#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6ZNK6 uniprotkb:Q6DD88 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:O95831 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q5T447 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2691157|uniprotkb:B3KPV7|uniprotkb:B3KRH4|uniprotkb:Q5T448|uniprotkb:Q9H783|ensembl:ENSP00000361245 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:hecd3_human(display_long)|uniprotkb:HECT domain-containing protein 3(gene name synonym)|uniprotkb:HECTD3(gene name)|psi-mi:HECTD3(display_short)|uniprotkb:HECT-type E3 ubiquitin transferase HECTD3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_078878.3|ensembl:ENSG00000126107(gene)|ensembl:ENST00000372172(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000569(HECT)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR035983|interpro:IPR042469|mint:Q5T447|reactome:R-HSA-983168|go:"GO:0019905"(syntaxin binding) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:laodrF8CReKmM4d6n3sHGBmQB6Q9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P35613 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9NYU2 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1056389|uniprotkb:Q53SL3|uniprotkb:Q8IW30|uniprotkb:Q9H8I4|uniprotkb:Q53QP2|ensembl:ENSP00000259253 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:uggg1_human(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UGCGL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_064505.1|ensembl:ENSG00000136731(gene)|ensembl:ENST00000259253(transcript)|go:"GO:0003980"("UDP-glucose:glycoprotein glucosyltransferase activity")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051084"('de novo' posttranslational protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|interpro:IPR009448("UDP-glucose:Glycoprotein Glucosyltransferase")|interpro:IPR029044|interpro:IPR040497|interpro:IPR040525|interpro:IPR040692|interpro:IPR040693|interpro:IPR040694|mint:Q9NYU2|reactome:R-HSA-901032 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:WgjCB9PJiHtQXloeFEerSmIoQU89606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P08240 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-726981|ensembl:ENSP00000328023|uniprotkb:Q9BVJ4|uniprotkb:A6NIB3|uniprotkb:B2R5Z8|uniprotkb:B4E0H3|uniprotkb:E9PJS4 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:srpra_human(display_long)|uniprotkb:SRPRA(gene name)|psi-mi:SRPRA(display_short)|uniprotkb:Docking protein alpha(gene name synonym)|uniprotkb:SRPR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 rcsb pdb:2FH5|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|rcsb pdb:2GO5|go:"GO:0045047"(protein targeting to ER)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|rcsb pdb:5L3Q|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007222(Signal recognition particle receptor, alpha subunit, N-terminal)|interpro:IPR011012(Longin-like)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101|mint:P08240|rcsb pdb:6Y32|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|ensembl:ENSG00000182934(gene)|ensembl:ENST00000332118(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|refseq:NP_001171313.1|refseq:NP_003130.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:4ag/lxPfDGSDWhpnuwQynTvCpuU9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y285 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_004452.1|ensembl:ENSG00000179115(gene)|ensembl:ENST00000314606(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|dip:DIP-53610N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y3I0 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:O15294 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q92769 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P05023 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P13796 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-698036|uniprotkb:Q5TBN4|uniprotkb:B2R613|uniprotkb:B4DUA0|ensembl:ENSP00000315757|ensembl:ENSP00000381581 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:plsl_human(display_long)|uniprotkb:L-plastin(gene name synonym)|uniprotkb:Lymphocyte cytosolic protein 1(gene name synonym)|uniprotkb:LC64P(gene name synonym)|uniprotkb:LCP1(gene name)|psi-mi:LCP1(display_short)|uniprotkb:PLS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_002289.2|refseq:XP_005266431.1|dip:DIP-34767N|ensembl:ENSG00000136167(gene)|ensembl:ENST00000323076(transcript)|ensembl:ENST00000398576(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002102"(podosome)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|rcsb pdb:2D85|rcsb pdb:5JOJ|rcsb pdb:5JOL|reactome:R-HSA-8950505 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:1uy1zhroB3GHUiAwLjEdP5Rz1xM9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P40939 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q6N021 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-310727|uniprotkb:B5MDU0|uniprotkb:Q2TB88|uniprotkb:Q3LIB8|uniprotkb:Q96JX5|uniprotkb:Q9NXW0|uniprotkb:Q9HCM6|intact:EBI-2824636|ensembl:ENSP00000369351|ensembl:ENSP00000442788 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:tet2_human(display_long)|uniprotkb:TET2(gene name)|psi-mi:TET2(display_short)|uniprotkb:KIAA1546(gene name synonym)|uniprotkb:Nbla00191(orf name) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001120680.1|refseq:NP_060098.3|refseq:XP_005263139.1|ensembl:ENSG00000168769(gene)|ensembl:ENST00000380013(transcript)|ensembl:ENST00000540549(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006211"(5-methylcytosine catabolic process)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070579"(methylcytosine dioxygenase activity)|go:"GO:0070989"(oxidative demethylation)|go:"GO:0080111"(DNA demethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR024779|interpro:IPR040175|mint:Q6N021|rcsb pdb:4NM6|rcsb pdb:5D9Y|rcsb pdb:5DEU|reactome:R-HSA-5221030 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:/NfgfLFy2v4y6V3rTQ+CWo7Uq/49606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q92598 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:O75976 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-3916308|uniprotkb:B7Z7T9|uniprotkb:B7ZAU4|uniprotkb:F5GZH6|uniprotkb:Q86SH9|uniprotkb:O15377|uniprotkb:Q86XE6|ensembl:ENSP00000225719 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:cbpd_human(display_long)|uniprotkb:CPD(gene name)|psi-mi:CPD(display_short)|uniprotkb:Metallocarboxypeptidase D(gene name synonym)|uniprotkb:gp180(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001295.2|refseq:NP_001186704.1|interpro:IPR015567(Peptidase M14B, caboxypeptidase D unit2)|interpro:IPR033848|interpro:IPR034224|mint:O75976|rcsb pdb:5AQ0|reactome:R-HSA-432722|reactome:R-HSA-9696264|reactome:R-HSA-9696273|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|ensembl:ENSG00000108582(gene)|ensembl:ENST00000225719(transcript)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:PC6PFm4D7KoT4utNwyIe57VUwbY9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9NWZ8 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2626001|uniprotkb:C4AMC4|uniprotkb:Q2LJ66|uniprotkb:Q6ZV27|ensembl:ENSP00000369895|ensembl:ENSP00000381398|ensembl:ENSP00000505279|ensembl:ENSP00000505429 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:gemi8_human(display_long)|uniprotkb:GEMIN8(gene name)|psi-mi:GEMIN8(display_short)|uniprotkb:FAM51A1(gene name synonym)|uniprotkb:Protein FAM51A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001035944.1|refseq:NP_001035945.1|refseq:NP_060326.1|refseq:XP_016885106.1|refseq:XP_016885107.1|ensembl:ENSG00000046647(gene)|ensembl:ENST00000380523(transcript)|ensembl:ENST00000398355(transcript)|ensembl:ENST00000477386(transcript)|ensembl:ENST00000680255(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR034754|mint:Q9NWZ8|rcsb pdb:7BBL|reactome:R-HSA-191859 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Lvyive5mtL+89HujsYibFUTFP1k9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P62191 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P09493 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-351158|uniprotkb:P09494|uniprotkb:P10469|uniprotkb:Q86W64|uniprotkb:Q96IK2|uniprotkb:Q9Y427|uniprotkb:Q9UCY9|uniprotkb:Q6DV89|uniprotkb:Q6DV90|uniprotkb:Q9UCI1|uniprotkb:Q9UCI2|uniprotkb:B7Z5T7|uniprotkb:Q7Z6L8|intact:EBI-2558177|ensembl:ENSP00000385107|intact:EBI-11030042|uniprotkb:D9YZV2|uniprotkb:D9YZV3|uniprotkb:D9YZV8 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:tpm1_human(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_000357.3|refseq:NP_001018005.1|refseq:NP_001018006.1|refseq:NP_001018008.1|ensembl:ENSG00000140416(gene)|ensembl:ENST00000403994(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032059"(bleb)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000533(Tropomyosin)|mint:P09493|rcsb pdb:3MUD|rcsb pdb:5KHT|rcsb pdb:6UT2|rcsb pdb:6X5Z|reactome:R-HSA-390522|reactome:R-HSA-445355|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_001288173.1|refseq:NP_001018007.1|refseq:NP_001018004.1|refseq:NP_001018020.1|refseq:XP_016878027.1|refseq:NP_001317273.1|refseq:NP_001317275.1|refseq:NP_001317280.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:rsKuZnKpbEqVOpYBz3PnoSBCSHs9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P52907 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P0DP23 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-25817233|ensembl:ENSP00000349467|intact:EBI-28973196|uniprotkb:P02593|uniprotkb:P62158|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:calm1_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2LGF|rcsb pdb:2LL6|rcsb pdb:2LL7|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2LV6|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:2M55|rcsb pdb:2MG5|rcsb pdb:2N27|rcsb pdb:2N6A|rcsb pdb:2N77|rcsb pdb:2N8J|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2HF5|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902494"(catalytic complex)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P0DP23|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|go:"GO:0097718"(disordered domain specific binding)|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|ensembl:ENSG00000198668(gene)|ensembl:ENST00000356978(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030017"(sarcomere)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031432"(titin binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043209"(myelin sheath)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1UP5|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:1NKF|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2Y4V|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3J41|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3SUI|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4BYF|rcsb pdb:4DCK|rcsb pdb:4DJC|rcsb pdb:4GOW|rcsb pdb:4JPZ|rcsb pdb:4JQ0|rcsb pdb:4L79|rcsb pdb:4LZX|rcsb pdb:4M1L|rcsb pdb:4OVN|rcsb pdb:4Q57|rcsb pdb:4Q5U|rcsb pdb:4UMO|rcsb pdb:4UPU|rcsb pdb:4V0C|rcsb pdb:5COC|rcsb pdb:3BYA|rcsb pdb:5DBR|rcsb pdb:5DOW|rcsb pdb:5DSU|rcsb pdb:5GGM|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5J8H|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5K7L|rcsb pdb:5K8Q|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6BUT|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6FEG|rcsb pdb:6FEH|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6HR1|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6M2W|rcsb pdb:6M7H|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|rcsb pdb:6OS4|rcsb pdb:6PAW|rcsb pdb:6PBX|rcsb pdb:6PBY|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6X32|rcsb pdb:6X33|rcsb pdb:6X35|rcsb pdb:6X36|rcsb pdb:6XXX|rcsb pdb:6XY3|rcsb pdb:6XYR|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|rcsb pdb:6YNS|rcsb pdb:6YNU|rcsb pdb:6ZBI|rcsb pdb:7KL5|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-1474151|reactome:R-HSA-5210891|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-163615|reactome:R-HSA-180024|reactome:R-HSA-5576892|reactome:R-HSA-1855204|reactome:R-HSA-2025928|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-203615|reactome:R-HSA-2151201|reactome:R-HSA-2514859|reactome:R-HSA-5673000|reactome:R-HSA-2672351|reactome:R-HSA-5673001|reactome:R-HSA-6802946|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-70221|reactome:R-HSA-8876725|reactome:R-HSA-9009391|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|reactome:R-HSA-983695|reactome:R-HSA-442729|refseq:NP_001316851.1|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P26641 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q53RT3 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2371375|uniprotkb:Q8N5P2|uniprotkb:Q96LT3|uniprotkb:Q96N43|ensembl:ENSP00000315383 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:aprv1_human(display_long)|uniprotkb:ASPRV1(gene name)|psi-mi:ASPRV1(display_short)|uniprotkb:SASP(gene name synonym)|uniprotkb:Skin-specific retroviral-like aspartic protease(gene name synonym)|uniprotkb:TPA-inducible aspartic proteinase-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_690005.2|ensembl:ENSG00000244617(gene)|ensembl:ENST00000320256(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0043588"(skin development)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR001995(Peptidase A2A, retrovirus, catalytic)|interpro:IPR021109|interpro:IPR033539 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:V0lDtJGrezFxl6nhSrHJRE8t3+k9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P02545 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P04792 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N - - crc64:1B4DC44A6F6606D5 figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P13489 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P00338 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q01469 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:O14983 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-359186|uniprotkb:O14984|uniprotkb:A8K5J9|ensembl:ENSP00000349595|uniprotkb:B3KY17 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:at2a1_human(display_long)|uniprotkb:ATP2A1(gene name)|psi-mi:ATP2A1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_004311.1|refseq:NP_775293.1|ensembl:ENSG00000196296(gene)|ensembl:ENST00000357084(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034704"(calcium channel complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O14983|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001273004.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:3cHH/E8HuaFCoTd7hO/0SFTnqtg9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q13200 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P05164 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2556173|uniprotkb:Q14862|uniprotkb:Q9UCL7|uniprotkb:A1L4B8|uniprotkb:Q4PJH5|ensembl:ENSP00000225275 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:perm_human(display_long)|uniprotkb:MPO(gene name)|psi-mi:MPO(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_000241.1|ensembl:ENSG00000005381(gene)|go:"GO:0002149"(hypochlorous acid biosynthetic process)|go:"GO:0002679"(respiratory burst involved in defense response)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000225275(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0008201"(heparin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030141"(secretory granule)|go:"GO:0032094"(response to food)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042582"(azurophil granule)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1990268"(response to gold nanoparticle)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019791|interpro:IPR029609|interpro:IPR037120|mint:P05164|rcsb pdb:1CXP|rcsb pdb:1D2V|rcsb pdb:1D5L|rcsb pdb:1D7W|rcsb pdb:1DNU|rcsb pdb:1DNW|rcsb pdb:1MHL|rcsb pdb:1MYP|rcsb pdb:3F9P|rcsb pdb:3ZS0|rcsb pdb:3ZS1|rcsb pdb:4C1M|rcsb pdb:4DL1|rcsb pdb:4EJX|rcsb pdb:5FIW|rcsb pdb:5MFA|rcsb pdb:5UZU|rcsb pdb:6AZP|rcsb pdb:6BMT|reactome:R-HSA-6798695|reactome:R-HSA-8941413 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:SNoAXb3csr/iOyGWeyWcUyJTZLY9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P30740 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2831526|uniprotkb:Q53FB9|uniprotkb:A8K5L2|uniprotkb:Q5W0E1|uniprotkb:Q9UDF8|uniprotkb:B4DNT0|ensembl:ENSP00000370115 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ileu_human(display_long)|uniprotkb:SERPINB1(gene name)|psi-mi:SERPINB1(display_short)|uniprotkb:ELANH2(gene name synonym)|uniprotkb:MNEI(gene name synonym)|uniprotkb:PI2(gene name synonym)|uniprotkb:Monocyte/neutrophil elastase inhibitor(gene name synonym)|uniprotkb:Peptidase inhibitor 2(gene name synonym)|uniprotkb:Serpin B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:XP_011512635.1|refseq:XP_011512636.1|ensembl:ENSG00000021355(gene)|ensembl:ENST00000380739(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015557(Protease inhibitor I4, serpin B1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:4GA7|reactome:R-HSA-6798695|refseq:NP_109591.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:5IolAmA+BrS4XHZZEQgf05kA4pE9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P31040 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q96HE7 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2564539|uniprotkb:A8K9X4|uniprotkb:A8MYW1|uniprotkb:Q7LD45|uniprotkb:Q9P1Q9|uniprotkb:Q9UKV6|ensembl:ENSP00000379042 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ero1a_human(display_long)|uniprotkb:ERO1A(gene name)|psi-mi:ERO1A(display_short)|uniprotkb:ERO1L(gene name synonym)|uniprotkb:Endoplasmic oxidoreductin-1-like protein(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductase alpha(gene name synonym)|uniprotkb:Oxidoreductin-1-L-alpha(gene name synonym)|uniprotkb:UNQ434/PRO865(orf name) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_055399.1|ensembl:ENSG00000197930(gene)|ensembl:ENST00000395686(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0010260"(animal organ senescence)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030425"(dendrite)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071949"(FAD binding)|interpro:IPR007266(Endoplasmic reticulum oxidoreductin 1)|interpro:IPR037192|mint:Q96HE7|rcsb pdb:3AHQ|rcsb pdb:3AHR|reactome:R-HSA-264876|reactome:R-HSA-3299685 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:7IOP99IQt+7MBAQ0LKqPo5mFylo9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q92841 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P02786 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q08J23 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q13263 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P78527 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P50416 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2817330|uniprotkb:Q9BWK0|uniprotkb:Q8TCU0|ensembl:ENSP00000265641|ensembl:ENSP00000446108 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:cpt1a_human(display_long)|uniprotkb:CPT1A(gene name)|psi-mi:CPT1A(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine O-palmitoyltransferase I, liver isoform(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001027017.1|refseq:NP_001867.2|refseq:XP_016872709.1|ensembl:ENSG00000110090(gene)|ensembl:ENST00000265641(transcript)|ensembl:ENST00000539743(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0045471"(response to ethanol)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097421"(liver regeneration)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990698"(palmitoleoyltransferase activity)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR032476|interpro:IPR039551|interpro:IPR042231|mint:P50416|rcsb pdb:2LE3|reactome:R-HSA-1368082|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-5362517 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:fmB4d9VHyWPyV0uTf00NkOr/fM49606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q8NF50 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2548605|uniprotkb:B7ZLP0|uniprotkb:E9PH09|ensembl:ENSP00000394888|uniprotkb:A2A350|uniprotkb:A2BDF2|uniprotkb:A4FU78|uniprotkb:Q3MV16|uniprotkb:Q5JPJ1|uniprotkb:Q8TEP1|uniprotkb:Q8WUY2|uniprotkb:Q9BYJ5|uniprotkb:Q9H1Q2|uniprotkb:Q9H1Q3|uniprotkb:Q9H308|uniprotkb:Q9H7P2|intact:EBI-11070681 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:dock8_human(display_long)|uniprotkb:DOCK8(gene name)|psi-mi:DOCK8(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:XP_011516347.1|refseq:XP_011516349.1|ensembl:ENSG00000107099(gene)|ensembl:ENST00000432829(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0061485"(memory T cell proliferation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021816|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR035892|interpro:IPR037808|interpro:IPR043161|interpro:IPR043162|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-983231|refseq:XP_011516350.1|refseq:NP_001177387.1|refseq:NP_001180465.1|refseq:NP_982272.2|refseq:XP_016870662.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:4ENO+3IOKfCUicfg8fxFQbwf4fg9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P17812 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1042983|uniprotkb:Q5VW67|uniprotkb:Q96GK6|ensembl:ENSP00000361699|ensembl:ENSP00000497602|ensembl:ENSP00000497744|uniprotkb:D3DPW1|uniprotkb:B4DR64 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:pyrg1_human(display_long)|uniprotkb:CTPS1(gene name)|psi-mi:CTPS1(display_short)|uniprotkb:CTP synthetase 1(gene name synonym)|uniprotkb:CTPS(gene name synonym)|uniprotkb:UTP--ammonia ligase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000171793(gene)|ensembl:ENST00000372616(transcript)|ensembl:ENST00000649124(transcript)|ensembl:ENST00000650070(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|mint:P17812|rcsb pdb:2VO1|rcsb pdb:5U03|reactome:R-HSA-499943|refseq:NP_001288166.1|refseq:NP_001896.2 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:0QkxA3YRejXU0X7dk7zf1XeAMt89606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P40227 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P46977 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P15170 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P11413 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-4289891|uniprotkb:Q8IU88|uniprotkb:D3DWX9|uniprotkb:Q16000|uniprotkb:Q16765|uniprotkb:Q8IUA6|uniprotkb:Q8IU70|uniprotkb:Q96PQ2|ensembl:ENSP00000377192|ensembl:ENSP00000377194 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:g6pd_human(display_long)|uniprotkb:G6PD(gene name)|psi-mi:G6PD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_000393.4|refseq:NP_001035810.1|ensembl:ENSG00000160211(gene)|ensembl:ENST00000393562(transcript)|ensembl:ENST00000393564(transcript)|go:"GO:0004345"(glucose-6-phosphate dehydrogenase activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010041"("response to iron(III) ion")|go:"GO:0010734"(negative regulation of protein glutathionylation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032094"(response to food)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022674|interpro:IPR022675|interpro:IPR036291|rcsb pdb:1QKI|rcsb pdb:2BH9|rcsb pdb:2BHL|rcsb pdb:5UKW|rcsb pdb:6E07|rcsb pdb:6E08|rcsb pdb:6JYU|rcsb pdb:6VA0|rcsb pdb:6VA7|rcsb pdb:6VA8|rcsb pdb:6VA9|rcsb pdb:6VAQ|reactome:R-HSA-5628897|reactome:R-HSA-71336 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:qW8uk6xBGtrxlsosIH6gEG1ZfWA9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q14739 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:O00571 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P23588 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9P258 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-352547|uniprotkb:Q8IVL9|uniprotkb:Q9BSN6|uniprotkb:Q9NPV8|ensembl:ENSP00000364582|ensembl:ENSP00000364585|ensembl:ENSP00000486099|ensembl:ENSP00000486447 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:rcc2_human(display_long)|uniprotkb:RCC2(gene name)|psi-mi:RCC2(display_short)|uniprotkb:KIAA1470(gene name synonym)|uniprotkb:TD60(gene name synonym)|uniprotkb:Telophase disk protein of 60 kDa(gene name synonym)|uniprotkb:RCC1-like protein TD-60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001129676.1|refseq:NP_061185.1|ensembl:ENSG00000179051(gene)|ensembl:ENSG00000281540(gene)|ensembl:ENST00000375433(transcript)|ensembl:ENST00000375436(transcript)|ensembl:ENST00000628984(transcript)|ensembl:ENST00000631021(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051301"(cell division)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072356"(chromosome passenger complex localization to kinetochore)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR028641|mint:Q9P258|rcsb pdb:5GWN|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:z9+0avftBLs4Q3ODFHLEmJtd57A9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P27824 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q99497 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1164361|uniprotkb:O14805|uniprotkb:Q6DR95|uniprotkb:Q7LFU2|uniprotkb:B2R4Z1|ensembl:ENSP00000340278|ensembl:ENSP00000366708|ensembl:ENSP00000366711|ensembl:ENSP00000418770|ensembl:ENSP00000465404 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:park7_human(display_long)|uniprotkb:PARK7(gene name)|psi-mi:PARK7(display_short)|uniprotkb:Oncogene DJ1(gene name synonym)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Maillard deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001116849.1|refseq:NP_009193.2|refseq:XP_005263481.1|go:"GO:0046295"(glycolate biosynthetic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050787"(detoxification of mercury ion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061727"(methylglyoxal catabolic process to lactate)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098793"(presynapse)|go:"GO:0106044"(guanine deglycation)|go:"GO:0106045"(guanine deglycation, methylglyoxal removal)|go:"GO:0106046"(guanine deglycation, glyoxal removal)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:0140041"(cellular detoxification of methylglyoxal)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902903"(regulation of supramolecular fiber organization)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1903073"(negative regulation of death-inducing signaling complex assembly)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1903122"(negative regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1903168"(positive regulation of pyrroline-5-carboxylate reductase activity)|go:"GO:1903178"(positive regulation of tyrosine 3-monooxygenase activity)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903189"(glyoxal metabolic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1903200"(positive regulation of L-dopa decarboxylase activity)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903384"(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990422"("glyoxalase (glycolic acid-forming) activity")|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR002818(ThiJ/PfpI)|interpro:IPR006287(DJ-1)|interpro:IPR029062|go:"GO:1903197"(positive regulation of L-dopa biosynthetic process)|rcsb pdb:3B36|rcsb pdb:3B38|rcsb pdb:3B3A|rcsb pdb:3BWE|rcsb pdb:3CY6|rcsb pdb:3CYF|rcsb pdb:3CZ9|rcsb pdb:3CZA|rcsb pdb:3EZG|mint:Q99497|rcsb pdb:1J42|rcsb pdb:1P5F|rcsb pdb:3F71|rcsb pdb:1PDV|rcsb pdb:1PDW|rcsb pdb:1PE0|rcsb pdb:1Q2U|rcsb pdb:3SF8|rcsb pdb:1SOA|rcsb pdb:1UCF|rcsb pdb:2OR3|rcsb pdb:2R1T|rcsb pdb:2R1U|rcsb pdb:2R1V|rcsb pdb:4BTE|rcsb pdb:2RK3|rcsb pdb:2RK4|rcsb pdb:2RK6|ensembl:ENSG00000116288(gene)|ensembl:ENST00000338639(transcript)|ensembl:ENST00000377488(transcript)|ensembl:ENST00000377491(transcript)|ensembl:ENST00000493678(transcript)|ensembl:ENST00000493373(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002866"(positive regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006281"(DNA repair)|rcsb pdb:4MTC|rcsb pdb:4N0M|rcsb pdb:4N12|rcsb pdb:4OGF|rcsb pdb:4OQ4|rcsb pdb:4P2G|rcsb pdb:4P34|rcsb pdb:4P35|rcsb pdb:4P36|rcsb pdb:4RKW|rcsb pdb:4RKY|rcsb pdb:4S0Z|rcsb pdb:4ZGG|rcsb pdb:5IP5|rcsb pdb:5SY6|rcsb pdb:5SY9|rcsb pdb:5SYA|rcsb pdb:6AF5|rcsb pdb:6AF7|rcsb pdb:6AF9|rcsb pdb:6AFA|rcsb pdb:6AFB|rcsb pdb:6AFC|rcsb pdb:6AFD|rcsb pdb:6AFE|rcsb pdb:6AFF|rcsb pdb:6AFG|rcsb pdb:6AFH|rcsb pdb:6AFI|rcsb pdb:6AFJ|rcsb pdb:6AFL|rcsb pdb:6E5Z|rcsb pdb:6M8Z|rcsb pdb:7C62|reactome:R-HSA-3899300|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|rcsb pdb:4MNT|go:"GO:0006517"(protein deglycosylation)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007338"(single fertilization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016532"(superoxide dismutase copper chaperone activity)|go:"GO:0016570"(histone modification)|go:"GO:0016605"(PML body)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0030424"(axon)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0036470"(tyrosine 3-monooxygenase activator activity)|go:"GO:0036471"(cellular response to glyoxal)|go:"GO:0036478"(L-dopa decarboxylase activator activity)|go:"GO:0036524"(protein deglycase activity)|go:"GO:0036526"(peptidyl-cysteine deglycation)|go:"GO:0036527"(peptidyl-arginine deglycation)|go:"GO:0036528"(peptidyl-lysine deglycation)|go:"GO:0036529"(protein deglycation, glyoxal removal)|go:"GO:0036530"(protein deglycation, methylglyoxal removal)|go:"GO:0036531"(glutathione deglycation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0030073"(insulin secretion)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045340"(mercury ion binding)|dip:DIP-35515N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:i5ah4UPCf+4cD51ClZNggMFJMDo9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y4W6 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-358755|uniprotkb:Q6P1L0|ensembl:ENSP00000269143 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:afg32_human(display_long)|uniprotkb:AFG3L2(gene name)|psi-mi:AFG3L2(display_short)|uniprotkb:Paraplegin-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000141385(gene)|ensembl:ENST00000269143(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|refseq:NP_006787.2|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q9Y4W6|rcsb pdb:2LNA|rcsb pdb:6NYY|reactome:R-HSA-8949664 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:5S4ucntvmQpRTehJ0QBEAYsGN089606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P16615 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q13098 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-725197|uniprotkb:Q8NA10|uniprotkb:Q9BWL1|ensembl:ENSP00000302873 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:csn1_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 1(gene name synonym)|uniprotkb:G protein pathway suppressor 1(gene name synonym)|uniprotkb:Protein MFH(gene name synonym)|uniprotkb:GPS1(gene name)|psi-mi:GPS1(display_short)|uniprotkb:COPS1(gene name synonym)|uniprotkb:CSN1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_004118.3|refseq:NP_997657.1|ensembl:ENSG00000169727(gene)|ensembl:ENST00000306823(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR019585|interpro:IPR033008|interpro:IPR036390|mint:Q13098|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|go:"GO:0005829"(cytosol)|go:"GO:0007254"(JNK cascade)|go:"GO:0008180"(COP9 signalosome)|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|refseq:NP_001308021.1|refseq:XP_016880023.1|dip:DIP-42077N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:OMWZ67qcgKTM0R/hy8L2oCa3cpo9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P42704 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P49247 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y3Z3 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P30566 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2511688|ensembl:ENSP00000485525|uniprotkb:B0QY76|uniprotkb:O75495|uniprotkb:Q5TI34 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:pur8_human(display_long)|uniprotkb:ADSL(gene name)|psi-mi:ADSL(display_short)|uniprotkb:AMPS(gene name synonym)|uniprotkb:Adenylosuccinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 go:"GO:0014850"(response to muscle activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0070626"("(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity")|ensembl:ENSG00000239900(gene)|ensembl:ENST00000623063(transcript)|interpro:IPR000362(Fumarate lyase)|interpro:IPR004769(Adenylosuccinate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR019468|interpro:IPR020557|interpro:IPR022761|rcsb pdb:2J91|rcsb pdb:2VD6|rcsb pdb:4FFX|rcsb pdb:4FLC|reactome:R-HSA-73817|go:"GO:0001666"(response to hypoxia)|go:"GO:0004018"("N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009060"(aerobic respiration)|refseq:NP_000017.1|refseq:NP_001116850.1|refseq:NP_001304852.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:yBhDdHJgZN1NJDpN2ivKLI4oUG09606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:O43865 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|uniprotkb:B4E168|ensembl:ENSP00000358814 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:"IP(3)Rs binding protein released with IP(3)"(gene name synonym)|uniprotkb:IRBIT(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|ensembl:ENSG00000168710(gene)|ensembl:ENST00000369799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P32119 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q92817 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-3447371|uniprotkb:A0AUV5|ensembl:ENSP00000301607 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:evpl_human(display_long)|uniprotkb:EVPL(gene name)|psi-mi:EVPL(display_short)|uniprotkb:210 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:210 kDa paraneoplastic pemphigus antigen(gene name synonym)|uniprotkb:p210(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001307676.1|refseq:NP_001979.2|ensembl:ENSG00000167880(gene)|ensembl:ENST00000301607(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR030460|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|mint:Q92817|rcsb pdb:4QMD|reactome:R-HSA-6809371|go:"GO:0018149"(peptide cross-linking) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:KPm64OC6taugW179BA0vT7JEt9U9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q96JJ7 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y446 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2880227|ensembl:ENSP00000331678|uniprotkb:F8J390|uniprotkb:Q53EX8 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:pkp3_human(display_long)|uniprotkb:PKP3(gene name)|psi-mi:PKP3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000184363(gene)|ensembl:ENST00000331563(transcript)|go:"GO:0002159"(desmosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006417"(regulation of translation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0001533"(cornified envelope)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028434|interpro:IPR028435|mint:Q9Y446|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|refseq:NP_001289958.1|refseq:NP_009114.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:zGNbdze5MA5Mnf8m9IWZsxAPjAQ9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P61019 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-752037|uniprotkb:P08886|uniprotkb:B2R5W8|uniprotkb:B4DMQ5|ensembl:ENSP00000262646 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:rab2a_human(display_long)|uniprotkb:RAB2A(gene name)|psi-mi:RAB2A(display_short)|uniprotkb:RAB2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_002856.1|refseq:NP_001229573.1|dip:DIP-316N|ensembl:ENSG00000104388(gene)|ensembl:ENST00000262646(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1Z0A|reactome:R-HSA-162658|reactome:R-HSA-8873719 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:MyG011KOkAtsvE2hU/fs21CEe/M9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9UK59 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2871803|uniprotkb:Q96GH0|uniprotkb:Q9NXQ6|ensembl:ENSP00000260803 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:dbr1_human(display_long)|uniprotkb:DBR1(gene name)|psi-mi:DBR1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_057300.2|ensembl:ENSG00000138231(gene)|ensembl:ENST00000260803(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008419"(RNA lariat debranching enzyme activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007708(Lariat debranching enzyme, C-terminal)|interpro:IPR029052|interpro:IPR041816 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:1Fg4qVuNHTGzcaV68f4ulwQ/GEw9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y4E8 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P12814 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:guTURyt26f1ort4NAlYyabNc+WE9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P25311 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2513837|ensembl:ENSP00000292401|uniprotkb:Q5XKQ4|uniprotkb:O60386|uniprotkb:Q8N4N0|uniprotkb:D6W5T8 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:za2g_human(display_long)|uniprotkb:AZGP1(gene name)|psi-mi:AZGP1(display_short)|uniprotkb:ZAG(gene name synonym)|uniprotkb:ZNGP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000160862(gene)|ensembl:ENST00000292401(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|interpro:IPR036179|interpro:IPR037055|mint:P25311|rcsb pdb:1T7V|rcsb pdb:1T7W|rcsb pdb:1T7X|rcsb pdb:1T7Y|rcsb pdb:1T7Z|rcsb pdb:1T80|rcsb pdb:1ZAG|rcsb pdb:3ES6|rcsb pdb:6R2U|reactome:R-HSA-5223345|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001176.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:3Fp6qALNiZRqsI8Kh2lTQ9IMYek9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P50395 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P58107 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-297954|uniprotkb:Q76E58|ensembl:ENSP00000484472|uniprotkb:A0A087X1U6|uniprotkb:Q9NSU9 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:epipl_human(display_long)|uniprotkb:EPPK1(gene name)|psi-mi:EPPK1(display_short)|uniprotkb:EPIPL(gene name synonym)|uniprotkb:450 kDa epidermal antigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSP00000484472|ensembl:ENSG00000261150(gene)|ensembl:ENST00000615648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042060"(wound healing)|go:"GO:0042995"(cell projection)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051548"(negative regulation of keratinocyte migration)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0071944"(cell periphery)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1905041"(regulation of epithelium regeneration)|go:"GO:1990254"(keratin filament binding)|interpro:IPR001101(Plectin repeat)|interpro:IPR035915|interpro:IPR043197|refseq:NP_112598.3|refseq:XP_016869379.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:5ThrRQj4JeRG4xjZxMgueWUrjuA9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P30041 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2255129|uniprotkb:A8JZY7|uniprotkb:P32077|uniprotkb:Q5TAH4|uniprotkb:Q5ZEZ8|ensembl:ENSP00000342026 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:prdx6_human(display_long)|uniprotkb:PRDX6(gene name)|psi-mi:PRDX6(display_short)|uniprotkb:AOP2(gene name synonym)|uniprotkb:KIAA0106(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:24 kDa protein(gene name synonym)|uniprotkb:Liver 2D page spot 40(gene name synonym)|uniprotkb:Red blood cells page spot 12(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_004896.1|ensembl:ENSG00000117592(gene)|ensembl:ENST00000340385(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:1PRX|rcsb pdb:5B6M|rcsb pdb:5B6N|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0042744"(hydrogen peroxide catabolic process) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:ZMsHgrAJf0VJiCELzo+zSi8Ji+49606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y2P8 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-11026509|uniprotkb:Q9NY00|uniprotkb:Q5VYW9|uniprotkb:Q9P044|uniprotkb:Q9H9D0|uniprotkb:D3DRI2|uniprotkb:Q5VZU1|ensembl:ENSP00000371169 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:rcl1_human(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RNAC(gene name synonym)|uniprotkb:RPC2(gene name synonym)|uniprotkb:RPCL1(gene name synonym)|uniprotkb:RTC2(gene name synonym)|uniprotkb:HSPC338(orf name) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001273628.1|refseq:NP_001273629.1|refseq:NP_001273630.1|refseq:NP_005763.3|refseq:XP_011515975.1|ensembl:ENSG00000120158(gene)|ensembl:ENST00000381750(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|mint:Q9Y2P8|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:XP_016869665.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:8WnLDVPrx4t1eD6h+emL5waEyDY9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:O60437 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q6ZVX7 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2877737|ensembl:ENSP00000342137|uniprotkb:Q6NVV5 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:fbx50_human(display_long)|uniprotkb:NCCRP1(gene name)|psi-mi:NCCRP1(display_short)|uniprotkb:FBXO50(gene name synonym)|uniprotkb:NCC receptor protein 1 homolog(gene name synonym)|uniprotkb:Non-specific cytotoxic cell receptor protein 1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000188505(gene)|ensembl:ENST00000339852(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR039752|refseq:NP_001001414.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Gj02wJIGGIYTIMxQmqn5rIePVLQ9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P07355 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q15149 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P17931 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1170392|uniprotkb:Q16005|uniprotkb:Q96J47|uniprotkb:B2RC38|uniprotkb:Q6IBA7|ensembl:ENSP00000254301 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:leg3_human(display_long)|uniprotkb:LGALS3(gene name)|psi-mi:LGALS3(display_short)|uniprotkb:MAC2(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:L-31(gene name synonym)|uniprotkb:Galactoside-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_002297.2|ensembl:ENSG00000131981(gene)|ensembl:ENST00000254301(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|mint:P17931|rcsb pdb:1A3K|rcsb pdb:1KJL|rcsb pdb:1KJR|rcsb pdb:2NMN|rcsb pdb:2NMO|rcsb pdb:2NN8|rcsb pdb:2XG3|rcsb pdb:3AYA|rcsb pdb:3AYC|rcsb pdb:3AYD|rcsb pdb:3AYE|rcsb pdb:3T1L|rcsb pdb:3T1M|rcsb pdb:3ZSJ|rcsb pdb:3ZSK|rcsb pdb:3ZSL|rcsb pdb:3ZSM|rcsb pdb:4BLI|rcsb pdb:4BLJ|rcsb pdb:4BM8|rcsb pdb:4JC1|rcsb pdb:4JCK|rcsb pdb:4LBJ|rcsb pdb:4LBK|rcsb pdb:4LBL|rcsb pdb:4LBM|rcsb pdb:4LBN|rcsb pdb:4LBO|rcsb pdb:4R9A|rcsb pdb:4R9B|rcsb pdb:4R9C|rcsb pdb:4R9D|rcsb pdb:4RL7|rcsb pdb:4XBN|rcsb pdb:5E88|rcsb pdb:5E89|rcsb pdb:5E8A|rcsb pdb:5EXO|rcsb pdb:5H9P|rcsb pdb:5H9R|rcsb pdb:5IUQ|rcsb pdb:5NF7|rcsb pdb:5NF9|rcsb pdb:5NFA|rcsb pdb:5NFB|rcsb pdb:5NFC|rcsb pdb:5OAX|rcsb pdb:5ODY|rcsb pdb:6B8K|rcsb pdb:6EOG|rcsb pdb:6EOL|rcsb pdb:6EXY|rcsb pdb:6EYM|rcsb pdb:6F2Q|rcsb pdb:6F6Y|rcsb pdb:6FK2|rcsb pdb:6FOF|rcsb pdb:6G0V|rcsb pdb:6H64|rcsb pdb:6I74|rcsb pdb:6I75|rcsb pdb:6I76|rcsb pdb:6I77|rcsb pdb:6I78|rcsb pdb:6KXA|rcsb pdb:6KXB|rcsb pdb:6Q0Q|rcsb pdb:6Q17|rcsb pdb:6QGE|rcsb pdb:6QGF|rcsb pdb:6QLN|rcsb pdb:6QLO|rcsb pdb:6QLP|rcsb pdb:6QLQ|rcsb pdb:6QLR|rcsb pdb:6QLS|rcsb pdb:6QLT|rcsb pdb:6QLU|rcsb pdb:6RHL|rcsb pdb:6RHM|rcsb pdb:6RZF|rcsb pdb:6RZG|rcsb pdb:6RZH|rcsb pdb:6RZI|rcsb pdb:6RZJ|rcsb pdb:6RZK|rcsb pdb:6RZL|rcsb pdb:6RZM|rcsb pdb:6TF6|rcsb pdb:6TF7|rcsb pdb:6Y4C|rcsb pdb:6Y78|rcsb pdb:6ZVF|rcsb pdb:7BE3|rcsb pdb:7DF5|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-8939246|reactome:R-HSA-8941333|dip:DIP-45623N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:5FijxEN6irEGIg4AtAdn6DB03e49606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9UNS2 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q02487 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-3048545|ensembl:ENSP00000280904 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:dsc2_human(display_long)|uniprotkb:DSC2(gene name)|psi-mi:DSC2(display_short)|uniprotkb:CDHF2(gene name synonym)|uniprotkb:DSC3(gene name synonym)|uniprotkb:Cadherin family member 2(gene name synonym)|uniprotkb:Desmocollin-3(gene name synonym)|uniprotkb:Desmosomal glycoprotein II(gene name synonym)|uniprotkb:Desmosomal glycoprotein III(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000134755(gene)|ensembl:ENST00000280904(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0014704"(intercalated disc)|go:"GO:0030057"(desmosome)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086042"(cardiac muscle cell-cardiac muscle cell adhesion)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|go:"GO:0016021"(integral component of membrane)|rcsb pdb:5ERP|interpro:IPR027397|rcsb pdb:5J5J|rcsb pdb:7A7D|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_004940.1|refseq:NP_077740.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:EUXe5KbkWaO5wRalhRX+pf7jkOQ9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P51571 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P09211 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q96CG3 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-740711|ensembl:ENSP00000354911|ensembl:ENSP00000424231 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:tifa_human(display_long)|uniprotkb:Putative NF-kappa-B-activating protein 20(gene name synonym)|uniprotkb:TIFA(gene name)|psi-mi:TIFA(display_short)|uniprotkb:T2BP(gene name synonym)|uniprotkb:TRAF2-binding protein(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_443096.1|ensembl:ENSG00000145365(gene)|ensembl:ENST00000361717(transcript)|ensembl:ENST00000500655(transcript)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|rcsb pdb:4YM4|rcsb pdb:4ZGI|rcsb pdb:5ZUJ|rcsb pdb:6A33|reactome:R-HSA-9645460|dip:DIP-40185N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:ppKFaTK8YYWSscDQlE1n/mONziY9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P51149 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y3R4 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-10327976|uniprotkb:Q6NTB4|uniprotkb:Q3KNW4|ensembl:ENSP00000233840 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:neur2_human(display_long)|uniprotkb:NEU2(gene name)|psi-mi:NEU2(display_short)|uniprotkb:Cytosolic sialidase(gene name synonym)|uniprotkb:N-acetyl-alpha-neuraminidase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_005374.2|ensembl:ENSG00000115488(gene)|ensembl:ENST00000233840(transcript)|go:"GO:0004308"(exo-alpha-sialidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006689"(ganglioside catabolic process)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051692"(cellular oligosaccharide catabolic process)|go:"GO:0052794"("exo-alpha-(2->3)-sialidase activity")|go:"GO:0052795"("exo-alpha-(2->6)-sialidase activity")|go:"GO:0052796"("exo-alpha-(2->8)-sialidase activity")|go:"GO:1902494"(catalytic complex)|interpro:IPR011040(Neuraminidase)|interpro:IPR026856|interpro:IPR026945|interpro:IPR036278|rcsb pdb:1SNT|rcsb pdb:1SO7|rcsb pdb:1VCU|rcsb pdb:2F0Z|rcsb pdb:2F10|rcsb pdb:2F11|rcsb pdb:2F12|rcsb pdb:2F13|rcsb pdb:2F24|rcsb pdb:2F25|rcsb pdb:2F26|rcsb pdb:2F27|rcsb pdb:2F28|rcsb pdb:2F29|rcsb pdb:4NC5|rcsb pdb:4NCS|reactome:R-HSA-1660662|reactome:R-HSA-4085001 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:sbr+gscI37hqYirl/qEGssh6Wdg9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9NR30 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q5VVQ6 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2510804|ensembl:ENSP00000326813|uniprotkb:Q86T63|uniprotkb:B2RNX3|uniprotkb:Q5VVQ5|uniprotkb:Q9P1L8|uniprotkb:Q6ZRS6 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:otu1_human(display_long)|uniprotkb:YOD1(gene name)|psi-mi:YOD1(display_short)|uniprotkb:DUBA8(gene name synonym)|uniprotkb:HIN7(gene name synonym)|uniprotkb:OTUD2(gene name synonym)|uniprotkb:OTU domain-containing protein 2(gene name synonym)|uniprotkb:DUBA-8(gene name synonym)|uniprotkb:HIV-1-induced protease 7(gene name synonym)|uniprotkb:PRO0907(orf name) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 rcsb pdb:4BOZ|reactome:R-HSA-5689896|rcsb pdb:4BOS|ensembl:ENSG00000180667(gene)|ensembl:ENST00000315927(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016236"(macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035523"(protein K29-linked deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990168"(protein K33-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029071|interpro:IPR038765|interpro:IPR039138|rcsb pdb:4BOQ|refseq:NP_001263249.1|refseq:NP_061036.3 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:ulHudY1eLmIPQKfgdkXNoE1O5AM9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P36952 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-2371394|uniprotkb:B2R6Y4|uniprotkb:Q6N0B4|uniprotkb:Q8WW89|ensembl:ENSP00000372221 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:spb5_human(display_long)|uniprotkb:SERPINB5(gene name)|psi-mi:SERPINB5(display_short)|uniprotkb:PI5(gene name synonym)|uniprotkb:Peptidase inhibitor 5(gene name synonym)|uniprotkb:Maspin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_002630.2|ensembl:ENSG00000206075(gene)|ensembl:ENST00000382771(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0060512"(prostate gland morphogenesis)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR000240(Serpin B9 and maspin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033836|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P36952|rcsb pdb:1WZ9|rcsb pdb:1XQG|rcsb pdb:1XQJ|rcsb pdb:1XU8 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:p2g5mTsqtSjgS73Zvoy64BV5Zes9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P05141 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q14134 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9NTK5 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|uniprotkb:D7EHM2|ensembl:ENSP00000284719 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENST00000284719(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|ensembl:ENSG00000138430(gene) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9Y3F4 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-727414|uniprotkb:Q9UQC8|uniprotkb:Q9NTK0|uniprotkb:Q5TZT4|intact:EBI-6190807|uniprotkb:B4DNJ6|uniprotkb:B2R5S5|ensembl:ENSP00000392270 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:strap_human(display_long)|uniprotkb:UNR-interacting protein(gene name synonym)|uniprotkb:WD-40 repeat protein PT-WD(gene name synonym)|uniprotkb:MAP activator with WD repeats(gene name synonym)|uniprotkb:STRAP(gene name)|psi-mi:STRAP(display_short)|uniprotkb:MAWD(gene name synonym)|uniprotkb:UNRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_009109.3|ensembl:ENSG00000023734(gene)|ensembl:ENST00000419869(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Y3F4|reactome:R-HSA-2173788 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:/IqZt6BHPxD3S/THUZry4+QUvCE9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P50452 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-6916752|uniprotkb:B4DTW2|uniprotkb:Q7Z2V6|uniprotkb:Q8N178|ensembl:ENSP00000331368|ensembl:ENSP00000381072 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:spb8_human(display_long)|uniprotkb:SERPINB8(gene name)|psi-mi:SERPINB8(display_short)|uniprotkb:PI8(gene name synonym)|uniprotkb:Cytoplasmic antiproteinase 2(gene name synonym)|uniprotkb:Peptidase inhibitor 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001027018.1|refseq:NP_001263419.1|refseq:NP_002631.3|refseq:NP_942130.1|ensembl:ENSG00000166401(gene)|ensembl:ENST00000353706(transcript)|ensembl:ENST00000397985(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|reactome:R-HSA-75205 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:8zDKTATO2nW9OagEjG5BmtJcRxQ9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P15531 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:Q9BT78 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|ensembl:ENSP00000264389|uniprotkb:B3KST5 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000138663(gene)|refseq:NP_057213.2|refseq:NP_001244935.1|go:"GO:0016607"(nuclear speck)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|ensembl:ENST00000264389(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|refseq:NP_001317656.1|dip:DIP-34516N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P49411 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P04083 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P30048 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P12235 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6ZNK6 uniprotkb:P27482 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-747537|uniprotkb:Q5SQI4|uniprotkb:B2R9V6|ensembl:ENSP00000315299 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:call3_human(display_long)|uniprotkb:Calmodulin-related protein NB-1(gene name synonym)|uniprotkb:CaM-like protein(gene name synonym)|uniprotkb:CALML3(gene name)|psi-mi:CALML3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453464|imex:IM-28520-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 refseq:NP_005176.1|ensembl:ENSG00000178363(gene)|ensembl:ENST00000315238(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P27482|rcsb pdb:1GGZ - - - figure legend:Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:7yRRBYvsbUxzIvnYaNmaIJ42i5Y9606 rigid:VHDGgNmok2rzMxnvC6VZVMT7K+E false flag tag:?-?|ha tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y4E8 uniprotkb:Q6ZNK6 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453624|imex:IM-28520-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 - - - figure legend:Fig. 1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hl_60)|taxid:9606(Homo sapiens acute myeloid leukemia cell line) - 2020/11/23 2020/11/24 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rigid:0kKdW5x4n7/hER1q0Nbn46Yt7oY false - flag tag:?-?|ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y4E8 uniprotkb:Q6ZNK6 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453653|imex:IM-28520-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 - - - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/11/23 2020/11/24 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rigid:0kKdW5x4n7/hER1q0Nbn46Yt7oY false sufficient binding region:1-583|flag tag:n-n|sufficient binding region:470-981|necessary binding region:1-113 ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y4E8 uniprotkb:Q6ZNK6 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26453691|imex:IM-28520-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 - - - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/11/23 2020/11/24 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rigid:0kKdW5x4n7/hER1q0Nbn46Yt7oY false mutation decreasing interaction strength:298-298|ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-4399559 intact:EBI-4399559 dip:DIP-24261N dip:DIP-24261N psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0998"(deubiquitinase assay) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0204"(deubiquitination reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26453710|imex:IM-28520-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 go:"GO:0004843"(thiol-dependent deubiquitinase) no-uniprot-update: no-uniprot-update: figure legend:Fig.2C,2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/11/23 2020/11/24 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:60F6+1Z8gKcxQ4CM8/L41dJlS/Y false binding-associated region:?-?|fluorescent dye label:?-? binding-associated region:?-?|tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) intact:EBI-4399559 uniprotkb:Q9Y4E8 dip:DIP-24261N intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:"MI:0998"(deubiquitinase assay) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0204"(deubiquitination reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26453710|imex:IM-28520-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N go:"GO:0004843"(thiol-dependent deubiquitinase) no-uniprot-update: - figure legend:Fig.2C,2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/11/23 2020/11/24 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rigid:60F6+1Z8gKcxQ4CM8/L41dJlS/Y false binding-associated region:?-?|fluorescent dye label:?-? his tag:?-?|sumo tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q6ZNK6 intact:EBI-4399559 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 dip:DIP-24261N psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0998"(deubiquitinase assay) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0204"(deubiquitination reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26453728|imex:IM-28520-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:1343"(enzyme regulator) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 go:"GO:0004843"(thiol-dependent deubiquitinase) - no-uniprot-update: figure legend:Fig.2C,2D, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:OZXyibbzwpxPvDb/4xojppB2RWY false - binding-associated region:?-?|fluorescent dye label:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q6ZNK6 intact:EBI-4399559 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 dip:DIP-24261N psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:"MI:0998"(deubiquitinase assay) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0204"(deubiquitination reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26453728|imex:IM-28520-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:1343"(enzyme regulator) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 go:"GO:0004843"(thiol-dependent deubiquitinase) - no-uniprot-update: figure legend:Fig.2C,2D, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rigid:OZXyibbzwpxPvDb/4xojppB2RWY false - binding-associated region:?-?|tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q6ZNK6 uniprotkb:Q9Y4E8 intact:EBI-26453465|ensembl:ENSP00000440509|uniprotkb:Q5H8A9 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 psi-mi:tifab_human(display_long)|uniprotkb:TIFAB(gene name)|psi-mi:TIFAB(display_short)|uniprotkb:TIFA-like protein(gene name synonym) psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:"MI:0998"(deubiquitinase assay) Niederkorn et al. (2020) pubmed:32101751|imex:IM-28520 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0204"(deubiquitination reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-26453728|imex:IM-28520-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:1343"(enzyme regulator) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000255833(gene)|ensembl:ENST00000537858(transcript)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021650"(vestibulocochlear nerve formation)|go:"GO:0030432"(peristalsis)|go:"GO:0031223"(auditory behavior)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0048634"(regulation of muscle organ development)|go:"GO:0048806"(genitalia development)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071626"(mastication)|go:"GO:0090102"(cochlea development)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097094"(craniofacial suture morphogenesis)|go:"GO:0098583"(learned vocalization behavior)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1905747"(negative regulation of saliva secretion)|go:"GO:1905748"(hard palate morphogenesis)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR033621|go:"GO:0048839"(inner ear development)|refseq:NP_001092691.1 ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N go:"GO:0004843"(thiol-dependent deubiquitinase) - - figure legend:Fig.2C,2D, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/11/23 2020/11/24 rogid:2jyBW5zpHqIEVqGEH53XS4rc19M9606 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rigid:OZXyibbzwpxPvDb/4xojppB2RWY false - his tag:?-?|sumo tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)