rcsb pdb:3RZ1|rcsb pdb:3PYK|rcsb pdb:3RZ5|rcsb pdb:3RZ7|rcsb pdb:3RZ8|rcsb pdb:3S71|rcsb pdb:3S72|rcsb pdb:3S73|rcsb pdb:3S74|rcsb pdb:3S75|rcsb pdb:3S76|rcsb pdb:3S77|rcsb pdb:3S78|rcsb pdb:3S8X|rcsb pdb:3S9T|rcsb pdb:3SAP|rcsb pdb:3SAX|rcsb pdb:3SBH|rcsb pdb:3SBI|rcsb pdb:3T5U|rcsb pdb:3T5Z|rcsb pdb:3T82|rcsb pdb:3T83|rcsb pdb:3T84|rcsb pdb:3T85|rcsb pdb:3TMJ|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR023561|interpro:IPR036398|mint:P00918|rcsb pdb:12CA|rcsb pdb:1A42|rcsb pdb:1AM6|rcsb pdb:1AVN|rcsb pdb:1BCD|rcsb pdb:1BIC|rcsb pdb:1BN1|rcsb pdb:1BN3|rcsb pdb:1BN4|rcsb pdb:1BNM|rcsb pdb:1BNN|rcsb pdb:1BNQ|rcsb pdb:1BNT|rcsb pdb:1BNU|rcsb pdb:1BNV|rcsb pdb:5NXI|rcsb pdb:5NY3|rcsb pdb:5NY6|rcsb pdb:5NYA|rcsb pdb:5O07|rcsb pdb:5OGN|rcsb pdb:5OGO|rcsb pdb:5OGP|rcsb pdb:5SZ0|rcsb pdb:5SZ1|rcsb pdb:5SZ2|rcsb pdb:5NXM|rcsb pdb:5NXO|rcsb pdb:5SZ3|rcsb pdb:5SZ4|rcsb pdb:5SZ5|rcsb pdb:5SZ6|rcsb pdb:5NXP|rcsb pdb:5SZ7|rcsb pdb:5T71|rcsb pdb:5T72|rcsb pdb:5T74|rcsb pdb:5T75|rcsb pdb:5TFX|rcsb pdb:5TH4|rcsb pdb:5THI|rcsb pdb:5THJ|rcsb pdb:5THN|rcsb pdb:5TI0|rcsb pdb:5TXY|rcsb pdb:5TY1|rcsb pdb:5TY8|rcsb pdb:5TY9|rcsb pdb:5NXV|rcsb pdb:5NXW|rcsb pdb:5NY1|rcsb pdb:5TYA|rcsb pdb:5U0D|rcsb pdb:5U0E|rcsb pdb:5U0F|rcsb pdb:6WKA|rcsb pdb:6WQ4|rcsb pdb:6WQ5|rcsb pdb:6WQ7|rcsb pdb:6WQ8|rcsb pdb:6WQ9|rcsb pdb:6XVH|rcsb pdb:6XWZ|rcsb pdb:6XXT|rcsb pdb:6YH4|rcsb pdb:6YH5|rcsb pdb:6YH6|rcsb pdb:6YH7|rcsb pdb:6YH8|rcsb pdb:6YH9|rcsb pdb:6YHA|rcsb pdb:6YHB|rcsb pdb:6YHC|rcsb pdb:6YJ3|rcsb pdb:6YKC|rcsb pdb:6YKH|rcsb pdb:6YMA|rcsb pdb:6YMB|rcsb pdb:6YO2|rcsb pdb:6YO4|rcsb pdb:6YO7|rcsb pdb:6YOI|rcsb pdb:6YOK|rcsb pdb:6YOL|rcsb pdb:6YPW|rcsb pdb:6YQT|rcsb pdb:6YQU|rcsb pdb:6YRI|rcsb pdb:6YZJ|rcsb pdb:6YZK|rcsb pdb:6YZL|rcsb pdb:6YZT|rcsb pdb:6YZU|rcsb pdb:6YZV|rcsb pdb:6YZM|rcsb pdb:6YZW|rcsb pdb:6YZX|rcsb pdb:6Z04|rcsb pdb:6ZR8|rcsb pdb:6YZN|rcsb pdb:6YZO|rcsb pdb:7BI5|rcsb pdb:7CA2|rcsb pdb:7JNR|rcsb pdb:7JNV|rcsb pdb:7JNW|rcsb pdb:7JNX|rcsb pdb:7JNZ|rcsb pdb:7JO0|rcsb pdb:7JO1|rcsb pdb:7JO2|rcsb pdb:7JO3|rcsb pdb:7JOB|rcsb pdb:7JOC|rcsb pdb:7K6I|rcsb pdb:7K6J|rcsb pdb:7K6K|rcsb pdb:7K6L|rcsb pdb:7K6T|rcsb pdb:7K6U|rcsb pdb:7K6X|rcsb pdb:7K6Z|rcsb pdb:8CA2|rcsb pdb:9CA2|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-1475029|rcsb pdb:6YZP|rcsb pdb:6YZQ|rcsb pdb:6YZR|rcsb pdb:6YZS - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PYI5dXgxDpwXCc7HMwQFN4H15Zs10090 rogid:Er5rv/L2XS7uyrm/fPxFFsN+EsU9606 rigid:11/Nv9mvW/1VwlvP+viHciL3g3I false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43307-1 uniprotkb:Q96RY5 intact:EBI-25399711|ensembl:ENSP00000253401|ensembl:ENSP00000500829 intact:EBI-7128475|ensembl:ENSP00000293925|ensembl:ENSP00000380559|uniprotkb:Q9P2C1|uniprotkb:B1AJY1|uniprotkb:A8MZL1|uniprotkb:Q8NDN1|intact:MINT-1370680 psi-mi:o43307-1(display_long)|uniprotkb:Collybistin(gene name synonym)|uniprotkb:PEM-2 homolog(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 9(gene name synonym)|uniprotkb:"CB3(SH3+)"(isoform synonym)|uniprotkb:ARHGEF9(gene name)|psi-mi:ARHGEF9(display_short)|uniprotkb:ARHDH9(gene name synonym)|uniprotkb:KIAA0424(gene name synonym) psi-mi:crml_human(display_long)|uniprotkb:CRAMP1(gene name)|psi-mi:CRAMP1(display_short)|uniprotkb:C16orf34(gene name synonym)|uniprotkb:CRAMP1L(gene name synonym)|uniprotkb:Cramped chromatin regulator homolog 1(gene name synonym)|uniprotkb:HN1L(gene name synonym)|uniprotkb:Hematological and neurological expressed 1-like protein(gene name synonym)|uniprotkb:KIAA1426(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409609|imex:IM-26436-164 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131089(gene)|ensembl:ENST00000253401(transcript)|ensembl:ENST00000671907(transcript)|intact:EBI-3447299(isoform-parent) interpro:IPR017884|ensembl:ENSG00000007545(gene)|ensembl:ENST00000293925(transcript)|ensembl:ENST00000397412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007389"(pattern specification process)|interpro:IPR001005(SANT, DNA-binding)|refseq:NP_065876.3 - - comment:mint|comment:homomint figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fNeHhwbyPWGv+2Iak2k7AE/gDd49606 rogid:480K9t0nkljILuwAdKb0QjaedB09606 rigid:MnxT+olxpR6G6m1jifqh1xCd8B4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43307-1 uniprotkb:P28074 intact:EBI-25399711|ensembl:ENSP00000253401|ensembl:ENSP00000500829 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:o43307-1(display_long)|uniprotkb:Collybistin(gene name synonym)|uniprotkb:PEM-2 homolog(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 9(gene name synonym)|uniprotkb:"CB3(SH3+)"(isoform synonym)|uniprotkb:ARHGEF9(gene name)|psi-mi:ARHGEF9(display_short)|uniprotkb:ARHDH9(gene name synonym)|uniprotkb:KIAA0424(gene name synonym) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409609|imex:IM-26436-164 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131089(gene)|ensembl:ENST00000253401(transcript)|ensembl:ENST00000671907(transcript)|intact:EBI-3447299(isoform-parent) refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fNeHhwbyPWGv+2Iak2k7AE/gDd49606 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:MnxT+olxpR6G6m1jifqh1xCd8B4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43307-1 uniprotkb:Q9NQX3 intact:EBI-25399711|ensembl:ENSP00000253401|ensembl:ENSP00000500829 intact:EBI-2371891|uniprotkb:Q9H4E9|uniprotkb:Q9P2G2|uniprotkb:Q96KU4|ensembl:ENSP00000312771 psi-mi:o43307-1(display_long)|uniprotkb:Collybistin(gene name synonym)|uniprotkb:PEM-2 homolog(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 9(gene name synonym)|uniprotkb:"CB3(SH3+)"(isoform synonym)|uniprotkb:ARHGEF9(gene name)|psi-mi:ARHGEF9(display_short)|uniprotkb:ARHDH9(gene name synonym)|uniprotkb:KIAA0424(gene name synonym) psi-mi:geph_human(display_long)|uniprotkb:GPHN(gene name)|psi-mi:GPHN(display_short)|uniprotkb:GPH(gene name synonym)|uniprotkb:KIAA1385(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409609|imex:IM-26436-164 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131089(gene)|ensembl:ENST00000253401(transcript)|ensembl:ENST00000671907(transcript)|intact:EBI-3447299(isoform-parent) refseq:NP_001019389.1|refseq:NP_065857.1|dip:DIP-41076N|rcsb pdb:1JLJ|reactome:R-HSA-947581|interpro:IPR038987|ensembl:ENSG00000171723(gene)|ensembl:ENST00000315266(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0010038"(response to metal ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018315"(molybdenum incorporation into molybdenum-molybdopterin complex)|go:"GO:0030425"(dendrite)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0061598"(molybdopterin adenylyltransferase activity)|go:"GO:0061599"(molybdopterin molybdotransferase activity)|go:"GO:0072579"(glycine receptor clustering)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0099144"(anchored component of synaptic membrane)|go:"GO:0099572"(postsynaptic specialization)|go:"GO:0099634"(postsynaptic specialization membrane)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR008284(Molybdenum cofactor biosynthesis, conserved site)|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fNeHhwbyPWGv+2Iak2k7AE/gDd49606 rogid:iu4Nl7g9dOChbmYok/lo6kjW3pM9606 rigid:MnxT+olxpR6G6m1jifqh1xCd8B4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43307-1 uniprotkb:Q9H3G5 intact:EBI-25399711|ensembl:ENSP00000253401|ensembl:ENSP00000500829 intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4 psi-mi:o43307-1(display_long)|uniprotkb:Collybistin(gene name synonym)|uniprotkb:PEM-2 homolog(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 9(gene name synonym)|uniprotkb:"CB3(SH3+)"(isoform synonym)|uniprotkb:ARHGEF9(gene name)|psi-mi:ARHGEF9(display_short)|uniprotkb:ARHDH9(gene name synonym)|uniprotkb:KIAA0424(gene name synonym) psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409609|imex:IM-26436-164 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131089(gene)|ensembl:ENST00000253401(transcript)|ensembl:ENST00000671907(transcript)|intact:EBI-3447299(isoform-parent) ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fNeHhwbyPWGv+2Iak2k7AE/gDd49606 rogid:antgab61u6D+KmbopQeowXqSqWQ9606 rigid:MnxT+olxpR6G6m1jifqh1xCd8B4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:Q9H936 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-1050588|uniprotkb:Q8TBU8|uniprotkb:A8K366|uniprotkb:C9J1H6|uniprotkb:E9PJD3|uniprotkb:E9PKB2|uniprotkb:E9PL68|uniprotkb:E9PN26|uniprotkb:E9PNQ3|uniprotkb:E9PP01|uniprotkb:E9PR97|ensembl:ENSP00000322020|ensembl:ENSP00000437236|ensembl:ENSP00000486058 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:ghc1_human(display_long)|uniprotkb:"Glutamate/H(+) symporter 1"(gene name synonym)|uniprotkb:Solute carrier family 25 member 22(gene name synonym)|uniprotkb:SLC25A22(gene name)|psi-mi:SLC25A22(display_short)|uniprotkb:GC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_001177989.1|refseq:NP_001177990.1|refseq:NP_078974.1|ensembl:ENSG00000177542(gene)|ensembl:ENST00000320230(transcript)|ensembl:ENST00000531214(transcript)|ensembl:ENST00000628067(transcript)|go:"GO:0005280"("amino acid:proton symporter activity")|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-HSA-428643|refseq:XP_011518671.1|refseq:XP_011518672.1|refseq:XP_011518673.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:B1e6uu3Vx73qy/JrHS7p63p0QMM9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P32119 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:O43347 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-726515|uniprotkb:Q96PU0|uniprotkb:Q96PU1|uniprotkb:Q96PU2|uniprotkb:Q96PU3|intact:EBI-28986772|ensembl:ENSP00000257552 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:msi1h_human(display_long)|uniprotkb:MSI1(gene name)|psi-mi:MSI1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_002433.1|ensembl:ENSP00000257552|refseq:XP_011536663.1|ensembl:ENSG00000135097(gene)|ensembl:ENST00000257552(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0007399"(nervous system development)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|reactome:R-HSA-9010553 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:41/VCaTWDXjzXSisiAoG19FFVF09606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:Q9UGP4 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-2652871|uniprotkb:Q17RQ1|uniprotkb:Q9BQQ9|uniprotkb:Q9NQ47|ensembl:ENSP00000273317 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:limd1_human(display_long)|uniprotkb:LIMD1(gene name)|psi-mi:LIMD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_055055.1|ensembl:ENSG00000144791(gene)|ensembl:ENST00000273317(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016310"(phosphorylation)|go:"GO:0016442"(RISC complex)|go:"GO:0016477"(cell migration)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028734|reactome:R-HSA-1234176 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:Eq6aJ83PR4G/LIlUi5H2Bv31sTQ9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P84077 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:zray9asm6VonxpuJpv0dRBspPt89606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P04350 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:Q9Y490 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-2462036|uniprotkb:A6NMY0|uniprotkb:Q86YD0|uniprotkb:Q9NZQ2|uniprotkb:Q9UHH8|uniprotkb:Q9UPX3|intact:EBI-28967697|ensembl:ENSP00000316029 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:tln1_human(display_long)|uniprotkb:TLN1(gene name)|psi-mi:TLN1(display_short)|uniprotkb:KIAA1027(gene name synonym)|uniprotkb:TLN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 ensembl:ENSP00000316029|refseq:NP_006280.3|ensembl:ENSG00000137076(gene)|ensembl:ENST00000314888(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y490|rcsb pdb:1SYQ|rcsb pdb:2MWN|rcsb pdb:4DJ9|rcsb pdb:6R9T|reactome:R-HSA-114608|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381038|reactome:R-HSA-399955|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:C7FGaR2291KB6hBSloee5L8lYgA9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:O14925 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-1047996|uniprotkb:Q53FF8|uniprotkb:Q6P5S5|uniprotkb:Q5T1E6|ensembl:ENSP00000464522 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:tim23_human(display_long)|uniprotkb:TIMM23(gene name)|psi-mi:TIMM23(display_short)|uniprotkb:TIM23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_006318.1|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005681(Mitochondrial import inner membrane translocase, subunit Tim23)|mint:O14925|reactome:R-HSA-1268020|ensembl:ENSG00000265354(gene)|ensembl:ENST00000580018(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:Hmu/kwfaPLGFGYBJH0oue7JDYqM9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P30048 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P30405 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-5544229|uniprotkb:Q2YDB7|uniprotkb:Q5W131|ensembl:ENSP00000225174 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:ppif_human(display_long)|uniprotkb:PPIF(gene name)|psi-mi:PPIF(display_short)|uniprotkb:CYP3(gene name synonym)|uniprotkb:Cyclophilin F(gene name synonym)|uniprotkb:Rotamase F(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Mitochondrial cyclophilin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_005720.1|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010849"(regulation of proton-transporting ATPase activity, rotational mechanism)|go:"GO:0010939"(regulation of necrotic cell death)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0070266"(necroptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:1902445"(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:"GO:1902686"(mitochondrial outer membrane permeabilization involved in programmed cell death)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P30405|rcsb pdb:2BIT|rcsb pdb:2BIU|rcsb pdb:2Z6W|rcsb pdb:3QYU|rcsb pdb:3R49|rcsb pdb:3R4G|rcsb pdb:3R54|rcsb pdb:3R56|rcsb pdb:3R57|rcsb pdb:3R59|rcsb pdb:3RCF|rcsb pdb:3RCG|rcsb pdb:3RCI|rcsb pdb:3RCK|rcsb pdb:3RCL|rcsb pdb:3RD9|rcsb pdb:3RDA|rcsb pdb:3RDB|rcsb pdb:3RDC|rcsb pdb:4J58|rcsb pdb:4J59|rcsb pdb:4J5A|rcsb pdb:4J5B|rcsb pdb:4J5C|rcsb pdb:4J5D|rcsb pdb:4J5E|rcsb pdb:4O8H|rcsb pdb:4O8I|rcsb pdb:4XNC|rcsb pdb:4ZSC|rcsb pdb:4ZSD|rcsb pdb:5A0E|rcsb pdb:5CBT|rcsb pdb:5CBU|rcsb pdb:5CBV|rcsb pdb:5CBW|rcsb pdb:5CCN|rcsb pdb:5CCQ|rcsb pdb:5CCR|rcsb pdb:5CCS|rcsb pdb:6R8L|rcsb pdb:6R8O|rcsb pdb:6R8W|rcsb pdb:6R9S|rcsb pdb:6R9U|rcsb pdb:6R9X|rcsb pdb:6RA1|rcsb pdb:6Y3E|rcsb pdb:6YBM|ensembl:ENSG00000108179(gene)|ensembl:ENST00000225174(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0002931"(response to ischemia)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:5sa9mIaCM/Fo9PA4NgA1p4c4WIg9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P12004 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:Q7Z7H8 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-723524|ensembl:ENSP00000324100|uniprotkb:Q96B80|uniprotkb:Q96Q55|uniprotkb:A6NGJ4 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:rm10_human(display_long)|uniprotkb:MRPL8(gene name synonym)|uniprotkb:RPML8(gene name synonym)|uniprotkb:39S ribosomal protein L8, mitochondrial(gene name synonym)|uniprotkb:MRPL10(gene name)|psi-mi:MRPL10(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL10m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_660298.2|ensembl:ENSG00000159111(gene)|ensembl:ENST00000351111(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR043141|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7A5I|refseq:NP_683685.1|dip:DIP-59717N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:596vwngTyHb2gmaS48VUilgPQtw9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:Q6IAN0 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-725639|uniprotkb:B5MEF4|uniprotkb:Q6UX59|uniprotkb:Q9BTF9|uniprotkb:Q9UFM6|uniprotkb:Q9Y3A1|ensembl:ENSP00000378887 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:drs7b_human(display_long)|uniprotkb:DHRS7B(gene name)|psi-mi:DHRS7B(display_short)|uniprotkb:SDR32C1(gene name synonym)|uniprotkb:Short-chain dehydrogenase/reductase family 32C member 1(gene name synonym)|uniprotkb:CGI-93(orf name)|uniprotkb:UNQ212/PRO238(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_056325.2|ensembl:ENSG00000109016(gene)|ensembl:ENST00000395511(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|reactome:R-HSA-75896|refseq:NP_001317088.1|refseq:XP_016879915.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:qGu2N6bspgbSJE+AIL0Xeh6b0J49606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P04080 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-1051966|ensembl:ENSP00000291568 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:cytb_human(display_long)|uniprotkb:Stefin-B(gene name synonym)|uniprotkb:Liver thiol proteinase inhibitor(gene name synonym)|uniprotkb:CPI-B(gene name synonym)|uniprotkb:CSTB(gene name)|psi-mi:CSTB(display_short)|uniprotkb:CST6(gene name synonym)|uniprotkb:STFB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_000091.1|ensembl:ENSG00000160213(gene)|ensembl:ENST00000291568(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|interpro:IPR018073|mint:P04080|rcsb pdb:1STF|rcsb pdb:2OCT|rcsb pdb:4N6V|reactome:R-HSA-6798695 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:KwR0XgOq6SeHdqxriNE8xIUMmUo9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P36542 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P40616 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-1052746|uniprotkb:P80417|uniprotkb:Q53XB1|uniprotkb:B4DWW1|ensembl:ENSP00000261636|intact:EBI-11157530 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:arl1_human(display_long)|uniprotkb:ARL1(gene name)|psi-mi:ARL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 refseq:NP_001168.1|ensembl:ENSG00000120805(gene)|ensembl:ENST00000261636(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009404"(toxin metabolic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40616|rcsb pdb:1UPT|rcsb pdb:4DCN|rcsb pdb:5EE5|rcsb pdb:5J5C|reactome:R-HSA-6811440|interpro:IPR005225(Small GTP-binding protein) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:4sRUSYrH1mt5ol85HlMNSEn1j9M9606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q2M1Z3 uniprotkb:P18085 intact:EBI-2803146|uniprotkb:Q9ULL6|intact:EBI-28967829|ensembl:ENSP00000264245 intact:EBI-1237085|ensembl:ENSP00000306010|uniprotkb:P21371|uniprotkb:B2R7J7 psi-mi:rhg31_human(display_long)|uniprotkb:CDGAP(gene name synonym)|uniprotkb:KIAA1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP31(gene name)|psi-mi:ARHGAP31(display_short) psi-mi:arf4_human(display_long)|uniprotkb:ARF4(gene name)|psi-mi:ARF4(display_short)|uniprotkb:ARF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409534|imex:IM-26436-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264245|refseq:NP_065805.2|reactome:R-HSA-9013149|ensembl:ENSG00000031081(gene)|ensembl:ENST00000264245(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|mint:Q2M1Z3|reactome:R-HSA-8980692|reactome:R-HSA-9013148 ensembl:ENSG00000168374(gene)|ensembl:ENST00000303436(transcript)|refseq:NP_001651.1|dip:DIP-38214N|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0060271"(cilium assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P18085|rcsb pdb:1Z6X|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:O2R7XelJ27j5lnUlzZX4ax1TUHo9606 rogid:AN3aBuSStAMrmkqq1HEDQtOiCy49606 rigid:7EvTt6ZPEfVrQyPFIiBC2gV4V1M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A0S2Z547 uniprotkb:Q9Y2Z0 intact:EBI-25409574 intact:EBI-307008|ensembl:ENSP00000367208|uniprotkb:Q5JAK5|uniprotkb:Q6VXY6|uniprotkb:A2A303|uniprotkb:Q5TAM6 psi-mi:a0a0s2z547_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short) psi-mi:sgt1_human(display_long)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409587|imex:IM-26436-162 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030425"(dendrite)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:2000297"(negative regulation of synapse maturation)|refseq:NP_079290.1|refseq:NP_776089.2|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type) reactome:R-HSA-9660826|ensembl:ENSG00000165416(gene)|ensembl:ENST00000343788(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043947"(obsolete positive regulation by host of symbiont catalytic activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044563|mint:Q9Y2Z0|rcsb pdb:1RL1|reactome:R-HSA-844456|refseq:NP_001124384.1|refseq:NP_006695.1|refseq:NP_001307760.1|dip:DIP-53799N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gsaAAzUJZmyP+lbXd1xlMyk00lI9606 rogid:LZLjC25rgN9UOlExVzIfrWj8taE9606 rigid:9iQR1sKv7lXHMiJR2w/r6Ucsj2k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A0S2Z547 uniprotkb:P35241 intact:EBI-25409574 intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7 psi-mi:a0a0s2z547_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short) psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409587|imex:IM-26436-162 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030425"(dendrite)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:2000297"(negative regulation of synapse maturation)|refseq:NP_079290.1|refseq:NP_776089.2|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type) ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gsaAAzUJZmyP+lbXd1xlMyk00lI9606 rogid:75lzbINdL0deHtiWY7IwioSh5749606 rigid:9iQR1sKv7lXHMiJR2w/r6Ucsj2k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A0S2Z547 uniprotkb:P06454 intact:EBI-25409574 intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547 psi-mi:a0a0s2z547_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short) psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409587|imex:IM-26436-162 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030425"(dendrite)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:2000297"(negative regulation of synapse maturation)|refseq:NP_079290.1|refseq:NP_776089.2|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gsaAAzUJZmyP+lbXd1xlMyk00lI9606 rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606 rigid:9iQR1sKv7lXHMiJR2w/r6Ucsj2k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A0S2Z547 uniprotkb:Q96QC0 intact:EBI-25409574 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:a0a0s2z547_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409587|imex:IM-26436-162 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030425"(dendrite)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:2000297"(negative regulation of synapse maturation)|refseq:NP_079290.1|refseq:NP_776089.2|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type) refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gsaAAzUJZmyP+lbXd1xlMyk00lI9606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:9iQR1sKv7lXHMiJR2w/r6Ucsj2k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A0S2Z547 uniprotkb:P26038 intact:EBI-25409574 intact:EBI-528768|ensembl:ENSP00000353408 psi-mi:a0a0s2z547_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short) psi-mi:moes_human(display_long)|uniprotkb:Membrane-organizing extension spike protein(gene name synonym)|uniprotkb:MSN(gene name)|psi-mi:MSN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409587|imex:IM-26436-162 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030425"(dendrite)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:2000297"(negative regulation of synapse maturation)|refseq:NP_079290.1|refseq:NP_776089.2|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_002435.1|ensembl:ENSG00000147065(gene)|ensembl:ENST00000360270(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001931"(uropod)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005925"(focal adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0042098"(T cell proliferation)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070489"(T cell aggregation)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009986"(cell surface)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0072678"(T cell migration)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000401"(regulation of lymphocyte migration)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P26038|rcsb pdb:1E5W|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016323"(basolateral plasma membrane)|rcsb pdb:1EF1|rcsb pdb:1SGH|rcsb pdb:6TXQ|go:"GO:0016324"(apical plasma membrane)|rcsb pdb:6TXS|reactome:R-HSA-437239|reactome:R-HSA-8950505|reactome:R-HSA-9662360|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-9662361|go:"GO:0019901"(protein kinase binding)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0031143"(pseudopodium)|go:"GO:0031528"(microvillus membrane)|dip:DIP-33841N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gsaAAzUJZmyP+lbXd1xlMyk00lI9606 rogid:XYzuC8VtaVyNYyZ2G5wVbxyPPww9606 rigid:9iQR1sKv7lXHMiJR2w/r6Ucsj2k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A0S2Z547 uniprotkb:Q9Y3D9 intact:EBI-25409574 intact:EBI-1054270|uniprotkb:Q96Q24|uniprotkb:Q9BWH8|uniprotkb:Q9P053|uniprotkb:B2R6V3|ensembl:ENSP00000320184 psi-mi:a0a0s2z547_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short) psi-mi:rt23_human(display_long)|uniprotkb:MRPS23(gene name)|psi-mi:MRPS23(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS23(gene name synonym)|uniprotkb:CGI-138(orf name)|uniprotkb:HSPC329(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409587|imex:IM-26436-162 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030425"(dendrite)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:2000297"(negative regulation of synapse maturation)|refseq:NP_079290.1|refseq:NP_776089.2|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_057154.2|ensembl:ENSG00000181610(gene)|ensembl:ENST00000313608(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0031965"(nuclear membrane)|interpro:IPR019520|interpro:IPR023611|mint:Q9Y3D9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gsaAAzUJZmyP+lbXd1xlMyk00lI9606 rogid:6Iyu6KkT1Y0+n0LKWy5Gf0DkhHw9606 rigid:9iQR1sKv7lXHMiJR2w/r6Ucsj2k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A0S2Z547 uniprotkb:P15311 intact:EBI-25409574 intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042 psi-mi:a0a0s2z547_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short) psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409587|imex:IM-26436-162 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030425"(dendrite)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:2000297"(negative regulation of synapse maturation)|refseq:NP_079290.1|refseq:NP_776089.2|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type) ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gsaAAzUJZmyP+lbXd1xlMyk00lI9606 rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606 rigid:9iQR1sKv7lXHMiJR2w/r6Ucsj2k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A0S2Z547 uniprotkb:O43852 intact:EBI-25409574 intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364 psi-mi:a0a0s2z547_human(display_long)|uniprotkb:ARHGEF15(gene name)|psi-mi:ARHGEF15(display_short) psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409587|imex:IM-26436-162 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030425"(dendrite)|go:"GO:0061299"(retina vasculature morphogenesis in camera-type eye)|go:"GO:2000297"(negative regulation of synapse maturation)|refseq:NP_079290.1|refseq:NP_776089.2|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type) refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gsaAAzUJZmyP+lbXd1xlMyk00lI9606 rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606 rigid:9iQR1sKv7lXHMiJR2w/r6Ucsj2k false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:Q70IA6 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-2558739|uniprotkb:Q96M67|uniprotkb:B4DKP3 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:mob2_human(display_long)|uniprotkb:MOB2(gene name)|psi-mi:MOB2(display_short)|uniprotkb:HCCA2(gene name synonym)|uniprotkb:Mob2 homolog(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_001165694.1|refseq:NP_443731.2|interpro:IPR005301(Mob1/phocein)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR036703|mint:Q70IA6 - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:bPhfXMdT6x7s05Ufn4VZrMRgcL89606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:P15374 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-954554|uniprotkb:Q5TBK8|uniprotkb:Q6IBE9|ensembl:ENSP00000366819|uniprotkb:B2R970 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:uchl3_human(display_long)|uniprotkb:Ubiquitin thioesterase L3(gene name synonym)|uniprotkb:UCHL3(gene name)|psi-mi:UCHL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_001257881.1|refseq:NP_005993.1|ensembl:ENSG00000118939(gene)|ensembl:ENST00000377595(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043687"(post-translational protein modification)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|rcsb pdb:1UCH|rcsb pdb:1XD3|rcsb pdb:6ISU|rcsb pdb:6QML|reactome:R-HSA-5689603|reactome:R-HSA-8866652|reactome:R-HSA-8951664|dip:DIP-29135N - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:cPnctBpxrgvBKBSaQmhCsyd2nRM9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:Q07889 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-297487|intact:EBI-28968641|uniprotkb:A8K2G3|ensembl:ENSP00000384675|uniprotkb:B4DXG2 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:sos1_human(display_long)|uniprotkb:SOS1(gene name)|psi-mi:SOS1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_005624.2|ensembl:ENSP00000384675|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8983432|reactome:R-HSA-9013149|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9664565|reactome:R-HSA-9665348|ensembl:ENSG00000115904(gene)|ensembl:ENST00000402219(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001942"(hair follicle development)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007296"(vitellogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0060021"(roof of mouth development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:1904693"(midbrain morphogenesis)|go:"GO:2000973"(regulation of pro-B cell differentiation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|go:"GO:0005737"(cytoplasm)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR007125(Histone core)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR035899|interpro:IPR036964|mint:Q07889|rcsb pdb:1AWE|rcsb pdb:1BKD|rcsb pdb:1DBH|rcsb pdb:1NVU|rcsb pdb:1NVV|rcsb pdb:1NVW|rcsb pdb:1NVX|rcsb pdb:1Q9C|rcsb pdb:1XD2|rcsb pdb:1XD4|rcsb pdb:1XDV|rcsb pdb:2II0|rcsb pdb:3KSY|rcsb pdb:4NYI|rcsb pdb:4NYJ|rcsb pdb:4NYM|rcsb pdb:4URU|rcsb pdb:4URV|rcsb pdb:4URW|rcsb pdb:4URX|rcsb pdb:4URY|rcsb pdb:4URZ|rcsb pdb:4US0|rcsb pdb:4US1|rcsb pdb:4US2|rcsb pdb:5OVD|rcsb pdb:5OVE|rcsb pdb:5OVF|rcsb pdb:5OVG|rcsb pdb:5OVH|rcsb pdb:5OVI|rcsb pdb:5WFO|rcsb pdb:5WFP|rcsb pdb:5WFQ|rcsb pdb:5WFR|rcsb pdb:6BVI|rcsb pdb:6BVJ|rcsb pdb:6BVK|rcsb pdb:6BVL|rcsb pdb:6BVM|rcsb pdb:6CUO|rcsb pdb:6CUP|rcsb pdb:6CUR|rcsb pdb:6D55|rcsb pdb:6D56|rcsb pdb:6D59|rcsb pdb:6D5E|rcsb pdb:6D5G|rcsb pdb:6D5H|rcsb pdb:6D5J|rcsb pdb:6D5L|rcsb pdb:6D5M|rcsb pdb:6D5V|rcsb pdb:6D5W|rcsb pdb:6EPL|rcsb pdb:6EPM|rcsb pdb:6EPN|rcsb pdb:6EPO|rcsb pdb:6EPP|rcsb pdb:6F08|rcsb pdb:6SCM|rcsb pdb:6SFR|rcsb pdb:6V94|rcsb pdb:6V9F|rcsb pdb:6V9J|rcsb pdb:6V9L|rcsb pdb:6V9M|rcsb pdb:6V9N|rcsb pdb:6V9O|rcsb pdb:6Y44|rcsb pdb:7AVI|rcsb pdb:7AVL|rcsb pdb:7AVS|rcsb pdb:7AVT|rcsb pdb:7AVU|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|rcsb pdb:7AVV|rcsb pdb:7KFZ|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180336|reactome:R-HSA-186763|reactome:R-HSA-193648|reactome:R-HSA-1963640|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-416482|reactome:R-HSA-428540|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5655253|dip:DIP-31802N - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:SPXIrLMDF+XVcqKxBFgWsRGCFw89606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:P62308 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-624585|uniprotkb:Q15357|uniprotkb:Q6IB86|ensembl:ENSP00000272348|intact:EBI-1056206|uniprotkb:D6W5G6 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:ruxg_human(display_long)|uniprotkb:SNRPG(gene name)|psi-mi:SNRPG(display_short)|uniprotkb:PBSCG(gene name synonym)|uniprotkb:Sm protein G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 go:"GO:0097526"(spliceosomal tri-snRNP complex)|ensembl:ENSG00000143977(gene)|ensembl:ENST00000272348(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043186"(P granule)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034098|interpro:IPR044641|mint:P62308|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|refseq:NP_003087.1|dip:DIP-34627N - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:bwbnMaq7QstuUpgUyJtFqzF5J/I9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:Q6UWP8 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-11024569|uniprotkb:E9PBV3|uniprotkb:A8K5J0|ensembl:ENSP00000430242 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:sbsn_human(display_long)|uniprotkb:SBSN(gene name)|psi-mi:SBSN(display_short)|uniprotkb:UNQ698/PRO1343(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_001159506.1|refseq:NP_001159507.1|refseq:NP_940940.1|ensembl:ENSG00000189001(gene)|ensembl:ENST00000452271(transcript)|go:"GO:0070062"(extracellular exosome) - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:odagYPEdS9Vav1RDWyUv1l+lQA49606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:Q8TCU6 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-1046542|uniprotkb:E1P5X9|uniprotkb:Q5JS95|uniprotkb:Q5JS96|uniprotkb:Q69YL2|uniprotkb:Q7Z2L9|uniprotkb:Q9BQH0|uniprotkb:Q9BX55|uniprotkb:Q9H4Q6|uniprotkb:Q9P2D2|uniprotkb:Q9UGQ4|ensembl:ENSP00000361009 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:prex1_human(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_065871.2|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|rcsb pdb:3QIK|rcsb pdb:4YON|rcsb pdb:5D27|rcsb pdb:5D3V|rcsb pdb:5D3W|rcsb pdb:5D3X|rcsb pdb:5D3Y|rcsb pdb:5FI0|rcsb pdb:5FI1|rcsb pdb:6PCV|rcsb pdb:6VSK|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|ensembl:ENSG00000124126(gene)|ensembl:ENST00000371941(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042119"(neutrophil activation)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|dip:DIP-46975N - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:O75381 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-594898|uniprotkb:Q8WX51|uniprotkb:B2R7N1|uniprotkb:B3KML6|uniprotkb:B7Z1N2|intact:EBI-28983483|ensembl:ENSP00000349016 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:pex14_human(display_long)|uniprotkb:Peroxisomal membrane anchor protein PEX14(gene name synonym)|uniprotkb:PTS1 receptor-docking protein(gene name synonym)|uniprotkb:PEX14(gene name)|psi-mi:PEX14(display_short)|uniprotkb:Peroxin-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_004556.1|refseq:XP_011539882.1|ensembl:ENSP00000349016|ensembl:ENSG00000142655(gene)|ensembl:ENST00000356607(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036250"(peroxisome transport along microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044721"(protein import into peroxisome matrix, substrate release)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|mint:O75381|rcsb pdb:2W84|rcsb pdb:2W85|rcsb pdb:4BXU|reactome:R-HSA-8866654|reactome:R-HSA-9033241|reactome:R-HSA-9603798 - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:9RXZ+bR4fRStCHsMQihNHBhqmCo9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:O75340 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:P61457 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-740475|ensembl:ENSP00000299299|uniprotkb:P70519|uniprotkb:P80095|uniprotkb:Q9D930 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:phs_human(display_long)|uniprotkb:4-alpha-hydroxy-tetrahydropterin dehydratase(gene name synonym)|uniprotkb:Phenylalanine hydroxylase-stimulating protein(gene name synonym)|uniprotkb:Pterin carbinolamine dehydratase(gene name synonym)|uniprotkb:Dimerization cofactor of hepatocyte nuclear factor 1-alpha(gene name synonym)|uniprotkb:PCBD1(gene name)|psi-mi:PCBD1(display_short)|uniprotkb:DCOH(gene name synonym)|uniprotkb:PCBD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_000272.1|ensembl:ENSG00000166228(gene)|ensembl:ENST00000299299(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004505"(phenylalanine 4-monooxygenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006558"(L-phenylalanine metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0008124"(4-alpha-hydroxytetrahydrobiopterin dehydratase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001533(Transcriptional coactivator/pterin dehydratase)|interpro:IPR036428|mint:P61457|reactome:R-HSA-8964208|refseq:NP_001276726.1 - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:WsAu8slwInyWOA2p/z+JqTvyKP49606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:O43790 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-9996498|uniprotkb:P78387|ensembl:ENSP00000293525|ensembl:ENSP00000444533 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:krt86_human(display_long)|uniprotkb:KRT86(gene name)|psi-mi:KRT86(display_short)|uniprotkb:KRTHB6(gene name synonym)|uniprotkb:Hair keratin K2.11(gene name synonym)|uniprotkb:Keratin-86(gene name synonym)|uniprotkb:Type II hair keratin Hb6(gene name synonym)|uniprotkb:Type-II keratin Kb26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_001307127.1|refseq:XP_016874785.1|ensembl:ENSG00000170442(gene)|ensembl:ENST00000293525(transcript)|ensembl:ENST00000423955(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0045095"(keratin filament)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:gFNKiRED0NGx9wDcJXMAdfkaMhs9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:Q7Z353 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-1052734|uniprotkb:Q5JZB4|uniprotkb:Q96NK7|uniprotkb:A8K1Y5|uniprotkb:B7ZL18|ensembl:ENSP00000297977|ensembl:ENSP00000362272 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:hdx_human(display_long)|uniprotkb:HDX(gene name)|psi-mi:HDX(display_short)|uniprotkb:CXorf43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_001170949.1|refseq:NP_001170950.1|refseq:NP_653258.2|refseq:XP_011529165.1|refseq:XP_011529166.1|refseq:XP_006724682.1|ensembl:ENSG00000165259(gene)|ensembl:ENST00000297977(transcript)|ensembl:ENST00000373177(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|rcsb pdb:2DA4|refseq:XP_016884763.1 - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:nhMJWu8xnF2FDhtzcHcpjLftNjE9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:Q13642 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K0Q5 uniprotkb:Q02413 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409623|imex:IM-26436-310 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606 rigid:XK3qo8AIMSGStZaWowz5xZixBsI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BZ29 uniprotkb:Q5JSL3 intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761 intact:EBI-2796556|uniprotkb:Q6ZUJ5|uniprotkb:Q86VU8|uniprotkb:A6NMF0|uniprotkb:Q66M66|uniprotkb:Q96MN3|ensembl:ENSP00000276202 psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym) psi-mi:doc11_human(display_long)|uniprotkb:ZIZ2(gene name synonym)|uniprotkb:Activated Cdc42-associated guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Zizimin-2(gene name synonym)|uniprotkb:DOCK11(gene name)|psi-mi:DOCK11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409655|imex:IM-26436-204 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_653259.3|ensembl:ENSG00000147251(gene)|ensembl:ENST00000276202(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051491"(positive regulation of filopodium assembly)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606 rogid:7m+XrwK8pcFj5RtMPxrTNgJs0qc9606 rigid:BbbjFOjGfL0OYC/Mczp/nG53jkk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BZ29 uniprotkb:Q14185 intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761 intact:EBI-446740|uniprotkb:A9Z1Z5|ensembl:ENSP00000280333 psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym) psi-mi:dock1_human(display_long)|uniprotkb:180 kDa protein downstream of CRK(gene name synonym)|uniprotkb:DOCK1(gene name)|psi-mi:DOCK1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409655|imex:IM-26436-204 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 ensembl:ENSP00000280333|dip:DIP-29391N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000150760(gene)|ensembl:ENST00000280333(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|mint:Q14185|rcsb pdb:3L4C|reactome:R-HSA-2029482|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9664422|reactome:R-HSA-983231|interpro:IPR043162|refseq:NP_001371.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606 rogid:SsN4jN+OIbDOnPEthCF7ZdEJrdc9606 rigid:BbbjFOjGfL0OYC/Mczp/nG53jkk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BZ29 uniprotkb:P62633 intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761 intact:EBI-1047529|uniprotkb:D3DNB9|uniprotkb:D3DNC0|uniprotkb:D3DNC1|uniprotkb:P20694|uniprotkb:Q5QJR0|uniprotkb:Q6PJI7|uniprotkb:Q96NV3|uniprotkb:B4DP17|uniprotkb:Q4JGY1|uniprotkb:B2RAV9|uniprotkb:Q4JGY0|uniprotkb:Q5U0E9|ensembl:ENSP00000410619|uniprotkb:A8K7V4|uniprotkb:E9PDR7 psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym) psi-mi:cnbp_human(display_long)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:CNBP(gene name)|psi-mi:CNBP(display_short)|uniprotkb:ZNF9(gene name synonym)|uniprotkb:RNF163(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409655|imex:IM-26436-204 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_001120664.1|refseq:NP_001120668.1|refseq:NP_003409.1|refseq:NP_001120665.1|refseq:NP_001120666.1|ensembl:ENSG00000169714(gene)|ensembl:ENST00000422453(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P62633|refseq:NP_001120667.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606 rogid:x5yqfxy/s3fE/6EmvjrEe7PmanQ9606 rigid:BbbjFOjGfL0OYC/Mczp/nG53jkk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BZ29 uniprotkb:O14646 intact:EBI-2695893|uniprotkb:Q5TAN8|uniprotkb:Q9BZ25|uniprotkb:Q9BZ26|uniprotkb:Q5T2Q1|uniprotkb:Q5JUD6|uniprotkb:Q5JUD4|uniprotkb:Q9BZ27|uniprotkb:Q9BZ28|uniprotkb:Q9UPU4|uniprotkb:B3KX25|uniprotkb:E9PFM9|ensembl:ENSP00000498761 intact:EBI-1560858|uniprotkb:Q17RZ3|ensembl:ENSP00000284049|ensembl:ENSP00000483667 psi-mi:dock9_human(display_long)|uniprotkb:Cdc42 guanine nucleotide exchange factor zizimin-1(gene name synonym)|uniprotkb:KIAA1058(gene name synonym)|uniprotkb:DOCK9(gene name)|psi-mi:DOCK9(display_short)|uniprotkb:ZIZ1(gene name synonym) psi-mi:chd1_human(display_long)|uniprotkb:ATP-dependent helicase CHD1(gene name synonym)|uniprotkb:CHD1(gene name)|psi-mi:CHD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409655|imex:IM-26436-204 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305778.1|refseq:NP_001123520.1|refseq:NP_001123521.1|refseq:NP_001123522.1|refseq:NP_056111.1|ensembl:ENSG00000088387(gene)|ensembl:ENST00000652315(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR026796|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037809|interpro:IPR043161|interpro:IPR043162|mint:Q9BZ29|rcsb pdb:1WG7|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_001261.2|refseq:XP_005271924.1|dip:DIP-38922N|ensembl:ENSG00000153922(gene)|ensembl:ENST00000284049(transcript)|ensembl:ENST00000614616(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|mint:O14646|rcsb pdb:2B2T|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2B2Y|rcsb pdb:2N39|rcsb pdb:4B4C|rcsb pdb:4NW2|rcsb pdb:4O42|rcsb pdb:5AFW|reactome:R-HSA-9018519 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0uqFLEeF0UV1x4KlrfoX0pEdj7g9606 rogid:KzH9c8MyoQh0Ph+KwSUktSa5qWM9606 rigid:BbbjFOjGfL0OYC/Mczp/nG53jkk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12774 uniprotkb:P09012 intact:EBI-602199|uniprotkb:A6NNJ2|uniprotkb:Q6ZML7|ensembl:ENSP00000056217 intact:EBI-607085|ensembl:ENSP00000243563 psi-mi:arhg5_human(display_long)|uniprotkb:Guanine nucleotide regulatory protein TIM(gene name synonym)|uniprotkb:Oncogene TIM(gene name synonym)|uniprotkb:p60 TIM(gene name synonym)|uniprotkb:Transforming immortalized mammary oncogene(gene name synonym)|uniprotkb:ARHGEF5(gene name)|psi-mi:ARHGEF5(display_short)|uniprotkb:TIM(gene name synonym)|uniprotkb:Ephexin-3(gene name synonym) psi-mi:snrpa_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409676|imex:IM-26436-166 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005426.2|ensembl:ENSP00000056217|ensembl:ENST00000471847|ensembl:ENSP00000418227|ensembl:ENSG00000050327(gene)|ensembl:ENST00000056217(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0030054"(cell junction)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904591"(positive regulation of protein import)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029212|interpro:IPR035899|interpro:IPR036028|mint:Q12774|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|ensembl:ENSG00000077312(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034407|interpro:IPR034409|interpro:IPR035979|mint:P09012|rcsb pdb:1AUD|ensembl:ENST00000243563(transcript)|rcsb pdb:1DRZ|rcsb pdb:1DZ5|rcsb pdb:1FHT|rcsb pdb:1M5K|rcsb pdb:1M5O|rcsb pdb:1M5P|rcsb pdb:1M5V|rcsb pdb:1NU4|rcsb pdb:1OIA|rcsb pdb:1SJ3|rcsb pdb:1SJ4|rcsb pdb:1SJF|rcsb pdb:1U6B|rcsb pdb:1URN|rcsb pdb:1VBX|rcsb pdb:1VBY|rcsb pdb:1VBZ|rcsb pdb:1VC0|rcsb pdb:1VC5|rcsb pdb:1VC6|rcsb pdb:1ZZN|rcsb pdb:2A3J|rcsb pdb:2NZ4|rcsb pdb:2OIH|rcsb pdb:2OJ3|rcsb pdb:2U1A|rcsb pdb:3BO2|rcsb pdb:3BO3|rcsb pdb:3BO4|rcsb pdb:3CUL|rcsb pdb:3CUN|rcsb pdb:3EGZ|rcsb pdb:3G8S|rcsb pdb:3G8T|rcsb pdb:3G96|rcsb pdb:3G9C|rcsb pdb:3HHN|rcsb pdb:3IIN|rcsb pdb:3IRW|rcsb pdb:3IWN|rcsb pdb:3K0J|rcsb pdb:3L3C|rcsb pdb:3MUM|rcsb pdb:3MUR|rcsb pdb:3MUT|rcsb pdb:3R1H|rcsb pdb:3R1L|rcsb pdb:3UCU|rcsb pdb:3UCZ|rcsb pdb:3UD3|rcsb pdb:3UD4|rcsb pdb:3MUV|rcsb pdb:3UTR|rcsb pdb:4C4W|rcsb pdb:4PR6|rcsb pdb:4PRF|rcsb pdb:4W90|rcsb pdb:4W92|rcsb pdb:3MXH|rcsb pdb:3P49|rcsb pdb:3PGW|rcsb pdb:4YB1|rcsb pdb:5DDO|rcsb pdb:5DDP|rcsb pdb:5DDQ|rcsb pdb:5DDR|rcsb pdb:5FJ4|rcsb pdb:6LAS|rcsb pdb:6LAU|rcsb pdb:6LAX|rcsb pdb:6LAZ|rcsb pdb:6QX9|rcsb pdb:6SQN|rcsb pdb:6SQQ|rcsb pdb:6SQT|rcsb pdb:6SQV|rcsb pdb:6SR7|rcsb pdb:6XH0|rcsb pdb:6XH1|rcsb pdb:6XH2|rcsb pdb:6XH3|rcsb pdb:7AEP|rcsb pdb:7B0Y|rcsb pdb:7D7V|rcsb pdb:7LHX|reactome:R-HSA-72163|refseq:NP_004587.1|dip:DIP-29407N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:vSJp2o8EnxIPS2WJ6M+5mRLZyEw9606 rogid:BJ9zdDzOPs9JYgU8lErj/maq0AY9606 rigid:+ASpnEguHw4NphfIIs8GCOD0hew false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12774 uniprotkb:O95292 intact:EBI-602199|uniprotkb:A6NNJ2|uniprotkb:Q6ZML7|ensembl:ENSP00000056217 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:arhg5_human(display_long)|uniprotkb:Guanine nucleotide regulatory protein TIM(gene name synonym)|uniprotkb:Oncogene TIM(gene name synonym)|uniprotkb:p60 TIM(gene name synonym)|uniprotkb:Transforming immortalized mammary oncogene(gene name synonym)|uniprotkb:ARHGEF5(gene name)|psi-mi:ARHGEF5(display_short)|uniprotkb:TIM(gene name synonym)|uniprotkb:Ephexin-3(gene name synonym) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409676|imex:IM-26436-166 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005426.2|ensembl:ENSP00000056217|ensembl:ENST00000471847|ensembl:ENSP00000418227|ensembl:ENSG00000050327(gene)|ensembl:ENST00000056217(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0030054"(cell junction)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904591"(positive regulation of protein import)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029212|interpro:IPR035899|interpro:IPR036028|mint:Q12774|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408 refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:vSJp2o8EnxIPS2WJ6M+5mRLZyEw9606 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rigid:+ASpnEguHw4NphfIIs8GCOD0hew false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12774 uniprotkb:P62993 intact:EBI-602199|uniprotkb:A6NNJ2|uniprotkb:Q6ZML7|ensembl:ENSP00000056217 intact:EBI-401755|ensembl:ENSP00000339007|uniprotkb:P29354|uniprotkb:Q14450|uniprotkb:Q63057|uniprotkb:Q63059|ensembl:ENSP00000376345|ensembl:ENSP00000376347|ensembl:ENSP00000496913 psi-mi:arhg5_human(display_long)|uniprotkb:Guanine nucleotide regulatory protein TIM(gene name synonym)|uniprotkb:Oncogene TIM(gene name synonym)|uniprotkb:p60 TIM(gene name synonym)|uniprotkb:Transforming immortalized mammary oncogene(gene name synonym)|uniprotkb:ARHGEF5(gene name)|psi-mi:ARHGEF5(display_short)|uniprotkb:TIM(gene name synonym)|uniprotkb:Ephexin-3(gene name synonym) psi-mi:grb2_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409676|imex:IM-26436-166 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005426.2|ensembl:ENSP00000056217|ensembl:ENST00000471847|ensembl:ENSP00000418227|ensembl:ENSG00000050327(gene)|ensembl:ENST00000056217(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0030054"(cell junction)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904591"(positive regulation of protein import)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029212|interpro:IPR035899|interpro:IPR036028|mint:Q12774|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408 ensembl:ENSG00000177885(gene)|refseq:NP_002077.1|refseq:NP_987102.1|ensembl:ENST00000316804(transcript)|ensembl:ENST00000392562(transcript)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|ensembl:ENST00000392564(transcript)|ensembl:ENST00000648046(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0012506"(vesicle membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|mint:P62993|rcsb pdb:1AZE|rcsb pdb:1BM2|rcsb pdb:1BMB|rcsb pdb:1CJ1|rcsb pdb:1FHS|rcsb pdb:1FYR|rcsb pdb:1GCQ|rcsb pdb:1GFC|rcsb pdb:1GFD|rcsb pdb:1GHU|rcsb pdb:1GRI|rcsb pdb:1IO6|rcsb pdb:1JYQ|rcsb pdb:1JYR|rcsb pdb:1JYU|rcsb pdb:1QG1|rcsb pdb:1TZE|rcsb pdb:1X0N|rcsb pdb:1ZFP|rcsb pdb:2AOA|rcsb pdb:2AOB|rcsb pdb:2H46|rcsb pdb:2H5K|rcsb pdb:2HUW|rcsb pdb:2VVK|rcsb pdb:2VWF|rcsb pdb:2W0Z|rcsb pdb:3C7I|rcsb pdb:3IMD|rcsb pdb:3IMJ|rcsb pdb:3IN7|rcsb pdb:3IN8|rcsb pdb:3KFJ|rcsb pdb:3MXC|rcsb pdb:3N7Y|rcsb pdb:3N84|rcsb pdb:3N8M|rcsb pdb:3OV1|rcsb pdb:3OVE|rcsb pdb:3MXY|rcsb pdb:3S8L|rcsb pdb:3S8N|rcsb pdb:3S8O|rcsb pdb:3WA4|rcsb pdb:4P9V|rcsb pdb:4P9Z|rcsb pdb:5CDW|rcsb pdb:6ICG|rcsb pdb:6ICH|rcsb pdb:6SDF|rcsb pdb:6VK2|rcsb pdb:6WM1|rcsb pdb:6WO2|reactome:R-HSA-109704|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2029482|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-388841|reactome:R-HSA-389359|reactome:R-HSA-391160|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8865999|reactome:R-HSA-8875360|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8983432|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028335|reactome:R-HSA-5654689|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9645135|reactome:R-HSA-9664422|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|dip:DIP-29229N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:vSJp2o8EnxIPS2WJ6M+5mRLZyEw9606 rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606 rigid:+ASpnEguHw4NphfIIs8GCOD0hew false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12774 uniprotkb:P46109 intact:EBI-602199|uniprotkb:A6NNJ2|uniprotkb:Q6ZML7|ensembl:ENSP00000056217 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:arhg5_human(display_long)|uniprotkb:Guanine nucleotide regulatory protein TIM(gene name synonym)|uniprotkb:Oncogene TIM(gene name synonym)|uniprotkb:p60 TIM(gene name synonym)|uniprotkb:Transforming immortalized mammary oncogene(gene name synonym)|uniprotkb:ARHGEF5(gene name)|psi-mi:ARHGEF5(display_short)|uniprotkb:TIM(gene name synonym)|uniprotkb:Ephexin-3(gene name synonym) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409676|imex:IM-26436-166 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005426.2|ensembl:ENSP00000056217|ensembl:ENST00000471847|ensembl:ENSP00000418227|ensembl:ENSG00000050327(gene)|ensembl:ENST00000056217(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0030054"(cell junction)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904591"(positive regulation of protein import)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029212|interpro:IPR035899|interpro:IPR036028|mint:Q12774|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408 refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:vSJp2o8EnxIPS2WJ6M+5mRLZyEw9606 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 rigid:+ASpnEguHw4NphfIIs8GCOD0hew false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:Q92922 intact:EBI-25409690 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:Q8WUF5 intact:EBI-25409690 intact:EBI-5550163|uniprotkb:Q2PNZ9|uniprotkb:Q5DU71|uniprotkb:Q5I1X4|uniprotkb:Q6P1R7|uniprotkb:Q6PKF8|uniprotkb:Q9Y290|ensembl:ENSP00000354218|ensembl:ENSP00000403902 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:iaspp_human(display_long)|uniprotkb:PPP1R13L(gene name)|psi-mi:PPP1R13L(display_short)|uniprotkb:IASPP(gene name synonym)|uniprotkb:NKIP1(gene name synonym)|uniprotkb:PPP1R13BL(gene name synonym)|uniprotkb:RAI(gene name synonym)|uniprotkb:Inhibitor of ASPP protein(gene name synonym)|uniprotkb:NFkB-interacting protein 1(gene name synonym)|uniprotkb:PPP1R13B-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) refseq:NP_001135974.1|refseq:NP_006654.2|refseq:XP_016881666.1|refseq:XP_016881667.1|dip:DIP-29586N|ensembl:ENSG00000104881(gene)|ensembl:ENST00000360957(transcript)|ensembl:ENST00000418234(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0030054"(cell junction)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042633"(hair cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028320|interpro:IPR036028|interpro:IPR036770|interpro:IPR042722|mint:Q8WUF5|rcsb pdb:2VGE|rcsb pdb:6DCX|rcsb pdb:6HL6|rcsb pdb:6RZ3|reactome:R-HSA-6804759 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:0MfBf9sG2+pc4Isd+GDCBm6b9Eo9606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:P25205 intact:EBI-25409690 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:Q96CX2 intact:EBI-25409690 intact:EBI-358358|ensembl:ENSP00000366694 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:P12268 intact:EBI-25409690 intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:Q8N1I0 intact:EBI-25409690 intact:EBI-1059186|uniprotkb:O14584|uniprotkb:O94824|uniprotkb:Q8NB45|ensembl:ENSP00000404179 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:dock4_human(display_long)|uniprotkb:DOCK4(gene name)|psi-mi:DOCK4(display_short)|uniprotkb:KIAA0716(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) ensembl:ENST00000428084|ensembl:ENSP00000410746|ensembl:ENSP00000404179|refseq:NP_055520.3|refseq:XP_006716251.1|refseq:XP_006716252.1|ensembl:ENSG00000128512(gene)|ensembl:ENST00000437633(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|interpro:IPR032376|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|interpro:IPR035769|interpro:IPR035892|interpro:IPR036028|interpro:IPR037014|interpro:IPR037811 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:gfkRZEKBQCgsZ/zjJ8NWqL3uJZk9606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:Q9NX63 intact:EBI-25409690 intact:EBI-743375|ensembl:ENSP00000262570 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) go:"GO:0008053"(mitochondrial fusion)|refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554(gene)|ensembl:ENST00000262570(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0019902"(phosphatase binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:Q9Y6H1 intact:EBI-25409690 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5SSL4-2 uniprotkb:Q8IX12 intact:EBI-25409690 intact:EBI-356265|ensembl:ENSP00000265872|uniprotkb:A0JLT7|uniprotkb:A1L4P7|uniprotkb:A8K9D4|uniprotkb:B4DNP8|uniprotkb:B4DRK8|uniprotkb:Q5EBM3|uniprotkb:Q32NE3|uniprotkb:Q5VUP6|uniprotkb:Q6PIZ0|uniprotkb:Q6X935|uniprotkb:Q9H8N4|uniprotkb:Q9NVA7|uniprotkb:Q9NVQ0|uniprotkb:Q9NWM6 psi-mi:q5ssl42(display_long)|uniprotkb:Abr(gene name)|psi-mi:Abr(display_short) psi-mi:ccar1_human(display_long)|uniprotkb:CCAR1(gene name)|psi-mi:CCAR1(display_short)|uniprotkb:CARP1(gene name synonym)|uniprotkb:DIS(gene name synonym)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Death inducer with SAP domain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409695|imex:IM-26436-168 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5SSL4-2(isoform-parent) ensembl:ENSG00000060339(gene)|ensembl:ENST00000265872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8IX12|reactome:R-HSA-72163|refseq:NP_060707.2|refseq:NP_001269888.1|refseq:NP_001269889.1|dip:DIP-27607N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XA1XahjoVzwqErCw/G68hQvSK+810090 rogid:YnZve7StC4kAO8raUbp8T02jpe09606 rigid:CnLGtWtNbfLBRBwW057JKVC81cg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12802-1 uniprotkb:P17612 intact:EBI-25409719|ensembl:ENSP00000378026 intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940 psi-mi:q12802-1(display_long)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym) psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409729|imex:IM-26436-94 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1373806(isoform-parent)|ensembl:ENSG00000170776(gene)|ensembl:ENST00000394518(transcript) refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606 rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606 rigid:QU6fMKVhfxzLTZdfs1RR1CiJU6c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12802-1 uniprotkb:P13861 intact:EBI-25409719|ensembl:ENSP00000378026 intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724 psi-mi:q12802-1(display_long)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym) psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409729|imex:IM-26436-94 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1373806(isoform-parent)|ensembl:ENSG00000170776(gene)|ensembl:ENST00000394518(transcript) dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606 rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606 rigid:QU6fMKVhfxzLTZdfs1RR1CiJU6c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12802-1 uniprotkb:O60583 intact:EBI-25409719|ensembl:ENSP00000378026 intact:EBI-2836757|uniprotkb:Q5I1Y0|uniprotkb:A8KA48|uniprotkb:Q29R66|uniprotkb:Q53SR4|uniprotkb:O60582|uniprotkb:D3DP73|uniprotkb:D3DP74|ensembl:ENSP00000264157 psi-mi:q12802-1(display_long)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym) psi-mi:ccnt2_human(display_long)|uniprotkb:CCNT2(gene name)|psi-mi:CCNT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409729|imex:IM-26436-94 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1373806(isoform-parent)|ensembl:ENSG00000170776(gene)|ensembl:ENST00000394518(transcript) refseq:NP_001232.1|refseq:NP_490595.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019085"(early viral transcription)|go:"GO:0019086"(late viral transcription)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0097322"(7SK snRNA binding)|ensembl:ENSG00000082258(gene)|ensembl:ENST00000264157(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR028862|interpro:IPR036915|interpro:IPR043198|mint:O60583|rcsb pdb:2IVX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|interpro:IPR013763(Cyclin-related) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606 rogid:v1mUPCNA+Plg8UioUhIj1LL52fI9606 rigid:QU6fMKVhfxzLTZdfs1RR1CiJU6c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12802-1 uniprotkb:P07355 intact:EBI-25409719|ensembl:ENSP00000378026 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:q12802-1(display_long)|uniprotkb:AKAP-Lbc(gene name synonym)|uniprotkb:Breast cancer nuclear receptor-binding auxiliary protein(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor Lbc(gene name synonym)|uniprotkb:Human thyroid-anchoring protein 31(gene name synonym)|uniprotkb:Lymphoid blast crisis oncogene(gene name synonym)|uniprotkb:Non-oncogenic Rho GTPase-specific GTP exchange factor(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 13(gene name synonym)|uniprotkb:p47(gene name synonym)|uniprotkb:AKAP13(gene name)|psi-mi:AKAP13(display_short)|uniprotkb:BRX(gene name synonym)|uniprotkb:HT31(gene name synonym)|uniprotkb:LBC(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409729|imex:IM-26436-94 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1373806(isoform-parent)|ensembl:ENSG00000170776(gene)|ensembl:ENST00000394518(transcript) refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:pHHpKUh10J/O/fp06k4NaNhJF6U9606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:QU6fMKVhfxzLTZdfs1RR1CiJU6c false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:Q8N726 intact:EBI-25409743 intact:EBI-625922|uniprotkb:Q13195|uniprotkb:Q13399|uniprotkb:Q16360|uniprotkb:Q7KZR9|ensembl:ENSP00000432664|ensembl:ENSP00000462950|uniprotkb:D3DRK2 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:arf_human(display_long)|uniprotkb:p14ARF(gene name synonym)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:MLM(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) ensembl:ENSG00000147889(gene)|ensembl:ENST00000530628(transcript)|ensembl:ENST00000579755(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0050821"(protein stabilization)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090398"(cellular senescence)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|mint:Q8N726|reactome:R-HSA-111471|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-6804757|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9645722|reactome:R-HSA-9646303|reactome:R-HSA-9646304|refseq:NP_478102.2|dip:DIP-24171N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:zdbvJmkrI/zJFL+Enq5jTM1Csdw9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P22392 intact:EBI-25409743 intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:O75821 intact:EBI-25409743 intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P11441 intact:EBI-25409743 intact:EBI-356983|uniprotkb:Q5HY80|ensembl:ENSP00000358674 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:ubl4a_human(display_long)|uniprotkb:UBL4A(gene name)|psi-mi:UBL4A(display_short)|uniprotkb:GDX(gene name synonym)|uniprotkb:DXS254E(gene name synonym)|uniprotkb:UBL4(gene name synonym)|uniprotkb:Ubiquitin-like protein GDX(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_055050.1|ensembl:ENSG00000102178(gene)|ensembl:ENST00000369660(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016020"(membrane)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR041421|interpro:IPR044724|mint:P11441|rcsb pdb:2DZI|rcsb pdb:4WWR|rcsb pdb:4X86|reactome:R-HSA-9609523 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:euKOrDRC1mx0s2QVY95010PRaIg9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:Q9UI30 intact:EBI-25409743 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P43487 intact:EBI-25409743 intact:EBI-1032909|uniprotkb:Q53EY3|ensembl:ENSP00000327583 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:rang_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002873.1|ensembl:ENSG00000099901(gene)|ensembl:ENST00000331821(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1K5D|rcsb pdb:1K5G|reactome:R-HSA-165054|refseq:NP_001265568.1|refseq:NP_001265569.1|dip:DIP-35058N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:OWndphaUCDSO3+MGhJqcuQo2Lk09606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:Q92930 intact:EBI-25409743 intact:EBI-1760095|uniprotkb:Q9P293|uniprotkb:Q5JPC4|ensembl:ENSP00000312734 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:rab8b_human(display_long)|uniprotkb:RAB8B(gene name)|psi-mi:RAB8B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_057614.1|ensembl:ENSG00000166128(gene)|ensembl:ENST00000321437(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016604"(nuclear body)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051286"(cell tip)|go:"GO:0051461"(positive regulation of corticotropin secretion)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0150115"(cell-substrate junction organization)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q92930|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:1EzHoU6jEdli/t9gfwMBDjW3fNI9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P61006 intact:EBI-25409743 intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_005361.2|dip:DIP-43703N|ensembl:ENSG00000167461(gene)|ensembl:ENST00000300935(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P51148 intact:EBI-25409743 intact:EBI-1054923|intact:EBI-2798296|uniprotkb:Q9P0Y5|uniprotkb:Q6FH55|uniprotkb:F8W1H5|ensembl:ENSP00000345689|ensembl:ENSP00000377440 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:rab5c_human(display_long)|uniprotkb:RABL(gene name synonym)|uniprotkb:RAB5C(gene name)|psi-mi:RAB5C(display_short)|uniprotkb:RAB5L(gene name synonym)|uniprotkb:L1880(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_004574.2|refseq:NP_958842.1|refseq:XP_011523392.1|refseq:XP_011523393.1|refseq:NP_001238968.1|ensembl:ENSG00000108774(gene)|ensembl:ENST00000346213(transcript)|ensembl:ENST00000393860(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:4KYI|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:sz3lmmxPJk0/IzQ9dZF0PzfNhBY9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P20339 intact:EBI-25409743 intact:EBI-399437|uniprotkb:B4DJA5|intact:EBI-1048179|uniprotkb:Q6FI44|ensembl:ENSP00000273047 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:rab5a_human(display_long)|uniprotkb:RAB5A(gene name)|psi-mi:RAB5A(display_short)|uniprotkb:RAB5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_004153.2|refseq:NP_001278977.1|dip:DIP-380N|ensembl:ENSG00000144566(gene)|ensembl:ENST00000273047(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098559"(cytoplasmic side of early endosome membrane)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20339|rcsb pdb:1N6H|rcsb pdb:1N6I|rcsb pdb:1N6K|rcsb pdb:1N6L|rcsb pdb:1N6N|rcsb pdb:1N6O|rcsb pdb:1N6P|rcsb pdb:1N6R|rcsb pdb:1R2Q|rcsb pdb:1TU3|rcsb pdb:1TU4|rcsb pdb:3MJH|rcsb pdb:4Q9U|rcsb pdb:7BL1|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9636383|reactome:R-HSA-983231 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:SgowwV7QSVCvfsqSDE+6CHmPmKA9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:Q13636 intact:EBI-25409743 intact:EBI-725987|uniprotkb:Q15770|uniprotkb:Q9HC00|uniprotkb:B2RBT7|ensembl:ENSP00000461945 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:rab31_human(display_long)|uniprotkb:Ras-related protein Rab-22B(gene name synonym)|uniprotkb:RAB31(gene name)|psi-mi:RAB31(display_short)|uniprotkb:RAB22B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_006859.2|ensembl:ENSG00000168461(gene)|ensembl:ENST00000578921(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036186"(early phagosome membrane)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0090382"(phagosome maturation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2FG5|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:aM3EF6aRh9xb5TvDdURZacFdpSQ9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P51665 intact:EBI-25409743 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:O43242 intact:EBI-25409743 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:Q9UNM6 intact:EBI-25409743 intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:iOxE62MMeGx+aqsrir/LukJqeho9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:O00231 intact:EBI-25409743 intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:BgQKXK7gMMihacRCI+g/pBnRN309606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P28074 intact:EBI-25409743 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P28070 intact:EBI-25409743 intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P49721 intact:EBI-25409743 intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P20618 intact:EBI-25409743 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:O14818 intact:EBI-25409743 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P60900 intact:EBI-25409743 intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P25787 intact:EBI-25409743 intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P25786 intact:EBI-25409743 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:O15212 intact:EBI-25409743 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - crc64:8F138EAAE512A312 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:Q01968 intact:EBI-25409743 intact:EBI-6148898|uniprotkb:O60800|uniprotkb:Q15684|uniprotkb:A6NKI1|uniprotkb:Q9UMA5|uniprotkb:Q4VY09|uniprotkb:Q5JQF2|uniprotkb:A8KAP2|uniprotkb:Q15774|uniprotkb:Q5JQF1|uniprotkb:Q9UJG5|uniprotkb:Q4VY10|uniprotkb:B7ZLX2|ensembl:ENSP00000360154 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:ocrl_human(display_long)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym)|uniprotkb:OCRL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_000267.2|refseq:NP_001578.2|dip:DIP-45092N|ensembl:ENSG00000122126(gene)|ensembl:ENST00000371113(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|go:"GO:0052745"(inositol phosphate phosphatase activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061024"(membrane organization)|interpro:IPR000198(RhoGAP)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031995|interpro:IPR036691|interpro:IPR037787|interpro:IPR037793|mint:Q01968|rcsb pdb:2KIE|rcsb pdb:2QV2|rcsb pdb:3QBT|rcsb pdb:3QIS|rcsb pdb:4CMN|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1855183|reactome:R-HSA-1855204|reactome:R-HSA-432722|reactome:R-HSA-8856828|reactome:R-HSA-9013409|reactome:R-HSA-9013423 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:vbBQzhjgvm07+wOJkWgz+dyEBI49606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:P09429 intact:EBI-25409743 intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:Q04760 intact:EBI-25409743 intact:EBI-1055525|uniprotkb:P78375|uniprotkb:Q5TZW3|uniprotkb:Q96FC0|uniprotkb:Q96J41|uniprotkb:B4DDV0|uniprotkb:Q59EL0|uniprotkb:B2R6P7|ensembl:ENSP00000362463 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:lgul_human(display_long)|uniprotkb:Methylglyoxalase(gene name synonym)|uniprotkb:Aldoketomutase(gene name synonym)|uniprotkb:Glyoxalase I(gene name synonym)|uniprotkb:Ketone-aldehyde mutase(gene name synonym)|uniprotkb:S-D-lactoylglutathione methylglyoxal lyase(gene name synonym)|uniprotkb:GLO1(gene name)|psi-mi:GLO1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) refseq:NP_006699.2|ensembl:ENSG00000124767(gene)|ensembl:ENST00000373365(transcript)|go:"GO:0004462"(lactoylglutathione lyase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004360(Glyoxalase/bleomycin resistance protein/dioxygenase)|interpro:IPR004361(Glyoxalase I)|interpro:IPR018146|interpro:IPR029068|interpro:IPR037523|rcsb pdb:1BH5|rcsb pdb:1FRO|rcsb pdb:1QIN|rcsb pdb:1QIP|rcsb pdb:3VW9|rcsb pdb:3W0T|rcsb pdb:3W0U|reactome:R-HSA-70268 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:Oe1lCyzzD2y1WeArvZ74cYu9M1w9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8K337-1 uniprotkb:Q9UKG1 intact:EBI-25409743 intact:EBI-741243|intact:EBI-28979536|ensembl:ENSP00000288266|ensembl:ENSP00000498115|uniprotkb:Q9P2B9 psi-mi:q8k3371(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short) psi-mi:dp13a_human(display_long)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)|uniprotkb:APPL1(gene name)|psi-mi:APPL1(display_short)|uniprotkb:APPL(gene name synonym)|uniprotkb:DIP13A(gene name synonym)|uniprotkb:KIAA1428(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409748|imex:IM-26436-122 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8K337-1(isoform-parent) ensembl:ENSG00000157500(gene)|ensembl:ENST00000288266(transcript)|ensembl:ENST00000650354(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR027267|interpro:IPR037929|mint:Q9UKG1|rcsb pdb:2EJ8|rcsb pdb:2ELA|rcsb pdb:2ELB|rcsb pdb:2Q12|rcsb pdb:2Q13|rcsb pdb:2Z0N|rcsb pdb:2Z0O|rcsb pdb:5C5B|reactome:R-HSA-418889|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_036228.1|ensembl:ENSP00000288266|ensembl:ENSP00000498115|dip:DIP-29322N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/QpQ4L4lt4lovKO/aom2HO4PdNY10090 rogid:v94zzPKDww+kZxRttd3FHIXIx/w9606 rigid:ZclzYdMzqdoBnoz3OXCBSwtaNJI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:Q8IYB3 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-1055880|uniprotkb:O60585|uniprotkb:Q5VVN4|ensembl:ENSP00000326261 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:srrm1_human(display_long)|uniprotkb:SRRM1(gene name)|psi-mi:SRRM1(display_short)|uniprotkb:SRM160(gene name synonym)|uniprotkb:Ser/Arg-related nuclear matrix protein(gene name synonym)|uniprotkb:SR-related nuclear matrix protein of 160 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 refseq:NP_001290377.1|refseq:NP_001290378.1|refseq:NP_005830.2|ensembl:ENSG00000133226(gene)|ensembl:ENST00000323848(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR036483|mint:Q8IYB3|rcsb pdb:1MP1|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013422|reactome:R-HSA-9013418 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:x9vhX2HWCy5mm29U2xVXxj1GJw09606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:O43318 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008349"(MAP kinase kinase kinase kinase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSG00000135341(gene)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|ensembl:ENST00000369329(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017421(Mitogen-activated protein kinase kinase kinase 7)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27523N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:Q9NX58 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-713507|uniprotkb:Q6FI78|uniprotkb:Q9NYS1|ensembl:ENSP00000345917|ensembl:ENSP00000397367|uniprotkb:D3DVS4 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:lyar_human(display_long)|uniprotkb:LYAR(gene name)|psi-mi:LYAR(display_short)|uniprotkb:PNAS-5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 ensembl:ENSG00000145220(gene)|ensembl:ENST00000343470(transcript)|ensembl:ENST00000452476(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|interpro:IPR041010|mint:Q9NX58|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZVH|refseq:NP_001139197.1|refseq:NP_060286.1|refseq:XP_011511807.1|refseq:XP_011511808.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:AJ+5B1LahcUlSWQehJ2vxY+8pwY9606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:Q9Y248 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-747491|uniprotkb:Q6IAG9|uniprotkb:D3DUM5|ensembl:ENSP00000253462 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:psf2_human(display_long)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:GINS2(gene name)|psi-mi:GINS2(display_short)|uniprotkb:CGI-122(orf name)|uniprotkb:DC5(orf name)|uniprotkb:HSPC037(orf name)|uniprotkb:PSF2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 refseq:NP_057179.1|dip:DIP-29332N|ensembl:ENSG00000131153(gene)|ensembl:ENST00000253462(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|mint:Q9Y248|rcsb pdb:2E9X|rcsb pdb:2EHO|rcsb pdb:2Q9Q|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176974 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:OKFZLWhkmZNQxqS2tKptq61jsxs9606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:Q96G46 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-5458011|uniprotkb:Q96HM5|uniprotkb:Q9BSU4|uniprotkb:Q9H877|uniprotkb:Q9NPR1|ensembl:ENSP00000311977 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:dus3l_human(display_long)|uniprotkb:DUS3L(gene name)|psi-mi:DUS3L(display_short)|uniprotkb:tRNA-dihydrouridine synthase 3-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 refseq:NP_001155091.1|refseq:NP_064560.2|ensembl:ENSG00000141994(gene)|ensembl:ENST00000309061(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0017150"(tRNA dihydrouridine synthase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018517|interpro:IPR035587|interpro:IPR041367 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:WI70F8sJXWiIGEEuz+VUhZ3IjJs9606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:P01040 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:Q9NZN5 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 refseq:NP_001185594.1|refseq:NP_056128.1|refseq:NP_001288013.1|refseq:XP_011541022.1|refseq:XP_016872910.1|ensembl:ENST00000356641|ensembl:ENSP00000349056|ensembl:ENSP00000380942|dip:DIP-37887N|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|rcsb pdb:2OS6|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:O15085 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-311099|intact:EBI-28988539|ensembl:ENSP00000354644|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_055599.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_937879.1|ensembl:ENSP00000354644|ensembl:ENST00000368194|ensembl:ENSP00000357177|dip:DIP-31622N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PX9 uniprotkb:Q8N392 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-372814|uniprotkb:E1P575|uniprotkb:Q58EZ3|uniprotkb:Q6P679|uniprotkb:Q6PJD7|uniprotkb:Q96S64|intact:EBI-28984395|ensembl:ENSP00000357131 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:rhg18_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym)|uniprotkb:MacGAP(gene name synonym)|uniprotkb:ARHGAP18(gene name)|psi-mi:ARHGAP18(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409850|imex:IM-26436-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 refseq:NP_277050.2|ensembl:ENSP00000357131|ensembl:ENSG00000146376(gene)|ensembl:ENST00000368149(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:2000145"(regulation of cell motility) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:24F0Swg/Ye/UfWPt8fJcO+q0nkc9606 rigid:gTKogVlagqfpQX9o0kN5jCRE3q4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZPF3-1 uniprotkb:P46939 intact:EBI-25409810 intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515 psi-mi:q6zpf31(display_long)|uniprotkb:Tiam2(gene name)|psi-mi:Tiam2(display_short)|uniprotkb:Kiaa2016(gene name synonym)|uniprotkb:Stef(gene name synonym) psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409818|imex:IM-26436-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZPF3-1(isoform-parent) ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:C2rYxF1ueHUxa3i3TquIY83Nhqw10090 rogid:metWqbqGtzonNZ1mgNjlFrenuI89606 rigid:178nIZ7ZlVSVbDPuZgyI3nODPxM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZPF3-1 uniprotkb:Q13425 intact:EBI-25409810 intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09 psi-mi:q6zpf31(display_long)|uniprotkb:Tiam2(gene name)|psi-mi:Tiam2(display_short)|uniprotkb:Kiaa2016(gene name synonym)|uniprotkb:Stef(gene name synonym) psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409818|imex:IM-26436-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZPF3-1(isoform-parent) go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:C2rYxF1ueHUxa3i3TquIY83Nhqw10090 rogid:SABgmvArdLH93OpFobs/L3BleVY9606 rigid:178nIZ7ZlVSVbDPuZgyI3nODPxM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZPF3-1 uniprotkb:P28482 intact:EBI-25409810 intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64 psi-mi:q6zpf31(display_long)|uniprotkb:Tiam2(gene name)|psi-mi:Tiam2(display_short)|uniprotkb:Kiaa2016(gene name synonym)|uniprotkb:Stef(gene name synonym) psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409818|imex:IM-26436-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZPF3-1(isoform-parent) reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:C2rYxF1ueHUxa3i3TquIY83Nhqw10090 rogid:odzhd70I/8uWedx0+gF38lhe60I9606 rigid:178nIZ7ZlVSVbDPuZgyI3nODPxM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZPF3-1 uniprotkb:Q9Y4J8 intact:EBI-25409810 intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7 psi-mi:q6zpf31(display_long)|uniprotkb:Tiam2(gene name)|psi-mi:Tiam2(display_short)|uniprotkb:Kiaa2016(gene name synonym)|uniprotkb:Stef(gene name synonym) psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409818|imex:IM-26436-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZPF3-1(isoform-parent) ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:C2rYxF1ueHUxa3i3TquIY83Nhqw10090 rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606 rigid:178nIZ7ZlVSVbDPuZgyI3nODPxM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE6 uniprotkb:Q14157 intact:EBI-724864|uniprotkb:Q6P0L7|uniprotkb:Q8NAV5|uniprotkb:Q9NVT3|uniprotkb:Q17RW1|uniprotkb:Q3YFJ4|uniprotkb:Q5VXI5|uniprotkb:Q5VXI6|uniprotkb:Q66K51|uniprotkb:B7ZKS1|ensembl:ENSP00000355060 intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445 psi-mi:argal_human(display_long)|uniprotkb:GRINCHGEF(gene name synonym)|uniprotkb:KIAA1626(gene name synonym)|uniprotkb:GrinchGEF(gene name synonym)|uniprotkb:ARHGEF10L(gene name)|psi-mi:ARHGEF10L(display_short) psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409832|imex:IM-26436-206 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306766.1|refseq:NP_001306767.1|refseq:NP_001011722.2|refseq:NP_060595.3|ensembl:ENSG00000074964(gene)|ensembl:ENST00000361221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|refseq:NP_001315053.1|refseq:XP_005245982.2|refseq:XP_016857106.1|refseq:XP_016857110.1 refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HWnqkCHhpqMiOEwoYw8Uhfn8N+w9606 rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606 rigid:O2sGLfJB77OSP/FYT7V58ALM9NQ false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE6 uniprotkb:Q7Z6B7 intact:EBI-724864|uniprotkb:Q6P0L7|uniprotkb:Q8NAV5|uniprotkb:Q9NVT3|uniprotkb:Q17RW1|uniprotkb:Q3YFJ4|uniprotkb:Q5VXI5|uniprotkb:Q5VXI6|uniprotkb:Q66K51|uniprotkb:B7ZKS1|ensembl:ENSP00000355060 intact:EBI-2481729|uniprotkb:Q9H8A3|uniprotkb:Q9P2P2|ensembl:ENSP00000347198 psi-mi:argal_human(display_long)|uniprotkb:GRINCHGEF(gene name synonym)|uniprotkb:KIAA1626(gene name synonym)|uniprotkb:GrinchGEF(gene name synonym)|uniprotkb:ARHGEF10L(gene name)|psi-mi:ARHGEF10L(display_short) psi-mi:srgp1_human(display_long)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409832|imex:IM-26436-206 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306766.1|refseq:NP_001306767.1|refseq:NP_001011722.2|refseq:NP_060595.3|ensembl:ENSG00000074964(gene)|ensembl:ENST00000361221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|refseq:NP_001315053.1|refseq:XP_005245982.2|refseq:XP_016857106.1|refseq:XP_016857110.1 ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0030336"(negative regulation of cell migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|go:"GO:0005737"(cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|interpro:IPR037451|mint:Q7Z6B7|reactome:R-HSA-428543|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_065813.1|refseq:NP_001333130.1|dip:DIP-53826N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HWnqkCHhpqMiOEwoYw8Uhfn8N+w9606 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rigid:O2sGLfJB77OSP/FYT7V58ALM9NQ false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE6 uniprotkb:P62979 intact:EBI-724864|uniprotkb:Q6P0L7|uniprotkb:Q8NAV5|uniprotkb:Q9NVT3|uniprotkb:Q17RW1|uniprotkb:Q3YFJ4|uniprotkb:Q5VXI5|uniprotkb:Q5VXI6|uniprotkb:Q66K51|uniprotkb:B7ZKS1|ensembl:ENSP00000355060 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:argal_human(display_long)|uniprotkb:GRINCHGEF(gene name synonym)|uniprotkb:KIAA1626(gene name synonym)|uniprotkb:GrinchGEF(gene name synonym)|uniprotkb:ARHGEF10L(gene name)|psi-mi:ARHGEF10L(display_short) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409832|imex:IM-26436-206 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306766.1|refseq:NP_001306767.1|refseq:NP_001011722.2|refseq:NP_060595.3|ensembl:ENSG00000074964(gene)|ensembl:ENST00000361221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|refseq:NP_001315053.1|refseq:XP_005245982.2|refseq:XP_016857106.1|refseq:XP_016857110.1 reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HWnqkCHhpqMiOEwoYw8Uhfn8N+w9606 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 rigid:O2sGLfJB77OSP/FYT7V58ALM9NQ false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE6 uniprotkb:P33993 intact:EBI-724864|uniprotkb:Q6P0L7|uniprotkb:Q8NAV5|uniprotkb:Q9NVT3|uniprotkb:Q17RW1|uniprotkb:Q3YFJ4|uniprotkb:Q5VXI5|uniprotkb:Q5VXI6|uniprotkb:Q66K51|uniprotkb:B7ZKS1|ensembl:ENSP00000355060 intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288 psi-mi:argal_human(display_long)|uniprotkb:GRINCHGEF(gene name synonym)|uniprotkb:KIAA1626(gene name synonym)|uniprotkb:GrinchGEF(gene name synonym)|uniprotkb:ARHGEF10L(gene name)|psi-mi:ARHGEF10L(display_short) psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409832|imex:IM-26436-206 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306766.1|refseq:NP_001306767.1|refseq:NP_001011722.2|refseq:NP_060595.3|ensembl:ENSG00000074964(gene)|ensembl:ENST00000361221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|refseq:NP_001315053.1|refseq:XP_005245982.2|refseq:XP_016857106.1|refseq:XP_016857110.1 refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HWnqkCHhpqMiOEwoYw8Uhfn8N+w9606 rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606 rigid:O2sGLfJB77OSP/FYT7V58ALM9NQ false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE6 uniprotkb:Q9UMR2 intact:EBI-724864|uniprotkb:Q6P0L7|uniprotkb:Q8NAV5|uniprotkb:Q9NVT3|uniprotkb:Q17RW1|uniprotkb:Q3YFJ4|uniprotkb:Q5VXI5|uniprotkb:Q5VXI6|uniprotkb:Q66K51|uniprotkb:B7ZKS1|ensembl:ENSP00000355060 intact:EBI-719232|uniprotkb:Q6FIB7|uniprotkb:Q6IAE0|uniprotkb:Q9H0U0|uniprotkb:B3KNE9|ensembl:ENSP00000288071|uniprotkb:Q96KE7|uniprotkb:B4DXS6|uniprotkb:E7EMK4 psi-mi:argal_human(display_long)|uniprotkb:GRINCHGEF(gene name synonym)|uniprotkb:KIAA1626(gene name synonym)|uniprotkb:GrinchGEF(gene name synonym)|uniprotkb:ARHGEF10L(gene name)|psi-mi:ARHGEF10L(display_short) psi-mi:dd19b_human(display_long)|uniprotkb:DEAD box protein 19B(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD5(gene name synonym)|uniprotkb:DDX19B(gene name)|psi-mi:DDX19B(display_short)|uniprotkb:DBP5(gene name synonym)|uniprotkb:DDX19(gene name synonym)|uniprotkb:TDBP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409832|imex:IM-26436-206 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306766.1|refseq:NP_001306767.1|refseq:NP_001011722.2|refseq:NP_060595.3|ensembl:ENSG00000074964(gene)|ensembl:ENST00000361221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|refseq:NP_001315053.1|refseq:XP_005245982.2|refseq:XP_016857106.1|refseq:XP_016857110.1 refseq:NP_001014449.1|refseq:NP_001014451.1|refseq:NP_009173.1|ensembl:ENSG00000157349(gene)|ensembl:ENST00000288071(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:3EWS|rcsb pdb:3FHC|rcsb pdb:3FHT|rcsb pdb:3FMO|rcsb pdb:3FMP|rcsb pdb:3G0H|rcsb pdb:6B4I|rcsb pdb:6B4J|rcsb pdb:6B4K|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_001244102.1|refseq:NP_001244103.1|refseq:NP_001244101.1|dip:DIP-48486N|refseq:XP_006721190.1|refseq:XP_016878379.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HWnqkCHhpqMiOEwoYw8Uhfn8N+w9606 rogid:1UiDyTWXtMNt5s6Dw86KD1xY+0o9606 rigid:O2sGLfJB77OSP/FYT7V58ALM9NQ false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HCE6 uniprotkb:P48444 intact:EBI-724864|uniprotkb:Q6P0L7|uniprotkb:Q8NAV5|uniprotkb:Q9NVT3|uniprotkb:Q17RW1|uniprotkb:Q3YFJ4|uniprotkb:Q5VXI5|uniprotkb:Q5VXI6|uniprotkb:Q66K51|uniprotkb:B7ZKS1|ensembl:ENSP00000355060 intact:EBI-1044491|ensembl:ENSP00000264028|uniprotkb:Q52M80|uniprotkb:B4E1X2|uniprotkb:E9PEU4 psi-mi:argal_human(display_long)|uniprotkb:GRINCHGEF(gene name synonym)|uniprotkb:KIAA1626(gene name synonym)|uniprotkb:GrinchGEF(gene name synonym)|uniprotkb:ARHGEF10L(gene name)|psi-mi:ARHGEF10L(display_short) psi-mi:copd_human(display_long)|uniprotkb:Delta-coat protein(gene name synonym)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:COPD(gene name synonym)|uniprotkb:Archain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409832|imex:IM-26436-206 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306766.1|refseq:NP_001306767.1|refseq:NP_001011722.2|refseq:NP_060595.3|ensembl:ENSG00000074964(gene)|ensembl:ENST00000361221(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039919|refseq:NP_001315053.1|refseq:XP_005245982.2|refseq:XP_016857106.1|refseq:XP_016857110.1 ensembl:ENSG00000095139(gene)|ensembl:ENST00000264028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:P48444|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001135753.1|refseq:NP_001646.2|dip:DIP-50375N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:HWnqkCHhpqMiOEwoYw8Uhfn8N+w9606 rogid:67dTqyFC/zHDlTapW36OMyXbz0M9606 rigid:O2sGLfJB77OSP/FYT7V58ALM9NQ false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q66T02-1 uniprotkb:Q6PK04 intact:EBI-9079984|ensembl:ENSMUSP00000101286 intact:EBI-714654|ensembl:ENSP00000329360|ensembl:ENSP00000458884 psi-mi:q66t02-1(display_long)|uniprotkb:SYX1(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:cc137_human(display_long)|uniprotkb:CCDC137(gene name)|psi-mi:CCDC137(display_short)|uniprotkb:cPERP-B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409900|imex:IM-26436-124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9079953(isoform-parent)|uniprotkb:Q66T02-1(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000105661(transcript) refseq:NP_954981.1|ensembl:ENSG00000185298(gene)|ensembl:ENST00000329214(transcript)|ensembl:ENST00000575223(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR026680|mint:Q6PK04 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:R3+p5/EaPub0slhY5cYxBK1eMIE10090 rogid:e64Y/4oJpFqmYZEO1lOUHeLwy0I9606 rigid:CCf3wUvy3FM4vo59j0/+lMzDYxk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q66T02-1 uniprotkb:O75947 intact:EBI-9079984|ensembl:ENSMUSP00000101286 intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6 psi-mi:q66t02-1(display_long)|uniprotkb:SYX1(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409900|imex:IM-26436-124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9079953(isoform-parent)|uniprotkb:Q66T02-1(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000105661(transcript) refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:R3+p5/EaPub0slhY5cYxBK1eMIE10090 rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606 rigid:CCf3wUvy3FM4vo59j0/+lMzDYxk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q66T02-1 uniprotkb:P61586 intact:EBI-9079984|ensembl:ENSMUSP00000101286 intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175|ensembl:ENSP00000408402|ensembl:ENSP00000503282|ensembl:ENSP00000504180 psi-mi:q66t02-1(display_long)|uniprotkb:SYX1(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409900|imex:IM-26436-124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9079953(isoform-parent)|uniprotkb:Q66T02-1(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000105661(transcript) refseq:NP_001655.1|refseq:NP_001300870.1|dip:DIP-29642N|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|rcsb pdb:3LW8|ensembl:ENSG00000067560(gene)|ensembl:ENST00000418115(transcript)|ensembl:ENST00000445425(transcript)|ensembl:ENST00000678200(transcript)|ensembl:ENST00000679208(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007015"(actin filament organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0017022"(myosin binding)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0001998"(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033688"(regulation of osteoblast proliferation)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0002363"(alpha-beta T cell lineage commitment)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043366"(beta selection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060193"(positive regulation of lipase activity)|go:"GO:0061383"(trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902766"(skeletal muscle satellite cell migration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904695"(positive regulation of vascular associated smooth muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:2RGN|rcsb pdb:3KZ1|go:"GO:0050919"(negative chemotaxis) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:R3+p5/EaPub0slhY5cYxBK1eMIE10090 rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606 rigid:CCf3wUvy3FM4vo59j0/+lMzDYxk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q66T02-1 uniprotkb:O75970 intact:EBI-9079984|ensembl:ENSMUSP00000101286 intact:EBI-821405|intact:EBI-2684724|uniprotkb:Q4LE30|uniprotkb:B7ZMI4|uniprotkb:A6NLC2|uniprotkb:O43798|uniprotkb:Q5CZ80|uniprotkb:Q5JTX3|uniprotkb:Q5JTX6|uniprotkb:Q5JTX7|uniprotkb:Q5JUC3|uniprotkb:Q5JUC4|uniprotkb:Q5VZ62|uniprotkb:Q8N790|intact:EBI-10961605|uniprotkb:B2RTS3|ensembl:ENSP00000320006 psi-mi:q66t02-1(display_long)|uniprotkb:SYX1(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:mpdz_human(display_long)|uniprotkb:Multi-PDZ domain protein 1(gene name synonym)|uniprotkb:MPDZ(gene name)|psi-mi:MPDZ(display_short)|uniprotkb:MUPP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409900|imex:IM-26436-124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9079953(isoform-parent)|uniprotkb:Q66T02-1(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000105661(transcript) refseq:XP_006716948.1|refseq:XP_006716949.1|refseq:XP_006716950.1|refseq:XP_006716951.1|refseq:XP_006716952.1|refseq:XP_006716954.1|refseq:NP_003820.2|refseq:NP_001248335.1|refseq:NP_001248336.1|refseq:NP_001317566.1|refseq:XP_016870742.1|ensembl:ENSG00000107186(gene)|ensembl:ENST00000319217(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030425"(dendrite)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR032078|interpro:IPR036034|interpro:IPR036892|mint:O75970|rcsb pdb:2FCF|rcsb pdb:2FNE|rcsb pdb:2IWN|rcsb pdb:2IWO|rcsb pdb:2IWP|rcsb pdb:2IWQ|rcsb pdb:2O2T|rcsb pdb:2OPG|rcsb pdb:2QG1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:R3+p5/EaPub0slhY5cYxBK1eMIE10090 rogid:Q5QzIDHLoL/sWqQI7r/Kb4VLSdY9606 rigid:CCf3wUvy3FM4vo59j0/+lMzDYxk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q66T02-1 uniprotkb:Q9NUP9 intact:EBI-9079984|ensembl:ENSMUSP00000101286 intact:EBI-1171517|ensembl:ENSP00000278193 psi-mi:q66t02-1(display_long)|uniprotkb:SYX1(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409900|imex:IM-26436-124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9079953(isoform-parent)|uniprotkb:Q66T02-1(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000105661(transcript) refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:R3+p5/EaPub0slhY5cYxBK1eMIE10090 rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606 rigid:CCf3wUvy3FM4vo59j0/+lMzDYxk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q66T02-1 uniprotkb:Q8NI35 intact:EBI-9079984|ensembl:ENSMUSP00000101286 intact:EBI-724390|uniprotkb:O15249|uniprotkb:O43742|uniprotkb:O60833|uniprotkb:Q5VUA5|uniprotkb:Q5VUA6|uniprotkb:Q5VUA7|uniprotkb:Q5VUA8|uniprotkb:Q5VUA9|uniprotkb:Q5VUB0|uniprotkb:Q8WU78|uniprotkb:Q9H3N9|ensembl:ENSP00000360200 psi-mi:q66t02-1(display_long)|uniprotkb:SYX1(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:inadl_human(display_long)|uniprotkb:CIPP(gene name synonym)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:PATJ(gene name)|psi-mi:PATJ(display_short)|uniprotkb:INADL(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409900|imex:IM-26436-124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9079953(isoform-parent)|uniprotkb:Q66T02-1(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000105661(transcript) ensembl:ENSP00000360200|ensembl:ENST00000484937|ensembl:ENSP00000433669|ensembl:ENSG00000132849(gene)|ensembl:ENST00000371158(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q8NI35|rcsb pdb:1VF6|rcsb pdb:2D92|rcsb pdb:2DAZ|rcsb pdb:2DB5|rcsb pdb:2DLU|rcsb pdb:2DM8|rcsb pdb:2DMZ|rcsb pdb:2EHR|rcsb pdb:4Q2N|rcsb pdb:6IRD|reactome:R-HSA-420029 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:R3+p5/EaPub0slhY5cYxBK1eMIE10090 rogid:brzBKZb3r39w13Ds5X/1jB6YMyM9606 rigid:CCf3wUvy3FM4vo59j0/+lMzDYxk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q66T02-1 uniprotkb:O14908 intact:EBI-9079984|ensembl:ENSMUSP00000101286 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 psi-mi:q66t02-1(display_long)|uniprotkb:SYX1(isoform synonym)|uniprotkb:Plekhg5(gene name)|psi-mi:Plekhg5(display_short)|uniprotkb:Kiaa0720(gene name synonym)|uniprotkb:Syx(gene name synonym)|uniprotkb:Synectin-binding RhoA exchange factor(gene name synonym) psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409900|imex:IM-26436-124 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-9079953(isoform-parent)|uniprotkb:Q66T02-1(isoform-parent)|ensembl:ENSMUSG00000039713(gene)|ensembl:ENSMUST00000105661(transcript) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:R3+p5/EaPub0slhY5cYxBK1eMIE10090 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rigid:CCf3wUvy3FM4vo59j0/+lMzDYxk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P97924-3 uniprotkb:P15882 intact:EBI-25409920 intact:EBI-718947|uniprotkb:B3KNU6|uniprotkb:Q53SD6|uniprotkb:Q53SH5|uniprotkb:Q96FB0|uniprotkb:A8K1M6|uniprotkb:B4DV19|ensembl:ENSP00000386741 psi-mi:p97924-3(display_long)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)|uniprotkb:Duo(gene name synonym)|uniprotkb:Hapip(gene name synonym)|uniprotkb:Huntingtin-associated protein-interacting protein(gene name synonym)|uniprotkb:PAM COOH-terminal interactor protein 10(gene name synonym)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalirin-8A(isoform synonym)|uniprotkb:P-CIP10A(isoform synonym) psi-mi:chin_human(display_long)|uniprotkb:N-chimerin(gene name synonym)|uniprotkb:Alpha-chimerin(gene name synonym)|uniprotkb:A-chimaerin(gene name synonym)|uniprotkb:Rho GTPase-activating protein 2(gene name synonym)|uniprotkb:CHN1(gene name)|psi-mi:CHN1(display_short)|uniprotkb:ARHGAP2(gene name synonym)|uniprotkb:CHN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409930|imex:IM-26436-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1397166(isoform-parent) refseq:NP_001020372.2|refseq:NP_001193531.1|refseq:NP_001813.1|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR017356(N-chimaerin)|interpro:IPR020454|interpro:IPR035840|interpro:IPR036860|interpro:IPR037860|mint:P15882|rcsb pdb:2OSA|rcsb pdb:3CXL|reactome:R-HSA-9013148|reactome:R-HSA-9013149|ensembl:ENSG00000128656(gene)|ensembl:ENST00000409900(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|dip:DIP-42177N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:kZhx6gaBJz7NY1VPyOPYWvaW0j010116 rogid:84hAAd7YQd4QiItoC14jdT4CnRU9606 rigid:D3XNSuByu3wb9oJaZj+7n/Xksms false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P97924-3 uniprotkb:O43307 intact:EBI-25409920 intact:EBI-3447299|uniprotkb:Q5JSL6|uniprotkb:A8K1S8|uniprotkb:B4DHC7|intact:EBI-28976942|ensembl:ENSP00000253401|ensembl:ENSP00000500829|uniprotkb:F8W7P8 psi-mi:p97924-3(display_long)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)|uniprotkb:Duo(gene name synonym)|uniprotkb:Hapip(gene name synonym)|uniprotkb:Huntingtin-associated protein-interacting protein(gene name synonym)|uniprotkb:PAM COOH-terminal interactor protein 10(gene name synonym)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalirin-8A(isoform synonym)|uniprotkb:P-CIP10A(isoform synonym) psi-mi:arhg9_human(display_long)|uniprotkb:ARHGEF9(gene name)|psi-mi:ARHGEF9(display_short)|uniprotkb:KIAA0424(gene name synonym)|uniprotkb:Collybistin(gene name synonym)|uniprotkb:PEM-2 homolog(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 9(gene name synonym)|uniprotkb:ARHDH9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409930|imex:IM-26436-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1397166(isoform-parent) ensembl:ENSP00000253401|ensembl:ENST00000623517|ensembl:ENSP00000485369|ensembl:ENST00000624843|ensembl:ENSP00000485626|ensembl:ENSP00000500829|refseq:NP_001166950.1|refseq:NP_001166951.1|refseq:NP_056000.1|ensembl:ENSG00000131089(gene)|ensembl:ENST00000253401(transcript)|ensembl:ENST00000671907(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035728|interpro:IPR035899|interpro:IPR036028|rcsb pdb:2YSQ|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-977443|refseq:XP_016884855.1|refseq:XP_016884862.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:kZhx6gaBJz7NY1VPyOPYWvaW0j010116 rogid:fNeHhwbyPWGv+2Iak2k7AE/gDd49606 rigid:D3XNSuByu3wb9oJaZj+7n/Xksms false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P97924-3 uniprotkb:Q15052 intact:EBI-25409920 intact:EBI-1642523|uniprotkb:A6NMW9|uniprotkb:A8K6S7|uniprotkb:Q15396|uniprotkb:Q5JQ66|uniprotkb:Q7Z3W1|uniprotkb:Q86XH0|uniprotkb:B1AL37|ensembl:ENSP00000250617 psi-mi:p97924-3(display_long)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)|uniprotkb:Duo(gene name synonym)|uniprotkb:Hapip(gene name synonym)|uniprotkb:Huntingtin-associated protein-interacting protein(gene name synonym)|uniprotkb:PAM COOH-terminal interactor protein 10(gene name synonym)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalirin-8A(isoform synonym)|uniprotkb:P-CIP10A(isoform synonym) psi-mi:arhg6_human(display_long)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409930|imex:IM-26436-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1397166(isoform-parent) refseq:NP_001293106.1|refseq:NP_004831.1|dip:DIP-42694N|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003096(SM22/calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR032409|interpro:IPR035788|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q15052|rcsb pdb:1UJY|rcsb pdb:1WYR|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-446388|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:kZhx6gaBJz7NY1VPyOPYWvaW0j010116 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rigid:D3XNSuByu3wb9oJaZj+7n/Xksms false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P97924-3 uniprotkb:Q9P227 intact:EBI-25409920 intact:EBI-20721052|ensembl:ENSP00000479208|ensembl:ENSP00000481862 psi-mi:p97924-3(display_long)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)|uniprotkb:Duo(gene name synonym)|uniprotkb:Hapip(gene name synonym)|uniprotkb:Huntingtin-associated protein-interacting protein(gene name synonym)|uniprotkb:PAM COOH-terminal interactor protein 10(gene name synonym)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalirin-8A(isoform synonym)|uniprotkb:P-CIP10A(isoform synonym) psi-mi:rhg23_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 23(gene name synonym)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409930|imex:IM-26436-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1397166(isoform-parent) ensembl:ENSG00000273780(gene)|ensembl:ENSG00000275832(gene)|ensembl:ENST00000610551(transcript)|ensembl:ENST00000622683(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000198(RhoGAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR041489|interpro:IPR041681|reactome:R-HSA-8980692|reactome:R-HSA-9013149|refseq:NP_001186346.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:kZhx6gaBJz7NY1VPyOPYWvaW0j010116 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rigid:D3XNSuByu3wb9oJaZj+7n/Xksms false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:Q14011 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-538850|uniprotkb:B4E2X2|intact:EBI-10980353|uniprotkb:B3KT17|ensembl:ENSP00000322887|ensembl:ENSP00000465779|ensembl:ENSP00000466110|ensembl:ENSP00000466207|ensembl:ENSP00000468788 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:cirbp_human(display_long)|uniprotkb:Glycine-rich RNA-binding protein CIRP(gene name synonym)|uniprotkb:A18 hnRNP(gene name synonym)|uniprotkb:CIRBP(gene name)|psi-mi:CIRBP(display_short)|uniprotkb:A18HNRNP(gene name synonym)|uniprotkb:CIRP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_001271.1|refseq:XP_006722700.1|refseq:NP_001287744.1|refseq:NP_001287758.1|ensembl:ENSG00000099622(gene)|ensembl:ENST00000320936(transcript)|ensembl:ENST00000585630(transcript)|ensembl:ENST00000586472(transcript)|ensembl:ENST00000588030(transcript)|ensembl:ENST00000588090(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009409"(response to cold)|go:"GO:0009411"(response to UV)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030371"(translation repressor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|mint:Q14011|rcsb pdb:1X5S|rcsb pdb:5TBX - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:nm6/8k5Pw1AnoXsSw9cazJkL49U9606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:O15027 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:Q86U42 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:P14373 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-719493|uniprotkb:A2BE15|uniprotkb:Q5RJA8|uniprotkb:Q5ST26|uniprotkb:Q6LA73|uniprotkb:Q6NXR9|uniprotkb:Q9BZY6|uniprotkb:Q9UJL3|ensembl:ENSP00000383555|ensembl:ENSP00000392787|ensembl:ENSP00000405229|ensembl:ENSP00000414793|ensembl:ENSP00000366404 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:tri27_human(display_long)|uniprotkb:TRIM27(gene name)|psi-mi:TRIM27(display_short)|uniprotkb:RNF76(gene name synonym)|uniprotkb:RFP(gene name synonym)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:RING finger protein 76(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_006501.1|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:P14373|reactome:R-HSA-3232142|reactome:R-HSA-9635465|reactome:R-HSA-8948751|ensembl:ENSG00000204713(gene)|ensembl:ENSG00000215641(gene)|ensembl:ENSG00000229006(gene)|ensembl:ENSG00000234495(gene)|ensembl:ENSG00000237071(gene)|ensembl:ENST00000377199(transcript)|ensembl:ENST00000400720(transcript)|ensembl:ENST00000431123(transcript)|ensembl:ENST00000435528(transcript)|ensembl:ENST00000437160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016605"(PML body)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic) - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:dsfH5OUghD8KSaTz1SFw9OYVTK49606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:Q15293 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-948278|ensembl:ENSP00000054950|uniprotkb:D3DR00|uniprotkb:B7Z1M1 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:rcn1_human(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:RCN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) reactome:R-HSA-8957275|reactome:R-HSA-381426|ensembl:ENSG00000049449(gene)|ensembl:ENST00000054950(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q15293|refseq:NP_002892.1 - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:ynhvrXX2fQ7Dn1LT+mp2PKm0bc89606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:O00743 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005 - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:P51608 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:Q9C005 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:P33240 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-711360|uniprotkb:Q5H951|uniprotkb:Q6LA74|uniprotkb:Q8N502|ensembl:ENSP00000362063 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:cstf2_human(display_long)|uniprotkb:CSTF2(gene name)|psi-mi:CSTF2(display_short)|uniprotkb:CF-1 64 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 64 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_001293138.1|ensembl:ENSG00000101811(gene)|ensembl:ENST00000372972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016604"(nuclear body)|go:"GO:0071920"(cleavage body)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025742|interpro:IPR026896|interpro:IPR033105|interpro:IPR035979|interpro:IPR038192|mint:P33240|rcsb pdb:1P1T|rcsb pdb:2J8P|rcsb pdb:6Q2I|rcsb pdb:6TZE|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001316.1|dip:DIP-36129N - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:oZ/4DPJOEWflU05127TEp+ezQi89606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z5H3-2 uniprotkb:O43852 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409874|imex:IM-26436-312 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1 - isoform-comment:No experimental confirmation available. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606 rigid:3tzRKwxif6JLN4dkoKewX7GmFM8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q8N726 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-625922|uniprotkb:Q13195|uniprotkb:Q13399|uniprotkb:Q16360|uniprotkb:Q7KZR9|ensembl:ENSP00000432664|ensembl:ENSP00000462950|uniprotkb:D3DRK2 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:arf_human(display_long)|uniprotkb:p14ARF(gene name synonym)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:MLM(gene name synonym)|uniprotkb:Alternative reading frame(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) ensembl:ENSG00000147889(gene)|ensembl:ENST00000530628(transcript)|ensembl:ENST00000579755(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0050821"(protein stabilization)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0055105"(ubiquitin-protein transferase inhibitor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090398"(cellular senescence)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR010868(Cyclin-dependent kinase inhibitor 2a p19Arf, N-terminal)|mint:Q8N726|reactome:R-HSA-111471|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-6804757|reactome:R-HSA-69541|reactome:R-HSA-8941858|reactome:R-HSA-9645722|reactome:R-HSA-9646303|reactome:R-HSA-9646304|refseq:NP_478102.2|dip:DIP-24171N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:zdbvJmkrI/zJFL+Enq5jTM1Csdw9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:P13667 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:A5D8V6 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-2559305|uniprotkb:Q8N3K4|ensembl:ENSP00000301765 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:vp37c_human(display_long)|uniprotkb:VPS37C(gene name)|psi-mi:VPS37C(display_short)|uniprotkb:PML39(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS37C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_060436.4|ensembl:ENSG00000167987(gene)|ensembl:ENST00000301765(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:A5D8V6|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|refseq:XP_005274134.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:PC6LXCxyACN78OdaFHSvWhz6tMY9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q93009 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q9P270 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-3959887|uniprotkb:A8K4P1|uniprotkb:Q8N5R3|ensembl:ENSP00000264313 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:slai2_human(display_long)|uniprotkb:SLAIN2(gene name)|psi-mi:SLAIN2(display_short)|uniprotkb:KIAA1458(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_065897.1|ensembl:ENSG00000109171(gene)|ensembl:ENST00000264313(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR026179|mint:Q9P270|rcsb pdb:3RDV - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:r8OlU6BASEpehSYkbA9b3F3q5go9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:P46060 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:P30044 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-722161|uniprotkb:Q14CK0|uniprotkb:Q6IAF2|uniprotkb:Q9UBU5|uniprotkb:Q9UJU4|uniprotkb:Q9UKX4|uniprotkb:A6NG06|uniprotkb:B7ZLJ4|uniprotkb:A6NC19|uniprotkb:B7ZVW3|ensembl:ENSP00000265462 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:prdx5_human(display_long)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:TPx type VI(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 71B(gene name synonym)|uniprotkb:Alu corepressor 1(gene name synonym)|uniprotkb:PRDX5(gene name)|psi-mi:PRDX5(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)|uniprotkb:SBBI10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_036226.1|refseq:NP_857634.1|refseq:NP_857635.1|ensembl:ENSG00000126432(gene)|ensembl:ENST00000265462(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037944|mint:P30044|rcsb pdb:1H4O|rcsb pdb:1HD2|rcsb pdb:1OC3|rcsb pdb:1URM|rcsb pdb:2VL2|rcsb pdb:2VL3|rcsb pdb:2VL9|rcsb pdb:3MNG|rcsb pdb:4K7I|rcsb pdb:4K7N|rcsb pdb:4K7O|rcsb pdb:4MMM|reactome:R-HSA-3299685|reactome:R-HSA-5628897 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:Z1fs04RUXWI7z+s7Y+hzGige4mU9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q13177 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-1045887|uniprotkb:Q13154|uniprotkb:Q6ISC3|ensembl:ENSP00000314067|intact:EBI-28976120 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:pak2_human(display_long)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:PAK65(gene name synonym)|uniprotkb:S6/H4 kinase(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) ensembl:ENSP00000314067|ensembl:ENSG00000180370(gene)|ensembl:ENST00000327134(transcript)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035064|interpro:IPR035065|interpro:IPR036936|mint:Q13177|rcsb pdb:3PCS|reactome:R-HSA-164944|reactome:R-HSA-202433|reactome:R-HSA-211728|reactome:R-HSA-211733|reactome:R-HSA-211736|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-445355|reactome:R-HSA-5621575|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-5218920|refseq:NP_002568.2|refseq:XP_011511172.1|refseq:XP_016861990.1|dip:DIP-38249N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:BLFG1UZy6GUy26Hd7VDehsIq3/I9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q13153 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-1307|uniprotkb:O75561|uniprotkb:Q13567|uniprotkb:Q32M53|uniprotkb:Q32M54|uniprotkb:Q86W79|intact:EBI-28976107|ensembl:ENSP00000348696 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:pak1_human(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_001122092.1|refseq:NP_002567.3|ensembl:ENST00000278568|ensembl:ENSP00000278568|ensembl:ENSP00000348696|go:"GO:0001666"(response to hypoxia)|go:"GO:0001726"(ruffle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|refseq:XP_011543382.1|refseq:XP_011543383.1|refseq:XP_011543384.1|refseq:XP_011543385.1|refseq:XP_011543386.1|refseq:XP_016873335.1|refseq:XP_016873336.1|refseq:XP_016873337.1|refseq:XP_016873338.1|refseq:XP_016873339.1|dip:DIP-31016N|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:Q13153|rcsb pdb:1F3M|rcsb pdb:1YHV|rcsb pdb:1YHW|rcsb pdb:1ZSG|rcsb pdb:2HY8|rcsb pdb:2QME|rcsb pdb:3DVP|rcsb pdb:3FXZ|rcsb pdb:3FY0|rcsb pdb:3Q4Z|rcsb pdb:3Q52|rcsb pdb:3Q53|rcsb pdb:4DAW|rcsb pdb:4EQC|rcsb pdb:4O0R|rcsb pdb:4O0T|rcsb pdb:4P90|rcsb pdb:4ZJI|rcsb pdb:4ZJJ|rcsb pdb:4ZLO|rcsb pdb:4ZY4|rcsb pdb:4ZY5|rcsb pdb:4ZY6|rcsb pdb:5DEW|rcsb pdb:5DEY|rcsb pdb:5DFP|rcsb pdb:5IME|rcsb pdb:5KBQ|rcsb pdb:5KBR|rcsb pdb:6B16|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-2871796|reactome:R-HSA-376172|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-445144|reactome:R-HSA-445355|reactome:R-HSA-5218920|reactome:R-HSA-5621575|reactome:R-HSA-5625740|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:P68871 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-715554|ensembl:ENSP00000333994|ensembl:ENSP00000494175|uniprotkb:P02023|uniprotkb:Q13852|uniprotkb:Q14481|uniprotkb:Q14510|uniprotkb:Q45KT0|uniprotkb:Q6FI08|uniprotkb:Q8IZI1|uniprotkb:Q9BX96|uniprotkb:Q9UCP8|uniprotkb:Q9UCP9|uniprotkb:A4GX73|uniprotkb:B2ZUE0|uniprotkb:Q549N7|uniprotkb:Q6R7N2|uniprotkb:Q9UCD6 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:hbb_human(display_long)|uniprotkb:Hemoglobin beta chain(gene name synonym)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) ensembl:ENSG00000244734(gene)|ensembl:ENST00000335295(transcript)|ensembl:ENST00000647020(transcript)|refseq:NP_000509.1|rcsb pdb:1XZ4|rcsb pdb:1XZ2|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YZI|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:1YVT|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3HXN|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P68871|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|go:"GO:0072562"(blood microparticle)|rcsb pdb:1A3O|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CBL|rcsb pdb:1CBM|rcsb pdb:1CH4|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1J3Z|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-6798695|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-983231|rcsb pdb:7JY3|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:3W4U|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6FQF|rcsb pdb:6HAL|rcsb pdb:4ROM|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|dip:DIP-35526N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:Y5tl4dXE3PBfaK/0lROD6QJ4U+c9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:P69905 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-714680|uniprotkb:P01922|ensembl:ENSP00000251595|ensembl:ENSP00000322421|uniprotkb:Q3MIF5|uniprotkb:Q96KF1|uniprotkb:Q9NYR7|uniprotkb:Q1HDT5|uniprotkb:Q53F97|uniprotkb:Q9UCM0 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:hba_human(display_long)|uniprotkb:Hemoglobin alpha chain(gene name synonym)|uniprotkb:Alpha-globin(gene name synonym)|uniprotkb:HBA1(gene name)|psi-mi:HBA1(display_short)|uniprotkb:HBA2(gene name)|psi-mi:HBA2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) ensembl:ENSG00000188536(gene)|ensembl:ENSG00000206172(gene)|ensembl:ENST00000251595(transcript)|ensembl:ENST00000320868(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015671"(oxygen transport)|go:"GO:0016020"(membrane)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P69905|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|rcsb pdb:1A3O|rcsb pdb:1A9W|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FDH|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1YVQ|rcsb pdb:1YVT|rcsb pdb:1YZI|rcsb pdb:1Z8U|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3HXN|rcsb pdb:3IA3|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3OVU|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S48|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4MQJ|rcsb pdb:4MQK|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6HAL|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:4N7N|rcsb pdb:6KAU|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:6KAV|rcsb pdb:4N8T|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:4NI0|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4ROM|rcsb pdb:4WJG|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEV|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|rcsb pdb:7JY3|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:7AEU|refseq:NP_000508.1|refseq:NP_000549.1|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J3Z|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1SHR|rcsb pdb:1SI4|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|rcsb pdb:1XZ2|rcsb pdb:1XZ4|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y01|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|dip:DIP-35199N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:M4o0FF1DIrouBdyFXr4UtAlcjZw9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q14161 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-1046878|uniprotkb:Q86U59|uniprotkb:Q96CI2|uniprotkb:Q9BV91|uniprotkb:Q9Y5V2|ensembl:ENSP00000347464 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:git2_human(display_long)|uniprotkb:G protein-coupled receptor kinase-interactor 2(gene name synonym)|uniprotkb:GRK-interacting protein 2(gene name synonym)|uniprotkb:Cool-interacting tyrosine-phosphorylated protein 2(gene name synonym)|uniprotkb:GIT2(gene name)|psi-mi:GIT2(display_short)|uniprotkb:KIAA0148(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) ensembl:ENSG00000139436(gene)|ensembl:ENST00000355312(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR020683|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|refseq:NP_001128685.1|refseq:NP_001128686.1|refseq:NP_055591.2|refseq:NP_476510.1|refseq:NP_476511.1|refseq:XP_006719770.1|refseq:XP_006719772.1|refseq:NP_001317082.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:Zy6G7UFDxfCVVUEHq44V37dWekw9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q9Y2X7 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-466061|uniprotkb:Q86SS0|uniprotkb:Q9BRJ4|uniprotkb:B4DSV3|ensembl:ENSP00000225394|uniprotkb:B4DGU9 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:git1_human(display_long)|uniprotkb:GIT1(gene name)|psi-mi:GIT1(display_short)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:p95-APP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_001078923.1|refseq:NP_054749.2|ensembl:ENSG00000108262(gene)|ensembl:ENST00000225394(transcript)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045820"(negative regulation of glycolytic process)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|go:"GO:0046872"(metal ion binding)|interpro:IPR020683|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|go:"GO:0048666"(neuron development)|go:"GO:0061743"(motor learning)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0106015"(negative regulation of inflammatory response to wounding)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR038508|interpro:IPR001164(Arf GTPase activating protein)|mint:Q9Y2X7|interpro:IPR002110(Ankyrin)|reactome:R-HSA-3928664|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9619229 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:9POm+EVvD4/BQh6bApnpXCAZyZo9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q9NVF7 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-740282|uniprotkb:O75070|ensembl:ENSP00000355827|uniprotkb:E9PEM8 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:fbx28_human(display_long)|uniprotkb:FBXO28(gene name)|psi-mi:FBXO28(display_short)|uniprotkb:KIAA0483(gene name synonym)|uniprotkb:CENP-30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_055991.1|ensembl:ENSG00000143756(gene)|ensembl:ENST00000366862(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0042802"(identical protein binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR036047|interpro:IPR039719|refseq:NP_001129587.1|dip:DIP-56683N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:Iz7yI5ugv60KqYH7MAdBjXjw2vs9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:O43307 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-3447299|uniprotkb:Q5JSL6|uniprotkb:A8K1S8|uniprotkb:B4DHC7|intact:EBI-28976942|ensembl:ENSP00000253401|ensembl:ENSP00000500829|uniprotkb:F8W7P8 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:arhg9_human(display_long)|uniprotkb:ARHGEF9(gene name)|psi-mi:ARHGEF9(display_short)|uniprotkb:KIAA0424(gene name synonym)|uniprotkb:Collybistin(gene name synonym)|uniprotkb:PEM-2 homolog(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 9(gene name synonym)|uniprotkb:ARHDH9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) ensembl:ENSP00000253401|ensembl:ENST00000623517|ensembl:ENSP00000485369|ensembl:ENST00000624843|ensembl:ENSP00000485626|ensembl:ENSP00000500829|refseq:NP_001166950.1|refseq:NP_001166951.1|refseq:NP_056000.1|ensembl:ENSG00000131089(gene)|ensembl:ENST00000253401(transcript)|ensembl:ENST00000671907(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035728|interpro:IPR035899|interpro:IPR036028|rcsb pdb:2YSQ|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-977443|refseq:XP_016884855.1|refseq:XP_016884862.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:fNeHhwbyPWGv+2Iak2k7AE/gDd49606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q14155 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-717515|uniprotkb:B1ALK6|uniprotkb:B1ALK8|uniprotkb:Q3LIA4|uniprotkb:Q5W9H0|uniprotkb:Q6P9G3|uniprotkb:Q6PII2|uniprotkb:Q86W63|uniprotkb:Q8N3M1|ensembl:ENSP00000364893 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:arhg7_human(display_long)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) refseq:NP_001307782.1|refseq:NP_663788.1|refseq:NP_001106983.1|refseq:NP_001106984.1|refseq:NP_001106985.1|refseq:NP_001307780.1|refseq:NP_001307783.1|refseq:NP_001317526.1|refseq:NP_001317527.1|ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0005925"(focal adhesion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1904424"(regulation of GTP binding)|go:"GO:1905833"(negative regulation of microtubule nucleation)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035789|interpro:IPR035899|interpro:IPR036028|interpro:IPR036872|mint:Q14155|rcsb pdb:1BY1|rcsb pdb:1ZSG|rcsb pdb:2L3G|rcsb pdb:5SXP|reactome:R-HSA-182971|reactome:R-HSA-193648|reactome:R-HSA-3928664|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9619229|dip:DIP-40794N|refseq:NP_003890.1|refseq:XP_016876313.1|refseq:XP_016876314.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15052-1 uniprotkb:Q17R89 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-720416|uniprotkb:Q9Y4Q4|uniprotkb:A8MQB2|uniprotkb:O75160|uniprotkb:Q7Z5Z7|uniprotkb:A6NCP5|ensembl:ENSP00000368994 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:rhg44_human(display_long)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)|uniprotkb:NPC-A-10(gene name synonym)|uniprotkb:ARHGAP44(gene name)|psi-mi:ARHGAP44(display_short)|uniprotkb:KIAA0672(gene name synonym)|uniprotkb:RICH2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409952|imex:IM-26436-170 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) mint:Q17R89|refseq:NP_055674.4|ensembl:ENSG00000006740(gene)|ensembl:ENST00000379672(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035021"(negative regulation of Rac protein signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0055037"(recycling endosome)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098886"(modification of dendritic spine)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR004148(BAR)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|refseq:NP_001308095.1|refseq:NP_001308097.1|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:gN2xiWHjD8x8sIV6o2YJV+/RRSQ9606 rigid:r5T59VodHLNXvGF7nmbqfL93UJ8 false tag:n-n|mutation:1-3 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13017-1 uniprotkb:Q674X7 intact:EBI-25409992 intact:EBI-949239|uniprotkb:B0QYQ0|uniprotkb:B1AK78|uniprotkb:Q5TGF1|uniprotkb:Q674X6|uniprotkb:Q6ZUD1|uniprotkb:Q8IYN7|uniprotkb:Q8N409|uniprotkb:Q9UIL2|uniprotkb:Q674X4|ensembl:ENSP00000365198|uniprotkb:Q9UPX4|uniprotkb:B1AJZ1 psi-mi:q130171(display_long)|uniprotkb:ARHGAP5(gene name)|psi-mi:ARHGAP5(display_short)|uniprotkb:RHOGAP5(gene name synonym) psi-mi:kazrn_human(display_long)|uniprotkb:KIAA1026(gene name synonym)|uniprotkb:HRIHFB2003(orf name)|uniprotkb:KAZN(gene name)|psi-mi:KAZN(display_short)|uniprotkb:KAZ(gene name synonym)|uniprotkb:C1orf196(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409999|imex:IM-26436-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13017-1(isoform-parent) ensembl:ENSG00000189337(gene)|ensembl:ENST00000376030(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037613|interpro:IPR037614|interpro:IPR037615|interpro:IPR037616|mint:Q674X7|reactome:R-HSA-6809371|refseq:NP_001017999.1|refseq:NP_001018000.1|refseq:NP_001018001.1|refseq:NP_056024.1|refseq:NP_963922.2|refseq:XP_016856260.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CcK8+6n27QR+L45eRsmnJP82TQE9606 rogid:Ai9moSFrBZMcWm4XWkk/vGzD5yE9606 rigid:K+Ax0AmLQM5FseS8owXzhgPg0rA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13017-1 uniprotkb:Q8IZD9 intact:EBI-25409992 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 psi-mi:q130171(display_long)|uniprotkb:ARHGAP5(gene name)|psi-mi:ARHGAP5(display_short)|uniprotkb:RHOGAP5(gene name synonym) psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25409999|imex:IM-26436-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13017-1(isoform-parent) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CcK8+6n27QR+L45eRsmnJP82TQE9606 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rigid:K+Ax0AmLQM5FseS8owXzhgPg0rA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0C2 uniprotkb:Q92619-1 intact:EBI-6149672|ensembl:ENSP00000281154 intact:EBI-25410009 psi-mi:adt4_human(display_long)|uniprotkb:SLC25A31(gene name)|psi-mi:SLC25A31(display_short)|uniprotkb:AAC4(gene name synonym)|uniprotkb:ADP,ATP carrier protein 4(gene name synonym)|uniprotkb:ANT4(gene name synonym)|uniprotkb:Adenine nucleotide translocator 4(gene name synonym)|uniprotkb:SFEC(gene name synonym)|uniprotkb:Solute carrier family 25 member 31(gene name synonym)|uniprotkb:Sperm flagellar energy carrier protein(gene name synonym) psi-mi:q926191(display_long)|uniprotkb:ARHGAP45(gene name)|psi-mi:ARHGAP45(display_short)|uniprotkb:HMHA1(gene name synonym)|uniprotkb:KIAA0223(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410017|imex:IM-26436-214 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001305396.1|refseq:NP_112581.1|ensembl:ENSG00000151475(gene)|ensembl:ENST00000281154(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395 uniprotkb:Q92619-1(isoform-parent) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:41l4B5IjJBVvzEcuNsV2T931oWs9606 rogid:nRGrHrWZk1fyrQODPbmqj6+pJcc9606 rigid:ZtI98dV9w2yf3n15kxDIOGKN9OE false - tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:P35658 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:Q15599 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005|intact:EBI-15579694 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:nhrf2_human(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|ensembl:ENSG00000065054(gene)|ensembl:ENST00000424542(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031197|interpro:IPR036034|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|go:"GO:0042802"(identical protein binding)|dip:DIP-29093N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:P22307 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-1050999|uniprotkb:Q15432|uniprotkb:Q16622|uniprotkb:Q99430|uniprotkb:Q5VVZ1|uniprotkb:D3DQ37|ensembl:ENSP00000360569|uniprotkb:Q6NXF4|uniprotkb:B4DHP6|uniprotkb:A6NM69|uniprotkb:B4DGJ9|uniprotkb:C9JC79|uniprotkb:E1B6W5|uniprotkb:F2Z3J1 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:scp2_human(display_long)|uniprotkb:Propanoyl-CoA C-acyltransferase(gene name synonym)|uniprotkb:Sterol carrier protein X(gene name synonym)|uniprotkb:SCP-chi(gene name synonym)|uniprotkb:SCPX(gene name synonym)|uniprotkb:SCP2(gene name)|psi-mi:SCP2(display_short)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym)|uniprotkb:Non-specific lipid-transfer protein(gene name synonym)|uniprotkb:SCP-2/3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:SCP-2/thiolase(gene name synonym)|uniprotkb:Straight-chain acyl-CoA oxidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_001180528.1|refseq:NP_001007100.1|refseq:NP_001007101.1|refseq:NP_001007251.1|refseq:NP_002970.2|ensembl:ENSG00000116171(gene)|ensembl:ENST00000371514(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032385"(positive regulation of intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0032959"(inositol trisphosphate biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0033814"(propanoyl-CoA C-acyltransferase activity)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045940"(positive regulation of steroid metabolic process)|go:"GO:0050632"(propionyl-CoA C2-trimethyltridecanoyltransferase activity)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|go:"GO:0070538"(oleic acid binding)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1901373"(lipid hydroperoxide transport)|interpro:IPR003033(Sterol-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|interpro:IPR036527|mint:P22307|rcsb pdb:1QND|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-9033241|reactome:R-HSA-9033500|rcsb pdb:2C0L|refseq:XP_016857535.1|refseq:NP_001007099.1|refseq:NP_001180546.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:Vwnu7RuD/2qhcH55Fl9v2TMErtc9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:O95757 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:P51659 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:Q9UBC2 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-2556746|intact:EBI-28972990|ensembl:ENSP00000248070|uniprotkb:B4DKA3|uniprotkb:A2RRF3|uniprotkb:A5PL29 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:ep15r_human(display_long)|uniprotkb:EPS15R(gene name synonym)|uniprotkb:Eps15-related protein(gene name synonym)|uniprotkb:EPS15L1(gene name)|psi-mi:EPS15L1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_067058.1|ensembl:ENSP00000248070|ensembl:ENST00000455140|ensembl:ENSP00000393313|ensembl:ENST00000535753|ensembl:ENSP00000440103|ensembl:ENST00000597937|ensembl:ENSP00000472267|ensembl:ENST00000602022|ensembl:ENSP00000471981|ensembl:ENSG00000127527(gene)|ensembl:ENST00000248070(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0045296"(cadherin binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBC2|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0030132"(clathrin coat of coated pit)|refseq:NP_001245303.1|refseq:NP_001245304.1|refseq:NP_001245305.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:6Bsao5czetxRxIiy3O/rZox4U+Y9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:P42566 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:Q13011 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-711968|ensembl:ENSP00000221418|ensembl:ENSP00000489530|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|uniprotkb:A8K745 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 ensembl:ENSG00000104823(gene)|ensembl:ENSG00000282853(gene)|ensembl:ENST00000221418(transcript)|ensembl:ENST00000634245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016020"(membrane)|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:Q13011|rcsb pdb:2VRE|reactome:R-HSA-9033241|refseq:NP_001389.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:P09496 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-1171169|uniprotkb:Q2XPN5|uniprotkb:Q53XZ1|uniprotkb:A8K4W3|uniprotkb:B4DIN1|uniprotkb:F5H6N3|ensembl:ENSP00000242285|ensembl:ENSP00000401019 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:clca_human(display_long)|uniprotkb:CLTA(gene name)|psi-mi:CLTA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_001070145.1|refseq:NP_001824.1|refseq:NP_009027.1|refseq:NP_001171689.1|refseq:NP_001171691.1|ensembl:ENSG00000122705(gene)|ensembl:ENST00000242285(transcript)|ensembl:ENST00000433436(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P09496|rcsb pdb:6E5N|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-3928665 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:RCF3QpQKI1yZFOTAyzhvRkR9ek49606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:Q969X6 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:P04040 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_001743.1|ensembl:ENSG00000121691(gene)|ensembl:ENST00000241052(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:Q96CW1 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-297683|ensembl:ENSP00000292807|uniprotkb:A6NE12|uniprotkb:P20172|uniprotkb:P53679|uniprotkb:D3DNT1 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:ap2m1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:AP2M1(gene name)|psi-mi:AP2M1(display_short)|uniprotkb:CLAPM1(gene name synonym)|uniprotkb:KIAA0109(gene name synonym)|uniprotkb:Adaptin-mu2(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:HA2 50 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 ensembl:ENSG00000161203(gene)|ensembl:ENST00000292807(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0034622"|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0031623"(receptor internalization)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:Q96CW1|rcsb pdb:1H6E|rcsb pdb:6BNT|rcsb pdb:6URI|reactome:R-HSA-164939|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|reactome:R-HSA-182218|refseq:NP_001020376.1|refseq:NP_004059.2|refseq:NP_001298127.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:O94973 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENST00000448903(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O94973|reactome:R-HSA-167590|ensembl:ENSG00000183020(gene)|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15811 uniprotkb:O95782 intact:EBI-602041|uniprotkb:B4DTM2|uniprotkb:O95216|uniprotkb:Q9UET5|uniprotkb:Q9UK60|uniprotkb:Q9UNK1|uniprotkb:Q9UNK2|uniprotkb:Q9UQ92|uniprotkb:Q1ED40|uniprotkb:Q0PW97|uniprotkb:E7ERJ1|uniprotkb:Q14BD3|uniprotkb:Q20BK3|intact:EBI-11029034|uniprotkb:A7Y322|uniprotkb:A8CTX8|uniprotkb:A8CTY3|uniprotkb:A8CTY7|uniprotkb:A8D7D0|uniprotkb:A8DCP3|uniprotkb:E9PE44|uniprotkb:E9PG01|uniprotkb:E9PHV2|uniprotkb:Q0PW94|uniprotkb:Q0PW95|intact:EBI-28971797|ensembl:ENSP00000370719 intact:EBI-353552|uniprotkb:Q96CI7|uniprotkb:Q96PP6|uniprotkb:Q96PP7|uniprotkb:Q9H070|intact:EBI-28973302|ensembl:ENSP00000351926 psi-mi:itsn1_human(display_long)|uniprotkb:SH3 domain-containing protein 1A(gene name synonym)|uniprotkb:SH3P17(gene name synonym)|uniprotkb:ITSN1(gene name)|psi-mi:ITSN1(display_short)|uniprotkb:ITSN(gene name synonym)|uniprotkb:SH3D1A(gene name synonym) psi-mi:ap2a1_human(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410025|imex:IM-26436-126 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000381291|ensembl:ENSP00000370691|ensembl:ENSP00000370719|ensembl:ENST00000399338|ensembl:ENSP00000382275|ensembl:ENST00000399349|ensembl:ENSP00000382286|ensembl:ENSP00000382289|ensembl:ENST00000399353|ensembl:ENSP00000382290|ensembl:ENST00000399367|ensembl:ENSP00000382301|ensembl:ENST00000399352|refseq:NP_001001132.1|refseq:NP_003015.2|refseq:XP_011527994.1|refseq:XP_011527995.1|refseq:NP_001317938.1|refseq:NP_001317939.1|refseq:NP_001317940.1|refseq:NP_001317941.1|refseq:XP_016883917.1|refseq:XP_016883921.1|refseq:XP_016883922.1|refseq:XP_016883929.1|dip:DIP-33609N|ensembl:ENSG00000205726(gene)|ensembl:ENST00000381318(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q15811|rcsb pdb:1KI1|rcsb pdb:2KGR|rcsb pdb:2KHN|rcsb pdb:3FIA|rcsb pdb:3QBV|rcsb pdb:4IIM|rcsb pdb:5HZI|rcsb pdb:5HZJ|rcsb pdb:5HZK|rcsb pdb:6GBU|rcsb pdb:6H5T|reactome:R-HSA-193648|reactome:R-HSA-3928662|reactome:R-HSA-416482|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013408 refseq:NP_055018.2|refseq:NP_570603.2|ensembl:ENST00000354293|ensembl:ENSP00000346246|ensembl:ENSP00000351926|ensembl:ENSG00000196961(gene)|ensembl:ENST00000359032(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O95782|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|dip:DIP-33164N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gYC3xiyk4dbnCXhZ8Rzn3rzafyU9606 rogid:egkaIAhvIi1FqNr+8KEFeJaYZcc9606 rigid:g0cxWOmfOZyz3y5QT/vkSMQS2No false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:P17026 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-20803387|ensembl:ENSP00000298299|uniprotkb:Q5T741|uniprotkb:Q96FM4 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:znf22_human(display_long)|uniprotkb:ZNF22(gene name)|psi-mi:ZNF22(display_short)|uniprotkb:KOX15(gene name synonym)|uniprotkb:KROX26(gene name synonym)|uniprotkb:Zinc finger protein KOX15(gene name synonym)|uniprotkb:Zinc finger protein Krox-26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 go:"GO:0042476"(odontogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P17026|ensembl:ENSG00000165512(gene)|ensembl:ENST00000298299(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|refseq:NP_008894.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:oWVXwJp7odj/wOKyq0j+76pJFoo9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q9NNW5 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q9NXA8 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-6556144|uniprotkb:B4DFM4|uniprotkb:B4DYJ5|uniprotkb:F5H5Z9|uniprotkb:Q5T294|uniprotkb:Q5T295|uniprotkb:Q9Y6E6|ensembl:ENSP00000380509|ensembl:ENSP00000476228|ensembl:ENSP00000505086|ensembl:ENSP00000505496 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:sir5_human(display_long)|uniprotkb:SIRT5(gene name)|psi-mi:SIRT5(display_short)|uniprotkb:SIR2L5(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 5(gene name synonym)|uniprotkb:SIR2-like protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_001180196.1|refseq:NP_001229756.1|refseq:NP_036373.1|refseq:NP_112534.1|refseq:XP_005249025.1|ensembl:ENSG00000124523(gene)|ensembl:ENST00000397350(transcript)|ensembl:ENST00000606117(transcript)|ensembl:ENST00000680151(transcript)|ensembl:ENST00000680432(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010566"(regulation of ketone biosynthetic process)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0036046"(protein demalonylation)|go:"GO:0036047"(peptidyl-lysine demalonylation)|go:"GO:0036048"(protein desuccinylation)|go:"GO:0036049"(peptidyl-lysine desuccinylation)|go:"GO:0036054"(protein-malonyllysine demalonylase activity)|go:"GO:0036055"(protein-succinyllysine desuccinylase activity)|go:"GO:0061697"(protein-glutaryllysine deglutarylase activity)|go:"GO:0061698"(protein deglutarylation)|go:"GO:0070403"(NAD+ binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR027546|interpro:IPR029035|rcsb pdb:2B4Y|rcsb pdb:2NYR|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4G1C|rcsb pdb:4HDA|rcsb pdb:5BWL|rcsb pdb:5XHS|rcsb pdb:6ACE|rcsb pdb:6ACL|rcsb pdb:6ACO|rcsb pdb:6ACP|rcsb pdb:6EQS|rcsb pdb:6LJK|rcsb pdb:6LJM|rcsb pdb:6LJN|reactome:R-HSA-2151201 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:w8a5w8pZghQpNpbgYCsuPIj+Sgo9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q15050 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-749186|uniprotkb:Q9BUX8|ensembl:ENSP00000322396 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:rrs1_human(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:KIAA0112(gene name synonym)|uniprotkb:RRR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_055984.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|mint:Q15050|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000179041(gene)|ensembl:ENST00000320270(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:0Nm9UoIGLBiqOGl0E2BA0S5EXIU9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q15291 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:P27986 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q9Y2I1 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-2688731|uniprotkb:Q6PIB4|uniprotkb:Q9UEU4|uniprotkb:Q7L8M3|uniprotkb:Q6PGP3|uniprotkb:Q9UFW3|uniprotkb:Q7Z2X6|uniprotkb:Q9UES6|uniprotkb:C9J245|ensembl:ENSP00000339958|ensembl:ENSP00000418232 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:nisch_human(display_long)|uniprotkb:IRAS(gene name synonym)|uniprotkb:KIAA0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor antisera-selected protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym)|uniprotkb:Imidazoline-1 receptor candidate protein(gene name synonym)|uniprotkb:NISCH(gene name)|psi-mi:NISCH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_009115.2|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q9Y2I1|rcsb pdb:3P0C|reactome:R-HSA-9013149|reactome:R-HSA-9696264|reactome:R-HSA-9696270|ensembl:ENSG00000010322(gene)|ensembl:ENST00000345716(transcript)|ensembl:ENST00000479054(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|refseq:NP_001263222.1|refseq:NP_001263223.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:GuBgG6MUrD5p1hIhGGmrtCjT0jQ9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q03164 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q14739 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q96AE4 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-711404|uniprotkb:Q12828|ensembl:ENSP00000359804 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:fubp1_human(display_long)|uniprotkb:FUBP1(gene name)|psi-mi:FUBP1(display_short)|uniprotkb:DNA helicase V(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q96AE4|rcsb pdb:1J4W|rcsb pdb:2KXH|rcsb pdb:4LIJ|rcsb pdb:6Y24|rcsb pdb:6Y2C|rcsb pdb:6Y2D|ensembl:ENSG00000162613(gene)|ensembl:ENST00000370768(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|refseq:NP_003893.2|refseq:NP_001290362.1|refseq:XP_016858232.1|dip:DIP-47273N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:38IaQgYv8qLMAryXO0lbfzgjjsM9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q00688 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-1044081|uniprotkb:Q14317|ensembl:ENSP00000216330|ensembl:ENSP00000379374|uniprotkb:B2R4Q9 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:fkbp3_human(display_long)|uniprotkb:FKBP3(gene name)|psi-mi:FKBP3(display_short)|uniprotkb:FKBP25(gene name synonym)|uniprotkb:FK506-binding protein 3(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP25(gene name synonym)|uniprotkb:Rapamycin-selective 25 kDa immunophilin(gene name synonym)|uniprotkb:25 kDa FK506-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_002004.1|ensembl:ENSG00000100442(gene)|ensembl:ENST00000216330(transcript)|ensembl:ENST00000396062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR041200|interpro:IPR043368|mint:Q00688|rcsb pdb:1PBK|rcsb pdb:2KFV|rcsb pdb:2MPH|rcsb pdb:5D75|rcsb pdb:5GPG|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:xU5FDlTZzy8veAtOaoLtQMeBsr09606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:O43854 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-2557492|uniprotkb:O43855|uniprotkb:Q5D094|uniprotkb:B2R763|uniprotkb:Q8N610|ensembl:ENSP00000296591 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:edil3_human(display_long)|uniprotkb:EDIL3(gene name)|psi-mi:EDIL3(display_short)|uniprotkb:DEL1(gene name synonym)|uniprotkb:Developmentally-regulated endothelial cell locus 1 protein(gene name synonym)|uniprotkb:Integrin-binding protein DEL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_005702.3|refseq:NP_001265571.1|ensembl:ENSG00000164176(gene)|ensembl:ENST00000296591(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007155"(cell adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|rcsb pdb:4D90 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:vE+497pBdweD9fCx+2XqmYeFmC49606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:P55201 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q9UBL3 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:Q9BZZ5 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-1048422|uniprotkb:O15441|uniprotkb:Q9Y4J7|uniprotkb:D3DR21|uniprotkb:B4DRJ2|uniprotkb:B4E283|uniprotkb:B4DGR0|ensembl:ENSP00000431391 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:api5_human(display_long)|uniprotkb:Fibroblast growth factor 2-interacting factor(gene name synonym)|uniprotkb:Protein XAGL(gene name synonym)|uniprotkb:Antiapoptosis clone 11 protein(gene name synonym)|uniprotkb:Cell migration-inducing gene 8 protein(gene name synonym)|uniprotkb:API5(gene name)|psi-mi:API5(display_short)|uniprotkb:MIG8(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_001136402.1|refseq:NP_001136403.1|refseq:NP_006586.1|refseq:NP_001230676.1|ensembl:ENSG00000166181(gene)|ensembl:ENST00000531273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR008383(Apoptosis inhibitory 5)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BZZ5|rcsb pdb:3U0R|rcsb pdb:3V6A|rcsb pdb:6L4O - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:WYNbM5GNolgFNszccnMEanszDgU9606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O08908 uniprotkb:P39687 intact:EBI-643570|ensembl:ENSMUSP00000034296|uniprotkb:Q5U3K7 intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864 psi-mi:p85b_mouse(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym)|uniprotkb:Pik3r2(gene name)|psi-mi:Pik3r2(display_short) psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410059|imex:IM-26436-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031834(gene)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|ensembl:ENSMUST00000034296(transcript)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0030971"(receptor tyrosine kinase binding)|refseq:NP_032867.2|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|rcsb pdb:2Y3A|reactome:R-MMU-109704|reactome:R-MMU-112399|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1266695|reactome:R-MMU-1433557|reactome:R-MMU-1660499|reactome:R-MMU-186763|reactome:R-MMU-198203|reactome:R-MMU-202424|reactome:R-MMU-2029485|reactome:R-MMU-210993|reactome:R-MMU-2424491|reactome:R-MMU-2730905|reactome:R-MMU-388841|reactome:R-MMU-389357|reactome:R-MMU-416476|reactome:R-MMU-4420097|reactome:R-MMU-6811558|reactome:R-MMU-512988|reactome:R-MMU-8853659|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013409|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9696264|reactome:R-MMU-5673001|reactome:R-MMU-9696270|reactome:R-MMU-9696273 refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8SNYg9Yr1SPNGhxsho1rANQT/Ks10090 rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606 rigid:ymgY5lfeJupkwPDsbIgN3pmKlsU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UIL1 uniprotkb:Q91Z67 intact:EBI-2686537|uniprotkb:Q7L2Y0|uniprotkb:Q9BZB2|uniprotkb:Q96JY9|uniprotkb:Q7Z4P2|uniprotkb:B7WPH7|uniprotkb:Q6P5T9|intact:EBI-2812448|uniprotkb:D3DNY7|uniprotkb:E9PB65 intact:EBI-16730393|ensembl:ENSMUSP00000095195|uniprotkb:B2RY13|uniprotkb:Q3V1V8|uniprotkb:Q61054 psi-mi:scoc_human(display_long)|uniprotkb:SCOCO(gene name synonym)|uniprotkb:HRIHFB2072(orf name)|uniprotkb:SCOC(gene name)|psi-mi:SCOC(display_short) psi-mi:srgp2_mouse(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:Formin-binding protein 27(gene name synonym)|uniprotkb:Srgap2(gene name)|psi-mi:Srgap2(display_short)|uniprotkb:Fbp27(gene name synonym)|uniprotkb:Fnbp2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410158|imex:IM-26436-218 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001146918.1|refseq:NP_001146956.1|refseq:NP_001147024.1|refseq:NP_001147057.1|refseq:NP_001147107.1|refseq:NP_001147135.1|refseq:NP_001147162.1|refseq:NP_115936.2|interpro:IPR019357|reactome:R-HSA-6811440|rcsb pdb:4BWD|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0000139"(Golgi membrane) ensembl:ENSMUSG00000026425(gene)|ensembl:ENSMUST00000097588(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:Q91Z67|reactome:R-MMU-5663220|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|refseq:NP_001074480.2|refseq:XP_006529197.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:l1hHXnWtTNJbZZBNyDtExzt5SSQ9606 rogid:MLCAa8wEQvKNPatehgSzcizs2YI10090 rigid:zdzih6CICSqsyh0MJNUMeCme/EE false - tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q96P70 intact:EBI-25410117 intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:O95881 intact:EBI-25410117 intact:EBI-2564581|uniprotkb:B3KQS0|uniprotkb:Q5T1T4|uniprotkb:Q96H50|ensembl:ENSP00000360688 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:txd12_human(display_long)|uniprotkb:TXNDC12(gene name)|psi-mi:TXNDC12(display_short)|uniprotkb:TLP19(gene name synonym)|uniprotkb:Thioredoxin-like protein p19(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 19(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 18(gene name synonym)|uniprotkb:hTLP19(gene name synonym)|uniprotkb:UNQ713/PRO1376(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_056997.1|ensembl:ENSG00000117862(gene)|ensembl:ENST00000371626(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0019153"("protein-disulfide reductase (glutathione) activity")|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037462|rcsb pdb:1SEN|rcsb pdb:2K8V - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:lgsrfn2RsfqJlKY0WWgUnvmMImM9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q13243 intact:EBI-25410117 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q9BWJ5 intact:EBI-25410117 intact:EBI-2555428|uniprotkb:Q7RTV1|uniprotkb:B2R568|ensembl:ENSP00000356541 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:sf3b5_human(display_long)|uniprotkb:SF3B10(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:SF3B5(gene name)|psi-mi:SF3B5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_112577.1|ensembl:ENSG00000169976(gene)|ensembl:ENST00000367569(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q9BWJ5|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5Z57 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:wuQBsSytGhSg64IQSmEJXe+26zQ9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:O00232 intact:EBI-25410117 intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q92621 intact:EBI-25410117 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q92665 intact:EBI-25410117 intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q9BYN8 intact:EBI-25410117 intact:EBI-721378|uniprotkb:Q96Q58|ensembl:ENSP00000369682 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:rt26_human(display_long)|uniprotkb:28S ribosomal protein S13, mitochondrial(gene name synonym)|uniprotkb:MRPS26(gene name)|psi-mi:MRPS26(display_short)|uniprotkb:RPMS13(gene name synonym)|uniprotkb:C20orf193(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_110438.1|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125901(gene)|ensembl:ENST00000380325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR026140|mint:Q9BYN8 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:ZygMazfhjHbx+aFhRkeG87c4L6E9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:O60783 intact:EBI-25410117 intact:EBI-1045956|uniprotkb:Q5R358|ensembl:ENSP00000420714 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:rt14_human(display_long)|uniprotkb:MRPS14(gene name)|psi-mi:MRPS14(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS14m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_071383.1|ensembl:ENSG00000120333(gene)|ensembl:ENST00000476371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001209(Ribosomal protein S14)|mint:O60783|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|go:"GO:0005739"(mitochondrion)|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:IW06v3pp8xJJXxPcizKjsNIZi/I9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q8IWI9 intact:EBI-25410117 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:P61244 intact:EBI-25410117 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q5RKV6 intact:EBI-25410117 intact:EBI-2841747|ensembl:ENSP00000398597 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q9C005 intact:EBI-25410117 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86YR7-3 uniprotkb:Q9P2R3 intact:EBI-25410117 intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187 psi-mi:q86yr73(display_long)|uniprotkb:MCF2L2(gene name)|psi-mi:MCF2L2(display_short)|uniprotkb:DRG(gene name synonym)|uniprotkb:KIAA0861(gene name synonym) psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410124|imex:IM-26436-128 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86YR7-3(isoform-parent) refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qUcovUDk6R8eYIe2GzLD0A5xeVY9606 rogid:237ungtRc80jqTOKBUnFX9qDUGw9606 rigid:6F3xOBmkYjlRxuTGu5h/hErVeag false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96N67-2 uniprotkb:P12277 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410097|imex:IM-26436-216 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:5cs6hSSKkTPlmt6eqaIKMXMDUEs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96N67-2 uniprotkb:P22314 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410097|imex:IM-26436-216 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168 - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606 rigid:5cs6hSSKkTPlmt6eqaIKMXMDUEs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96N67-2 uniprotkb:Q16576 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410097|imex:IM-26436-216 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:5cs6hSSKkTPlmt6eqaIKMXMDUEs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96N67-2 uniprotkb:P14314 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-716953|uniprotkb:Q96BU9|uniprotkb:Q96D06|uniprotkb:Q9P0W9|uniprotkb:A8K318|ensembl:ENSP00000465461 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:glu2b_human(display_long)|uniprotkb:Glucosidase II subunit beta(gene name synonym)|uniprotkb:Protein kinase C substrate 60.1 kDa protein heavy chain(gene name synonym)|uniprotkb:80K-H protein(gene name synonym)|uniprotkb:PRKCSH(gene name)|psi-mi:PRKCSH(display_short)|uniprotkb:G19P1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410097|imex:IM-26436-216 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:NP_001001329.1|refseq:NP_002734.2|refseq:XP_011526433.1|refseq:XP_011526434.1|refseq:NP_001276031.1|ensembl:ENSG00000130175(gene)|ensembl:ENST00000589838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006491"(N-glycan processing)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028146|interpro:IPR036055|interpro:IPR036607|interpro:IPR039794|interpro:IPR044865|mint:P14314|reactome:R-HSA-381426|reactome:R-HSA-532668|reactome:R-HSA-879415|reactome:R-HSA-8957275|reactome:R-HSA-901042|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016882466.1 - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:hs2AZthZKK6KVW8Blm1RuZVh1QM9606 rigid:5cs6hSSKkTPlmt6eqaIKMXMDUEs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96N67-2 uniprotkb:P13667 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410097|imex:IM-26436-216 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:5cs6hSSKkTPlmt6eqaIKMXMDUEs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96N67-2 uniprotkb:Q7Z6I6 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-2814810|uniprotkb:Q5SY52|uniprotkb:Q6ZML6|uniprotkb:Q5SY53|uniprotkb:Q7Z3J8|uniprotkb:Q86XI7|uniprotkb:Q5SY54|ensembl:ENSP00000356992 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:rhg30_human(display_long)|uniprotkb:ARHGAP30(gene name)|psi-mi:ARHGAP30(display_short)|uniprotkb:Rho-type GTPase-activating protein 30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410097|imex:IM-26436-216 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:XP_011507693.1|refseq:NP_001020769.1|refseq:NP_859071.2|refseq:NP_001274529.1|refseq:NP_001274531.1|ensembl:ENSG00000186517(gene)|ensembl:ENST00000368013(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420|go:"GO:0005829"(cytosol)|refseq:XP_005245130.1 - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:L0Pbx3s9V/lw/NAiHZHnvXwI8Hw9606 rigid:5cs6hSSKkTPlmt6eqaIKMXMDUEs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96N67-2 uniprotkb:Q9BZZ5 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-1048422|uniprotkb:O15441|uniprotkb:Q9Y4J7|uniprotkb:D3DR21|uniprotkb:B4DRJ2|uniprotkb:B4E283|uniprotkb:B4DGR0|ensembl:ENSP00000431391 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:api5_human(display_long)|uniprotkb:Fibroblast growth factor 2-interacting factor(gene name synonym)|uniprotkb:Protein XAGL(gene name synonym)|uniprotkb:Antiapoptosis clone 11 protein(gene name synonym)|uniprotkb:Cell migration-inducing gene 8 protein(gene name synonym)|uniprotkb:API5(gene name)|psi-mi:API5(display_short)|uniprotkb:MIG8(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410097|imex:IM-26436-216 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:NP_001136402.1|refseq:NP_001136403.1|refseq:NP_006586.1|refseq:NP_001230676.1|ensembl:ENSG00000166181(gene)|ensembl:ENST00000531273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR008383(Apoptosis inhibitory 5)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BZZ5|rcsb pdb:3U0R|rcsb pdb:3V6A|rcsb pdb:6L4O - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:WYNbM5GNolgFNszccnMEanszDgU9606 rigid:5cs6hSSKkTPlmt6eqaIKMXMDUEs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:P06753 intact:EBI-25410166 intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:P06396 intact:EBI-25410166 intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:Q6UN15 intact:EBI-25410166 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:P26368 intact:EBI-25410166 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:P55854 intact:EBI-25410166 intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:P30153 intact:EBI-25410166 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:Q96SB3 intact:EBI-25410166 intact:EBI-351275|uniprotkb:Q8TCR9|intact:EBI-28984643|ensembl:ENSP00000478767|intact:EBI-4401886|uniprotkb:D3DTX6 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:neb2_human(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:PPP1R9B(gene name)|psi-mi:PPP1R9B(display_short)|uniprotkb:PPP1R6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) ensembl:ENSG00000108819(gene)|ensembl:ENST00000612501(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035094"(response to nicotine)|go:"GO:0035690"|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060179"(male mating behavior)|go:"GO:0061458"(reproductive system development)|go:"GO:0071315"(cellular response to morphine)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097338"(response to clozapine)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903119"(protein localization to actin cytoskeleton)|go:"GO:1904372"(positive regulation of protein localization to actin cortical patch)|go:"GO:1904373"(response to kainic acid)|go:"GO:1904386"(response to L-phenylalanine derivative)|go:"GO:1990778"(protein localization to cell periphery)|go:"GO:1990780"(cytoplasmic side of dendritic spine plasma membrane)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029921|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q96SB3|ensembl:ENSP00000478767|refseq:NP_115984.3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:X6fQLpaYhXCqzRlQNEoX67P/HbU9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:O14974 intact:EBI-25410166 intact:EBI-351726|uniprotkb:Q2NKL4|uniprotkb:Q569H0|uniprotkb:Q86WU3|uniprotkb:Q8NFR6|uniprotkb:Q9BYH0|intact:EBI-28988491|uniprotkb:B4DZ09|uniprotkb:F8VWB4|ensembl:ENSP00000261207|ensembl:ENSP00000389168 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:mypt1_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short)|uniprotkb:MBS(gene name synonym)|uniprotkb:MYPT1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_001137357.1|refseq:NP_001137358.1|refseq:NP_002471.1|refseq:NP_001231919.1|refseq:NP_001231921.1|refseq:XP_011536685.1|ensembl:ENSP00000261207|ensembl:ENST00000437004|ensembl:ENSP00000416769|ensembl:ENSP00000389168|ensembl:ENSP00000449514|ensembl:ENST00000550107|ensembl:ENSP00000446855|ensembl:ENST00000546369|dip:DIP-33186N|ensembl:ENSG00000058272(gene)|ensembl:ENST00000261207(transcript)|ensembl:ENST00000450142(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770|mint:O14974|rcsb pdb:2KJY|rcsb pdb:5HUZ|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:Xi5lGskc0tWQCHtbYlgR45ERMSk9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:P30876 intact:EBI-25410166 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:A1L390 intact:EBI-25410166 intact:EBI-4401429|ensembl:ENSP00000247226|uniprotkb:A1L389|uniprotkb:B5MEC9|uniprotkb:O60339|uniprotkb:Q6GMS3|uniprotkb:Q6P4B1|uniprotkb:Q7L3S3|uniprotkb:Q86SW7|uniprotkb:Q8TEF5|uniprotkb:Q96EW6|uniprotkb:Q9BT82|intact:EBI-28970790 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:pkhg3_human(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) ensembl:ENSG00000126822(gene)|ensembl:ENST00000247226(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR043324|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013408|ensembl:ENSP00000247226|ensembl:ENST00000394691|ensembl:ENSP00000378183|refseq:XP_016876646.1|refseq:NP_001295076.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:+obep09w4klmkB8i13aA5FQW2609606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:Q15149 intact:EBI-25410166 intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:Q9Y2D5 intact:EBI-25410166 intact:EBI-1754555|uniprotkb:Q9UG26|uniprotkb:B1ALX9|uniprotkb:B2RTU4|uniprotkb:B3KQ00|uniprotkb:B4DTZ2|uniprotkb:B7ZW07|uniprotkb:B9EJB5 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:akap2_human(display_long)|uniprotkb:AKAP2(gene name)|psi-mi:AKAP2(display_short)|uniprotkb:KIAA0920(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP-KL(gene name synonym)|uniprotkb:PRKA2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_001004065.2|refseq:NP_001130034.1|refseq:NP_001185585.1|refseq:NP_009134.1|refseq:NP_671492.1|interpro:IPR029304 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:xfHb6tD0ToXJPHpl4MlbKczjzSg9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:O43809 intact:EBI-25410166 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:Q6WCQ1 intact:EBI-25410166 intact:EBI-1022605|uniprotkb:Q3KQZ5|uniprotkb:Q5FB94|uniprotkb:Q6DHW2|uniprotkb:Q7Z5Y2|uniprotkb:Q8N390|uniprotkb:Q96G40|ensembl:ENSP00000342379 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:mprip_human(display_long)|uniprotkb:MRIP(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym)|uniprotkb:MPRIP(gene name)|psi-mi:MPRIP(display_short)|uniprotkb:KIAA0864(gene name synonym)|uniprotkb:RHOIP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) ensembl:ENSG00000133030(gene)|ensembl:ENST00000341712(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q6WCQ1|reactome:R-HSA-6802952|refseq:NP_055949.2|refseq:NP_958431.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:QoGbbg2ehuQogDM1Dlxzw6xj59s9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:P30533 intact:EBI-25410166 intact:EBI-715927|uniprotkb:Q2M310|uniprotkb:Q53HQ3|uniprotkb:Q53HS6|uniprotkb:D3DVR9|ensembl:ENSP00000497444 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:amrp_human(display_long)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:LRPAP1(gene name)|psi-mi:LRPAP1(display_short)|uniprotkb:A2MRAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_002328.1|ensembl:ENSG00000163956(gene)|ensembl:ENST00000650182(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900116"(extracellular negative regulation of signal transduction)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:P30533|rcsb pdb:1LRE|rcsb pdb:1NRE|rcsb pdb:1OP1|rcsb pdb:1OV2|rcsb pdb:2FCW|rcsb pdb:2FTU|rcsb pdb:2FYL|rcsb pdb:2P01|rcsb pdb:2P03|dip:DIP-39355N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:TIbL+P1GW4op4Qawa4lpg8iXUaQ9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:P52292 intact:EBI-25410166 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:Q9BY89 intact:EBI-25410166 intact:EBI-8796741|intact:EBI-28980779|ensembl:ENSP00000351207|ensembl:ENSP00000385152|uniprotkb:B7ZW08|uniprotkb:Q5THZ5|uniprotkb:B0QYF2 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:k1671_human(display_long)|uniprotkb:KIAA1671(gene name)|psi-mi:KIAA1671(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) ensembl:ENSG00000197077(gene)|ensembl:ENST00000358431(transcript)|ensembl:ENST00000406486(transcript)|interpro:IPR032764|interpro:IPR040006|ensembl:ENSP00000351207|ensembl:ENST00000401395|ensembl:ENSP00000385377|ensembl:ENSP00000385152|refseq:XP_005261850.1|refseq:XP_005261851.1|refseq:NP_001138678.1|refseq:XP_006724409.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:7mCSVXo/8Z2MUHqsxKKXrBvOe749606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:Q9HD26 intact:EBI-25410166 intact:EBI-349832|uniprotkb:A6NM30|uniprotkb:Q59FS4|uniprotkb:Q969U8|ensembl:ENSP00000357484 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:gopc_human(display_long)|uniprotkb:CAL(gene name synonym)|uniprotkb:FIG(gene name synonym)|uniprotkb:GOPC(gene name)|psi-mi:GOPC(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym)|uniprotkb:CFTR-associated ligand(gene name synonym)|uniprotkb:Fused in glioblastoma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_001017408.1|refseq:NP_065132.1|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045176"(apical protein localization)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR038879|mint:Q9HD26|rcsb pdb:2DC2|rcsb pdb:2LOB|rcsb pdb:4E34|rcsb pdb:4E35|rcsb pdb:4JOE|rcsb pdb:4JOF|rcsb pdb:4JOG|rcsb pdb:4JOH|rcsb pdb:4JOJ|rcsb pdb:4JOK|rcsb pdb:4JOP|rcsb pdb:4JOR|rcsb pdb:4K6Y|rcsb pdb:4K72|rcsb pdb:4K75|rcsb pdb:4K76|rcsb pdb:4K78|rcsb pdb:4NMO|rcsb pdb:4NMP|rcsb pdb:4NMQ|rcsb pdb:4NMR|rcsb pdb:4NMS|rcsb pdb:4NMT|go:"GO:0042802"(identical protein binding)|rcsb pdb:4NMV|rcsb pdb:4Q6H|rcsb pdb:4Q6S|rcsb pdb:5IC3|rcsb pdb:5K4F|rcsb pdb:6OV7|rcsb pdb:6V84|rcsb pdb:6XNJ|reactome:R-HSA-5627083|reactome:R-HSA-9013406|ensembl:ENSG00000047932(gene)|ensembl:ENST00000368498(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032991"(protein-containing complex) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:bXzu5wvJifZwB+Q52cgC4tZQl/k9606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VT97-1 uniprotkb:O00213 intact:EBI-25410166 intact:EBI-81694|uniprotkb:Q96A93|uniprotkb:A6NH82|uniprotkb:A6NL69|ensembl:ENSP00000477213|uniprotkb:D3DQT2|uniprotkb:B7Z2Y0|uniprotkb:A1E379|uniprotkb:B7Z1J5|uniprotkb:B7Z1J6|uniprotkb:Q7Z324|uniprotkb:V9GYK0|uniprotkb:V9GYT4 psi-mi:q5vt971(display_long)|uniprotkb:SYDE2(gene name)|psi-mi:SYDE2(display_short) psi-mi:apbb1_human(display_long)|uniprotkb:APBB1(gene name)|psi-mi:APBB1(display_short)|uniprotkb:FE65(gene name synonym)|uniprotkb:RIR(gene name synonym)|uniprotkb:Protein Fe65(gene name synonym)|uniprotkb:Amyloid-beta A4 precursor protein-binding family B member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410172|imex:IM-26436-258 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q5VT97-1(isoform-parent) refseq:NP_001244254.1|refseq:XP_016873130.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0010039"(response to iron ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042734"(presynaptic membrane)|ensembl:ENSG00000166313(gene)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|ensembl:ENST00000609360(transcript)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044304"(main axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|go:"GO:1990761"(growth cone lamellipodium)|go:"GO:1990812"(growth cone filopodium)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR039576|mint:O00213|rcsb pdb:2E45|rcsb pdb:2HO2|rcsb pdb:2IDH|rcsb pdb:2OEI|rcsb pdb:3D8D|rcsb pdb:3D8E|rcsb pdb:3D8F|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:5NQH|reactome:R-HSA-5693565|rcsb pdb:3DXC|refseq:XP_011518342.1|refseq:NP_001244248.1|refseq:NP_001155.1|refseq:NP_663722.1|refseq:NP_001244252.1|refseq:NP_001244255.1|refseq:NP_001244249.1|refseq:NP_001244250.1|dip:DIP-30903N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:MDrCSa6NwRdAQneT1NzxWPrbKQQ9606 rogid:3vC/0PYrQRCoZLpyDN1xhXmVsD89606 rigid:OOyGMyKh0tKmJPWTpGVcdq8atKE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:P56270 intact:EBI-25410216 intact:EBI-1809742|uniprotkb:A8QJL9|uniprotkb:Q15703|uniprotkb:Q99443|uniprotkb:H3BQD6|uniprotkb:G5E927|uniprotkb:Q8NFN7|uniprotkb:C6G496|ensembl:ENSP00000313362 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:maz_human(display_long)|uniprotkb:Transcription factor Zif87(gene name synonym)|uniprotkb:Zinc finger protein 801(gene name synonym)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)|uniprotkb:Purine-binding transcription factor(gene name synonym)|uniprotkb:Pur-1(gene name synonym)|uniprotkb:ZF87(gene name synonym)|uniprotkb:ZNF801(gene name synonym)|uniprotkb:Serum amyloid A-activating factor-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_002374.2|refseq:NP_001036004.1|refseq:NP_001263205.1|refseq:NP_001263204.1|ensembl:ENSG00000103495(gene)|ensembl:ENST00000322945(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P56270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:zuCDXhF2wr8gmTyjBNse9kVUqSw9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:P82970 intact:EBI-25410216 intact:EBI-3951862|uniprotkb:Q5JSL1|ensembl:ENSP00000350848 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:hmgn5_human(display_long)|uniprotkb:HMGN5(gene name)|psi-mi:HMGN5(display_short)|uniprotkb:NSBP1(gene name synonym)|uniprotkb:Nucleosome-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_110390.1|ensembl:ENSG00000198157(gene)|ensembl:ENST00000358130(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|interpro:IPR040164 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:B+ej0KzpeCvCXlJc+6DemTmLGB89606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:P43694 intact:EBI-25410216 intact:EBI-7049352|uniprotkb:B7ZKZ4|ensembl:ENSP00000334458|ensembl:ENSP00000482268|ensembl:ENSP00000495511|uniprotkb:Q5IFM8|intact:MINT-3379484|uniprotkb:Q3MJ45|uniprotkb:B7ZKX0 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:gata4_human(display_long)|uniprotkb:GATA4(gene name)|psi-mi:GATA4(display_short)|uniprotkb:GATA-binding factor 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001295022.1|refseq:XP_011542119.1|refseq:XP_011542120.1|ensembl:ENSG00000136574(gene)|ensembl:ENSG00000285109(gene)|ensembl:ENST00000335135(transcript)|ensembl:ENST00000622443(transcript)|ensembl:ENST00000647274(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001947"(heart looping)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003190"(atrioventricular valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0033189"(response to vitamin A)|go:"GO:0035054"(embryonic heart tube anterior/posterior pattern specification)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR008013(GATA-type transcription activator, N-terminal)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR016375(Transcription factor GATA-4/5/6)|interpro:IPR039355|mint:P43694|rcsb pdb:2M9W|reactome:R-HSA-2032785|reactome:R-HSA-400511|reactome:R-HSA-5578768|reactome:R-HSA-9690406|reactome:R-HSA-983231|refseq:XP_016868801.1|refseq:NP_002043.2|refseq:XP_005272442.1|refseq:XP_005272443.1|refseq:XP_006716311.1 - - function:"Defects in GATA4 are the cause of atrial septal defect type 2 (ASD2) [MIM:607941]. ASD2 is a congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. ASD2 patients show other heart abnormalities including ventricular and atrioventricular septal defects, pulmonary valve thickening or insufficiency of the cardiac valves. ASD2 is not associated with defects in the cardiac conduction system or non-cardiac abnormalities"|comment:mint|function:Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:lzfeBDLcKGZXrcnJzaVRQrJnfpE9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q5T0B9 intact:EBI-25410216 intact:EBI-1210594|uniprotkb:Q8WYU4|intact:EBI-28970502|ensembl:ENSP00000362527|ensembl:ENSP00000446335 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:zn362_human(display_long)|uniprotkb:ZNF362(gene name)|psi-mi:ZNF362(display_short)|uniprotkb:PP6997(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) ensembl:ENSP00000362527|ensembl:ENSP00000446335|refseq:NP_689706.2|refseq:XP_016855904.1|ensembl:ENSG00000160094(gene)|ensembl:ENST00000373428(transcript)|ensembl:ENST00000539719(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:LoTlvHm4JVeiU22UPPI13iierAo9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9UL40 intact:EBI-25410216 intact:EBI-2462313|uniprotkb:B7Z367|uniprotkb:Q68CV9|uniprotkb:Q6ZMW1|ensembl:ENSP00000350869 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:zn346_human(display_long)|uniprotkb:ZNF346(gene name)|psi-mi:ZNF346(display_short)|uniprotkb:JAZ(gene name synonym)|uniprotkb:Just another zinc finger protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001295142.1|refseq:NP_001295143.1|refseq:NP_001295148.1|refseq:NP_001295152.1|refseq:NP_036411.1|refseq:XP_016864784.1|refseq:XP_016864785.1|ensembl:ENSG00000113761(gene)|ensembl:ENST00000358149(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0035198"(miRNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2MKD|rcsb pdb:2MKN - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:bK/y4NYSSsa1tcNjtbmsEmkSp7Q9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q8N567 intact:EBI-25410216 intact:EBI-5235536|uniprotkb:B2RAE7|uniprotkb:Q9H027|ensembl:ENSP00000254037|ensembl:ENSP00000369546|ensembl:ENSP00000385047|ensembl:ENSP00000412637 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:zchc9_human(display_long)|uniprotkb:ZCCHC9(gene name)|psi-mi:ZCCHC9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001124507.1|refseq:NP_001124508.1|refseq:NP_115656.1|ensembl:ENSG00000131732(gene)|ensembl:ENST00000254037(transcript)|ensembl:ENST00000380199(transcript)|ensembl:ENST00000407610(transcript)|ensembl:ENST00000438268(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR042246 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:M/NIA60lFfPQAjGBMtHILP1zw/s9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q6PJT7 intact:EBI-25410216 intact:EBI-740660|uniprotkb:B4DXU8|uniprotkb:B4DZW7|ensembl:ENSP00000251038|uniprotkb:A8MY46|uniprotkb:Q6MZU4|uniprotkb:Q6PJ32|uniprotkb:Q6PUI6|uniprotkb:Q6PUI8|uniprotkb:Q86TQ5|uniprotkb:Q86TW0|uniprotkb:Q86TW1|uniprotkb:Q8NCZ3|uniprotkb:Q8TDE2|uniprotkb:Q9HAC9|uniprotkb:Q9Y5A0|uniprotkb:Q8NCT6|intact:EBI-2857849|uniprotkb:B4E2H4|uniprotkb:G3V5R4 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:zc3he_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-37(gene name synonym)|uniprotkb:ZC3H14(gene name)|psi-mi:ZC3H14(display_short)|uniprotkb:Mammalian suppressor of tau pathology-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001153575.1|refseq:NP_001153576.1|refseq:NP_079100.2|refseq:NP_997543.1|refseq:NP_997544.1|refseq:NP_997545.2|ensembl:ENSG00000100722(gene)|ensembl:ENST00000251038(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0046872"(metal ion binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR040366|refseq:XP_005268125.1|refseq:NP_001313236.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:X2bh/uBtNVh/Wy30Sk+M3ijrZoM9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q6RFH5 intact:EBI-25410216 intact:EBI-722366|uniprotkb:Q9BRC9|uniprotkb:Q9H6X8|uniprotkb:Q9NVY2|uniprotkb:A8K8G5|ensembl:ENSP00000278856|ensembl:ENSP00000432119|ensembl:ENSP00000435726 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:wdr74_human(display_long)|uniprotkb:NOP seven-associated protein 1(gene name synonym)|uniprotkb:WDR74(gene name)|psi-mi:WDR74(display_short)|uniprotkb:NSA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_060563.2|refseq:XP_005274112.1|refseq:NP_001294906.1|ensembl:ENSG00000133316(gene)|ensembl:ENST00000278856(transcript)|ensembl:ENST00000525239(transcript)|ensembl:ENST00000529106(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037379|mint:Q6RFH5 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:KGh4kcZ85zi1yj6Ow10pW3h7ECM9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9Y2W2 intact:EBI-25410216 intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9ULW0 intact:EBI-25410216 intact:EBI-1037322|uniprotkb:Q9H1R4|uniprotkb:Q9NRA3|uniprotkb:Q9UFN9|uniprotkb:Q9UL00|uniprotkb:Q9Y2M1|intact:EBI-2554635|uniprotkb:Q96RR5|intact:EBI-28976825|ensembl:ENSP00000300403 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:tpx2_human(display_long)|uniprotkb:TPX2(gene name)|psi-mi:TPX2(display_short)|uniprotkb:C20orf1(gene name synonym)|uniprotkb:C20orf2(gene name synonym)|uniprotkb:DIL2(gene name synonym)|uniprotkb:HCA519(gene name synonym)|uniprotkb:Restricted expression proliferation-associated protein 100(gene name synonym)|uniprotkb:Differentially expressed in cancerous and non-cancerous lung cells 2(gene name synonym)|uniprotkb:Protein fls353(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 519(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) dip:DIP-36727N|refseq:NP_036244.2|ensembl:ENSP00000300403|ensembl:ENST00000340513|ensembl:ENSP00000341145|refseq:XP_011526999.1|refseq:XP_011527001.1|dip:DIP-46212N|ensembl:ENSG00000088325(gene)|ensembl:ENST00000300403(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0043203"(axon hillock)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR009675(Targeting for Xklp2)|interpro:IPR015128(Aurora-A binding)|interpro:IPR027329|interpro:IPR027330|mint:Q9ULW0|rcsb pdb:1OL5|rcsb pdb:3E5A|rcsb pdb:3HA6|rcsb pdb:4C3P|rcsb pdb:5LXM|rcsb pdb:6BJC|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|reactome:R-HSA-6804756|reactome:R-HSA-8854518 - - caution:This sequence has been withdrawn from Uniprot. figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:dQbYLMi2nP9JPEbdDMk4R4arVxw9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q8NEF9 intact:EBI-25410216 intact:EBI-2824681|uniprotkb:Q5QFI2|uniprotkb:Q96AH4|uniprotkb:Q96DK2|ensembl:ENSP00000341324 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:srfb1_human(display_long)|uniprotkb:SRFBP1(gene name)|psi-mi:SRFBP1(display_short)|uniprotkb:SRF-dependent transcription regulation-associated protein(gene name synonym)|uniprotkb:p49/STRAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) ensembl:ENSG00000151304(gene)|ensembl:ENST00000339397(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR015158(Bud-site selection protein, BUD22)|interpro:IPR037393|refseq:NP_689759.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:MQv9j4+l9h+7z05X/bRJAompesc9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:O75940 intact:EBI-25410216 intact:EBI-1052641|uniprotkb:Q5T3K6|uniprotkb:D3DRB1|uniprotkb:B2RA27|ensembl:ENSP00000358605|ensembl:ENSP00000358616 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:spf30_human(display_long)|uniprotkb:SMN-related protein(gene name synonym)|uniprotkb:30 kDa splicing factor SMNrp(gene name synonym)|uniprotkb:Survival motor neuron domain-containing protein 1(gene name synonym)|uniprotkb:SMNDC1(gene name)|psi-mi:SMNDC1(display_short)|uniprotkb:SMNR(gene name synonym)|uniprotkb:SPF30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_005862.1|ensembl:ENSG00000119953(gene)|ensembl:ENST00000369592(transcript)|ensembl:ENST00000369603(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:O75940|go:"GO:0006915"(apoptotic process)|rcsb pdb:4A4F|rcsb pdb:4A4H|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:hrp2pNu/wpfPdN/3qdDSwqz1t6Q9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q969G3 intact:EBI-25410216 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q15637 intact:EBI-25410216 intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q15050 intact:EBI-25410216 intact:EBI-749186|uniprotkb:Q9BUX8|ensembl:ENSP00000322396 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:rrs1_human(display_long)|uniprotkb:RRS1(gene name)|psi-mi:RRS1(display_short)|uniprotkb:KIAA0112(gene name synonym)|uniprotkb:RRR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_055984.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007023(Ribosomal biogenesis regulatory protein)|mint:Q15050|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000179041(gene)|ensembl:ENST00000320270(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000794"(condensed nuclear chromosome) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:0Nm9UoIGLBiqOGl0E2BA0S5EXIU9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q8NCN4 intact:EBI-25410216 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9NW64 intact:EBI-25410216 intact:EBI-2602260|uniprotkb:A6NDM5|uniprotkb:O95607|uniprotkb:B4DLI9|ensembl:ENSP00000199814 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:rbm22_human(display_long)|uniprotkb:RBM22(gene name)|psi-mi:RBM22(display_short)|uniprotkb:ZC3H16(gene name synonym)|uniprotkb:RNA-binding motif protein 22(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 16(gene name synonym)|uniprotkb:199G4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_060517.1|go:"GO:0035690"|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|rcsb pdb:2YTC|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|ensembl:ENST00000199814(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000086589(gene)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:PjcPER8I/RBxwu3oACO1LHxzKAM9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:O15514 intact:EBI-25410216 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q96BK5 intact:EBI-25410216 intact:EBI-721782|uniprotkb:Q548A5|uniprotkb:Q7Z7J8|uniprotkb:Q96QD7|uniprotkb:Q9HBU7|uniprotkb:Q6QWG9|uniprotkb:Q9NWW2|uniprotkb:B2R9B1|ensembl:ENSP00000318966 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:pinx1_human(display_long)|uniprotkb:TRF1-interacting protein 1(gene name synonym)|uniprotkb:Liver-related putative tumor suppressor(gene name synonym)|uniprotkb:Protein 67-11-3(gene name synonym)|uniprotkb:PINX1(gene name)|psi-mi:PINX1(display_short)|uniprotkb:LPTS(gene name synonym)|uniprotkb:Pin2-interacting protein X1(gene name synonym)|uniprotkb:LPTL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001271285.1|refseq:NP_060354.4|ensembl:ENSG00000254093(gene)|ensembl:ENST00000314787(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904744"(positive regulation of telomeric DNA binding)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000467(D111/G-patch) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:yiJlriaezXM0DsXk5YzZeNVWdvA9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:O15504 intact:EBI-25410216 intact:EBI-2515057|ensembl:ENSP00000258742|uniprotkb:Q49AE7|uniprotkb:Q9BS49|uniprotkb:A4D143|uniprotkb:B4DP42|intact:EBI-13077614 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:nup42_human(display_long)|uniprotkb:NUP42(gene name)|psi-mi:NUP42(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:NLP-1(gene name synonym)|uniprotkb:NUP42 homolog(gene name synonym)|uniprotkb:NUPL2(gene name synonym)|uniprotkb:Nucleoporin hCG1(gene name synonym)|uniprotkb:Nucleoporin-42(gene name synonym)|uniprotkb:Nucleoporin-like protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) ensembl:ENSG00000136243(gene)|ensembl:ENST00000258742(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|interpro:IPR000571(Zinc finger, CCCH-type)|mint:O15504|rcsb pdb:6B4F|rcsb pdb:6B4I|rcsb pdb:6B4J|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-3108214|refseq:NP_031368.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:31NO/6++LYM1UsI/mSVr0bsM1to9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:P52948 intact:EBI-25410216 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9UKX7 intact:EBI-25410216 intact:EBI-2371082|uniprotkb:O75644|uniprotkb:Q9NPM9|uniprotkb:Q9NPR6|uniprotkb:Q9P1K5|uniprotkb:B2RB15|uniprotkb:B1AHA4|uniprotkb:Q8N6V5|ensembl:ENSP00000345895 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:nup50_human(display_long)|uniprotkb:NUP50(gene name)|psi-mi:NUP50(display_short)|uniprotkb:NPAP60L(gene name synonym)|uniprotkb:Nuclear pore-associated protein 60 kDa-like(gene name synonym)|uniprotkb:PRO1146(orf name)|uniprotkb:Nucleoporin Nup50(gene name synonym)|uniprotkb:50 kDa nucleoporin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:XP_011528135.1|refseq:NP_009103.2|refseq:NP_705931.1|refseq:XP_006724166.1|refseq:XP_006724167.1|refseq:XP_005261369.1|refseq:XP_005261371.1|refseq:XP_016884026.1|ensembl:ENSG00000093000(gene)|ensembl:ENST00000347635(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|mint:Q9UKX7|rcsb pdb:2EC1|rcsb pdb:3TJ3|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:tg/qpkdGAm/M6vLvvCzdTCZoxiA9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q8NFH5 intact:EBI-25410216 intact:EBI-9050429|uniprotkb:B4DP57|uniprotkb:B4DYB4|uniprotkb:Q4ZFZ9|uniprotkb:Q53S95|uniprotkb:Q8TDJ1|ensembl:ENSP00000295119 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:nup35_human(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:NUP35(gene name)|psi-mi:NUP35(display_short)|uniprotkb:MP44(gene name synonym)|uniprotkb:NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Mitotic phosphoprotein 44(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:XP_006712317.1|refseq:XP_011508878.1|refseq:XP_011508879.1|refseq:NP_001274513.1|refseq:NP_612142.2|refseq:NP_001274514.1|dip:DIP-47308N|ensembl:ENSG00000163002(gene)|ensembl:ENST00000295119(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|mint:Q8NFH5|rcsb pdb:4LIR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:oFL2V05tM9dYT+fjUiqMLwxZYr89606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9UMY1 intact:EBI-25410216 intact:EBI-2862609|uniprotkb:Q9Y3U7|uniprotkb:Q5T297|ensembl:ENSP00000405674 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:nol7_human(display_long)|uniprotkb:NOL7(gene name)|psi-mi:NOL7(display_short)|uniprotkb:C6orf90(gene name synonym)|uniprotkb:NOP27(gene name synonym)|uniprotkb:Nucleolar protein of 27 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_057251.2|refseq:NP_001304653.1|ensembl:ENSG00000225921(gene)|ensembl:ENST00000451315(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|interpro:IPR012579(NUC129)|interpro:IPR039626|mint:Q9UMY1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:4I1C2wd0qGg9CWZDodm/Bp+tptA9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:P48681 intact:EBI-25410216 intact:EBI-10966836|ensembl:ENSP00000357206|uniprotkb:Q5SYZ6|uniprotkb:Q3LIF5|uniprotkb:O00552 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:nest_human(display_long)|uniprotkb:NES(gene name)|psi-mi:NES(display_short)|uniprotkb:Nbla00170(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_006608.1|ensembl:ENSG00000132688(gene)|ensembl:ENST00000368223(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030844"(positive regulation of intermediate filament depolymerization)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0072089"(stem cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR018039|interpro:IPR031211|interpro:IPR039008|mint:P48681 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:IEPf+MleiqNi+QAX57rAn4tYId09606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:O95983 intact:EBI-25410216 intact:EBI-1783068|uniprotkb:Q6PIL9|uniprotkb:Q6PJZ9|uniprotkb:Q86XF4|uniprotkb:A8K4B7|uniprotkb:D6W5Z2|ensembl:ENSP00000412302 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:mbd3_human(display_long)|uniprotkb:MBD3(gene name)|psi-mi:MBD3(display_short)|uniprotkb:Methyl-CpG-binding protein MBD3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001268382.1|refseq:NP_001268383.1|dip:DIP-46517N|ensembl:ENSG00000071655(gene)|ensembl:ENST00000434436(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009888"(tissue development)|go:"GO:0016573"(histone acetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0048568"(embryonic organ development)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|interpro:IPR037965|mint:O95983|rcsb pdb:2MB7|rcsb pdb:6CC8|rcsb pdb:6CCG|rcsb pdb:6CEU|rcsb pdb:6CEV|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:lm8jh0YVLdljXDhjkTm9B1YSsWA9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q5SSJ5 intact:EBI-25410216 intact:EBI-2880687|ensembl:ENSP00000312625|ensembl:ENSP00000403039|uniprotkb:Q5SWC6|uniprotkb:Q6PIM9|uniprotkb:B3KMZ8|uniprotkb:A8K5D7|uniprotkb:Q8NDF0|uniprotkb:Q05BI0|uniprotkb:B4E210|uniprotkb:A6NI71|uniprotkb:Q9UHY0|uniprotkb:Q5SSJ6 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:hp1b3_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short)|uniprotkb:Protein HP1-BP74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) ensembl:ENSG00000127483(gene)|ensembl:ENST00000312239(transcript)|ensembl:ENST00000438032(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|mint:Q5SSJ5|rcsb pdb:2RQP|go:"GO:0005694"(chromosome)|refseq:XP_016856882.1|refseq:XP_016856883.1|refseq:XP_011539834.1|refseq:XP_011539835.1|refseq:XP_011539836.1|refseq:NP_057371.2|refseq:XP_005245932.1|refseq:XP_005245933.1|refseq:XP_005245934.1|refseq:XP_005245935.1|refseq:XP_005245936.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:kLFithZZv+Qn9YLElEnX81awKDw9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:P05114 intact:EBI-25410216 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q86YP4 intact:EBI-25410216 intact:EBI-726224|uniprotkb:Q7L3J2|uniprotkb:Q96F28|uniprotkb:Q9NPU2|uniprotkb:Q9NXS1|uniprotkb:B5MC40|ensembl:ENSP00000351552|ensembl:ENSP00000353463 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:p66a_human(display_long)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym)|uniprotkb:GATAD2A(gene name)|psi-mi:GATAD2A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_060130.3|refseq:NP_001287875.1|refseq:XP_011526407.1|ensembl:ENSG00000167491(gene)|ensembl:ENST00000358713(transcript)|ensembl:ENST00000360315(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q86YP4|rcsb pdb:2L2L|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|dip:DIP-36053N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:s2G27yMihH9d7ny/v1GZ7aeTpDQ9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q96QD9 intact:EBI-25410216 intact:EBI-724553|uniprotkb:Q96SL9|uniprotkb:Q9BQI8|uniprotkb:A8MY74|uniprotkb:B2RCB2|uniprotkb:B7Z3R4|uniprotkb:B7Z7V1|uniprotkb:B7Z8I0|uniprotkb:B7ZAJ3|uniprotkb:C9J7P6|uniprotkb:C9JNG6|uniprotkb:C9JTH3|uniprotkb:C9JY50|ensembl:ENSP00000241502 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:uif_human(display_long)|uniprotkb:UIF(gene name synonym)|uniprotkb:FYTTD1(gene name)|psi-mi:FYTTD1(display_short)|uniprotkb:Forty-two-three domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001011537.2|refseq:NP_115664.2|ensembl:ENSG00000122068(gene)|ensembl:ENST00000241502(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016607"(nuclear speck)|interpro:IPR009782(Protein of unknown function DUF1346)|mint:Q96QD9|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|dip:DIP-62119N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:mMARxli9v/w8ggb5tjd/5hvSxnI9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q99848 intact:EBI-25410216 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q96DF8 intact:EBI-25410216 intact:EBI-3928124|uniprotkb:Q49AH7|uniprotkb:Q9BTZ4|ensembl:ENSP00000252137 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:ess2_human(display_long)|uniprotkb:ESS2(gene name)|psi-mi:ESS2(display_short)|uniprotkb:DGCR13(gene name synonym)|uniprotkb:DGCR14(gene name synonym)|uniprotkb:DGSH(gene name synonym)|uniprotkb:DGSI(gene name synonym)|uniprotkb:DiGeorge syndrome critical region 13(gene name synonym)|uniprotkb:DiGeorge syndrome critical region 14(gene name synonym)|uniprotkb:DiGeorge syndrome protein H(gene name synonym)|uniprotkb:ES2(gene name synonym)|uniprotkb:Protein ES2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) ensembl:ENSG00000100056(gene)|ensembl:ENST00000252137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0007399"(nervous system development)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR019148|ensembl:ENSP00000252137|refseq:NP_073210.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:4FNOVEs4KXbqLkXlGksstSsL2qs9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9P013 intact:EBI-25410216 intact:EBI-2371709|uniprotkb:B2RC17|uniprotkb:Q05BV9|uniprotkb:Q05DM1|uniprotkb:Q9UI29|ensembl:ENSP00000475615 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:cwc15_human(display_long)|uniprotkb:CWC15(gene name)|psi-mi:CWC15(display_short)|uniprotkb:C11orf5(gene name synonym)|uniprotkb:AD-002(orf name)|uniprotkb:HSPC148(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:XP_011541170.1|refseq:NP_057487.2|refseq:XP_016873405.1|ensembl:ENSG00000150316(gene)|ensembl:ENST00000279839(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006973(Cwf15/Cwc15 cell cycle control protein)|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:Sq0ehGSKIEKx1X9xv4Nx0ZiqXhk9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q96FF9 intact:EBI-25410216 intact:EBI-718805|uniprotkb:A8K625|ensembl:ENSP00000275517 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:cdca5_human(display_long)|uniprotkb:Cell division cycle-associated protein 5(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:CDCA5(gene name)|psi-mi:CDCA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_542399.1|ensembl:ENSG00000146670(gene)|ensembl:ENST00000275517(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0071922"(regulation of cohesin loading)|interpro:IPR018605|mint:Q96FF9|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2500257|dip:DIP-47377N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:G1O3J3WI+SQTuGjjdkUwYeeUaV49606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9H6F5 intact:EBI-25410216 intact:EBI-721289|uniprotkb:B4DY99|ensembl:ENSP00000227520 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:ccd86_human(display_long)|uniprotkb:Cytokine-induced protein with coiled-coil domain(gene name synonym)|uniprotkb:CYCLON(gene name synonym)|uniprotkb:CCDC86(gene name)|psi-mi:CCDC86(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_077003.1|ensembl:ENSG00000110104(gene)|ensembl:ENST00000227520(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR005579(Cgr1)|interpro:IPR026570|mint:Q9H6F5 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:dRd5UWPzAehh8OFqkWrMMCnYYug9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q6PK04 intact:EBI-25410216 intact:EBI-714654|ensembl:ENSP00000329360|ensembl:ENSP00000458884 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:cc137_human(display_long)|uniprotkb:CCDC137(gene name)|psi-mi:CCDC137(display_short)|uniprotkb:cPERP-B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_954981.1|ensembl:ENSG00000185298(gene)|ensembl:ENST00000329214(transcript)|ensembl:ENST00000575223(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|interpro:IPR026680|mint:Q6PK04 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:e64Y/4oJpFqmYZEO1lOUHeLwy0I9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q8WUD4 intact:EBI-25410216 intact:EBI-2557572|uniprotkb:Q8N8I4|ensembl:ENSP00000416263|ensembl:ENSP00000508011 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:ccd12_human(display_long)|uniprotkb:CCDC12(gene name)|psi-mi:CCDC12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001264003.1|ensembl:ENSG00000160799(gene)|ensembl:ENST00000425441(transcript)|ensembl:ENST00000683445(transcript)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR013169(mRNA splicing factor, Cwf18) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:16vIw/KxxolqtfnUJJNMs3Olklg9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q9NZ63 intact:EBI-25410216 intact:EBI-2557577|uniprotkb:Q9NT39|uniprotkb:Q8WVU6|uniprotkb:B3KPX8|ensembl:ENSP00000361524 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:tls1_human(display_long)|uniprotkb:C9orf78(gene name)|psi-mi:C9orf78(display_short)|uniprotkb:HCA59(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 59(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_057604.1|ensembl:ENSG00000136819(gene)|ensembl:ENST00000372447(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|interpro:IPR010756(Hepatocellular carcinoma-associated antigen 59) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:1ypLqEYpSrrqHknZqoOuZCn3NPA9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q7Z6I8 intact:EBI-25410216 intact:EBI-9995695|uniprotkb:D3DQA7|uniprotkb:Q86Y53|uniprotkb:Q8N1T9|ensembl:ENSP00000337044|ensembl:ENSP00000378427|ensembl:ENSP00000395764 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:ce024_human(display_long)|uniprotkb:C5orf24(gene name)|psi-mi:C5orf24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001129058.1|refseq:NP_001287823.1|refseq:NP_689622.2|refseq:XP_005271946.1|refseq:XP_016864538.1|refseq:XP_016864539.1|ensembl:ENSG00000181904(gene)|ensembl:ENST00000338051(transcript)|ensembl:ENST00000394976(transcript)|ensembl:ENST00000435259(transcript)|interpro:IPR040419 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:Ye+nbD86YyjmFkryW2orfM3Wh4w9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q1ED39 intact:EBI-25410216 intact:EBI-9977982|uniprotkb:O43328|uniprotkb:Q5FWF3|ensembl:ENSP00000219837 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:knop1_human(display_long)|uniprotkb:KNOP1(gene name)|psi-mi:KNOP1(display_short)|uniprotkb:C16orf88(gene name synonym)|uniprotkb:FAM191A(gene name synonym)|uniprotkb:TSG118(gene name synonym)|uniprotkb:Protein FAM191A(gene name synonym)|uniprotkb:Testis-specific gene 118 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001013009.2|refseq:NP_001335457.1|refseq:NP_001335458.1|refseq:NP_001335459.1|refseq:NP_001335460.1|ensembl:ENSG00000103550(gene)|ensembl:ENST00000219837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR028124 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:DbTowYDo0km0cUlAS8TTL5JIyyQ9606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IW93-1 uniprotkb:Q8IVW6 intact:EBI-25410216 intact:EBI-5458329|uniprotkb:O95443|uniprotkb:Q59HC9|uniprotkb:Q6P9C9|ensembl:ENSP00000477878 psi-mi:q8iw931(display_long)|uniprotkb:ARHGEF19(gene name)|psi-mi:ARHGEF19(display_short) psi-mi:ari3b_human(display_long)|uniprotkb:ARID3B(gene name)|psi-mi:ARID3B(display_short)|uniprotkb:BDP(gene name synonym)|uniprotkb:DRIL2(gene name synonym)|uniprotkb:Bright and dead ringer protein(gene name synonym)|uniprotkb:Bright-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410221|imex:IM-26436-172 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8IW93-1(isoform-parent) refseq:NP_001294868.1|refseq:NP_006456.1|ensembl:ENSG00000179361(gene)|ensembl:ENST00000622429(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|mint:Q8IVW6|interpro:IPR036431 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XVGLoKdF1sPt0ldRsV1otDW/2Iw9606 rogid:wlZYnH9qjM7VzFUtrNLlqJhRXx49606 rigid:4qSv7jWpRNt/tenlqRboa7EhlPc false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PE2 uniprotkb:Q9NZR1 intact:EBI-7543347|uniprotkb:Q9Y4G3|intact:MINT-3974886|uniprotkb:Q86XU2|uniprotkb:Q8N2S0|uniprotkb:B2RP20|intact:EBI-28979167|ensembl:ENSP00000263674 intact:EBI-4289968|uniprotkb:B4DEW6|ensembl:ENSP00000249700 psi-mi:arhgh_human(display_long)|uniprotkb:KIAA0337(gene name synonym)|uniprotkb:ARHGEF17(gene name)|psi-mi:ARHGEF17(display_short)|uniprotkb:TEM4(gene name synonym)|uniprotkb:164 kDa Rho-specific guanine-nucleotide exchange factor(gene name synonym)|uniprotkb:Tumor endothelial marker 4(gene name synonym) psi-mi:tmod2_human(display_long)|uniprotkb:TMOD2(gene name)|psi-mi:TMOD2(display_short)|uniprotkb:NTMOD(gene name synonym)|uniprotkb:Neuronal tropomodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410309|imex:IM-26436-96 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000263674|refseq:NP_055601.2|ensembl:ENSG00000110237(gene)|ensembl:ENST00000263674(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039917|interpro:IPR039919|mint:Q96PE2|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0005829"(cytosol) ensembl:ENSG00000128872(gene)|ensembl:ENST00000249700(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030426"(growth cone)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051694"(pointed-end actin filament capping)|interpro:IPR004934(Tropomodulin)|interpro:IPR030130|interpro:IPR032675|reactome:R-HSA-390522|refseq:NP_001136357.1|refseq:NP_055363.1 - function:"Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases"|comment:mint|comment:homomint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:m/ZkY14fd55fJwclPYDgHPqFmeU9606 rogid:km9yOQf3wlXkMxXa/wKFxquWej09606 rigid:uZx+o8vuoiljoeYFW0v+Rc2nLfA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PE2 uniprotkb:Q13162 intact:EBI-7543347|uniprotkb:Q9Y4G3|intact:MINT-3974886|uniprotkb:Q86XU2|uniprotkb:Q8N2S0|uniprotkb:B2RP20|intact:EBI-28979167|ensembl:ENSP00000263674 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:arhgh_human(display_long)|uniprotkb:KIAA0337(gene name synonym)|uniprotkb:ARHGEF17(gene name)|psi-mi:ARHGEF17(display_short)|uniprotkb:TEM4(gene name synonym)|uniprotkb:164 kDa Rho-specific guanine-nucleotide exchange factor(gene name synonym)|uniprotkb:Tumor endothelial marker 4(gene name synonym) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410309|imex:IM-26436-96 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000263674|refseq:NP_055601.2|ensembl:ENSG00000110237(gene)|ensembl:ENST00000263674(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039917|interpro:IPR039919|mint:Q96PE2|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0005829"(cytosol) refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695 - function:"Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases"|comment:mint|comment:homomint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:m/ZkY14fd55fJwclPYDgHPqFmeU9606 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 rigid:uZx+o8vuoiljoeYFW0v+Rc2nLfA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PE2 uniprotkb:P32119 intact:EBI-7543347|uniprotkb:Q9Y4G3|intact:MINT-3974886|uniprotkb:Q86XU2|uniprotkb:Q8N2S0|uniprotkb:B2RP20|intact:EBI-28979167|ensembl:ENSP00000263674 intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:arhgh_human(display_long)|uniprotkb:KIAA0337(gene name synonym)|uniprotkb:ARHGEF17(gene name)|psi-mi:ARHGEF17(display_short)|uniprotkb:TEM4(gene name synonym)|uniprotkb:164 kDa Rho-specific guanine-nucleotide exchange factor(gene name synonym)|uniprotkb:Tumor endothelial marker 4(gene name synonym) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410309|imex:IM-26436-96 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000263674|refseq:NP_055601.2|ensembl:ENSG00000110237(gene)|ensembl:ENST00000263674(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039917|interpro:IPR039919|mint:Q96PE2|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0005829"(cytosol) refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 - function:"Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases"|comment:mint|comment:homomint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:m/ZkY14fd55fJwclPYDgHPqFmeU9606 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 rigid:uZx+o8vuoiljoeYFW0v+Rc2nLfA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PE2 uniprotkb:O43663 intact:EBI-7543347|uniprotkb:Q9Y4G3|intact:MINT-3974886|uniprotkb:Q86XU2|uniprotkb:Q8N2S0|uniprotkb:B2RP20|intact:EBI-28979167|ensembl:ENSP00000263674 intact:EBI-741137|ensembl:ENSP00000377793|uniprotkb:Q9BSB6|uniprotkb:A6NC44|uniprotkb:B4DLR1|intact:EBI-11127601|uniprotkb:H9KV59 psi-mi:arhgh_human(display_long)|uniprotkb:KIAA0337(gene name synonym)|uniprotkb:ARHGEF17(gene name)|psi-mi:ARHGEF17(display_short)|uniprotkb:TEM4(gene name synonym)|uniprotkb:164 kDa Rho-specific guanine-nucleotide exchange factor(gene name synonym)|uniprotkb:Tumor endothelial marker 4(gene name synonym) psi-mi:prc1_human(display_long)|uniprotkb:PRC1(gene name)|psi-mi:PRC1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410309|imex:IM-26436-96 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000263674|refseq:NP_055601.2|ensembl:ENSG00000110237(gene)|ensembl:ENST00000263674(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039917|interpro:IPR039919|mint:Q96PE2|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0005829"(cytosol) refseq:NP_003972.1|ensembl:ENSG00000198901(gene)|ensembl:ENST00000394249(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0051301"(cell division)|go:"GO:0070938"(contractile ring)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR007145(MAP65/ASE1)|interpro:IPR032921|mint:O43663|rcsb pdb:3NRX|rcsb pdb:3NRY|rcsb pdb:4L3I|rcsb pdb:4L6Y|rcsb pdb:5KMG|reactome:R-HSA-5625900|go:"GO:0019894"(kinesin binding)|refseq:NP_001254509.1|dip:DIP-34436N - function:"Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases"|comment:mint|comment:homomint crc64:28393C5B1B3662F3 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:m/ZkY14fd55fJwclPYDgHPqFmeU9606 rogid:AV2d6TYVsFn2J598pi/GmPdgK7A9606 rigid:uZx+o8vuoiljoeYFW0v+Rc2nLfA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PE2 uniprotkb:P06396 intact:EBI-7543347|uniprotkb:Q9Y4G3|intact:MINT-3974886|uniprotkb:Q86XU2|uniprotkb:Q8N2S0|uniprotkb:B2RP20|intact:EBI-28979167|ensembl:ENSP00000263674 intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8 psi-mi:arhgh_human(display_long)|uniprotkb:KIAA0337(gene name synonym)|uniprotkb:ARHGEF17(gene name)|psi-mi:ARHGEF17(display_short)|uniprotkb:TEM4(gene name synonym)|uniprotkb:164 kDa Rho-specific guanine-nucleotide exchange factor(gene name synonym)|uniprotkb:Tumor endothelial marker 4(gene name synonym) psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410309|imex:IM-26436-96 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000263674|refseq:NP_055601.2|ensembl:ENSG00000110237(gene)|ensembl:ENST00000263674(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035899|interpro:IPR036322|interpro:IPR039917|interpro:IPR039919|mint:Q96PE2|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0005829"(cytosol) refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N - function:"Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases"|comment:mint|comment:homomint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:m/ZkY14fd55fJwclPYDgHPqFmeU9606 rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606 rigid:uZx+o8vuoiljoeYFW0v+Rc2nLfA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q70Z35-1 uniprotkb:P49902 intact:EBI-25410325|ensembl:ENSP00000288368 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:q70z35-1(display_long)|uniprotkb:DEP domain-containing protein 2(gene name synonym)|uniprotkb:PREX2(gene name)|psi-mi:PREX2(display_short)|uniprotkb:DEPDC2(gene name synonym)|uniprotkb:P-Rex2(isoform synonym) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410333|imex:IM-26436-260 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1790593(isoform-parent)|ensembl:ENSG00000046889(gene)|ensembl:ENST00000288368(transcript) ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:rCC+SJ4ItEfhEXK/YAIoyCiN+2k9606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 rigid:5BbBuqugo4WW0Q3RJ3bkS/21mgE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q70Z35-1 uniprotkb:Q8N392 intact:EBI-25410325|ensembl:ENSP00000288368 intact:EBI-372814|uniprotkb:E1P575|uniprotkb:Q58EZ3|uniprotkb:Q6P679|uniprotkb:Q6PJD7|uniprotkb:Q96S64|intact:EBI-28984395|ensembl:ENSP00000357131 psi-mi:q70z35-1(display_long)|uniprotkb:DEP domain-containing protein 2(gene name synonym)|uniprotkb:PREX2(gene name)|psi-mi:PREX2(display_short)|uniprotkb:DEPDC2(gene name synonym)|uniprotkb:P-Rex2(isoform synonym) psi-mi:rhg18_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym)|uniprotkb:MacGAP(gene name synonym)|uniprotkb:ARHGAP18(gene name)|psi-mi:ARHGAP18(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410333|imex:IM-26436-260 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1790593(isoform-parent)|ensembl:ENSG00000046889(gene)|ensembl:ENST00000288368(transcript) refseq:NP_277050.2|ensembl:ENSP00000357131|ensembl:ENSG00000146376(gene)|ensembl:ENST00000368149(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:2000145"(regulation of cell motility) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:rCC+SJ4ItEfhEXK/YAIoyCiN+2k9606 rogid:24F0Swg/Ye/UfWPt8fJcO+q0nkc9606 rigid:5BbBuqugo4WW0Q3RJ3bkS/21mgE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:P34897 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q5T3J3 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q96EL3 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-2513715|ensembl:ENSP00000258105 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:rm53_human(display_long)|uniprotkb:MRPL53(gene name)|psi-mi:MRPL53(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 ensembl:ENSG00000204822(gene)|ensembl:ENST00000258105(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR019716|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7A5J|refseq:NP_444278.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:+P6xCKwzJVVQv/StyLhlLH9NkgA9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q8IWI9 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:P10515 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-2959723|ensembl:ENSP00000280346|uniprotkb:Q16783|uniprotkb:Q53EP3 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:odp2_human(display_long)|uniprotkb:DLAT(gene name)|psi-mi:DLAT(display_short)|uniprotkb:DLTA(gene name synonym)|uniprotkb:70 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:M2 antigen complex 70 kDa subunit(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_001922.2|ensembl:ENSG00000150768(gene)|ensembl:ENST00000280346(transcript)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P10515|rcsb pdb:1FYC|rcsb pdb:1Y8N|rcsb pdb:1Y8O|rcsb pdb:1Y8P|rcsb pdb:2DNE|rcsb pdb:2PNR|rcsb pdb:2Q8I|rcsb pdb:3B8K|rcsb pdb:3CRK|rcsb pdb:3CRL|rcsb pdb:6CT0|rcsb pdb:6H55|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268|dip:DIP-29496N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:Owh80Cm4CXvo2rPKUhLGc/U47co9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q15750 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-358643|uniprotkb:Q2PP09|intact:EBI-3959873|uniprotkb:Q8IZW2|ensembl:ENSP00000216160 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:tab1_human(display_long)|uniprotkb:TAB1(gene name)|psi-mi:TAB1(display_short)|uniprotkb:MAP3K7IP1(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_006107.1|refseq:NP_705717.1|ensembl:ENSP00000216160|ensembl:ENST00000331454|ensembl:ENSP00000333049|go:"GO:0003279"(cardiac septum development)|rcsb pdb:7NTI|go:"GO:0003007"(heart morphogenesis)|ensembl:ENSG00000100324(gene)|ensembl:ENST00000216160(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0060976"(coronary vasculature development)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q15750|rcsb pdb:2J4O|rcsb pdb:2POM|rcsb pdb:2POP|rcsb pdb:2YDS|rcsb pdb:2YIY|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4GS6|rcsb pdb:4KA3|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5DIY|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5V5N|rcsb pdb:5VVU|rcsb pdb:7NTH|reactome:R-HSA-168638|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27524N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:28+bzs6bpXJTun4XukxC/7oAYSs9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q13425 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:SABgmvArdLH93OpFobs/L3BleVY9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q15459 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q14160 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:P62979 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q5HYI8 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-2824032|uniprotkb:Q8WUD3|ensembl:ENSP00000273375 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:rabl3_human(display_long)|uniprotkb:RABL3(gene name)|psi-mi:RABL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 ensembl:ENSG00000144840(gene)|ensembl:ENST00000273375(transcript)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0030183"(B cell differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:1903059"(regulation of protein lipidation)|interpro:IPR027417|mint:Q5HYI8|go:"GO:0050821"(protein stabilization)|refseq:NP_776186.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:wa/T6PILk7wiphCKdnT3OidKB0E9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q9Y2J2 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158|uniprotkb:B7Z4I5|uniprotkb:F5GX05 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397(gene)|ensembl:ENST00000341928(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q12959 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:P48047 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q9P2R3 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:237ungtRc80jqTOKBUnFX9qDUGw9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VV41 uniprotkb:Q8NI60 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739 psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410343|imex:IM-26436-314 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606 rigid:S6sV96eP+3ZDmSVeP3VEoPVgZ/M false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:P04350 intact:EBI-25410381 intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q9NZ01 intact:EBI-25410381 intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:P51571 intact:EBI-25410381 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:P62306 intact:EBI-25410381 intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:P53985 intact:EBI-25410381 intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|uniprotkb:Q49A45|ensembl:ENSP00000416167|ensembl:ENSP00000441065|ensembl:ENSP00000485688|ensembl:ENSP00000358640|ensembl:ENSP00000397106|ensembl:ENSP00000399104|ensembl:ENSP00000486000|ensembl:ENSP00000505879 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|ensembl:ENSG00000155380(gene)|ensembl:ENSG00000281917(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032094"(response to food)|ensembl:ENST00000369626(transcript)|ensembl:ENST00000429288(transcript)|ensembl:ENST00000443580(transcript)|ensembl:ENST00000458229(transcript)|ensembl:ENST00000538576(transcript)|ensembl:ENST00000628110(transcript)|ensembl:ENST00000630362(transcript)|ensembl:ENST00000679803(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015130"(mevalonate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0015728"(mevalonate transport)|go:"GO:0016020"(membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051780"(behavioral response to nutrient)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|mint:P53985|go:"GO:1905039"(carboxylic acid transmembrane transport)|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:P04843 intact:EBI-25410381 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q96TA2 intact:EBI-25410381 intact:EBI-2818916|uniprotkb:Q9UMR9|uniprotkb:Q9H1Q0|uniprotkb:Q5T8D9|uniprotkb:D3DRV8|uniprotkb:D3DRV9|uniprotkb:B4DNM1|intact:EBI-10989776|ensembl:ENSP00000318480 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:ymel1_human(display_long)|uniprotkb:YME1L1(gene name)|psi-mi:YME1L1(display_short)|uniprotkb:FTSH1(gene name synonym)|uniprotkb:YME1L(gene name synonym)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:Meg-4(gene name synonym)|uniprotkb:Presenilin-associated metalloprotease(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:UNQ1868/PRO4304(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_647473.1|refseq:NP_055078.1|refseq:NP_001240795.1|ensembl:ENSG00000136758(gene)|ensembl:ENST00000326799(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q96TA2|reactome:R-HSA-8949664 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:73ThpwDPUEO7f5SBfSljmbwJLn09606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q9Y277 intact:EBI-25410381 intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668(gene)|ensembl:ENST00000022615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015853"(adenine transport)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030271|mint:Q9Y277|reactome:R-HSA-5689880|reactome:R-HSA-8949215 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:O14925 intact:EBI-25410381 intact:EBI-1047996|uniprotkb:Q53FF8|uniprotkb:Q6P5S5|uniprotkb:Q5T1E6|ensembl:ENSP00000464522 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:tim23_human(display_long)|uniprotkb:TIMM23(gene name)|psi-mi:TIMM23(display_short)|uniprotkb:TIM23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_006318.1|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|interpro:IPR005681(Mitochondrial import inner membrane translocase, subunit Tim23)|mint:O14925|reactome:R-HSA-1268020|ensembl:ENSG00000265354(gene)|ensembl:ENST00000580018(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:Hmu/kwfaPLGFGYBJH0oue7JDYqM9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q15599 intact:EBI-25410381 intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005|intact:EBI-15579694 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:nhrf2_human(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|ensembl:ENSG00000065054(gene)|ensembl:ENST00000424542(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031197|interpro:IPR036034|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|go:"GO:0042802"(identical protein binding)|dip:DIP-29093N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q9H936 intact:EBI-25410381 intact:EBI-1050588|uniprotkb:Q8TBU8|uniprotkb:A8K366|uniprotkb:C9J1H6|uniprotkb:E9PJD3|uniprotkb:E9PKB2|uniprotkb:E9PL68|uniprotkb:E9PN26|uniprotkb:E9PNQ3|uniprotkb:E9PP01|uniprotkb:E9PR97|ensembl:ENSP00000322020|ensembl:ENSP00000437236|ensembl:ENSP00000486058 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:ghc1_human(display_long)|uniprotkb:"Glutamate/H(+) symporter 1"(gene name synonym)|uniprotkb:Solute carrier family 25 member 22(gene name synonym)|uniprotkb:SLC25A22(gene name)|psi-mi:SLC25A22(display_short)|uniprotkb:GC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001177989.1|refseq:NP_001177990.1|refseq:NP_078974.1|ensembl:ENSG00000177542(gene)|ensembl:ENST00000320230(transcript)|ensembl:ENST00000531214(transcript)|ensembl:ENST00000628067(transcript)|go:"GO:0005280"("amino acid:proton symporter activity")|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-HSA-428643|refseq:XP_011518671.1|refseq:XP_011518672.1|refseq:XP_011518673.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:B1e6uu3Vx73qy/JrHS7p63p0QMM9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q15459 intact:EBI-25410381 intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q16181 intact:EBI-25410381 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q14498 intact:EBI-25410381 intact:EBI-395290|uniprotkb:A5D8W2|uniprotkb:B0BLV3|uniprotkb:Q14499|uniprotkb:A2RRD3|uniprotkb:E1P5S0|uniprotkb:E1P5S1|ensembl:ENSP00000253363 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:rbm39_human(display_long)|uniprotkb:HCC1(gene name synonym)|uniprotkb:RBM39(gene name)|psi-mi:RBM39(display_short)|uniprotkb:RNA-binding motif protein 39(gene name synonym)|uniprotkb:RNA-binding region-containing protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 1(gene name synonym)|uniprotkb:Splicing factor HCC1(gene name synonym)|uniprotkb:RNPC2(gene name synonym)|uniprotkb:CAPER alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001229528.1|refseq:NP_001229529.1|refseq:NP_004893.1|refseq:NP_909122.1|ensembl:ENSG00000131051(gene)|ensembl:ENST00000253363(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006509(Splicing factor, CC1-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029123|interpro:IPR035979|mint:Q14498|rcsb pdb:2JRS|rcsb pdb:2MHN|rcsb pdb:4OO6|rcsb pdb:4OZ0|rcsb pdb:4OZ1|rcsb pdb:4YUD|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|dip:DIP-32928N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:/e7HNZt0CtcDKTwF8BqSwNpyufc9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:O43251 intact:EBI-25410381 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q3KR16 intact:EBI-25410381 intact:EBI-10240979|uniprotkb:Q9NVK9|uniprotkb:Q3SWR1|uniprotkb:Q9H8F4|uniprotkb:Q8N1P1|uniprotkb:Q8WYY1|ensembl:ENSP00000011684|ensembl:ENSP00000380185|ensembl:ENSP00000506982 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:pkhg6_human(display_long)|uniprotkb:PLEKHG6(gene name)|psi-mi:PLEKHG6(display_short)|uniprotkb:Myosin-interacting guanine nucleotide exchange factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001138328.1|refseq:NP_001138329.1|refseq:NP_060643.2|refseq:XP_005253761.1|ensembl:ENSG00000008323(gene)|ensembl:ENST00000011684(transcript)|ensembl:ENST00000396988(transcript)|ensembl:ENST00000684764(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0030054"(cell junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR042918|reactome:R-HSA-8980692|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:HfM8hGxyoHU2Q/UiTpyfDz/+JBc9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:O95757 intact:EBI-25410381 intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:P55084 intact:EBI-25410381 intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q92616 intact:EBI-25410381 intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q9NVI1 intact:EBI-25410381 intact:EBI-1013291|uniprotkb:Q96JN1|uniprotkb:Q96ST0|uniprotkb:Q9BT96|uniprotkb:A5YMH4|uniprotkb:A6NJZ0|uniprotkb:A4ZVE4|ensembl:ENSP00000310842 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:fanci_human(display_long)|uniprotkb:FANCI(gene name)|psi-mi:FANCI(display_short)|uniprotkb:KIAA1794(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:XP_011520058.1|refseq:XP_011520059.1|refseq:XP_011520066.1|refseq:NP_001106849.1|refseq:NP_060663.2|dip:DIP-29381N|ensembl:ENSG00000140525(gene)|ensembl:ENST00000310775(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR026171|interpro:IPR029305|interpro:IPR029308|interpro:IPR029310|interpro:IPR029312|interpro:IPR029313|interpro:IPR029314|interpro:IPR029315|mint:Q9NVI1|rcsb pdb:6VAA|rcsb pdb:6VAD|rcsb pdb:6VAE|rcsb pdb:6VAF|rcsb pdb:7AY1|reactome:R-HSA-6783310|reactome:R-HSA-6796648 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:yJJMHIBOVPDIQcCBJ19DGitg3VA9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:O00148 intact:EBI-25410381 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q969X6 intact:EBI-25410381 intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:Q8WUH6 intact:EBI-25410381 intact:EBI-1042811|uniprotkb:B3KMN9|ensembl:ENSP00000280756|ensembl:ENSP00000446537|ensembl:ENSP00000446717|ensembl:ENSP00000449106|ensembl:ENSP00000449785|ensembl:ENSP00000450350 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:tm263_human(display_long)|uniprotkb:TMEM263(gene name)|psi-mi:TMEM263(display_short)|uniprotkb:C12orf23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001306590.1|refseq:NP_001306591.1|refseq:NP_001306592.1|refseq:NP_001306593.1|refseq:NP_001306595.1|refseq:NP_689474.1|ensembl:ENSG00000151135(gene)|ensembl:ENST00000280756(transcript)|ensembl:ENST00000547081(transcript)|ensembl:ENST00000547242(transcript)|ensembl:ENST00000548125(transcript)|ensembl:ENST00000550344(transcript)|ensembl:ENST00000551813(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028153 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:7ndvPlnfctdWgCYMvx/yNZ8jyQE9606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R6X4 uniprotkb:P84077 intact:EBI-25410381 intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980 psi-mi:a0a024r6x4_human(display_long)|uniprotkb:PLEKHG4(gene name)|psi-mi:PLEKHG4(display_short)|uniprotkb:hCG_1811728(orf name) psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410401|imex:IM-26436-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|refseq:NP_001123199.1|refseq:NP_001123200.1|refseq:NP_001123201.1|refseq:XP_011521287.1|refseq:XP_011521288.1|refseq:XP_011521289.1|refseq:XP_011521290.1|interpro:IPR036865|interpro:IPR035899|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000219("Dbl homology (DH) domain") refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SnuXZYAmifcqahtFQWTe/ZThU1k9606 rogid:zray9asm6VonxpuJpv0dRBspPt89606 rigid:KdAOiQCrGIrkvcFmTKplPTxNk6U false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q6UXN9 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q9C0J8 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-712637|uniprotkb:Q6NUQ0|uniprotkb:Q587J1|uniprotkb:Q05DP8|uniprotkb:Q53FG9|uniprotkb:Q9NUL1|uniprotkb:Q69YF7|ensembl:ENSP00000325377 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:wdr33_human(display_long)|uniprotkb:WDR33(gene name)|psi-mi:WDR33(display_short)|uniprotkb:WDC146(gene name synonym)|uniprotkb:WD repeat-containing protein 33(gene name synonym)|uniprotkb:WD repeat-containing protein of 146 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:XP_011509738.1|refseq:NP_001006623.1|refseq:NP_060853.3|refseq:NP_001006624.1|ensembl:ENSG00000136709(gene)|ensembl:ENST00000322313(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005581"(collagen trimer)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006301"(postreplication repair)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007283"(spermatogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9C0J8|rcsb pdb:6BLY|rcsb pdb:6BM0|rcsb pdb:6DNH|rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:FzGeASJyKaYaqFQfFBYby692REg9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q13769 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-5280316|uniprotkb:O60839|uniprotkb:Q9UPZ5|ensembl:ENSP00000380969|ensembl:ENSP00000380970|ensembl:ENSP00000380971|ensembl:ENSP00000420306 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:thoc5_human(display_long)|uniprotkb:THOC5(gene name)|psi-mi:THOC5(display_short)|uniprotkb:C22orf19(gene name synonym)|uniprotkb:KIAA0983(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 79(gene name synonym)|uniprotkb:NF2/meningioma region protein pK1.3(gene name synonym)|uniprotkb:Placental protein 39.2(gene name synonym)|uniprotkb:hTREX90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_001002877.1|refseq:NP_001002878.1|refseq:NP_001002879.1|refseq:NP_003669.4|ensembl:ENSG00000100296(gene)|ensembl:ENST00000397871(transcript)|ensembl:ENST00000397872(transcript)|ensembl:ENST00000397873(transcript)|ensembl:ENST00000490103(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR019163|mint:Q13769|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:JoeUa2WhtV/dR2HSjUEBAHDZZtw9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q96FV9 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-1765605|uniprotkb:Q15219|uniprotkb:B2RBP6|uniprotkb:Q64I72|uniprotkb:Q64I73|intact:EBI-28984554|ensembl:ENSP00000261600 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:thoc1_human(display_long)|uniprotkb:hTREX84(gene name synonym)|uniprotkb:THOC1(gene name)|psi-mi:THOC1(display_short)|uniprotkb:HPR1(gene name synonym)|uniprotkb:Nuclear matrix protein p84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_005122.2|ensembl:ENSP00000261600|ensembl:ENSG00000079134(gene)|ensembl:ENST00000261600(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048297"(negative regulation of isotype switching to IgA isotypes)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR021861|mint:Q96FV9|rcsb pdb:1WXP|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:D+lk5iFzcmd1bQRa2cx/nUyq4sI9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q9Y2P8 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-11026509|uniprotkb:Q9NY00|uniprotkb:Q5VYW9|uniprotkb:Q9P044|uniprotkb:Q9H9D0|uniprotkb:D3DRI2|uniprotkb:Q5VZU1|ensembl:ENSP00000371169 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:rcl1_human(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RNAC(gene name synonym)|uniprotkb:RPC2(gene name synonym)|uniprotkb:RPCL1(gene name synonym)|uniprotkb:RTC2(gene name synonym)|uniprotkb:HSPC338(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_001273628.1|refseq:NP_001273629.1|refseq:NP_001273630.1|refseq:NP_005763.3|refseq:XP_011515975.1|ensembl:ENSG00000120158(gene)|ensembl:ENST00000381750(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|mint:Q9Y2P8|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:XP_016869665.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:8WnLDVPrx4t1eD6h+emL5waEyDY9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q13523 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q8NAV1 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-715374|uniprotkb:Q96JW1|uniprotkb:Q9BVZ8|ensembl:ENSP00000257181 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:pr38a_human(display_long)|uniprotkb:PRPF38A(gene name)|psi-mi:PRPF38A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_116253.2|ensembl:ENSG00000134748(gene)|ensembl:ENST00000257181(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005037(PRP38)|interpro:IPR024767|mint:Q8NAV1|rcsb pdb:4RZ9|rcsb pdb:4RZA|rcsb pdb:5F5S|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:Cxehw4X82E4XmwydakoLprmkgmQ9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:O43447 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-1055615|intact:EBI-6190037|uniprotkb:A6NNE7|ensembl:ENSP00000503384|ensembl:ENSP00000503489|ensembl:ENSP00000503922|ensembl:ENSP00000504108|ensembl:ENSP00000504595|ensembl:ENSP00000361630|ensembl:ENSP00000306614 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:ppih_human(display_long)|uniprotkb:U-snRNP-associated cyclophilin SnuCyp-20(gene name synonym)|uniprotkb:Small nuclear ribonucleoprotein particle-specific cyclophilin H(gene name synonym)|uniprotkb:PPIH(gene name)|psi-mi:PPIH(display_short)|uniprotkb:CYP20(gene name synonym)|uniprotkb:CYPH(gene name synonym)|uniprotkb:Rotamase H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_006338.1|refseq:XP_005270419.1|ensembl:ENST00000304979(transcript)|ensembl:ENST00000372550(transcript)|ensembl:ENST00000676675(transcript)|ensembl:ENST00000677900(transcript)|ensembl:ENST00000678038(transcript)|ensembl:ENST00000678333(transcript)|ensembl:ENST00000678803(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071001"(U4/U6 snRNP)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|mint:O43447|rcsb pdb:1MZW|rcsb pdb:1QOI|rcsb pdb:5O9Z|rcsb pdb:6AHD|reactome:R-HSA-72163|ensembl:ENSG00000171960(gene)|refseq:NP_001317439.1|refseq:XP_016855546.1|refseq:XP_016855547.1|refseq:XP_016855548.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:6gE98w/LLmT7FlCBnaBDk+GWvQU9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:P02545 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q5HYJ3 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-751192|uniprotkb:Q6PIU3|uniprotkb:Q8TC53|uniprotkb:B2R9C2|ensembl:ENSP00000351631 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:fa76b_human(display_long)|uniprotkb:FAM76B(gene name)|psi-mi:FAM76B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_653265.3|ensembl:ENSG00000077458(gene)|ensembl:ENST00000358780(transcript)|go:"GO:0016607"(nuclear speck)|interpro:IPR029661|interpro:IPR032017|mint:Q5HYJ3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:FWmHMXjKuPdNvpa793hQ1F+Tb909606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q86XP3 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q9UKF6 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q9P2I0 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-1043224|uniprotkb:Q6NSJ1|uniprotkb:Q9H3W7|ensembl:ENSP00000298875|uniprotkb:B3KME1 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:cpsf2_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:KIAA1367(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:Q9P2I0|rcsb pdb:6URG|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|ensembl:ENSG00000165934(gene)|ensembl:ENST00000298875(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016020"(membrane)|refseq:NP_059133.1|refseq:NP_001309201.1|dip:DIP-42500N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:RYiaQ8q9VM7htGre4S8PkSQaCz89606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q10570 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:O60563 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:O95817 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-747185|uniprotkb:Q3B763|uniprotkb:Q9NT20|uniprotkb:Q9P120|uniprotkb:A8K5L8|ensembl:ENSP00000358081 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:bag3_human(display_long)|uniprotkb:Bcl-2-associated athanogene 3(gene name synonym)|uniprotkb:Bcl-2-binding protein Bis(gene name synonym)|uniprotkb:Docking protein CAIR-1(gene name synonym)|uniprotkb:BAG3(gene name)|psi-mi:BAG3(display_short)|uniprotkb:BIS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_004272.2|ensembl:ENSG00000151929(gene)|ensembl:ENST00000369085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007420"(brain development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0021510"(spinal cord development)|go:"GO:0030018"(Z disc)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773|mint:O95817|reactome:R-HSA-3371453|go:"GO:0101031"(chaperone complex)|dip:DIP-41273N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:Ld26VRSMJghXG/U98A76RijSDBc9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q8N4T4 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-745468|uniprotkb:Q49AG0|uniprotkb:Q6TPQ2|uniprotkb:Q96ST6|ensembl:ENSP00000367638 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:arg39_human(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_116207.2|ensembl:ENSG00000137135(gene)|ensembl:ENST00000378387(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0030335"(positive regulation of cell migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR042987|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B2RWW0 uniprotkb:Q9ULX6 intact:EBI-25410455|ensembl:ENSMUSP00000047431|uniprotkb:Q8K2L9|uniprotkb:Q920D6 intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557 psi-mi:tagap_mouse(display_long)|uniprotkb:T-cell activation GTPase-activating protein(gene name synonym)|uniprotkb:Tagap(gene name)|psi-mi:Tagap(display_short) psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410472|imex:IM-26436-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000033450(gene)|ensembl:ENSMUST00000036370(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0051607"(defense response to virus)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|refseq:NP_666080.1 refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Mcek3jmpItrm7hj43Sbljmcg4xg10090 rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606 rigid:Qi1AsXKsNJCg8+KZU/Yx8aKlm5A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKW4-1 uniprotkb:P62987 intact:EBI-25410537 intact:EBI-357304|ensembl:ENSP00000388107|ensembl:ENSP00000396910|ensembl:ENSP00000470419|ensembl:ENSP00000470507|ensembl:ENSP00000471062|ensembl:ENSP00000471464|ensembl:ENSP00000471622|ensembl:ENSP00000472264|ensembl:ENSP00000472545|ensembl:ENSP00000473048|uniprotkb:P14793|uniprotkb:Q9BX98|uniprotkb:Q9UPK7|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8 psi-mi:q9ukw41(display_long)|uniprotkb:VAV3(gene name)|psi-mi:VAV3(display_short)|uniprotkb:Alpha(isoform synonym) psi-mi:rl40_human(display_long)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:Ubiquitin A-52 residue ribosomal protein fusion product 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410543|imex:IM-26436-98 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9UKW4-1(isoform-parent) ensembl:ENSG00000221983(gene)|ensembl:ENST00000430157(transcript)|ensembl:ENST00000442744(transcript)|ensembl:ENST00000595158(transcript)|rcsb pdb:2MBH|rcsb pdb:2MJB|rcsb pdb:2MUR|ensembl:ENST00000595683(transcript)|ensembl:ENST00000596273(transcript)|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBD|ensembl:ENST00000596304(transcript)|rcsb pdb:2NBE|rcsb pdb:2RSU|rcsb pdb:4HJK|ensembl:ENST00000597451(transcript)|ensembl:ENST00000598780(transcript)|rcsb pdb:4JIO|rcsb pdb:4P4H|rcsb pdb:4PIG|ensembl:ENST00000599551(transcript)|ensembl:ENST00000599595(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:4PIH|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017085"(response to insecticide)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|mint:P62987|rcsb pdb:2LJ5|rcsb pdb:4PIJ|rcsb pdb:4RF0|rcsb pdb:4S1Z|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XKL|rcsb pdb:5AJ0|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5HPK|rcsb pdb:5HPL|rcsb pdb:5HPS|rcsb pdb:5HPT|rcsb pdb:5J26|rcsb pdb:5J8P|rcsb pdb:5JBV|rcsb pdb:5JBY|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:4RF1|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7AY1|rcsb pdb:7BHP|rcsb pdb:7M3Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|rcsb pdb:6Z6N|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-69231|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|refseq:NP_001029102.1|refseq:NP_003324.1|refseq:NP_001307947.1|refseq:NP_001307948.1|refseq:NP_001307949.1|refseq:NP_001307946.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sCvtyb/upL3UweAEXaHjZEkKH6M9606 rogid:x9O/Pbww4D28M1+hIj+p0xrUXgU9606 rigid:rI5aS7alJ15m6amw9R8JBQ6p5WE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKW4-1 uniprotkb:Q9Y2X3 intact:EBI-25410537 intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279 psi-mi:q9ukw41(display_long)|uniprotkb:VAV3(gene name)|psi-mi:VAV3(display_short)|uniprotkb:Alpha(isoform synonym) psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410543|imex:IM-26436-98 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9UKW4-1(isoform-parent) refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sCvtyb/upL3UweAEXaHjZEkKH6M9606 rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606 rigid:rI5aS7alJ15m6amw9R8JBQ6p5WE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKW4-1 uniprotkb:P33993 intact:EBI-25410537 intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288 psi-mi:q9ukw41(display_long)|uniprotkb:VAV3(gene name)|psi-mi:VAV3(display_short)|uniprotkb:Alpha(isoform synonym) psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410543|imex:IM-26436-98 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9UKW4-1(isoform-parent) refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sCvtyb/upL3UweAEXaHjZEkKH6M9606 rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606 rigid:rI5aS7alJ15m6amw9R8JBQ6p5WE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKW4-1 uniprotkb:Q9Y383 intact:EBI-25410537 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 psi-mi:q9ukw41(display_long)|uniprotkb:VAV3(gene name)|psi-mi:VAV3(display_short)|uniprotkb:Alpha(isoform synonym) psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410543|imex:IM-26436-98 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9UKW4-1(isoform-parent) ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sCvtyb/upL3UweAEXaHjZEkKH6M9606 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rigid:rI5aS7alJ15m6amw9R8JBQ6p5WE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKW4-1 uniprotkb:Q6UN15 intact:EBI-25410537 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:q9ukw41(display_long)|uniprotkb:VAV3(gene name)|psi-mi:VAV3(display_short)|uniprotkb:Alpha(isoform synonym) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410543|imex:IM-26436-98 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9UKW4-1(isoform-parent) ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sCvtyb/upL3UweAEXaHjZEkKH6M9606 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 rigid:rI5aS7alJ15m6amw9R8JBQ6p5WE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKW4-1 uniprotkb:Q96S66 intact:EBI-25410537 intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|ensembl:ENSP00000349456|ensembl:ENSP00000358986|ensembl:ENSP00000502251|ensembl:ENSP00000502457|ensembl:ENSP00000502648|ensembl:ENSP00000502836 psi-mi:q9ukw41(display_long)|uniprotkb:VAV3(gene name)|psi-mi:VAV3(display_short)|uniprotkb:Alpha(isoform synonym) psi-mi:clcc1_human(display_long)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410543|imex:IM-26436-98 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9UKW4-1(isoform-parent) refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940(gene)|ensembl:ENST00000356970(transcript)|ensembl:ENST00000369969(transcript)|ensembl:ENST00000674849(transcript)|ensembl:ENST00000675508(transcript)|ensembl:ENST00000675654(transcript)|ensembl:ENST00000675956(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR009231(Mid-1-related chloride channel) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:sCvtyb/upL3UweAEXaHjZEkKH6M9606 rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606 rigid:rI5aS7alJ15m6amw9R8JBQ6p5WE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q17R89-1 uniprotkb:Q15642 intact:EBI-25410514|ensembl:ENSP00000368994 intact:EBI-739936|uniprotkb:O15184|uniprotkb:Q53G22|uniprotkb:Q5TZN1|uniprotkb:Q6FI24|uniprotkb:Q8NFL1|uniprotkb:Q8TCY1|uniprotkb:Q8TDX3|uniprotkb:Q96RJ1|uniprotkb:B2R8A6|uniprotkb:B7WP22|uniprotkb:D6W645|intact:EBI-28977062|ensembl:ENSP00000320117 psi-mi:q17r89-1(display_long)|uniprotkb:NPC-A-10(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)|uniprotkb:ARHGAP44(gene name)|psi-mi:ARHGAP44(display_short)|uniprotkb:KIAA0672(gene name synonym)|uniprotkb:RICH2(gene name synonym) psi-mi:cip4_human(display_long)|uniprotkb:TRIP10(gene name)|psi-mi:TRIP10(display_short)|uniprotkb:CIP4(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 10(gene name synonym)|uniprotkb:Protein Felic(gene name synonym)|uniprotkb:Salt tolerant protein(gene name synonym)|uniprotkb:STOT(gene name synonym)|uniprotkb:STP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410521|imex:IM-26436-134 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000006740(gene)|ensembl:ENST00000379672(transcript)|intact:EBI-720416(isoform-parent) ensembl:ENSP00000320117|ensembl:ENST00000313285|ensembl:ENSP00000320493|refseq:NP_004231.1|ensembl:ENSG00000125733(gene)|ensembl:ENST00000313244(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007154"(cell communication)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|interpro:IPR027267|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR028498|interpro:IPR031160|interpro:IPR036028|mint:Q15642|rcsb pdb:2CT4|rcsb pdb:2EFK|rcsb pdb:2KE4|reactome:R-HSA-8856828|reactome:R-HSA-9013406|refseq:NP_001275891.1|refseq:NP_001275892.1|dip:DIP-39840N - - crc64:A9BFE85520C7ABC5 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gN2xiWHjD8x8sIV6o2YJV+/RRSQ9606 rogid:6DvFGTlXvKhqvKlLcV1sRucCKzo9606 rigid:7CasSnX3PjlCqOuiYX3Vsomi+Q0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q17R89-1 uniprotkb:Q9Y3L3 intact:EBI-25410514|ensembl:ENSP00000368994 intact:EBI-346869|uniprotkb:Q5R3N0|uniprotkb:Q6IBZ2|uniprotkb:Q6ZVL9|uniprotkb:Q96HQ5|uniprotkb:Q9NSQ9|ensembl:ENSP00000497104 psi-mi:q17r89-1(display_long)|uniprotkb:NPC-A-10(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)|uniprotkb:ARHGAP44(gene name)|psi-mi:ARHGAP44(display_short)|uniprotkb:KIAA0672(gene name synonym)|uniprotkb:RICH2(gene name synonym) psi-mi:3bp1_human(display_long)|uniprotkb:SH3BP1(gene name)|psi-mi:SH3BP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410521|imex:IM-26436-134 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000006740(gene)|ensembl:ENST00000379672(transcript)|intact:EBI-720416(isoform-parent) refseq:NP_061830.3|ensembl:ENSG00000100092(gene)|ensembl:ENST00000649765(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|interpro:IPR000198(RhoGAP)|interpro:IPR004148(BAR)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|mint:Q9Y3L3|rcsb pdb:4J9D|rcsb pdb:4J9F|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gN2xiWHjD8x8sIV6o2YJV+/RRSQ9606 rogid:FLnCGJhsS+syrKyjVQG4Q6UcZeU9606 rigid:7CasSnX3PjlCqOuiYX3Vsomi+Q0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q17R89-1 uniprotkb:Q9Y5K6 intact:EBI-25410514|ensembl:ENSP00000368994 intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264 psi-mi:q17r89-1(display_long)|uniprotkb:NPC-A-10(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)|uniprotkb:ARHGAP44(gene name)|psi-mi:ARHGAP44(display_short)|uniprotkb:KIAA0672(gene name synonym)|uniprotkb:RICH2(gene name synonym) psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410521|imex:IM-26436-134 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000006740(gene)|ensembl:ENST00000379672(transcript)|intact:EBI-720416(isoform-parent) ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gN2xiWHjD8x8sIV6o2YJV+/RRSQ9606 rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606 rigid:7CasSnX3PjlCqOuiYX3Vsomi+Q0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q17R89-1 uniprotkb:Q68EM7 intact:EBI-25410514|ensembl:ENSP00000368994 intact:EBI-1642807|uniprotkb:A8K6M6|uniprotkb:Q6ZUS4|uniprotkb:Q7Z2F2|uniprotkb:Q8NDG2|uniprotkb:Q96KS2|uniprotkb:Q96KS3|uniprotkb:Q96SS8|uniprotkb:Q9BVF6|uniprotkb:Q9H8U5|uniprotkb:Q9NW54|intact:EBI-2398436|ensembl:ENSP00000289968|ensembl:ENSP00000500372 psi-mi:q17r89-1(display_long)|uniprotkb:NPC-A-10(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)|uniprotkb:ARHGAP44(gene name)|psi-mi:ARHGAP44(display_short)|uniprotkb:KIAA0672(gene name synonym)|uniprotkb:RICH2(gene name synonym) psi-mi:rhg17_human(display_long)|uniprotkb:ARHGAP17(gene name)|psi-mi:ARHGAP17(display_short)|uniprotkb:Rho-type GTPase-activating protein 17(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 1(gene name synonym)|uniprotkb:MSTP066(orf name)|uniprotkb:MSTP110(orf name)|uniprotkb:RICH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410521|imex:IM-26436-134 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000006740(gene)|ensembl:ENST00000379672(transcript)|intact:EBI-720416(isoform-parent) refseq:NP_001006635.1|refseq:NP_060524.4|ensembl:ENSG00000140750(gene)|ensembl:ENSG00000288353(gene)|ensembl:ENST00000289968(transcript)|ensembl:ENST00000673560(transcript)|go:"GO:0005096"(GTPase activator activity)|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013423|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035020"(regulation of Rac protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR004148(BAR)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|go:"GO:0005654"(nucleoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gN2xiWHjD8x8sIV6o2YJV+/RRSQ9606 rogid:ShqZATP0+ROgRhy0Afi5gqZ1JVY9606 rigid:7CasSnX3PjlCqOuiYX3Vsomi+Q0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q17R89-1 uniprotkb:P24752 intact:EBI-25410514|ensembl:ENSP00000368994 intact:EBI-1051459|uniprotkb:B2R6H1|uniprotkb:G3XAB4|uniprotkb:Q96FG8|ensembl:ENSP00000265838 psi-mi:q17r89-1(display_long)|uniprotkb:NPC-A-10(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)|uniprotkb:ARHGAP44(gene name)|psi-mi:ARHGAP44(display_short)|uniprotkb:KIAA0672(gene name synonym)|uniprotkb:RICH2(gene name synonym) psi-mi:thil_human(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:T2(gene name synonym)|uniprotkb:ACAT1(gene name)|psi-mi:ACAT1(display_short)|uniprotkb:ACAT(gene name synonym)|uniprotkb:MAT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410521|imex:IM-26436-134 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000006740(gene)|ensembl:ENST00000379672(transcript)|intact:EBI-720416(isoform-parent) refseq:NP_000010.1|ensembl:ENSG00000075239(gene)|ensembl:ENST00000265838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007420"(brain development)|go:"GO:0009725"(response to hormone)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016453"(C-acetyltransferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046356"(acetyl-CoA catabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072229"(metanephric proximal convoluted tubule development)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1902224"(ketone body metabolic process)|go:"GO:1902860"(propionyl-CoA biosynthetic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|rcsb pdb:2F2S|rcsb pdb:2IB7|rcsb pdb:2IB8|rcsb pdb:2IB9|rcsb pdb:2IBU|rcsb pdb:2IBW|rcsb pdb:2IBY|reactome:R-HSA-70895|reactome:R-HSA-77108|reactome:R-HSA-77111 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gN2xiWHjD8x8sIV6o2YJV+/RRSQ9606 rogid:UYAY+kDdcJqx/hrDFoXH9rgtm/E9606 rigid:7CasSnX3PjlCqOuiYX3Vsomi+Q0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:P09012 intact:EBI-25410561 intact:EBI-607085|ensembl:ENSP00000243563 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:snrpa_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|ensembl:ENSG00000077312(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034407|interpro:IPR034409|interpro:IPR035979|mint:P09012|rcsb pdb:1AUD|ensembl:ENST00000243563(transcript)|rcsb pdb:1DRZ|rcsb pdb:1DZ5|rcsb pdb:1FHT|rcsb pdb:1M5K|rcsb pdb:1M5O|rcsb pdb:1M5P|rcsb pdb:1M5V|rcsb pdb:1NU4|rcsb pdb:1OIA|rcsb pdb:1SJ3|rcsb pdb:1SJ4|rcsb pdb:1SJF|rcsb pdb:1U6B|rcsb pdb:1URN|rcsb pdb:1VBX|rcsb pdb:1VBY|rcsb pdb:1VBZ|rcsb pdb:1VC0|rcsb pdb:1VC5|rcsb pdb:1VC6|rcsb pdb:1ZZN|rcsb pdb:2A3J|rcsb pdb:2NZ4|rcsb pdb:2OIH|rcsb pdb:2OJ3|rcsb pdb:2U1A|rcsb pdb:3BO2|rcsb pdb:3BO3|rcsb pdb:3BO4|rcsb pdb:3CUL|rcsb pdb:3CUN|rcsb pdb:3EGZ|rcsb pdb:3G8S|rcsb pdb:3G8T|rcsb pdb:3G96|rcsb pdb:3G9C|rcsb pdb:3HHN|rcsb pdb:3IIN|rcsb pdb:3IRW|rcsb pdb:3IWN|rcsb pdb:3K0J|rcsb pdb:3L3C|rcsb pdb:3MUM|rcsb pdb:3MUR|rcsb pdb:3MUT|rcsb pdb:3R1H|rcsb pdb:3R1L|rcsb pdb:3UCU|rcsb pdb:3UCZ|rcsb pdb:3UD3|rcsb pdb:3UD4|rcsb pdb:3MUV|rcsb pdb:3UTR|rcsb pdb:4C4W|rcsb pdb:4PR6|rcsb pdb:4PRF|rcsb pdb:4W90|rcsb pdb:4W92|rcsb pdb:3MXH|rcsb pdb:3P49|rcsb pdb:3PGW|rcsb pdb:4YB1|rcsb pdb:5DDO|rcsb pdb:5DDP|rcsb pdb:5DDQ|rcsb pdb:5DDR|rcsb pdb:5FJ4|rcsb pdb:6LAS|rcsb pdb:6LAU|rcsb pdb:6LAX|rcsb pdb:6LAZ|rcsb pdb:6QX9|rcsb pdb:6SQN|rcsb pdb:6SQQ|rcsb pdb:6SQT|rcsb pdb:6SQV|rcsb pdb:6SR7|rcsb pdb:6XH0|rcsb pdb:6XH1|rcsb pdb:6XH2|rcsb pdb:6XH3|rcsb pdb:7AEP|rcsb pdb:7B0Y|rcsb pdb:7D7V|rcsb pdb:7LHX|reactome:R-HSA-72163|refseq:NP_004587.1|dip:DIP-29407N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:BJ9zdDzOPs9JYgU8lErj/maq0AY9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:Q6RFH5 intact:EBI-25410561 intact:EBI-722366|uniprotkb:Q9BRC9|uniprotkb:Q9H6X8|uniprotkb:Q9NVY2|uniprotkb:A8K8G5|ensembl:ENSP00000278856|ensembl:ENSP00000432119|ensembl:ENSP00000435726 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:wdr74_human(display_long)|uniprotkb:NOP seven-associated protein 1(gene name synonym)|uniprotkb:WDR74(gene name)|psi-mi:WDR74(display_short)|uniprotkb:NSA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_060563.2|refseq:XP_005274112.1|refseq:NP_001294906.1|ensembl:ENSG00000133316(gene)|ensembl:ENST00000278856(transcript)|ensembl:ENST00000525239(transcript)|ensembl:ENST00000529106(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037379|mint:Q6RFH5 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:KGh4kcZ85zi1yj6Ow10pW3h7ECM9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:P10515 intact:EBI-25410561 intact:EBI-2959723|ensembl:ENSP00000280346|uniprotkb:Q16783|uniprotkb:Q53EP3 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:odp2_human(display_long)|uniprotkb:DLAT(gene name)|psi-mi:DLAT(display_short)|uniprotkb:DLTA(gene name synonym)|uniprotkb:70 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:M2 antigen complex 70 kDa subunit(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_001922.2|ensembl:ENSG00000150768(gene)|ensembl:ENST00000280346(transcript)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P10515|rcsb pdb:1FYC|rcsb pdb:1Y8N|rcsb pdb:1Y8O|rcsb pdb:1Y8P|rcsb pdb:2DNE|rcsb pdb:2PNR|rcsb pdb:2Q8I|rcsb pdb:3B8K|rcsb pdb:3CRK|rcsb pdb:3CRL|rcsb pdb:6CT0|rcsb pdb:6H55|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268|dip:DIP-29496N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:Owh80Cm4CXvo2rPKUhLGc/U47co9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:Q00059 intact:EBI-25410561 intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:Q8NEF9 intact:EBI-25410561 intact:EBI-2824681|uniprotkb:Q5QFI2|uniprotkb:Q96AH4|uniprotkb:Q96DK2|ensembl:ENSP00000341324 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:srfb1_human(display_long)|uniprotkb:SRFBP1(gene name)|psi-mi:SRFBP1(display_short)|uniprotkb:SRF-dependent transcription regulation-associated protein(gene name synonym)|uniprotkb:p49/STRAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) ensembl:ENSG00000151304(gene)|ensembl:ENST00000339397(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR015158(Bud-site selection protein, BUD22)|interpro:IPR037393|refseq:NP_689759.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:MQv9j4+l9h+7z05X/bRJAompesc9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:P08579 intact:EBI-25410561 intact:EBI-1053651|uniprotkb:Q9UJD4|uniprotkb:B2R7J3|uniprotkb:D3DW21|ensembl:ENSP00000246071|ensembl:ENSP00000367178 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:ru2b_human(display_long)|uniprotkb:SNRPB2(gene name)|psi-mi:SNRPB2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_003083.1|refseq:NP_937863.1|ensembl:ENSG00000125870(gene)|ensembl:ENST00000246071(transcript)|ensembl:ENST00000377943(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070990"(snRNP binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034562|interpro:IPR034564|interpro:IPR035979|mint:P08579|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:AzDL3wfFG4HmOfTs8NJL6bWjgrc9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:O43660 intact:EBI-25410561 intact:EBI-1051504|uniprotkb:Q3KQY5|uniprotkb:Q8WUD8|uniprotkb:B3KMK4|ensembl:ENSP00000424417 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:plrg1_human(display_long)|uniprotkb:PLRG1(gene name)|psi-mi:PLRG1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_001188493.1|refseq:NP_002660.1|ensembl:ENSG00000171566(gene)|ensembl:ENST00000499023(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:O43660|rcsb pdb:4YVD|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DH6|rcsb pdb:7DVQ|reactome:R-HSA-72163|interpro:IPR020472 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:TdZ60+R9eEw7Q0zgsHjv8DImHMA9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:P49902 intact:EBI-25410561 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:P07196 intact:EBI-25410561 intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:Q8ND56 intact:EBI-25410561 intact:EBI-1384320|uniprotkb:Q76LX7|uniprotkb:Q96AR3|uniprotkb:Q96K73|uniprotkb:Q96SN5|uniprotkb:Q9UFR3|intact:EBI-2563702|uniprotkb:B4DTG6|ensembl:ENSP00000413964|ensembl:ENSP00000459843 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:ls14a_human(display_long)|uniprotkb:C19orf13(gene name synonym)|uniprotkb:FAM61A(gene name synonym)|uniprotkb:Protein SCD6 homolog(gene name synonym)|uniprotkb:Protein FAM61A(gene name synonym)|uniprotkb:Putative alpha-synuclein-binding protein(gene name synonym)|uniprotkb:LSM14A(gene name)|psi-mi:LSM14A(display_short)|uniprotkb:RAP55(gene name synonym)|uniprotkb:RAP55A(gene name synonym)|uniprotkb:RNA-associated protein 55A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_001107565.1|refseq:NP_056393.2|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:Q8ND56|rcsb pdb:6F9W|ensembl:ENSG00000257103(gene)|ensembl:ENSG00000262860(gene)|ensembl:ENST00000433627(transcript)|ensembl:ENST00000570462(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:YW/zx4XyhcZZr3WCZIr1OVpyakA9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:O15397 intact:EBI-25410561 intact:EBI-358808|intact:EBI-28976929|ensembl:ENSP00000256079|uniprotkb:B7Z7M3 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:ipo8_human(display_long)|uniprotkb:IPO8(gene name)|psi-mi:IPO8(display_short)|uniprotkb:RANBP8(gene name synonym)|uniprotkb:Ran-binding protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_006381.2|ensembl:ENSP00000256079|ensembl:ENST00000544829|ensembl:ENSP00000444520|ensembl:ENSG00000133704(gene)|ensembl:ENST00000256079(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O15397|reactome:R-HSA-5578749|refseq:NP_001177924.1|dip:DIP-44186N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:cKZQfshtWCcKP/0VfuW5CMi1YbQ9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:Q16352 intact:EBI-25410561 intact:EBI-366258|uniprotkb:Q9BRC5|uniprotkb:B1AQK0|ensembl:ENSP00000358865 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:ainx_human(display_long)|uniprotkb:INA(gene name)|psi-mi:INA(display_short)|uniprotkb:66 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 5(gene name synonym)|uniprotkb:NEF5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_116116.1|ensembl:ENSG00000148798(gene)|ensembl:ENST00000369849(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005883"(neurofilament)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027703|interpro:IPR039008|mint:Q16352 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:HXC2d0wajSa0s9r7b4qtpqi3g+s9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:Q5SSJ5 intact:EBI-25410561 intact:EBI-2880687|ensembl:ENSP00000312625|ensembl:ENSP00000403039|uniprotkb:Q5SWC6|uniprotkb:Q6PIM9|uniprotkb:B3KMZ8|uniprotkb:A8K5D7|uniprotkb:Q8NDF0|uniprotkb:Q05BI0|uniprotkb:B4E210|uniprotkb:A6NI71|uniprotkb:Q9UHY0|uniprotkb:Q5SSJ6 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:hp1b3_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short)|uniprotkb:Protein HP1-BP74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) ensembl:ENSG00000127483(gene)|ensembl:ENST00000312239(transcript)|ensembl:ENST00000438032(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|mint:Q5SSJ5|rcsb pdb:2RQP|go:"GO:0005694"(chromosome)|refseq:XP_016856882.1|refseq:XP_016856883.1|refseq:XP_011539834.1|refseq:XP_011539835.1|refseq:XP_011539836.1|refseq:NP_057371.2|refseq:XP_005245932.1|refseq:XP_005245933.1|refseq:XP_005245934.1|refseq:XP_005245935.1|refseq:XP_005245936.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:kLFithZZv+Qn9YLElEnX81awKDw9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:P15170 intact:EBI-25410561 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:Q53R41 intact:EBI-25410561 intact:EBI-3957005|uniprotkb:Q8N583|uniprotkb:Q8TEA9|uniprotkb:Q96JM5|uniprotkb:Q96N71|uniprotkb:Q9H6T4|ensembl:ENSP00000400513 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:fakd1_human(display_long)|uniprotkb:FASTKD1(gene name)|psi-mi:FASTKD1(display_short)|uniprotkb:KIAA1800(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_078898.3|refseq:NP_001268405.1|refseq:NP_001308975.1|refseq:NP_001308977.1|refseq:NP_001308978.1|refseq:XP_016860400.1|ensembl:ENSG00000138399(gene)|ensembl:ENST00000453153(transcript)|go:"GO:0000959"(mitochondrial RNA metabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:eizlBY2w9CXu4y4WE8R4QOUWoXA9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:P35221 intact:EBI-25410561 intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P227-1 uniprotkb:P25311 intact:EBI-25410561 intact:EBI-2513837|ensembl:ENSP00000292401|uniprotkb:Q5XKQ4|uniprotkb:O60386|uniprotkb:Q8N4N0|uniprotkb:D6W5T8 psi-mi:q9p2271(display_long)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:za2g_human(display_long)|uniprotkb:AZGP1(gene name)|psi-mi:AZGP1(display_short)|uniprotkb:ZAG(gene name synonym)|uniprotkb:ZNGP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410568|imex:IM-26436-220 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P227-1(isoform-parent) ensembl:ENSG00000160862(gene)|ensembl:ENST00000292401(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|interpro:IPR036179|interpro:IPR037055|mint:P25311|rcsb pdb:1T7V|rcsb pdb:1T7W|rcsb pdb:1T7X|rcsb pdb:1T7Y|rcsb pdb:1T7Z|rcsb pdb:1T80|rcsb pdb:1ZAG|rcsb pdb:3ES6|rcsb pdb:6R2U|reactome:R-HSA-5223345|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001176.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rogid:3Fp6qALNiZRqsI8Kh2lTQ9IMYek9606 rigid:Rwkz9zWp/wjZUkl72VIHRTQaeD4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NI28 uniprotkb:Q8N5G2 intact:EBI-21517923|ensembl:ENSP00000298815|uniprotkb:Q96M56 intact:EBI-2683507|uniprotkb:Q2TLX5|uniprotkb:Q2TLX6|uniprotkb:B1AK00|uniprotkb:Q9NVG6|ensembl:ENSP00000363463 psi-mi:rhg42_human(display_long)|uniprotkb:ARHGAP42(gene name)|psi-mi:ARHGAP42(display_short)|uniprotkb:GRAF3(gene name synonym)|uniprotkb:TMEM133(gene name synonym)|uniprotkb:Rho GTPase-activating protein 10-like(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 42(gene name synonym) psi-mi:macoi_human(display_long)|uniprotkb:Transmembrane protein 57(gene name synonym)|uniprotkb:MACO1(gene name)|psi-mi:MACO1(display_short)|uniprotkb:TMEM57(gene name synonym)|uniprotkb:Macoilin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410626|imex:IM-26436-136 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165895(gene)|ensembl:ENST00000298815(transcript)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR036028|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|refseq:NP_689645.2 refseq:NP_001269493.1|refseq:NP_060672.2|ensembl:ENSG00000204178(gene)|ensembl:ENST00000374343(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030424"(axon)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|interpro:IPR019130|reactome:R-HSA-8980692|reactome:R-HSA-9013106 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:j2Na/wwSDUhSIpBFMOojVVnzkKQ9606 rogid:k8wUq+ZSQRPwhRdj2c8pgzgQEgU9606 rigid:tKVHwGJrCwcTkWGyDJRRgyQxzcs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NI28 uniprotkb:P35659 intact:EBI-21517923|ensembl:ENSP00000298815|uniprotkb:Q96M56 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:rhg42_human(display_long)|uniprotkb:ARHGAP42(gene name)|psi-mi:ARHGAP42(display_short)|uniprotkb:GRAF3(gene name synonym)|uniprotkb:TMEM133(gene name synonym)|uniprotkb:Rho GTPase-activating protein 10-like(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 42(gene name synonym) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410626|imex:IM-26436-136 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165895(gene)|ensembl:ENST00000298815(transcript)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR036028|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|refseq:NP_689645.2 ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:j2Na/wwSDUhSIpBFMOojVVnzkKQ9606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 rigid:tKVHwGJrCwcTkWGyDJRRgyQxzcs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NI28 uniprotkb:P05090 intact:EBI-21517923|ensembl:ENSP00000298815|uniprotkb:Q96M56 intact:EBI-715495|uniprotkb:Q6IBG6|uniprotkb:B2R579|uniprotkb:D3DNW6|ensembl:ENSP00000345179 psi-mi:rhg42_human(display_long)|uniprotkb:ARHGAP42(gene name)|psi-mi:ARHGAP42(display_short)|uniprotkb:GRAF3(gene name synonym)|uniprotkb:TMEM133(gene name synonym)|uniprotkb:Rho GTPase-activating protein 10-like(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 42(gene name synonym) psi-mi:apod_human(display_long)|uniprotkb:APOD(gene name)|psi-mi:APOD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410626|imex:IM-26436-136 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165895(gene)|ensembl:ENST00000298815(transcript)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR036028|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|refseq:NP_689645.2 refseq:NP_001638.1|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048678"(response to axon injury)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060588"(negative regulation of lipoprotein lipid oxidation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002969(Apolipoprotein D)|interpro:IPR012674(Calycin)|interpro:IPR022271|interpro:IPR022272|interpro:IPR026222|mint:P05090|rcsb pdb:2APD|rcsb pdb:2HZQ|rcsb pdb:2HZR|reactome:R-HSA-804914|reactome:R-HSA-9029569|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|ensembl:ENSG00000189058(gene)|ensembl:ENST00000343267(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:j2Na/wwSDUhSIpBFMOojVVnzkKQ9606 rogid:eD7+u5/ZQ5vntlwrq6itkhCxZJU9606 rigid:tKVHwGJrCwcTkWGyDJRRgyQxzcs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DR7 uniprotkb:Q9Y383 intact:EBI-4402573|uniprotkb:Q68CL1|uniprotkb:Q6AZ96|uniprotkb:Q9H9R2|uniprotkb:Q6Q8Q8|uniprotkb:Q96AW8|uniprotkb:Q96DR6|uniprotkb:Q9H9D7|uniprotkb:Q9UFW5|uniprotkb:B3KVP8|uniprotkb:E9PBD0|ensembl:ENSP00000348828|ensembl:ENSP00000423418|ensembl:ENSP00000481927|ensembl:ENSP00000484367 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 psi-mi:arhgq_human(display_long)|uniprotkb:ARHGEF26(gene name)|psi-mi:ARHGEF26(display_short)|uniprotkb:SGEF(gene name synonym)|uniprotkb:SH3 domain-containing guanine exchange factor(gene name synonym)|uniprotkb:HMFN1864(orf name) psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410608|imex:IM-26436-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056410.3|refseq:NP_001238891.1|refseq:NP_001238892.1|ensembl:ENSG00000114790(gene)|ensembl:ENSG00000277101(gene)|go:"GO:0097178"(ruffle assembly)|ensembl:ENST00000356448(transcript)|ensembl:ENST00000465093(transcript)|ensembl:ENST00000614308(transcript)|ensembl:ENST00000618535(transcript)|interpro:IPR000219("Dbl homology (DH) domain")|go:"GO:0001726"(ruffle)|go:"GO:0001886"(endothelial cell morphogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|rcsb pdb:6MYE|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408 ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:ZyCd3KE3VzR/ZBbIdT17YnldfyY9606 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rigid:9hpjwASbPnXaZvwztAf9rqxKics false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DR7 uniprotkb:Q14160 intact:EBI-4402573|uniprotkb:Q68CL1|uniprotkb:Q6AZ96|uniprotkb:Q9H9R2|uniprotkb:Q6Q8Q8|uniprotkb:Q96AW8|uniprotkb:Q96DR6|uniprotkb:Q9H9D7|uniprotkb:Q9UFW5|uniprotkb:B3KVP8|uniprotkb:E9PBD0|ensembl:ENSP00000348828|ensembl:ENSP00000423418|ensembl:ENSP00000481927|ensembl:ENSP00000484367 intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:arhgq_human(display_long)|uniprotkb:ARHGEF26(gene name)|psi-mi:ARHGEF26(display_short)|uniprotkb:SGEF(gene name synonym)|uniprotkb:SH3 domain-containing guanine exchange factor(gene name synonym)|uniprotkb:HMFN1864(orf name) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410608|imex:IM-26436-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056410.3|refseq:NP_001238891.1|refseq:NP_001238892.1|ensembl:ENSG00000114790(gene)|ensembl:ENSG00000277101(gene)|go:"GO:0097178"(ruffle assembly)|ensembl:ENST00000356448(transcript)|ensembl:ENST00000465093(transcript)|ensembl:ENST00000614308(transcript)|ensembl:ENST00000618535(transcript)|interpro:IPR000219("Dbl homology (DH) domain")|go:"GO:0001726"(ruffle)|go:"GO:0001886"(endothelial cell morphogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|rcsb pdb:6MYE|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408 refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:ZyCd3KE3VzR/ZBbIdT17YnldfyY9606 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:9hpjwASbPnXaZvwztAf9rqxKics false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DR7 uniprotkb:P28482 intact:EBI-4402573|uniprotkb:Q68CL1|uniprotkb:Q6AZ96|uniprotkb:Q9H9R2|uniprotkb:Q6Q8Q8|uniprotkb:Q96AW8|uniprotkb:Q96DR6|uniprotkb:Q9H9D7|uniprotkb:Q9UFW5|uniprotkb:B3KVP8|uniprotkb:E9PBD0|ensembl:ENSP00000348828|ensembl:ENSP00000423418|ensembl:ENSP00000481927|ensembl:ENSP00000484367 intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64 psi-mi:arhgq_human(display_long)|uniprotkb:ARHGEF26(gene name)|psi-mi:ARHGEF26(display_short)|uniprotkb:SGEF(gene name synonym)|uniprotkb:SH3 domain-containing guanine exchange factor(gene name synonym)|uniprotkb:HMFN1864(orf name) psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410608|imex:IM-26436-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056410.3|refseq:NP_001238891.1|refseq:NP_001238892.1|ensembl:ENSG00000114790(gene)|ensembl:ENSG00000277101(gene)|go:"GO:0097178"(ruffle assembly)|ensembl:ENST00000356448(transcript)|ensembl:ENST00000465093(transcript)|ensembl:ENST00000614308(transcript)|ensembl:ENST00000618535(transcript)|interpro:IPR000219("Dbl homology (DH) domain")|go:"GO:0001726"(ruffle)|go:"GO:0001886"(endothelial cell morphogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|rcsb pdb:6MYE|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408 reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:ZyCd3KE3VzR/ZBbIdT17YnldfyY9606 rogid:odzhd70I/8uWedx0+gF38lhe60I9606 rigid:9hpjwASbPnXaZvwztAf9rqxKics false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DR7 uniprotkb:Q12959 intact:EBI-4402573|uniprotkb:Q68CL1|uniprotkb:Q6AZ96|uniprotkb:Q9H9R2|uniprotkb:Q6Q8Q8|uniprotkb:Q96AW8|uniprotkb:Q96DR6|uniprotkb:Q9H9D7|uniprotkb:Q9UFW5|uniprotkb:B3KVP8|uniprotkb:E9PBD0|ensembl:ENSP00000348828|ensembl:ENSP00000423418|ensembl:ENSP00000481927|ensembl:ENSP00000484367 intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21 psi-mi:arhgq_human(display_long)|uniprotkb:ARHGEF26(gene name)|psi-mi:ARHGEF26(display_short)|uniprotkb:SGEF(gene name synonym)|uniprotkb:SH3 domain-containing guanine exchange factor(gene name synonym)|uniprotkb:HMFN1864(orf name) psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410608|imex:IM-26436-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056410.3|refseq:NP_001238891.1|refseq:NP_001238892.1|ensembl:ENSG00000114790(gene)|ensembl:ENSG00000277101(gene)|go:"GO:0097178"(ruffle assembly)|ensembl:ENST00000356448(transcript)|ensembl:ENST00000465093(transcript)|ensembl:ENST00000614308(transcript)|ensembl:ENST00000618535(transcript)|interpro:IPR000219("Dbl homology (DH) domain")|go:"GO:0001726"(ruffle)|go:"GO:0001886"(endothelial cell morphogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|rcsb pdb:6MYE|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408 reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:ZyCd3KE3VzR/ZBbIdT17YnldfyY9606 rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606 rigid:9hpjwASbPnXaZvwztAf9rqxKics false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DR7 uniprotkb:P35659 intact:EBI-4402573|uniprotkb:Q68CL1|uniprotkb:Q6AZ96|uniprotkb:Q9H9R2|uniprotkb:Q6Q8Q8|uniprotkb:Q96AW8|uniprotkb:Q96DR6|uniprotkb:Q9H9D7|uniprotkb:Q9UFW5|uniprotkb:B3KVP8|uniprotkb:E9PBD0|ensembl:ENSP00000348828|ensembl:ENSP00000423418|ensembl:ENSP00000481927|ensembl:ENSP00000484367 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:arhgq_human(display_long)|uniprotkb:ARHGEF26(gene name)|psi-mi:ARHGEF26(display_short)|uniprotkb:SGEF(gene name synonym)|uniprotkb:SH3 domain-containing guanine exchange factor(gene name synonym)|uniprotkb:HMFN1864(orf name) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410608|imex:IM-26436-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056410.3|refseq:NP_001238891.1|refseq:NP_001238892.1|ensembl:ENSG00000114790(gene)|ensembl:ENSG00000277101(gene)|go:"GO:0097178"(ruffle assembly)|ensembl:ENST00000356448(transcript)|ensembl:ENST00000465093(transcript)|ensembl:ENST00000614308(transcript)|ensembl:ENST00000618535(transcript)|interpro:IPR000219("Dbl homology (DH) domain")|go:"GO:0001726"(ruffle)|go:"GO:0001886"(endothelial cell morphogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|rcsb pdb:6MYE|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408 ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:ZyCd3KE3VzR/ZBbIdT17YnldfyY9606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 rigid:9hpjwASbPnXaZvwztAf9rqxKics false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DR7 uniprotkb:O14936 intact:EBI-4402573|uniprotkb:Q68CL1|uniprotkb:Q6AZ96|uniprotkb:Q9H9R2|uniprotkb:Q6Q8Q8|uniprotkb:Q96AW8|uniprotkb:Q96DR6|uniprotkb:Q9H9D7|uniprotkb:Q9UFW5|uniprotkb:B3KVP8|uniprotkb:E9PBD0|ensembl:ENSP00000348828|ensembl:ENSP00000423418|ensembl:ENSP00000481927|ensembl:ENSP00000484367 intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405 psi-mi:arhgq_human(display_long)|uniprotkb:ARHGEF26(gene name)|psi-mi:ARHGEF26(display_short)|uniprotkb:SGEF(gene name synonym)|uniprotkb:SH3 domain-containing guanine exchange factor(gene name synonym)|uniprotkb:HMFN1864(orf name) psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410608|imex:IM-26436-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056410.3|refseq:NP_001238891.1|refseq:NP_001238892.1|ensembl:ENSG00000114790(gene)|ensembl:ENSG00000277101(gene)|go:"GO:0097178"(ruffle assembly)|ensembl:ENST00000356448(transcript)|ensembl:ENST00000465093(transcript)|ensembl:ENST00000614308(transcript)|ensembl:ENST00000618535(transcript)|interpro:IPR000219("Dbl homology (DH) domain")|go:"GO:0001726"(ruffle)|go:"GO:0001886"(endothelial cell morphogenesis)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|rcsb pdb:6MYE|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408 refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|ensembl:ENSG00000147044(gene)|ensembl:ENST00000378163(transcript)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:ZyCd3KE3VzR/ZBbIdT17YnldfyY9606 rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606 rigid:9hpjwASbPnXaZvwztAf9rqxKics false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:P62306 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:O96008 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:Q9NS69 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-1047508|intact:EBI-1180569|ensembl:ENSP00000216034 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:tom22_human(display_long)|uniprotkb:TOMM22(gene name)|psi-mi:TOMM22(display_short)|uniprotkb:TOM22(gene name synonym)|uniprotkb:Translocase of outer membrane 22 kDa subunit homolog(gene name synonym)|uniprotkb:1C9-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) refseq:NP_064628.1|ensembl:ENSG00000100216(gene)|ensembl:ENST00000216034(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|mint:Q9NS69|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:DI3BGFSB04B1/mMHJsBpOsCxrYk9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:Q9UMX1 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-740595|uniprotkb:Q7LCP7|uniprotkb:Q9NT90|uniprotkb:Q9NZ07|uniprotkb:Q9UHK2|uniprotkb:Q9UHM8|uniprotkb:Q9UMY0|intact:EBI-28969623|ensembl:ENSP00000358918 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:sufu_human(display_long)|uniprotkb:SUFU(gene name)|psi-mi:SUFU(display_short)|uniprotkb:UNQ650/PRO1280(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) refseq:NP_001171604.1|refseq:NP_057253.2|ensembl:ENST00000369899|ensembl:ENSP00000358915|ensembl:ENSP00000358918|ensembl:ENSP00000411597|ensembl:ENST00000423559|ensembl:ENSG00000107882(gene)|ensembl:ENST00000369902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043588"(skin development)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR037181|interpro:IPR024314|interpro:IPR038489|rcsb pdb:1M1L|rcsb pdb:4BL8|rcsb pdb:4BL9|rcsb pdb:4BLA|rcsb pdb:4BLB|rcsb pdb:4BLD|rcsb pdb:4KM8|rcsb pdb:4KM9|rcsb pdb:4KMD|rcsb pdb:4KMH|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:fY3B2k7IsBmMcCaDhHXbPsxjzYc9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:Q9UJZ1 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-1044428|ensembl:ENSP00000348886|uniprotkb:O60376|uniprotkb:Q53G29|uniprotkb:Q96FY2|uniprotkb:Q9P042|uniprotkb:D3DRN3|uniprotkb:B4E1K7 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:stml2_human(display_long)|uniprotkb:EPB72-like protein 2(gene name synonym)|uniprotkb:STOML2(gene name)|psi-mi:STOML2(display_short)|uniprotkb:SLP2(gene name synonym)|uniprotkb:HSPC108(orf name)|uniprotkb:Paraprotein target 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) ensembl:ENSG00000165283(gene)|ensembl:ENST00000356493(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q9UJZ1|reactome:R-HSA-8949664|refseq:NP_001273960.1|refseq:NP_038470.1|refseq:NP_001273961.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:VH6uT4ShPg3IpPHbQtaSVXjZAYg9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:Q16637 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:Q8TAQ2 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:Q9GZT3 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-1050793|uniprotkb:J3KMY7|ensembl:ENSP00000450909|intact:EBI-10967524 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:slirp_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)|uniprotkb:C14orf156(gene name synonym)|uniprotkb:DC23(orf name)|uniprotkb:DC50(orf name)|uniprotkb:PD04872(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) refseq:NP_112487.1|refseq:NP_001254792.1|refseq:NP_001254793.1|ensembl:ENSG00000119705(gene)|ensembl:ENST00000557342(transcript)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|mint:Q9GZT3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:8sPWOtmxPTOVlthXwBiIIp/+6go9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:P04843 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRR9 uniprotkb:Q99714 intact:EBI-750254|uniprotkb:E9PDX9|uniprotkb:Q8NAF3|uniprotkb:Q8TCJ3|uniprotkb:Q8WYR0|uniprotkb:Q96EZ2|uniprotkb:Q96S74|uniprotkb:B4DVI3|intact:EBI-28982582|ensembl:ENSP00000377386 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 psi-mi:rhg09_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 9(gene name synonym)|uniprotkb:ARHGAP9(gene name)|psi-mi:ARHGAP9(display_short) psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410638|imex:IM-26436-222 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073625.1|refseq:NP_001073626.1|refseq:NP_115885.2|refseq:XP_011536958.1|refseq:XP_011536961.1|ensembl:ENST00000393791|ensembl:ENSP00000377380|ensembl:ENSP00000377386|ensembl:ENST00000424809|ensembl:ENSP00000394307|ensembl:ENST00000430041|ensembl:ENSP00000397950|refseq:NP_001306779.1|refseq:NP_001306780.1|refseq:NP_001306781.1|refseq:XP_005269140.1|refseq:XP_016875289.1|refseq:XP_016875290.1|ensembl:ENSG00000123329(gene)|ensembl:ENST00000393797(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035465|interpro:IPR036020|interpro:IPR036028|rcsb pdb:2P0D|rcsb pdb:2P0F|rcsb pdb:2P0H|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|interpro:IPR001452(Src homology-3) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xMZoj/BPtfx1PnMPt4XsjXbGv1k9606 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rigid:r6qR4tPg/MliK67ZlTJNDjJlJrg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q8IY67 intact:EBI-25410664 intact:EBI-2105155|uniprotkb:A6NMU4|uniprotkb:Q8IY60|uniprotkb:Q8TF24|intact:EBI-2562007|ensembl:ENSP00000479520 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:ravr1_human(display_long)|uniprotkb:RAVER1(gene name)|psi-mi:RAVER1(display_short)|uniprotkb:KIAA1978(gene name synonym)|uniprotkb:Protein raver-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_597709.2|dip:DIP-46973N|ensembl:ENSG00000161847(gene)|ensembl:ENST00000615032(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034633|interpro:IPR034635|interpro:IPR035979|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3SMZ|rcsb pdb:3VF0 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:bu5ZIcFaIb6EihZAWpUflnrWL1w9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P17612 intact:EBI-25410664 intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9UQ80 intact:EBI-25410664 intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q7Z6Z7 intact:EBI-25410664 intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q6UWP8 intact:EBI-25410664 intact:EBI-11024569|uniprotkb:E9PBV3|uniprotkb:A8K5J0|ensembl:ENSP00000430242 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:sbsn_human(display_long)|uniprotkb:SBSN(gene name)|psi-mi:SBSN(display_short)|uniprotkb:UNQ698/PRO1343(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001159506.1|refseq:NP_001159507.1|refseq:NP_940940.1|ensembl:ENSG00000189001(gene)|ensembl:ENST00000452271(transcript)|go:"GO:0070062"(extracellular exosome) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:odagYPEdS9Vav1RDWyUv1l+lQA49606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P04843 intact:EBI-25410664 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O43660 intact:EBI-25410664 intact:EBI-1051504|uniprotkb:Q3KQY5|uniprotkb:Q8WUD8|uniprotkb:B3KMK4|ensembl:ENSP00000424417 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:plrg1_human(display_long)|uniprotkb:PLRG1(gene name)|psi-mi:PLRG1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001188493.1|refseq:NP_002660.1|ensembl:ENSG00000171566(gene)|ensembl:ENST00000499023(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:O43660|rcsb pdb:4YVD|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DH6|rcsb pdb:7DVQ|reactome:R-HSA-72163|interpro:IPR020472 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:TdZ60+R9eEw7Q0zgsHjv8DImHMA9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P52292 intact:EBI-25410664 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q16531 intact:EBI-25410664 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9H0D6 intact:EBI-25410664 intact:EBI-372110|uniprotkb:Q3L8N4|uniprotkb:Q6KGZ9|uniprotkb:Q9BQL1|uniprotkb:Q9NTW0|uniprotkb:Q9NXS6|uniprotkb:Q9UL53|ensembl:ENSP00000366396 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:xrn2_human(display_long)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short)|uniprotkb:DHM1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_036387.2|refseq:NP_001304889.1|ensembl:ENSG00000088930(gene)|ensembl:ENST00000377191(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|mint:Q9H0D6|reactome:R-HSA-390471|reactome:R-HSA-6791226|dip:DIP-31166N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:Ui0NiU+fGe68hK5CYTolkhioQbQ9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q53GS9 intact:EBI-25410664 intact:EBI-1044822|uniprotkb:Q6NX47|uniprotkb:Q96RK9|uniprotkb:Q9BV89|uniprotkb:Q9H381|uniprotkb:Q9P050|uniprotkb:Q9Y310|uniprotkb:A8K086|ensembl:ENSP00000312981|ensembl:ENSP00000386864|uniprotkb:D6W5L4|intact:EBI-2557627|uniprotkb:B4DHT4|uniprotkb:B3KM40|uniprotkb:G5E9H0 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:snut2_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 65 kDa protein(gene name synonym)|uniprotkb:Inactive ubiquitin-specific peptidase 39(gene name synonym)|uniprotkb:SAD1 homolog(gene name synonym)|uniprotkb:USP39(gene name)|psi-mi:USP39(display_short)|uniprotkb:CGI-21(orf name)|uniprotkb:HSPC332(orf name)|uniprotkb:PRO2855(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_006581.2|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051301"(cell division)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR028889|interpro:IPR033809|interpro:IPR038765|go:"GO:0007049"(cell cycle)|rcsb pdb:3JCR|rcsb pdb:6AH0|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|ensembl:ENSG00000168883(gene)|ensembl:ENST00000323701(transcript)|ensembl:ENST00000409470(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|refseq:NP_001243656.1|refseq:NP_001243657.1|refseq:NP_001243654.1|refseq:NP_001243655.1|refseq:XP_006711985.1|refseq:XP_006711986.1|refseq:XP_011530789.1|refseq:XP_011530790.1|refseq:XP_016858671.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:AMLhskNenuv+zqXSa7VesSbbVK89606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9Y4E8 intact:EBI-25410664 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P26368 intact:EBI-25410664 intact:EBI-742339|uniprotkb:Q96HC5|intact:EBI-946034|ensembl:ENSP00000307863 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:u2af2_human(display_long)|uniprotkb:U2AF2(gene name)|psi-mi:U2AF2(display_short)|uniprotkb:U2AF65(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) go:"GO:0005634"(nucleus)|refseq:NP_001012496.1|refseq:NP_009210.1|ensembl:ENSG00000063244(gene)|ensembl:ENST00000308924(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|rcsb pdb:2HZC|rcsb pdb:2M0G|rcsb pdb:2U2F|rcsb pdb:2YH0|rcsb pdb:2YH1|rcsb pdb:3VAF|rcsb pdb:3VAG|rcsb pdb:3VAH|rcsb pdb:3VAI|rcsb pdb:3VAJ|rcsb pdb:3VAK|rcsb pdb:3VAL|rcsb pdb:3VAM|rcsb pdb:4FXW|rcsb pdb:4TU7|rcsb pdb:4TU8|rcsb pdb:4TU9|rcsb pdb:5EV1|rcsb pdb:5EV2|rcsb pdb:5EV3|rcsb pdb:5EV4|rcsb pdb:5W0G|rcsb pdb:5W0H|rcsb pdb:6TR0|rcsb pdb:6XLV|rcsb pdb:6XLW|rcsb pdb:6XLX|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:2G4B|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26368|rcsb pdb:1JMT|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:1U2F|go:"GO:0005654"(nucleoplasm)|dip:DIP-2154N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:HBYwOej94CoGGN7vPbk0AnbO61Q9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9H3N1 intact:EBI-25410664 intact:EBI-1051115|uniprotkb:Q8N487|uniprotkb:Q8NBN5|uniprotkb:Q9Y4T6|uniprotkb:B2R7A4|ensembl:ENSP00000393316 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:tmx1_human(display_long)|uniprotkb:Transmembrane Trx-related protein(gene name synonym)|uniprotkb:TMX1(gene name)|psi-mi:TMX1(display_short)|uniprotkb:TXNDC1(gene name synonym)|uniprotkb:TMX(gene name synonym)|uniprotkb:TXNDC(gene name synonym)|uniprotkb:PSEC0085(orf name)|uniprotkb:UNQ235/PRO268(orf name)|uniprotkb:Thioredoxin domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_110382.3|ensembl:ENSG00000139921(gene)|ensembl:ENST00000457354(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:Q9H3N1|rcsb pdb:1X5E - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:ZJH5N22Dnrk+SXa3Ysqqfu1md/I9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P27105 intact:EBI-25410664 intact:EBI-1211440|uniprotkb:Q14087|uniprotkb:Q15609|uniprotkb:Q5VX96|uniprotkb:Q96FK4|uniprotkb:B1AM77|ensembl:ENSP00000286713 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:stom_human(display_long)|uniprotkb:STOM(gene name)|psi-mi:STOM(display_short)|uniprotkb:BND7(gene name synonym)|uniprotkb:EPB72(gene name synonym)|uniprotkb:Protein 7.2b(gene name synonym)|uniprotkb:Erythrocyte band 7 integral membrane protein(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 7.2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_004090.4|refseq:NP_937837.1|ensembl:ENSG00000148175(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|ensembl:ENST00000286713(transcript)|go:"GO:0016020"(membrane)|go:"GO:0031982"(vesicle)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0072562"(blood microparticle)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901585"(regulation of acid-sensing ion channel activity)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR018080|interpro:IPR028515|interpro:IPR036013|interpro:IPR043202|mint:P27105|reactome:R-HSA-2672351|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:vN/5Kc8T+vO90Hk4N3RHD/u0pWc9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O60232 intact:EBI-25410664 intact:EBI-741415|ensembl:ENSP00000312318 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:znrd2_human(display_long)|uniprotkb:ZNRD2(gene name)|psi-mi:ZNRD2(display_short)|uniprotkb:Autoantigen p27(gene name synonym)|uniprotkb:SSSCA1(gene name synonym)|uniprotkb:Sjoegren syndrome/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_006387.1|ensembl:ENSG00000173465(gene)|ensembl:ENST00000309328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0051301"(cell division)|interpro:IPR009563(Sjogrens syndrome scleroderma autoantigen 1)|rcsb pdb:6HCZ - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:Uou80pZneoL39/0YYzb1TAbiB2I9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P05455 intact:EBI-25410664 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9Y5M8 intact:EBI-25410664 intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401|ensembl:ENSP00000503923 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_067026.3|ensembl:ENSG00000144867(gene)|ensembl:ENST00000466490(transcript)|ensembl:ENST00000678299(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9GZT3 intact:EBI-25410664 intact:EBI-1050793|uniprotkb:J3KMY7|ensembl:ENSP00000450909|intact:EBI-10967524 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:slirp_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)|uniprotkb:C14orf156(gene name synonym)|uniprotkb:DC23(orf name)|uniprotkb:DC50(orf name)|uniprotkb:PD04872(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_112487.1|refseq:NP_001254792.1|refseq:NP_001254793.1|ensembl:ENSG00000119705(gene)|ensembl:ENST00000557342(transcript)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|mint:Q9GZT3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:8sPWOtmxPTOVlthXwBiIIp/+6go9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P34897 intact:EBI-25410664 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9HCN8 intact:EBI-25410664 intact:EBI-2339921|uniprotkb:Q9BRI5|uniprotkb:A2RUD3|ensembl:ENSP00000248958 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:sdf2l_human(display_long)|uniprotkb:SDF2L1(gene name)|psi-mi:SDF2L1(display_short)|uniprotkb:PWP1-interacting protein 8(gene name synonym)|uniprotkb:UNQ1941/PRO4424(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_071327.2|ensembl:ENSG00000128228(gene)|ensembl:ENST00000248958(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0101031"(chaperone complex)|interpro:IPR016093(MIR motif)|interpro:IPR036300|mint:Q9HCN8 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:0vAPKCqCGpCARkmy7ZsTccxScgk9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P31151 intact:EBI-25410664 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q6P5R6 intact:EBI-25410664 intact:EBI-2512545|ensembl:ENSP00000346080|uniprotkb:Q32Q77 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:rl22l_human(display_long)|uniprotkb:RPL22L1(gene name)|psi-mi:RPL22L1(display_short)|uniprotkb:Large ribosomal subunit protein eL22-like 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000163584(gene)|ensembl:ENST00000295830(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR028370|interpro:IPR038526|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001093115.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:F0hKX3isBeCP4gGQNBrar7f5YUw9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O43395 intact:EBI-25410664 intact:EBI-744322|uniprotkb:O43446|uniprotkb:Q5VT54|uniprotkb:B4DSY9|intact:EBI-28983618|ensembl:ENSP00000315379 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:prpf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)|uniprotkb:U4/U6 snRNP 90 kDa protein(gene name synonym)|uniprotkb:PRPF3(gene name)|psi-mi:PRPF3(display_short)|uniprotkb:HPRP3(gene name synonym)|uniprotkb:PRP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_004689.1|ensembl:ENSP00000315379|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|interpro:IPR036483|mint:O43395|rcsb pdb:1X4Q|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|ensembl:ENSG00000117360(gene)|ensembl:ENST00000324862(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-34508N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:Y2aO1gQjTU8JERVtrLpgbXq7nLU9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O94903 intact:EBI-25410664 intact:EBI-2860631|uniprotkb:Q6FI94|ensembl:ENSP00000333551 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:plphp_human(display_long)|uniprotkb:PLPBP(gene name)|psi-mi:PLPBP(display_short)|uniprotkb:PROSC(gene name synonym)|uniprotkb:Proline synthase co-transcribed bacterial homolog protein(gene name synonym)|uniprotkb:Pyridoxal phosphate-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_009129.1|ensembl:ENSG00000147471(gene)|ensembl:ENST00000328195(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR011078(Predicted pyridoxal phosphate-dependent enzyme, YBL036C type)|interpro:IPR029066|mint:O94903 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:xrOEPMjG0y+otG21Al6Q0UuQcEY9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P22694 intact:EBI-25410664 intact:EBI-2679622|uniprotkb:Q14VH1|uniprotkb:Q5BNF3|uniprotkb:Q96B09|uniprotkb:Q59GC0|uniprotkb:Q5BNF2|uniprotkb:Q8IYR5|uniprotkb:Q8IZQ0|uniprotkb:Q5BNE9|uniprotkb:B4E2Q1|uniprotkb:Q7Z3M1|uniprotkb:Q5BNF1|uniprotkb:Q5CZ92|uniprotkb:Q5T1K3|uniprotkb:Q5BNF0|uniprotkb:B4DKB0|uniprotkb:B1APG4|ensembl:ENSP00000359723 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:kapcb_human(display_long)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001229786.1|refseq:NP_001229787.1|refseq:NP_001229788.1|refseq:NP_001229789.1|refseq:NP_001229790.1|refseq:NP_001229791.1|refseq:NP_002722.1|refseq:NP_891993.1|refseq:NP_997461.1|refseq:XP_005271076.1|refseq:XP_006710821.1|refseq:NP_001287844.1|refseq:NP_001287845.1|refseq:NP_001287846.1|ensembl:ENSG00000142875(gene)|ensembl:ENST00000370689(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P22694|interpro:IPR044109|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8963896|reactome:R-HSA-9010642|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:FEzsjRJZlkFu5+KK4abzu7oAY9E9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q4J6C6 intact:EBI-25410664 intact:EBI-949331|uniprotkb:A7E2X6|uniprotkb:O43163|uniprotkb:Q4J6C3|uniprotkb:Q4J6C4|uniprotkb:Q4ZG39|uniprotkb:Q6ZMW7|uniprotkb:Q96DW7|uniprotkb:D6W5A3|ensembl:ENSP00000260648|ensembl:ENSP00000386509|ensembl:ENSP00000386543|ensembl:ENSP00000386909|ensembl:ENSP00000391456|ensembl:ENSP00000409480 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:ppcel_human(display_long)|uniprotkb:KIAA0436(gene name synonym)|uniprotkb:Prolylendopeptidase-like(gene name synonym)|uniprotkb:PREPL(gene name)|psi-mi:PREPL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001035844.1|refseq:NP_001035845.1|refseq:NP_001165074.1|refseq:NP_001165077.1|refseq:NP_001165084.1|refseq:NP_001165088.1|refseq:NP_006027.2|refseq:XP_011531500.1|refseq:XP_011531502.1|refseq:XP_011531504.1|refseq:XP_016860873.1|refseq:XP_016860874.1|ensembl:ENSG00000138078(gene)|ensembl:ENST00000260648(transcript)|ensembl:ENST00000409272(transcript)|ensembl:ENST00000409936(transcript)|ensembl:ENST00000410081(transcript)|ensembl:ENST00000425263(transcript)|ensembl:ENST00000426481(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008233"(peptidase activity)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR023302|interpro:IPR029058 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:xn++9zR6AX/HzP4KzrriJR5IUTk9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O15355 intact:EBI-25410664 intact:EBI-725702|ensembl:ENSP00000342778 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O43164 intact:EBI-25410664 intact:EBI-1996038|uniprotkb:D3DSZ5|uniprotkb:Q68D49|uniprotkb:Q8N1G5|uniprotkb:A8K6U4|ensembl:ENSP00000354775|ensembl:ENSP00000355284 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:pja2_human(display_long)|uniprotkb:PJA2(gene name)|psi-mi:PJA2(display_short)|uniprotkb:KIAA0438(gene name synonym)|uniprotkb:RNF131(gene name synonym)|uniprotkb:RING finger protein 131(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase Praja-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_055634.3|refseq:XP_016865588.1|ensembl:ENSG00000198961(gene)|ensembl:ENST00000361189(transcript)|ensembl:ENST00000361557(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007616"(long-term memory)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035329"(hippo signaling)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR030639|mint:O43164|reactome:R-HSA-983168|dip:DIP-47040N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:z0OkXLozXymqwyF+xQR+PFa+bQI9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q29RF7 intact:EBI-25410664 intact:EBI-1175454|uniprotkb:Q2TTR5|uniprotkb:Q68DF7|uniprotkb:Q8N7J4|uniprotkb:Q8NG14|uniprotkb:Q9Y4D4|intact:EBI-2554552|ensembl:ENSP00000303427 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:pds5a_human(display_long)|uniprotkb:Sister chromatid cohesion protein 112(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 54 protein(gene name synonym)|uniprotkb:PDS5A(gene name)|psi-mi:PDS5A(display_short)|uniprotkb:KIAA0648(gene name synonym)|uniprotkb:PDS5(gene name synonym)|uniprotkb:PIG54(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000121892(gene)|ensembl:ENST00000303538(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039776|mint:Q29RF7|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|go:"GO:0005829"(cytosol)|refseq:NP_001093869.1|refseq:NP_001093870.1|refseq:XP_011511974.1|refseq:XP_016863417.1|dip:DIP-35419N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:PaZZmQCIaSIoxVpMuuERQbDLMpY9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P30101 intact:EBI-25410664 intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O75340 intact:EBI-25410664 intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q92621 intact:EBI-25410664 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P49902 intact:EBI-25410664 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9Y2X3 intact:EBI-25410664 intact:EBI-395469|uniprotkb:Q53SA4|uniprotkb:Q6PK08|uniprotkb:Q9P036|uniprotkb:Q9UFN3|ensembl:ENSP00000264279 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:nop58_human(display_long)|uniprotkb:NOP58(gene name)|psi-mi:NOP58(display_short)|uniprotkb:NOL5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:NOP5(gene name synonym)|uniprotkb:HSPC120(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_057018.1|ensembl:ENSG00000055044(gene)|ensembl:ENST00000264279(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|go:"GO:0016020"(membrane)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q9Y2X3|reactome:R-HSA-4570464|reactome:R-HSA-6790901|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|reactome:R-HSA-6791226|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|dip:DIP-32926N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:L7mE30ZNpQbKsQElFrrDMBQwG+w9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O00567 intact:EBI-25410664 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q16718 intact:EBI-25410664 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q99417 intact:EBI-25410664 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9Y2R9 intact:EBI-25410664 intact:EBI-1054973|uniprotkb:Q53GD6|uniprotkb:B2R9N5|ensembl:ENSP00000245539 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:rt07_human(display_long)|uniprotkb:bMRP-27a(gene name synonym)|uniprotkb:MRPS7(gene name)|psi-mi:MRPS7(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS7m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_057055.2|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR023798|interpro:IPR036823|mint:Q9Y2R9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125445(gene)|ensembl:ENST00000245539(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:hrz2XVS38Ex1z125QFx/n9oPsys9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9BYN8 intact:EBI-25410664 intact:EBI-721378|uniprotkb:Q96Q58|ensembl:ENSP00000369682 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:rt26_human(display_long)|uniprotkb:28S ribosomal protein S13, mitochondrial(gene name synonym)|uniprotkb:MRPS26(gene name)|psi-mi:MRPS26(display_short)|uniprotkb:RPMS13(gene name synonym)|uniprotkb:C20orf193(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_110438.1|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125901(gene)|ensembl:ENST00000380325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR026140|mint:Q9BYN8 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:ZygMazfhjHbx+aFhRkeG87c4L6E9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q13084 intact:EBI-25410664 intact:EBI-723426|uniprotkb:Q4TT39|uniprotkb:Q96S26|uniprotkb:Q9BQD8|uniprotkb:Q9BR04|ensembl:ENSP00000199706|ensembl:ENSP00000374326|ensembl:ENSP00000497004|uniprotkb:B2RCM4|uniprotkb:D3DU46 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:rm28_human(display_long)|uniprotkb:Melanoma antigen p15(gene name synonym)|uniprotkb:MRPL28(gene name)|psi-mi:MRPL28(display_short)|uniprotkb:MAAT1(gene name synonym)|uniprotkb:Melanoma-associated antigen recognized by T-lymphocytes(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL28m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_006419.2|rcsb pdb:3J7Y|ensembl:ENSG00000086504(gene)|ensembl:ENST00000199706(transcript)|ensembl:ENST00000389675(transcript)|ensembl:ENST00000648346(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|interpro:IPR026569|interpro:IPR034704|interpro:IPR037147|mint:Q13084|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011520653.1|refseq:XP_005255098.1|dip:DIP-61135N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:rgjK24sQlABM210ZM7T9mT2wxKs9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P33992 intact:EBI-25410664 intact:EBI-359410|ensembl:ENSP00000216122|uniprotkb:O60785|uniprotkb:Q14578|uniprotkb:Q9BTJ4|uniprotkb:Q9BWL8 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:mcm5_human(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:CDC46 homolog(gene name synonym)|uniprotkb:P1-CDC46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000100297(gene)|ensembl:ENST00000216122(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33992|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_006730.2|reactome:R-HSA-69052|reactome:R-HSA-68962|dip:DIP-27578N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:WjJ4lSpADQFtwT0WnumbRHl/lPw9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P83369 intact:EBI-25410664 intact:EBI-2626024|uniprotkb:A0AVQ1|uniprotkb:Q7Z7P0|uniprotkb:Q8N975|ensembl:ENSP00000286307 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:lsm11_human(display_long)|uniprotkb:LSM11(gene name)|psi-mi:LSM11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_775762.1|ensembl:ENSG00000155858(gene)|ensembl:ENST00000286307(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016604"(nuclear body)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034109|interpro:IPR039267|rcsb pdb:6V4X|reactome:R-HSA-111367|reactome:R-HSA-73856|reactome:R-HSA-77588 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:G1rWuaQHAPeHEf3rvzT/XkqvaYk9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q96AG4 intact:EBI-25410664 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q14739 intact:EBI-25410664 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q99714 intact:EBI-25410664 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9H583 intact:EBI-25410664 intact:EBI-1048716|uniprotkb:Q5T3Q8|uniprotkb:Q6P197|uniprotkb:Q9NW23|ensembl:ENSP00000355541 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:heat1_human(display_long)|uniprotkb:Protein BAP28(gene name synonym)|uniprotkb:HEATR1(gene name)|psi-mi:HEATR1(display_short)|uniprotkb:BAP28(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 10 homolog(gene name synonym)|uniprotkb:UTP10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_060542.4|ensembl:ENSG00000119285(gene)|ensembl:ENST00000366582(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022125|interpro:IPR040191|mint:Q9H583|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:0WoP84UUVfXWppmvCYa/n5GTzc89606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O00165 intact:EBI-25410664 intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9NY12 intact:EBI-25410664 intact:EBI-2510382|ensembl:ENSP00000226796|ensembl:ENSP00000378127|uniprotkb:Q5MJQ2 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:gar1_human(display_long)|uniprotkb:GAR1(gene name)|psi-mi:GAR1(display_short)|uniprotkb:NOLA1(gene name synonym)|uniprotkb:snoRNP protein GAR1(gene name synonym)|uniprotkb:Nucleolar protein family A member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000109534(gene)|ensembl:ENST00000226796(transcript)|ensembl:ENST00000394631(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007504(Gar1 protein RNA-binding region)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR038664|mint:Q9NY12|rcsb pdb:7BGB|reactome:R-HSA-171319|go:"GO:0000454"(snoRNA guided rRNA pseudouridine synthesis)|reactome:R-HSA-6790901|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|refseq:NP_061856.1|refseq:NP_127460.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:voLJvYfWyMWtTf0VSd7XeY3psC09606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9Y285 intact:EBI-25410664 intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_004452.1|ensembl:ENSG00000179115(gene)|ensembl:ENST00000314606(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|dip:DIP-53610N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9BS26 intact:EBI-25410664 intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSG00000023318(gene)|ensembl:ENST00000262455(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009986"(cell surface)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|go:"GO:0009100"(glycoprotein metabolic process)|refseq:NP_055866.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:TpwaFRifveb03iRPS2pEZve1kLA9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9UBM7 intact:EBI-25410664 intact:EBI-1054468|uniprotkb:O60492|uniprotkb:O60717|uniprotkb:B2R6Z2|ensembl:ENSP00000347717|ensembl:ENSP00000384739 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:dhcr7_human(display_long)|uniprotkb:"Sterol Delta(7)-reductase"(gene name synonym)|uniprotkb:DHCR7(gene name)|psi-mi:DHCR7(display_short)|uniprotkb:D7SR(gene name synonym)|uniprotkb:Delta7-sterol reductase(gene name synonym)|uniprotkb:Sterol reductase SR-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001157289.1|refseq:NP_001351.2|mint:Q9UBM7|reactome:R-HSA-2426168|reactome:R-HSA-6807047|reactome:R-HSA-6807062|interpro:IPR018083|ensembl:ENSG00000172893(gene)|ensembl:ENST00000355527(transcript)|ensembl:ENST00000407721(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0009918"(sterol delta7 reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016132"(brassinosteroid biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0047598"(7-dehydrocholesterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:op53bBpGaOM0Ysy4Bn5q6qXcKgI9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9BQ39 intact:EBI-25410664 intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P68400 intact:EBI-25410664 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P07498 intact:EBI-25410664 intact:EBI-2602175|uniprotkb:Q13575|ensembl:ENSP00000304822 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:cask_human(display_long)|uniprotkb:CSN3(gene name)|psi-mi:CSN3(display_short)|uniprotkb:CASK(gene name synonym)|uniprotkb:CSN10(gene name synonym)|uniprotkb:CSNK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:XP_011529922.1|refseq:NP_005203.2|ensembl:ENSG00000171209(gene)|ensembl:ENST00000304954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007595"(lactation)|go:"GO:0050821"(protein stabilization)|interpro:IPR000117(Kappa casein)|mint:P07498|reactome:R-HSA-5223345|refseq:XP_016863250.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:qmi1c3BKqV3ZBEVE8J7hTHJkvL09606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P05814 intact:EBI-25410664 intact:EBI-1642112|uniprotkb:Q4VAZ9|uniprotkb:Q9UCM5|ensembl:ENSP00000341030|ensembl:ENSP00000489488 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:casb_human(display_long)|uniprotkb:CSN2(gene name)|psi-mi:CSN2(display_short)|uniprotkb:CASB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001882.1|refseq:NP_001289699.1|refseq:XP_016863249.1|ensembl:ENSG00000135222(gene)|ensembl:ENSG00000283030(gene)|ensembl:ENST00000353151(transcript)|ensembl:ENST00000635174(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007595"(lactation)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR001588(Casein, alpha/beta)|interpro:IPR016345(Casein, beta)|interpro:IPR031305|mint:P05814|reactome:R-HSA-1251985 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:C7aq7sKFs3i5GOrPLzA0ZWDVefk9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O75390 intact:EBI-25410664 intact:EBI-487493|ensembl:ENSP00000342056|uniprotkb:Q71UT9|uniprotkb:Q7KZH0|uniprotkb:Q96FZ8|uniprotkb:Q9BWN8 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:cisy_human(display_long)|uniprotkb:CS(gene name)|psi-mi:CS(display_short)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) go:"GO:0006101"(citrate metabolic process)|refseq:NP_004068.2|ensembl:ENSG00000062485(gene)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000351328(transcript)|rcsb pdb:5UZQ|rcsb pdb:5UZR|reactome:R-HSA-1268020|reactome:R-HSA-71403|go:"GO:0070062"(extracellular exosome)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|rcsb pdb:5UZP - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:XKpnEsGOlGRNIAXMk4tTBH2okzo9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:O76031 intact:EBI-25410664 intact:EBI-1052667|uniprotkb:A1L428|uniprotkb:A8K8F1|uniprotkb:Q9H4D9|uniprotkb:B9EGI8|ensembl:ENSP00000300107 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:clpx_human(display_long)|uniprotkb:CLPX(gene name)|psi-mi:CLPX(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_006651.2|ensembl:ENSG00000166855(gene)|ensembl:ENST00000300107(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|go:"GO:0009841"(mitochondrial endopeptidase Clp complex)|mint:O76031|dip:DIP-50293N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:+SOis7raPEZqqeel6Y6dOWJcLj49606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:P12532 intact:EBI-25410664 intact:EBI-1050662|uniprotkb:Q0VAM3|uniprotkb:Q32NF6|uniprotkb:Q53FC4|uniprotkb:B4DIT8|uniprotkb:B7ZA09|ensembl:ENSP00000300283|ensembl:ENSP00000406577|ensembl:ENSP00000413165|ensembl:ENSP00000413255 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:kcru_human(display_long)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:CKMT1A(gene name)|psi-mi:CKMT1A(display_short)|uniprotkb:CKMT(gene name synonym)|uniprotkb:CKMT1B(gene name)|psi-mi:CKMT1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001015001.1|refseq:NP_066270.1|refseq:NP_001308855.1|refseq:NP_001308856.1|refseq:NP_001308857.1|refseq:XP_016877858.1|refseq:XP_016877859.1|refseq:XP_011519496.1|refseq:XP_011519497.1|refseq:XP_011519498.1|refseq:XP_011519499.1|ensembl:ENSG00000223572(gene)|ensembl:ENSG00000237289(gene)|ensembl:ENST00000300283(transcript)|ensembl:ENST00000413453(transcript)|ensembl:ENST00000434505(transcript)|ensembl:ENST00000441322(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12532|rcsb pdb:1QK1|reactome:R-HSA-71288 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:2ZgqE1XmbPXtjVY6lIdy+e0bSdU9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9Y6H1 intact:EBI-25410664 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9P1Y5 intact:EBI-25410664 intact:EBI-727407|uniprotkb:Q8NDF1|ensembl:ENSP00000160298 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:camp3_human(display_long)|uniprotkb:CAMSAP3(gene name)|psi-mi:CAMSAP3(display_short)|uniprotkb:KIAA1543(gene name synonym)|uniprotkb:Protein Nezha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) ensembl:ENSP00000160298|ensembl:ENSP00000416797|ensembl:ENST00000446248|refseq:NP_001073898.1|refseq:NP_065953.1|dip:DIP-52405N|ensembl:ENSG00000076826(gene)|ensembl:ENST00000160298(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003341"(cilium movement)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005915"(zonula adherens)|go:"GO:0005930"(axoneme)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030507"(spectrin binding)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031514"(motile cilium)|go:"GO:0033043"(regulation of organelle organization)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011033(PRC-barrel-like)|interpro:IPR014797(Protein of unknown function DUF1781)|interpro:IPR022613|interpro:IPR031372|interpro:IPR032940|interpro:IPR036872|interpro:IPR038209 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:G/MLMkIhEdjbAiwPu+xvqJFgvPg9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q9BZZ5 intact:EBI-25410664 intact:EBI-1048422|uniprotkb:O15441|uniprotkb:Q9Y4J7|uniprotkb:D3DR21|uniprotkb:B4DRJ2|uniprotkb:B4E283|uniprotkb:B4DGR0|ensembl:ENSP00000431391 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:api5_human(display_long)|uniprotkb:Fibroblast growth factor 2-interacting factor(gene name synonym)|uniprotkb:Protein XAGL(gene name synonym)|uniprotkb:Antiapoptosis clone 11 protein(gene name synonym)|uniprotkb:Cell migration-inducing gene 8 protein(gene name synonym)|uniprotkb:API5(gene name)|psi-mi:API5(display_short)|uniprotkb:MIG8(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_001136402.1|refseq:NP_001136403.1|refseq:NP_006586.1|refseq:NP_001230676.1|ensembl:ENSG00000166181(gene)|ensembl:ENST00000531273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR008383(Apoptosis inhibitory 5)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BZZ5|rcsb pdb:3U0R|rcsb pdb:3V6A|rcsb pdb:6L4O - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:WYNbM5GNolgFNszccnMEanszDgU9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZRI8-2 uniprotkb:Q8NI60 intact:EBI-25410664 intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739 psi-mi:q6zri82(display_long)|uniprotkb:ARHGAP36(gene name)|psi-mi:ARHGAP36(display_short) psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410669|imex:IM-26436-174 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZRI8-2(isoform-parent) refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Hi0b/Z2X3u3jNB2JSGbEWhHYzhQ9606 rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606 rigid:Z0LebZ5UD8UJWjPxpK18heu3LmY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14155-4 uniprotkb:P62306 intact:EBI-25410853|ensembl:ENSP00000364893 intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735 psi-mi:q14155-4(display_long)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410864|imex:IM-26436-316 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|intact:EBI-717515(isoform-parent) refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606 rigid:C3i0FSyCk3uqOTiKz+22jrXA8cE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14155-4 uniprotkb:P28072 intact:EBI-25410853|ensembl:ENSP00000364893 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:q14155-4(display_long)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410864|imex:IM-26436-316 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|intact:EBI-717515(isoform-parent) refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 rigid:C3i0FSyCk3uqOTiKz+22jrXA8cE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14155-4 uniprotkb:Q9Y2X7 intact:EBI-25410853|ensembl:ENSP00000364893 intact:EBI-466061|uniprotkb:Q86SS0|uniprotkb:Q9BRJ4|uniprotkb:B4DSV3|ensembl:ENSP00000225394|uniprotkb:B4DGU9 psi-mi:q14155-4(display_long)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:git1_human(display_long)|uniprotkb:GIT1(gene name)|psi-mi:GIT1(display_short)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Cool-associated and tyrosine-phosphorylated protein 1(gene name synonym)|uniprotkb:p95-APP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410864|imex:IM-26436-316 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|intact:EBI-717515(isoform-parent) refseq:NP_001078923.1|refseq:NP_054749.2|ensembl:ENSG00000108262(gene)|ensembl:ENST00000225394(transcript)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045820"(negative regulation of glycolytic process)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|go:"GO:0046872"(metal ion binding)|interpro:IPR020683|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|go:"GO:0048666"(neuron development)|go:"GO:0061743"(motor learning)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0106015"(negative regulation of inflammatory response to wounding)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR038508|interpro:IPR001164(Arf GTPase activating protein)|mint:Q9Y2X7|interpro:IPR002110(Ankyrin)|reactome:R-HSA-3928664|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9619229 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rogid:9POm+EVvD4/BQh6bApnpXCAZyZo9606 rigid:C3i0FSyCk3uqOTiKz+22jrXA8cE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14155-4 uniprotkb:Q86T24 intact:EBI-25410853|ensembl:ENSP00000364893 intact:EBI-2515625|ensembl:ENSP00000314153|ensembl:ENSP00000450969|uniprotkb:Q7Z361|uniprotkb:Q8N3P0|uniprotkb:Q8IVP6|uniprotkb:O00319|uniprotkb:B2R5U6 psi-mi:q14155-4(display_long)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:kaiso_human(display_long)|uniprotkb:ZBTB33(gene name)|psi-mi:ZBTB33(display_short)|uniprotkb:KAISO(gene name synonym)|uniprotkb:ZNF348(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 33(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410864|imex:IM-26436-316 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|intact:EBI-717515(isoform-parent) ensembl:ENSG00000177485(gene)|ensembl:ENST00000326624(transcript)|ensembl:ENST00000557385(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2LT7|rcsb pdb:3FKC|rcsb pdb:3M4T|rcsb pdb:3M8V|rcsb pdb:4F6M|rcsb pdb:4F6N|rcsb pdb:5VMU|rcsb pdb:5VMV|rcsb pdb:5VMW|rcsb pdb:5VMX|rcsb pdb:5VMY|rcsb pdb:5VMZ|rcsb pdb:6DF5|rcsb pdb:6DF8|rcsb pdb:6DF9|rcsb pdb:6DFA|rcsb pdb:6DFB|rcsb pdb:6DFC|rcsb pdb:6V8U|refseq:NP_001171671.1|refseq:NP_006768.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rogid:nD+3FCTCYxUrXZXpBW5Co1V0CHc9606 rigid:C3i0FSyCk3uqOTiKz+22jrXA8cE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14155-4 uniprotkb:Q9Y5L4 intact:EBI-25410853|ensembl:ENSP00000364893 intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570 psi-mi:q14155-4(display_long)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410864|imex:IM-26436-316 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|intact:EBI-717515(isoform-parent) refseq:NP_036590.1|ensembl:ENSG00000099800(gene)|ensembl:ENST00000215570(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5L4|reactome:R-HSA-1268020 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606 rigid:C3i0FSyCk3uqOTiKz+22jrXA8cE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14155-4 uniprotkb:Q13177 intact:EBI-25410853|ensembl:ENSP00000364893 intact:EBI-1045887|uniprotkb:Q13154|uniprotkb:Q6ISC3|ensembl:ENSP00000314067|intact:EBI-28976120 psi-mi:q14155-4(display_long)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:pak2_human(display_long)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:PAK65(gene name synonym)|uniprotkb:S6/H4 kinase(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410864|imex:IM-26436-316 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|intact:EBI-717515(isoform-parent) ensembl:ENSP00000314067|ensembl:ENSG00000180370(gene)|ensembl:ENST00000327134(transcript)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035064|interpro:IPR035065|interpro:IPR036936|mint:Q13177|rcsb pdb:3PCS|reactome:R-HSA-164944|reactome:R-HSA-202433|reactome:R-HSA-211728|reactome:R-HSA-211733|reactome:R-HSA-211736|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-445355|reactome:R-HSA-5621575|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-5218920|refseq:NP_002568.2|refseq:XP_011511172.1|refseq:XP_016861990.1|dip:DIP-38249N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rogid:BLFG1UZy6GUy26Hd7VDehsIq3/I9606 rigid:C3i0FSyCk3uqOTiKz+22jrXA8cE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14155-4 uniprotkb:Q13153 intact:EBI-25410853|ensembl:ENSP00000364893 intact:EBI-1307|uniprotkb:O75561|uniprotkb:Q13567|uniprotkb:Q32M53|uniprotkb:Q32M54|uniprotkb:Q86W79|intact:EBI-28976107|ensembl:ENSP00000348696 psi-mi:q14155-4(display_long)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:pak1_human(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym)|uniprotkb:Alpha-PAK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410864|imex:IM-26436-316 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|intact:EBI-717515(isoform-parent) refseq:NP_001122092.1|refseq:NP_002567.3|ensembl:ENST00000278568|ensembl:ENSP00000278568|ensembl:ENSP00000348696|go:"GO:0001666"(response to hypoxia)|go:"GO:0001726"(ruffle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|refseq:XP_011543382.1|refseq:XP_011543383.1|refseq:XP_011543384.1|refseq:XP_011543385.1|refseq:XP_011543386.1|refseq:XP_016873335.1|refseq:XP_016873336.1|refseq:XP_016873337.1|refseq:XP_016873338.1|refseq:XP_016873339.1|dip:DIP-31016N|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:Q13153|rcsb pdb:1F3M|rcsb pdb:1YHV|rcsb pdb:1YHW|rcsb pdb:1ZSG|rcsb pdb:2HY8|rcsb pdb:2QME|rcsb pdb:3DVP|rcsb pdb:3FXZ|rcsb pdb:3FY0|rcsb pdb:3Q4Z|rcsb pdb:3Q52|rcsb pdb:3Q53|rcsb pdb:4DAW|rcsb pdb:4EQC|rcsb pdb:4O0R|rcsb pdb:4O0T|rcsb pdb:4P90|rcsb pdb:4ZJI|rcsb pdb:4ZJJ|rcsb pdb:4ZLO|rcsb pdb:4ZY4|rcsb pdb:4ZY5|rcsb pdb:4ZY6|rcsb pdb:5DEW|rcsb pdb:5DEY|rcsb pdb:5DFP|rcsb pdb:5IME|rcsb pdb:5KBQ|rcsb pdb:5KBR|rcsb pdb:6B16|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-2871796|reactome:R-HSA-376172|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-445144|reactome:R-HSA-445355|reactome:R-HSA-5218920|reactome:R-HSA-5621575|reactome:R-HSA-5625740|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606 rigid:C3i0FSyCk3uqOTiKz+22jrXA8cE false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:Q9H936 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-1050588|uniprotkb:Q8TBU8|uniprotkb:A8K366|uniprotkb:C9J1H6|uniprotkb:E9PJD3|uniprotkb:E9PKB2|uniprotkb:E9PL68|uniprotkb:E9PN26|uniprotkb:E9PNQ3|uniprotkb:E9PP01|uniprotkb:E9PR97|ensembl:ENSP00000322020|ensembl:ENSP00000437236|ensembl:ENSP00000486058 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:ghc1_human(display_long)|uniprotkb:"Glutamate/H(+) symporter 1"(gene name synonym)|uniprotkb:Solute carrier family 25 member 22(gene name synonym)|uniprotkb:SLC25A22(gene name)|psi-mi:SLC25A22(display_short)|uniprotkb:GC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_001177989.1|refseq:NP_001177990.1|refseq:NP_078974.1|ensembl:ENSG00000177542(gene)|ensembl:ENST00000320230(transcript)|ensembl:ENST00000531214(transcript)|ensembl:ENST00000628067(transcript)|go:"GO:0005280"("amino acid:proton symporter activity")|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006811"(ion transport)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-HSA-428643|refseq:XP_011518671.1|refseq:XP_011518672.1|refseq:XP_011518673.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:B1e6uu3Vx73qy/JrHS7p63p0QMM9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:P50454 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:O00148 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:P48047 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:O14980 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:O75083 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-351917|uniprotkb:O75313|uniprotkb:Q8N6E5|uniprotkb:Q9UG05|uniprotkb:Q9UG78|uniprotkb:A8MPU4|uniprotkb:Q9UQE0|uniprotkb:A8K6E9|ensembl:ENSP00000371890|ensembl:ENSP00000427687 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:wdr1_human(display_long)|uniprotkb:WDR1(gene name)|psi-mi:WDR1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)|uniprotkb:NORI-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_005103.2|refseq:NP_059830.1|ensembl:ENSG00000071127(gene)|ensembl:ENST00000382452(transcript)|ensembl:ENST00000499869(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O75083|reactome:R-HSA-114608 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:ewKq6uA2Wrg/uK31ayOoenA9Gv49606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:P21796 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:Q9NZR1 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-4289968|uniprotkb:B4DEW6|ensembl:ENSP00000249700 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:tmod2_human(display_long)|uniprotkb:TMOD2(gene name)|psi-mi:TMOD2(display_short)|uniprotkb:NTMOD(gene name synonym)|uniprotkb:Neuronal tropomodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 ensembl:ENSG00000128872(gene)|ensembl:ENST00000249700(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030426"(growth cone)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051694"(pointed-end actin filament capping)|interpro:IPR004934(Tropomodulin)|interpro:IPR030130|interpro:IPR032675|reactome:R-HSA-390522|refseq:NP_001136357.1|refseq:NP_055363.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:km9yOQf3wlXkMxXa/wKFxquWej09606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:P28289 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-2659631|uniprotkb:B2RB77|uniprotkb:Q5T7W3|uniprotkb:Q9BUF1|ensembl:ENSP00000259365|ensembl:ENSP00000378637|intact:EBI-10965302 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:tmod1_human(display_long)|uniprotkb:Erythrocyte tropomodulin(gene name synonym)|uniprotkb:D9S57E(gene name synonym)|uniprotkb:TMOD(gene name synonym)|uniprotkb:TMOD1(gene name)|psi-mi:TMOD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_001159588.1|refseq:NP_003266.1|ensembl:ENST00000259365(transcript)|ensembl:ENST00000395211(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0070307"(lens fiber cell development)|interpro:IPR004934(Tropomodulin)|interpro:IPR030135|interpro:IPR032675|mint:P28289|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4Z8G|rcsb pdb:4Z94|reactome:R-HSA-390522|ensembl:ENSG00000136842(gene) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:xbmnoh2E0cuP4ZYmnhlOo8QDnHw9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:Q13148 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:P61619 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-358919|uniprotkb:Q5JPF8|uniprotkb:P38378|uniprotkb:P57726|uniprotkb:Q8N3U3|uniprotkb:Q8NC71|uniprotkb:Q9BU16|uniprotkb:Q9Y2R3|uniprotkb:Q8N0Z4|ensembl:ENSP00000243253 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:s61a1_human(display_long)|uniprotkb:SEC61A1(gene name)|psi-mi:SEC61A1(display_short)|uniprotkb:SEC61A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_037468.1|ensembl:ENSG00000058262(gene)|ensembl:ENST00000243253(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0039019"(pronephric nephron development)|go:"GO:0043022"(ribosome binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|mint:P61619|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:C+EzS02H/FYMX2nyfksXpRMs8G09606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:Q96SB3 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-351275|uniprotkb:Q8TCR9|intact:EBI-28984643|ensembl:ENSP00000478767|intact:EBI-4401886|uniprotkb:D3DTX6 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:neb2_human(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:PPP1R9B(gene name)|psi-mi:PPP1R9B(display_short)|uniprotkb:PPP1R6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 ensembl:ENSG00000108819(gene)|ensembl:ENST00000612501(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035094"(response to nicotine)|go:"GO:0035690"|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060179"(male mating behavior)|go:"GO:0061458"(reproductive system development)|go:"GO:0071315"(cellular response to morphine)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097338"(response to clozapine)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903119"(protein localization to actin cytoskeleton)|go:"GO:1904372"(positive regulation of protein localization to actin cortical patch)|go:"GO:1904373"(response to kainic acid)|go:"GO:1904386"(response to L-phenylalanine derivative)|go:"GO:1990778"(protein localization to cell periphery)|go:"GO:1990780"(cytoplasmic side of dendritic spine plasma membrane)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029921|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q96SB3|ensembl:ENSP00000478767|refseq:NP_115984.3 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:X6fQLpaYhXCqzRlQNEoX67P/HbU9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:Q6S8J3 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-4289913|uniprotkb:Q6S8J4|uniprotkb:Q6S8J8|uniprotkb:Q6S8J5|ensembl:ENSP00000439189|ensembl:ENSP00000507284 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:potee_human(display_long)|uniprotkb:POTEE(gene name)|psi-mi:POTEE(display_short)|uniprotkb:A26C1A(gene name synonym)|uniprotkb:POTE2(gene name synonym)|uniprotkb:ANKRD26-like family C member 1A(gene name synonym)|uniprotkb:Prostate, ovary, testis-expressed protein on chromosome 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 ensembl:ENSG00000188219(gene)|ensembl:ENST00000356920(transcript)|ensembl:ENST00000683005(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129|reactome:R-HSA-9035034|interpro:IPR020902|refseq:NP_001077007.1|refseq:XP_016859650.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:LMuv4bmAG2/uPyH5LR9q+ickvWI9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:Q15149 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:O60331 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-8869029|uniprotkb:B7Z9E7|uniprotkb:C6GIJ7|uniprotkb:C6GIJ8|uniprotkb:Q7LE07|ensembl:ENSP00000335333 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:pi51c_human(display_long)|uniprotkb:PIP5K1C(gene name)|psi-mi:PIP5K1C(display_short)|uniprotkb:KIAA0589(gene name synonym)|uniprotkb:Type I phosphatidylinositol 4-phosphate 5-kinase gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 ensembl:ENSP00000335333|ensembl:ENST00000537021|ensembl:ENSP00000444779|ensembl:ENST00000539785|ensembl:ENSP00000445992|ensembl:ENST00000589578|ensembl:ENSP00000466363|refseq:NP_001287778.1|refseq:NP_001182662.1|refseq:NP_036530.1|dip:DIP-39809N|ensembl:ENSG00000186111(gene)|ensembl:ENST00000335312(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|rcsb pdb:2G35|rcsb pdb:3H1Z|rcsb pdb:3H85|reactome:R-HSA-1660499|reactome:R-HSA-399955|reactome:R-HSA-6811558|reactome:R-HSA-8856828 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:Xle7kUnkAh2gtQLx2/gl7d2Gz049606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:O43347 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-726515|uniprotkb:Q96PU0|uniprotkb:Q96PU1|uniprotkb:Q96PU2|uniprotkb:Q96PU3|intact:EBI-28986772|ensembl:ENSP00000257552 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:msi1h_human(display_long)|uniprotkb:MSI1(gene name)|psi-mi:MSI1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_002433.1|ensembl:ENSP00000257552|refseq:XP_011536663.1|ensembl:ENSG00000135097(gene)|ensembl:ENST00000257552(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0007399"(nervous system development)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|reactome:R-HSA-9010553 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:41/VCaTWDXjzXSisiAoG19FFVF09606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:O75955 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:O14579 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:Q99653 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|ensembl:ENSP00000335632 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_009167.1|ensembl:ENSG00000187446(gene)|ensembl:ENST00000334660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|reactome:R-HSA-2160916 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:P23528 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629|ensembl:ENSP00000432660 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_005498.1|ensembl:ENSG00000172757(gene)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|ensembl:ENST00000308162(transcript)|ensembl:ENST00000525451(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0031258"(lamellipodium membrane)|dip:DIP-33000N - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:Q6QNY1 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:O14639 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-487024|uniprotkb:A6NI16|uniprotkb:Q5T6N3|uniprotkb:Q5JVV1|uniprotkb:Q15039|uniprotkb:Q68CQ9|uniprotkb:Q9BUP1|uniprotkb:Q5T6N5|uniprotkb:B3KVH2|uniprotkb:Q5T6N2|uniprotkb:A6NJ06|uniprotkb:A8MXA9|uniprotkb:Q5JVV2|ensembl:ENSP00000277895 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:ablm1_human(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Actin-binding double zinc finger protein(gene name synonym)|uniprotkb:Limatin(gene name synonym)|uniprotkb:ABLIM1(gene name)|psi-mi:ABLIM1(display_short)|uniprotkb:ABLIM(gene name synonym)|uniprotkb:KIAA0059(gene name synonym)|uniprotkb:LIMAB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 refseq:NP_001003407.1|refseq:NP_002304.3|refseq:NP_006711.3|ensembl:ENSG00000099204(gene)|ensembl:ENST00000277895(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028448|interpro:IPR032402|interpro:IPR036886|mint:O14639|reactome:R-HSA-418885|go:"GO:0030032"(lamellipodium assembly)|refseq:NP_001309811.1|refseq:NP_001309821.1|refseq:NP_001309822.1|refseq:NP_001309825.1 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:Dsx3GrmdlsYUmQvuW59NfYF7MJg9606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96D37 uniprotkb:P28288 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410801|imex:IM-26436-224 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798 - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606 rigid:QviVRd2zETNnggNvC2SfEtgoNmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q9GZT3 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-1050793|uniprotkb:J3KMY7|ensembl:ENSP00000450909|intact:EBI-10967524 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:slirp_human(display_long)|uniprotkb:SLIRP(gene name)|psi-mi:SLIRP(display_short)|uniprotkb:C14orf156(gene name synonym)|uniprotkb:DC23(orf name)|uniprotkb:DC50(orf name)|uniprotkb:PD04872(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_112487.1|refseq:NP_001254792.1|refseq:NP_001254793.1|ensembl:ENSG00000119705(gene)|ensembl:ENST00000557342(transcript)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034152|interpro:IPR035979|mint:Q9GZT3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:8sPWOtmxPTOVlthXwBiIIp/+6go9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:P54886 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q9H2K2 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-4398527|uniprotkb:Q9H8F2|uniprotkb:Q9HAS4|uniprotkb:B2RBD3|ensembl:ENSP00000360689 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:tnks2_human(display_long)|uniprotkb:TNKS2(gene name)|psi-mi:TNKS2(display_short)|uniprotkb:PARP5B(gene name synonym)|uniprotkb:TANK2(gene name synonym)|uniprotkb:TNKL(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5B(gene name synonym)|uniprotkb:TNKS-2(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase 2(gene name synonym)|uniprotkb:Tankyrase II(gene name synonym)|uniprotkb:Tankyrase-like protein(gene name synonym)|uniprotkb:Tankyrase-related protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 6(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-2(gene name synonym)|uniprotkb:Tankyrase-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_079511.1|dip:DIP-42098N|rcsb pdb:3P0Q|rcsb pdb:3TWQ|rcsb pdb:3TWR|rcsb pdb:3TWS|rcsb pdb:3TWT|rcsb pdb:3TWU|rcsb pdb:3TWV|rcsb pdb:3TWW|rcsb pdb:3TWX|rcsb pdb:3U9H|rcsb pdb:3U9Y|rcsb pdb:3UA9|rcsb pdb:3W51|rcsb pdb:4AVU|rcsb pdb:4AVW|rcsb pdb:4BFP|rcsb pdb:4BJ9|rcsb pdb:4BJB|rcsb pdb:4BJC|rcsb pdb:4BS4|rcsb pdb:4BU3|rcsb pdb:4BU5|rcsb pdb:4BU6|rcsb pdb:4BU7|rcsb pdb:4BU8|rcsb pdb:4BU9|rcsb pdb:4BUA|rcsb pdb:4BUD|rcsb pdb:4BUE|rcsb pdb:4BUF|rcsb pdb:4BUI|rcsb pdb:4BUS|rcsb pdb:4BUT|rcsb pdb:4BUU|rcsb pdb:4BUV|rcsb pdb:4BUW|rcsb pdb:4BUX|rcsb pdb:4BUY|rcsb pdb:4HKI|rcsb pdb:4HKK|rcsb pdb:4HKN|ensembl:ENSG00000107854(gene)|ensembl:ENST00000371627(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|mint:Q9H2K2|rcsb pdb:2Y0I|rcsb pdb:3KR7|rcsb pdb:3KR8|rcsb pdb:3MHJ|rcsb pdb:3MHK|rcsb pdb:3P0N|rcsb pdb:3P0P|rcsb pdb:6TKP|rcsb pdb:6TKQ|rcsb pdb:6TKR|rcsb pdb:6TKS|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:6TKN|rcsb pdb:4HL5|rcsb pdb:4HLF|rcsb pdb:4HLG|rcsb pdb:4HLH|rcsb pdb:4HLK|rcsb pdb:4HLM|rcsb pdb:4HMH|rcsb pdb:4HYF|rcsb pdb:4IUE|rcsb pdb:4J1Z|rcsb pdb:4J21|rcsb pdb:4J22|rcsb pdb:4J3L|rcsb pdb:4J3M|rcsb pdb:4KZL|rcsb pdb:4KZQ|rcsb pdb:4KZU|rcsb pdb:4L09|rcsb pdb:4L0B|rcsb pdb:4L0I|rcsb pdb:4L0T|rcsb pdb:4L0V|rcsb pdb:4L10|rcsb pdb:4L2F|rcsb pdb:4L2G|rcsb pdb:4L2K|rcsb pdb:4L31|rcsb pdb:4L32|rcsb pdb:4L33|rcsb pdb:4L34|rcsb pdb:4M7B|rcsb pdb:4PML|rcsb pdb:4PNL|rcsb pdb:4PNM|rcsb pdb:4PNN|rcsb pdb:4PNQ|rcsb pdb:4PNR|rcsb pdb:4PNS|rcsb pdb:4PNT|rcsb pdb:4TJU|rcsb pdb:4TJW|rcsb pdb:4TJY|rcsb pdb:4TK0|rcsb pdb:4TK5|rcsb pdb:4TKF|rcsb pdb:4TKG|rcsb pdb:4TKI|rcsb pdb:4UFU|rcsb pdb:4UFY|rcsb pdb:4UHG|rcsb pdb:4UI3|rcsb pdb:4UI4|rcsb pdb:4UI5|rcsb pdb:4UI6|rcsb pdb:4UI7|rcsb pdb:4UI8|rcsb pdb:4UVL|rcsb pdb:4UVN|rcsb pdb:4UVO|rcsb pdb:4UVP|rcsb pdb:4UVS|rcsb pdb:4UVT|rcsb pdb:4UVU|rcsb pdb:4UVV|rcsb pdb:4UVW|rcsb pdb:4UVX|rcsb pdb:4UVY|rcsb pdb:4UVZ|rcsb pdb:4UX4|rcsb pdb:4W5I|rcsb pdb:4Z68|rcsb pdb:5ADQ|rcsb pdb:5ADR|rcsb pdb:5ADS|rcsb pdb:5ADT|rcsb pdb:5AEH|rcsb pdb:5AKU|rcsb pdb:5AKW|rcsb pdb:5AL1|rcsb pdb:5AL2|rcsb pdb:5AL3|rcsb pdb:5AL4|rcsb pdb:5AL5|rcsb pdb:5BXO|rcsb pdb:5BXU|rcsb pdb:5C5P|rcsb pdb:4L0S|rcsb pdb:5C5Q|rcsb pdb:5C5R|rcsb pdb:5DCZ|rcsb pdb:5FPF|rcsb pdb:5FPG|rcsb pdb:5JRT|rcsb pdb:5NOB|rcsb pdb:5NSP|rcsb pdb:5NUT|rcsb pdb:5OWS|rcsb pdb:5OWT|rcsb pdb:6TG4|rcsb pdb:6TKM - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:pf0mQR/in4ShtYc1xmCF042/v/A9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:O95271 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-1105254|uniprotkb:O95272|uniprotkb:Q4G0F2|intact:EBI-28985643|ensembl:ENSP00000311579 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:tnks1_human(display_long)|uniprotkb:TNKS(gene name)|psi-mi:TNKS(display_short)|uniprotkb:PARP5A(gene name synonym)|uniprotkb:PARPL(gene name synonym)|uniprotkb:TIN1(gene name synonym)|uniprotkb:TINF1(gene name synonym)|uniprotkb:TNKS1(gene name synonym)|uniprotkb:Tankyrase I(gene name synonym)|uniprotkb:TNKS-1(gene name synonym)|uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 5A(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 5(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-1(gene name synonym)|uniprotkb:Tankyrase-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_003738.2|rcsb pdb:5JHQ|rcsb pdb:5JTI|rcsb pdb:5JU5|rcsb pdb:5KNI|rcsb pdb:6QXU|rcsb pdb:6URQ|reactome:R-HSA-201681|reactome:R-HSA-4641257|reactome:R-HSA-5545619|reactome:R-HSA-5689880|reactome:R-HSA-8948751|rcsb pdb:5GP7|ensembl:ENSP00000311579|ensembl:ENSG00000173273(gene)|ensembl:ENST00000310430(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051028"(mRNA transport)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904743"(negative regulation of telomeric DNA binding)|go:"GO:1904908"(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR028731|interpro:IPR036770|mint:O95271|rcsb pdb:2RF5|rcsb pdb:3UDD|rcsb pdb:3UH2|rcsb pdb:3UH4|rcsb pdb:4DVI|rcsb pdb:4I9I|go:"GO:0016055"(Wnt signaling pathway)|rcsb pdb:4K4F|rcsb pdb:4KRS|rcsb pdb:4LI6|rcsb pdb:4LI7|rcsb pdb:4LI8|rcsb pdb:4MSG|rcsb pdb:4MSK|rcsb pdb:4MT9|rcsb pdb:4N3R|rcsb pdb:4N4V|rcsb pdb:4OA7|rcsb pdb:4TOR|rcsb pdb:4TOS|rcsb pdb:4U6A|rcsb pdb:4UUH|rcsb pdb:4UW1|rcsb pdb:4K4E|rcsb pdb:4W5S|rcsb pdb:4W6E|rcsb pdb:5EBT|rcsb pdb:5ECE|rcsb pdb:5ETY|dip:DIP-36652N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:0WKEfg5OMAISQutoJb2w+hBfmOU9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q08188 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-1050019|uniprotkb:A8K5N6|uniprotkb:Q32MM0|uniprotkb:O95933|uniprotkb:Q32ML9|uniprotkb:B2RCR6|uniprotkb:D3DVX1|ensembl:ENSP00000370867 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:tgm3_human(display_long)|uniprotkb:Transglutaminase-3(gene name synonym)|uniprotkb:TGM3(gene name)|psi-mi:TGM3(display_short)|uniprotkb:Transglutaminase E(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_003236.3|ensembl:ENSG00000125780(gene)|ensembl:ENST00000381458(transcript)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031424"(keratinization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043163"(cell envelope organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:Q08188|rcsb pdb:1L9M|rcsb pdb:1L9N|rcsb pdb:1NUD|rcsb pdb:1NUF|rcsb pdb:1NUG - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:5UuVUvhYOaQcLJQO2myrilPgFFw9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q9BXP5 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|ensembl:ENSP00000480421|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) ensembl:ENST00000611405(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|reactome:R-HSA-6807505|reactome:R-HSA-72163|ensembl:ENSG00000087087(gene)|refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q5JUX0 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-1642527|uniprotkb:Q8N5D9|uniprotkb:B7Z8W2|uniprotkb:B2RUW3|ensembl:ENSP00000364054|ensembl:ENSP00000491179|ensembl:ENSP00000491624|ensembl:ENSP00000491751|ensembl:ENSP00000492344|ensembl:ENSP00000492381|ensembl:ENSP00000492795 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:spin3_human(display_long)|uniprotkb:SPIN3(gene name)|psi-mi:SPIN3(display_short)|uniprotkb:Spindlin-like protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_001010862.2|refseq:XP_006724640.1|refseq:XP_006724641.1|refseq:XP_016884804.1|ensembl:ENSG00000204271(gene)|ensembl:ENST00000374919(transcript)|ensembl:ENST00000638257(transcript)|ensembl:ENST00000638289(transcript)|ensembl:ENST00000638386(transcript)|ensembl:ENST00000638712(transcript)|ensembl:ENST00000639007(transcript)|ensembl:ENST00000639605(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0035064"(methylated histone binding)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029567|interpro:IPR042567|mint:Q5JUX0|rcsb pdb:5A1H - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:Z4PHGiFUPGeFRxSjg6rzBFnXv7g9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:P29508 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-359110|uniprotkb:Q53H28|uniprotkb:Q86VF3|uniprotkb:Q86W04|uniprotkb:Q8IWL4|uniprotkb:Q8IXI3|uniprotkb:Q9BYF8|uniprotkb:Q53YB5|uniprotkb:Q96J21|uniprotkb:B2RBT5|uniprotkb:A6NDM2|uniprotkb:B3W5Y6|ensembl:ENSP00000283752 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:spb3_human(display_long)|uniprotkb:SERPINB3(gene name)|psi-mi:SERPINB3(display_short)|uniprotkb:SCCA(gene name synonym)|uniprotkb:SCCA1(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen 1(gene name synonym)|uniprotkb:Protein T4-A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_008850.1|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038001"(paracrine signaling)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P29508|rcsb pdb:2ZV6|rcsb pdb:4ZK0|rcsb pdb:4ZK3|reactome:R-HSA-6798695|ensembl:ENSG00000057149(gene)|ensembl:ENST00000283752(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:Q6rcSr7BU3XXRUX39SbdLT6Nm5s9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q8WUA2 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-2513119|ensembl:ENSP00000253329|uniprotkb:B2RD34|uniprotkb:Q7Z3Q5 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:ppil4_human(display_long)|uniprotkb:PPIL4(gene name)|psi-mi:PPIL4(display_short)|uniprotkb:Cyclophilin-like protein PPIL4(gene name synonym)|uniprotkb:Rotamase PPIL4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029000|interpro:IPR035538|interpro:IPR035542|interpro:IPR035979|mint:Q8WUA2|reactome:R-HSA-72163|go:"GO:0005829"(cytosol)|ensembl:ENSG00000131013(gene)|ensembl:ENST00000253329(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_624311.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:kxM/VRcLUG5M5FAlHuuAKRBKrd89606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q96PX9 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-11741362|ensembl:ENSP00000283426 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:P12273 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q96RR1 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-716458|uniprotkb:Q6MZX2|uniprotkb:Q96RR0|uniprotkb:Q6PJP5|uniprotkb:B2CQL2|ensembl:ENSP00000309595 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:peo1_human(display_long)|uniprotkb:TWNK(gene name)|psi-mi:TWNK(display_short)|uniprotkb:C10orf2(gene name synonym)|uniprotkb:PEO1(gene name synonym)|uniprotkb:Progressive external ophthalmoplegia 1 protein(gene name synonym)|uniprotkb:T7 gp4-like protein with intramitochondrial nucleoid localization(gene name synonym)|uniprotkb:T7-like mitochondrial DNA helicase(gene name synonym)|uniprotkb:Twinkle protein, mitochondrial(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_001157284.1|refseq:NP_068602.2|ensembl:ENST00000311916(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|ensembl:ENSG00000107815(gene)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR007694(DNA helicase, DnaB-like, C-terminal)|interpro:IPR027417|interpro:IPR034154|mint:Q96RR1|reactome:R-HSA-2151201 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:asX2NETd8o4GZrWe8gIUntbtUpA9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q5T749 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-10981970|ensembl:ENSP00000475216 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:kprp_human(display_long)|uniprotkb:KPRP(gene name)|psi-mi:KPRP(display_short)|uniprotkb:C1orf45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_001020402.1|refseq:XP_011507873.1|ensembl:ENSG00000203786(gene)|ensembl:ENST00000606109(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0070062"(extracellular exosome)|mint:Q5T749 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:y5a5hbvzlv8VDmCY169of+RrNKo9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q15018 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-1056583|uniprotkb:Q96H11|uniprotkb:B4DKR2|intact:EBI-28981592|ensembl:ENSP00000298492 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:abrx2_human(display_long)|uniprotkb:ABRAXAS2(gene name)|psi-mi:ABRAXAS2(display_short)|uniprotkb:ABRO1(gene name synonym)|uniprotkb:Abraxas brother protein 1(gene name synonym)|uniprotkb:FAM175B(gene name synonym)|uniprotkb:KIAA0157(gene name synonym)|uniprotkb:Protein FAM175B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) ensembl:ENSP00000298492|refseq:NP_115558.3|ensembl:ENSG00000165660(gene)|ensembl:ENST00000298492(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR023238|interpro:IPR023240|interpro:IPR037518|mint:Q15018|rcsb pdb:6H3C|rcsb pdb:6R8F|reactome:R-HSA-5689901 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:fYZdQpH09qcBBUV1IKV2wsRk4m89606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q9Y463 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-634187|uniprotkb:O75258|uniprotkb:O75788|uniprotkb:O75789|ensembl:ENSP00000312789|ensembl:ENSP00000469863|ensembl:ENSP00000485915|ensembl:ENSP00000486377 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:dyr1b_human(display_long)|uniprotkb:Mirk protein kinase(gene name synonym)|uniprotkb:Minibrain-related kinase(gene name synonym)|uniprotkb:DYRK1B(gene name)|psi-mi:DYRK1B(display_short)|uniprotkb:MIRK(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_004705.1|refseq:NP_006474.1|refseq:NP_006475.1|refseq:XP_005259455.1|ensembl:ENSG00000105204(gene)|ensembl:ENSG00000281320(gene)|ensembl:ENST00000323039(transcript)|ensembl:ENST00000593685(transcript)|ensembl:ENST00000625757(transcript)|ensembl:ENST00000631090(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007520"(myoblast fusion)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028318|interpro:IPR044131|mint:Q9Y463|go:"GO:0106310"(protein serine kinase activity) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:MaG/ZUw0KMo5JxQdeIhMu0DebXI9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q96G46 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-5458011|uniprotkb:Q96HM5|uniprotkb:Q9BSU4|uniprotkb:Q9H877|uniprotkb:Q9NPR1|ensembl:ENSP00000311977 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:dus3l_human(display_long)|uniprotkb:DUS3L(gene name)|psi-mi:DUS3L(display_short)|uniprotkb:tRNA-dihydrouridine synthase 3-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_001155091.1|refseq:NP_064560.2|ensembl:ENSG00000141994(gene)|ensembl:ENST00000309061(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0017150"(tRNA dihydrouridine synthase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018517|interpro:IPR035587|interpro:IPR041367 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:WI70F8sJXWiIGEEuz+VUhZ3IjJs9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q02413 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:Q9Y6H1 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:O95400 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-768015|uniprotkb:Q9ULP2|uniprotkb:B2RDX2|ensembl:ENSP00000304903|ensembl:ENSP00000456935 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:cd2b2_human(display_long)|uniprotkb:CD2BP2(gene name)|psi-mi:CD2BP2(display_short)|uniprotkb:KIAA1178(gene name synonym)|uniprotkb:U5 snRNP 52K protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) refseq:NP_001230575.1|refseq:NP_006101.1|ensembl:ENSG00000169217(gene)|ensembl:ENST00000305596(transcript)|ensembl:ENST00000569466(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR003169(GYF)|interpro:IPR035445|interpro:IPR039905|mint:O95400|rcsb pdb:1GYF|rcsb pdb:1L2Z|rcsb pdb:1SYX|rcsb pdb:4BWS|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:eE6hXTyt05DhzzofcS/QJmUsLEY9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:P31944 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:P25311 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-2513837|ensembl:ENSP00000292401|uniprotkb:Q5XKQ4|uniprotkb:O60386|uniprotkb:Q8N4N0|uniprotkb:D6W5T8 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:za2g_human(display_long)|uniprotkb:AZGP1(gene name)|psi-mi:AZGP1(display_short)|uniprotkb:ZAG(gene name synonym)|uniprotkb:ZNGP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) ensembl:ENSG00000160862(gene)|ensembl:ENST00000292401(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|interpro:IPR036179|interpro:IPR037055|mint:P25311|rcsb pdb:1T7V|rcsb pdb:1T7W|rcsb pdb:1T7X|rcsb pdb:1T7Y|rcsb pdb:1T7Z|rcsb pdb:1T80|rcsb pdb:1ZAG|rcsb pdb:3ES6|rcsb pdb:6R2U|reactome:R-HSA-5223345|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001176.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:3Fp6qALNiZRqsI8Kh2lTQ9IMYek9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TER5-1 uniprotkb:O15085 intact:EBI-25399492|ensembl:ENSP00000298694 intact:EBI-311099|intact:EBI-28988539|ensembl:ENSP00000354644|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2 psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410884|imex:IM-26436-176 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_055599.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_937879.1|ensembl:ENSP00000354644|ensembl:ENST00000368194|ensembl:ENSP00000357177|dip:DIP-31622N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rigid:yyNm4orNHbfqAozaQ6ywwNWoymY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IWW6-4 uniprotkb:Q9UDY2 intact:EBI-11959591|ensembl:ENSP00000379448 intact:EBI-1042602|uniprotkb:Q15883|uniprotkb:Q5VXL0|uniprotkb:Q8N756|uniprotkb:Q8NI14|uniprotkb:Q99839|uniprotkb:Q9UDY0|uniprotkb:Q9UDY1|uniprotkb:A2A3H9|uniprotkb:Q5VXL1|intact:EBI-10989219|ensembl:ENSP00000366453|uniprotkb:B7Z2R8|uniprotkb:B7Z7T6|uniprotkb:F5H301|uniprotkb:F5H886 psi-mi:q8iww6-4(display_long)|uniprotkb:ARHGAP12(gene name)|psi-mi:ARHGAP12(display_short)|uniprotkb:Rho-type GTPase-activating protein 12(gene name synonym) psi-mi:zo2_human(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:X104(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)|uniprotkb:ZO2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410934|imex:IM-26436-318 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165322(gene)|ensembl:ENST00000396144(transcript)|intact:EBI-6381010(isoform-parent)|uniprotkb:Q8IWW6-4(isoform-parent) refseq:NP_001163886.1|refseq:NP_001163887.1|refseq:NP_004808.2|refseq:XP_011517508.1|refseq:XP_011517509.1|refseq:XP_011517510.1|refseq:XP_011517511.1|ensembl:ENSG00000119139(gene)|ensembl:ENST00000377245(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035598|interpro:IPR036028|interpro:IPR036034|mint:Q9UDY2|rcsb pdb:2OSG|rcsb pdb:3E17|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gPEtrzcp046iKT9dxFn+llTr2KA9606 rogid:iN/EF8QWKtekoj5eON764eKAdpg9606 rigid:9EtZ3RnNJMSg3k4zGaGytlPny54 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IWW6-4 uniprotkb:Q15637 intact:EBI-11959591|ensembl:ENSP00000379448 intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607 psi-mi:q8iww6-4(display_long)|uniprotkb:ARHGAP12(gene name)|psi-mi:ARHGAP12(display_short)|uniprotkb:Rho-type GTPase-activating protein 12(gene name synonym) psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410934|imex:IM-26436-318 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165322(gene)|ensembl:ENST00000396144(transcript)|intact:EBI-6381010(isoform-parent)|uniprotkb:Q8IWW6-4(isoform-parent) refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gPEtrzcp046iKT9dxFn+llTr2KA9606 rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606 rigid:9EtZ3RnNJMSg3k4zGaGytlPny54 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IWW6-4 uniprotkb:Q7L576 intact:EBI-11959591|ensembl:ENSP00000379448 intact:EBI-1048143|uniprotkb:Q14467|uniprotkb:Q5IED0|uniprotkb:Q6ZSX1|uniprotkb:Q9BSD9|uniprotkb:Q9BVC7|uniprotkb:A8K6D9|ensembl:ENSP00000478779|ensembl:ENSP00000481038|ensembl:ENSP00000499947|ensembl:ENSP00000500331 psi-mi:q8iww6-4(display_long)|uniprotkb:ARHGAP12(gene name)|psi-mi:ARHGAP12(display_short)|uniprotkb:Rho-type GTPase-activating protein 12(gene name synonym) psi-mi:cyfp1_human(display_long)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)|uniprotkb:p140sra-1(gene name synonym)|uniprotkb:CYFIP1(gene name)|psi-mi:CYFIP1(display_short)|uniprotkb:KIAA0068(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410934|imex:IM-26436-318 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165322(gene)|ensembl:ENST00000396144(transcript)|intact:EBI-6381010(isoform-parent)|uniprotkb:Q8IWW6-4(isoform-parent) refseq:NP_001028200.1|refseq:NP_055423.1|refseq:NP_001274739.1|ensembl:ENSG00000273749(gene)|ensembl:ENSG00000288461(gene)|ensembl:ENST00000610365(transcript)|ensembl:ENST00000617928(transcript)|ensembl:ENST00000671714(transcript)|ensembl:ENST00000672091(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031209"(SCAR complex)|go:"GO:0005576"(extracellular region)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032433"(filopodium tip)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0005829"(cytosol)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050890"(cognition)|go:"GO:0051015"(actin filament binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090724"(central region of growth cone)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097484"(dendrite extension)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7L576|rcsb pdb:3P8C|rcsb pdb:4N78|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001311049.1|refseq:NP_001311052.1|dip:DIP-38873N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gPEtrzcp046iKT9dxFn+llTr2KA9606 rogid:cEF+RA9JRXz8Mbsl/s89Up2ONRc9606 rigid:9EtZ3RnNJMSg3k4zGaGytlPny54 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IWW6-4 uniprotkb:O43150 intact:EBI-11959591|ensembl:ENSP00000379448 intact:EBI-310968|uniprotkb:D6W4Y8|ensembl:ENSP00000281419 psi-mi:q8iww6-4(display_long)|uniprotkb:ARHGAP12(gene name)|psi-mi:ARHGAP12(display_short)|uniprotkb:Rho-type GTPase-activating protein 12(gene name synonym) psi-mi:asap2_human(display_long)|uniprotkb:ASAP2(gene name)|psi-mi:ASAP2(display_short)|uniprotkb:KIAA0400(gene name synonym)|uniprotkb:Pyk2 C-terminus-associated protein(gene name synonym)|uniprotkb:Paxillin-associated protein with ARF GAP activity 3(gene name synonym)|uniprotkb:DDEF2(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410934|imex:IM-26436-318 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165322(gene)|ensembl:ENST00000396144(transcript)|intact:EBI-6381010(isoform-parent)|uniprotkb:Q8IWW6-4(isoform-parent) ensembl:ENSP00000281419|ensembl:ENST00000315273|ensembl:ENSP00000316404|refseq:NP_001128663.1|refseq:NP_003878.1|ensembl:ENSG00000151693(gene)|ensembl:ENST00000281419(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR035677|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR038508|interpro:IPR043593|mint:O43150 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gPEtrzcp046iKT9dxFn+llTr2KA9606 rogid:Ye0xTNuPq3d3/1y/2mIFYH9ecNs9606 rigid:9EtZ3RnNJMSg3k4zGaGytlPny54 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IWW6-4 uniprotkb:Q9ULH1 intact:EBI-11959591|ensembl:ENSP00000379448 intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900 psi-mi:q8iww6-4(display_long)|uniprotkb:ARHGAP12(gene name)|psi-mi:ARHGAP12(display_short)|uniprotkb:Rho-type GTPase-activating protein 12(gene name synonym) psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410934|imex:IM-26436-318 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165322(gene)|ensembl:ENST00000396144(transcript)|intact:EBI-6381010(isoform-parent)|uniprotkb:Q8IWW6-4(isoform-parent) refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gPEtrzcp046iKT9dxFn+llTr2KA9606 rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606 rigid:9EtZ3RnNJMSg3k4zGaGytlPny54 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:Q9NWW5 intact:EBI-25410958 intact:EBI-6165897|ensembl:ENSP00000249806|uniprotkb:B4DDH6|uniprotkb:A8K560|uniprotkb:Q6IAB1|uniprotkb:Q96SR0 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:cln6_human(display_long)|uniprotkb:CLN6(gene name)|psi-mi:CLN6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) ensembl:ENSG00000128973(gene)|ensembl:ENST00000249806(transcript)|go:"GO:0001573"(ganglioside metabolic process)|go:"GO:0005730"(nucleolus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007601"(visual perception)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044265"(cellular macromolecule catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0120146"(sulfatide binding)|interpro:IPR029255|refseq:NP_060352.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:oX9lqo/LjQbBWTpBj1voRRmnOO89606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:O14980 intact:EBI-25410958 intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:P04350 intact:EBI-25410958 intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:Q13148 intact:EBI-25410958 intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:Q9UHX1 intact:EBI-25410958 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:O43242 intact:EBI-25410958 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:Q9Y3T9 intact:EBI-25410958 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:Q9Y3D9 intact:EBI-25410958 intact:EBI-1054270|uniprotkb:Q96Q24|uniprotkb:Q9BWH8|uniprotkb:Q9P053|uniprotkb:B2R6V3|ensembl:ENSP00000320184 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:rt23_human(display_long)|uniprotkb:MRPS23(gene name)|psi-mi:MRPS23(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS23(gene name synonym)|uniprotkb:CGI-138(orf name)|uniprotkb:HSPC329(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) refseq:NP_057154.2|ensembl:ENSG00000181610(gene)|ensembl:ENST00000313608(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0031965"(nuclear membrane)|interpro:IPR019520|interpro:IPR023611|mint:Q9Y3D9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:6Iyu6KkT1Y0+n0LKWy5Gf0DkhHw9606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:O75477 intact:EBI-25410958 intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:P53618 intact:EBI-25410958 intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:O60583 intact:EBI-25410958 intact:EBI-2836757|uniprotkb:Q5I1Y0|uniprotkb:A8KA48|uniprotkb:Q29R66|uniprotkb:Q53SR4|uniprotkb:O60582|uniprotkb:D3DP73|uniprotkb:D3DP74|ensembl:ENSP00000264157 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:ccnt2_human(display_long)|uniprotkb:CCNT2(gene name)|psi-mi:CCNT2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) refseq:NP_001232.1|refseq:NP_490595.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019085"(early viral transcription)|go:"GO:0019086"(late viral transcription)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0097322"(7SK snRNA binding)|ensembl:ENSG00000082258(gene)|ensembl:ENST00000264157(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR028862|interpro:IPR036915|interpro:IPR043198|mint:O60583|rcsb pdb:2IVX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|interpro:IPR013763(Cyclin-related) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:v1mUPCNA+Plg8UioUhIj1LL52fI9606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:P31944 intact:EBI-25410958 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07139-1 uniprotkb:P28288 intact:EBI-25410958 intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46 psi-mi:q071391(display_long)|uniprotkb:Ect2(gene name)|psi-mi:Ect2(display_short)|uniprotkb:mKIAA4037(gene name synonym) psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410964|imex:IM-26436-228 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07139-1(isoform-parent) ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:aa5iErwHhP9h9DLarQNA0oFBTMQ10090 rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606 rigid:ZYufIAQocXAeAgRu7Sr60IUHXmI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888 uniprotkb:Q8N1I0-3 intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532 intact:EBI-21557617 psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym) psi-mi:q8n1i03(display_long)|uniprotkb:DOCK4(gene name)|psi-mi:DOCK4(display_short)|uniprotkb:KIAA0716(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25410950|imex:IM-26436-226 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000076928(gene)|ensembl:ENST00000354532(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A uniprotkb:Q8N1I0-3(isoform-parent) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606 rogid:gGBcAqhJmoeDDtSXxJQEqqJM2D49606 rigid:e+a4P0FcgJ3pQVo0vC5/68oks04 false - tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:P34897 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q6S8J3 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-4289913|uniprotkb:Q6S8J4|uniprotkb:Q6S8J8|uniprotkb:Q6S8J5|ensembl:ENSP00000439189|ensembl:ENSP00000507284 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:potee_human(display_long)|uniprotkb:POTEE(gene name)|psi-mi:POTEE(display_short)|uniprotkb:A26C1A(gene name synonym)|uniprotkb:POTE2(gene name synonym)|uniprotkb:ANKRD26-like family C member 1A(gene name synonym)|uniprotkb:Prostate, ovary, testis-expressed protein on chromosome 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 ensembl:ENSG00000188219(gene)|ensembl:ENST00000356920(transcript)|ensembl:ENST00000683005(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129|reactome:R-HSA-9035034|interpro:IPR020902|refseq:NP_001077007.1|refseq:XP_016859650.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:LMuv4bmAG2/uPyH5LR9q+ickvWI9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q8TF74 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-2850112|uniprotkb:Q8TE44|uniprotkb:A8K0L3|uniprotkb:Q658J8|uniprotkb:Q71RE1|ensembl:ENSP00000320924|ensembl:ENSP00000462350|ensembl:ENSP00000462826 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:wipf2_human(display_long)|uniprotkb:WIPF2(gene name)|psi-mi:WIPF2(display_short)|uniprotkb:WICH(gene name synonym)|uniprotkb:WIRE(gene name synonym)|uniprotkb:WASP-interacting protein-related protein(gene name synonym)|uniprotkb:WIP- and CR16-homologous protein(gene name synonym)|uniprotkb:WIP-related protein(gene name synonym)|uniprotkb:PP10631(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 ensembl:ENSP00000320924|ensembl:ENSP00000462350|ensembl:ENSP00000462826|refseq:XP_011522715.1|refseq:NP_573571.1|refseq:XP_005257140.1|refseq:XP_005257141.1|ensembl:ENSG00000171475(gene)|ensembl:ENST00000323571(transcript)|ensembl:ENST00000583130(transcript)|ensembl:ENST00000585043(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0030048"(actin filament-based movement)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028294|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:xnXvZLySNsfyWjL2lkAMUH16hlU9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q9NXA8 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-6556144|uniprotkb:B4DFM4|uniprotkb:B4DYJ5|uniprotkb:F5H5Z9|uniprotkb:Q5T294|uniprotkb:Q5T295|uniprotkb:Q9Y6E6|ensembl:ENSP00000380509|ensembl:ENSP00000476228|ensembl:ENSP00000505086|ensembl:ENSP00000505496 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:sir5_human(display_long)|uniprotkb:SIRT5(gene name)|psi-mi:SIRT5(display_short)|uniprotkb:SIR2L5(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 5(gene name synonym)|uniprotkb:SIR2-like protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_001180196.1|refseq:NP_001229756.1|refseq:NP_036373.1|refseq:NP_112534.1|refseq:XP_005249025.1|ensembl:ENSG00000124523(gene)|ensembl:ENST00000397350(transcript)|ensembl:ENST00000606117(transcript)|ensembl:ENST00000680151(transcript)|ensembl:ENST00000680432(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010566"(regulation of ketone biosynthetic process)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0036046"(protein demalonylation)|go:"GO:0036047"(peptidyl-lysine demalonylation)|go:"GO:0036048"(protein desuccinylation)|go:"GO:0036049"(peptidyl-lysine desuccinylation)|go:"GO:0036054"(protein-malonyllysine demalonylase activity)|go:"GO:0036055"(protein-succinyllysine desuccinylase activity)|go:"GO:0061697"(protein-glutaryllysine deglutarylase activity)|go:"GO:0061698"(protein deglutarylation)|go:"GO:0070403"(NAD+ binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR027546|interpro:IPR029035|rcsb pdb:2B4Y|rcsb pdb:2NYR|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4G1C|rcsb pdb:4HDA|rcsb pdb:5BWL|rcsb pdb:5XHS|rcsb pdb:6ACE|rcsb pdb:6ACL|rcsb pdb:6ACO|rcsb pdb:6ACP|rcsb pdb:6EQS|rcsb pdb:6LJK|rcsb pdb:6LJM|rcsb pdb:6LJN|reactome:R-HSA-2151201 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:w8a5w8pZghQpNpbgYCsuPIj+Sgo9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q96B97 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q96EV2 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-1210748|uniprotkb:B5MC24|uniprotkb:A4D244|uniprotkb:Q52LF5|uniprotkb:Q75LN9|uniprotkb:Q75ML5|uniprotkb:Q9NSV0|ensembl:ENSP00000384160 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:rbm33_human(display_long)|uniprotkb:RBM33(gene name)|psi-mi:RBM33(display_short)|uniprotkb:PRR8(gene name synonym)|uniprotkb:RNA-binding motif protein 33(gene name synonym)|uniprotkb:Proline-rich protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_444271.2|ensembl:ENST00000287912|ensembl:ENSP00000287912|ensembl:ENSP00000384160|ensembl:ENSG00000184863(gene)|ensembl:ENST00000401878(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR039878 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:b+J1rpxK+YeVvWBkCUPaaQBdCUo9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:P48634 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-347545|uniprotkb:Q05BK4|uniprotkb:Q4LE37|uniprotkb:Q8MGQ9|uniprotkb:O95875|uniprotkb:Q5SQ29|uniprotkb:Q5SQ30|uniprotkb:Q5ST84|uniprotkb:Q5STX6|uniprotkb:Q5STX7|uniprotkb:Q68DW9|uniprotkb:Q6P9P7|uniprotkb:Q6PIN1|uniprotkb:Q96QC6|uniprotkb:B0UZL3|uniprotkb:B0UZE9|uniprotkb:B0UX77|ensembl:ENSP00000365175|ensembl:ENSP00000365201|ensembl:ENSP00000372947|ensembl:ENSP00000372956|ensembl:ENSP00000387477|ensembl:ENSP00000387910|ensembl:ENSP00000396812|ensembl:ENSP00000400540|ensembl:ENSP00000404619|ensembl:ENSP00000408226|ensembl:ENSP00000409444|ensembl:ENSP00000413977|ensembl:ENSP00000415182|ensembl:ENSP00000415363 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:prc2a_human(display_long)|uniprotkb:HLA-B-associated transcript 2(gene name synonym)|uniprotkb:PRRC2A(gene name)|psi-mi:PRRC2A(display_short)|uniprotkb:G2(gene name synonym)|uniprotkb:Protein G2(gene name synonym)|uniprotkb:BAT2(gene name synonym)|uniprotkb:Large proline-rich protein BAT2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_542417.2|refseq:NP_004629.3|ensembl:ENSP00000372956|ensembl:ENSP00000404619|ensembl:ENSP00000415182|ensembl:ENSP00000415363|ensembl:ENSP00000387910|ensembl:ENSP00000413977|ensembl:ENSP00000408226|ensembl:ENSP00000409444|ensembl:ENSP00000400540|ensembl:ENSP00000387477|ensembl:ENSP00000396812|ensembl:ENSP00000365175|ensembl:ENSP00000365201|ensembl:ENSP00000372947|ensembl:ENSG00000204469(gene)|ensembl:ENSG00000206427(gene)|ensembl:ENSG00000225164(gene)|ensembl:ENSG00000225748(gene)|ensembl:ENSG00000226618(gene)|ensembl:ENSG00000231370(gene)|ensembl:ENSG00000231825(gene)|ensembl:ENST00000376007(transcript)|ensembl:ENST00000376033(transcript)|ensembl:ENST00000383455(transcript)|ensembl:ENST00000383464(transcript)|ensembl:ENST00000414956(transcript)|ensembl:ENST00000416335(transcript)|ensembl:ENST00000422962(transcript)|ensembl:ENST00000428775(transcript)|ensembl:ENST00000430737(transcript)|ensembl:ENST00000432252(transcript)|ensembl:ENST00000435971(transcript)|ensembl:ENST00000439762(transcript)|ensembl:ENST00000454306(transcript)|ensembl:ENST00000458561(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:P48634 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:6XZhA7FHJ4ckoWPf1yI/OnaNwjo9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q13162 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:P56181 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:P51970 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-1237250|uniprotkb:B1AM93|uniprotkb:Q9Y6N0|ensembl:ENSP00000362873 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:ndua8_human(display_long)|uniprotkb:NDUFA8(gene name)|psi-mi:NDUFA8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 19 kDa subunit(gene name synonym)|uniprotkb:Complex I-19kD(gene name synonym)|uniprotkb:Complex I-PGIV(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_055037.1|ensembl:ENSG00000119421(gene)|ensembl:ENST00000373768(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR010625(CHCH)|interpro:IPR016680("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8")|mint:P51970|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:buGk0RR4rNyaFDdsjenBqzYzlMs9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q8NFP9 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-723014|uniprotkb:B7Z2H9|uniprotkb:Q9HCM8|uniprotkb:Q9NSU1|uniprotkb:Q9NW98|uniprotkb:Q9Y6J1|ensembl:ENSP00000383295|uniprotkb:Q5T320 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:nbea_human(display_long)|uniprotkb:Lysosomal-trafficking regulator 2(gene name synonym)|uniprotkb:Protein BCL8B(gene name synonym)|uniprotkb:NBEA(gene name)|psi-mi:NBEA(display_short)|uniprotkb:BCL8B(gene name synonym)|uniprotkb:KIAA1544(gene name synonym)|uniprotkb:LYST2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_056493.3|refseq:NP_001191126.1|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR010508(Protein of unknown function DUF1088)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|rcsb pdb:1MI1|reactome:R-HSA-112314|reactome:R-HSA-163615|reactome:R-HSA-2122947|reactome:R-HSA-9609736|ensembl:ENSG00000172915(gene)|ensembl:ENST00000400445(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:gfO4KOqPksy4F827O5y71CM6zPU9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q96EL3 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-2513715|ensembl:ENSP00000258105 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:rm53_human(display_long)|uniprotkb:MRPL53(gene name)|psi-mi:MRPL53(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 ensembl:ENSG00000204822(gene)|ensembl:ENST00000258105(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR019716|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7A5J|refseq:NP_444278.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:+P6xCKwzJVVQv/StyLhlLH9NkgA9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q8N983 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-1043145|ensembl:ENSP00000315364|uniprotkb:Q5JW06|uniprotkb:Q7Z719|uniprotkb:Q7Z7H6|uniprotkb:Q86XN1|uniprotkb:Q9BYC7|uniprotkb:B1AL09|uniprotkb:B1AL07|uniprotkb:B1AL10|intact:EBI-1047104|uniprotkb:D3DR71|uniprotkb:B1AL06|uniprotkb:C9J5Q3 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:rm43_human(display_long)|uniprotkb:Mitochondrial ribosomal protein bMRP36a(gene name synonym)|uniprotkb:MRPL43(gene name)|psi-mi:MRPL43(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL43(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|ensembl:ENSG00000055950(gene)|ensembl:ENST00000318325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR039927|mint:Q8N983|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:7A5I|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|refseq:NP_789764.1|refseq:XP_006718098.1|refseq:NP_115488.2|refseq:NP_789762.1|refseq:NP_789763.1|refseq:NP_001295325.1|ensembl:ENST00000299179|ensembl:ENSP00000299179|ensembl:ENSP00000315364|ensembl:ENST00000318364|ensembl:ENSP00000315948|ensembl:ENST00000342071|ensembl:ENSP00000339844|ensembl:ENST00000370234|ensembl:ENSP00000359254|ensembl:ENST00000370236|ensembl:ENSP00000359256|ensembl:ENST00000370242|ensembl:ENSP00000359262|refseq:XP_005270288.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:p3wPkljBAhx4IwvXsvfXDaEvpag9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q6P1L8 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-1043903|ensembl:ENSP00000361084|uniprotkb:Q96Q72|uniprotkb:B2R575 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:rm14_human(display_long)|uniprotkb:MRPL14(gene name)|psi-mi:MRPL14(display_short)|uniprotkb:RPML32(gene name synonym)|uniprotkb:MRPL32(gene name synonym)|uniprotkb:39S ribosomal protein L32, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein uL14m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 ensembl:ENSG00000180992(gene)|ensembl:ENST00000372014(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR036853|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_115487.2|refseq:NP_001305696.1|refseq:NP_001305697.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:Iwh7qhYEwAsJk6e9hA2IiCcvey09606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:P61604 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:C9JLW8 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-11599148|uniprotkb:Q6ZUL0|ensembl:ENSP00000409009|ensembl:ENSP00000445543|ensembl:ENSP00000458707|ensembl:ENSP00000458720|ensembl:ENSP00000499966|ensembl:ENSP00000500382|ensembl:ENSP00000500493|ensembl:ENSP00000500656 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:mcri1_human(display_long)|uniprotkb:MCRIP1(gene name)|psi-mi:MCRIP1(display_short)|uniprotkb:FAM195B(gene name synonym)|uniprotkb:GRAN2(gene name synonym)|uniprotkb:Granulin-2(gene name synonym)|uniprotkb:Protein FAM195B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_001087236.1|refseq:NP_997251.2|ensembl:ENST00000673154(transcript)|ensembl:ENST00000673369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|interpro:IPR029428|mint:C9JLW8|ensembl:ENSG00000225663(gene)|ensembl:ENSG00000288213(gene)|ensembl:ENST00000455127(transcript)|ensembl:ENST00000538396(transcript)|ensembl:ENST00000574190(transcript)|ensembl:ENST00000576730(transcript)|ensembl:ENST00000672201(transcript)|ensembl:ENST00000672501(transcript) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:iZOqcqhEDT2q90EsGR+8S8Oef809606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q8N8S7 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-2834410|uniprotkb:Q5VTQ9|uniprotkb:Q9UFB8|uniprotkb:Q9NVF3|uniprotkb:Q502W5|uniprotkb:Q5T5M7|uniprotkb:Q5VTR0|uniprotkb:D0PQI2|ensembl:ENSP00000355809 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:enah_human(display_long)|uniprotkb:ENAH(gene name)|psi-mi:ENAH(display_short)|uniprotkb:MENA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_001008493.1|refseq:NP_060682.2|ensembl:ENSG00000154380(gene)|ensembl:ENST00000366844(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|mint:Q8N8S7|rcsb pdb:2HO2|rcsb pdb:2IYB|rcsb pdb:2XQN|rcsb pdb:4MY6|rcsb pdb:5N91|rcsb pdb:5N9C|rcsb pdb:5N9P|rcsb pdb:5NAJ|rcsb pdb:5NBF|rcsb pdb:5NBX|go:"GO:0005925"(focal adhesion)|rcsb pdb:5NC2|rcsb pdb:5NC7|rcsb pdb:5NCF|rcsb pdb:5NCG|rcsb pdb:5NCP|rcsb pdb:5ND0|rcsb pdb:5NDU|rcsb pdb:5NEG|rcsb pdb:6RCF|rcsb pdb:6RCJ|rcsb pdb:6RD2|rcsb pdb:6XVT|rcsb pdb:6XXR|rcsb pdb:7A5M|rcsb pdb:7AKI|reactome:R-HSA-202433|reactome:R-HSA-376176 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:FxcMlDgO3bbl9NRD/z+fDOcdLic9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:Q9Y5K6 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:P47755 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-762451|uniprotkb:B4DG50|ensembl:ENSP00000354947 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_006127.1|ensembl:ENSG00000198898(gene)|ensembl:ENST00000361183(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|go:"GO:0016020"(membrane) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:O43684 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_001007794.1|refseq:NP_004716.1|ensembl:ENSG00000154473(gene)|ensembl:ENST00000368865(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|dip:DIP-24205N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:nqzARPql2cThSUpxSb6PuTRn51E9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2QD90 uniprotkb:P48047 intact:EBI-25410996|ensembl:ENSPTRP00000015819 intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299 psi-mi:h2qd90_pantr(display_long)|uniprotkb:ARHGAP27(gene name)|psi-mi:ARHGAP27(display_short) psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9598(pantr)|taxid:9598("Pan troglodytes (Chimpanzee)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411017|imex:IM-26436-138 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSPTRG00000009304(gene)|ensembl:ENSPTRT00000017092(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015767(Rho GTPase activating)|interpro:IPR036020|interpro:IPR036028|refseq:XP_016787086.1 refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xXsIkLptdUgzkvjVX15B/qN7iqM9598 rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606 rigid:CVEUF5C9iKPC/yTKqwCt93L4uPM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:P82970 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-3951862|uniprotkb:Q5JSL1|ensembl:ENSP00000350848 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:hmgn5_human(display_long)|uniprotkb:HMGN5(gene name)|psi-mi:HMGN5(display_short)|uniprotkb:NSBP1(gene name synonym)|uniprotkb:Nucleosome-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_110390.1|ensembl:ENSG00000198157(gene)|ensembl:ENST00000358130(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|interpro:IPR040164 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:B+ej0KzpeCvCXlJc+6DemTmLGB89606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:Q6RFH5 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-722366|uniprotkb:Q9BRC9|uniprotkb:Q9H6X8|uniprotkb:Q9NVY2|uniprotkb:A8K8G5|ensembl:ENSP00000278856|ensembl:ENSP00000432119|ensembl:ENSP00000435726 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:wdr74_human(display_long)|uniprotkb:NOP seven-associated protein 1(gene name synonym)|uniprotkb:WDR74(gene name)|psi-mi:WDR74(display_short)|uniprotkb:NSA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_060563.2|refseq:XP_005274112.1|refseq:NP_001294906.1|ensembl:ENSG00000133316(gene)|ensembl:ENST00000278856(transcript)|ensembl:ENST00000525239(transcript)|ensembl:ENST00000529106(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037379|mint:Q6RFH5 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:KGh4kcZ85zi1yj6Ow10pW3h7ECM9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:Q86WX3 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-4479407|uniprotkb:B0QY96|uniprotkb:Q5JZA1|ensembl:ENSP00000333948 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:aros_human(display_long)|uniprotkb:RPS19BP1(gene name)|psi-mi:RPS19BP1(display_short)|uniprotkb:AROS(gene name synonym)|uniprotkb:40S ribosomal protein S19-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_919307.1|ensembl:ENSG00000187051(gene)|ensembl:ENST00000334678(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0019899"(enzyme binding)|interpro:IPR023262|mint:Q86WX3|reactome:R-HSA-3371453 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:A2pEtlH5IGyyVVhqX9EvlHE8XTM9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:Q86U42 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:P83916 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:Q5TCZ1 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-2483234|uniprotkb:O43302|uniprotkb:Q5TCZ2|uniprotkb:Q5TDQ8|uniprotkb:D3DR98|ensembl:ENSP00000358789 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:spd2a_human(display_long)|uniprotkb:Tyrosine kinase substrate with five SH3 domains(gene name synonym)|uniprotkb:SH3PXD2A(gene name)|psi-mi:SH3PXD2A(display_short)|uniprotkb:FISH(gene name synonym)|uniprotkb:KIAA0418(gene name synonym)|uniprotkb:SH3MD1(gene name synonym)|uniprotkb:SH3 multiple domains protein 1(gene name synonym)|uniprotkb:Five SH3 domain-containing protein(gene name synonym)|uniprotkb:Adapter protein TKS5(gene name synonym)|uniprotkb:TKS5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_055446.2|refseq:XP_005270351.1|ensembl:ENSG00000107957(gene)|ensembl:ENST00000369774(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0030054"(cell junction)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042995"(cell projection)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0072675"(osteoclast fusion)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR034917|interpro:IPR035449|interpro:IPR035450|interpro:IPR035452|interpro:IPR035453|interpro:IPR035454|interpro:IPR036028|interpro:IPR036871|interpro:IPR037961|rcsb pdb:2DNU|rcsb pdb:2EGA|rcsb pdb:2EGC|rcsb pdb:2EKH|mint:Q5TCZ1|reactome:R-HSA-8941237|reactome:R-HSA-9013148 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:XnTFFWWCeseePTNypWPnbkI+Y6I9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:P51608 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:Q5SSJ5 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-2880687|ensembl:ENSP00000312625|ensembl:ENSP00000403039|uniprotkb:Q5SWC6|uniprotkb:Q6PIM9|uniprotkb:B3KMZ8|uniprotkb:A8K5D7|uniprotkb:Q8NDF0|uniprotkb:Q05BI0|uniprotkb:B4E210|uniprotkb:A6NI71|uniprotkb:Q9UHY0|uniprotkb:Q5SSJ6 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:hp1b3_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short)|uniprotkb:Protein HP1-BP74(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 ensembl:ENSG00000127483(gene)|ensembl:ENST00000312239(transcript)|ensembl:ENST00000438032(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|mint:Q5SSJ5|rcsb pdb:2RQP|go:"GO:0005694"(chromosome)|refseq:XP_016856882.1|refseq:XP_016856883.1|refseq:XP_011539834.1|refseq:XP_011539835.1|refseq:XP_011539836.1|refseq:NP_057371.2|refseq:XP_005245932.1|refseq:XP_005245933.1|refseq:XP_005245934.1|refseq:XP_005245935.1|refseq:XP_005245936.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:kLFithZZv+Qn9YLElEnX81awKDw9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:Q9NSI2 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-5457304|ensembl:ENSP00000291634 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:slx9_human(display_long)|uniprotkb:SLX9(gene name)|psi-mi:SLX9(display_short)|uniprotkb:C21orf70(gene name synonym)|uniprotkb:FAM207A(gene name synonym)|uniprotkb:PRED56(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_001303912.1|refseq:NP_001303913.1|refseq:NP_001303914.1|refseq:NP_001303915.1|refseq:NP_001303917.1|refseq:NP_478070.1|ensembl:ENSG00000160256(gene)|ensembl:ENST00000291634(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR028160 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:pCNahk8BsVfGLtrB/Y290fJCA5g9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:Q96EP5 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-2133162|uniprotkb:Q96MJ3|uniprotkb:Q9NRR9|ensembl:ENSP00000233078 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:dazp1_human(display_long)|uniprotkb:DAZAP1(gene name)|psi-mi:DAZAP1(display_short)|uniprotkb:Deleted in azoospermia-associated protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:NP_061832.2|refseq:NP_733829.1|ensembl:ENSG00000071626(gene)|ensembl:ENST00000233078(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034131|interpro:IPR034134|interpro:IPR035979|mint:Q96EP5|rcsb pdb:2DGS|rcsb pdb:2DH8 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:4uZCZTXZGnZAD9tBcurmc8RhGwY9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98174 uniprotkb:Q9P013 intact:EBI-11038719|uniprotkb:Q8N4D9|uniprotkb:Q5H999|ensembl:ENSP00000364277 intact:EBI-2371709|uniprotkb:B2RC17|uniprotkb:Q05BV9|uniprotkb:Q05DM1|uniprotkb:Q9UI29|ensembl:ENSP00000475615 psi-mi:fgd1_human(display_long)|uniprotkb:FGD1(gene name)|psi-mi:FGD1(display_short)|uniprotkb:FGDY(gene name synonym)|uniprotkb:Faciogenital dysplasia 1 protein(gene name synonym)|uniprotkb:Rho/Rac guanine nucleotide exchange factor FGD1(gene name synonym)|uniprotkb:ZFYVE3(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 3(gene name synonym) psi-mi:cwc15_human(display_long)|uniprotkb:CWC15(gene name)|psi-mi:CWC15(display_short)|uniprotkb:C11orf5(gene name synonym)|uniprotkb:AD-002(orf name)|uniprotkb:HSPC148(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411065|imex:IM-26436-262 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004454.2|ensembl:ENSG00000102302(gene)|ensembl:ENST00000375135(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035939|interpro:IPR035941|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 refseq:XP_011541170.1|refseq:NP_057487.2|refseq:XP_016873405.1|ensembl:ENSG00000150316(gene)|ensembl:ENST00000279839(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006973(Cwf15/Cwc15 cell cycle control protein)|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:VcHOBHkpPWNm6GOGqH7tK9nRoiA9606 rogid:Sq0ehGSKIEKx1X9xv4Nx0ZiqXhk9606 rigid:9zKvHzkuhx5gfHYZvhgyU6FxnJM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9CXP4 uniprotkb:Q9H0D6 intact:EBI-25411093|ensembl:ENSMUSP00000006029|ensembl:ENSMUSP00000130977|ensembl:ENSMUSP00000132008|uniprotkb:Q99JY7 intact:EBI-372110|uniprotkb:Q3L8N4|uniprotkb:Q6KGZ9|uniprotkb:Q9BQL1|uniprotkb:Q9NTW0|uniprotkb:Q9NXS6|uniprotkb:Q9UL53|ensembl:ENSP00000366396 psi-mi:rhg08_mouse(display_long)|uniprotkb:Arhgap8(gene name)|psi-mi:Arhgap8(display_short)|uniprotkb:Rho-type GTPase-activating protein 8(gene name synonym) psi-mi:xrn2_human(display_long)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short)|uniprotkb:DHM1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411118|imex:IM-26436-264 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078954(gene)|ensembl:ENSMUST00000006029(transcript)|ensembl:ENSMUST00000168811(transcript)|ensembl:ENSMUST00000172307(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|refseq:NP_001158099.1|refseq:NP_001158100.1|refseq:NP_001192263.1|refseq:NP_082731.2|refseq:XP_006521533.1|refseq:XP_006521534.1 refseq:NP_036387.2|refseq:NP_001304889.1|ensembl:ENSG00000088930(gene)|ensembl:ENST00000377191(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|mint:Q9H0D6|reactome:R-HSA-390471|reactome:R-HSA-6791226|dip:DIP-31166N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:B1I4jk9J7uLwax+MCHPSzSJVI2w10090 rogid:Ui0NiU+fGe68hK5CYTolkhioQbQ9606 rigid:KvUYBYspSkUAbtdsJx8BZi6fhIk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9CXP4 uniprotkb:Q13769 intact:EBI-25411093|ensembl:ENSMUSP00000006029|ensembl:ENSMUSP00000130977|ensembl:ENSMUSP00000132008|uniprotkb:Q99JY7 intact:EBI-5280316|uniprotkb:O60839|uniprotkb:Q9UPZ5|ensembl:ENSP00000380969|ensembl:ENSP00000380970|ensembl:ENSP00000380971|ensembl:ENSP00000420306 psi-mi:rhg08_mouse(display_long)|uniprotkb:Arhgap8(gene name)|psi-mi:Arhgap8(display_short)|uniprotkb:Rho-type GTPase-activating protein 8(gene name synonym) psi-mi:thoc5_human(display_long)|uniprotkb:THOC5(gene name)|psi-mi:THOC5(display_short)|uniprotkb:C22orf19(gene name synonym)|uniprotkb:KIAA0983(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 79(gene name synonym)|uniprotkb:NF2/meningioma region protein pK1.3(gene name synonym)|uniprotkb:Placental protein 39.2(gene name synonym)|uniprotkb:hTREX90(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411118|imex:IM-26436-264 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078954(gene)|ensembl:ENSMUST00000006029(transcript)|ensembl:ENSMUST00000168811(transcript)|ensembl:ENSMUST00000172307(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|refseq:NP_001158099.1|refseq:NP_001158100.1|refseq:NP_001192263.1|refseq:NP_082731.2|refseq:XP_006521533.1|refseq:XP_006521534.1 refseq:NP_001002877.1|refseq:NP_001002878.1|refseq:NP_001002879.1|refseq:NP_003669.4|ensembl:ENSG00000100296(gene)|ensembl:ENST00000397871(transcript)|ensembl:ENST00000397872(transcript)|ensembl:ENST00000397873(transcript)|ensembl:ENST00000490103(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR019163|mint:Q13769|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:B1I4jk9J7uLwax+MCHPSzSJVI2w10090 rogid:JoeUa2WhtV/dR2HSjUEBAHDZZtw9606 rigid:KvUYBYspSkUAbtdsJx8BZi6fhIk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9CXP4 uniprotkb:Q99962 intact:EBI-25411093|ensembl:ENSMUSP00000006029|ensembl:ENSMUSP00000130977|ensembl:ENSMUSP00000132008|uniprotkb:Q99JY7 intact:EBI-77938|ensembl:ENSP00000369981|uniprotkb:Q9NQK5|uniprotkb:B2R618 psi-mi:rhg08_mouse(display_long)|uniprotkb:Arhgap8(gene name)|psi-mi:Arhgap8(display_short)|uniprotkb:Rho-type GTPase-activating protein 8(gene name synonym) psi-mi:sh3g2_human(display_long)|uniprotkb:SH3GL2(gene name)|psi-mi:SH3GL2(display_short)|uniprotkb:CNSA2(gene name synonym)|uniprotkb:SH3D2A(gene name synonym)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:EEN-B1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411118|imex:IM-26436-264 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078954(gene)|ensembl:ENSMUST00000006029(transcript)|ensembl:ENSMUST00000168811(transcript)|ensembl:ENSMUST00000172307(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|refseq:NP_001158099.1|refseq:NP_001158100.1|refseq:NP_001192263.1|refseq:NP_082731.2|refseq:XP_006521533.1|refseq:XP_006521534.1 go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:Q99962|rcsb pdb:1X03|rcsb pdb:1X04|rcsb pdb:2D4C|rcsb pdb:2DBM|reactome:R-HSA-177504|reactome:R-HSA-182971|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|ensembl:ENSG00000107295(gene)|ensembl:ENST00000380607(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|refseq:NP_003017.1|dip:DIP-30996N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:B1I4jk9J7uLwax+MCHPSzSJVI2w10090 rogid:mAk7M0s5Dd2Qoa/e1rPYvVcV3xs9606 rigid:KvUYBYspSkUAbtdsJx8BZi6fhIk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9CXP4 uniprotkb:Q99961 intact:EBI-25411093|ensembl:ENSMUSP00000006029|ensembl:ENSMUSP00000130977|ensembl:ENSMUSP00000132008|uniprotkb:Q99JY7 intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886 psi-mi:rhg08_mouse(display_long)|uniprotkb:Arhgap8(gene name)|psi-mi:Arhgap8(display_short)|uniprotkb:Rho-type GTPase-activating protein 8(gene name synonym) psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411118|imex:IM-26436-264 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078954(gene)|ensembl:ENSMUST00000006029(transcript)|ensembl:ENSMUST00000168811(transcript)|ensembl:ENSMUST00000172307(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|refseq:NP_001158099.1|refseq:NP_001158100.1|refseq:NP_001192263.1|refseq:NP_082731.2|refseq:XP_006521533.1|refseq:XP_006521534.1 refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360 - - crc64:6E5BE978BC955077 figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:B1I4jk9J7uLwax+MCHPSzSJVI2w10090 rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606 rigid:KvUYBYspSkUAbtdsJx8BZi6fhIk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9CXP4 uniprotkb:P82673 intact:EBI-25411093|ensembl:ENSMUSP00000006029|ensembl:ENSMUSP00000130977|ensembl:ENSMUSP00000132008|uniprotkb:Q99JY7 intact:EBI-2513649|ensembl:ENSP00000081029|uniprotkb:Q6P4C6|uniprotkb:Q7L1M6|uniprotkb:Q9HC14|uniprotkb:Q96AI0|uniprotkb:Q32LZ1|uniprotkb:Q9H044|uniprotkb:Q9P1R5|uniprotkb:Q8NBP4 psi-mi:rhg08_mouse(display_long)|uniprotkb:Arhgap8(gene name)|psi-mi:Arhgap8(display_short)|uniprotkb:Rho-type GTPase-activating protein 8(gene name synonym) psi-mi:rt35_human(display_long)|uniprotkb:MRPS35(gene name)|psi-mi:MRPS35(display_short)|uniprotkb:MRPS28(gene name synonym)|uniprotkb:28S ribosomal protein S28, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS35(gene name synonym)|uniprotkb:HDCMD11P(orf name)|uniprotkb:MDS023(orf name)|uniprotkb:PSEC0213(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411118|imex:IM-26436-264 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000078954(gene)|ensembl:ENSMUST00000006029(transcript)|ensembl:ENSMUST00000168811(transcript)|ensembl:ENSMUST00000172307(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|reactome:R-MMU-8980692|refseq:NP_001158099.1|refseq:NP_001158100.1|refseq:NP_001192263.1|refseq:NP_082731.2|refseq:XP_006521533.1|refseq:XP_006521534.1 ensembl:ENSG00000061794(gene)|ensembl:ENST00000081029(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR019349|interpro:IPR039848|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001177793.1|refseq:NP_068593.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:B1I4jk9J7uLwax+MCHPSzSJVI2w10090 rogid:L7fhBRRkth1ePVbRtuVTvC5zcR09606 rigid:KvUYBYspSkUAbtdsJx8BZi6fhIk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:P23284 intact:EBI-25411134 intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:P22392 intact:EBI-25411134 intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:P48047 intact:EBI-25411134 intact:EBI-355815|uniprotkb:Q5U042|uniprotkb:Q6IBI2|uniprotkb:B2R4E2|ensembl:ENSP00000290299 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:atpo_human(display_long)|uniprotkb:ATP5PO(gene name)|psi-mi:ATP5PO(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:ATP5O(gene name synonym)|uniprotkb:ATPO(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) refseq:NP_001688.1|ensembl:ENSG00000241837(gene)|ensembl:ENST00000290299(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:P48047|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:4lQel+z57OEHJXVWW8ijNyp2h2U9606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:P51665 intact:EBI-25411134 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:Q9UNM6 intact:EBI-25411134 intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:iOxE62MMeGx+aqsrir/LukJqeho9606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:P60900 intact:EBI-25411134 intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:P35520 intact:EBI-25411134 intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:Q9NWU2 intact:EBI-25411134 intact:EBI-1051077|uniprotkb:Q8N5M5|uniprotkb:E1P5I3|ensembl:ENSP00000266069 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:gid8_human(display_long)|uniprotkb:GID8(gene name)|psi-mi:GID8(display_short)|uniprotkb:C20orf11(gene name synonym)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym)|uniprotkb:TWA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) refseq:NP_060366.1|ensembl:ENSG00000101193(gene)|ensembl:ENST00000266069(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9NWU2|rcsb pdb:7NSC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:P0HsK72KT6OPKKw7lVSJ/FiY4CU9606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TCU6-1 uniprotkb:P54886 intact:EBI-25411134 intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44 psi-mi:q8tcu61(display_long)|uniprotkb:PREX1(gene name)|psi-mi:PREX1(display_short)|uniprotkb:KIAA1415(gene name synonym) psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411141|imex:IM-26436-140 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8TCU6-1(isoform-parent) ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EvGaUJMrR5DD53V6bQIpocW1Ako9606 rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606 rigid:f3+aBsnq6OpjbEkxNsXM/hn2vrM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:P49756 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:Q96C36 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-358366|uniprotkb:Q7Z515|uniprotkb:Q9Y5J4|ensembl:ENSP00000342502|uniprotkb:A8K798 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:p5cr2_human(display_long)|uniprotkb:PYCR2(gene name)|psi-mi:PYCR2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_037460.2|ensembl:ENSG00000143811(gene)|ensembl:ENST00000343818(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:Q96C36|rcsb pdb:6LHM|reactome:R-HSA-8964539|refseq:NP_001258610.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:lIjn88RdpxuNpN+fgVPZV2bjubA9606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:P32322 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-848624|uniprotkb:B4DMU0|uniprotkb:Q6FHI4|uniprotkb:Q96DI6|uniprotkb:A6NFM2|uniprotkb:Q9HBQ4|ensembl:ENSP00000328858|ensembl:ENSP00000479793 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:p5cr1_human(display_long)|uniprotkb:PYCR1(gene name)|psi-mi:PYCR1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_008838.2|refseq:XP_011521885.1|refseq:XP_011521886.1|refseq:NP_001269209.1|refseq:NP_001269210.1|refseq:XP_005256438.1|refseq:NP_722546.1|ensembl:ENSG00000183010(gene)|ensembl:ENST00000329875(transcript)|ensembl:ENST00000619204(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:P32322|rcsb pdb:2GER|rcsb pdb:2GR9|rcsb pdb:2GRA|rcsb pdb:2IZZ|rcsb pdb:5UAT|rcsb pdb:5UAU|rcsb pdb:5UAV|rcsb pdb:5UAW|rcsb pdb:5UAX|rcsb pdb:6XOZ|rcsb pdb:6XP0|rcsb pdb:6XP1|rcsb pdb:6XP2|rcsb pdb:6XP3|reactome:R-HSA-8964539 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:+hos1FhDb7QofDBHXEBGlWxv+z09606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:P07478 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-14061700|ensembl:ENSP00000487952|ensembl:ENSP00000488338 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:try2_human(display_long)|uniprotkb:PRSS2(gene name)|psi-mi:PRSS2(display_short)|uniprotkb:TRY2(gene name synonym)|uniprotkb:TRYP2(gene name synonym)|uniprotkb:Anionic trypsinogen(gene name synonym)|uniprotkb:Serine protease 2(gene name synonym)|uniprotkb:Trypsin II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|ensembl:ENSG00000275896(gene)|ensembl:ENSG00000282049(gene)|ensembl:ENST00000539842(transcript)|ensembl:ENST00000632112(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07478|reactome:R-HSA-1442490|reactome:R-HSA-1462054|reactome:R-HSA-1592389|reactome:R-HSA-6798695|reactome:R-HSA-6803157|refseq:NP_002761.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:xP8rgMfzospYU202s9zSfkgHHzM9606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:Q8IWS0 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-1055194|uniprotkb:Q5JRC8|uniprotkb:Q96JK3|uniprotkb:Q9BRU0|uniprotkb:Q5JRC7|uniprotkb:D3DTG3|uniprotkb:A8K230|uniprotkb:E9PC97|uniprotkb:B4E0G4|ensembl:ENSP00000329097|ensembl:ENSP00000359839 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:phf6_human(display_long)|uniprotkb:PHD-like zinc finger protein(gene name synonym)|uniprotkb:PHF6(gene name)|psi-mi:PHF6(display_short)|uniprotkb:KIAA1823(gene name synonym)|uniprotkb:CENP-31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_001015877.1|refseq:NP_115711.2|refseq:NP_115834.1|ensembl:ENSG00000156531(gene)|ensembl:ENST00000332070(transcript)|ensembl:ENST00000370803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015631"(tubulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|mint:Q8IWS0|rcsb pdb:4NN2|rcsb pdb:4R7A|go:"GO:0005730"(nucleolus) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:ZHj/64dPBMmA7GOgpdtHLxeNOu49606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:O43809 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:Q5T749 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-10981970|ensembl:ENSP00000475216 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:kprp_human(display_long)|uniprotkb:KPRP(gene name)|psi-mi:KPRP(display_short)|uniprotkb:C1orf45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_001020402.1|refseq:XP_011507873.1|ensembl:ENSG00000203786(gene)|ensembl:ENST00000606109(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0070062"(extracellular exosome)|mint:Q5T749 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:y5a5hbvzlv8VDmCY169of+RrNKo9606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:P52926 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-912511|uniprotkb:Q1M182|uniprotkb:E7EP85|uniprotkb:E7EWA2|uniprotkb:Q1M185|uniprotkb:Q1M186|uniprotkb:Q1M187|uniprotkb:Q1M188|ensembl:ENSP00000384026 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:hmga2_human(display_long)|uniprotkb:High mobility group AT-hook protein 2(gene name synonym)|uniprotkb:HMGA2(gene name)|psi-mi:HMGA2(display_short)|uniprotkb:HMGIC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_003474.1|refseq:NP_003475.1|refseq:NP_001317119.1|ensembl:ENSG00000149948(gene)|ensembl:ENST00000403681(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003131"(mesodermal-endodermal cell signaling)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009615"(response to virus)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031052"(chromosome breakage)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0035501"(MH1 domain binding)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051301"(cell division)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071864"(positive regulation of cell proliferation in bone marrow)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000685"(positive regulation of cellular response to X-ray)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|reactome:R-HSA-2559584 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:J6xNJMDK/cdxNB9cX7Ey2NIlaUo9606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:Q02413 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:P50750 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:Q9BU76 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZW31-1 uniprotkb:O00213 intact:EBI-25399601|ensembl:ENSP00000341489 intact:EBI-81694|uniprotkb:Q96A93|uniprotkb:A6NH82|uniprotkb:A6NL69|ensembl:ENSP00000477213|uniprotkb:D3DQT2|uniprotkb:B7Z2Y0|uniprotkb:A1E379|uniprotkb:B7Z1J5|uniprotkb:B7Z1J6|uniprotkb:Q7Z324|uniprotkb:V9GYK0|uniprotkb:V9GYT4 psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:apbb1_human(display_long)|uniprotkb:APBB1(gene name)|psi-mi:APBB1(display_short)|uniprotkb:FE65(gene name synonym)|uniprotkb:RIR(gene name synonym)|uniprotkb:Protein Fe65(gene name synonym)|uniprotkb:Amyloid-beta A4 precursor protein-binding family B member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411165|imex:IM-26436-70 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) refseq:NP_001244254.1|refseq:XP_016873130.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0010039"(response to iron ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042734"(presynaptic membrane)|ensembl:ENSG00000166313(gene)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|ensembl:ENST00000609360(transcript)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044304"(main axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|go:"GO:1990761"(growth cone lamellipodium)|go:"GO:1990812"(growth cone filopodium)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR039576|mint:O00213|rcsb pdb:2E45|rcsb pdb:2HO2|rcsb pdb:2IDH|rcsb pdb:2OEI|rcsb pdb:3D8D|rcsb pdb:3D8E|rcsb pdb:3D8F|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:5NQH|reactome:R-HSA-5693565|rcsb pdb:3DXC|refseq:XP_011518342.1|refseq:NP_001244248.1|refseq:NP_001155.1|refseq:NP_663722.1|refseq:NP_001244252.1|refseq:NP_001244255.1|refseq:NP_001244249.1|refseq:NP_001244250.1|dip:DIP-30903N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rogid:3vC/0PYrQRCoZLpyDN1xhXmVsD89606 rigid:Hpe94GSzu71leYFeUsAY1UtyP9Q false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O54834-1 uniprotkb:O75746 intact:EBI-25411195 intact:EBI-1047585|uniprotkb:Q96AM8|intact:EBI-2802067|uniprotkb:B3KR64|ensembl:ENSP00000388658 psi-mi:o548341(display_long)|uniprotkb:Arhgap6(gene name)|psi-mi:Arhgap6(display_short) psi-mi:cmc1_human(display_long)|uniprotkb:SLC25A12(gene name)|psi-mi:SLC25A12(display_short)|uniprotkb:ARALAR1(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411200|imex:IM-26436-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O54834-1(isoform-parent) refseq:NP_003696.2|ensembl:ENSG00000115840(gene)|ensembl:ENST00000422440(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0051592"(response to calcium ion)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:O75746|rcsb pdb:4P5X|rcsb pdb:4P60|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PqBAakAuD48dd2+UeXXq1dZkfgk10090 rogid:NMohxjKtV1fhusocdkdQYZ/ng3I9606 rigid:VZyJwkhFaElQmIsTn1tnb2mgcE4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O54834-1 uniprotkb:P50454 intact:EBI-25411195 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:o548341(display_long)|uniprotkb:Arhgap6(gene name)|psi-mi:Arhgap6(display_short) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411200|imex:IM-26436-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O54834-1(isoform-parent) refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PqBAakAuD48dd2+UeXXq1dZkfgk10090 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 rigid:VZyJwkhFaElQmIsTn1tnb2mgcE4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O54834-1 uniprotkb:P22314 intact:EBI-25411195 intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568 psi-mi:o548341(display_long)|uniprotkb:Arhgap6(gene name)|psi-mi:Arhgap6(display_short) psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411200|imex:IM-26436-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O54834-1(isoform-parent) refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PqBAakAuD48dd2+UeXXq1dZkfgk10090 rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606 rigid:VZyJwkhFaElQmIsTn1tnb2mgcE4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O54834-1 uniprotkb:Q9UI30 intact:EBI-25411195 intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349 psi-mi:o548341(display_long)|uniprotkb:Arhgap6(gene name)|psi-mi:Arhgap6(display_short) psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411200|imex:IM-26436-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O54834-1(isoform-parent) refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PqBAakAuD48dd2+UeXXq1dZkfgk10090 rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606 rigid:VZyJwkhFaElQmIsTn1tnb2mgcE4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O54834-1 uniprotkb:Q9Y5L4 intact:EBI-25411195 intact:EBI-1057344|uniprotkb:P62206|uniprotkb:Q9UHL8|uniprotkb:Q9WTL1|ensembl:ENSP00000215570 psi-mi:o548341(display_long)|uniprotkb:Arhgap6(gene name)|psi-mi:Arhgap6(display_short) psi-mi:tim13_human(display_long)|uniprotkb:TIMM13(gene name)|psi-mi:TIMM13(display_short)|uniprotkb:TIM13B(gene name synonym)|uniprotkb:TIMM13A(gene name synonym)|uniprotkb:TIMM13B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411200|imex:IM-26436-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O54834-1(isoform-parent) refseq:NP_036590.1|ensembl:ENSG00000099800(gene)|ensembl:ENST00000215570(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042719"(mitochondrial intermembrane space protein transporter complex)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|interpro:IPR004217(Zinc finger, Tim10/DDP-type)|interpro:IPR035427|interpro:IPR039238|mint:Q9Y5L4|reactome:R-HSA-1268020 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PqBAakAuD48dd2+UeXXq1dZkfgk10090 rogid:kFNYBvKwUM0JECXq9FjvYv55JAM9606 rigid:VZyJwkhFaElQmIsTn1tnb2mgcE4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O54834-1 uniprotkb:Q04837 intact:EBI-25411195 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:o548341(display_long)|uniprotkb:Arhgap6(gene name)|psi-mi:Arhgap6(display_short) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411200|imex:IM-26436-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O54834-1(isoform-parent) refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PqBAakAuD48dd2+UeXXq1dZkfgk10090 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:VZyJwkhFaElQmIsTn1tnb2mgcE4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O54834-1 uniprotkb:Q9Y2S7 intact:EBI-25411195 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:o548341(display_long)|uniprotkb:Arhgap6(gene name)|psi-mi:Arhgap6(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411200|imex:IM-26436-40 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:O54834-1(isoform-parent) ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:PqBAakAuD48dd2+UeXXq1dZkfgk10090 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:VZyJwkhFaElQmIsTn1tnb2mgcE4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60875 uniprotkb:Q92673 intact:EBI-772191|uniprotkb:E9QNW9|uniprotkb:O09115|uniprotkb:Q3TBI4|uniprotkb:Q3TJ16|uniprotkb:Q8CHE1|uniprotkb:Q923E0|uniprotkb:Q9ESG7|ensembl:ENSMUSP00000029694 intact:EBI-1171329|uniprotkb:Q92856|uniprotkb:B2RNX7|ensembl:ENSP00000260197 psi-mi:arhg2_mouse(display_long)|uniprotkb:Kiaa0651(gene name synonym)|uniprotkb:Lbcl1(gene name synonym)|uniprotkb:Lfc(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor H1(gene name synonym)|uniprotkb:Lymphoid blast crisis-like 1(gene name synonym)|uniprotkb:LBC'S first cousin(gene name synonym)|uniprotkb:Oncogene LFC(gene name synonym)|uniprotkb:Rhobin(gene name synonym)|uniprotkb:Arhgef2(gene name)|psi-mi:Arhgef2(display_short) psi-mi:sorl_human(display_long)|uniprotkb:Sorting protein-related receptor containing LDLR class A repeats(gene name synonym)|uniprotkb:SorLA-1(gene name synonym)|uniprotkb:Low-density lipoprotein receptor relative with 11 ligand-binding repeats(gene name synonym)|uniprotkb:SORL1(gene name)|psi-mi:SORL1(display_short)|uniprotkb:C11orf32(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411220|imex:IM-26436-266 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185840.1|refseq:NP_001185841.1|refseq:NP_001185842.1|refseq:NP_032513.3|refseq:XP_006501130.1|ensembl:ENSMUSG00000028059(gene)|ensembl:ENSMUST00000029694(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045087"(innate immune response)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071802"(negative regulation of podosome assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020|mint:Q60875|rcsb pdb:5WI4|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013026 refseq:NP_003096.1|ensembl:ENSG00000137642(gene)|ensembl:ENST00000260197(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0038020"(insulin receptor recycling)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051604"(protein maturation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902771"(positive regulation of choline O-acetyltransferase activity)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1902955"(positive regulation of early endosome to recycling endosome transport)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902997"(negative regulation of neurofibrillary tangle assembly)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006581(VPS10)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR023415|interpro:IPR031777|interpro:IPR031778|interpro:IPR036055|interpro:IPR036116|mint:Q92673|rcsb pdb:2DM4|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3WSX|rcsb pdb:3WSY|rcsb pdb:3WSZ|reactome:R-HSA-977225|go:"GO:2001137"(positive regulation of endocytic recycling)|dip:DIP-41229N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Le4PMm1AT/ManVpetNT2wBsUlok10090 rogid:JoB0wm+nsEc1vhUsfcaOrc9YwMc9606 rigid:Lflm9fFnTanpLHWUPqqzu3v1SQI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60875 uniprotkb:Q5H9R7 intact:EBI-772191|uniprotkb:E9QNW9|uniprotkb:O09115|uniprotkb:Q3TBI4|uniprotkb:Q3TJ16|uniprotkb:Q8CHE1|uniprotkb:Q923E0|uniprotkb:Q9ESG7|ensembl:ENSMUSP00000029694 intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-28971860|ensembl:ENSP00000377389 psi-mi:arhg2_mouse(display_long)|uniprotkb:Kiaa0651(gene name synonym)|uniprotkb:Lbcl1(gene name synonym)|uniprotkb:Lfc(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor H1(gene name synonym)|uniprotkb:Lymphoid blast crisis-like 1(gene name synonym)|uniprotkb:LBC'S first cousin(gene name synonym)|uniprotkb:Oncogene LFC(gene name synonym)|uniprotkb:Rhobin(gene name synonym)|uniprotkb:Arhgef2(gene name)|psi-mi:Arhgef2(display_short) psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411220|imex:IM-26436-266 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185840.1|refseq:NP_001185841.1|refseq:NP_001185842.1|refseq:NP_032513.3|refseq:XP_006501130.1|ensembl:ENSMUSG00000028059(gene)|ensembl:ENSMUST00000029694(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045087"(innate immune response)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071802"(negative regulation of podosome assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020|mint:Q60875|rcsb pdb:5WI4|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013026 refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|ensembl:ENST00000265636|ensembl:ENSP00000265636|ensembl:ENSP00000377389|ensembl:ENST00000393801|ensembl:ENSP00000377390|ensembl:ENST00000524845|ensembl:ENSP00000431415|ensembl:ENST00000524904|ensembl:ENSP00000433058|ensembl:ENST00000529710|ensembl:ENSP00000437329|refseq:XP_011543442.1|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|ensembl:ENSG00000110075(gene)|ensembl:ENST00000393800(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Le4PMm1AT/ManVpetNT2wBsUlok10090 rogid:9hU14AmzYI9nORfchfMtLoyRecA9606 rigid:Lflm9fFnTanpLHWUPqqzu3v1SQI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60875 uniprotkb:O00743 intact:EBI-772191|uniprotkb:E9QNW9|uniprotkb:O09115|uniprotkb:Q3TBI4|uniprotkb:Q3TJ16|uniprotkb:Q8CHE1|uniprotkb:Q923E0|uniprotkb:Q9ESG7|ensembl:ENSMUSP00000029694 intact:EBI-359751|uniprotkb:Q5U0A2|uniprotkb:Q9UIC9|uniprotkb:B2R5V6|uniprotkb:B7Z5K9|uniprotkb:B7Z2W9|ensembl:ENSP00000362648 psi-mi:arhg2_mouse(display_long)|uniprotkb:Kiaa0651(gene name synonym)|uniprotkb:Lbcl1(gene name synonym)|uniprotkb:Lfc(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor H1(gene name synonym)|uniprotkb:Lymphoid blast crisis-like 1(gene name synonym)|uniprotkb:LBC'S first cousin(gene name synonym)|uniprotkb:Oncogene LFC(gene name synonym)|uniprotkb:Rhobin(gene name synonym)|uniprotkb:Arhgef2(gene name)|psi-mi:Arhgef2(display_short) psi-mi:ppp6_human(display_long)|uniprotkb:PPP6C(gene name)|psi-mi:PPP6C(display_short)|uniprotkb:PPP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411220|imex:IM-26436-266 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185840.1|refseq:NP_001185841.1|refseq:NP_001185842.1|refseq:NP_032513.3|refseq:XP_006501130.1|ensembl:ENSMUSG00000028059(gene)|ensembl:ENSMUST00000029694(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045087"(innate immune response)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071802"(negative regulation of podosome assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020|mint:Q60875|rcsb pdb:5WI4|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013026 refseq:NP_001116827.1|refseq:NP_001116841.1|refseq:NP_002712.1|dip:DIP-27581N|ensembl:ENSG00000119414(gene)|ensembl:ENST00000373547(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:O00743|reactome:R-HSA-171319|reactome:R-HSA-204005 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Le4PMm1AT/ManVpetNT2wBsUlok10090 rogid:IdVJPgcG3d38BpLEPVGIaKqBRVI9606 rigid:Lflm9fFnTanpLHWUPqqzu3v1SQI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60875 uniprotkb:P12532 intact:EBI-772191|uniprotkb:E9QNW9|uniprotkb:O09115|uniprotkb:Q3TBI4|uniprotkb:Q3TJ16|uniprotkb:Q8CHE1|uniprotkb:Q923E0|uniprotkb:Q9ESG7|ensembl:ENSMUSP00000029694 intact:EBI-1050662|uniprotkb:Q0VAM3|uniprotkb:Q32NF6|uniprotkb:Q53FC4|uniprotkb:B4DIT8|uniprotkb:B7ZA09|ensembl:ENSP00000300283|ensembl:ENSP00000406577|ensembl:ENSP00000413165|ensembl:ENSP00000413255 psi-mi:arhg2_mouse(display_long)|uniprotkb:Kiaa0651(gene name synonym)|uniprotkb:Lbcl1(gene name synonym)|uniprotkb:Lfc(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor H1(gene name synonym)|uniprotkb:Lymphoid blast crisis-like 1(gene name synonym)|uniprotkb:LBC'S first cousin(gene name synonym)|uniprotkb:Oncogene LFC(gene name synonym)|uniprotkb:Rhobin(gene name synonym)|uniprotkb:Arhgef2(gene name)|psi-mi:Arhgef2(display_short) psi-mi:kcru_human(display_long)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:CKMT1A(gene name)|psi-mi:CKMT1A(display_short)|uniprotkb:CKMT(gene name synonym)|uniprotkb:CKMT1B(gene name)|psi-mi:CKMT1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411220|imex:IM-26436-266 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185840.1|refseq:NP_001185841.1|refseq:NP_001185842.1|refseq:NP_032513.3|refseq:XP_006501130.1|ensembl:ENSMUSG00000028059(gene)|ensembl:ENSMUST00000029694(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045087"(innate immune response)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071802"(negative regulation of podosome assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020|mint:Q60875|rcsb pdb:5WI4|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013026 refseq:NP_001015001.1|refseq:NP_066270.1|refseq:NP_001308855.1|refseq:NP_001308856.1|refseq:NP_001308857.1|refseq:XP_016877858.1|refseq:XP_016877859.1|refseq:XP_011519496.1|refseq:XP_011519497.1|refseq:XP_011519498.1|refseq:XP_011519499.1|ensembl:ENSG00000223572(gene)|ensembl:ENSG00000237289(gene)|ensembl:ENST00000300283(transcript)|ensembl:ENST00000413453(transcript)|ensembl:ENST00000434505(transcript)|ensembl:ENST00000441322(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12532|rcsb pdb:1QK1|reactome:R-HSA-71288 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Le4PMm1AT/ManVpetNT2wBsUlok10090 rogid:2ZgqE1XmbPXtjVY6lIdy+e0bSdU9606 rigid:Lflm9fFnTanpLHWUPqqzu3v1SQI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q60875 uniprotkb:O15084 intact:EBI-772191|uniprotkb:E9QNW9|uniprotkb:O09115|uniprotkb:Q3TBI4|uniprotkb:Q3TJ16|uniprotkb:Q8CHE1|uniprotkb:Q923E0|uniprotkb:Q9ESG7|ensembl:ENSMUSP00000029694 intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341 psi-mi:arhg2_mouse(display_long)|uniprotkb:Kiaa0651(gene name synonym)|uniprotkb:Lbcl1(gene name synonym)|uniprotkb:Lfc(gene name synonym)|uniprotkb:Guanine nucleotide exchange factor H1(gene name synonym)|uniprotkb:Lymphoid blast crisis-like 1(gene name synonym)|uniprotkb:LBC'S first cousin(gene name synonym)|uniprotkb:Oncogene LFC(gene name synonym)|uniprotkb:Rhobin(gene name synonym)|uniprotkb:Arhgef2(gene name)|psi-mi:Arhgef2(display_short) psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411220|imex:IM-26436-266 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185840.1|refseq:NP_001185841.1|refseq:NP_001185842.1|refseq:NP_032513.3|refseq:XP_006501130.1|ensembl:ENSMUSG00000028059(gene)|ensembl:ENSMUST00000029694(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002102"(podosome)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045087"(innate immune response)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055059"(asymmetric neuroblast division)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071802"(negative regulation of podosome assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037806|interpro:IPR041020|mint:Q60875|rcsb pdb:5WI4|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013026 refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Le4PMm1AT/ManVpetNT2wBsUlok10090 rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606 rigid:Lflm9fFnTanpLHWUPqqzu3v1SQI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:Q8N5M4 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-2851213|uniprotkb:Q8WYY7|ensembl:ENSP00000325266|ensembl:ENSP00000434340 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:ttc9c_human(display_long)|uniprotkb:TTC9C(gene name)|psi-mi:TTC9C(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 refseq:NP_001305745.1|refseq:NP_776171.1|refseq:NP_001305741.1|refseq:NP_001305742.1|refseq:NP_001305743.1|refseq:NP_001305744.1|ensembl:ENSG00000162222(gene)|ensembl:ENST00000316461(transcript)|ensembl:ENST00000532583(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:IazckGbo0Z5cqr/m7hx7Av7BJlU9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:P63208 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:P28066 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:Q99959 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-702235|intact:EBI-2692870|uniprotkb:D3DUW9|uniprotkb:Q99960|uniprotkb:Q4VC01|uniprotkb:B8QFA1|uniprotkb:B8QGS6|uniprotkb:B8QGS7|uniprotkb:A0AV37|ensembl:ENSP00000070846 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:pkp2_human(display_long)|uniprotkb:PKP2(gene name)|psi-mi:PKP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 refseq:NP_004563.2|refseq:NP_001005242.2|ensembl:ENSG00000057294(gene)|ensembl:ENST00000070846(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002159"(desmosome assembly)|go:"GO:0002934"(desmosome organization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007507"(heart development)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:Q99959|rcsb pdb:3TT9|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:kwGWMlk4SDz0xARlBMD1dY9fehQ9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:P07196 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:Q7Z7H8 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-723524|ensembl:ENSP00000324100|uniprotkb:Q96B80|uniprotkb:Q96Q55|uniprotkb:A6NGJ4 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:rm10_human(display_long)|uniprotkb:MRPL8(gene name synonym)|uniprotkb:RPML8(gene name synonym)|uniprotkb:39S ribosomal protein L8, mitochondrial(gene name synonym)|uniprotkb:MRPL10(gene name)|psi-mi:MRPL10(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL10m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 refseq:NP_660298.2|ensembl:ENSG00000159111(gene)|ensembl:ENST00000351111(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR043141|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7A5I|refseq:NP_683685.1|dip:DIP-59717N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:596vwngTyHb2gmaS48VUilgPQtw9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:Q13015 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-6269719|ensembl:ENSP00000357917 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:Q16352 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-366258|uniprotkb:Q9BRC5|uniprotkb:B1AQK0|ensembl:ENSP00000358865 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:ainx_human(display_long)|uniprotkb:INA(gene name)|psi-mi:INA(display_short)|uniprotkb:66 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 5(gene name synonym)|uniprotkb:NEF5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 refseq:NP_116116.1|ensembl:ENSG00000148798(gene)|ensembl:ENST00000369849(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005883"(neurofilament)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027703|interpro:IPR039008|mint:Q16352 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:HXC2d0wajSa0s9r7b4qtpqi3g+s9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:P35221 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q008S8 uniprotkb:Q99653 intact:EBI-20831987|ensembl:ENSP00000356655|ensembl:ENSP00000442307|uniprotkb:B2RUV6|uniprotkb:Q5JWK2|uniprotkb:Q5JWK3|uniprotkb:Q5JWK4 intact:EBI-722721|uniprotkb:Q6FHZ9|uniprotkb:B2R6H9|ensembl:ENSP00000335632 psi-mi:ect2l_human(display_long)|uniprotkb:Lung-specific F-box and DH domain-containing protein(gene name synonym)|uniprotkb:Putative guanine nucleotide exchange factor LFDH(gene name synonym)|uniprotkb:ECT2L(gene name)|psi-mi:ECT2L(display_short)|uniprotkb:C6orf91(gene name synonym)|uniprotkb:LFDH(gene name synonym) psi-mi:chp1_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short)|uniprotkb:CHP(gene name synonym)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411339|imex:IM-26436-178 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000203734(gene)|ensembl:ENST00000367682(transcript)|ensembl:ENST00000541398(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR025592|interpro:IPR035899|interpro:IPR036047|refseq:NP_001071174.1|refseq:NP_001181966.1 refseq:NP_009167.1|ensembl:ENSG00000187446(gene)|ensembl:ENST00000334660(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:2E30|rcsb pdb:7DSV|rcsb pdb:7DSX|reactome:R-HSA-2160916 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YDKekYmoU9EF7F+SHBu+dXbIQkI9606 rogid:6/VeERuA4F0QeWlUj0pN8u0E6hc9606 rigid:qqWlNiU+YzE7kn191zTyIX1Fegg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:P28072 intact:EBI-25411236 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:P06396 intact:EBI-25411236 intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q6UXN9 intact:EBI-25411236 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:P06753 intact:EBI-25411236 intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q96FV9 intact:EBI-25411236 intact:EBI-1765605|uniprotkb:Q15219|uniprotkb:B2RBP6|uniprotkb:Q64I72|uniprotkb:Q64I73|intact:EBI-28984554|ensembl:ENSP00000261600 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:thoc1_human(display_long)|uniprotkb:hTREX84(gene name synonym)|uniprotkb:THOC1(gene name)|psi-mi:THOC1(display_short)|uniprotkb:HPR1(gene name synonym)|uniprotkb:Nuclear matrix protein p84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_005122.2|ensembl:ENSP00000261600|ensembl:ENSG00000079134(gene)|ensembl:ENST00000261600(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008380"(RNA splicing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0048297"(negative regulation of isotype switching to IgA isotypes)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR021861|mint:Q96FV9|rcsb pdb:1WXP|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:D+lk5iFzcmd1bQRa2cx/nUyq4sI9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q15599 intact:EBI-25411236 intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005|intact:EBI-15579694 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:nhrf2_human(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|ensembl:ENSG00000065054(gene)|ensembl:ENST00000424542(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031197|interpro:IPR036034|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|go:"GO:0042802"(identical protein binding)|dip:DIP-29093N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q15637 intact:EBI-25411236 intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q9Y2P8 intact:EBI-25411236 intact:EBI-11026509|uniprotkb:Q9NY00|uniprotkb:Q5VYW9|uniprotkb:Q9P044|uniprotkb:Q9H9D0|uniprotkb:D3DRI2|uniprotkb:Q5VZU1|ensembl:ENSP00000371169 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:rcl1_human(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RNAC(gene name synonym)|uniprotkb:RPC2(gene name synonym)|uniprotkb:RPCL1(gene name synonym)|uniprotkb:RTC2(gene name synonym)|uniprotkb:HSPC338(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_001273628.1|refseq:NP_001273629.1|refseq:NP_001273630.1|refseq:NP_005763.3|refseq:XP_011515975.1|ensembl:ENSG00000120158(gene)|ensembl:ENST00000381750(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|mint:Q9Y2P8|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:XP_016869665.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:8WnLDVPrx4t1eD6h+emL5waEyDY9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:P06454 intact:EBI-25411236 intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q13523 intact:EBI-25411236 intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q8NAV1 intact:EBI-25411236 intact:EBI-715374|uniprotkb:Q96JW1|uniprotkb:Q9BVZ8|ensembl:ENSP00000257181 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:pr38a_human(display_long)|uniprotkb:PRPF38A(gene name)|psi-mi:PRPF38A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_116253.2|ensembl:ENSG00000134748(gene)|ensembl:ENST00000257181(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005037(PRP38)|interpro:IPR024767|mint:Q8NAV1|rcsb pdb:4RZ9|rcsb pdb:4RZA|rcsb pdb:5F5S|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:Cxehw4X82E4XmwydakoLprmkgmQ9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q9Y2D5 intact:EBI-25411236 intact:EBI-1754555|uniprotkb:Q9UG26|uniprotkb:B1ALX9|uniprotkb:B2RTU4|uniprotkb:B3KQ00|uniprotkb:B4DTZ2|uniprotkb:B7ZW07|uniprotkb:B9EJB5 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:akap2_human(display_long)|uniprotkb:AKAP2(gene name)|psi-mi:AKAP2(display_short)|uniprotkb:KIAA0920(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP-KL(gene name synonym)|uniprotkb:PRKA2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_001004065.2|refseq:NP_001130034.1|refseq:NP_001185585.1|refseq:NP_009134.1|refseq:NP_671492.1|interpro:IPR029304 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:xfHb6tD0ToXJPHpl4MlbKczjzSg9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q9H0G5 intact:EBI-25411236 intact:EBI-5464397|uniprotkb:Q6FI71|ensembl:ENSP00000247026 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:nsrp1_human(display_long)|uniprotkb:NSRP1(gene name)|psi-mi:NSRP1(display_short)|uniprotkb:CCDC55(gene name synonym)|uniprotkb:NSRP70(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 55(gene name synonym)|uniprotkb:Nuclear speckle-related protein 70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_115517.1|refseq:NP_001248396.1|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032502"(developmental process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018612|interpro:IPR042816|mint:Q9H0G5|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000126653(gene)|ensembl:ENST00000247026(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:Hp8MjUsGzGZWl+Y/zyzkOxjnLc49606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:P02788 intact:EBI-25411236 intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q86XP3 intact:EBI-25411236 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:P49674 intact:EBI-25411236 intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:evdzz03ba4MFWavN9xRae/Wxwio9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q10570 intact:EBI-25411236 intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q969X6 intact:EBI-25411236 intact:EBI-2602591|ensembl:ENSP00000327179|ensembl:ENSP00000458843|uniprotkb:Q8TF14|uniprotkb:Q96SZ9|uniprotkb:Q96SP0|uniprotkb:Q9BWK6|uniprotkb:Q96SR9|uniprotkb:Q8NCD9|uniprotkb:Q96T13 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:utp4_human(display_long)|uniprotkb:cPERP-E(gene name synonym)|uniprotkb:UTP4(gene name)|psi-mi:UTP4(display_short)|uniprotkb:CIRH1A(gene name synonym)|uniprotkb:Cirhin(gene name synonym)|uniprotkb:KIAA1988(gene name synonym)|uniprotkb:UTP4 small subunit processome component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) ensembl:ENSG00000141076(gene)|ensembl:ENSG00000262788(gene)|ensembl:ENST00000314423(transcript)|ensembl:ENST00000575702(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q969X6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_116219.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:XNix7TJRZR5kji9VA+24FwyTQyE9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P4F7-1 uniprotkb:Q05682 intact:EBI-25411236 intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826 psi-mi:q6p4f71(display_long)|uniprotkb:ARHGAP11A(gene name)|psi-mi:ARHGAP11A(display_short)|uniprotkb:KIAA0013(gene name synonym) psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411243|imex:IM-26436-320 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6P4F7-1(isoform-parent) refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:5K9YW3tGrVM5WjqnIr9ccFAYhkg9606 rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606 rigid:zpurI5dbzCibqfpoKe28TnZwmt0 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14827 uniprotkb:P09012 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 intact:EBI-607085|ensembl:ENSP00000243563 psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:snrpa_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411287|imex:IM-26436-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|ensembl:ENSG00000077312(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034407|interpro:IPR034409|interpro:IPR035979|mint:P09012|rcsb pdb:1AUD|ensembl:ENST00000243563(transcript)|rcsb pdb:1DRZ|rcsb pdb:1DZ5|rcsb pdb:1FHT|rcsb pdb:1M5K|rcsb pdb:1M5O|rcsb pdb:1M5P|rcsb pdb:1M5V|rcsb pdb:1NU4|rcsb pdb:1OIA|rcsb pdb:1SJ3|rcsb pdb:1SJ4|rcsb pdb:1SJF|rcsb pdb:1U6B|rcsb pdb:1URN|rcsb pdb:1VBX|rcsb pdb:1VBY|rcsb pdb:1VBZ|rcsb pdb:1VC0|rcsb pdb:1VC5|rcsb pdb:1VC6|rcsb pdb:1ZZN|rcsb pdb:2A3J|rcsb pdb:2NZ4|rcsb pdb:2OIH|rcsb pdb:2OJ3|rcsb pdb:2U1A|rcsb pdb:3BO2|rcsb pdb:3BO3|rcsb pdb:3BO4|rcsb pdb:3CUL|rcsb pdb:3CUN|rcsb pdb:3EGZ|rcsb pdb:3G8S|rcsb pdb:3G8T|rcsb pdb:3G96|rcsb pdb:3G9C|rcsb pdb:3HHN|rcsb pdb:3IIN|rcsb pdb:3IRW|rcsb pdb:3IWN|rcsb pdb:3K0J|rcsb pdb:3L3C|rcsb pdb:3MUM|rcsb pdb:3MUR|rcsb pdb:3MUT|rcsb pdb:3R1H|rcsb pdb:3R1L|rcsb pdb:3UCU|rcsb pdb:3UCZ|rcsb pdb:3UD3|rcsb pdb:3UD4|rcsb pdb:3MUV|rcsb pdb:3UTR|rcsb pdb:4C4W|rcsb pdb:4PR6|rcsb pdb:4PRF|rcsb pdb:4W90|rcsb pdb:4W92|rcsb pdb:3MXH|rcsb pdb:3P49|rcsb pdb:3PGW|rcsb pdb:4YB1|rcsb pdb:5DDO|rcsb pdb:5DDP|rcsb pdb:5DDQ|rcsb pdb:5DDR|rcsb pdb:5FJ4|rcsb pdb:6LAS|rcsb pdb:6LAU|rcsb pdb:6LAX|rcsb pdb:6LAZ|rcsb pdb:6QX9|rcsb pdb:6SQN|rcsb pdb:6SQQ|rcsb pdb:6SQT|rcsb pdb:6SQV|rcsb pdb:6SR7|rcsb pdb:6XH0|rcsb pdb:6XH1|rcsb pdb:6XH2|rcsb pdb:6XH3|rcsb pdb:7AEP|rcsb pdb:7B0Y|rcsb pdb:7D7V|rcsb pdb:7LHX|reactome:R-HSA-72163|refseq:NP_004587.1|dip:DIP-29407N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rogid:BJ9zdDzOPs9JYgU8lErj/maq0AY9606 rigid:sHSQGw/FULK7ZnuIN2n7/OMJrFw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14827 uniprotkb:Q9Y3A2 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 intact:EBI-2876697|ensembl:ENSP00000362105|uniprotkb:B4DJC6|uniprotkb:Q9BS98|uniprotkb:Q9NS31|uniprotkb:Q5VT93|intact:EBI-2963233|uniprotkb:A8K785|uniprotkb:D3DPT7 psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:utp11_human(display_long)|uniprotkb:HDCMB12P(orf name)|uniprotkb:UTP11(gene name)|psi-mi:UTP11(display_short)|uniprotkb:UTP11-like protein(gene name synonym)|uniprotkb:UTP11L(gene name synonym)|uniprotkb:CGI-94(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411287|imex:IM-26436-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 ensembl:ENSG00000183520(gene)|ensembl:ENST00000373014(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0032040"(small-subunit processome)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR007144(Small-subunit processome, Utp11)|mint:Q9Y3A2|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_057121.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rogid:JTS/jMbRZE3NifB95Nqh0foDUKI9606 rigid:sHSQGw/FULK7ZnuIN2n7/OMJrFw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14827 uniprotkb:Q15428 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 intact:EBI-2462271|uniprotkb:O75245|uniprotkb:B2RBU1|uniprotkb:D6W605|intact:EBI-28985293|ensembl:ENSP00000221494 psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:sf3a2_human(display_long)|uniprotkb:SF3A2(gene name)|psi-mi:SF3A2(display_short)|uniprotkb:SAP62(gene name synonym)|uniprotkb:Spliceosome-associated protein 62(gene name synonym)|uniprotkb:SF3a66(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411287|imex:IM-26436-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_009096.2|ensembl:ENSP00000221494|dip:DIP-42521N|ensembl:ENSG00000104897(gene)|ensembl:ENST00000221494(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR031781|interpro:IPR036236|mint:Q15428|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rogid:ME4xzpqT37HjPl/xy683FS1Vns89606 rigid:sHSQGw/FULK7ZnuIN2n7/OMJrFw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14827 uniprotkb:Q9UHA3 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 intact:EBI-749321|uniprotkb:Q561V8|uniprotkb:Q8N6S8|uniprotkb:Q96B04|uniprotkb:Q96C76|uniprotkb:Q96HJ1|uniprotkb:B2RD72|ensembl:ENSP00000260443 psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:rlp24_human(display_long)|uniprotkb:Ribosomal protein L24-like(gene name synonym)|uniprotkb:RSL24D1(gene name)|psi-mi:RSL24D1(display_short)|uniprotkb:RPL24L(gene name synonym)|uniprotkb:My024(orf name)|uniprotkb:C15orf15(gene name synonym)|uniprotkb:Ribosomal L24 domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411287|imex:IM-26436-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_057388.1|ensembl:ENSG00000137876(gene)|ensembl:ENST00000260443(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006412"(translation)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023438|interpro:IPR023442|interpro:IPR038630|mint:Q9UHA3|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0022625"(cytosolic large ribosomal subunit) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rogid:dP0x5J6G4bPc/7sbV1LIxLNLDn09606 rigid:sHSQGw/FULK7ZnuIN2n7/OMJrFw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14827 uniprotkb:Q9Y314 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 intact:EBI-1051889|uniprotkb:Q96FD2|ensembl:ENSP00000470034 psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:nosip_human(display_long)|uniprotkb:eNOS-interacting protein(gene name synonym)|uniprotkb:NOSIP(gene name)|psi-mi:NOSIP(display_short)|uniprotkb:CGI-25(orf name)|uniprotkb:E3 ubiquitin-protein ligase NOSIP(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NOSIP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411287|imex:IM-26436-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001257889.1|refseq:NP_057037.1|ensembl:ENSG00000142546(gene)|ensembl:ENST00000596358(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016818(Nitric oxide synthase-interacting)|interpro:IPR031790|reactome:R-HSA-203754|refseq:XP_016882340.1|refseq:XP_016882341.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rogid:vC1sjYkWe4QjRlwCJ3C5+EB8PcA9606 rigid:sHSQGw/FULK7ZnuIN2n7/OMJrFw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14827 uniprotkb:Q5JSP0 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 intact:EBI-4403141|uniprotkb:Q4VX84|uniprotkb:Q7Z7D9|uniprotkb:Q8N5G1|uniprotkb:F8W7P2|ensembl:ENSP00000336914|ensembl:ENSP00000364631|ensembl:ENSP00000496819 psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:fgd3_human(display_long)|uniprotkb:FGD3(gene name)|psi-mi:FGD3(display_short)|uniprotkb:ZFYVE5(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411287|imex:IM-26436-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001077005.1|refseq:NP_149077.2|refseq:NP_001273922.1|refseq:XP_016870763.1|ensembl:ENSG00000127084(gene)|ensembl:ENST00000337352(transcript)|ensembl:ENST00000375482(transcript)|ensembl:ENST00000468206(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|rcsb pdb:2COC|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rogid:GPfnTNLHRBnUKhWFeaYG7Z6U5xA9606 rigid:sHSQGw/FULK7ZnuIN2n7/OMJrFw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14827 uniprotkb:P56545 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 intact:EBI-741533|uniprotkb:O43449|uniprotkb:Q5SQP7|uniprotkb:Q69YI3|uniprotkb:Q86SV0|uniprotkb:Q9H2T8|uniprotkb:A8K2X5|ensembl:ENSP00000338615|ensembl:ENSP00000410474|ensembl:ENSP00000434630|ensembl:ENSP00000436285|uniprotkb:D3DRF5|uniprotkb:Q8IY44|intact:EBI-11742664 psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:ctbp2_human(display_long)|uniprotkb:CTBP2(gene name)|psi-mi:CTBP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411287|imex:IM-26436-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001077383.1|refseq:NP_001320.1|refseq:NP_073713.2|refseq:NP_001307943.1|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56545|rcsb pdb:2OME|rcsb pdb:4LCJ|rcsb pdb:6WKW|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-9662360|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|ensembl:ENSG00000175029(gene)|ensembl:ENST00000337195(transcript)|ensembl:ENST00000411419(transcript)|ensembl:ENST00000494626(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000531469(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:XP_011537653.1|refseq:XP_011537655.1|refseq:XP_011537656.1|refseq:XP_011537657.1|refseq:NP_001307941.1|refseq:NP_001307942.1|refseq:XP_005269618.1|refseq:XP_005269621.1|refseq:XP_005269624.1|refseq:XP_005269625.1|refseq:XP_005269626.1|refseq:XP_005269628.1|refseq:XP_005269629.1|refseq:NP_001277143.1|refseq:NP_001277144.1|refseq:XP_006717705.1|refseq:XP_016871245.1|refseq:XP_016871246.1|dip:DIP-42104N|refseq:XP_011537651.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rogid:6sKiqjMRW/ViEvTbQJoaUjgvZtc9606 rigid:sHSQGw/FULK7ZnuIN2n7/OMJrFw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14827 uniprotkb:P33240 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 intact:EBI-711360|uniprotkb:Q5H951|uniprotkb:Q6LA74|uniprotkb:Q8N502|ensembl:ENSP00000362063 psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:cstf2_human(display_long)|uniprotkb:CSTF2(gene name)|psi-mi:CSTF2(display_short)|uniprotkb:CF-1 64 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 64 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411287|imex:IM-26436-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001293138.1|ensembl:ENSG00000101811(gene)|ensembl:ENST00000372972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016604"(nuclear body)|go:"GO:0071920"(cleavage body)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025742|interpro:IPR026896|interpro:IPR033105|interpro:IPR035979|interpro:IPR038192|mint:P33240|rcsb pdb:1P1T|rcsb pdb:2J8P|rcsb pdb:6Q2I|rcsb pdb:6TZE|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001316.1|dip:DIP-36129N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rogid:oZ/4DPJOEWflU05127TEp+ezQi89606 rigid:sHSQGw/FULK7ZnuIN2n7/OMJrFw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:Q6RFH5 intact:EBI-25411309 intact:EBI-722366|uniprotkb:Q9BRC9|uniprotkb:Q9H6X8|uniprotkb:Q9NVY2|uniprotkb:A8K8G5|ensembl:ENSP00000278856|ensembl:ENSP00000432119|ensembl:ENSP00000435726 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:wdr74_human(display_long)|uniprotkb:NOP seven-associated protein 1(gene name synonym)|uniprotkb:WDR74(gene name)|psi-mi:WDR74(display_short)|uniprotkb:NSA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) refseq:NP_060563.2|refseq:XP_005274112.1|refseq:NP_001294906.1|ensembl:ENSG00000133316(gene)|ensembl:ENST00000278856(transcript)|ensembl:ENST00000525239(transcript)|ensembl:ENST00000529106(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037379|mint:Q6RFH5 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:KGh4kcZ85zi1yj6Ow10pW3h7ECM9606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:Q9P270 intact:EBI-25411309 intact:EBI-3959887|uniprotkb:A8K4P1|uniprotkb:Q8N5R3|ensembl:ENSP00000264313 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:slai2_human(display_long)|uniprotkb:SLAIN2(gene name)|psi-mi:SLAIN2(display_short)|uniprotkb:KIAA1458(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) refseq:NP_065897.1|ensembl:ENSG00000109171(gene)|ensembl:ENST00000264313(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR026179|mint:Q9P270|rcsb pdb:3RDV - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:r8OlU6BASEpehSYkbA9b3F3q5go9606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:Q9NW64 intact:EBI-25411309 intact:EBI-2602260|uniprotkb:A6NDM5|uniprotkb:O95607|uniprotkb:B4DLI9|ensembl:ENSP00000199814 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:rbm22_human(display_long)|uniprotkb:RBM22(gene name)|psi-mi:RBM22(display_short)|uniprotkb:ZC3H16(gene name synonym)|uniprotkb:RNA-binding motif protein 22(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 16(gene name synonym)|uniprotkb:199G4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) refseq:NP_060517.1|go:"GO:0035690"|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|rcsb pdb:2YTC|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|ensembl:ENST00000199814(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000086589(gene)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:PjcPER8I/RBxwu3oACO1LHxzKAM9606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:Q8NFH5 intact:EBI-25411309 intact:EBI-9050429|uniprotkb:B4DP57|uniprotkb:B4DYB4|uniprotkb:Q4ZFZ9|uniprotkb:Q53S95|uniprotkb:Q8TDJ1|ensembl:ENSP00000295119 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:nup35_human(display_long)|uniprotkb:Nucleoporin NUP53(gene name synonym)|uniprotkb:NUP35(gene name)|psi-mi:NUP35(display_short)|uniprotkb:MP44(gene name synonym)|uniprotkb:NUP53(gene name synonym)|uniprotkb:35 kDa nucleoporin(gene name synonym)|uniprotkb:Mitotic phosphoprotein 44(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) refseq:XP_006712317.1|refseq:XP_011508878.1|refseq:XP_011508879.1|refseq:NP_001274513.1|refseq:NP_612142.2|refseq:NP_001274514.1|dip:DIP-47308N|ensembl:ENSG00000163002(gene)|ensembl:ENST00000295119(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051028"(mRNA transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|mint:Q8NFH5|rcsb pdb:4LIR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:oFL2V05tM9dYT+fjUiqMLwxZYr89606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:Q15773 intact:EBI-25411309 intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:Q96I24 intact:EBI-25411309 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:P56537 intact:EBI-25411309 intact:EBI-372243|uniprotkb:Q6IBN8|uniprotkb:Q96TD5|uniprotkb:B7ZBG9|ensembl:ENSP00000363559|ensembl:ENSP00000363574|ensembl:ENSP00000502429 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:if6_human(display_long)|uniprotkb:EIF6(gene name)|psi-mi:EIF6(display_short)|uniprotkb:ITGB4BP(gene name synonym)|uniprotkb:OK/SW-cl.27(orf name)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym)|uniprotkb:"B(2)GCN homolog"(gene name synonym)|uniprotkb:EIF3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) refseq:NP_002203.1|refseq:NP_852131.1|refseq:NP_852133.1|refseq:NP_001254739.1|ensembl:ENSG00000242372(gene)|ensembl:ENST00000374436(transcript)|ensembl:ENST00000374450(transcript)|ensembl:ENST00000675032(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6)|mint:P56537|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:A0pOylQptNBlSiBKiZre7INejF49606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:Q99848 intact:EBI-25411309 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NR80-4 uniprotkb:Q1ED39 intact:EBI-25411309 intact:EBI-9977982|uniprotkb:O43328|uniprotkb:Q5FWF3|ensembl:ENSP00000219837 psi-mi:q9nr80-4(display_long)|uniprotkb:APC-stimulated guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:ARHGEF4(gene name)|psi-mi:ARHGEF4(display_short)|uniprotkb:KIAA1112(gene name synonym) psi-mi:knop1_human(display_long)|uniprotkb:KNOP1(gene name)|psi-mi:KNOP1(display_short)|uniprotkb:C16orf88(gene name synonym)|uniprotkb:FAM191A(gene name synonym)|uniprotkb:TSG118(gene name synonym)|uniprotkb:Protein FAM191A(gene name synonym)|uniprotkb:Testis-specific gene 118 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411315|imex:IM-26436-268 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3389984(isoform-parent) refseq:NP_001013009.2|refseq:NP_001335457.1|refseq:NP_001335458.1|refseq:NP_001335459.1|refseq:NP_001335460.1|ensembl:ENSG00000103550(gene)|ensembl:ENST00000219837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|interpro:IPR028124 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:v17aq+CJqBZNKGqQRMQ7ZCPXlHg9606 rogid:DbTowYDo0km0cUlAS8TTL5JIyyQ9606 rigid:eCx6cg5W5nGRzRb0Xgs7m61mEYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92502 uniprotkb:Q9NSB2 intact:EBI-11792291|uniprotkb:A8K6T2|uniprotkb:D3DVT9|uniprotkb:Q5JST0|uniprotkb:Q68DG7|intact:EBI-28984506|ensembl:ENSP00000252336|ensembl:ENSP00000363725 intact:EBI-2372509|uniprotkb:B2RA43|uniprotkb:Q6ISB0|uniprotkb:Q701L6|ensembl:ENSP00000257951 psi-mi:star8_human(display_long)|uniprotkb:STARD8(gene name)|psi-mi:STARD8(display_short)|uniprotkb:DLC3(gene name synonym)|uniprotkb:KIAA0189(gene name synonym)|uniprotkb:Deleted in liver cancer 3 protein(gene name synonym)|uniprotkb:START domain-containing protein 8(gene name synonym)|uniprotkb:START-GAP3(gene name synonym) psi-mi:krt84_human(display_long)|uniprotkb:KRT84(gene name)|psi-mi:KRT84(display_short)|uniprotkb:KRTHB4(gene name synonym)|uniprotkb:Type II hair keratin Hb4(gene name synonym)|uniprotkb:Keratin-84(gene name synonym)|uniprotkb:Type-II keratin Kb24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411365|imex:IM-26436-270 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135975.1|refseq:NP_001135976.1|refseq:NP_055540.2|refseq:XP_011529371.1|ensembl:ENSP00000252336|ensembl:ENSP00000363725|ensembl:ENST00000374599|ensembl:ENSP00000363727|ensembl:ENSG00000130052(gene)|ensembl:ENST00000252336(transcript)|ensembl:ENST00000374597(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023393|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|dip:DIP-60949N refseq:XP_011536637.1|refseq:NP_149034.2|ensembl:ENSG00000161849(gene)|ensembl:ENST00000257951(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0035878"(nail development)|go:"GO:0045095"(keratin filament)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6mTMYwAgbbJ04nk4GmSlub5hPFU9606 rogid:j3FNHjfONdOzxrg2vXRURLaRoHI9606 rigid:cpeTQSmPFZD3ihqqCIXuFquguBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92502 uniprotkb:Q9HDC5 intact:EBI-11792291|uniprotkb:A8K6T2|uniprotkb:D3DVT9|uniprotkb:Q5JST0|uniprotkb:Q68DG7|intact:EBI-28984506|ensembl:ENSP00000252336|ensembl:ENSP00000363725 intact:EBI-465137|ensembl:ENSP00000344488|uniprotkb:B2RTZ0 psi-mi:star8_human(display_long)|uniprotkb:STARD8(gene name)|psi-mi:STARD8(display_short)|uniprotkb:DLC3(gene name synonym)|uniprotkb:KIAA0189(gene name synonym)|uniprotkb:Deleted in liver cancer 3 protein(gene name synonym)|uniprotkb:START domain-containing protein 8(gene name synonym)|uniprotkb:START-GAP3(gene name synonym) psi-mi:jph1_human(display_long)|uniprotkb:JPH1(gene name)|psi-mi:JPH1(display_short)|uniprotkb:JP1(gene name synonym)|uniprotkb:Junctophilin type 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411365|imex:IM-26436-270 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135975.1|refseq:NP_001135976.1|refseq:NP_055540.2|refseq:XP_011529371.1|ensembl:ENSP00000252336|ensembl:ENSP00000363725|ensembl:ENST00000374599|ensembl:ENSP00000363727|ensembl:ENSG00000130052(gene)|ensembl:ENST00000252336(transcript)|ensembl:ENST00000374597(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023393|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|dip:DIP-60949N ensembl:ENSG00000104369(gene)|ensembl:ENST00000342232(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060402"(calcium ion transport into cytosol)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9HDC5|refseq:NP_065698.1|refseq:NP_001304759.1|refseq:XP_005251331.1|refseq:XP_005251332.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6mTMYwAgbbJ04nk4GmSlub5hPFU9606 rogid:bx+PVSZHNt7kqkjWVW/vYc8Iqek9606 rigid:cpeTQSmPFZD3ihqqCIXuFquguBA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15357 uniprotkb:Q8R5G7 intact:EBI-1384248|uniprotkb:Q13577|uniprotkb:Q13578|uniprotkb:B2RTX5|ensembl:ENSP00000298229 intact:EBI-621463|ensembl:ENSMUSP00000035662|uniprotkb:E9QMK7|uniprotkb:Q5DTN4|uniprotkb:Q6NVF1|uniprotkb:Q8R5G6 psi-mi:ship2_human(display_long)|uniprotkb:INPPL1(gene name)|psi-mi:INPPL1(display_short)|uniprotkb:SHIP2(gene name synonym)|uniprotkb:Inositol polyphosphate phosphatase-like protein 1(gene name synonym)|uniprotkb:Protein 51C(gene name synonym)|uniprotkb:SH2 domain-containing inositol 5'-phosphatase 2(gene name synonym) psi-mi:arap3_mouse(display_long)|uniprotkb:Arap3(gene name)|psi-mi:Arap3(display_short)|uniprotkb:Dual specificity Rho- and Arf-GTPase-activating protein 1(gene name synonym)|uniprotkb:Centd3(gene name synonym)|uniprotkb:Centaurin-delta-3(gene name synonym)|uniprotkb:Drag1(gene name synonym)|uniprotkb:Kiaa4097(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411376|imex:IM-26436-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000298229|ensembl:ENST00000538751|ensembl:ENSP00000444619|refseq:NP_001558.3|refseq:XP_011543301.1|dip:DIP-39733N|ensembl:ENSG00000165458(gene)|ensembl:ENST00000298229(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002376"(immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032868"(response to insulin)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0097178"(ruffle assembly)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036691|interpro:IPR036860|mint:O15357|rcsb pdb:2K4P|rcsb pdb:2KSO|rcsb pdb:2MK2|rcsb pdb:3NR8|rcsb pdb:4A9C|rcsb pdb:5OKM|rcsb pdb:5OKN|rcsb pdb:5OKO|rcsb pdb:5OKP|rcsb pdb:6SQU|rcsb pdb:6SRR|reactome:R-HSA-1660499|reactome:R-HSA-1855204|reactome:R-HSA-912526 ensembl:ENSMUSG00000024451(gene)|ensembl:ENSMUST00000042944(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029071|interpro:IPR037278|interpro:IPR037858|interpro:IPR038508|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013423|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|refseq:NP_001192265.1|refseq:NP_631945.2|refseq:XP_006525552.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:FmRJZVZS8n00OVhTEfEo5gxIvG49606 rogid:T6pzqRyYhNTPo62IU2JQcqE0rQk10090 rigid:ut/+z4kUmtJCJvFDG8azcnOO9Iw false - tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:P53999 intact:EBI-25411384 intact:EBI-998260|uniprotkb:Q96L29|ensembl:ENSP00000265073|ensembl:ENSP00000422078|ensembl:ENSP00000422806|ensembl:ENSP00000426850|ensembl:ENSP00000427100 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:tcp4_human(display_long)|uniprotkb:SUB1 homolog(gene name synonym)|uniprotkb:Positive cofactor 4(gene name synonym)|uniprotkb:p14(gene name synonym)|uniprotkb:SUB1(gene name)|psi-mi:SUB1(display_short)|uniprotkb:PC4(gene name synonym)|uniprotkb:RPO2TC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) refseq:XP_011512246.1|ensembl:ENSG00000113387(gene)|ensembl:ENST00000265073(transcript)|ensembl:ENST00000502897(transcript)|ensembl:ENST00000506237(transcript)|ensembl:ENST00000512913(transcript)|ensembl:ENST00000515355(transcript)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003173(Transcriptional coactivator p15)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|mint:P53999|rcsb pdb:1PCF|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:2C62|rcsb pdb:2PHE|rcsb pdb:4USG|go:"GO:0003697"(single-stranded DNA binding)|rcsb pdb:6YCS|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0051053"(negative regulation of DNA metabolic process)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|refseq:NP_006704.3|refseq:XP_016864475.1|refseq:XP_016864476.1|dip:DIP-29044N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:FqBKBuLmQS+idbd68EdKsTCzPg89606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:Q13243 intact:EBI-25411384 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:P60468 intact:EBI-25411384 intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:Q16531 intact:EBI-25411384 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:P00747 intact:EBI-25411384 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:Q8NCE2 intact:EBI-25411384 intact:EBI-5658424|uniprotkb:Q86VK9|uniprotkb:Q6PIZ4|uniprotkb:Q8IYK1|uniprotkb:Q0JU83|uniprotkb:Q9H6C0|uniprotkb:Q6QE21|uniprotkb:Q0JTH5|uniprotkb:Q8TCM7|ensembl:ENSP00000296003 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:mtmre_human(display_long)|uniprotkb:C3orf29(gene name synonym)|uniprotkb:HCV NS5A-transactivated protein 4 splice variant A-binding protein 1(gene name synonym)|uniprotkb:hJumpy(gene name synonym)|uniprotkb:MTMR14(gene name)|psi-mi:MTMR14(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) refseq:NP_001070993.1|refseq:NP_001070994.1|refseq:NP_071930.2|ensembl:ENSG00000163719(gene)|ensembl:ENST00000296003(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016236"(macroautophagy)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR039802|interpro:IPR039803|mint:Q8NCE2|reactome:R-HSA-1632852|reactome:R-HSA-1660499 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:ftagAuEsNaEzJHotTrA3OjWPPN09606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:Q9Y2R9 intact:EBI-25411384 intact:EBI-1054973|uniprotkb:Q53GD6|uniprotkb:B2R9N5|ensembl:ENSP00000245539 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:rt07_human(display_long)|uniprotkb:bMRP-27a(gene name synonym)|uniprotkb:MRPS7(gene name)|psi-mi:MRPS7(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS7m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) refseq:NP_057055.2|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR023798|interpro:IPR036823|mint:Q9Y2R9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125445(gene)|ensembl:ENST00000245539(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:hrz2XVS38Ex1z125QFx/n9oPsys9606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:Q9Y3B7 intact:EBI-25411384 intact:EBI-5453723|ensembl:ENSP00000308897|uniprotkb:A8K219|uniprotkb:Q32P46|uniprotkb:Q96Q73|uniprotkb:A6NLT0 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:rm11_human(display_long)|uniprotkb:MRPL11(gene name)|psi-mi:MRPL11(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL11m(gene name synonym)|uniprotkb:CGI-113(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) ensembl:ENSG00000174547(gene)|ensembl:ENST00000310999(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR006519(Ribosomal protein L11, bacterial-type)|interpro:IPR020783|interpro:IPR020784|interpro:IPR036769|interpro:IPR036796|mint:Q9Y3B7|refseq:NP_057134.1|refseq:NP_733934.1|refseq:NP_733935.1|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:eTr4vzze0vg1fxw97n9C/lXYssU9606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:Q9Y383 intact:EBI-25411384 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:Q9NVH1 intact:EBI-25411384 intact:EBI-1055336|uniprotkb:Q4VWF5|uniprotkb:Q5VZN0|uniprotkb:Q6PK20|uniprotkb:Q6PK70|uniprotkb:Q8NDM2|uniprotkb:Q96CL7|ensembl:ENSP00000366800 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:djc11_human(display_long)|uniprotkb:DNAJC11(gene name)|psi-mi:DNAJC11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) refseq:NP_060668.2|ensembl:ENSG00000007923(gene)|ensembl:ENST00000377577(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0042407"(cristae formation)|go:"GO:0140275"(MIB complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR024586|interpro:IPR036869|mint:Q9NVH1|reactome:R-HSA-8949613 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:+I9CW/QUSn5NIkn2CRTFzq50c/I9606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2F6-1 uniprotkb:P35659 intact:EBI-25411384 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:q9p2f61(display_long)|uniprotkb:ARHGAP20(gene name)|psi-mi:ARHGAP20(display_short)|uniprotkb:KIAA1391(gene name synonym)|uniprotkb:1ad(isoform synonym) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411392|imex:IM-26436-100 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9P2F6-1(isoform-parent) ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6D3crzq0+xCTRAbTAjR+gHLpVhs9606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 rigid:SzLcuOgxQT+BWDprEB2FOU2zZCA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:Q9Y2W2 intact:EBI-21604343 intact:EBI-714455|ensembl:ENSP00000261167|uniprotkb:Q96AY8 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:wbp11_human(display_long)|uniprotkb:SH3 domain-binding protein SNP70(gene name synonym)|uniprotkb:Npw38-binding protein(gene name synonym)|uniprotkb:WBP11(gene name)|psi-mi:WBP11(display_short)|uniprotkb:NPWBP(gene name synonym)|uniprotkb:SNP70(gene name synonym)|uniprotkb:SIPP1(gene name synonym)|uniprotkb:Splicing factor that interacts with PQBP-1 and PP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) rcsb pdb:7ABG|reactome:R-HSA-72163|ensembl:ENSG00000084463(gene)|ensembl:ENST00000261167(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0050699"(WW domain binding)|interpro:IPR019007|mint:Q9Y2W2|rcsb pdb:7ABF|refseq:NP_057396.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:qE03bpSsQiJouJbn6ISt8DnD/pA9606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:O95881 intact:EBI-21604343 intact:EBI-2564581|uniprotkb:B3KQS0|uniprotkb:Q5T1T4|uniprotkb:Q96H50|ensembl:ENSP00000360688 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:txd12_human(display_long)|uniprotkb:TXNDC12(gene name)|psi-mi:TXNDC12(display_short)|uniprotkb:TLP19(gene name synonym)|uniprotkb:Thioredoxin-like protein p19(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 19(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 18(gene name synonym)|uniprotkb:hTLP19(gene name synonym)|uniprotkb:UNQ713/PRO1376(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) refseq:NP_056997.1|ensembl:ENSG00000117862(gene)|ensembl:ENST00000371626(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0019153"("protein-disulfide reductase (glutathione) activity")|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037462|rcsb pdb:1SEN|rcsb pdb:2K8V - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:lgsrfn2RsfqJlKY0WWgUnvmMImM9606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:Q5T3J3 intact:EBI-21604343 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:Q03393 intact:EBI-21604343 intact:EBI-712344|ensembl:ENSP00000280362|uniprotkb:Q8WVG8|uniprotkb:B0YJ87 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:ptps_human(display_long)|uniprotkb:PTS(gene name)|psi-mi:PTS(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) refseq:NP_000308.1|ensembl:ENSG00000150787(gene)|ensembl:ENST00000280362(transcript)|go:"GO:0003874"(6-pyruvoyltetrahydropterin synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007115(6-pyruvoyl tetrahydropterin synthase-related)|interpro:IPR022469|interpro:IPR022470|interpro:IPR038418|rcsb pdb:3I2B|reactome:R-HSA-1474151 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:Qa3bMpzyvRxrvDq9dZUSQlfbpeg9606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:O60331 intact:EBI-21604343 intact:EBI-8869029|uniprotkb:B7Z9E7|uniprotkb:C6GIJ7|uniprotkb:C6GIJ8|uniprotkb:Q7LE07|ensembl:ENSP00000335333 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:pi51c_human(display_long)|uniprotkb:PIP5K1C(gene name)|psi-mi:PIP5K1C(display_short)|uniprotkb:KIAA0589(gene name synonym)|uniprotkb:Type I phosphatidylinositol 4-phosphate 5-kinase gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) ensembl:ENSP00000335333|ensembl:ENST00000537021|ensembl:ENSP00000444779|ensembl:ENST00000539785|ensembl:ENSP00000445992|ensembl:ENST00000589578|ensembl:ENSP00000466363|refseq:NP_001287778.1|refseq:NP_001182662.1|refseq:NP_036530.1|dip:DIP-39809N|ensembl:ENSG00000186111(gene)|ensembl:ENST00000335312(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001931"(uropod)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|rcsb pdb:2G35|rcsb pdb:3H1Z|rcsb pdb:3H85|reactome:R-HSA-1660499|reactome:R-HSA-399955|reactome:R-HSA-6811558|reactome:R-HSA-8856828 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:Xle7kUnkAh2gtQLx2/gl7d2Gz049606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:Q9BYD3 intact:EBI-21604343 intact:EBI-721368|uniprotkb:A6NNV7|uniprotkb:Q9BW07|uniprotkb:Q9H4N2|uniprotkb:Q9Y317|ensembl:ENSP00000253099|ensembl:ENSP00000306902 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:rm04_human(display_long)|uniprotkb:MRPL4(gene name)|psi-mi:MRPL4(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL4m(gene name synonym)|uniprotkb:CDABP0091(orf name)|uniprotkb:CGI-28(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) refseq:NP_057040.2|refseq:NP_666499.1|refseq:NP_666500.1|ensembl:ENSG00000105364(gene)|ensembl:ENST00000253099(transcript)|ensembl:ENST00000307422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013005(Ribosomal protein L4/L1e, bacterial-type)|interpro:IPR023574|mint:Q9BYD3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:v1MODeAQQcG4MKCE/hvEg2NBwmk9606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:P25205 intact:EBI-21604343 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:Q96S66 intact:EBI-21604343 intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|ensembl:ENSP00000349456|ensembl:ENSP00000358986|ensembl:ENSP00000502251|ensembl:ENSP00000502457|ensembl:ENSP00000502648|ensembl:ENSP00000502836 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:clcc1_human(display_long)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940(gene)|ensembl:ENST00000356970(transcript)|ensembl:ENST00000369969(transcript)|ensembl:ENST00000674849(transcript)|ensembl:ENST00000675508(transcript)|ensembl:ENST00000675654(transcript)|ensembl:ENST00000675956(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR009231(Mid-1-related chloride channel) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92888-2 uniprotkb:Q6QNY1 intact:EBI-21604343 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411420|imex:IM-26436-272 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q92888-2(isoform-parent) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 rigid:JQ/DxiQbRGV/M8Wd3U2hLH0Wavw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VW2-1 uniprotkb:Q15149 intact:EBI-25411444 intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763 psi-mi:q86vw21(display_long)|uniprotkb:ARHGEF25(gene name)|psi-mi:ARHGEF25(display_short)|uniprotkb:GEFT(gene name synonym) psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411450|imex:IM-26436-280 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86VW2-1(isoform-parent) go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YTTpAcHBAFhpYSY9Wbb0nctY7889606 rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606 rigid:ntXEpHFFXzPZixMqUbhnm4MGBe4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VW2-1 uniprotkb:Q9NSI2 intact:EBI-25411444 intact:EBI-5457304|ensembl:ENSP00000291634 psi-mi:q86vw21(display_long)|uniprotkb:ARHGEF25(gene name)|psi-mi:ARHGEF25(display_short)|uniprotkb:GEFT(gene name synonym) psi-mi:slx9_human(display_long)|uniprotkb:SLX9(gene name)|psi-mi:SLX9(display_short)|uniprotkb:C21orf70(gene name synonym)|uniprotkb:FAM207A(gene name synonym)|uniprotkb:PRED56(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411450|imex:IM-26436-280 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86VW2-1(isoform-parent) refseq:NP_001303912.1|refseq:NP_001303913.1|refseq:NP_001303914.1|refseq:NP_001303915.1|refseq:NP_001303917.1|refseq:NP_478070.1|ensembl:ENSG00000160256(gene)|ensembl:ENST00000291634(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR028160 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YTTpAcHBAFhpYSY9Wbb0nctY7889606 rogid:pCNahk8BsVfGLtrB/Y290fJCA5g9606 rigid:ntXEpHFFXzPZixMqUbhnm4MGBe4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VW2-1 uniprotkb:P83916 intact:EBI-25411444 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:q86vw21(display_long)|uniprotkb:ARHGEF25(gene name)|psi-mi:ARHGEF25(display_short)|uniprotkb:GEFT(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411450|imex:IM-26436-280 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86VW2-1(isoform-parent) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YTTpAcHBAFhpYSY9Wbb0nctY7889606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:ntXEpHFFXzPZixMqUbhnm4MGBe4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VW2-1 uniprotkb:O15143 intact:EBI-25411444 intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802|ensembl:ENSP00000389631|ensembl:ENSP00000398110|ensembl:ENSP00000403211|ensembl:ENSP00000410238|ensembl:ENSP00000494033|ensembl:ENSP00000496599 psi-mi:q86vw21(display_long)|uniprotkb:ARHGEF25(gene name)|psi-mi:ARHGEF25(display_short)|uniprotkb:GEFT(gene name synonym) psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411450|imex:IM-26436-280 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q86VW2-1(isoform-parent) refseq:NP_005711.1|ensembl:ENSG00000130429(gene)|ensembl:ENST00000427217(transcript)|ensembl:ENST00000431816(transcript)|ensembl:ENST00000451682(transcript)|ensembl:ENST00000455009(transcript)|ensembl:ENST00000458033(transcript)|ensembl:ENST00000645391(transcript)|ensembl:ENST00000646101(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032355"(response to estradiol)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0036284"(tubulobulbar complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030141|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YTTpAcHBAFhpYSY9Wbb0nctY7889606 rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606 rigid:ntXEpHFFXzPZixMqUbhnm4MGBe4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15882-1 uniprotkb:Q9H0C2 intact:EBI-15662868|ensembl:ENSP00000386741 intact:EBI-6149672|ensembl:ENSP00000281154 psi-mi:p15882-1(display_long)|uniprotkb:CHN1(gene name)|psi-mi:CHN1(display_short)|uniprotkb:ARHGAP2(gene name synonym)|uniprotkb:CHN(gene name synonym)|uniprotkb:A-chimaerin(gene name synonym)|uniprotkb:Alpha-chimerin(gene name synonym)|uniprotkb:N-chimerin(gene name synonym)|uniprotkb:Rho GTPase-activating protein 2(gene name synonym) psi-mi:adt4_human(display_long)|uniprotkb:SLC25A31(gene name)|psi-mi:SLC25A31(display_short)|uniprotkb:AAC4(gene name synonym)|uniprotkb:ADP,ATP carrier protein 4(gene name synonym)|uniprotkb:ANT4(gene name synonym)|uniprotkb:Adenine nucleotide translocator 4(gene name synonym)|uniprotkb:SFEC(gene name synonym)|uniprotkb:Solute carrier family 25 member 31(gene name synonym)|uniprotkb:Sperm flagellar energy carrier protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411464|imex:IM-26436-180 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128656(gene)|ensembl:ENST00000409900(transcript)|intact:EBI-718947(isoform-parent)|uniprotkb:P15882-1(isoform-parent) refseq:NP_001305396.1|refseq:NP_112581.1|ensembl:ENSG00000151475(gene)|ensembl:ENST00000281154(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:84hAAd7YQd4QiItoC14jdT4CnRU9606 rogid:41l4B5IjJBVvzEcuNsV2T931oWs9606 rigid:JaiJbDvrR2+0Fyva72SMwXkaQbY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15882-1 uniprotkb:P16333 intact:EBI-15662868|ensembl:ENSP00000386741 intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3 psi-mi:p15882-1(display_long)|uniprotkb:CHN1(gene name)|psi-mi:CHN1(display_short)|uniprotkb:ARHGAP2(gene name synonym)|uniprotkb:CHN(gene name synonym)|uniprotkb:A-chimaerin(gene name synonym)|uniprotkb:Alpha-chimerin(gene name synonym)|uniprotkb:N-chimerin(gene name synonym)|uniprotkb:Rho GTPase-activating protein 2(gene name synonym) psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411464|imex:IM-26436-180 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128656(gene)|ensembl:ENST00000409900(transcript)|intact:EBI-718947(isoform-parent)|uniprotkb:P15882-1(isoform-parent) refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:84hAAd7YQd4QiItoC14jdT4CnRU9606 rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606 rigid:JaiJbDvrR2+0Fyva72SMwXkaQbY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15882-1 uniprotkb:O94887 intact:EBI-15662868|ensembl:ENSP00000386741 intact:EBI-2806886|uniprotkb:Q53QM5|uniprotkb:Q9UFE7|uniprotkb:Q8WU27|ensembl:ENSP00000264042|uniprotkb:B7Z6J8|uniprotkb:F5GZ84 psi-mi:p15882-1(display_long)|uniprotkb:CHN1(gene name)|psi-mi:CHN1(display_short)|uniprotkb:ARHGAP2(gene name synonym)|uniprotkb:CHN(gene name synonym)|uniprotkb:A-chimaerin(gene name synonym)|uniprotkb:Alpha-chimerin(gene name synonym)|uniprotkb:N-chimerin(gene name synonym)|uniprotkb:Rho GTPase-activating protein 2(gene name synonym) psi-mi:farp2_human(display_long)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:PLEKHC3(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 3(gene name synonym)|uniprotkb:FERM domain-including RhoGEF(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411464|imex:IM-26436-180 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000128656(gene)|ensembl:ENST00000409900(transcript)|intact:EBI-718947(isoform-parent)|uniprotkb:P15882-1(isoform-parent) refseq:NP_001269912.1|refseq:NP_001269913.1|refseq:NP_055623.1|ensembl:ENSG00000006607(gene)|ensembl:ENST00000264042(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0022405"(hair cycle process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0033623"(regulation of integrin activation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071800"(podosome assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|reactome:R-HSA-399955|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:84hAAd7YQd4QiItoC14jdT4CnRU9606 rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606 rigid:JaiJbDvrR2+0Fyva72SMwXkaQbY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WZ64 uniprotkb:Q9NUP9 intact:EBI-2836524|uniprotkb:Q9Y4E4|uniprotkb:Q96L70|uniprotkb:Q7Z2L5|uniprotkb:Q4W5D2|intact:EBI-2873601|uniprotkb:Q96P49|ensembl:ENSP00000302895 intact:EBI-1171517|ensembl:ENSP00000278193 psi-mi:arap2_human(display_long)|uniprotkb:ARAP2(gene name)|psi-mi:ARAP2(display_short)|uniprotkb:CENTD1(gene name synonym)|uniprotkb:KIAA0580(gene name synonym)|uniprotkb:Centaurin-delta-1(gene name synonym)|uniprotkb:Protein PARX(gene name synonym) psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411476|imex:IM-26436-72 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056045.2|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037278|interpro:IPR037858|interpro:IPR038508|rcsb pdb:1X40|rcsb pdb:2COD|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|ensembl:ENSP00000302895|ensembl:ENSG00000047365(gene)|ensembl:ENST00000303965(transcript)|refseq:XP_016863188.1 refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YFYTjlg562/jgD4JtXsh0N6Pkxg9606 rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606 rigid:oLmTJJC0BhFGSjRdbNtlSI40n+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WZ64 uniprotkb:O15357 intact:EBI-2836524|uniprotkb:Q9Y4E4|uniprotkb:Q96L70|uniprotkb:Q7Z2L5|uniprotkb:Q4W5D2|intact:EBI-2873601|uniprotkb:Q96P49|ensembl:ENSP00000302895 intact:EBI-1384248|uniprotkb:Q13577|uniprotkb:Q13578|uniprotkb:B2RTX5|ensembl:ENSP00000298229 psi-mi:arap2_human(display_long)|uniprotkb:ARAP2(gene name)|psi-mi:ARAP2(display_short)|uniprotkb:CENTD1(gene name synonym)|uniprotkb:KIAA0580(gene name synonym)|uniprotkb:Centaurin-delta-1(gene name synonym)|uniprotkb:Protein PARX(gene name synonym) psi-mi:ship2_human(display_long)|uniprotkb:INPPL1(gene name)|psi-mi:INPPL1(display_short)|uniprotkb:SHIP2(gene name synonym)|uniprotkb:Inositol polyphosphate phosphatase-like protein 1(gene name synonym)|uniprotkb:Protein 51C(gene name synonym)|uniprotkb:SH2 domain-containing inositol 5'-phosphatase 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411476|imex:IM-26436-72 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056045.2|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037278|interpro:IPR037858|interpro:IPR038508|rcsb pdb:1X40|rcsb pdb:2COD|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|ensembl:ENSP00000302895|ensembl:ENSG00000047365(gene)|ensembl:ENST00000303965(transcript)|refseq:XP_016863188.1 ensembl:ENSP00000298229|ensembl:ENST00000538751|ensembl:ENSP00000444619|refseq:NP_001558.3|refseq:XP_011543301.1|dip:DIP-39733N|ensembl:ENSG00000165458(gene)|ensembl:ENST00000298229(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002376"(immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032868"(response to insulin)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0097178"(ruffle assembly)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036691|interpro:IPR036860|mint:O15357|rcsb pdb:2K4P|rcsb pdb:2KSO|rcsb pdb:2MK2|rcsb pdb:3NR8|rcsb pdb:4A9C|rcsb pdb:5OKM|rcsb pdb:5OKN|rcsb pdb:5OKO|rcsb pdb:5OKP|rcsb pdb:6SQU|rcsb pdb:6SRR|reactome:R-HSA-1660499|reactome:R-HSA-1855204|reactome:R-HSA-912526 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:YFYTjlg562/jgD4JtXsh0N6Pkxg9606 rogid:FmRJZVZS8n00OVhTEfEo5gxIvG49606 rigid:oLmTJJC0BhFGSjRdbNtlSI40n+o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:O75821 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:Q15459 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:Q99417 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:P31153 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:Q9Y5V3 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:P10515 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-2959723|ensembl:ENSP00000280346|uniprotkb:Q16783|uniprotkb:Q53EP3 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:odp2_human(display_long)|uniprotkb:DLAT(gene name)|psi-mi:DLAT(display_short)|uniprotkb:DLTA(gene name synonym)|uniprotkb:70 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:M2 antigen complex 70 kDa subunit(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) refseq:NP_001922.2|ensembl:ENSG00000150768(gene)|ensembl:ENST00000280346(transcript)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P10515|rcsb pdb:1FYC|rcsb pdb:1Y8N|rcsb pdb:1Y8O|rcsb pdb:1Y8P|rcsb pdb:2DNE|rcsb pdb:2PNR|rcsb pdb:2Q8I|rcsb pdb:3B8K|rcsb pdb:3CRK|rcsb pdb:3CRL|rcsb pdb:6CT0|rcsb pdb:6H55|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268|dip:DIP-29496N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:Owh80Cm4CXvo2rPKUhLGc/U47co9606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:O60716 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:Q13895 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-358049|uniprotkb:Q6P5W4|uniprotkb:Q86W44|uniprotkb:Q96IP8|ensembl:ENSP00000230340 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:byst_human(display_long)|uniprotkb:BYSL(gene name)|psi-mi:BYSL(display_short)|uniprotkb:ENP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) refseq:NP_004044.3|dip:DIP-50092N|ensembl:ENSG00000112578(gene)|ensembl:ENST00000230340(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045177"(apical part of cell)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR007955(Bystin)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:QdpF9XYm2gFc5ZodqaGvqTM6XNk9606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZR37 uniprotkb:Q9P2R3 intact:EBI-12891828|intact:EBI-20845503|uniprotkb:A0A1X7SBZ7|uniprotkb:B2RNR7|uniprotkb:Q32Q52|intact:EBI-28971834|uniprotkb:F5H4P0 intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187 psi-mi:pkhg7_human(display_long)|uniprotkb:PLEKHG7(gene name)|psi-mi:PLEKHG7(display_short)|uniprotkb:C12orf74(gene name synonym) psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411486|imex:IM-26436-182 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR040181|refseq:NP_001004330.1|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007266"(Rho protein signal transduction) refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2021/12/01 rogid:Iqr9zRmt9yOZWkio2/VbfnAOkIA9606 rogid:237ungtRc80jqTOKBUnFX9qDUGw9606 rigid:Xabw80XgDFoNxSq87dyxkcvDgTw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:Q9NZR1 intact:EBI-25411548 intact:EBI-4289968|uniprotkb:B4DEW6|ensembl:ENSP00000249700 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:tmod2_human(display_long)|uniprotkb:TMOD2(gene name)|psi-mi:TMOD2(display_short)|uniprotkb:NTMOD(gene name synonym)|uniprotkb:Neuronal tropomodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) ensembl:ENSG00000128872(gene)|ensembl:ENST00000249700(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030426"(growth cone)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051694"(pointed-end actin filament capping)|interpro:IPR004934(Tropomodulin)|interpro:IPR030130|interpro:IPR032675|reactome:R-HSA-390522|refseq:NP_001136357.1|refseq:NP_055363.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:km9yOQf3wlXkMxXa/wKFxquWej09606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:Q9BXP5 intact:EBI-25411548 intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|ensembl:ENSP00000480421|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) ensembl:ENST00000611405(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|reactome:R-HSA-6807505|reactome:R-HSA-72163|ensembl:ENSG00000087087(gene)|refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:Q5MJ07 intact:EBI-25411548 intact:EBI-25411566|ensembl:ENSP00000364661 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:spxn5_human(display_long)|uniprotkb:SPANXN5(gene name)|psi-mi:SPANXN5(display_short)|uniprotkb:Nuclear-associated protein SPAN-Xn5(gene name synonym)|uniprotkb:SPANX family member N5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) ensembl:ENSG00000204363(gene)|ensembl:ENST00000375511(transcript)|interpro:IPR010007(Sperm associated with nucleus, X chromosome)|refseq:NP_001009616.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:f7mCq2DeBaxd1D7rOyzAB/MixaA9606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:P00747 intact:EBI-25411548 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:Q13765 intact:EBI-25411548 intact:EBI-712216|ensembl:ENSP00000349212|ensembl:ENSP00000377469|ensembl:ENSP00000446801|ensembl:ENSP00000447821|ensembl:ENSP00000503345|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|uniprotkb:F8VU71 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) ensembl:ENSG00000196531(gene)|ensembl:ENST00000356769(transcript)|ensembl:ENST00000393891(transcript)|ensembl:ENST00000546392(transcript)|ensembl:ENST00000552540(transcript)|ensembl:ENST00000678066(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006412"(translation)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0015031"(protein transport)|go:"GO:0042060"(wound healing)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|go:"GO:0043403"(skeletal muscle tissue regeneration)|refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:P33992 intact:EBI-25411548 intact:EBI-359410|ensembl:ENSP00000216122|uniprotkb:O60785|uniprotkb:Q14578|uniprotkb:Q9BTJ4|uniprotkb:Q9BWL8 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:mcm5_human(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:CDC46 homolog(gene name synonym)|uniprotkb:P1-CDC46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) ensembl:ENSG00000100297(gene)|ensembl:ENST00000216122(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33992|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_006730.2|reactome:R-HSA-69052|reactome:R-HSA-68962|dip:DIP-27578N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:WjJ4lSpADQFtwT0WnumbRHl/lPw9606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:P06396 intact:EBI-25411548 intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:Q9Y285 intact:EBI-25411548 intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) refseq:NP_004452.1|ensembl:ENSG00000179115(gene)|ensembl:ENST00000314606(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|dip:DIP-53610N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5JYA6 uniprotkb:O15143 intact:EBI-25411548 intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802|ensembl:ENSP00000389631|ensembl:ENSP00000398110|ensembl:ENSP00000403211|ensembl:ENSP00000410238|ensembl:ENSP00000494033|ensembl:ENSP00000496599 psi-mi:q5jya6_human(display_long)|uniprotkb:PLEKHG1(gene name)|psi-mi:PLEKHG1(display_short)|uniprotkb:hCG_22081(orf name) psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411575|imex:IM-26436-144 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR043324|refseq:NP_001025055.1|refseq:NP_001316729.1|refseq:NP_001316730.1|refseq:XP_005267122.1|refseq:XP_006715584.1|refseq:XP_011534285.1|interpro:IPR035899|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like) refseq:NP_005711.1|ensembl:ENSG00000130429(gene)|ensembl:ENST00000427217(transcript)|ensembl:ENST00000431816(transcript)|ensembl:ENST00000451682(transcript)|ensembl:ENST00000455009(transcript)|ensembl:ENST00000458033(transcript)|ensembl:ENST00000645391(transcript)|ensembl:ENST00000646101(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032355"(response to estradiol)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0036284"(tubulobulbar complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030141|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:TrXuNZsnVWelPGEKyqWDtEl/OkM9606 rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606 rigid:tBrK8l6t2Ll72RUfew4fWAixsC8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J31 uniprotkb:Q9NW64 intact:EBI-12517589|ensembl:ENSMUSP00000033560|ensembl:ENSMUSP00000109457|uniprotkb:Q544K7 intact:EBI-2602260|uniprotkb:A6NDM5|uniprotkb:O95607|uniprotkb:B4DLI9|ensembl:ENSP00000199814 psi-mi:ophn1_mouse(display_long)|uniprotkb:Ophn1(gene name)|psi-mi:Ophn1(display_short) psi-mi:rbm22_human(display_long)|uniprotkb:RBM22(gene name)|psi-mi:RBM22(display_short)|uniprotkb:ZC3H16(gene name synonym)|uniprotkb:RNA-binding motif protein 22(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 16(gene name synonym)|uniprotkb:199G4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411536|imex:IM-26436-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031214(gene)|ensembl:ENSMUST00000033560(transcript)|ensembl:ENSMUST00000113826(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q99J31|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|refseq:NP_001300683.1|refseq:NP_001300684.1|refseq:NP_001300685.1|refseq:NP_443208.1 refseq:NP_060517.1|go:"GO:0035690"|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036855|interpro:IPR039171|rcsb pdb:2YTC|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|ensembl:ENST00000199814(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000086589(gene)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033120"(positive regulation of RNA splicing) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xgvDj9c8xw1/D2QQyFY4/ywYlZw10090 rogid:PjcPER8I/RBxwu3oACO1LHxzKAM9606 rigid:3fw4h1ouv2k23Bkrr134Dg0jrYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J31 uniprotkb:O43251 intact:EBI-12517589|ensembl:ENSMUSP00000033560|ensembl:ENSMUSP00000109457|uniprotkb:Q544K7 intact:EBI-746056|uniprotkb:Q5TF71|uniprotkb:Q6IC09|uniprotkb:Q8TD00|uniprotkb:Q8WYB1|uniprotkb:Q96DZ6|uniprotkb:Q96NL7|uniprotkb:Q9UGW4|uniprotkb:Q9UH33|uniprotkb:Q0VH35|uniprotkb:A4F5G8|uniprotkb:A8K5Z5|uniprotkb:Q0PRL5|uniprotkb:B0QYY8|uniprotkb:B0QYY9 psi-mi:ophn1_mouse(display_long)|uniprotkb:Ophn1(gene name)|psi-mi:Ophn1(display_short) psi-mi:rfox2_human(display_long)|uniprotkb:FOX2(gene name synonym)|uniprotkb:RNA-binding motif protein 9(gene name synonym)|uniprotkb:Fox-1 homolog B(gene name synonym)|uniprotkb:Hexaribonucleotide-binding protein 2(gene name synonym)|uniprotkb:Repressor of tamoxifen transcriptional activity(gene name synonym)|uniprotkb:RBFOX2(gene name)|psi-mi:RBFOX2(display_short)|uniprotkb:HRNBP2(gene name synonym)|uniprotkb:RTA(gene name synonym)|uniprotkb:RBM9(gene name synonym)|uniprotkb:RNA-binding protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411536|imex:IM-26436-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031214(gene)|ensembl:ENSMUST00000033560(transcript)|ensembl:ENSMUST00000113826(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q99J31|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|refseq:NP_001300683.1|refseq:NP_001300684.1|refseq:NP_001300685.1|refseq:NP_443208.1 go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010724"(regulation of definitive erythrocyte differentiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001026865.1|refseq:NP_001076045.1|refseq:NP_001076046.1|refseq:NP_055124.1|interpro:IPR017325(RNA-binding protein 9/Ataxin-2-binding protein)|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0140297"(DNA-binding transcription factor binding)|rcsb pdb:2CQ3|reactome:R-HSA-6803529|interpro:IPR025670|refseq:XP_005261494.1|interpro:IPR034237|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:O43251|interpro:IPR035979|refseq:NP_001076047.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xgvDj9c8xw1/D2QQyFY4/ywYlZw10090 rogid:eIocECpScMWGhrZslIle29WUyKs9606 rigid:3fw4h1ouv2k23Bkrr134Dg0jrYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99J31 uniprotkb:P30405 intact:EBI-12517589|ensembl:ENSMUSP00000033560|ensembl:ENSMUSP00000109457|uniprotkb:Q544K7 intact:EBI-5544229|uniprotkb:Q2YDB7|uniprotkb:Q5W131|ensembl:ENSP00000225174 psi-mi:ophn1_mouse(display_long)|uniprotkb:Ophn1(gene name)|psi-mi:Ophn1(display_short) psi-mi:ppif_human(display_long)|uniprotkb:PPIF(gene name)|psi-mi:PPIF(display_short)|uniprotkb:CYP3(gene name synonym)|uniprotkb:Cyclophilin F(gene name synonym)|uniprotkb:Rotamase F(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Mitochondrial cyclophilin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411536|imex:IM-26436-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031214(gene)|ensembl:ENSMUST00000033560(transcript)|ensembl:ENSMUST00000113826(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|mint:Q99J31|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|refseq:NP_001300683.1|refseq:NP_001300684.1|refseq:NP_001300685.1|refseq:NP_443208.1 refseq:NP_005720.1|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010849"(regulation of proton-transporting ATPase activity, rotational mechanism)|go:"GO:0010939"(regulation of necrotic cell death)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0070266"(necroptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:1902445"(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:"GO:1902686"(mitochondrial outer membrane permeabilization involved in programmed cell death)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P30405|rcsb pdb:2BIT|rcsb pdb:2BIU|rcsb pdb:2Z6W|rcsb pdb:3QYU|rcsb pdb:3R49|rcsb pdb:3R4G|rcsb pdb:3R54|rcsb pdb:3R56|rcsb pdb:3R57|rcsb pdb:3R59|rcsb pdb:3RCF|rcsb pdb:3RCG|rcsb pdb:3RCI|rcsb pdb:3RCK|rcsb pdb:3RCL|rcsb pdb:3RD9|rcsb pdb:3RDA|rcsb pdb:3RDB|rcsb pdb:3RDC|rcsb pdb:4J58|rcsb pdb:4J59|rcsb pdb:4J5A|rcsb pdb:4J5B|rcsb pdb:4J5C|rcsb pdb:4J5D|rcsb pdb:4J5E|rcsb pdb:4O8H|rcsb pdb:4O8I|rcsb pdb:4XNC|rcsb pdb:4ZSC|rcsb pdb:4ZSD|rcsb pdb:5A0E|rcsb pdb:5CBT|rcsb pdb:5CBU|rcsb pdb:5CBV|rcsb pdb:5CBW|rcsb pdb:5CCN|rcsb pdb:5CCQ|rcsb pdb:5CCR|rcsb pdb:5CCS|rcsb pdb:6R8L|rcsb pdb:6R8O|rcsb pdb:6R8W|rcsb pdb:6R9S|rcsb pdb:6R9U|rcsb pdb:6R9X|rcsb pdb:6RA1|rcsb pdb:6Y3E|rcsb pdb:6YBM|ensembl:ENSG00000108179(gene)|ensembl:ENST00000225174(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0002931"(response to ischemia)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:xgvDj9c8xw1/D2QQyFY4/ywYlZw10090 rogid:5sa9mIaCM/Fo9PA4NgA1p4c4WIg9606 rigid:3fw4h1ouv2k23Bkrr134Dg0jrYI false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:Q93009 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:Q8NBS9 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-2510815|ensembl:ENSP00000369081|uniprotkb:Q8TCT2|uniprotkb:Q5TCQ0|uniprotkb:Q9BVH9|uniprotkb:Q8ND33|uniprotkb:B2RDM2 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:txnd5_human(display_long)|uniprotkb:TXNDC5(gene name)|psi-mi:TXNDC5(display_short)|uniprotkb:TLP46(gene name synonym)|uniprotkb:Thioredoxin-like protein p46(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 46(gene name synonym)|uniprotkb:UNQ364/PRO700(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 ensembl:ENSG00000239264(gene)|ensembl:ENST00000379757(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2DIZ|rcsb pdb:3UJ1|rcsb pdb:3UVT|rcsb pdb:3WGD|rcsb pdb:3WGE|rcsb pdb:3WGX|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001139021.1|refseq:NP_110437.2|dip:DIP-53700N - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:bz5VVWMPFLTRKwph60UFASjsFN49606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:O15269 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:O75746 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-1047585|uniprotkb:Q96AM8|intact:EBI-2802067|uniprotkb:B3KR64|ensembl:ENSP00000388658 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:cmc1_human(display_long)|uniprotkb:SLC25A12(gene name)|psi-mi:SLC25A12(display_short)|uniprotkb:ARALAR1(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 refseq:NP_003696.2|ensembl:ENSG00000115840(gene)|ensembl:ENST00000422440(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0051592"(response to calcium ion)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:O75746|rcsb pdb:4P5X|rcsb pdb:4P60|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693 - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:NMohxjKtV1fhusocdkdQYZ/ng3I9606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:Q96L21 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-358154|uniprotkb:Q8IUD1|ensembl:ENSP00000298283 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:rl10l_human(display_long)|uniprotkb:RPL10L(gene name)|psi-mi:RPL10L(display_short)|uniprotkb:Large ribosomal subunit protein uL16-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 ensembl:ENSG00000165496(gene)|ensembl:ENST00000298283(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:Q96L21|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|refseq:NP_542784.1|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:6r78yOJs/YAid2MBw7+GEqp1fpY9606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:P30048 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:O00469 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-1047459|uniprotkb:Q59ED2|uniprotkb:Q8N170|intact:EBI-2559757|uniprotkb:B3KWS3|ensembl:ENSP00000353170 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:plod2_human(display_long)|uniprotkb:Lysyl hydroxylase 2(gene name synonym)|uniprotkb:PLOD2(gene name)|psi-mi:PLOD2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 refseq:NP_000926.2|refseq:NP_891988.1|ensembl:ENSG00000152952(gene)|ensembl:ENST00000360060(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O00469|reactome:R-HSA-1650814 - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:sNgFtZzNoKBCz7KUhTBfMG/xxas9606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:Q02809 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-357174|ensembl:ENSP00000196061|uniprotkb:Q96AV9|uniprotkb:Q9H132|uniprotkb:B4DR87|intact:EBI-21357524 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:plod1_human(display_long)|uniprotkb:PLOD(gene name synonym)|uniprotkb:PLOD1(gene name)|psi-mi:PLOD1(display_short)|uniprotkb:LLH(gene name synonym)|uniprotkb:Lysyl hydroxylase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 ensembl:ENSG00000083444(gene)|ensembl:ENST00000196061(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0008544"(epidermis development)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030867"(rough endoplasmic reticulum membrane)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:Q02809|reactome:R-HSA-1650814|refseq:NP_000293.2|refseq:NP_001303249.1 - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:q0eJHb8L3qTbN1PnjQ8L0PcpOLw9606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:Q9C005 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q923Q2 uniprotkb:Q96QB1 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-2608428|uniprotkb:B4DR10|uniprotkb:E9PGY9|uniprotkb:O14868|uniprotkb:O43199|uniprotkb:Q7Z5R8|uniprotkb:Q9C0E0|uniprotkb:Q9H7A2|ensembl:ENSP00000276297|uniprotkb:B8PTI0|uniprotkb:E9PDZ8|uniprotkb:E9PF76|uniprotkb:Q86UC6 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:rhg07_human(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:HP protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411510|imex:IM-26436-142 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 refseq:NP_079043.3|refseq:NP_001157743.1|refseq:NP_006085.2|refseq:NP_872584.2|refseq:XP_005273431.1|refseq:NP_001303597.1|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|interpro:IPR028854|mint:Q96QB1|rcsb pdb:2DKY|rcsb pdb:2GYT|rcsb pdb:2KAP|rcsb pdb:2LOZ|rcsb pdb:3KUQ|rcsb pdb:5FZT|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|refseq:NP_001335013.1|refseq:NP_001335010.1|refseq:NP_001335011.1|refseq:NP_001335012.1|ensembl:ENSG00000164741(gene)|ensembl:ENST00000276297(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0021575"(hindbrain morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030900"(forebrain development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-56928N - comment:mint|function:May function as a GTPase-activating protein - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606 rigid:KGwWFIAeVMX6LLuWNQEluytj0Gw false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15311 uniprotkb:Q15019 intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411599|imex:IM-26436-322 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N - - crc64:12CCBBE30806F92F figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:phLT4aufo8Vlt5AmFGrukH7/qgo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15311 uniprotkb:Q96D71 intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924 intact:EBI-1171195|uniprotkb:Q9BXY9|uniprotkb:Q8NDR7|uniprotkb:Q8WU62|uniprotkb:Q5JWJ7|uniprotkb:Q5JWJ5|uniprotkb:Q5JWJ6|uniprotkb:B7ZBZ8|uniprotkb:B7ZBZ9|uniprotkb:B7ZC00|uniprotkb:J3KP76|intact:EBI-28972584|ensembl:ENSP00000392065 psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym) psi-mi:reps1_human(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411599|imex:IM-26436-322 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_001273540.1|refseq:NP_001273541.1|ensembl:ENSP00000258062|ensembl:ENST00000367663|ensembl:ENSP00000356635|ensembl:ENST00000409812|ensembl:ENSP00000386699|ensembl:ENSP00000392065|ensembl:ENST00000258062|refseq:NP_001122089.1|refseq:NP_114128.3|ensembl:ENSG00000135597(gene)|ensembl:ENST00000450536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR026814|mint:Q96D71|reactome:R-HSA-8856825|reactome:R-HSA-8856828 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606 rogid:3MDo2J3yQfEm6X0eRAutKvrg+Fo9606 rigid:phLT4aufo8Vlt5AmFGrukH7/qgo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15311 uniprotkb:P11234 intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924 intact:EBI-752162|uniprotkb:Q53T32|intact:EBI-4324693|uniprotkb:B4E040|uniprotkb:Q6ZS74|ensembl:ENSP00000272519|ensembl:ENSP00000414224 psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym) psi-mi:ralb_human(display_long)|uniprotkb:RALB(gene name)|psi-mi:RALB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411599|imex:IM-26436-322 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_002872.1|refseq:XP_016860111.1|refseq:XP_005263781.1|refseq:XP_005263784.1|refseq:XP_005263785.1|refseq:XP_005263786.1|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:2KE5|rcsb pdb:2KWI|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-171007|ensembl:ENSG00000144118(gene)|ensembl:ENST00000272519(transcript)|ensembl:ENST00000420510(transcript)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031625"(ubiquitin protein ligase binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606 rogid:vw59HFSN8liew1tYF7x9fgdeFCU9606 rigid:phLT4aufo8Vlt5AmFGrukH7/qgo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15311 uniprotkb:P05412 intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924 intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132 psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym) psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411599|imex:IM-26436-322 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606 rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606 rigid:phLT4aufo8Vlt5AmFGrukH7/qgo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15311 uniprotkb:Q16204 intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924 intact:EBI-1045350|uniprotkb:Q15250|uniprotkb:Q6GSG7|ensembl:ENSP00000263102 psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym) psi-mi:ccdc6_human(display_long)|uniprotkb:Protein H4(gene name synonym)|uniprotkb:Papillary thyroid carcinoma-encoded protein(gene name synonym)|uniprotkb:CCDC6(gene name)|psi-mi:CCDC6(display_short)|uniprotkb:D10S170(gene name synonym)|uniprotkb:TST1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411599|imex:IM-26436-322 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149 refseq:NP_005427.2|ensembl:ENSG00000108091(gene)|ensembl:ENST00000263102(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR019152 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606 rogid:nPX3jyRnTSavY0tKyxDiVo35n8E9606 rigid:phLT4aufo8Vlt5AmFGrukH7/qgo false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q7Z6Z7 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q96KR1 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-2513582|ensembl:ENSP00000265069|uniprotkb:Q9Y687|uniprotkb:Q6P5A3|uniprotkb:B2RNR5|uniprotkb:Q9H6V4|uniprotkb:Q3B7X5|uniprotkb:Q05C08|uniprotkb:Q9NTI1|uniprotkb:Q86UA0|intact:EBI-2560216 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:zfr_human(display_long)|uniprotkb:ZFR(gene name)|psi-mi:ZFR(display_short)|uniprotkb:M-phase phosphoprotein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 ensembl:ENSG00000056097(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|mint:Q96KR1|ensembl:ENST00000265069(transcript)|refseq:NP_057191.2|ensembl:ENSP00000265069|dip:DIP-47293N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:UQQP+tkUcQYka9ez6rMv2F6FXFM9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:O14980 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-355867|uniprotkb:A6NL14|uniprotkb:A8K1K5|uniprotkb:Q63HP8|uniprotkb:Q68CP3|uniprotkb:Q99433|uniprotkb:D6W5E2|ensembl:ENSP00000384863|ensembl:ENSP00000385559|ensembl:ENSP00000385942|ensembl:ENSP00000503167|ensembl:ENSP00000503419|ensembl:ENSP00000503482|ensembl:ENSP00000503572|ensembl:ENSP00000503809|ensembl:ENSP00000504087|ensembl:ENSP00000504198|ensembl:ENSP00000504247|ensembl:ENSP00000504543|ensembl:ENSP00000504594|ensembl:ENSP00000504848 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:xpo1_human(display_long)|uniprotkb:CRM1(gene name synonym)|uniprotkb:XPO1(gene name)|psi-mi:XPO1(display_short)|uniprotkb:Chromosome region maintenance 1 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 ensembl:ENST00000678182(transcript)|ensembl:ENST00000678790(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042493"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|go:"GO:0031267"(small GTPase binding)|mint:O14980|rcsb pdb:1W9C|rcsb pdb:2L1L|rcsb pdb:3GB8|rcsb pdb:4BSM|rcsb pdb:4BSN|rcsb pdb:5DIS|rcsb pdb:6TVO|go:"GO:0031965"(nuclear membrane)|rcsb pdb:7B51|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-168333|reactome:R-HSA-2173788|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3769402|reactome:R-HSA-450520|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-68877|reactome:R-HSA-69273|reactome:R-HSA-9634638|reactome:R-HSA-9648025|reactome:R-HSA-9707616|refseq:NP_003391.1|refseq:XP_011531399.1|ensembl:ENSG00000082898(gene)|ensembl:ENST00000401558(transcript)|ensembl:ENST00000404992(transcript)|ensembl:ENST00000406957(transcript)|ensembl:ENST00000676553(transcript)|ensembl:ENST00000676667(transcript)|ensembl:ENST00000677150(transcript)|ensembl:ENST00000677239(transcript)|ensembl:ENST00000677417(transcript)|ensembl:ENST00000677813(transcript)|ensembl:ENST00000677814(transcript)|ensembl:ENST00000677928(transcript)|ensembl:ENST00000677933(transcript)|refseq:XP_006712157.1|dip:DIP-33678N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:wgxK39oV5wJ6mUuxM/jxqBtukEg9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q9NTJ3 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-356173|uniprotkb:A6NLT9|uniprotkb:O95752|uniprotkb:Q8NDL4|uniprotkb:Q9UNT9|uniprotkb:D3DNL8|ensembl:ENSP00000341382|ensembl:ENSP00000349961 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:smc4_human(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001002800.1|refseq:NP_005487.3|refseq:XP_011510613.1|refseq:NP_001275682.1|ensembl:ENSG00000113810(gene)|ensembl:ENST00000344722(transcript)|ensembl:ENST00000357388(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q9NTJ3|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|dip:DIP-32946N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:P51532 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:P46060 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:O94906 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-536755|uniprotkb:O95109|uniprotkb:Q5VXS5|uniprotkb:Q9H3Z1|uniprotkb:Q9H4T9|uniprotkb:Q9H4U8|uniprotkb:Q9NTE6|ensembl:ENSP00000266079|uniprotkb:B2RAR5|uniprotkb:B3KMC6 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:prp6_human(display_long)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:PRPF6(gene name)|psi-mi:PRPF6(display_short)|uniprotkb:C20orf14(gene name synonym)|uniprotkb:Androgen receptor N-terminal domain-transactivating protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 ensembl:ENSG00000101161(gene)|ensembl:ENST00000266079(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:O94906|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_036601.2|dip:DIP-29006N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:M5ovIXl+1ob6VSKbXZUGU73J7Jk9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q99959 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-702235|intact:EBI-2692870|uniprotkb:D3DUW9|uniprotkb:Q99960|uniprotkb:Q4VC01|uniprotkb:B8QFA1|uniprotkb:B8QGS6|uniprotkb:B8QGS7|uniprotkb:A0AV37|ensembl:ENSP00000070846 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:pkp2_human(display_long)|uniprotkb:PKP2(gene name)|psi-mi:PKP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_004563.2|refseq:NP_001005242.2|ensembl:ENSG00000057294(gene)|ensembl:ENST00000070846(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002159"(desmosome assembly)|go:"GO:0002934"(desmosome organization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007507"(heart development)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:Q99959|rcsb pdb:3TT9|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:kwGWMlk4SDz0xARlBMD1dY9fehQ9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q8N1F7 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:pkk5pooUC4yQShpqjiwNLddfy149606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:P49790 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-286779|uniprotkb:Q5T9I7|intact:EBI-1237421|uniprotkb:E7EPX5|uniprotkb:Q4LE47|uniprotkb:Q7Z743|uniprotkb:B4DIK2|uniprotkb:F6QR24|ensembl:ENSP00000262077 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:nu153_human(display_long)|uniprotkb:Nucleoporin Nup153(gene name synonym)|uniprotkb:153 kDa nucleoporin(gene name synonym)|uniprotkb:NUP153(gene name)|psi-mi:NUP153(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 ensembl:ENSP00000262077|ensembl:ENST00000537253|ensembl:ENSP00000444029|ensembl:ENST00000613258|ensembl:ENSP00000478627|refseq:NP_005115.2|refseq:NP_001265138.1|refseq:NP_001265139.1|dip:DIP-38185N|ensembl:ENSG00000124789(gene)|ensembl:ENST00000262077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043657"(host cell)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046832"(negative regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013913(Nucleoporin, Nup153-like)|interpro:IPR018892|interpro:IPR026054|interpro:IPR036443|mint:P49790|rcsb pdb:2EBQ|rcsb pdb:2EBR|rcsb pdb:2EBV|rcsb pdb:2GQE|rcsb pdb:4U0C|rcsb pdb:4U0D|rcsb pdb:5TSV|rcsb pdb:5TSX|rcsb pdb:6AYA|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:rOax/ikcAu5fmDiCOauVr7Y/fzY9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q14980 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-521611|intact:EBI-28985993|ensembl:ENSP00000377298|uniprotkb:Q14981|uniprotkb:H0YH75|uniprotkb:Q9BTE9 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:numa1_human(display_long)|uniprotkb:SP-H antigen(gene name synonym)|uniprotkb:NUMA1(gene name)|psi-mi:NUMA1(display_short)|uniprotkb:NUMA(gene name synonym)|uniprotkb:NMP22(gene name synonym)|uniprotkb:Nuclear matrix protein-22(gene name synonym)|uniprotkb:Nuclear mitotic apparatus protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 ensembl:ENSG00000137497(gene)|ensembl:ENST00000393695(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_006176.2|refseq:NP_001273490.1|refseq:XP_006718627.1|dip:DIP-32937N|ensembl:ENST00000351960|ensembl:ENSP00000260051|ensembl:ENST00000358965|ensembl:ENSP00000351851|ensembl:ENSP00000377298|ensembl:ENST00000613205|ensembl:ENSP00000480172|ensembl:ENST00000620566|ensembl:ENSP00000478624|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006997"(nucleus organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051798"(positive regulation of hair follicle development)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0055028"(cortical microtubule)|go:"GO:0055048"(anastral spindle assembly)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061673"(mitotic spindle astral microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097427"(microtubule bundle)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099738"(cell cortex region)|go:"GO:1902365"(positive regulation of protein localization to spindle pole body)|go:"GO:1902846"(positive regulation of mitotic spindle elongation)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|go:"GO:1905720"(cytoplasmic microtubule bundle)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR026650|mint:Q14980|rcsb pdb:3RO2|rcsb pdb:5GXW|rcsb pdb:6HC2|rcsb pdb:6QJA|reactome:R-HSA-380320|reactome:R-HSA-68875 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:goAKbcTz6vzGy3T7RlpGPnTCbdk9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q8N5V2 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-718372|uniprotkb:B9A045|uniprotkb:Q53QQ4|uniprotkb:Q53ST7|uniprotkb:Q6GMQ5|uniprotkb:Q9NQD6|uniprotkb:B4DMB8|uniprotkb:E9PC42|ensembl:ENSP00000264051 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:ngef_human(display_long)|uniprotkb:Eph-interacting exchange protein(gene name synonym)|uniprotkb:Neuronal guanine nucleotide exchange factor(gene name synonym)|uniprotkb:NGEF(gene name)|psi-mi:NGEF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001107562.1|refseq:NP_062824.2|refseq:XP_011509225.1|ensembl:ENSG00000066248(gene)|ensembl:ENST00000264051(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035635|interpro:IPR035899|interpro:IPR036028|mint:Q8N5V2|reactome:R-HSA-193648|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:oAu+8njDslYpqxQaq85zzC3hb209606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:P48681 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-10966836|ensembl:ENSP00000357206|uniprotkb:Q5SYZ6|uniprotkb:Q3LIF5|uniprotkb:O00552 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:nest_human(display_long)|uniprotkb:NES(gene name)|psi-mi:NES(display_short)|uniprotkb:Nbla00170(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_006608.1|ensembl:ENSG00000132688(gene)|ensembl:ENST00000368223(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030844"(positive regulation of intermediate filament depolymerization)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0072089"(stem cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR018039|interpro:IPR031211|interpro:IPR039008|mint:P48681 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:IEPf+MleiqNi+QAX57rAn4tYId09606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:P07196 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-475646|uniprotkb:Q16154|uniprotkb:B9ZVN2|uniprotkb:Q8IU72|ensembl:ENSP00000482169 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:nfl_human(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:NEFL(gene name)|psi-mi:NEFL(display_short)|uniprotkb:NF68(gene name synonym)|uniprotkb:NFL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_006149.2|ensembl:ENSG00000277586(gene)|ensembl:ENST00000610854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0030426"(growth cone)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P07196|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:tgdjWnqcql4YMbd89ujbDoqN/Yg9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q9Y676 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-750085|uniprotkb:Q9BS27|uniprotkb:A6NDQ0|uniprotkb:Q659G4|intact:EBI-1050511|ensembl:ENSP00000259873|ensembl:ENSP00000383438|ensembl:ENSP00000397790|ensembl:ENSP00000398494|ensembl:ENSP00000402718|ensembl:ENSP00000414972|ensembl:ENSP00000415703 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:rt18b_human(display_long)|uniprotkb:28S ribosomal protein S18-2, mitochondrial(gene name synonym)|uniprotkb:C6orf14(gene name synonym)|uniprotkb:MRPS18B(gene name)|psi-mi:MRPS18B(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18b(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS40(gene name synonym)|uniprotkb:HSPC183(orf name)|uniprotkb:PTD017(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_054765.1|dip:DIP-29894N|ensembl:ENSG00000203624(gene)|ensembl:ENSG00000204568(gene)|ensembl:ENSG00000223775(gene)|ensembl:ENSG00000226111(gene)|ensembl:ENSG00000227420(gene)|ensembl:ENSG00000229861(gene)|ensembl:ENSG00000233813(gene)|ensembl:ENST00000259873(transcript)|ensembl:ENST00000327800(transcript)|ensembl:ENST00000412451(transcript)|ensembl:ENST00000426945(transcript)|ensembl:ENST00000430402(transcript)|ensembl:ENST00000451032(transcript)|ensembl:ENST00000454427(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0030054"(cell junction)|go:"GO:0032543"(mitochondrial translation)|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|interpro:IPR001648(Ribosomal protein S18)|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|interpro:IPR036870|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|interpro:IPR040054|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|mint:Q9Y676 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:DFGekxKm74bAo8IWpOi8LDITWqc9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:P06396 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:O75477 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q9NZN5 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_001185594.1|refseq:NP_056128.1|refseq:NP_001288013.1|refseq:XP_011541022.1|refseq:XP_016872910.1|ensembl:ENST00000356641|ensembl:ENSP00000349056|ensembl:ENSP00000380942|dip:DIP-37887N|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|rcsb pdb:2OS6|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUY9 uniprotkb:Q8NI60 intact:EBI-3924857|uniprotkb:Q9NW57|uniprotkb:Q9NUN3|uniprotkb:A8K3R9|uniprotkb:Q8IZY6|uniprotkb:Q86WJ3|ensembl:ENSP00000265036|uniprotkb:B4DUT4 intact:EBI-745535|uniprotkb:Q8NCJ6|intact:EBI-1384330|uniprotkb:Q5T7A5|uniprotkb:Q63HK0|uniprotkb:Q9HBQ1|uniprotkb:Q9NQ67|ensembl:ENSP00000355739 psi-mi:dep1b_human(display_long)|uniprotkb:DEPDC1B(gene name)|psi-mi:DEPDC1B(display_short)|uniprotkb:XTP8(gene name synonym)|uniprotkb:HBV X-transactivated gene 8 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 8(gene name synonym) psi-mi:coq8a_human(display_long)|uniprotkb:COQ8A(gene name)|psi-mi:COQ8A(display_short)|uniprotkb:ADCK3(gene name synonym)|uniprotkb:CABC1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)|uniprotkb:PP265(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411615|imex:IM-26436-230 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138680.1|refseq:NP_060839.2|ensembl:ENSG00000035499(gene)|ensembl:ENST00000265036(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 refseq:NP_064632.2|refseq:XP_011542540.1|refseq:XP_011542541.1|refseq:XP_011542542.1|refseq:XP_011542543.1|refseq:XP_005273258.1|refseq:XP_016857341.1|ensembl:ENSG00000163050(gene)|ensembl:ENST00000366777(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|rcsb pdb:4PED|rcsb pdb:5I35 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:hB4cpkhzz9Fhn3JGJr9/KNfHtwE9606 rogid:mR2b+x/tnfsqK1fAzS0qYPijtvw9606 rigid:DtQNhgIwgc2OyT6YSMpUNqvJU1o false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZQ5 uniprotkb:Q91X46 intact:EBI-2477343|intact:EBI-28975233|ensembl:ENSP00000373509|ensembl:ENSP00000434511|uniprotkb:Q8N672 intact:EBI-25411659|ensembl:ENSMUSP00000153124|uniprotkb:Q8CDM0|uniprotkb:Q91VY4|uniprotkb:Q99K14|uniprotkb:Q9DC31 psi-mi:selh_human(display_long)|uniprotkb:SELENOH(gene name)|psi-mi:SELENOH(display_short)|uniprotkb:C11orf31(gene name synonym)|uniprotkb:SELH(gene name synonym) psi-mi:arhg3_mouse(display_long)|uniprotkb:Arhgef3(gene name)|psi-mi:Arhgef3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411688|imex:IM-26436-324 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000211450(gene)|ensembl:ENST00000388857(transcript)|ensembl:ENST00000534355(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR011893(SelT/selW/selH selenoprotein)|interpro:IPR036249|ensembl:ENSP00000373509|ensembl:ENSP00000434511|refseq:NP_734467.1|refseq:NP_001308264.1 ensembl:ENSMUSG00000021895(gene)|ensembl:ENSMUST00000224981(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR044129|rcsb pdb:2Z0Q|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-8980692|reactome:R-MMU-9013026|refseq:NP_001276615.1|refseq:NP_001276616.1|refseq:NP_001276617.1|refseq:NP_082147.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Ew+PKOj0fqVfxYQhF9w6Ni8TmFA9606 rogid:K85WJXcgijRL5lFsJq4kTWMtPyE10090 rigid:Elg2yQxrOUoQClhaGZ2FxKOYkyA false - tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:O00422 intact:EBI-25411746 intact:EBI-1044156|uniprotkb:Q2TTR4|uniprotkb:Q6IAW9|uniprotkb:Q8N606|uniprotkb:Q9UF14|ensembl:ENSP00000475925|uniprotkb:B2R494|uniprotkb:X6RAL5 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:sap18_human(display_long)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 38 protein(gene name synonym)|uniprotkb:2HOR0202(gene name synonym)|uniprotkb:SAP18(gene name)|psi-mi:SAP18(display_short)|uniprotkb:GIG38(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) ensembl:ENSG00000150459(gene)|ensembl:ENST00000607003(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O00422|rcsb pdb:2HDE|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|refseq:NP_005861.2|dip:DIP-33590N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:eJoksFCc7vBoAjJEpnXJvc/yg+Q9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:P61604 intact:EBI-25411746 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:P54886 intact:EBI-25411746 intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:P22314 intact:EBI-25411746 intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:P37802 intact:EBI-25411746 intact:EBI-1056740|intact:EBI-2825986|uniprotkb:Q5JRQ6|uniprotkb:Q5JRQ7|uniprotkb:Q9BUH5|uniprotkb:Q9H4P0|uniprotkb:Q6FGI1|uniprotkb:E9KL39|ensembl:ENSP00000357075|ensembl:ENSP00000357077 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:tagl2_human(display_long)|uniprotkb:TAGLN2(gene name)|psi-mi:TAGLN2(display_short)|uniprotkb:KIAA0120(gene name synonym)|uniprotkb:SM22-alpha homolog(gene name synonym)|uniprotkb:CDABP0035(orf name)|uniprotkb:Epididymis tissue protein Li 7e(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) refseq:NP_003555.1|refseq:NP_001264152.1|refseq:NP_001264153.1|ensembl:ENSG00000158710(gene)|ensembl:ENST00000320307(transcript)|ensembl:ENST00000368097(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031982"(vesicle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000557(Calponin repeat)|interpro:IPR001061("Transgelin (SM22-alpha)")|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:P37802|rcsb pdb:1WYM|reactome:R-HSA-114608 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:JxbMK5SbZWQd+XA9iYc/xuNaVQc9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:P30101 intact:EBI-25411746 intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:Q9Y3C1 intact:EBI-25411746 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:Q96RQ3 intact:EBI-25411746 intact:EBI-2211703|uniprotkb:Q59ES4|uniprotkb:Q9H959|uniprotkb:Q9NS97|ensembl:ENSP00000265594 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:mcca_human(display_long)|uniprotkb:MCCC1(gene name)|psi-mi:MCCC1(display_short)|uniprotkb:MCCA(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) refseq:NP_064551.3|refseq:NP_001280202.1|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q96RQ3|rcsb pdb:2EJM|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895|ensembl:ENSG00000078070(gene)|ensembl:ENST00000265594(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006768"(biotin metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:obze7v7i2yTIIcJjd7laIriNFg89606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:P62993 intact:EBI-25411746 intact:EBI-401755|ensembl:ENSP00000339007|uniprotkb:P29354|uniprotkb:Q14450|uniprotkb:Q63057|uniprotkb:Q63059|ensembl:ENSP00000376345|ensembl:ENSP00000376347|ensembl:ENSP00000496913 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:grb2_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) ensembl:ENSG00000177885(gene)|refseq:NP_002077.1|refseq:NP_987102.1|ensembl:ENST00000316804(transcript)|ensembl:ENST00000392562(transcript)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|ensembl:ENST00000392564(transcript)|ensembl:ENST00000648046(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0012506"(vesicle membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|mint:P62993|rcsb pdb:1AZE|rcsb pdb:1BM2|rcsb pdb:1BMB|rcsb pdb:1CJ1|rcsb pdb:1FHS|rcsb pdb:1FYR|rcsb pdb:1GCQ|rcsb pdb:1GFC|rcsb pdb:1GFD|rcsb pdb:1GHU|rcsb pdb:1GRI|rcsb pdb:1IO6|rcsb pdb:1JYQ|rcsb pdb:1JYR|rcsb pdb:1JYU|rcsb pdb:1QG1|rcsb pdb:1TZE|rcsb pdb:1X0N|rcsb pdb:1ZFP|rcsb pdb:2AOA|rcsb pdb:2AOB|rcsb pdb:2H46|rcsb pdb:2H5K|rcsb pdb:2HUW|rcsb pdb:2VVK|rcsb pdb:2VWF|rcsb pdb:2W0Z|rcsb pdb:3C7I|rcsb pdb:3IMD|rcsb pdb:3IMJ|rcsb pdb:3IN7|rcsb pdb:3IN8|rcsb pdb:3KFJ|rcsb pdb:3MXC|rcsb pdb:3N7Y|rcsb pdb:3N84|rcsb pdb:3N8M|rcsb pdb:3OV1|rcsb pdb:3OVE|rcsb pdb:3MXY|rcsb pdb:3S8L|rcsb pdb:3S8N|rcsb pdb:3S8O|rcsb pdb:3WA4|rcsb pdb:4P9V|rcsb pdb:4P9Z|rcsb pdb:5CDW|rcsb pdb:6ICG|rcsb pdb:6ICH|rcsb pdb:6SDF|rcsb pdb:6VK2|rcsb pdb:6WM1|rcsb pdb:6WO2|reactome:R-HSA-109704|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2029482|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-388841|reactome:R-HSA-389359|reactome:R-HSA-391160|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8865999|reactome:R-HSA-8875360|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8983432|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028335|reactome:R-HSA-5654689|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9645135|reactome:R-HSA-9664422|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|dip:DIP-29229N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:Q04760 intact:EBI-25411746 intact:EBI-1055525|uniprotkb:P78375|uniprotkb:Q5TZW3|uniprotkb:Q96FC0|uniprotkb:Q96J41|uniprotkb:B4DDV0|uniprotkb:Q59EL0|uniprotkb:B2R6P7|ensembl:ENSP00000362463 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:lgul_human(display_long)|uniprotkb:Methylglyoxalase(gene name synonym)|uniprotkb:Aldoketomutase(gene name synonym)|uniprotkb:Glyoxalase I(gene name synonym)|uniprotkb:Ketone-aldehyde mutase(gene name synonym)|uniprotkb:S-D-lactoylglutathione methylglyoxal lyase(gene name synonym)|uniprotkb:GLO1(gene name)|psi-mi:GLO1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) refseq:NP_006699.2|ensembl:ENSG00000124767(gene)|ensembl:ENST00000373365(transcript)|go:"GO:0004462"(lactoylglutathione lyase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004360(Glyoxalase/bleomycin resistance protein/dioxygenase)|interpro:IPR004361(Glyoxalase I)|interpro:IPR018146|interpro:IPR029068|interpro:IPR037523|rcsb pdb:1BH5|rcsb pdb:1FRO|rcsb pdb:1QIN|rcsb pdb:1QIP|rcsb pdb:3VW9|rcsb pdb:3W0T|rcsb pdb:3W0U|reactome:R-HSA-70268 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:Oe1lCyzzD2y1WeArvZ74cYu9M1w9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:Q96I24 intact:EBI-25411746 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:Q96CN4 intact:EBI-25411746 intact:EBI-749523|uniprotkb:B9A6I9|ensembl:ENSP00000270530 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:evi5l_human(display_long)|uniprotkb:Ecotropic viral integration site 5-like protein(gene name synonym)|uniprotkb:EVI5L(gene name)|psi-mi:EVI5L(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) refseq:NP_001153416.1|refseq:NP_660288.1|refseq:XP_005272515.1|refseq:XP_016881728.1|ensembl:ENSG00000142459(gene)|ensembl:ENST00000270530(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:OKfnOqdRupGBmq6gqoeApO0cgG09606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:P33316 intact:EBI-25411746 intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q07890-1 uniprotkb:P12277 intact:EBI-25411746 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:q078901(display_long)|uniprotkb:SOS2(gene name)|psi-mi:SOS2(display_short) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411752|imex:IM-26436-232 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q07890-1(isoform-parent) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CZsyrWgbgewhJ8ENDzpVNhtpKJU9606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:qKG2aLY3KBIg/m7p1RGzeBghXw8 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q9BUZ4 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-3650647|uniprotkb:O75615|uniprotkb:Q14848|uniprotkb:Q2KJU4|uniprotkb:Q2PJN8|ensembl:ENSP00000262395 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:traf4_human(display_long)|uniprotkb:TRAF4(gene name)|psi-mi:TRAF4(display_short)|uniprotkb:CART1(gene name synonym)|uniprotkb:MLN62(gene name synonym)|uniprotkb:RNF83(gene name synonym)|uniprotkb:Cysteine-rich domain associated with RING and Traf domains protein 1(gene name synonym)|uniprotkb:Metastatic lymph node gene 62 protein(gene name synonym)|uniprotkb:RING finger protein 83(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_004286.2|dip:DIP-40910N|ensembl:ENSG00000076604(gene)|ensembl:ENST00000262395(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030323"(respiratory tube development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027138|interpro:IPR037307|interpro:IPR043211|mint:Q9BUZ4|rcsb pdb:2EOD|rcsb pdb:2YUC|rcsb pdb:3ZJB|rcsb pdb:4K8U|rcsb pdb:4M4E|rcsb pdb:5YC1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:9Bjl/NCcleyKgZb7suHw3AVWpG09606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:P17028 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-707773|uniprotkb:O14754|uniprotkb:Q53YE4|uniprotkb:Q6ICR5|uniprotkb:Q8IZN4|ensembl:ENSP00000261332|ensembl:ENSP00000382015 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:znf24_human(display_long)|uniprotkb:Zinc finger protein 191(gene name synonym)|uniprotkb:Zinc finger protein KOX17(gene name synonym)|uniprotkb:Retinoic acid suppression protein A(gene name synonym)|uniprotkb:Zinc finger and SCAN domain-containing protein 3(gene name synonym)|uniprotkb:ZNF24(gene name)|psi-mi:ZNF24(display_short)|uniprotkb:KOX17(gene name synonym)|uniprotkb:ZNF191(gene name synonym)|uniprotkb:ZSCAN3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_008896.2|refseq:XP_005258398.1|refseq:NP_001295052.1|ensembl:ENSG00000172466(gene)|ensembl:ENST00000261332(transcript)|ensembl:ENST00000399061(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR038269|mint:P17028|rcsb pdb:1X6E|rcsb pdb:3LHR - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:JkUMu2FtBQTBFKK1fj5wxMA1bjQ9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:O15260 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q15942 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q9H5H4 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-1210580|uniprotkb:Q569L7|uniprotkb:Q96CX4|ensembl:ENSP00000369777 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:zn768_human(display_long)|uniprotkb:ZNF768(gene name)|psi-mi:ZNF768(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_078947.3|ensembl:ENSG00000169957(gene)|ensembl:ENST00000380412(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H5H4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:kQWxrEzummMO3IQ8wdpnXWFJn1o9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q14157 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q3ZCQ8 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:O15027 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:P55735 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q9BWE0 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-5458270|ensembl:ENSP00000380451|ensembl:ENSP00000388287|ensembl:ENSP00000407714|uniprotkb:D3DWZ1|uniprotkb:Q7LE03|uniprotkb:Q9BUZ6|uniprotkb:Q9NZH2|uniprotkb:Q9UMP5|uniprotkb:C9J3L7 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:repi1_human(display_long)|uniprotkb:REPIN1(gene name)|psi-mi:REPIN1(display_short)|uniprotkb:RIP60(gene name synonym)|uniprotkb:ZNF464(gene name synonym)|uniprotkb:60 kDa origin-specific DNA-binding protein(gene name synonym)|uniprotkb:60 kDa replication initiation region protein(gene name synonym)|uniprotkb:ATT-binding protein(gene name synonym)|uniprotkb:DHFR oribeta-binding protein RIP60(gene name synonym)|uniprotkb:Zinc finger protein 464(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:XP_011514414.1|ensembl:ENST00000444957(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039705|mint:Q9BWE0|ensembl:ENSG00000214022(gene)|ensembl:ENST00000397281(transcript)|ensembl:ENST00000425389(transcript)|refseq:NP_001093165.1|refseq:NP_001093166.1|refseq:NP_037532.2|refseq:NP_055189.2|refseq:XP_005250042.1|refseq:XP_006716010.1|refseq:XP_006716011.1|refseq:XP_006716012.1|refseq:XP_006716015.1|refseq:XP_006716016.1|refseq:XP_016867570.1|refseq:XP_016867571.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:Fu6BEt9A/VSbyo1a4beSLZUd0Ug9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q9P035 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:O43242 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q9HD33 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-2560181|uniprotkb:Q8N5D1|uniprotkb:Q6XRG1|ensembl:ENSP00000417602 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:rm47_human(display_long)|uniprotkb:MRPL47(gene name)|psi-mi:MRPL47(display_short)|uniprotkb:NCM1(gene name synonym)|uniprotkb:Nasopharyngeal carcinoma metastasis-related protein 1(gene name synonym)|uniprotkb:CGI-204(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL29m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_065142.2|refseq:NP_817125.1|ensembl:ENSG00000136522(gene)|ensembl:ENST00000476781(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR010729(Ribosomal protein L47, mitochondrial)|interpro:IPR038340|mint:Q9HD33|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU3|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:Zwk2kFYyc2Efry0CU19e8o7GEW89606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:P10321 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q92616 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q96JJ3 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-3959230|ensembl:ENSP00000290246|ensembl:ENSP00000379673|uniprotkb:Q9NQQ6|uniprotkb:Q5JVZ6|uniprotkb:E1P5T3|uniprotkb:Q9HAH0|uniprotkb:Q9H9L5|uniprotkb:Q9H938|uniprotkb:Q96PA9|uniprotkb:Q96CJ2|uniprotkb:Q96ME5|uniprotkb:Q7Z5G9 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:elmo2_human(display_long)|uniprotkb:ELMO2(gene name)|psi-mi:ELMO2(display_short)|uniprotkb:CED12A(gene name synonym)|uniprotkb:KIAA1834(gene name synonym)|uniprotkb:Protein ced-12 homolog A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 ensembl:ENSG00000062598(gene)|ensembl:ENST00000290246(transcript)|ensembl:ENST00000396391(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006909"(phagocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0048870"(cell motility)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR030713|rcsb pdb:6IDX|rcsb pdb:6IE1|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013408|reactome:R-HSA-9664422|refseq:NP_001305182.1|refseq:NP_573403.1|refseq:NP_877496.1|refseq:XP_005260553.1|refseq:XP_006723917.1|refseq:XP_005260555.1|refseq:XP_005260556.1|refseq:XP_005260557.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:dXWjmEDxNMqr2k3/jdmSPB35MM49606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q92556 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-346417|uniprotkb:Q29R79|uniprotkb:Q96PB0|uniprotkb:Q9H0I1|uniprotkb:A4D1X6|uniprotkb:Q6ZTJ0|ensembl:ENSP00000312185|ensembl:ENSP00000394458|ensembl:ENSP00000406952 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:elmo1_human(display_long)|uniprotkb:ELMO1(gene name)|psi-mi:ELMO1(display_short)|uniprotkb:KIAA0281(gene name synonym)|uniprotkb:Protein ced-12 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:XP_006715868.1|refseq:NP_569709.1|refseq:XP_005249976.1|refseq:NP_001034548.1|refseq:NP_001193409.1|refseq:NP_001193411.1|refseq:NP_055615.8|refseq:XP_011513956.1|refseq:XP_016868327.1|refseq:XP_016868328.1|dip:DIP-31095N|ensembl:ENSG00000155849(gene)|ensembl:ENST00000310758(transcript)|ensembl:ENST00000442504(transcript)|ensembl:ENST00000448602(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0048870"(cell motility)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024574|interpro:IPR030715|mint:Q92556|rcsb pdb:2RQR|rcsb pdb:2VSZ|rcsb pdb:3A98|rcsb pdb:6JPP|rcsb pdb:6TGB|rcsb pdb:6TGC|reactome:R-HSA-164944|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9664422 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:sW9Vj+Vej/oJb9qQxkbtIipDYXI9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q9UBM7 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-1054468|uniprotkb:O60492|uniprotkb:O60717|uniprotkb:B2R6Z2|ensembl:ENSP00000347717|ensembl:ENSP00000384739 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:dhcr7_human(display_long)|uniprotkb:"Sterol Delta(7)-reductase"(gene name synonym)|uniprotkb:DHCR7(gene name)|psi-mi:DHCR7(display_short)|uniprotkb:D7SR(gene name synonym)|uniprotkb:Delta7-sterol reductase(gene name synonym)|uniprotkb:Sterol reductase SR-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_001157289.1|refseq:NP_001351.2|mint:Q9UBM7|reactome:R-HSA-2426168|reactome:R-HSA-6807047|reactome:R-HSA-6807062|interpro:IPR018083|ensembl:ENSG00000172893(gene)|ensembl:ENST00000355527(transcript)|ensembl:ENST00000407721(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0009918"(sterol delta7 reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016132"(brassinosteroid biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0047598"(7-dehydrocholesterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:op53bBpGaOM0Ysy4Bn5q6qXcKgI9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q96A33 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726|ensembl:ENSP00000384888 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:NP_064583.2|ensembl:ENSG00000108588(gene)|ensembl:ENST00000225726(transcript)|ensembl:ENST00000403162(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|go:"GO:0030867"(rough endoplasmic reticulum membrane)|refseq:XP_005257584.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:P56134 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-712794|ensembl:ENSP00000292475|uniprotkb:O76079|uniprotkb:Q96L83|uniprotkb:Q9BTI8|uniprotkb:C9J8H9|uniprotkb:F8W7V3|intact:EBI-11047094|uniprotkb:Q6IBB3 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:atpk_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)|uniprotkb:ATP5J2(gene name synonym)|uniprotkb:ATP5JL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 ensembl:ENSG00000241468(gene)|ensembl:ENST00000292475(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR019344|mint:P56134|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:NP_001003713.1|refseq:NP_004880.1|refseq:NP_001003714.1|refseq:NP_001034267.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:+WS7rjFef6JE+mlZ4Q8TF2A+G0E9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:Q92667 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IZD9 uniprotkb:P28288 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46 psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411696|imex:IM-26436-102 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606 rigid:IaAHg9/dtVX4+C2pVbyRAvmbydk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P07203 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-7209024|uniprotkb:E9PAS1|ensembl:ENSP00000407375|uniprotkb:Q7Z5H1|uniprotkb:Q9BW12|intact:UNK-5370138 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:gpx1_human(display_long)|uniprotkb:GPX1(gene name)|psi-mi:GPX1(display_short)|uniprotkb:Cellular glutathione peroxidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_000572.2|ensembl:ENSG00000233276(gene)|ensembl:ENST00000419783(transcript)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001885"(endothelial cell development)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009609"(response to symbiotic bacterium)|go:"GO:0009650"(UV protection)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042311"(vasodilation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060047"(heart contraction)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902905"(positive regulation of supramolecular fiber organization)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|mint:P07203|rcsb pdb:2F8A|reactome:R-HSA-2142688|reactome:R-HSA-2142712|reactome:R-HSA-2142770|reactome:R-HSA-3299685|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0061136"(regulation of proteasomal protein catabolic process) - - comment:mint|comment:homomint|function:Protects the hemoglobin in erythrocytes from oxidative breakdown figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:1/6I8LekGumy+rLlaLFqCbl1gV09606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P04843 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P12277 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P15374 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-954554|uniprotkb:Q5TBK8|uniprotkb:Q6IBE9|ensembl:ENSP00000366819|uniprotkb:B2R970 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:uchl3_human(display_long)|uniprotkb:Ubiquitin thioesterase L3(gene name synonym)|uniprotkb:UCHL3(gene name)|psi-mi:UCHL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_001257881.1|refseq:NP_005993.1|ensembl:ENSG00000118939(gene)|ensembl:ENST00000377595(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043687"(post-translational protein modification)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|rcsb pdb:1UCH|rcsb pdb:1XD3|rcsb pdb:6ISU|rcsb pdb:6QML|reactome:R-HSA-5689603|reactome:R-HSA-8866652|reactome:R-HSA-8951664|dip:DIP-29135N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:cPnctBpxrgvBKBSaQmhCsyd2nRM9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:Q96JH8 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-744267|intact:EBI-1058572|uniprotkb:Q0VFZ9|uniprotkb:Q75LH3|uniprotkb:Q9BSP5|uniprotkb:Q9H0M6|uniprotkb:Q9NW43|uniprotkb:Q9NWC4|uniprotkb:B7ZL20|uniprotkb:A4D1Z5|uniprotkb:A5YM49|ensembl:ENSP00000382492 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:radil_human(display_long)|uniprotkb:KIAA1849(gene name synonym)|uniprotkb:RADIL(gene name)|psi-mi:RADIL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_060529.4|go:"GO:0051020"(GTPase binding)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037983|rcsb pdb:1UM1|rcsb pdb:3EC8|ensembl:ENSG00000157927(gene)|ensembl:ENST00000399583(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034446"(substrate adhesion-dependent cell spreading) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:GwG8Ipdgc65+IwI8Bvq00yChi7U9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P62333 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P23284 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P22061 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-353343|uniprotkb:Q14661|uniprotkb:Q16556|uniprotkb:Q5VYC1|uniprotkb:Q5VYC2|uniprotkb:Q93061|uniprotkb:Q96II9|uniprotkb:Q99625|uniprotkb:Q9BQV7|uniprotkb:Q9BQV8|uniprotkb:Q9NP03|uniprotkb:A8K109|intact:EBI-2551555|uniprotkb:J3KP72|ensembl:ENSP00000356348|ensembl:ENSP00000420813 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:pimt_human(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short)|uniprotkb:Protein-beta-aspartate methyltransferase(gene name synonym)|uniprotkb:Protein L-isoaspartyl/D-aspartyl methyltransferase(gene name synonym)|uniprotkb:L-isoaspartyl protein carboxyl methyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_001238978.1|refseq:NP_001238982.1|ensembl:ENSG00000120265(gene)|ensembl:ENST00000367378(transcript)|ensembl:ENST00000464889(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0030091"(protein repair)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|mint:P22061|rcsb pdb:1I1N|rcsb pdb:1KR5|reactome:R-HSA-5676934|refseq:NP_005380.2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:wfsjVloc3sqDMXlvFAXQI6Fjilw9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P58546 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-1051736|ensembl:ENSP00000376800 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:mtpn_human(display_long)|uniprotkb:Protein V-1(gene name synonym)|uniprotkb:MTPN(gene name)|psi-mi:MTPN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_665807.1|ensembl:ENSG00000105887(gene)|ensembl:ENST00000393085(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010557"(positive regulation of macromolecule biosynthetic process)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000812"(regulation of barbed-end actin filament capping)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P58546|rcsb pdb:3AAA|rcsb pdb:7DF7|rcsb pdb:7DSA|rcsb pdb:7DSB|dip:DIP-50234N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:kdJ8vNN4yI2ye49iYUNAtH538b49606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:Q70IA6 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-2558739|uniprotkb:Q96M67|uniprotkb:B4DKP3 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:mob2_human(display_long)|uniprotkb:MOB2(gene name)|psi-mi:MOB2(display_short)|uniprotkb:HCCA2(gene name synonym)|uniprotkb:Mob2 homolog(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_001165694.1|refseq:NP_443731.2|interpro:IPR005301(Mob1/phocein)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR036703|mint:Q70IA6 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:bPhfXMdT6x7s05Ufn4VZrMRgcL89606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:Q9ULC4 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-716076|intact:EBI-1048747|uniprotkb:Q502X6|uniprotkb:B4DGY2|ensembl:ENSP00000360367|ensembl:ENSP00000500508 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:mcts1_human(display_long)|uniprotkb:MCTS1(gene name)|psi-mi:MCTS1(display_short)|uniprotkb:MCT1(gene name synonym)|uniprotkb:Multiple copies T-cell malignancies(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_001131026.1|refseq:NP_054779.1|ensembl:ENSG00000232119(gene)|ensembl:ENSG00000288295(gene)|ensembl:ENST00000371317(transcript)|ensembl:ENST00000673335(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0040008"(regulation of growth)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002478(PUA)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR015947(PUA-like)|interpro:IPR016437(Translation machinery-associated RNA binding protein, predicted)|interpro:IPR041366|rcsb pdb:3R90|rcsb pdb:5ONS|rcsb pdb:5VYC|rcsb pdb:6MS4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:g630bQeYIEobBeB8zTPwIiGlPys9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:Q8ND56 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-1384320|uniprotkb:Q76LX7|uniprotkb:Q96AR3|uniprotkb:Q96K73|uniprotkb:Q96SN5|uniprotkb:Q9UFR3|intact:EBI-2563702|uniprotkb:B4DTG6|ensembl:ENSP00000413964|ensembl:ENSP00000459843 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:ls14a_human(display_long)|uniprotkb:C19orf13(gene name synonym)|uniprotkb:FAM61A(gene name synonym)|uniprotkb:Protein SCD6 homolog(gene name synonym)|uniprotkb:Protein FAM61A(gene name synonym)|uniprotkb:Putative alpha-synuclein-binding protein(gene name synonym)|uniprotkb:LSM14A(gene name)|psi-mi:LSM14A(display_short)|uniprotkb:RAP55(gene name synonym)|uniprotkb:RAP55A(gene name synonym)|uniprotkb:RNA-associated protein 55A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_001107565.1|refseq:NP_056393.2|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:Q8ND56|rcsb pdb:6F9W|ensembl:ENSG00000257103(gene)|ensembl:ENSG00000262860(gene)|ensembl:ENST00000433627(transcript)|ensembl:ENST00000570462(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:YW/zx4XyhcZZr3WCZIr1OVpyakA9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P33316 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-353224|uniprotkb:O14785|uniprotkb:Q16708|uniprotkb:Q16860|uniprotkb:Q96Q81|uniprotkb:A8K650|uniprotkb:B4DPR5|uniprotkb:Q6FHN1|uniprotkb:Q6NSA3|ensembl:ENSP00000370376 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:dut_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_001020419.1|refseq:NP_001020420.1|refseq:NP_001939.1|rcsb pdb:1Q5U|rcsb pdb:2HQU|rcsb pdb:3ARA|rcsb pdb:3ARN|rcsb pdb:3EHW|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:5H4J|reactome:R-HSA-499943|ensembl:ENSG00000128951(gene)|ensembl:ENST00000331200(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006260"(DNA replication)|go:"GO:0046081"(dUTP catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157|rcsb pdb:1Q5H|refseq:NP_001317215.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:lHET9Z1Rre4xbVStybz65KJ8QLk9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:Q8N1I0 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-1059186|uniprotkb:O14584|uniprotkb:O94824|uniprotkb:Q8NB45|ensembl:ENSP00000404179 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:dock4_human(display_long)|uniprotkb:DOCK4(gene name)|psi-mi:DOCK4(display_short)|uniprotkb:KIAA0716(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 ensembl:ENST00000428084|ensembl:ENSP00000410746|ensembl:ENSP00000404179|refseq:NP_055520.3|refseq:XP_006716251.1|refseq:XP_006716252.1|ensembl:ENSG00000128512(gene)|ensembl:ENST00000437633(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|interpro:IPR032376|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|interpro:IPR035769|interpro:IPR035892|interpro:IPR036028|interpro:IPR037014|interpro:IPR037811 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:gfkRZEKBQCgsZ/zjJ8NWqL3uJZk9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:Q16527 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-2959737|ensembl:ENSP00000310901|ensembl:ENSP00000450056|uniprotkb:Q93030 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:csrp2_human(display_long)|uniprotkb:CSRP2(gene name)|psi-mi:CSRP2(display_short)|uniprotkb:LMO5(gene name synonym)|uniprotkb:SMLIM(gene name synonym)|uniprotkb:Cysteine-rich protein 2(gene name synonym)|uniprotkb:LIM domain only protein 5(gene name synonym)|uniprotkb:Smooth muscle cell LIM protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_001312.1|ensembl:ENSG00000175183(gene)|ensembl:ENST00000311083(transcript)|ensembl:ENST00000546966(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0060537"(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001287894.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:nyQ01E4UJb21IE/mZhZjXakJoyo9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q3KRB8 uniprotkb:P35520 intact:EBI-25411786|ensembl:ENSP00000392760 intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231 psi-mi:rhgbb_human(display_long)|uniprotkb:ARHGAP11B(gene name)|psi-mi:ARHGAP11B(display_short)|uniprotkb:FAM7B1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 11B(gene name synonym) psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411814|imex:IM-26436-104 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000285077(gene)|ensembl:ENST00000428041(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR042869|reactome:R-HSA-8980692|reactome:R-HSA-9013148|refseq:NP_001034930.1 refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:KEX3at6N7aLiJzwIUAuY2Uy3HQY9606 rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606 rigid:fRLKASbX1lwSqKX9vnVom1MRppA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10911-3 uniprotkb:P04637 intact:EBI-25411852|ensembl:ENSP00000397055 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:p10911-3(display_long)|uniprotkb:Proto-oncogene MCF-2(gene name synonym)|uniprotkb:Var.3(isoform synonym)|uniprotkb:MCF2(gene name)|psi-mi:MCF2(display_short)|uniprotkb:DBL(gene name synonym) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411859|imex:IM-26436-106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1914514(isoform-parent)|ensembl:ENSG00000101977(gene)|ensembl:ENST00000414978(transcript) refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lfpj1tRJi2LhrDStK3dvwKFbwNY9606 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rigid:rJ4AB86hKqz1froszlolTX2EIXg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10911-3 uniprotkb:P61586 intact:EBI-25411852|ensembl:ENSP00000397055 intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175|ensembl:ENSP00000408402|ensembl:ENSP00000503282|ensembl:ENSP00000504180 psi-mi:p10911-3(display_long)|uniprotkb:Proto-oncogene MCF-2(gene name synonym)|uniprotkb:Var.3(isoform synonym)|uniprotkb:MCF2(gene name)|psi-mi:MCF2(display_short)|uniprotkb:DBL(gene name synonym) psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411859|imex:IM-26436-106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1914514(isoform-parent)|ensembl:ENSG00000101977(gene)|ensembl:ENST00000414978(transcript) refseq:NP_001655.1|refseq:NP_001300870.1|dip:DIP-29642N|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|rcsb pdb:3LW8|ensembl:ENSG00000067560(gene)|ensembl:ENST00000418115(transcript)|ensembl:ENST00000445425(transcript)|ensembl:ENST00000678200(transcript)|ensembl:ENST00000679208(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007015"(actin filament organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0017022"(myosin binding)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0001998"(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033688"(regulation of osteoblast proliferation)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0002363"(alpha-beta T cell lineage commitment)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043366"(beta selection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060193"(positive regulation of lipase activity)|go:"GO:0061383"(trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902766"(skeletal muscle satellite cell migration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904695"(positive regulation of vascular associated smooth muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:2RGN|rcsb pdb:3KZ1|go:"GO:0050919"(negative chemotaxis) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lfpj1tRJi2LhrDStK3dvwKFbwNY9606 rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606 rigid:rJ4AB86hKqz1froszlolTX2EIXg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10911-3 uniprotkb:P60953 intact:EBI-25411852|ensembl:ENSP00000397055 intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|uniprotkb:Q9UDI2|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612 psi-mi:p10911-3(display_long)|uniprotkb:Proto-oncogene MCF-2(gene name synonym)|uniprotkb:Var.3(isoform synonym)|uniprotkb:MCF2(gene name)|psi-mi:MCF2(display_short)|uniprotkb:DBL(gene name synonym) psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411859|imex:IM-26436-106 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1914514(isoform-parent)|ensembl:ENSG00000101977(gene)|ensembl:ENST00000414978(transcript) refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0005886"(plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031996"(thioesterase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|dip:DIP-31097N|reactome:R-HSA-983231|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1AN0|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|rcsb pdb:1A4R|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lfpj1tRJi2LhrDStK3dvwKFbwNY9606 rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606 rigid:rJ4AB86hKqz1froszlolTX2EIXg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11274-1 uniprotkb:P68400 intact:EBI-8658094|ensembl:ENSP00000303507|intact:MINT-5222317 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:p11274-1(display_long)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411871|imex:IM-26436-108 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|intact:EBI-712838(isoform-parent)|uniprotkb:P11274-1(isoform-parent) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:+05rHjgKudMBoEHuMYaAwoovXRA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11274-1 uniprotkb:Q96CW1 intact:EBI-8658094|ensembl:ENSP00000303507|intact:MINT-5222317 intact:EBI-297683|ensembl:ENSP00000292807|uniprotkb:A6NE12|uniprotkb:P20172|uniprotkb:P53679|uniprotkb:D3DNT1 psi-mi:p11274-1(display_long)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym) psi-mi:ap2m1_human(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:AP2M1(gene name)|psi-mi:AP2M1(display_short)|uniprotkb:CLAPM1(gene name synonym)|uniprotkb:KIAA0109(gene name synonym)|uniprotkb:Adaptin-mu2(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:HA2 50 kDa subunit(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411871|imex:IM-26436-108 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|intact:EBI-712838(isoform-parent)|uniprotkb:P11274-1(isoform-parent) ensembl:ENSG00000161203(gene)|ensembl:ENST00000292807(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0034622"|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0031623"(receptor internalization)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:Q96CW1|rcsb pdb:1H6E|rcsb pdb:6BNT|rcsb pdb:6URI|reactome:R-HSA-164939|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|reactome:R-HSA-182218|refseq:NP_001020376.1|refseq:NP_004059.2|refseq:NP_001298127.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA9606 rigid:+05rHjgKudMBoEHuMYaAwoovXRA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11274-1 uniprotkb:O95782 intact:EBI-8658094|ensembl:ENSP00000303507|intact:MINT-5222317 intact:EBI-353552|uniprotkb:Q96CI7|uniprotkb:Q96PP6|uniprotkb:Q96PP7|uniprotkb:Q9H070|intact:EBI-28973302|ensembl:ENSP00000351926 psi-mi:p11274-1(display_long)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym) psi-mi:ap2a1_human(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411871|imex:IM-26436-108 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|intact:EBI-712838(isoform-parent)|uniprotkb:P11274-1(isoform-parent) refseq:NP_055018.2|refseq:NP_570603.2|ensembl:ENST00000354293|ensembl:ENSP00000346246|ensembl:ENSP00000351926|ensembl:ENSG00000196961(gene)|ensembl:ENST00000359032(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O95782|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|dip:DIP-33164N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:egkaIAhvIi1FqNr+8KEFeJaYZcc9606 rigid:+05rHjgKudMBoEHuMYaAwoovXRA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22102 uniprotkb:Q6ZSZ5-2 intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77 intact:EBI-21581135 psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym) psi-mi:q6zsz52(display_long)|uniprotkb:ARHGEF18(gene name)|psi-mi:ARHGEF18(display_short)|uniprotkb:KIAA0521(gene name synonym)|uniprotkb:p114(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411883|imex:IM-26436-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1 uniprotkb:Q6ZSZ5-2(isoform-parent) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606 rogid:8bV6ZFH3sgT7nzJ8AVgWbcdjTvg9606 rigid:dPxP3ndVYwBC/uajKvdPXyBCu4g false - tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:P51665 intact:EBI-25411891 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:Q3SY56 intact:EBI-25411891 intact:EBI-11175533|uniprotkb:B3KXS4|ensembl:ENSP00000340799|ensembl:ENSP00000438209 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:sp6_human(display_long)|uniprotkb:SP6(gene name)|psi-mi:SP6(display_short)|uniprotkb:KLF14(gene name synonym)|uniprotkb:Krueppel-like factor 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_001245177.1|refseq:NP_954871.1|refseq:XP_006722178.1|ensembl:ENSG00000189120(gene)|ensembl:ENST00000342234(transcript)|ensembl:ENST00000536300(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042481"(regulation of odontogenesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:wz8BrxPP6bgaMwyYitlW3oAueno9606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:Q8NEM2 intact:EBI-25411891 intact:EBI-744700|uniprotkb:Q96N60|uniprotkb:Q9BVS0|uniprotkb:Q9H6P6|ensembl:ENSP00000306473 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:shcbp_human(display_long)|uniprotkb:SHCBP1(gene name)|psi-mi:SHCBP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_079021.3|ensembl:ENSG00000171241(gene)|ensembl:ENST00000303383(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR039448|mint:Q8NEM2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:VkqhT9kcant5+JwTeubTotVcLfo9606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:P60900 intact:EBI-25411891 intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:Q7Z628 intact:EBI-25411891 intact:EBI-2511306|ensembl:ENSP00000347134|uniprotkb:Q96D82|uniprotkb:Q99903|uniprotkb:Q9UEN6|uniprotkb:Q12773 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:arhg8_human(display_long)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:ARHGEF8(gene name synonym)|uniprotkb:Proto-oncogene p65 Net1(gene name synonym)|uniprotkb:Rho guanine nucleotide exchange factor 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) ensembl:ENSG00000173848(gene)|ensembl:ENST00000355029(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051451"(myoblast migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_001040625.1|refseq:NP_005854.2|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR037853|rcsb pdb:3EO2|rcsb pdb:4XH9|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:Fz61yRg9QxnNYHsRuDGvr3G0z8Y9606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:Q70IA6 intact:EBI-25411891 intact:EBI-2558739|uniprotkb:Q96M67|uniprotkb:B4DKP3 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:mob2_human(display_long)|uniprotkb:MOB2(gene name)|psi-mi:MOB2(display_short)|uniprotkb:HCCA2(gene name synonym)|uniprotkb:Mob2 homolog(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_001165694.1|refseq:NP_443731.2|interpro:IPR005301(Mob1/phocein)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR036703|mint:Q70IA6 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:bPhfXMdT6x7s05Ufn4VZrMRgcL89606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:Q02241 intact:EBI-25411891 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:Q8NCA5 intact:EBI-25411891 intact:EBI-1210765|uniprotkb:B2RNA2|uniprotkb:Q9Y3Y6|intact:EBI-10970131|ensembl:ENSP00000238823 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:fa98a_human(display_long)|uniprotkb:FAM98A(gene name)|psi-mi:FAM98A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_056290.3|go:"GO:0032418"(lysosome localization)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR018797|mint:Q8NCA5|ensembl:ENSG00000119812(gene)|ensembl:ENST00000238823(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006479"(protein methylation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:MEsSX6iNk+0s/sLuUawu0GR9bW89606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:Q9Y224 intact:EBI-25411891 intact:EBI-1104547|ensembl:ENSP00000261700 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A0A024R136 uniprotkb:Q96P47 intact:EBI-25411891 intact:EBI-6873422|uniprotkb:Q96RK3|uniprotkb:Q59EN0|uniprotkb:B3KNZ8|uniprotkb:E9PAL8|ensembl:ENSP00000480655 psi-mi:a0a024r136_human(display_long)|uniprotkb:RACGAP1(gene name)|psi-mi:RACGAP1(display_short)|uniprotkb:hCG_20202(orf name) psi-mi:agap3_human(display_long)|uniprotkb:CENTG3(gene name synonym)|uniprotkb:CRAM-associated GTPase(gene name synonym)|uniprotkb:Centaurin-gamma-3(gene name synonym)|uniprotkb:MR1-interacting protein(gene name synonym)|uniprotkb:AGAP3(gene name)|psi-mi:AGAP3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411916|imex:IM-26436-184 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005654"(nucleoplasm)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_001119575.1|refseq:NP_001119576.1|refseq:NP_001306928.1|refseq:NP_001306929.1|refseq:NP_001306930.1|refseq:NP_001306931.1|refseq:NP_001306932.1|refseq:NP_001306933.1|refseq:NP_037409.2|refseq:XP_006719422.1|refseq:XP_011536540.1|refseq:XP_016874709.1|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP) refseq:NP_001268229.1|refseq:XP_016867223.1|refseq:NP_114152.3|refseq:NP_001036000.1|ensembl:ENSG00000133612(gene)|ensembl:ENST00000622464(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071944"(cell periphery)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q96P47|rcsb pdb:3IHW - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:cjlAuqAG2p8cju3iMfySUeETiAU9606 rogid:kfyXrwC5SFjflXEMQ2wfKoB98Ig9606 rigid:a+wiCWlxut8x1GqmxeTmPSSo+fU false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98171-2 uniprotkb:Q8TAQ2 intact:EBI-25411942|ensembl:ENSP00000359045 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:p98171-2(display_long)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411950|imex:IM-26436-282 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000370028(transcript)|ensembl:ENSG00000089820(gene)|intact:EBI-2796462(isoform-parent) ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:uRCLpXDUjbbdboz1n+GBscN65ig9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:WuH4QfKuPJkVOKeUUo7uz7vhwBY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98171-2 uniprotkb:Q96P70 intact:EBI-25411942|ensembl:ENSP00000359045 intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5 psi-mi:p98171-2(display_long)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym) psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411950|imex:IM-26436-282 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000370028(transcript)|ensembl:ENSG00000089820(gene)|intact:EBI-2796462(isoform-parent) refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:uRCLpXDUjbbdboz1n+GBscN65ig9606 rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606 rigid:WuH4QfKuPJkVOKeUUo7uz7vhwBY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P98171-2 uniprotkb:P01040 intact:EBI-25411942|ensembl:ENSP00000359045 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:p98171-2(display_long)|uniprotkb:Rho-GAP hematopoietic protein C1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 4(gene name synonym)|uniprotkb:p115(gene name synonym)|uniprotkb:ARHGAP4(gene name)|psi-mi:ARHGAP4(display_short)|uniprotkb:KIAA0131(gene name synonym)|uniprotkb:RGC1(gene name synonym)|uniprotkb:RHOGAP4(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411950|imex:IM-26436-282 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000370028(transcript)|ensembl:ENSG00000089820(gene)|intact:EBI-2796462(isoform-parent) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:uRCLpXDUjbbdboz1n+GBscN65ig9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:WuH4QfKuPJkVOKeUUo7uz7vhwBY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZN5-1 uniprotkb:Q96PX9 intact:EBI-9640168|ensembl:ENSP00000380942 intact:EBI-11741362|ensembl:ENSP00000283426 psi-mi:q9nzn5-1(display_long)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short) psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411962|imex:IM-26436-242 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-821440(isoform-parent)|uniprotkb:Q9NZN5-1(isoform-parent)|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rigid:7ewA8kpHHSK0CGoED3Fg/se7JFs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZN5-1 uniprotkb:O14908 intact:EBI-9640168|ensembl:ENSP00000380942 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 psi-mi:q9nzn5-1(display_long)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short) psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411962|imex:IM-26436-242 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-821440(isoform-parent)|uniprotkb:Q9NZN5-1(isoform-parent)|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript) refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rigid:7ewA8kpHHSK0CGoED3Fg/se7JFs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZN5-1 uniprotkb:O15085 intact:EBI-9640168|ensembl:ENSP00000380942 intact:EBI-311099|intact:EBI-28988539|ensembl:ENSP00000354644|uniprotkb:Q5VY40|uniprotkb:D3DVD0|uniprotkb:Q6PFW2 psi-mi:q9nzn5-1(display_long)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short) psi-mi:arhgb_human(display_long)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:PDZ-RhoGEF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411962|imex:IM-26436-242 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-821440(isoform-parent)|uniprotkb:Q9NZN5-1(isoform-parent)|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_055599.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR032919|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037803|interpro:IPR037889|interpro:IPR041020|rcsb pdb:1HTJ|rcsb pdb:1XCG|rcsb pdb:2DLS|rcsb pdb:3KZ1|rcsb pdb:3T06|rcsb pdb:5E6P|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5TYT|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|refseq:NP_937879.1|ensembl:ENSP00000354644|ensembl:ENST00000368194|ensembl:ENSP00000357177|dip:DIP-31622N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rigid:7ewA8kpHHSK0CGoED3Fg/se7JFs false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:Q9UQ16 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-1111783|uniprotkb:A9Z1Y1|uniprotkb:O14982|uniprotkb:O95555|uniprotkb:Q1MTM8|uniprotkb:Q5W129|uniprotkb:Q9H0P3|uniprotkb:Q9H548|uniprotkb:Q9NQ68|uniprotkb:Q9NQN6|uniprotkb:Q6P2G1|ensembl:ENSP00000347457 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:dyn3_human(display_long)|uniprotkb:KIAA0820(gene name synonym)|uniprotkb:DNM3(gene name)|psi-mi:DNM3(display_short)|uniprotkb:Dynamin, testicular(gene name synonym)|uniprotkb:T-dynamin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:NP_001265181.1|refseq:NP_001129599.1|refseq:NP_056384.2|refseq:XP_005245136.1|refseq:XP_005245137.1|ensembl:ENSG00000197959(gene)|ensembl:ENST00000355305(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0006897"(endocytosis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031798"(type 1 metabotropic glutamate receptor binding)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043197"(dendritic spine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0061828"(apical tubulobulbar complex)|go:"GO:0061829"(basal tubulobulbar complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|rcsb pdb:3L43|rcsb pdb:5A3F|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-2132295|go:"GO:0050803"(regulation of synapse structure or activity)|reactome:R-HSA-8856828|reactome:R-HSA-437239|dip:DIP-36244N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:t1g0cjVLI4Bf0hbMJvoM4zKkVYk9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:Q9Y5X1 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:O14827 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-1055500|uniprotkb:Q9UK56|intact:EBI-1058320|uniprotkb:B9EG89|ensembl:ENSP00000265080 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:rgrf2_human(display_long)|uniprotkb:GRF2(gene name synonym)|uniprotkb:Ras guanine nucleotide exchange factor 2(gene name synonym)|uniprotkb:RASGRF2(gene name)|psi-mi:RASGRF2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:NP_008840.1|ensembl:ENSG00000113319(gene)|ensembl:ENST00000265080(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019804|interpro:IPR023578|interpro:IPR030744|interpro:IPR035899|interpro:IPR036964|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:SP64p7eTQmRlLm1WGt5yEdUhAWE9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:O43314 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-3956987|uniprotkb:A1NI53|uniprotkb:A6NGS8|uniprotkb:Q8TB50|ensembl:ENSP00000351126 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:vip2_human(display_long)|uniprotkb:PPIP5K2(gene name)|psi-mi:PPIP5K2(display_short)|uniprotkb:HISPPD1(gene name synonym)|uniprotkb:KIAA0433(gene name synonym)|uniprotkb:VIP2(gene name synonym)|uniprotkb:Diphosphoinositol pentakisphosphate kinase 2(gene name synonym)|uniprotkb:Histidine acid phosphatase domain-containing protein 1(gene name synonym)|uniprotkb:InsP6 and PP-IP5 kinase 2(gene name synonym)|uniprotkb:VIP1 homolog 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:NP_056031.2|ensembl:ENSG00000145725(gene)|ensembl:ENST00000358359(transcript)|go:"GO:0000827"(inositol-1,3,4,5,6-pentakisphosphate kinase activity)|go:"GO:0000828"(inositol hexakisphosphate kinase activity)|go:"GO:0000829"(inositol heptakisphosphate kinase activity)|go:"GO:0000832"(inositol hexakisphosphate 5-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0033857"(diphosphoinositol-pentakisphosphate kinase activity)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0052723"(inositol hexakisphosphate 1-kinase activity)|go:"GO:0052724"(inositol hexakisphosphate 3-kinase activity)|go:"GO:0102092"(5-diphosphoinositol pentakisphosphate 3-kinase activity)|interpro:IPR000560(Histidine acid phosphatase)|interpro:IPR029033|interpro:IPR033379|interpro:IPR037446|interpro:IPR040557|rcsb pdb:3T54|rcsb pdb:3T99|rcsb pdb:3T9A|rcsb pdb:3T9B|rcsb pdb:3T9C|rcsb pdb:3T9D|rcsb pdb:3T9E|rcsb pdb:3T9F|rcsb pdb:4HN2|rcsb pdb:4NZM|rcsb pdb:4NZN|rcsb pdb:4NZO|rcsb pdb:4Q4C|rcsb pdb:4Q4D|rcsb pdb:5BYA|rcsb pdb:5BYB|rcsb pdb:5DGH|rcsb pdb:3T7A|rcsb pdb:5DGI|rcsb pdb:6N5C|reactome:R-HSA-1855167|refseq:NP_001263206.1|refseq:NP_001268400.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:VuHDR+BO1FBS/is7Wo8CU+CPmQU9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:Q6IQ23 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:Q5EBL8 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-1644207|uniprotkb:Q6UWE1|uniprotkb:Q9P0Q1|uniprotkb:D3DVU3|ensembl:ENSP00000239666|ensembl:ENSP00000363578 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:pdz11_human(display_long)|uniprotkb:PDZD11(gene name)|psi-mi:PDZD11(display_short)|uniprotkb:PDZK11(gene name synonym)|uniprotkb:AIPP1(gene name synonym)|uniprotkb:ATPase-interacting PDZ protein(gene name synonym)|uniprotkb:PISP(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase-interacting single-PDZ protein(gene name synonym)|uniprotkb:HSPC227(orf name)|uniprotkb:UNQ6486/PRO21335(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:XP_011529275.1|refseq:NP_057568.1|refseq:XP_016885057.1|ensembl:ENSG00000120509(gene)|ensembl:ENST00000239666(transcript)|ensembl:ENST00000374454(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0098793"(presynapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q5EBL8|reactome:R-HSA-196780|reactome:R-HSA-199220|reactome:R-HSA-425397|reactome:R-HSA-6803544|reactome:R-HSA-936837 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:lbIwGsi2cawUe/V0/Km+ek9pOIE9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:P07237 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:Q3KQU3 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-713229|uniprotkb:Q9HBQ2|uniprotkb:Q8N905|uniprotkb:Q9ULN3|uniprotkb:Q7L8J5|uniprotkb:Q8TAK0|intact:EBI-2511981|intact:EBI-1056140|ensembl:ENSP00000362244|uniprotkb:Q9NW29|uniprotkb:D3DPS4 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:ma7d1_human(display_long)|uniprotkb:MAP7D1(gene name)|psi-mi:MAP7D1(display_short)|uniprotkb:KIAA1187(gene name synonym)|uniprotkb:PARCC1(gene name synonym)|uniprotkb:RPRC1(gene name synonym)|uniprotkb:Proline/arginine-rich coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:Arginine/proline-rich coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:PP2464(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:NP_001273294.1|refseq:NP_001273295.1|ensembl:ENSG00000116871(gene)|ensembl:ENST00000373151(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR008604(E-MAP-115)|mint:Q3KQU3|refseq:NP_060537.3 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:AEal3/uaJsdRBdmijI8nuthBD9k9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:Q3MHD2 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:P50570 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6XZF7-1 uniprotkb:Q9NQY0 intact:EBI-16085546|ensembl:ENSP00000315659 intact:EBI-2653038|uniprotkb:Q9BVG2|uniprotkb:Q9NVY9|ensembl:ENSP00000276416 psi-mi:q6xzf7-1(display_long)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym) psi-mi:bin3_human(display_long)|uniprotkb:BIN3(gene name)|psi-mi:BIN3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25411974|imex:IM-26436-326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|intact:EBI-2483419(isoform-parent)|uniprotkb:Q6XZF7-1(isoform-parent) refseq:XP_011542888.1|refseq:NP_061158.1|ensembl:ENSG00000147439(gene)|ensembl:ENST00000276416(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005737"(cytoplasm)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008104"(protein localization)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051666"(actin cortical patch localization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR037428 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rogid:BPnWqToFqQLXdT5NAUwZIZTraZY9606 rigid:XJp8ngP2Inp8R0PiYJeO4pobEBg false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14185 uniprotkb:O15260 intact:EBI-446740|uniprotkb:A9Z1Z5|ensembl:ENSP00000280333 intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4 psi-mi:dock1_human(display_long)|uniprotkb:180 kDa protein downstream of CRK(gene name synonym)|uniprotkb:DOCK1(gene name)|psi-mi:DOCK1(display_short) psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412002|imex:IM-26436-186 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000280333|dip:DIP-29391N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000150760(gene)|ensembl:ENST00000280333(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|mint:Q14185|rcsb pdb:3L4C|reactome:R-HSA-2029482|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9664422|reactome:R-HSA-983231|interpro:IPR043162|refseq:NP_001371.1 refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SsN4jN+OIbDOnPEthCF7ZdEJrdc9606 rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606 rigid:tbd2389UE8YP3CH8bgarRqFx3VY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14185 uniprotkb:Q9Y297 intact:EBI-446740|uniprotkb:A9Z1Z5|ensembl:ENSP00000280333 intact:EBI-307461|uniprotkb:Q9Y213|uniprotkb:B5MD49|uniprotkb:Q5W142|ensembl:ENSP00000359206|uniprotkb:Q5W141 psi-mi:dock1_human(display_long)|uniprotkb:180 kDa protein downstream of CRK(gene name synonym)|uniprotkb:DOCK1(gene name)|psi-mi:DOCK1(display_short) psi-mi:fbw1a_human(display_long)|uniprotkb:BTRC(gene name)|psi-mi:BTRC(display_short)|uniprotkb:BTRCP(gene name synonym)|uniprotkb:FBW1A(gene name synonym)|uniprotkb:FBXW1A(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP(gene name synonym)|uniprotkb:E3RSIkappaB(gene name synonym)|uniprotkb:pIkappaBalpha-E3 receptor subunit(gene name synonym)|uniprotkb:Epididymis tissue protein Li 2a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412002|imex:IM-26436-186 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000280333|dip:DIP-29391N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000150760(gene)|ensembl:ENST00000280333(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|mint:Q14185|rcsb pdb:3L4C|reactome:R-HSA-2029482|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9664422|reactome:R-HSA-983231|interpro:IPR043162|refseq:NP_001371.1 refseq:NP_003930.1|refseq:NP_378663.1|ensembl:ENSG00000166167(gene)|ensembl:ENST00000370187(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:1990757"(ubiquitin ligase activator activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|interpro:IPR021977|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR036047|interpro:IPR036322|mint:Q9Y297|rcsb pdb:1P22|rcsb pdb:2P64|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6TTU|reactome:R-HSA-1169091|reactome:R-HSA-1170546|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-195253|reactome:R-HSA-202424|go:"GO:0051726"(regulation of cell cycle)|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-3769402|reactome:R-HSA-400253|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-983168|dip:DIP-31607N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SsN4jN+OIbDOnPEthCF7ZdEJrdc9606 rogid:9/bXDY6YvJWvP6iMSgOPT9CNGAE9606 rigid:tbd2389UE8YP3CH8bgarRqFx3VY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14185 uniprotkb:Q6NXT1 intact:EBI-446740|uniprotkb:A9Z1Z5|ensembl:ENSP00000280333 intact:EBI-10102770|uniprotkb:Q6ZSB1|uniprotkb:Q9UGV1|intact:EBI-28972042|ensembl:ENSP00000215941 psi-mi:dock1_human(display_long)|uniprotkb:180 kDa protein downstream of CRK(gene name synonym)|uniprotkb:DOCK1(gene name)|psi-mi:DOCK1(display_short) psi-mi:anr54_human(display_long)|uniprotkb:ANKRD54(gene name)|psi-mi:ANKRD54(display_short)|uniprotkb:LIAR(gene name synonym)|uniprotkb:Lyn-interacting ankyrin repeat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412002|imex:IM-26436-186 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000280333|dip:DIP-29391N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000150760(gene)|ensembl:ENST00000280333(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|mint:Q14185|rcsb pdb:3L4C|reactome:R-HSA-2029482|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9664422|reactome:R-HSA-983231|interpro:IPR043162|refseq:NP_001371.1 ensembl:ENSP00000215941|refseq:NP_620152.1|ensembl:ENSG00000100124(gene)|ensembl:ENST00000215941(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:1902531"(regulation of intracellular signal transduction)|interpro:IPR002110(Ankyrin)|interpro:IPR036770 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:SsN4jN+OIbDOnPEthCF7ZdEJrdc9606 rogid:Ku7TbISn+yxM8+a5FED4ANkydEg9606 rigid:tbd2389UE8YP3CH8bgarRqFx3VY false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P51571 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P28074 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:O14818 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:Q9H3U1 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-1048763|uniprotkb:Q7L3Y6|uniprotkb:Q9H3U8|uniprotkb:Q9NSE8|uniprotkb:Q9NSE9|uniprotkb:A8K6F7|ensembl:ENSP00000407487 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:un45a_human(display_long)|uniprotkb:GCUNC-45(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 1(gene name synonym)|uniprotkb:UNC45A(gene name)|psi-mi:UNC45A(display_short)|uniprotkb:SMAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_001034764.1|refseq:NP_061141.2|refseq:XP_011520081.1|ensembl:ENSG00000140553(gene)|ensembl:ENST00000418476(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019734|interpro:IPR024660|rcsb pdb:2DBA|refseq:NP_001310548.1|refseq:NP_001310550.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:P/N+VqGUtK2vWzHyKq6UzC4xxdo9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:Q9NZ01 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-2877718|ensembl:ENSP00000215567|uniprotkb:Q9BWK3|uniprotkb:Q6IBB2|uniprotkb:O75350|uniprotkb:Q9Y6P0|uniprotkb:B2RD55 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:tecr_human(display_long)|uniprotkb:TECR(gene name)|psi-mi:TECR(display_short)|uniprotkb:GPSN2(gene name synonym)|uniprotkb:SC2(gene name synonym)|uniprotkb:Synaptic glycoprotein SC2(gene name synonym)|uniprotkb:Trans-2,3-enoyl-CoA reductase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 ensembl:ENSG00000099797(gene)|ensembl:ENST00000215567(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102758"(very-long-chain enoyl-CoA reductase activity)|interpro:IPR001104(3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal)|interpro:IPR029071|interpro:IPR039357|mint:Q9NZ01|rcsb pdb:2DZJ|reactome:R-HSA-75876|refseq:NP_612510.1|refseq:NP_001308099.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:qk8o3QKxQuUvJ3SIlsICJoAnzXg9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:Q6NUK1 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-4289949|uniprotkb:Q705K4|uniprotkb:B7ZAI9|uniprotkb:Q5T331|uniprotkb:Q9P129|uniprotkb:Q5T485|uniprotkb:Q6PJJ9|ensembl:ENSP00000457733|ensembl:ENSP00000491572 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:scmc1_human(display_long)|uniprotkb:SLC25A24(gene name)|psi-mi:SLC25A24(display_short)|uniprotkb:APC1(gene name synonym)|uniprotkb:MCSC1(gene name synonym)|uniprotkb:SCAMC1(gene name synonym)|uniprotkb:Mitochondrial ATP-Mg/Pi carrier protein 1(gene name synonym)|uniprotkb:"Mitochondrial Ca(2+)-dependent solute carrier protein 1"(gene name synonym)|uniprotkb:Small calcium-binding mitochondrial carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_037518.3|refseq:NP_998816.1|ensembl:ENSG00000085491(gene)|ensembl:ENSG00000284468(gene)|ensembl:ENST00000565488(transcript)|ensembl:ENST00000640416(transcript)|go:"GO:0005347"(ATP transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0010941"(regulation of cell death)|go:"GO:0015867"(ATP transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0071277"(cellular response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002167(Graves disease carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR018247|interpro:IPR023395|mint:Q6NUK1|rcsb pdb:4N5X|rcsb pdb:4ZCU|rcsb pdb:4ZCV - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:2zVynZiDVY5UzziL6TAmqK/fkB09606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P78406 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-724495|uniprotkb:O15306|uniprotkb:Q3SYL7|uniprotkb:Q5TCH8|uniprotkb:Q6V708|uniprotkb:Q9H100|uniprotkb:Q9NQM6|ensembl:ENSP00000360286|ensembl:ENSP00000379181|ensembl:ENSP00000379182|uniprotkb:A8K882 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:rae1l_human(display_long)|uniprotkb:mRNA-associated protein mrnp 41(gene name synonym)|uniprotkb:Rae1 protein homolog(gene name synonym)|uniprotkb:RAE1(gene name)|psi-mi:RAE1(display_short)|uniprotkb:MRNP41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_001015885.1|refseq:NP_003601.1|ensembl:ENSG00000101146(gene)|ensembl:ENST00000371242(transcript)|ensembl:ENST00000395840(transcript)|ensembl:ENST00000395841(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037631|mint:P78406|rcsb pdb:3MMY|rcsb pdb:4OWR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|interpro:IPR019775|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|refseq:XP_011527390.1|refseq:XP_011527391.1|refseq:XP_005260639.2|dip:DIP-41063N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:JK4Y5p3WUcHFXBXyhhqCnDnG49c9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P28070 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P49721 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P25786 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P35658 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:Q13765 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-712216|ensembl:ENSP00000349212|ensembl:ENSP00000377469|ensembl:ENSP00000446801|ensembl:ENSP00000447821|ensembl:ENSP00000503345|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|uniprotkb:F8VU71 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 ensembl:ENSG00000196531(gene)|ensembl:ENST00000356769(transcript)|ensembl:ENST00000393891(transcript)|ensembl:ENST00000546392(transcript)|ensembl:ENST00000552540(transcript)|ensembl:ENST00000678066(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006412"(translation)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0015031"(protein transport)|go:"GO:0042060"(wound healing)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|go:"GO:0043403"(skeletal muscle tissue regeneration)|refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P14649 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-358570|ensembl:ENSP00000446643|ensembl:ENSP00000450385 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:myl6b_human(display_long)|uniprotkb:MYL6B(gene name)|psi-mi:MYL6B(display_short)|uniprotkb:MLC1SA(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym)|uniprotkb:Myosin light chain 1 slow-twitch muscle A isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_001186558.1|refseq:NP_002466.1|ensembl:ENSG00000196465(gene)|ensembl:ENST00000550443(transcript)|ensembl:ENST00000553066(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|reactome:R-HSA-445355 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:S0/S5hUxfyyve1JDMojIggOSBb89606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P07195 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q63358 uniprotkb:P84077 intact:EBI-6251137|ensembl:ENSRNOP00000048368|ensembl:ENSRNOP00000073856 intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980 psi-mi:myo9b_rat(display_long)|uniprotkb:Myo9b(gene name)|psi-mi:Myo9b(display_short)|uniprotkb:Myr5(gene name synonym)|uniprotkb:Unconventional myosin-9b(gene name synonym) psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412031|imex:IM-26436-188 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000016256(gene)|ensembl:ENSRNOT00000045099(transcript)|ensembl:ENSRNOT00000081321(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-RNO-2029482|reactome:R-RNO-8980692|reactome:R-RNO-8985586|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9035034|rgd:3146 refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/03/03 rogid:21LUI1efFh+iwk7wApWDwu3gZRM10116 rogid:zray9asm6VonxpuJpv0dRBspPt89606 rigid:cPOlYC6M0bBl4rEEw0T9Bow6t/s false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52757-1 uniprotkb:Q96JH8 intact:EBI-8603194|ensembl:ENSP00000222792|intact:MINT-1420886 intact:EBI-744267|intact:EBI-1058572|uniprotkb:Q0VFZ9|uniprotkb:Q75LH3|uniprotkb:Q9BSP5|uniprotkb:Q9H0M6|uniprotkb:Q9NW43|uniprotkb:Q9NWC4|uniprotkb:B7ZL20|uniprotkb:A4D1Z5|uniprotkb:A5YM49|ensembl:ENSP00000382492 psi-mi:p52757-1(display_long)|uniprotkb:CHN2(gene name)|psi-mi:CHN2(display_short)|uniprotkb:ARHGAP3(gene name synonym)|uniprotkb:BCH(gene name synonym)|uniprotkb:Beta-chimerin(gene name synonym)|uniprotkb:Rho GTPase-activating protein 3(gene name synonym) psi-mi:radil_human(display_long)|uniprotkb:KIAA1849(gene name synonym)|uniprotkb:RADIL(gene name)|psi-mi:RADIL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412067|imex:IM-26436-284 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106069(gene)|ensembl:ENST00000222792(transcript)|intact:EBI-714925(isoform-parent)|uniprotkb:P52757-1(isoform-parent) refseq:NP_060529.4|go:"GO:0051020"(GTPase binding)|interpro:IPR000159(Ras-association)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037983|rcsb pdb:1UM1|rcsb pdb:3EC8|ensembl:ENSG00000157927(gene)|ensembl:ENST00000399583(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005874"(microtubule)|go:"GO:0007165"(signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034446"(substrate adhesion-dependent cell spreading) - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:drcrV4yAbGTuSAJYNjjopBQxFDM9606 rogid:GwG8Ipdgc65+IwI8Bvq00yChi7U9606 rigid:/RyT0CREKeEYzNgEZFYxScORliM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52757-1 uniprotkb:P16333 intact:EBI-8603194|ensembl:ENSP00000222792|intact:MINT-1420886 intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3 psi-mi:p52757-1(display_long)|uniprotkb:CHN2(gene name)|psi-mi:CHN2(display_short)|uniprotkb:ARHGAP3(gene name synonym)|uniprotkb:BCH(gene name synonym)|uniprotkb:Beta-chimerin(gene name synonym)|uniprotkb:Rho GTPase-activating protein 3(gene name synonym) psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412067|imex:IM-26436-284 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000106069(gene)|ensembl:ENST00000222792(transcript)|intact:EBI-714925(isoform-parent)|uniprotkb:P52757-1(isoform-parent) refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N - comment:mint - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:drcrV4yAbGTuSAJYNjjopBQxFDM9606 rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606 rigid:/RyT0CREKeEYzNgEZFYxScORliM false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43295-2 uniprotkb:Q9Y6N7 intact:EBI-11063100|ensembl:ENSP00000353587 intact:EBI-399762|uniprotkb:Q7Z300|uniprotkb:Q9BUS7|uniprotkb:D3DU36|uniprotkb:B2RXI1|uniprotkb:E9PD49|uniprotkb:Q1RMC7|ensembl:ENSP00000420321 psi-mi:o43295-2(display_long)|uniprotkb:SRGAP3(gene name)|psi-mi:SRGAP3(display_short)|uniprotkb:ARHGAP14(gene name synonym)|uniprotkb:KIAA0411(gene name synonym)|uniprotkb:KIAA1156(gene name synonym)|uniprotkb:MEGAP(gene name synonym)|uniprotkb:Mental disorder-associated GAP(gene name synonym)|uniprotkb:Rho GTPase-activating protein 14(gene name synonym)|uniprotkb:SRGAP2(gene name synonym)|uniprotkb:WAVE-associated Rac GTPase-activating protein(gene name synonym)|uniprotkb:MEGAPb(isoform synonym)|uniprotkb:srGAP3b(isoform synonym) psi-mi:robo1_human(display_long)|uniprotkb:ROBO1(gene name)|psi-mi:ROBO1(display_short)|uniprotkb:DUTT1(gene name synonym)|uniprotkb:H-Robo-1(gene name synonym)|uniprotkb:Deleted in U twenty twenty(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412014|imex:IM-26436-146 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196220(gene)|ensembl:ENST00000360413(transcript)|intact:EBI-368166(isoform-parent)|uniprotkb:O43295-2(isoform-parent) refseq:NP_001139317.1|refseq:NP_002932.1|refseq:NP_598334.2|ensembl:ENSP00000420321|ensembl:ENST00000467549|ensembl:ENSP00000417992|ensembl:ENST00000495273|ensembl:ENSP00000420637|refseq:XP_006713340.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032986|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2EO9|rcsb pdb:2V9Q|rcsb pdb:2V9R|rcsb pdb:2V9T|rcsb pdb:3WIH|rcsb pdb:4HLJ|rcsb pdb:5O5G|rcsb pdb:5O5I|rcsb pdb:5OPE|rcsb pdb:6A77|rcsb pdb:6A78|ensembl:ENSG00000169855(gene)|ensembl:ENST00000464233(transcript)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007399"(nervous system development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0009986"(cell surface)|refseq:XP_016862472.1|dip:DIP-33034N|rcsb pdb:6A79|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-8985801|reactome:R-HSA-9010553 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EatjevYRtQ8UAObKRXgUkKHN3jY9606 rogid:LLHEVlylzhWB/zr77pQrNizgVsg9606 rigid:RdPBMhQ8zIAkO/I67srDjhWuLzk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43295-2 uniprotkb:Q70E73 intact:EBI-11063100|ensembl:ENSP00000353587 intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543 psi-mi:o43295-2(display_long)|uniprotkb:SRGAP3(gene name)|psi-mi:SRGAP3(display_short)|uniprotkb:ARHGAP14(gene name synonym)|uniprotkb:KIAA0411(gene name synonym)|uniprotkb:KIAA1156(gene name synonym)|uniprotkb:MEGAP(gene name synonym)|uniprotkb:Mental disorder-associated GAP(gene name synonym)|uniprotkb:Rho GTPase-activating protein 14(gene name synonym)|uniprotkb:SRGAP2(gene name synonym)|uniprotkb:WAVE-associated Rac GTPase-activating protein(gene name synonym)|uniprotkb:MEGAPb(isoform synonym)|uniprotkb:srGAP3b(isoform synonym) psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412014|imex:IM-26436-146 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196220(gene)|ensembl:ENST00000360413(transcript)|intact:EBI-368166(isoform-parent)|uniprotkb:O43295-2(isoform-parent) refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EatjevYRtQ8UAObKRXgUkKHN3jY9606 rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606 rigid:RdPBMhQ8zIAkO/I67srDjhWuLzk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43295-2 uniprotkb:P30414 intact:EBI-11063100|ensembl:ENSP00000353587 intact:EBI-1642562|ensembl:ENSP00000232978 psi-mi:o43295-2(display_long)|uniprotkb:SRGAP3(gene name)|psi-mi:SRGAP3(display_short)|uniprotkb:ARHGAP14(gene name synonym)|uniprotkb:KIAA0411(gene name synonym)|uniprotkb:KIAA1156(gene name synonym)|uniprotkb:MEGAP(gene name synonym)|uniprotkb:Mental disorder-associated GAP(gene name synonym)|uniprotkb:Rho GTPase-activating protein 14(gene name synonym)|uniprotkb:SRGAP2(gene name synonym)|uniprotkb:WAVE-associated Rac GTPase-activating protein(gene name synonym)|uniprotkb:MEGAPb(isoform synonym)|uniprotkb:srGAP3b(isoform synonym) psi-mi:nktr_human(display_long)|uniprotkb:NKTR(gene name)|psi-mi:NKTR(display_short)|uniprotkb:Natural-killer cells cyclophilin-related protein(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase NKTR(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412014|imex:IM-26436-146 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196220(gene)|ensembl:ENST00000360413(transcript)|intact:EBI-368166(isoform-parent)|uniprotkb:O43295-2(isoform-parent) refseq:NP_005376.2|ensembl:ENSG00000114857(gene)|ensembl:ENST00000232978(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P30414|rcsb pdb:2HE9 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EatjevYRtQ8UAObKRXgUkKHN3jY9606 rogid:+klgWL+1/tJS3kNQb6HDqh7n4FY9606 rigid:RdPBMhQ8zIAkO/I67srDjhWuLzk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43295-2 uniprotkb:Q8N264 intact:EBI-11063100|ensembl:ENSP00000353587 intact:EBI-988764|ensembl:ENSP00000378611|uniprotkb:Q4KMG1|uniprotkb:Q6ZNV3|uniprotkb:Q86TI5|uniprotkb:Q86WE4|uniprotkb:Q9H0T6 psi-mi:o43295-2(display_long)|uniprotkb:SRGAP3(gene name)|psi-mi:SRGAP3(display_short)|uniprotkb:ARHGAP14(gene name synonym)|uniprotkb:KIAA0411(gene name synonym)|uniprotkb:KIAA1156(gene name synonym)|uniprotkb:MEGAP(gene name synonym)|uniprotkb:Mental disorder-associated GAP(gene name synonym)|uniprotkb:Rho GTPase-activating protein 14(gene name synonym)|uniprotkb:SRGAP2(gene name synonym)|uniprotkb:WAVE-associated Rac GTPase-activating protein(gene name synonym)|uniprotkb:MEGAPb(isoform synonym)|uniprotkb:srGAP3b(isoform synonym) psi-mi:rhg24_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412014|imex:IM-26436-146 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196220(gene)|ensembl:ENST00000360413(transcript)|intact:EBI-368166(isoform-parent)|uniprotkb:O43295-2(isoform-parent) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0035021"(negative regulation of Rac protein signal transduction)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0042995"(cell projection)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR000198(RhoGAP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|refseq:NP_112595.2|refseq:NP_001020787.2|refseq:NP_001036134.1|refseq:XP_011530602.1|dip:DIP-35520N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EatjevYRtQ8UAObKRXgUkKHN3jY9606 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rigid:RdPBMhQ8zIAkO/I67srDjhWuLzk false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNL6-1 uniprotkb:P31040 intact:EBI-25412104 intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932 psi-mi:q6znl61(display_long)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym) psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412111|imex:IM-26436-148 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZNL6-1(isoform-parent) refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606 rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606 rigid:Cgclm0SwUx2gR3ne74HyQS4N5cA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNL6-1 uniprotkb:Q13185 intact:EBI-25412104 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:q6znl61(display_long)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412111|imex:IM-26436-148 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZNL6-1(isoform-parent) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:Cgclm0SwUx2gR3ne74HyQS4N5cA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNL6-1 uniprotkb:P25205 intact:EBI-25412104 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:q6znl61(display_long)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412111|imex:IM-26436-148 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZNL6-1(isoform-parent) refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 rigid:Cgclm0SwUx2gR3ne74HyQS4N5cA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNL6-1 uniprotkb:P61962 intact:EBI-25412104 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:q6znl61(display_long)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412111|imex:IM-26436-148 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZNL6-1(isoform-parent) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rigid:Cgclm0SwUx2gR3ne74HyQS4N5cA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNL6-1 uniprotkb:Q9UJU6 intact:EBI-25412104 intact:EBI-751783|uniprotkb:P84070|uniprotkb:Q6IAI8|uniprotkb:Q96F30|uniprotkb:Q96K74|uniprotkb:Q9HBN8|uniprotkb:Q9NR72|uniprotkb:A4D2I9|uniprotkb:B4DEM2|uniprotkb:C9J7P1|uniprotkb:B4DDP6|intact:EBI-28973053|ensembl:ENSP00000411701 psi-mi:q6znl61(display_long)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym) psi-mi:dbnl_human(display_long)|uniprotkb:Drebrin-F(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Cervical SH3P7(gene name synonym)|uniprotkb:HPK1-interacting protein of 55 kDa(gene name synonym)|uniprotkb:Cervical mucin-associated protein(gene name synonym)|uniprotkb:DBNL(gene name)|psi-mi:DBNL(display_short)|uniprotkb:CMAP(gene name synonym)|uniprotkb:SH3P7(gene name synonym)|uniprotkb:PP5423(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412111|imex:IM-26436-148 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZNL6-1(isoform-parent) refseq:NP_001271242.1|refseq:NP_001271244.1|refseq:NP_001014436.1|refseq:NP_001116428.1|refseq:NP_054782.2|ensembl:ENST00000440166|ensembl:ENSP00000415173|ensembl:ENSP00000411701|ensembl:ENST00000456905|ensembl:ENSP00000416421|ensembl:ENST00000468694|ensembl:ENSP00000417653|ensembl:ENST00000490734|ensembl:ENSP00000417749|ensembl:ENST00000494774|ensembl:ENSP00000419992|ensembl:ENSG00000136279(gene)|ensembl:ENST00000448521(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923|interpro:IPR035717|interpro:IPR036028|mint:Q9UJU6|rcsb pdb:1X67|reactome:R-HSA-264870|reactome:R-HSA-6794361|reactome:R-HSA-6798695 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606 rogid:OOa7vGOHVCiCKA9Wt0YUYGR5cu09606 rigid:Cgclm0SwUx2gR3ne74HyQS4N5cA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNL6-1 uniprotkb:P84077 intact:EBI-25412104 intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980 psi-mi:q6znl61(display_long)|uniprotkb:FGD5(gene name)|psi-mi:FGD5(display_short)|uniprotkb:ZFYVE23(gene name synonym) psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412111|imex:IM-26436-148 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZNL6-1(isoform-parent) refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:42YG8lHD7Cafij/trgaNJ1ougwk9606 rogid:zray9asm6VonxpuJpv0dRBspPt89606 rigid:Cgclm0SwUx2gR3ne74HyQS4N5cA false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q8WXF1 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:P00747 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q9ULC4 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-716076|intact:EBI-1048747|uniprotkb:Q502X6|uniprotkb:B4DGY2|ensembl:ENSP00000360367|ensembl:ENSP00000500508 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:mcts1_human(display_long)|uniprotkb:MCTS1(gene name)|psi-mi:MCTS1(display_short)|uniprotkb:MCT1(gene name synonym)|uniprotkb:Multiple copies T-cell malignancies(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_001131026.1|refseq:NP_054779.1|ensembl:ENSG00000232119(gene)|ensembl:ENSG00000288295(gene)|ensembl:ENST00000371317(transcript)|ensembl:ENST00000673335(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0040008"(regulation of growth)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002478(PUA)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR015947(PUA-like)|interpro:IPR016437(Translation machinery-associated RNA binding protein, predicted)|interpro:IPR041366|rcsb pdb:3R90|rcsb pdb:5ONS|rcsb pdb:5VYC|rcsb pdb:6MS4 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:g630bQeYIEobBeB8zTPwIiGlPys9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:P25490 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:O94842 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q6I9Y2 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-716286|uniprotkb:Q6P1L3|uniprotkb:Q8WUF2|uniprotkb:Q9H5H0|ensembl:ENSP00000295899 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:thoc7_human(display_long)|uniprotkb:Functional spliceosome-associated protein 24(gene name synonym)|uniprotkb:hTREX30(gene name synonym)|uniprotkb:NIF3L1BP1(gene name synonym)|uniprotkb:Ngg1-interacting factor 3-like protein 1-binding protein 1(gene name synonym)|uniprotkb:THOC7(gene name)|psi-mi:THOC7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_001272333.1|refseq:NP_079351.2|ensembl:ENSG00000163634(gene)|ensembl:ENST00000295899(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR008501(Protein of unknown function DUF783)|mint:Q6I9Y2|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:15M7nouxNuzlKZPawajrahz0LAY9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q86W42 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-2880668|ensembl:ENSP00000326531|uniprotkb:Q8NBR1|uniprotkb:B2RA85|uniprotkb:Q9BTV9 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:thoc6_human(display_long)|uniprotkb:THOC6(gene name)|psi-mi:THOC6(display_short)|uniprotkb:WDR58(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 35(gene name synonym)|uniprotkb:WD repeat-containing protein 58(gene name synonym)|uniprotkb:PSEC0006(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) ensembl:ENSG00000131652(gene)|ensembl:ENST00000326266(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR042626|mint:Q86W42|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_001135822.1|refseq:NP_077315.2|refseq:NP_001334632.1|refseq:NP_001334633.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:mmpU10uiZc1+MK8ntLeD+GCVIOM9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q9BSH4 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-747797|uniprotkb:Q8N3N6|uniprotkb:Q9UI60|uniprotkb:B2RD21|ensembl:ENSP00000258975 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:taco1_human(display_long)|uniprotkb:PRO0477(orf name)|uniprotkb:TACO1(gene name)|psi-mi:TACO1(display_short)|uniprotkb:CCDC44(gene name synonym)|uniprotkb:Translational activator of mitochondrially-encoded cytochrome c oxidase I(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 44(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_057444.2|ensembl:ENSG00000136463(gene)|ensembl:ENST00000258975(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0019843"(rRNA binding)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0061743"(motor learning)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR026564|interpro:IPR029072|mint:Q9BSH4|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:c/tu89NvCs3Kt8qO8e5F6hrywBo9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q9Y3B4 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-1046261|ensembl:ENSP00000233468|uniprotkb:Q53TM1 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:sf3b6_human(display_long)|uniprotkb:SF3B6(gene name)|psi-mi:SF3B6(display_short)|uniprotkb:Pre-mRNA branch site protein p14(gene name synonym)|uniprotkb:SAP14(gene name synonym)|uniprotkb:SF3B14(gene name synonym)|uniprotkb:SF3B14A(gene name synonym)|uniprotkb:SF3b 14 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein, 14-kDa(gene name synonym)|uniprotkb:Splicing factor 3b, subunit 6, 14kDa(gene name synonym)|uniprotkb:CGI-110(orf name)|uniprotkb:HSPC175(orf name)|uniprotkb:HT006(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) ensembl:ENST00000233468(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000115128(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034150|interpro:IPR035979|mint:Q9Y3B4|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:3LQV|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_057131.1|dip:DIP-44132N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:7mhaXkmVqjfJGPdX1UDM+kN4vNI9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:P49756 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q9NXS2 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-1052839|uniprotkb:Q53HE4|uniprotkb:Q96F74|ensembl:ENSP00000012049 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:qpctl_human(display_long)|uniprotkb:Golgi-resident glutaminyl-peptide cyclotransferase(gene name synonym)|uniprotkb:isoQC(gene name synonym)|uniprotkb:QPCTL(gene name)|psi-mi:QPCTL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_001156849.1|refseq:NP_060129.2|ensembl:ENSG00000011478(gene)|ensembl:ENST00000012049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016603"(glutaminyl-peptide cyclotransferase activity)|go:"GO:0017186"(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)|interpro:IPR037457|interpro:IPR040234|rcsb pdb:3PB4|rcsb pdb:3PB6|rcsb pdb:3PB7|rcsb pdb:3PB8|rcsb pdb:3PB9|interpro:IPR007484(Peptidase M28) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:J4CsQuJYRh/8S2KDQQGzZh3Mra89606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:P32322 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-848624|uniprotkb:B4DMU0|uniprotkb:Q6FHI4|uniprotkb:Q96DI6|uniprotkb:A6NFM2|uniprotkb:Q9HBQ4|ensembl:ENSP00000328858|ensembl:ENSP00000479793 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:p5cr1_human(display_long)|uniprotkb:PYCR1(gene name)|psi-mi:PYCR1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_008838.2|refseq:XP_011521885.1|refseq:XP_011521886.1|refseq:NP_001269209.1|refseq:NP_001269210.1|refseq:XP_005256438.1|refseq:NP_722546.1|ensembl:ENSG00000183010(gene)|ensembl:ENST00000329875(transcript)|ensembl:ENST00000619204(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:P32322|rcsb pdb:2GER|rcsb pdb:2GR9|rcsb pdb:2GRA|rcsb pdb:2IZZ|rcsb pdb:5UAT|rcsb pdb:5UAU|rcsb pdb:5UAV|rcsb pdb:5UAW|rcsb pdb:5UAX|rcsb pdb:6XOZ|rcsb pdb:6XP0|rcsb pdb:6XP1|rcsb pdb:6XP2|rcsb pdb:6XP3|reactome:R-HSA-8964539 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:+hos1FhDb7QofDBHXEBGlWxv+z09606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q6P5Z2 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-1384335|uniprotkb:Q9UM03|ensembl:ENSP00000291906 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:pkn3_human(display_long)|uniprotkb:PKNBETA(gene name synonym)|uniprotkb:Protein kinase PKN-beta(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 3(gene name synonym)|uniprotkb:PKN3(gene name)|psi-mi:PKN3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_037487.2|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000160447(gene)|ensembl:ENST00000291906(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:VkdWW9BW24I/9AWyh6wP5u1MRCA9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:O43809 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q6P1L8 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-1043903|ensembl:ENSP00000361084|uniprotkb:Q96Q72|uniprotkb:B2R575 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:rm14_human(display_long)|uniprotkb:MRPL14(gene name)|psi-mi:MRPL14(display_short)|uniprotkb:RPML32(gene name synonym)|uniprotkb:MRPL32(gene name synonym)|uniprotkb:39S ribosomal protein L32, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein uL14m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) ensembl:ENSG00000180992(gene)|ensembl:ENST00000372014(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR036853|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_115487.2|refseq:NP_001305696.1|refseq:NP_001305697.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:Iwh7qhYEwAsJk6e9hA2IiCcvey09606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q15555 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-739717|uniprotkb:Q9UQ33|uniprotkb:B2RE21|uniprotkb:B3KR39|uniprotkb:B7Z2L3|uniprotkb:E9PHR3|uniprotkb:F5H1V8|uniprotkb:B4DJV4|uniprotkb:G5E9I6|ensembl:ENSP00000300249 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:mare2_human(display_long)|uniprotkb:MAPRE2(gene name)|psi-mi:MAPRE2(display_short)|uniprotkb:RP1(gene name synonym)|uniprotkb:APC-binding protein EB2(gene name synonym)|uniprotkb:End-binding protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_055083.1|refseq:NP_001137298.1|refseq:NP_001137299.1|refseq:NP_001243349.1|ensembl:ENSG00000166974(gene)|ensembl:ENST00000300249(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042802"(identical protein binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1904825"(protein localization to microtubule plus-end)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027735|interpro:IPR036133|interpro:IPR036872 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:rQ5GWouV1PQve0kbnqZy9x9bTMA9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q9Y4Z0 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-372521|ensembl:ENSP00000469468 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:lsm4_human(display_long)|uniprotkb:Glycine-rich protein(gene name synonym)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_036453.1|ensembl:ENSG00000130520(gene)|ensembl:ENST00000593829(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0043005"(neuron projection)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|dip:DIP-31209N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:FlaQveuBbixGvfX47pCm26xscT09606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q92979 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-718638|uniprotkb:O00675|uniprotkb:O00726|ensembl:ENSP00000470560 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:nep1_human(display_long)|uniprotkb:Nucleolar protein EMG1 homolog(gene name synonym)|uniprotkb:Protein C2f(gene name synonym)|uniprotkb:EMG1(gene name)|psi-mi:EMG1(display_short)|uniprotkb:C2F(gene name synonym)|uniprotkb:18S rRNA Psi1248 methyltransferase(gene name synonym)|uniprotkb:Ribosome biogenesis protein NEP1(gene name synonym)|uniprotkb:"18S rRNA (pseudouridine(1248)-N1)-methyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_006322.4|refseq:NP_001306978.1|ensembl:ENSG00000126749(gene)|ensembl:ENST00000599672(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0017126"(nucleologenesis)|go:"GO:0019843"(rRNA binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070037"("rRNA (pseudouridine) methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|interpro:IPR005304(Suppressor Mra1)|interpro:IPR029026|interpro:IPR029028|mint:Q92979|rcsb pdb:5FAI|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:zIhyWwzd8MtIUn9JyWbXPHeGpF49606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:P49674 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:evdzz03ba4MFWavN9xRae/Wxwio9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:P48730 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-751621|uniprotkb:Q96KZ6|uniprotkb:Q9BTN5|uniprotkb:A2I2P2|ensembl:ENSP00000324464 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:kc1d_human(display_long)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_001884.2|refseq:NP_620693.1|dip:DIP-39735N|ensembl:ENSG00000141551(gene)|ensembl:ENST00000314028(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48730|rcsb pdb:3UYS|rcsb pdb:3UYT|rcsb pdb:3UZP|rcsb pdb:4HGT|rcsb pdb:4HNF|rcsb pdb:4KB8|rcsb pdb:4KBA|rcsb pdb:4KBC|rcsb pdb:4KBK|rcsb pdb:4TN6|rcsb pdb:4TW9|rcsb pdb:4TWC|rcsb pdb:5IH4|rcsb pdb:5IH5|rcsb pdb:5IH6|rcsb pdb:5MQV|rcsb pdb:5OKT|rcsb pdb:5W4W|rcsb pdb:6F1W|rcsb pdb:6F26|rcsb pdb:6GZM|rcsb pdb:6HMP|rcsb pdb:6HMR|rcsb pdb:6PXN|rcsb pdb:6PXO|rcsb pdb:6PXP|rcsb pdb:6RCG|rcsb pdb:6RCH|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-204005|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-400253|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:Rz5aON17Bfduv29izmgHa/FR1/49606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:O95639 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-725860|uniprotkb:Q86TF8|uniprotkb:Q9BTW6|uniprotkb:Q6FGE6|uniprotkb:D6W5S8|ensembl:ENSP00000292476 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:cpsf4_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 30 kDa subunit(gene name synonym)|uniprotkb:NS1 effector domain-binding protein 1(gene name synonym)|uniprotkb:No arches homolog(gene name synonym)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short)|uniprotkb:CPSF30(gene name synonym)|uniprotkb:NAR(gene name synonym)|uniprotkb:NEB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_001075028.1|refseq:NP_006684.1|refseq:NP_001305089.1|refseq:NP_001305090.1|refseq:NP_001305091.1|ensembl:ENSG00000160917(gene)|ensembl:ENST00000292476(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036855|interpro:IPR036875|interpro:IPR041686|mint:O95639|rcsb pdb:2D9N|rcsb pdb:2RHK|rcsb pdb:6DNH|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-168315|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-48675N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:CTNuFmbdKiPNvBJPEHoLi7WvoYM9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:P00918 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-724062|ensembl:ENSP00000285379|uniprotkb:Q6FI12|uniprotkb:Q96ET9|uniprotkb:B2R7G8 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:cah2_human(display_long)|uniprotkb:Carbonic anhydrase II(gene name synonym)|uniprotkb:Carbonate dehydratase II(gene name synonym)|uniprotkb:Carbonic anhydrase C(gene name synonym)|uniprotkb:CA2(gene name)|psi-mi:CA2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_000058.1|rcsb pdb:5YUI|rcsb pdb:5YUJ|rcsb pdb:5U0G|rcsb pdb:5YUK|rcsb pdb:5ZXW|rcsb pdb:6B4D|rcsb pdb:6B59|rcsb pdb:5ULN|rcsb pdb:6B5A|rcsb pdb:6BBS|rcsb pdb:6BC9|rcsb pdb:6BCC|rcsb pdb:6C7W|rcsb pdb:6C7X|rcsb pdb:6CA2|rcsb pdb:6CEH|rcsb pdb:6CJV|rcsb pdb:6D1L|rcsb pdb:6D1M|rcsb pdb:5UMC|rcsb pdb:5VGY|rcsb pdb:6E8P|rcsb pdb:6E8X|rcsb pdb:6E91|rcsb pdb:6E92|rcsb pdb:6EBE|rcsb pdb:6ECZ|rcsb pdb:6EDA|rcsb pdb:6EEA|rcsb pdb:6EEH|rcsb pdb:6EEO|rcsb pdb:6EQU|rcsb pdb:5W8B|rcsb pdb:6FJI|rcsb pdb:5WEX|rcsb pdb:6FJJ|rcsb pdb:6G3Q|rcsb pdb:6G6T|rcsb pdb:6GCY|rcsb pdb:6GDC|rcsb pdb:6GM9|rcsb pdb:5WG7|rcsb pdb:5WGP|rcsb pdb:5WLR|rcsb pdb:6GOT|rcsb pdb:6GXB|rcsb pdb:5WLT|rcsb pdb:5WLU|rcsb pdb:5WLV|rcsb pdb:5Y2R|rcsb pdb:5Y2S|rcsb pdb:6GXE|rcsb pdb:6H29|rcsb pdb:6H2Z|rcsb pdb:6H33|rcsb pdb:6H34|rcsb pdb:6H3Q|rcsb pdb:6H6S|rcsb pdb:6HD2|rcsb pdb:1BV3|rcsb pdb:1CA2|rcsb pdb:1CA3|rcsb pdb:1CAH|rcsb pdb:1CAI|rcsb pdb:1CAJ|rcsb pdb:1CAK|rcsb pdb:1CAL|rcsb pdb:1CAM|rcsb pdb:1CAN|rcsb pdb:1CAO|rcsb pdb:1CAY|rcsb pdb:1CAZ|rcsb pdb:1CCS|rcsb pdb:1CCT|rcsb pdb:1CCU|rcsb pdb:1CIL|rcsb pdb:1CIM|rcsb pdb:1CIN|rcsb pdb:1CNB|rcsb pdb:1CNC|rcsb pdb:1CNG|rcsb pdb:1CNH|rcsb pdb:1CNI|rcsb pdb:1CNJ|rcsb pdb:1BNW|rcsb pdb:1CNK|rcsb pdb:1CNW|rcsb pdb:1CNX|rcsb pdb:1CNY|rcsb pdb:1CRA|rcsb pdb:1CVA|rcsb pdb:1CVB|rcsb pdb:1IF4|rcsb pdb:1IF5|rcsb pdb:1IF6|rcsb pdb:1IF7|rcsb pdb:1IF8|rcsb pdb:1IF9|rcsb pdb:1KWQ|rcsb pdb:1I9Q|rcsb pdb:1KWR|rcsb pdb:1LG5|rcsb pdb:1LG6|rcsb pdb:1LGD|rcsb pdb:1LUG|rcsb pdb:1LZV|rcsb pdb:1MOO|rcsb pdb:1MUA|rcsb pdb:1OKL|rcsb pdb:1OKM|rcsb pdb:1OKN|rcsb pdb:1OQ5|rcsb pdb:1RAY|rcsb pdb:1RAZ|rcsb pdb:1RZA|rcsb pdb:1RZB|rcsb pdb:1RZC|rcsb pdb:1RZD|rcsb pdb:1RZE|rcsb pdb:1T9N|rcsb pdb:1TB0|rcsb pdb:1TBT|rcsb pdb:1TE3|rcsb pdb:1TEQ|rcsb pdb:1TEU|rcsb pdb:6HR3|rcsb pdb:6HX5|rcsb pdb:6HXD|rcsb pdb:6HZX|rcsb pdb:6I0W|rcsb pdb:6I1U|rcsb pdb:6I2F|rcsb pdb:6I3E|rcsb pdb:6IC2|rcsb pdb:6KLZ|rcsb pdb:6KM0|rcsb pdb:6KM1|rcsb pdb:6KM2|rcsb pdb:6KM3|rcsb pdb:6KM4|rcsb pdb:6KM5|rcsb pdb:6KM6|rcsb pdb:6LUU|rcsb pdb:6LUV|rcsb pdb:6LUW|rcsb pdb:6LUX|rcsb pdb:6LUY|rcsb pdb:6LUZ|rcsb pdb:6LV1|rcsb pdb:6LV2|rcsb pdb:6LV3|rcsb pdb:6LV4|rcsb pdb:6LV5|rcsb pdb:6LV6|rcsb pdb:6LV7|rcsb pdb:6LV8|rcsb pdb:6LV9|rcsb pdb:6HQX|rcsb pdb:6LVA|rcsb pdb:6MBV|rcsb pdb:6MBY|rcsb pdb:6NLV|rcsb pdb:6NM0|rcsb pdb:6ODZ|rcsb pdb:6OE0|rcsb pdb:6OE1|rcsb pdb:6OTI|rcsb pdb:6OTK|rcsb pdb:6OTM|rcsb pdb:6OTO|rcsb pdb:6OTP|rcsb pdb:6OTQ|rcsb pdb:1CVC|rcsb pdb:1CVD|rcsb pdb:1CVE|rcsb pdb:1G46|rcsb pdb:1G48|rcsb pdb:1CVF|rcsb pdb:1CVH|rcsb pdb:1DCA|rcsb pdb:1DCB|rcsb pdb:1EOU|rcsb pdb:1F2W|rcsb pdb:1FQL|rcsb pdb:1FQM|rcsb pdb:1FQN|rcsb pdb:1FQR|rcsb pdb:1FR4|rcsb pdb:1FR7|rcsb pdb:1FSN|rcsb pdb:1FSQ|rcsb pdb:1FSR|rcsb pdb:1G0E|rcsb pdb:1G0F|rcsb pdb:1G1D|rcsb pdb:1G3Z|rcsb pdb:1G45|rcsb pdb:6OUD|rcsb pdb:6OUE|rcsb pdb:6OUF|rcsb pdb:6OUH|rcsb pdb:6OUI|rcsb pdb:6OUJ|rcsb pdb:6OUK|rcsb pdb:6OUM|rcsb pdb:6PDV|rcsb pdb:6PEA|rcsb pdb:6PGX|rcsb pdb:6Q3O|rcsb pdb:6Q9T|rcsb pdb:6QEB|rcsb pdb:6QL1|rcsb pdb:6QL2|rcsb pdb:6QL3|rcsb pdb:6OUB|rcsb pdb:6R6F|rcsb pdb:6R6J|rcsb pdb:6RFH|rcsb pdb:6RG3|rcsb pdb:6RG4|rcsb pdb:6RG5|rcsb pdb:6RH4|rcsb pdb:6RHJ|rcsb pdb:6RHK|rcsb pdb:6RIG|rcsb pdb:6RIT|rcsb pdb:6RJJ|rcsb pdb:6RKN|rcsb pdb:6RL9|rcsb pdb:6RM1|rcsb pdb:6RMP|rcsb pdb:6RMX|rcsb pdb:6RMY|rcsb pdb:6RNP|rcsb pdb:6ROB|rcsb pdb:6ROE|rcsb pdb:6ROF|rcsb pdb:3TVO|rcsb pdb:3U3A|rcsb pdb:3U45|rcsb pdb:3U47|rcsb pdb:3U7C|rcsb pdb:3V2J|rcsb pdb:3TVN|rcsb pdb:3V2M|rcsb pdb:3V3F|rcsb pdb:3V3G|rcsb pdb:3V3H|rcsb pdb:3V3I|rcsb pdb:3V3J|rcsb pdb:3V5G|rcsb pdb:3V7X|rcsb pdb:3VBD|rcsb pdb:3ZP9|rcsb pdb:4BCW|rcsb pdb:4BF1|rcsb pdb:4BF6|rcsb pdb:4CA2|rcsb pdb:4CAC|rcsb pdb:4CQ0|rcsb pdb:4DZ7|rcsb pdb:4DZ9|rcsb pdb:4E3D|rcsb pdb:6RQI|rcsb pdb:6T5C|rcsb pdb:6T7U|rcsb pdb:6T81|rcsb pdb:6T9Z|rcsb pdb:6U4Q|rcsb pdb:6U4T|rcsb pdb:6UFB|rcsb pdb:6UFC|rcsb pdb:6UFD|rcsb pdb:6UGN|rcsb pdb:6UGO|rcsb pdb:6UGP|rcsb pdb:6UGQ|rcsb pdb:6UGR|rcsb pdb:6UGZ|rcsb pdb:6UH0|rcsb pdb:6UX1|rcsb pdb:6UZU|rcsb pdb:6VJ3|rcsb pdb:6VKG|rcsb pdb:1TG3|rcsb pdb:1TG9|rcsb pdb:1TH9|rcsb pdb:1THK|rcsb pdb:1TTM|rcsb pdb:1UGA|rcsb pdb:1UGB|rcsb pdb:1UGC|rcsb pdb:1UGD|rcsb pdb:1UGE|rcsb pdb:1UGF|rcsb pdb:1UGG|rcsb pdb:1XEG|rcsb pdb:1XEV|rcsb pdb:1XPZ|rcsb pdb:1XQ0|rcsb pdb:1YDA|rcsb pdb:1YDB|rcsb pdb:1YDC|rcsb pdb:1YDD|rcsb pdb:1YO0|rcsb pdb:1YO1|rcsb pdb:1YO2|rcsb pdb:1Z9Y|rcsb pdb:1ZE8|rcsb pdb:1ZFK|rcsb pdb:1ZFQ|rcsb pdb:1ZGE|rcsb pdb:4E3F|rcsb pdb:4E3G|rcsb pdb:4E3H|rcsb pdb:4E49|rcsb pdb:4E4A|rcsb pdb:4E5Q|rcsb pdb:4FIK|rcsb pdb:4FL7|rcsb pdb:4FPT|rcsb pdb:4FRC|rcsb pdb:4FU5|rcsb pdb:4FVN|rcsb pdb:4FVO|rcsb pdb:4G0C|rcsb pdb:4GL1|rcsb pdb:4HBA|rcsb pdb:4HEW|rcsb pdb:4HEY|rcsb pdb:4HEZ|rcsb pdb:4HF3|rcsb pdb:4HT0|rcsb pdb:4IDR|rcsb pdb:4ILX|rcsb pdb:4ITO|rcsb pdb:4ITP|rcsb pdb:4IWZ|rcsb pdb:4JS6|rcsb pdb:4JSA|rcsb pdb:4JSS|rcsb pdb:4JSW|rcsb pdb:4JSZ|rcsb pdb:4K0S|rcsb pdb:4K0T|rcsb pdb:4K0Z|rcsb pdb:4K13|rcsb pdb:4K1Q|rcsb pdb:4KAP|rcsb pdb:4KNI|rcsb pdb:4KNJ|rcsb pdb:4KUV|rcsb pdb:4KUW|rcsb pdb:4KUY|rcsb pdb:4KV0|rcsb pdb:4L5U|rcsb pdb:4L5V|rcsb pdb:4L5W|rcsb pdb:4LHI|rcsb pdb:4LP6|rcsb pdb:4M2R|rcsb pdb:4M2U|rcsb pdb:4M2V|rcsb pdb:4M2W|rcsb pdb:4MDG|rcsb pdb:4MDL|rcsb pdb:4MDM|rcsb pdb:4MLT|rcsb pdb:4MLX|rcsb pdb:1ZGF|rcsb pdb:1ZH9|rcsb pdb:1ZSA|rcsb pdb:1ZSB|rcsb pdb:1ZSC|rcsb pdb:2ABE|rcsb pdb:2AW1|rcsb pdb:2AX2|rcsb pdb:2CA2|rcsb pdb:2CBA|rcsb pdb:2CBB|rcsb pdb:2CBC|rcsb pdb:2CBD|rcsb pdb:2CBE|rcsb pdb:2EU2|rcsb pdb:2EU3|rcsb pdb:2EZ7|rcsb pdb:2F14|rcsb pdb:2FMG|rcsb pdb:2FMZ|rcsb pdb:2FNK|rcsb pdb:2FNM|rcsb pdb:2FNN|rcsb pdb:2HOC|rcsb pdb:2FOQ|rcsb pdb:2FOS|rcsb pdb:2ILI|rcsb pdb:2FOU|rcsb pdb:2NNG|rcsb pdb:2NNO|rcsb pdb:2NNS|rcsb pdb:2FOV|rcsb pdb:2GD8|rcsb pdb:2GEH|rcsb pdb:2NNV|rcsb pdb:2NWO|rcsb pdb:2NWP|rcsb pdb:2NWY|rcsb pdb:2NWZ|rcsb pdb:2H15|rcsb pdb:2NXR|rcsb pdb:2NXS|rcsb pdb:2NXT|rcsb pdb:2O4Z|rcsb pdb:2OSF|rcsb pdb:2OSM|rcsb pdb:2POU|rcsb pdb:2POV|rcsb pdb:2POW|rcsb pdb:2H4N|rcsb pdb:2Q1B|rcsb pdb:2Q1Q|rcsb pdb:2Q38|rcsb pdb:2QO8|rcsb pdb:2QOA|rcsb pdb:2QP6|rcsb pdb:2VVA|rcsb pdb:2VVB|rcsb pdb:2HD6|rcsb pdb:2HKK|rcsb pdb:2WD2|rcsb pdb:2WD3|rcsb pdb:2HL4|rcsb pdb:2HNC|rcsb pdb:2WEG|rcsb pdb:2WEH|rcsb pdb:2WEJ|rcsb pdb:2WEO|rcsb pdb:4MTY|rcsb pdb:4N0X|rcsb pdb:4N16|rcsb pdb:4PQ7|rcsb pdb:4PXX|rcsb pdb:4PYX|rcsb pdb:4PYY|rcsb pdb:4PZH|rcsb pdb:4Q06|rcsb pdb:4Q07|rcsb pdb:4Q08|rcsb pdb:4Q09|rcsb pdb:4Q49|rcsb pdb:4Q6D|rcsb pdb:4Q6E|rcsb pdb:4Q78|rcsb pdb:4Q7P|rcsb pdb:4Q7S|rcsb pdb:4Q7V|rcsb pdb:4Q7W|rcsb pdb:4Q81|rcsb pdb:4Q83|rcsb pdb:4Q87|rcsb pdb:4Q8X|rcsb pdb:4Q8Y|rcsb pdb:4Q8Z|rcsb pdb:4Q90|rcsb pdb:4Q99|rcsb pdb:4Q9Y|rcsb pdb:4QEF|rcsb pdb:4QIY|rcsb pdb:4QJM|rcsb pdb:4QK1|rcsb pdb:4QK2|rcsb pdb:4QK3|rcsb pdb:4QSA|rcsb pdb:4QSB|rcsb pdb:4QSI|rcsb pdb:4QTL|rcsb pdb:4QY3|rcsb pdb:4R59|rcsb pdb:4R5A|rcsb pdb:4R5B|rcsb pdb:4RFC|rcsb pdb:4RFD|rcsb pdb:4RH2|rcsb pdb:4RIU|rcsb pdb:4RIV|rcsb pdb:4RN4|rcsb pdb:4RUX|rcsb pdb:4RUY|rcsb pdb:4RUZ|rcsb pdb:4WL4|rcsb pdb:4WW6|rcsb pdb:4MO8|rcsb pdb:4XE1|rcsb pdb:4Y0J|rcsb pdb:4YGJ|rcsb pdb:4YGK|rcsb pdb:4YGL|rcsb pdb:4YGN|rcsb pdb:4YVY|rcsb pdb:4YWP|rcsb pdb:4YX4|rcsb pdb:4YXI|rcsb pdb:4YXO|rcsb pdb:6RRI|rcsb pdb:6RS5|rcsb pdb:6RSZ|rcsb pdb:6RVF|rcsb pdb:6RVK|rcsb pdb:6RVL|rcsb pdb:6RW1|rcsb pdb:6RZX|rcsb pdb:6S03|rcsb pdb:6S9G|rcsb pdb:6S9Z|rcsb pdb:6SAC|rcsb pdb:6SAS|rcsb pdb:6SAY|rcsb pdb:6SB7|rcsb pdb:6SBH|rcsb pdb:6SBL|rcsb pdb:6SBM|rcsb pdb:6SD7|rcsb pdb:6SDH|rcsb pdb:6SDI|rcsb pdb:6SDJ|rcsb pdb:6SDL|rcsb pdb:6SDS|rcsb pdb:6SEY|rcsb pdb:6RRG|rcsb pdb:6SFQ|rcsb pdb:6SFU|rcsb pdb:6SG0|rcsb pdb:6SG6|rcsb pdb:6SX9|rcsb pdb:6SYB|rcsb pdb:6SYS|rcsb pdb:6T4N|rcsb pdb:6T4O|rcsb pdb:6T4P|rcsb pdb:2X7S|rcsb pdb:2X7T|rcsb pdb:2X7U|rcsb pdb:3B4F|rcsb pdb:3BET|rcsb pdb:3BL0|rcsb pdb:3BL1|rcsb pdb:3C7P|rcsb pdb:3CA2|rcsb pdb:3CAJ|rcsb pdb:3CYU|rcsb pdb:3D8W|rcsb pdb:3D92|rcsb pdb:3D93|rcsb pdb:3D9Z|rcsb pdb:3DAZ|rcsb pdb:3DBU|rcsb pdb:3DC3|rcsb pdb:3DC9|rcsb pdb:3DCC|rcsb pdb:3DCS|rcsb pdb:3DCW|rcsb pdb:3DD0|rcsb pdb:3DD8|rcsb pdb:3DV7|rcsb pdb:3DVB|rcsb pdb:3DVC|rcsb pdb:3DVD|rcsb pdb:3EFI|rcsb pdb:3EFT|rcsb pdb:4YYT|rcsb pdb:4Z0Q|rcsb pdb:4Z1E|rcsb pdb:4Z1J|rcsb pdb:4Z1K|rcsb pdb:4Z1N|rcsb pdb:4ZAO|rcsb pdb:4ZWI|rcsb pdb:4ZWX|rcsb pdb:4ZWY|rcsb pdb:4ZWZ|rcsb pdb:4ZX0|rcsb pdb:4ZX1|rcsb pdb:5A6H|rcsb pdb:5AMD|rcsb pdb:5AMG|rcsb pdb:5AML|rcsb pdb:5BNL|rcsb pdb:5BRU|rcsb pdb:5BRV|rcsb pdb:5BRW|rcsb pdb:5BYI|rcsb pdb:5C8I|rcsb pdb:5CA2|rcsb pdb:5CAC|rcsb pdb:5CLU|rcsb pdb:5DOG|rcsb pdb:5DOH|rcsb pdb:5DRS|rcsb pdb:5DSK|rcsb pdb:5DSL|rcsb pdb:5DSM|rcsb pdb:5DSO|rcsb pdb:5DSP|rcsb pdb:4YXU|rcsb pdb:5DSQ|rcsb pdb:5DSR|rcsb pdb:5E28|rcsb pdb:5E2K|rcsb pdb:5E2R|rcsb pdb:5E2S|rcsb pdb:5EH5|rcsb pdb:5EH7|rcsb pdb:5EH8|rcsb pdb:5EHE|rcsb pdb:5EHV|rcsb pdb:5EHW|rcsb pdb:5EIJ|rcsb pdb:5EKH|rcsb pdb:3F4X|rcsb pdb:3F8E|rcsb pdb:3FFP|rcsb pdb:3GZ0|rcsb pdb:3HFP|rcsb pdb:3HKN|rcsb pdb:3HKQ|rcsb pdb:3HKT|rcsb pdb:3HKU|rcsb pdb:3HLJ|rcsb pdb:3HS4|rcsb pdb:3IBI|rcsb pdb:3IBL|rcsb pdb:3IBN|rcsb pdb:3IBU|rcsb pdb:3IEO|rcsb pdb:3IGP|rcsb pdb:3K2F|rcsb pdb:3K34|rcsb pdb:3K7K|rcsb pdb:3KIG|rcsb pdb:3KKX|rcsb pdb:3KNE|rcsb pdb:3KOI|rcsb pdb:3KOK|rcsb pdb:3KON|rcsb pdb:3KS3|rcsb pdb:3KWA|rcsb pdb:3L14|rcsb pdb:3M04|rcsb pdb:3M14|rcsb pdb:3M1J|rcsb pdb:3M1K|rcsb pdb:3M1Q|rcsb pdb:3M1W|rcsb pdb:3M2N|rcsb pdb:3M2X|rcsb pdb:3M2Y|rcsb pdb:3M2Z|rcsb pdb:3M3X|rcsb pdb:3M40|rcsb pdb:3M5E|rcsb pdb:3M5S|rcsb pdb:3M5T|rcsb pdb:3M67|rcsb pdb:3M96|rcsb pdb:3M98|rcsb pdb:3MHC|rcsb pdb:3MHI|rcsb pdb:3MHL|rcsb pdb:3MHM|rcsb pdb:3MHO|rcsb pdb:3ML2|rcsb pdb:3MMF|rcsb pdb:3MNA|rcsb pdb:3MNH|rcsb pdb:3MNI|rcsb pdb:3MNJ|rcsb pdb:3MNK|rcsb pdb:3MNU|rcsb pdb:3MWO|rcsb pdb:3MYQ|rcsb pdb:3MZC|rcsb pdb:3N0N|rcsb pdb:3N2P|rcsb pdb:5EKM|rcsb pdb:5EOI|rcsb pdb:5FDC|rcsb pdb:5FDI|rcsb pdb:5FLO|rcsb pdb:5FLP|rcsb pdb:5FLQ|rcsb pdb:5FLR|rcsb pdb:5FLS|rcsb pdb:5FLT|rcsb pdb:5FNG|rcsb pdb:5FNH|rcsb pdb:5FNI|rcsb pdb:5FNJ|rcsb pdb:5FNK|rcsb pdb:5FNL|rcsb pdb:5FNM|rcsb pdb:5G01|rcsb pdb:5G03|rcsb pdb:5G0B|rcsb pdb:5G0C|rcsb pdb:5GMN|rcsb pdb:5J8Z|rcsb pdb:5EKJ|rcsb pdb:3N4B|rcsb pdb:3N3J|rcsb pdb:3NB5|rcsb pdb:3NI5|rcsb pdb:3NJ9|rcsb pdb:3OIK|rcsb pdb:3OIL|rcsb pdb:3OIM|rcsb pdb:3OKU|rcsb pdb:3OKV|rcsb pdb:3OY0|rcsb pdb:3OYQ|rcsb pdb:3OYS|rcsb pdb:3P3H|rcsb pdb:3P3J|rcsb pdb:3P44|rcsb pdb:3P4V|rcsb pdb:3P55|rcsb pdb:3P58|rcsb pdb:3P5A|rcsb pdb:3P5L|rcsb pdb:3PJJ|rcsb pdb:3PO6|rcsb pdb:5JE7|rcsb pdb:5JEG|rcsb pdb:5JEH|rcsb pdb:5JEP|rcsb pdb:5JES|rcsb pdb:5JG3|rcsb pdb:5JG5|rcsb pdb:5JGS|rcsb pdb:5JGT|rcsb pdb:5JMZ|rcsb pdb:5JN3|rcsb pdb:5JN7|rcsb pdb:5JQ0|rcsb pdb:5JQT|rcsb pdb:5L3O|rcsb pdb:5L6K|rcsb pdb:5L6T|rcsb pdb:5L70|rcsb pdb:5L9E|rcsb pdb:5JDV|rcsb pdb:5LJQ|rcsb pdb:5LJT|rcsb pdb:5LL4|rcsb pdb:5LL8|rcsb pdb:5LLC|rcsb pdb:5LLE|rcsb pdb:5LLG|rcsb pdb:5LLH|rcsb pdb:5LMD|rcsb pdb:5LVS|rcsb pdb:5M78|rcsb pdb:5MJN|rcsb pdb:5N0D|rcsb pdb:5N0E|rcsb pdb:5N1R|rcsb pdb:5N1S|rcsb pdb:5N24|rcsb pdb:5N25|rcsb pdb:5NEA|rcsb pdb:5NEE|rcsb pdb:5NXG|ensembl:ENSG00000104267(gene)|ensembl:ENST00000285379(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004064"(arylesterase activity)|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016836"(hydro-lyase activity)|go:"GO:0030424"(axon)|go:"GO:0032849"(positive regulation of cellular pH reduction)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043627"(response to estrogen)|go:"GO:0044070"(regulation of anion transport)|rcsb pdb:1G4O|rcsb pdb:1G52|rcsb pdb:1G53|rcsb pdb:1G54|rcsb pdb:1H4N|rcsb pdb:1H9N|rcsb pdb:1H9Q|rcsb pdb:1HCA|rcsb pdb:1G4J|rcsb pdb:1HEA|rcsb pdb:1HEB|rcsb pdb:1HEC|rcsb pdb:1HED|rcsb pdb:1HVA|rcsb pdb:1I8Z|rcsb pdb:1I90|rcsb pdb:1I91|rcsb pdb:1I9L|rcsb pdb:1I9M|rcsb pdb:1I9N|rcsb pdb:1I9O|rcsb pdb:1I9P|rcsb pdb:3QYK|rcsb pdb:3R16|rcsb pdb:3R17|rcsb pdb:3RG3|rcsb pdb:3RG4|rcsb pdb:3RGE|rcsb pdb:3RJ7|rcsb pdb:3RLD|rcsb pdb:3RYJ|rcsb pdb:3RYV|rcsb pdb:3RYX|rcsb pdb:3RYY|rcsb pdb:3RYZ|rcsb pdb:3RZ0|rcsb pdb:3RZ1|rcsb pdb:3PYK|rcsb pdb:3RZ5|rcsb pdb:3RZ7|rcsb pdb:3RZ8|rcsb pdb:3S71|rcsb pdb:3S72|rcsb pdb:3S73|rcsb pdb:3S74|rcsb pdb:3S75|rcsb pdb:3S76|rcsb pdb:3S77|rcsb pdb:3S78|rcsb pdb:3S8X|rcsb pdb:3S9T|rcsb pdb:3SAP|rcsb pdb:3SAX|rcsb pdb:3SBH|rcsb pdb:3SBI|rcsb pdb:3T5U|rcsb pdb:3T5Z|rcsb pdb:3T82|rcsb pdb:3T83|rcsb pdb:3T84|rcsb pdb:3T85|rcsb pdb:3TMJ|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR023561|interpro:IPR036398|mint:P00918|rcsb pdb:12CA|rcsb pdb:1A42|rcsb pdb:1AM6|rcsb pdb:1AVN|rcsb pdb:1BCD|rcsb pdb:1BIC|rcsb pdb:1BN1|rcsb pdb:1BN3|rcsb pdb:1BN4|rcsb pdb:1BNM|rcsb pdb:1BNN|rcsb pdb:1BNQ|rcsb pdb:1BNT|rcsb pdb:1BNU|rcsb pdb:1BNV|rcsb pdb:5NXI|rcsb pdb:5NY3|rcsb pdb:5NY6|rcsb pdb:5NYA|rcsb pdb:5O07|rcsb pdb:5OGN|rcsb pdb:5OGO|rcsb pdb:5OGP|rcsb pdb:5SZ0|rcsb pdb:5SZ1|rcsb pdb:5SZ2|rcsb pdb:5NXM|rcsb pdb:5NXO|rcsb pdb:5SZ3|rcsb pdb:5SZ4|rcsb pdb:5SZ5|rcsb pdb:5SZ6|rcsb pdb:5NXP|rcsb pdb:5SZ7|rcsb pdb:5T71|rcsb pdb:5T72|rcsb pdb:5T74|rcsb pdb:5T75|rcsb pdb:5TFX|rcsb pdb:5TH4|rcsb pdb:5THI|rcsb pdb:5THJ|rcsb pdb:5THN|rcsb pdb:5TI0|rcsb pdb:5TXY|rcsb pdb:5TY1|rcsb pdb:5TY8|rcsb pdb:5TY9|rcsb pdb:5NXV|rcsb pdb:5NXW|rcsb pdb:5NY1|rcsb pdb:5TYA|rcsb pdb:5U0D|rcsb pdb:5U0E|rcsb pdb:5U0F|rcsb pdb:6WKA|rcsb pdb:6WQ4|rcsb pdb:6WQ5|rcsb pdb:6WQ7|rcsb pdb:6WQ8|rcsb pdb:6WQ9|rcsb pdb:6XVH|rcsb pdb:6XWZ|rcsb pdb:6XXT|rcsb pdb:6YH4|rcsb pdb:6YH5|rcsb pdb:6YH6|rcsb pdb:6YH7|rcsb pdb:6YH8|rcsb pdb:6YH9|rcsb pdb:6YHA|rcsb pdb:6YHB|rcsb pdb:6YHC|rcsb pdb:6YJ3|rcsb pdb:6YKC|rcsb pdb:6YKH|rcsb pdb:6YMA|rcsb pdb:6YMB|rcsb pdb:6YO2|rcsb pdb:6YO4|rcsb pdb:6YO7|rcsb pdb:6YOI|rcsb pdb:6YOK|rcsb pdb:6YOL|rcsb pdb:6YPW|rcsb pdb:6YQT|rcsb pdb:6YQU|rcsb pdb:6YRI|rcsb pdb:6YZJ|rcsb pdb:6YZK|rcsb pdb:6YZL|rcsb pdb:6YZT|rcsb pdb:6YZU|rcsb pdb:6YZV|rcsb pdb:6YZM|rcsb pdb:6YZW|rcsb pdb:6YZX|rcsb pdb:6Z04|rcsb pdb:6ZR8|rcsb pdb:6YZN|rcsb pdb:6YZO|rcsb pdb:7BI5|rcsb pdb:7CA2|rcsb pdb:7JNR|rcsb pdb:7JNV|rcsb pdb:7JNW|rcsb pdb:7JNX|rcsb pdb:7JNZ|rcsb pdb:7JO0|rcsb pdb:7JO1|rcsb pdb:7JO2|rcsb pdb:7JO3|rcsb pdb:7JOB|rcsb pdb:7JOC|rcsb pdb:7K6I|rcsb pdb:7K6J|rcsb pdb:7K6K|rcsb pdb:7K6L|rcsb pdb:7K6T|rcsb pdb:7K6U|rcsb pdb:7K6X|rcsb pdb:7K6Z|rcsb pdb:8CA2|rcsb pdb:9CA2|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-1475029|rcsb pdb:6YZP|rcsb pdb:6YZQ|rcsb pdb:6YZR|rcsb pdb:6YZS - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:Er5rv/L2XS7uyrm/fPxFFsN+EsU9606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:Q9BU76 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNA1-1 uniprotkb:O96019 intact:EBI-25412129|ensembl:ENSP00000274498 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:q9una1-1(display_long)|uniprotkb:GTPase regulator associated with focal adhesion kinase(gene name synonym)|uniprotkb:Oligophrenin-1-like protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 26(gene name synonym)|uniprotkb:ARHGAP26(gene name)|psi-mi:ARHGAP26(display_short)|uniprotkb:GRAF(gene name synonym)|uniprotkb:KIAA0621(gene name synonym)|uniprotkb:OPHN1L(gene name synonym) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412137|imex:IM-26436-190 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1390913(isoform-parent)|ensembl:ENSG00000145819(gene)|ensembl:ENST00000274498(transcript) refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+nfOGTFJ2JEYzI7JSjRbNONtQq09606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 rigid:tf/dPbdJUY/+N5lNX91EgzDmVng false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A1L390-1 uniprotkb:P62273 intact:EBI-25412077 intact:EBI-1054121|uniprotkb:P30054|uniprotkb:A8MZ73|ensembl:ENSP00000245458|ensembl:ENSP00000495033 psi-mi:a1l3901(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:rs29_human(display_long)|uniprotkb:RPS29(gene name)|psi-mi:RPS29(display_short)|uniprotkb:Small ribosomal subunit protein uS14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412084|imex:IM-26436-110 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A1L390-1(isoform-parent) refseq:NP_001023.1|refseq:NP_001025172.1|ensembl:ENSG00000213741(gene)|ensembl:ENST00000245458(transcript)|ensembl:ENST00000556230(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR039744|interpro:IPR043140|mint:P62273|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+obep09w4klmkB8i13aA5FQW2609606 rogid:vMgvFs6gwidbpv837yH2u0sSIAU9606 rigid:7YqljFMCBTaxkOhmzUFuxNzKU0A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A1L390-1 uniprotkb:Q9UBW7 intact:EBI-25412077 intact:EBI-2797576|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904 psi-mi:a1l3901(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412084|imex:IM-26436-110 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A1L390-1(isoform-parent) refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904|refseq:XP_005266577.1|ensembl:ENSG00000121741(gene)|ensembl:ENST00000382871(transcript)|ensembl:ENST00000382874(transcript)|ensembl:ENST00000610343(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:XP_016876218.1|refseq:XP_011533526.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+obep09w4klmkB8i13aA5FQW2609606 rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606 rigid:7YqljFMCBTaxkOhmzUFuxNzKU0A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A1L390-1 uniprotkb:Q9NZR1 intact:EBI-25412077 intact:EBI-4289968|uniprotkb:B4DEW6|ensembl:ENSP00000249700 psi-mi:a1l3901(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:tmod2_human(display_long)|uniprotkb:TMOD2(gene name)|psi-mi:TMOD2(display_short)|uniprotkb:NTMOD(gene name synonym)|uniprotkb:Neuronal tropomodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412084|imex:IM-26436-110 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A1L390-1(isoform-parent) ensembl:ENSG00000128872(gene)|ensembl:ENST00000249700(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030426"(growth cone)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051694"(pointed-end actin filament capping)|interpro:IPR004934(Tropomodulin)|interpro:IPR030130|interpro:IPR032675|reactome:R-HSA-390522|refseq:NP_001136357.1|refseq:NP_055363.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+obep09w4klmkB8i13aA5FQW2609606 rogid:km9yOQf3wlXkMxXa/wKFxquWej09606 rigid:7YqljFMCBTaxkOhmzUFuxNzKU0A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A1L390-1 uniprotkb:Q6S8J3 intact:EBI-25412077 intact:EBI-4289913|uniprotkb:Q6S8J4|uniprotkb:Q6S8J8|uniprotkb:Q6S8J5|ensembl:ENSP00000439189|ensembl:ENSP00000507284 psi-mi:a1l3901(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:potee_human(display_long)|uniprotkb:POTEE(gene name)|psi-mi:POTEE(display_short)|uniprotkb:A26C1A(gene name synonym)|uniprotkb:POTE2(gene name synonym)|uniprotkb:ANKRD26-like family C member 1A(gene name synonym)|uniprotkb:Prostate, ovary, testis-expressed protein on chromosome 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412084|imex:IM-26436-110 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A1L390-1(isoform-parent) ensembl:ENSG00000188219(gene)|ensembl:ENST00000356920(transcript)|ensembl:ENST00000683005(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129|reactome:R-HSA-9035034|interpro:IPR020902|refseq:NP_001077007.1|refseq:XP_016859650.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+obep09w4klmkB8i13aA5FQW2609606 rogid:LMuv4bmAG2/uPyH5LR9q+ickvWI9606 rigid:7YqljFMCBTaxkOhmzUFuxNzKU0A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A1L390-1 uniprotkb:O60341 intact:EBI-25412077 intact:EBI-710124|uniprotkb:Q5TH94|uniprotkb:Q5TH95|uniprotkb:Q86VT7|uniprotkb:Q8IXK4|uniprotkb:Q8NDP6|uniprotkb:Q8TAZ3|uniprotkb:Q96AW4|ensembl:ENSP00000349049|uniprotkb:A8MWP9 psi-mi:a1l3901(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:kdm1a_human(display_long)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412084|imex:IM-26436-110 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A1L390-1(isoform-parent) go:"GO:0021987"(cerebral cortex development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|refseq:NP_001009999.1|refseq:NP_055828.2|ensembl:ENSG00000004487(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|ensembl:ENST00000356634(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-34641N|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060992"(response to fungicide)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|interpro:IPR036388|mint:O60341|rcsb pdb:2COM|rcsb pdb:2DW4|rcsb pdb:2EJR|rcsb pdb:2H94|rcsb pdb:2HKO|rcsb pdb:2IW5|rcsb pdb:2L3D|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:2Z3Y|rcsb pdb:2Z5U|rcsb pdb:3ABT|rcsb pdb:3ABU|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4CZZ|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5AFW|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5IT3|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6E1F|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6KGO|rcsb pdb:6KGP|rcsb pdb:6KGQ|rcsb pdb:6KGR|rcsb pdb:6NQM|rcsb pdb:6NQU|rcsb pdb:6NR5|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|rcsb pdb:7E0G|rcsb pdb:7JJL|rcsb pdb:7JJM|rcsb pdb:7JK7|reactome:R-HSA-3214815|reactome:R-HSA-3214842|reactome:R-HSA-5625886|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9679191|reactome:R-HSA-983231 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+obep09w4klmkB8i13aA5FQW2609606 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rigid:7YqljFMCBTaxkOhmzUFuxNzKU0A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A1L390-1 uniprotkb:Q9UQN3 intact:EBI-25412077 intact:EBI-718324|uniprotkb:Q53HC7|uniprotkb:Q9Y4U6|intact:EBI-11161391|uniprotkb:B4DJG8|ensembl:ENSP00000263780 psi-mi:a1l3901(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:chm2b_human(display_long)|uniprotkb:Chromatin-modifying protein 2b(gene name synonym)|uniprotkb:CHMP2.5(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 2-2(gene name synonym)|uniprotkb:CHMP2B(gene name)|psi-mi:CHMP2B(display_short)|uniprotkb:CGI-84(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412084|imex:IM-26436-110 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A1L390-1(isoform-parent) refseq:NP_054762.2|refseq:NP_001231573.1|ensembl:ENSG00000083937(gene)|ensembl:ENST00000263780(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0050890"(cognition)|go:"GO:0061763"(multivesicular body-lysosome fusion)|go:"GO:0061952"(midbody abscission)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|mint:Q9UQN3|rcsb pdb:2JQK|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)|dip:DIP-50766N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+obep09w4klmkB8i13aA5FQW2609606 rogid:WmtZzxKkbkLsgFov/DJDKKGvIto9606 rigid:7YqljFMCBTaxkOhmzUFuxNzKU0A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A1L390-1 uniprotkb:Q96GD4 intact:EBI-25412077 intact:EBI-624291|uniprotkb:O14630|uniprotkb:O60446|uniprotkb:O95083|uniprotkb:Q96DV5|uniprotkb:Q9UQ46|ensembl:ENSP00000463999|uniprotkb:B4DNM4|uniprotkb:D3DTR4|uniprotkb:C7G533|uniprotkb:C7G534|uniprotkb:C7G535|uniprotkb:J9JID1 psi-mi:a1l3901(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:aurkb_human(display_long)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK5(gene name synonym)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412084|imex:IM-26436-110 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:A1L390-1(isoform-parent) go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0043988"(histone H3-S28 phosphorylation)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0009838"(abscission)|go:"GO:0010369"(chromocenter)|go:"GO:0016570"(histone modification)|go:"GO:0019900"(kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0004674"(protein serine/threonine kinase activity)|ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|refseq:NP_001271455.1|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1905116"(positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028772|interpro:IPR030616|mint:Q96GD4|rcsb pdb:4AF3|reactome:R-HSA-141444|reactome:R-HSA-174178|reactome:R-HSA-2467813|reactome:R-HSA-2500257|go:"GO:0051973"(positive regulation of telomerase activity)|reactome:R-HSA-4615885|reactome:R-HSA-5663220|reactome:R-HSA-6804756|reactome:R-HSA-68877|reactome:R-HSA-9022692|reactome:R-HSA-9648025|refseq:NP_004208.2|refseq:NP_001243763.1|refseq:NP_001300879.1|refseq:NP_001300880.1|refseq:NP_001300881.1|refseq:NP_001300882.1|refseq:NP_001300883.1|refseq:NP_001300884.1|refseq:XP_011522372.1|refseq:XP_011522374.1|refseq:XP_016880796.1|dip:DIP-34530N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:+obep09w4klmkB8i13aA5FQW2609606 rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606 rigid:7YqljFMCBTaxkOhmzUFuxNzKU0A false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13009-1 uniprotkb:P56270 intact:EBI-25412191 intact:EBI-1809742|uniprotkb:A8QJL9|uniprotkb:Q15703|uniprotkb:Q99443|uniprotkb:H3BQD6|uniprotkb:G5E927|uniprotkb:Q8NFN7|uniprotkb:C6G496|ensembl:ENSP00000313362 psi-mi:q130091(display_long)|uniprotkb:TIAM1(gene name)|psi-mi:TIAM1(display_short) psi-mi:maz_human(display_long)|uniprotkb:Transcription factor Zif87(gene name synonym)|uniprotkb:Zinc finger protein 801(gene name synonym)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)|uniprotkb:Purine-binding transcription factor(gene name synonym)|uniprotkb:Pur-1(gene name synonym)|uniprotkb:ZF87(gene name synonym)|uniprotkb:ZNF801(gene name synonym)|uniprotkb:Serum amyloid A-activating factor-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412197|imex:IM-26436-244 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13009-1(isoform-parent) refseq:NP_002374.2|refseq:NP_001036004.1|refseq:NP_001263205.1|refseq:NP_001263204.1|ensembl:ENSG00000103495(gene)|ensembl:ENST00000322945(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P56270 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:h0ruHb93yvgrex2b+d2JNrph60A9606 rogid:zuCDXhF2wr8gmTyjBNse9kVUqSw9606 rigid:I8M08KM/ENHS+a9jhpnb1nCA7S4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13009-1 uniprotkb:Q13425 intact:EBI-25412191 intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09 psi-mi:q130091(display_long)|uniprotkb:TIAM1(gene name)|psi-mi:TIAM1(display_short) psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412197|imex:IM-26436-244 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13009-1(isoform-parent) go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:h0ruHb93yvgrex2b+d2JNrph60A9606 rogid:SABgmvArdLH93OpFobs/L3BleVY9606 rigid:I8M08KM/ENHS+a9jhpnb1nCA7S4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13009-1 uniprotkb:Q96QC0 intact:EBI-25412191 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:q130091(display_long)|uniprotkb:TIAM1(gene name)|psi-mi:TIAM1(display_short) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412197|imex:IM-26436-244 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13009-1(isoform-parent) refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:h0ruHb93yvgrex2b+d2JNrph60A9606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:I8M08KM/ENHS+a9jhpnb1nCA7S4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13009-1 uniprotkb:Q6UN15 intact:EBI-25412191 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:q130091(display_long)|uniprotkb:TIAM1(gene name)|psi-mi:TIAM1(display_short) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412197|imex:IM-26436-244 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13009-1(isoform-parent) ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:h0ruHb93yvgrex2b+d2JNrph60A9606 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 rigid:I8M08KM/ENHS+a9jhpnb1nCA7S4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13009-1 uniprotkb:Q9Y4J8 intact:EBI-25412191 intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7 psi-mi:q130091(display_long)|uniprotkb:TIAM1(gene name)|psi-mi:TIAM1(display_short) psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412197|imex:IM-26436-244 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13009-1(isoform-parent) ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:h0ruHb93yvgrex2b+d2JNrph60A9606 rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606 rigid:I8M08KM/ENHS+a9jhpnb1nCA7S4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13009-1 uniprotkb:P11532 intact:EBI-25412191 intact:EBI-295827|uniprotkb:Q9UCW3|uniprotkb:Q9UCW4|uniprotkb:Q02295|uniprotkb:Q14169|uniprotkb:Q14170|uniprotkb:Q5JYU0|uniprotkb:Q7KZ48|intact:EBI-11041646|uniprotkb:A1L0U9|uniprotkb:Q8N754|uniprotkb:E9PDN1|uniprotkb:Q6NSJ9|intact:EBI-12189729|intact:EBI-22423597|intact:EBI-12702600|uniprotkb:E7EQR9|uniprotkb:E7EQS5|uniprotkb:E7ESB2|uniprotkb:E9PDN5|uniprotkb:F5GZY3|uniprotkb:F8VX32|intact:EBI-28985510 psi-mi:q130091(display_long)|uniprotkb:TIAM1(gene name)|psi-mi:TIAM1(display_short) psi-mi:dmd_human(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412197|imex:IM-26436-244 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13009-1(isoform-parent) refseq:NP_000100.2|refseq:NP_003997.1|refseq:NP_004000.1|refseq:NP_004001.1|refseq:NP_004002.2|refseq:NP_004003.1|refseq:NP_004004.1|refseq:NP_004005.1|refseq:NP_004008.1|refseq:NP_004009.1|refseq:NP_004010.1|refseq:NP_004011.2|refseq:NP_004012.1|refseq:NP_004013.1|refseq:NP_004014.1|refseq:NP_004006.1|refseq:NP_004007.1|ensembl:ENST00000682600|ensembl:ENSP00000507640|ensembl:ENST00000361471|ensembl:ENSP00000354464|ensembl:ENSG00000198947|ensembl:ENST00000378680|ensembl:ENSP00000367951|ensembl:ENST00000378702|ensembl:ENSP00000367974|ensembl:ENST00000378723|ensembl:ENSP00000367997|mint:P11532|dip:DIP-32593N|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009986"(cell surface)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|rcsb pdb:1DXX|rcsb pdb:1EG3|rcsb pdb:1EG4|rcsb pdb:3UUN|reactome:R-HSA-3000171|reactome:R-HSA-390522 - - - figure legend:Table S3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:h0ruHb93yvgrex2b+d2JNrph60A9606 rogid:gUFSTsQjsZpAmGI3+6ZPmUebofA9606 rigid:I8M08KM/ENHS+a9jhpnb1nCA7S4 false tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15085-1 uniprotkb:Q96PX9 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-11741362|ensembl:ENSP00000283426 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25399503|imex:IM-26436-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 - - - figure legend:Fig. 4B and G, Extended Data Fig. 4B and 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/20 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rigid:sDaTuE1XYBqRNs78TzfxeHuOhok false flag tag:n-n|sufficient binding region:1-130 yellow fluorescent protein tag:n-n|necessary binding region:1-600 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9NZN5-1 uniprotkb:Q96PX9 intact:EBI-9640168|ensembl:ENSP00000380942 intact:EBI-11741362|ensembl:ENSP00000283426 psi-mi:q9nzn5-1(display_long)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short) psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25400304|imex:IM-26436-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-821440(isoform-parent)|uniprotkb:Q9NZN5-1(isoform-parent)|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 - - - figure legend:Fig. 4B and G, Extended Data Fig. 4B and 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/20 rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rigid:YHq2vNU1eKE36wWVxLzdH8e5GQk false flag tag:n-n|sufficient binding region:1-160 yellow fluorescent protein tag:n-n|necessary binding region:1-600 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75427 uniprotkb:Q96N67 intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689 intact:EBI-2433703|uniprotkb:Q00M63|uniprotkb:Q2PPY7|uniprotkb:Q45RE8|uniprotkb:Q45RE9|uniprotkb:Q5T1B9|uniprotkb:Q5T1C0|uniprotkb:Q6ZV32|uniprotkb:Q8TB82|uniprotkb:Q96NG6|uniprotkb:Q9C092|intact:EBI-7303260|intact:MINT-1683616|uniprotkb:Q96NI0|intact:EBI-28980506|ensembl:ENSP00000489124 psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym) psi-mi:dock7_human(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25400316|imex:IM-26436-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002310.2|refseq:NP_001276863.1|ensembl:ENSG00000077454(gene)|ensembl:ENST00000310300(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0016605"(PML body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 refseq:XP_011540628.1|refseq:NP_001258931.1|refseq:NP_212132.2|ensembl:ENST00000251157|ensembl:ENSP00000251157|ensembl:ENST00000340370|ensembl:ENSP00000340742|ensembl:ENST00000404627|ensembl:ENSP00000384446|ensembl:ENST00000454575|ensembl:ENSP00000413583|ensembl:ENST00000634264|ensembl:ENSP00000489284|ensembl:ENST00000635123|ensembl:ENSP00000489499|ensembl:ENSP00000489124|refseq:NP_001258928.1|refseq:NP_001258929.1|refseq:NP_001258930.1|refseq:NP_001317543.1|ensembl:ENSG00000116641(gene)|ensembl:ENST00000635253(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0045178"(basal part of cell)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|mint:Q96N67|rcsb pdb:6AJ4|rcsb pdb:6AJL|reactome:R-HSA-8875555|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 - - - figure legend:Fig. 6E, 6F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/20 rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606 rogid:PHjIS0j8JJ6Il3knhzjCzMNkxKk9606 rigid:mwBJU0zc/qn2M06z1/r3+ysbGuM false flag tag:n-n mcherry fluorescent protein tag:n-n|sufficient binding region:1678..1678-2114..2114(IPR027357) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5VUJ6 uniprotkb:Q8NF50 intact:EBI-2659666|uniprotkb:Q9P233|uniprotkb:Q9HA88|uniprotkb:F5H2T1|uniprotkb:Q08AD5|ensembl:ENSP00000325091 intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|ensembl:ENSP00000394888|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|intact:EBI-11070681 psi-mi:lrch2_human(display_long)|uniprotkb:KIAA1495(gene name synonym)|uniprotkb:LRCH2(gene name)|psi-mi:LRCH2(display_short) psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25400409|imex:IM-26436-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065922.3|refseq:NP_001230892.1|ensembl:ENSG00000130224(gene)|ensembl:ENST00000317135(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 refseq:XP_011516347.1|refseq:XP_011516349.1|ensembl:ENSG00000107099(gene)|ensembl:ENST00000432829(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061485"(memory T cell proliferation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:XP_011516350.1|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_016870662.1 - - - figure legend:Fig. 6G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/20 rogid:hjJwBxAeVmoDWTtcKK5NzCIDnBo9606 rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606 rigid:2w4gervJWlpUvEOANMCw+Ms7Yss false flag tag:n-n|necessary binding region:1..1-642..642 yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96PX9 uniprotkb:O15085-1 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-25399484|ensembl:ENSP00000354644 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25400452|imex:IM-26436-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) - - - figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/20 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rigid:Pckpt6wqPKIq311n83MWkmp8h5I false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96PX9 uniprotkb:Q14344 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-465387|ensembl:ENSP00000400717|uniprotkb:Q8TD70|uniprotkb:B7Z7R0|uniprotkb:F5H1G8|uniprotkb:B2R977 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:gna13_human(display_long)|uniprotkb:GNA13(gene name)|psi-mi:GNA13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25400452|imex:IM-26436-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 ensembl:ENSG00000120063(gene)|ensembl:ENST00000439174(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-428930|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-456926|refseq:NP_006563.2|refseq:NP_001269354.1 - - - figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/20 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:ZYmlpIogjya3/ejteQS1YC+LqKI9606 rigid:Pckpt6wqPKIq311n83MWkmp8h5I false yellow fluorescent protein tag:n-n flag tag:n-n|mutation causing an interaction:226-226 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96PX9 uniprotkb:Q9NZN5-1 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-9640168|ensembl:ENSP00000380942 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:q9nzn5-1(display_long)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25400593|imex:IM-26436-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 intact:EBI-821440(isoform-parent)|uniprotkb:Q9NZN5-1(isoform-parent)|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript) - - - figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/20 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606 rigid:dpV2MBaoCWvUoH1tCmvdJ/3AmLQ false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96PX9 uniprotkb:Q14344 intact:EBI-11741362|ensembl:ENSP00000283426 intact:EBI-465387|ensembl:ENSP00000400717|uniprotkb:Q8TD70|uniprotkb:B7Z7R0|uniprotkb:F5H1G8|uniprotkb:B2R977 psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:gna13_human(display_long)|uniprotkb:GNA13(gene name)|psi-mi:GNA13(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25400593|imex:IM-26436-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 ensembl:ENSG00000120063(gene)|ensembl:ENST00000439174(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-428930|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-456926|refseq:NP_006563.2|refseq:NP_001269354.1 - - - figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/20 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rogid:ZYmlpIogjya3/ejteQS1YC+LqKI9606 rigid:dpV2MBaoCWvUoH1tCmvdJ/3AmLQ false yellow fluorescent protein tag:n-n flag tag:n-n|mutation causing an interaction:226-226 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O43307-1 uniprotkb:Q8N1W1-6 intact:EBI-25399711|ensembl:ENSP00000253401|ensembl:ENSP00000500829 intact:EBI-25399694|ensembl:ENSP00000411459|ensembl:ENSP00000441913 psi-mi:o43307-1(display_long)|uniprotkb:Collybistin(gene name synonym)|uniprotkb:PEM-2 homolog(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 9(gene name synonym)|uniprotkb:"CB3(SH3+)"(isoform synonym)|uniprotkb:ARHGEF9(gene name)|psi-mi:ARHGEF9(display_short)|uniprotkb:ARHDH9(gene name synonym)|uniprotkb:KIAA0424(gene name synonym) psi-mi:q8n1w1-6(display_long)|uniprotkb:ARHGEF28(gene name)|psi-mi:ARHGEF28(display_short)|uniprotkb:KIAA1998(gene name synonym)|uniprotkb:RGNEF(gene name synonym)|uniprotkb:190 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Rho guanine nucleotide exchange factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412317|imex:IM-26436-290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131089(gene)|ensembl:ENST00000253401(transcript)|ensembl:ENST00000671907(transcript)|intact:EBI-3447299(isoform-parent) intact:EBI-9050764(isoform-parent)|ensembl:ENSG00000214944(gene)|ensembl:ENST00000437974(transcript)|ensembl:ENST00000545377(transcript) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:fNeHhwbyPWGv+2Iak2k7AE/gDd49606 rogid:E6MBNGfnhdyjJIpeFCWaFuVXsq89606 rigid:vCbrlYK+7R7I4Q/nhzwDJbLpBNA false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P11274-1 uniprotkb:Q8N4T4-1 intact:EBI-8658094|ensembl:ENSP00000303507|intact:MINT-5222317 intact:EBI-25408274 psi-mi:p11274-1(display_long)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym) psi-mi:q8n4t41(display_long)|uniprotkb:ARHGEF39(gene name)|psi-mi:ARHGEF39(display_short)|uniprotkb:C9orf100(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412217|imex:IM-26436-246 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|intact:EBI-712838(isoform-parent)|uniprotkb:P11274-1(isoform-parent) uniprotkb:Q8N4T4-1(isoform-parent) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606 rogid:wrZFZm3TbFo81Mew1obI2PelMQc9606 rigid:WZ9qvrarLQ4oqZtmfSqozwzc9f8 false flag tag:n-n yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7Z5H3-2 uniprotkb:Q5JSP0 intact:EBI-12084490|ensembl:ENSP00000412461 intact:EBI-4403141|uniprotkb:Q4VX84|uniprotkb:Q7Z7D9|uniprotkb:Q8N5G1|uniprotkb:F8W7P2|ensembl:ENSP00000336914|ensembl:ENSP00000364631|ensembl:ENSP00000496819 psi-mi:q7z5h3-2(display_long)|uniprotkb:ARHGAP22(gene name)|psi-mi:ARHGAP22(display_short)|uniprotkb:RHOGAP2(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 22(gene name synonym) psi-mi:fgd3_human(display_long)|uniprotkb:FGD3(gene name)|psi-mi:FGD3(display_short)|uniprotkb:ZFYVE5(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412227|imex:IM-26436-88 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-3866859(isoform-parent)|ensembl:ENSG00000128805(gene)|ensembl:ENST00000417912(transcript)|uniprotkb:Q7Z5H3-2(isoform-parent) refseq:NP_001077005.1|refseq:NP_149077.2|refseq:NP_001273922.1|refseq:XP_016870763.1|ensembl:ENSG00000127084(gene)|ensembl:ENST00000337352(transcript)|ensembl:ENST00000375482(transcript)|ensembl:ENST00000468206(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|rcsb pdb:2COC|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 - isoform-comment:No experimental confirmation available. - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:lxGuKxp6+lG5FC1GqNPW9YX9X509606 rogid:GPfnTNLHRBnUKhWFeaYG7Z6U5xA9606 rigid:SWNSmNF9Nw1eccI/TN59ArSUKcY false flag tag:n-n yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O15085-1 uniprotkb:Q8TER5-1 intact:EBI-25399484|ensembl:ENSP00000354644 intact:EBI-25399492|ensembl:ENSP00000298694 psi-mi:o15085-1(display_long)|uniprotkb:PDZ-RhoGEF(gene name synonym)|uniprotkb:KIAA0380(gene name synonym)|uniprotkb:ARHGEF11(gene name)|psi-mi:ARHGEF11(display_short) psi-mi:q8ter5-1(display_long)|uniprotkb:Protein SOLO(gene name synonym)|uniprotkb:ARHGEF40(gene name)|psi-mi:ARHGEF40(display_short)|uniprotkb:SOLO(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412237|imex:IM-26436-286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132694(gene)|ensembl:ENST00000361409(transcript)|intact:EBI-311099(isoform-parent) ensembl:ENSG00000165801(gene)|ensembl:ENST00000298694(transcript)|intact:EBI-715355(isoform-parent) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:1xhgHWC/U14RFSWNJmZudD2/DdQ9606 rogid:fhQZOvovcDb+ONc6C3xrzICOfKo9606 rigid:D5suV8zsHepnkEpIoj8nccv2DaI false flag tag:n-n yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8K0Q5 uniprotkb:Q96PX9 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-11741362|ensembl:ENSP00000283426 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:pkh4b_human(display_long)|uniprotkb:PLEKHG4B(gene name)|psi-mi:PLEKHG4B(display_short)|uniprotkb:KIAA1909(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412247|imex:IM-26436-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_443141.3|ensembl:ENSG00000153404(gene)|ensembl:ENST00000283426(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|reactome:R-HSA-9013148 - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:hD9xbPc70VzfZz8UZKPjciUNM0w9606 rigid:hg6k8weABrKiNPI7kssoD4GlQiY false flag tag:n-n yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8K0Q5 uniprotkb:Q7Z6J4 intact:EBI-8586076|ensembl:ENSMUSP00000044834|uniprotkb:Q8R196|uniprotkb:Q8BP03|intact:UNK-5519903 intact:EBI-1057190|uniprotkb:Q5T8I1|uniprotkb:Q6P6A8|uniprotkb:Q6ZNL5|uniprotkb:Q8IZ32|uniprotkb:Q8N868|uniprotkb:Q9H7M2|ensembl:ENSP00000274963 psi-mi:rhg18_mouse(display_long)|uniprotkb:Arhgap18(gene name)|psi-mi:Arhgap18(display_short)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym) psi-mi:fgd2_human(display_long)|uniprotkb:FGD2(gene name)|psi-mi:FGD2(display_short)|uniprotkb:ZFYVE4(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412257|imex:IM-26436-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000039557(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|ensembl:ENSMUSG00000039031(gene)|refseq:NP_789807.1 refseq:NP_775829.2|ensembl:ENSG00000146192(gene)|ensembl:ENST00000274963(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046847"(filopodium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035899|interpro:IPR035941|interpro:IPR037797|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148 - comment:mint|function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:6kWRMCu4bV3EfpKLvYZVkOcQveY10090 rogid:jAx/1RNr9M1EoPP9w6wks8dRLaA9606 rigid:NnFjCRn1J6vchR8CBbHCKaUoQhg false flag tag:n-n yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q923Q2 uniprotkb:Q96QB1 intact:EBI-8393503|intact:MINT-4135694|uniprotkb:Q8K369|uniprotkb:E9PUB5|ensembl:ENSMUSP00000106109 intact:EBI-2608428|uniprotkb:B4DR10|uniprotkb:E9PGY9|uniprotkb:O14868|uniprotkb:O43199|uniprotkb:Q7Z5R8|uniprotkb:Q9C0E0|uniprotkb:Q9H7A2|ensembl:ENSP00000276297|uniprotkb:B8PTI0|uniprotkb:E9PDZ8|uniprotkb:E9PF76|uniprotkb:Q86UC6 psi-mi:sta13_mouse(display_long)|uniprotkb:Stard13(gene name)|psi-mi:Stard13(display_short)|uniprotkb:START domain-containing protein 13(gene name synonym) psi-mi:rhg07_human(display_long)|uniprotkb:DLC1(gene name)|psi-mi:DLC1(display_short)|uniprotkb:ARHGAP7(gene name synonym)|uniprotkb:KIAA1723(gene name synonym)|uniprotkb:STARD12(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 7(gene name synonym)|uniprotkb:Deleted in liver cancer 1 protein(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 12(gene name synonym)|uniprotkb:START domain-containing protein 12(gene name synonym)|uniprotkb:HP protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412267|imex:IM-26436-112 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_666370.3|ensembl:ENSMUSG00000016128(gene)|ensembl:ENSMUST00000110483(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|mint:Q923Q2|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013148|reactome:R-MMU-9013106 refseq:NP_079043.3|refseq:NP_001157743.1|refseq:NP_006085.2|refseq:NP_872584.2|refseq:XP_005273431.1|refseq:NP_001303597.1|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|interpro:IPR028854|mint:Q96QB1|rcsb pdb:2DKY|rcsb pdb:2GYT|rcsb pdb:2KAP|rcsb pdb:2LOZ|rcsb pdb:3KUQ|rcsb pdb:5FZT|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|refseq:NP_001335013.1|refseq:NP_001335010.1|refseq:NP_001335011.1|refseq:NP_001335012.1|ensembl:ENSG00000164741(gene)|ensembl:ENST00000276297(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008289"(lipid binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0021575"(hindbrain morphogenesis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030900"(forebrain development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|dip:DIP-56928N - comment:mint|function:May function as a GTPase-activating protein - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:RC3mRuTIcK/fA9HFo8+NcYVDt5M10090 rogid:ZTy7Vk68AF6g9TSChz7j8Qxzs7c9606 rigid:fpbjdbntbVGSs3rqdz8jZDxk96M false flag tag:n-n yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15052-1 uniprotkb:Q14155-4 intact:EBI-25409944|ensembl:ENSP00000250617 intact:EBI-25410853|ensembl:ENSP00000364893 psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:q14155-4(display_long)|uniprotkb:Beta-Pix(gene name synonym)|uniprotkb:COOL-1(gene name synonym)|uniprotkb:PAK-interacting exchange factor beta(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:Nbla10314(orf name)|uniprotkb:ARHGEF7(gene name)|psi-mi:ARHGEF7(display_short)|uniprotkb:COOL1(gene name synonym)|uniprotkb:KIAA0142(gene name synonym)|uniprotkb:P85SPR(gene name synonym)|uniprotkb:PAK3BP(gene name synonym)|uniprotkb:PIXB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412327|imex:IM-26436-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) ensembl:ENSG00000102606(gene)|ensembl:ENST00000375741(transcript)|intact:EBI-717515(isoform-parent) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/27 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rogid:0I59YglGXcYP7fFKIAWM6uCZY8Q9606 rigid:98iiF6nSof/vlpgnXbnKtBPmcck false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96N67-2 uniprotkb:Q640N3-2 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-25409036 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:q640n32(display_long)|uniprotkb:Arhgap30(gene name)|psi-mi:Arhgap30(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412407|imex:IM-26436-208 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) uniprotkb:Q640N3-2(isoform-parent) - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:yXn0Kqt6VVngufgXYc7Qp0Us8R410090 rigid:SXkUzWVjS/Nf3NnhzqU4T++l2J8 false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H7D0-1 uniprotkb:Q14185 intact:EBI-25409131 intact:EBI-446740|uniprotkb:A9Z1Z5|ensembl:ENSP00000280333 psi-mi:q9h7d01(display_long)|uniprotkb:DOCK5(gene name)|psi-mi:DOCK5(display_short) psi-mi:dock1_human(display_long)|uniprotkb:180 kDa protein downstream of CRK(gene name synonym)|uniprotkb:DOCK1(gene name)|psi-mi:DOCK1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412397|imex:IM-26436-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q9H7D0-1(isoform-parent) ensembl:ENSP00000280333|dip:DIP-29391N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035892|interpro:IPR036028|interpro:IPR042455|interpro:IPR043161|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000150760(gene)|ensembl:ENST00000280333(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|mint:Q14185|rcsb pdb:3L4C|reactome:R-HSA-2029482|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9664422|reactome:R-HSA-983231|interpro:IPR043162|refseq:NP_001371.1 - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:/+sUfMB7hLZjdyhsMQ8WKJoXXLU9606 rogid:SsN4jN+OIbDOnPEthCF7ZdEJrdc9606 rigid:ZMseYf+A4b5jFW0//n/LXyllizM false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N1I0-3 uniprotkb:Q92888-2 intact:EBI-21557617 intact:EBI-21604343 psi-mi:q8n1i03(display_long)|uniprotkb:DOCK4(gene name)|psi-mi:DOCK4(display_short)|uniprotkb:KIAA0716(gene name synonym) psi-mi:q928882(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412387|imex:IM-26436-192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8N1I0-3(isoform-parent) uniprotkb:Q92888-2(isoform-parent) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gGBcAqhJmoeDDtSXxJQEqqJM2D49606 rogid:Flf39qLhNvNdGxTHQo58+ESBnCg9606 rigid:C/kx0+CYWwMPpzynZREG8WjOkvI false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A7KAX9-1 uniprotkb:Q8N264-1 intact:EBI-25408873|ensembl:ENSP00000310561 intact:EBI-15944596|ensembl:ENSP00000378611 psi-mi:a7kax9-1(display_long)|uniprotkb:Brain-specific Rho GTPase-activating protein(gene name synonym)|uniprotkb:GAB-associated Cdc42/Rac GTPase-activating protein(gene name synonym)|uniprotkb:GC-GAP(gene name synonym)|uniprotkb:GTPase regulator interacting with TrkA(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 32(gene name synonym)|uniprotkb:Rho/Cdc42/Rac GTPase-activating protein RICS(gene name synonym)|uniprotkb:RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling(gene name synonym)|uniprotkb:p200RhoGAP(gene name synonym)|uniprotkb:p250GAP(gene name synonym)|uniprotkb:PX-RICS(isoform synonym)|uniprotkb:ARHGAP32(gene name)|psi-mi:ARHGAP32(display_short)|uniprotkb:GRIT(gene name synonym)|uniprotkb:KIAA0712(gene name synonym)|uniprotkb:RICS(gene name synonym) psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412377|imex:IM-26436-252 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000134909(gene)|ensembl:ENST00000310343(transcript)|uniprotkb:A7KAX9-1(isoform-parent)|intact:EBI-308663(isoform-parent) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:V51KfHcAYYMGvIsWaG5hNqZ49Yk9606 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rigid:27UntQ5bDF6T9GntUQEZiYI40gs false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O54997 uniprotkb:Q01968-2 intact:EBI-25412357 intact:EBI-11749425|ensembl:ENSP00000349635 psi-mi:o54997_mouse(display_long)|uniprotkb:Inpp5b(gene name)|psi-mi:Inpp5b(display_short)|uniprotkb:INPP5P(gene name synonym) psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412367|imex:IM-26436-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016791"(phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|interpro:IPR036691|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR000300(Inositol polyphosphate related phosphatase) intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:y4UTcXCOw6ZUQj/tXSv0MWYS5rs10090 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rigid:QJdgEoJ3fAYzR3+REPV6b+L/BuQ false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13017-1 uniprotkb:Q8IZD9 intact:EBI-25409992 intact:EBI-1752361|uniprotkb:O15017|ensembl:ENSP00000266037 psi-mi:q130171(display_long)|uniprotkb:ARHGAP5(gene name)|psi-mi:ARHGAP5(display_short)|uniprotkb:RHOGAP5(gene name synonym) psi-mi:dock3_human(display_long)|uniprotkb:DOCK3(gene name)|psi-mi:DOCK3(display_short)|uniprotkb:KIAA0299(gene name synonym)|uniprotkb:MOCA(gene name synonym)|uniprotkb:Modifier of cell adhesion(gene name synonym)|uniprotkb:Presenilin-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412347|imex:IM-26436-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q13017-1(isoform-parent) ensembl:ENSP00000266037|refseq:NP_004938.1|ensembl:ENSG00000088538(gene)|ensembl:ENST00000266037(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026791|interpro:IPR026800|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035767|interpro:IPR035892|interpro:IPR036028|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9032759|reactome:R-HSA-983231 - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:CcK8+6n27QR+L45eRsmnJP82TQE9606 rogid:iOab1J+w2HOMYtMCju+iysQ6oT09606 rigid:XzzTulRBzovvMNsXqGiPS+A4wM8 false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96D37 uniprotkb:O94887-1 intact:EBI-7875353|intact:MINT-1492278|ensembl:ENSP00000472803 intact:EBI-25408805 psi-mi:q96d37_human(display_long)|uniprotkb:VAV1(gene name)|psi-mi:VAV1(display_short) psi-mi:o948871(display_long)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:PLEKHC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412337|imex:IM-26436-250 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245136.1|refseq:NP_005419.2|refseq:NP_001245135.1|ensembl:ENSG00000141968(gene)|ensembl:ENST00000599806(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0046872"(metal ion binding)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000980(SH2 motif)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR028530|interpro:IPR035729|interpro:IPR035730|interpro:IPR035879|interpro:IPR035899|interpro:IPR036028|interpro:IPR036860|interpro:IPR036872|interpro:IPR037832|mint:Q96D37 uniprotkb:O94887-1(isoform-parent) - comment:mint - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:I9BRr/7Hp31ABMQcpJzpW311RLc9606 rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606 rigid:0FN4wG6BG9FLNxS586tRlIPbU7c false flag tag:n-n yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6ZSZ5-2 uniprotkb:Q8N1W1-6 intact:EBI-21581135 intact:EBI-25399694|ensembl:ENSP00000411459|ensembl:ENSP00000441913 psi-mi:q6zsz52(display_long)|uniprotkb:ARHGEF18(gene name)|psi-mi:ARHGEF18(display_short)|uniprotkb:KIAA0521(gene name synonym)|uniprotkb:p114(isoform synonym) psi-mi:q8n1w1-6(display_long)|uniprotkb:ARHGEF28(gene name)|psi-mi:ARHGEF28(display_short)|uniprotkb:KIAA1998(gene name synonym)|uniprotkb:RGNEF(gene name synonym)|uniprotkb:190 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Rho guanine nucleotide exchange factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412307|imex:IM-26436-288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q6ZSZ5-2(isoform-parent) intact:EBI-9050764(isoform-parent)|ensembl:ENSG00000214944(gene)|ensembl:ENST00000437974(transcript)|ensembl:ENST00000545377(transcript) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:8bV6ZFH3sgT7nzJ8AVgWbcdjTvg9606 rogid:E6MBNGfnhdyjJIpeFCWaFuVXsq89606 rigid:ZFSOPVcXZk8OXpGZOdASki7SPT4 false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O43295-2 uniprotkb:Q8N264-1 intact:EBI-11063100|ensembl:ENSP00000353587 intact:EBI-15944596|ensembl:ENSP00000378611 psi-mi:o43295-2(display_long)|uniprotkb:SRGAP3(gene name)|psi-mi:SRGAP3(display_short)|uniprotkb:ARHGAP14(gene name synonym)|uniprotkb:KIAA0411(gene name synonym)|uniprotkb:KIAA1156(gene name synonym)|uniprotkb:MEGAP(gene name synonym)|uniprotkb:Mental disorder-associated GAP(gene name synonym)|uniprotkb:Rho GTPase-activating protein 14(gene name synonym)|uniprotkb:SRGAP2(gene name synonym)|uniprotkb:WAVE-associated Rac GTPase-activating protein(gene name synonym)|uniprotkb:MEGAPb(isoform synonym)|uniprotkb:srGAP3b(isoform synonym) psi-mi:q8n264-1(display_long)|uniprotkb:ARHGAP24(gene name)|psi-mi:ARHGAP24(display_short)|uniprotkb:FILGAP(gene name synonym)|uniprotkb:Filamin-A-associated RhoGAP(gene name synonym)|uniprotkb:RAC1- and CDC42-specific GTPase-activating protein of 72 kDa(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 24(gene name synonym)|uniprotkb:RhoGAP of 73 kDa(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-88(gene name synonym)|uniprotkb:p73RhoGAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412297|imex:IM-26436-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196220(gene)|ensembl:ENST00000360413(transcript)|intact:EBI-368166(isoform-parent)|uniprotkb:O43295-2(isoform-parent) ensembl:ENSG00000138639(gene)|ensembl:ENST00000395184(transcript)|intact:EBI-988764(isoform-parent)|uniprotkb:Q8N264-1(isoform-parent) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:EatjevYRtQ8UAObKRXgUkKHN3jY9606 rogid:l46EiTbxT2jF9tlQv+DM9Jb2d5k9606 rigid:jSmnplAGakaHYIWLkASU8P9RLNk false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7Z6B7-1 uniprotkb:Q91Z67 intact:EBI-25399647|ensembl:ENSP00000347198 intact:EBI-16730393|ensembl:ENSMUSP00000095195|uniprotkb:B2RY13|uniprotkb:Q3V1V8|uniprotkb:Q61054 psi-mi:q7z6b7-1(display_long)|uniprotkb:Rho GTPase-activating protein 13(gene name synonym)|uniprotkb:SRGAP1(gene name)|psi-mi:SRGAP1(display_short)|uniprotkb:ARHGAP13(gene name synonym)|uniprotkb:KIAA1304(gene name synonym) psi-mi:srgp2_mouse(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:Formin-binding protein 27(gene name synonym)|uniprotkb:Srgap2(gene name)|psi-mi:Srgap2(display_short)|uniprotkb:Fbp27(gene name synonym)|uniprotkb:Fnbp2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412287|imex:IM-26436-90 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196935(gene)|ensembl:ENST00000355086(transcript)|intact:EBI-2481729(isoform-parent) ensembl:ENSMUSG00000026425(gene)|ensembl:ENSMUST00000097588(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:Q91Z67|reactome:R-MMU-5663220|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|refseq:NP_001074480.2|refseq:XP_006529197.1 - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:90QBhF8JA+PU6aRd6e4WwQ/FSvg9606 rogid:MLCAa8wEQvKNPatehgSzcizs2YI10090 rigid:p3voTbhj1WT+53+hu+hkhOzGdtw false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BN58-3 uniprotkb:Q6ZW31-1 intact:EBI-25408701 intact:EBI-25399601|ensembl:ENSP00000341489 psi-mi:q8bn583(display_long)|uniprotkb:Arhgap28(gene name)|psi-mi:Arhgap28(display_short)|uniprotkb:Kiaa1314(gene name synonym) psi-mi:q6zw31-1(display_long)|uniprotkb:Synapse defective protein 1 homolog 1(gene name synonym)|uniprotkb:SYDE1(gene name)|psi-mi:SYDE1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412277|imex:IM-26436-248 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q8BN58-3(isoform-parent) intact:EBI-11603303(isoform-parent)|ensembl:ENSG00000105137(gene)|ensembl:ENST00000342784(transcript) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:Y6++JdU1pZjBm59V2SIyoJojh9w10090 rogid:+ws2oC7zk50NiisvGoYVDz7ofyE9606 rigid:iybnWuCYnnoJBKRzNKCzT5e3cUk false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96HP0 uniprotkb:O75427 intact:EBI-4401295|uniprotkb:A6H8X5|uniprotkb:Q7Z7P4|uniprotkb:Q9P2F2|intact:EBI-28986399|ensembl:ENSP00000294618 intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689 psi-mi:dock6_human(display_long)|uniprotkb:DOCK6(gene name)|psi-mi:DOCK6(display_short)|uniprotkb:KIAA1395(gene name synonym) psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412462|imex:IM-26436-212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065863.2|ensembl:ENSP00000294618|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000130158(gene)|ensembl:ENST00000294618(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-983231 refseq:NP_002310.2|refseq:NP_001276863.1|ensembl:ENSG00000077454(gene)|ensembl:ENST00000310300(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0016605"(PML body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:3I/PTxZBJythUz5yzxfTIhhj5io9606 rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606 rigid:53/2Wi/13+p43PX3Pe7tIueVku4 false mcherry fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96N67-2 uniprotkb:Q96II8 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412452|imex:IM-26436-210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606 rigid:Ne1I1tLmHKebZgLuEJ/ZCa4Ka3w false mcherry fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q17R89-1 uniprotkb:Q68EM7-2 intact:EBI-25410514|ensembl:ENSP00000368994 intact:EBI-3957963|ensembl:ENSP00000303130|ensembl:ENSP00000500849 psi-mi:q17r89-1(display_long)|uniprotkb:NPC-A-10(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)|uniprotkb:ARHGAP44(gene name)|psi-mi:ARHGAP44(display_short)|uniprotkb:KIAA0672(gene name synonym)|uniprotkb:RICH2(gene name synonym) psi-mi:q68em7-2(display_long)|uniprotkb:ARHGAP17(gene name)|psi-mi:ARHGAP17(display_short)|uniprotkb:RICH1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 17(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 1(gene name synonym)|uniprotkb:MSTP066(orf name)|uniprotkb:MSTP110(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412422|imex:IM-26436-92 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000006740(gene)|ensembl:ENST00000379672(transcript)|intact:EBI-720416(isoform-parent) intact:EBI-1642807(isoform-parent)|uniprotkb:Q68EM7-2(isoform-parent)|ensembl:ENSG00000140750(gene)|ensembl:ENSG00000288353(gene)|ensembl:ENST00000303665(transcript)|ensembl:ENST00000673196(transcript) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:gN2xiWHjD8x8sIV6o2YJV+/RRSQ9606 rogid:nC1rvE2a2rdv25O/dZfIjEenKEA9606 rigid:q4SuYVuKR4CjxXcdSLJZSyp5/wo false yellow fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96N67-2 uniprotkb:Q9Y2L9 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-2797324|uniprotkb:Q7Z5F7|uniprotkb:Q7Z5F6|uniprotkb:Q5TBU9|uniprotkb:Q2KHR1|uniprotkb:B7ZLL5|uniprotkb:F8W6F0|uniprotkb:Q17R43|ensembl:ENSP00000374448 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:lrch1_human(display_long)|uniprotkb:CHDC1(gene name synonym)|uniprotkb:KIAA1016(gene name synonym)|uniprotkb:Calponin homology domain-containing protein 1(gene name synonym)|uniprotkb:Neuronal protein 81(gene name synonym)|uniprotkb:LRCH1(gene name)|psi-mi:LRCH1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412432|imex:IM-26436-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:NP_001157685.1|refseq:NP_055931.1|refseq:NP_001157683.1|ensembl:ENSG00000136141(gene)|ensembl:ENST00000389798(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:3oNqV4dI/4ZHz1sUSsc8nmg0j049606 rigid:tsgChp5tTBLQsSjyrtXsltE23DI false mcherry fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96N67-2 uniprotkb:Q5VUJ6 intact:EBI-11045275|ensembl:ENSP00000413583 intact:EBI-2659666|uniprotkb:Q9P233|uniprotkb:Q9HA88|uniprotkb:F5H2T1|uniprotkb:Q08AD5|ensembl:ENSP00000325091 psi-mi:q96n67-2(display_long)|uniprotkb:DOCK7(gene name)|psi-mi:DOCK7(display_short)|uniprotkb:KIAA1771(gene name synonym) psi-mi:lrch2_human(display_long)|uniprotkb:KIAA1495(gene name synonym)|uniprotkb:LRCH2(gene name)|psi-mi:LRCH2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412442|imex:IM-26436-292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2433703(isoform-parent)|uniprotkb:Q96N67-2(isoform-parent)|ensembl:ENSG00000116641(gene)|ensembl:ENST00000454575(transcript) refseq:NP_065922.3|refseq:NP_001230892.1|ensembl:ENSG00000130224(gene)|ensembl:ENST00000317135(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - isoform-comment:Contains a phosphoserine at position 1429. Contains a phosphoserine at position 1421. Contains a phosphoserine at position 1425. - figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:qBljovoyHShcD3CHzZyIZKUOLzg9606 rogid:hjJwBxAeVmoDWTtcKK5NzCIDnBo9606 rigid:+vXKfSeQI3QcSH4a5aOWOTE5ZAA false mcherry fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NF50-3 uniprotkb:O75427 intact:EBI-25409271|ensembl:ENSP00000408464 intact:EBI-718707|uniprotkb:Q8WV85|uniprotkb:Q96ID0|uniprotkb:A4D2D5|ensembl:ENSP00000309689 psi-mi:q8nf50-3(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:lrch4_human(display_long)|uniprotkb:Leucine-rich repeat neuronal protein 4(gene name synonym)|uniprotkb:LRCH4(gene name)|psi-mi:LRCH4(display_short)|uniprotkb:LRN(gene name synonym)|uniprotkb:LRRN4(gene name synonym)|uniprotkb:LRRN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412472|imex:IM-26436-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000107099(gene)|ensembl:ENST00000453981(transcript)|intact:EBI-2548605(isoform-parent) refseq:NP_002310.2|refseq:NP_001276863.1|ensembl:ENSG00000077454(gene)|ensembl:ENST00000310300(transcript)|go:"GO:0007399"(nervous system development)|go:"GO:0016605"(PML body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/30 rogid:nEcgxLOhqIvr64/yspla/Ta00To9606 rogid:oE4ILE6y/yYV10+MFT0PRwUXotg9606 rigid:7Y9B+CT4MIcQy7S9MsbXXiDG2pE false mcherry fluorescent protein tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q17R89-1 uniprotkb:Q15052-1 intact:EBI-25410514|ensembl:ENSP00000368994 intact:EBI-25409944|ensembl:ENSP00000250617 psi-mi:q17r89-1(display_long)|uniprotkb:NPC-A-10(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein RICH2(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 2(gene name synonym)|uniprotkb:ARHGAP44(gene name)|psi-mi:ARHGAP44(display_short)|uniprotkb:KIAA0672(gene name synonym)|uniprotkb:RICH2(gene name synonym) psi-mi:q15052-1(display_long)|uniprotkb:Alpha-Pix(gene name synonym)|uniprotkb:COOL-2(gene name synonym)|uniprotkb:PAK-interacting exchange factor alpha(gene name synonym)|uniprotkb:Rac/Cdc42 guanine nucleotide exchange factor 6(gene name synonym)|uniprotkb:ARHGEF6(gene name)|psi-mi:ARHGEF6(display_short)|uniprotkb:COOL2(gene name synonym)|uniprotkb:KIAA0006(gene name synonym)|uniprotkb:PIXA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Muller et al. (2020) pubmed:32203420|imex:IM-26436 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25412735|imex:IM-26436-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000006740(gene)|ensembl:ENST00000379672(transcript)|intact:EBI-720416(isoform-parent) intact:EBI-1642523(isoform-parent)|ensembl:ENSG00000129675(gene)|ensembl:ENST00000250617(transcript) - - - figure legend:Extended Data Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/01/15 2020/01/27 rogid:gN2xiWHjD8x8sIV6o2YJV+/RRSQ9606 rogid:i0wD4z4cHFbao49tTRqN2m9Qw7w9606 rigid:lxLrwEEx7pLh3+WUq8QV26IzQFo false flag tag:n-n yellow fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)