#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569280|imex:IM-28590-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-plasma)|taxid:9606(homo sapiens blood plasma)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569293|imex:IM-28590-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:1D|caution:The figure legend text appears to have entered the antibody target  for capture and detection the wrong-way around.|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-plasma)|taxid:9606(homo sapiens blood plasma)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569321|imex:IM-28590-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:5|comment:non-reducing conditions|comment:Under nonreducing conditions, a characteristic ladder-like banding pattern is visible with all the oligomeric forms of ficolin-23.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-serum)|taxid:9606(Homo sapiens)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569425|imex:IM-28590-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:3, 5|comment:non-reducing conditions|comment:Under nonreducing conditions, a characteristic ladder-like banding pattern is visible with all the oligomeric forms of ficolin-23; high molecular mass oligomers are shown here.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-serum)|taxid:9606(Homo sapiens)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569325|imex:IM-28590-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:4C, 7C|antagonist:Collagenase|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569329|imex:IM-28590-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:4D|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569437|imex:IM-28590-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:5|comment:Under nonreducing conditions, a characteristic ladder-like banding pattern is visible with all the oligomeric forms of ficolin-23; high molecular mass oligomers are shown here.|comment:non-reducing conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569442|imex:IM-28590-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:5|comment:Under nonreducing conditions, a characteristic ladder-like banding pattern is visible with all the oligomeric forms of ficolin-23.|comment:non-reducing conditions.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569357|imex:IM-28590-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-serum)|taxid:9606(Homo sapiens)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569361|imex:IM-28590-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:1D|caution:The figure legend text appears to have entered the antibody target  for capture and detection the wrong-way around.|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-serum)|taxid:9606(Homo sapiens)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:Q15485	uniprotkb:O75636	intact:EBI-7468784|uniprotkb:A6NFG7|uniprotkb:Q9UC57|uniprotkb:Q6IS69|intact:MINT-5223224|uniprotkb:Q7M4P4|uniprotkb:A8K478|ensembl:ENSP00000291744	intact:EBI-11786958|uniprotkb:Q6IBJ5|uniprotkb:Q8WW86|ensembl:ENSP00000270879	psi-mi:fcn2_human(display_long)|uniprotkb:FCN2(gene name)|psi-mi:FCN2(display_short)|uniprotkb:FCNL(gene name synonym)|uniprotkb:Ficolin-B(gene name synonym)|uniprotkb:Ficolin-beta(gene name synonym)|uniprotkb:L-ficolin(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 2(gene name synonym)|uniprotkb:Serum lectin p35(gene name synonym)|uniprotkb:37 kDa elastin-binding protein(gene name synonym)|uniprotkb:EBP-37(gene name synonym)|uniprotkb:Hucolin(gene name synonym)	psi-mi:fcn3_human(display_long)|uniprotkb:FCN3(gene name)|psi-mi:FCN3(display_short)|uniprotkb:FCNH(gene name synonym)|uniprotkb:HAKA1(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing lectin 3 p35(gene name synonym)|uniprotkb:Collagen/fibrinogen domain-containing protein 3(gene name synonym)|uniprotkb:Hakata antigen(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Jarlhelt et al. (2020)	pubmed:32094208|imex:IM-28590	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26569458|imex:IM-28590-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004099.2|refseq:NP_056652.1|ensembl:ENSG00000160339(gene)|ensembl:ENST00000291744(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0008228"(opsonization)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:2001065"(mannan binding)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|mint:Q15485|rcsb pdb:2J0G|rcsb pdb:2J0H|rcsb pdb:2J0Y|rcsb pdb:2J1G|rcsb pdb:2J2P|rcsb pdb:2J3F|rcsb pdb:2J3G|rcsb pdb:2J3O|rcsb pdb:2J3U|rcsb pdb:2J61|rcsb pdb:4NYT|rcsb pdb:4R9J|rcsb pdb:4R9T|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	refseq:NP_003656.2|refseq:NP_775628.1|ensembl:ENSG00000142748(gene)|ensembl:ENST00000270879(transcript)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|go:"GO:1902679"(negative regulation of RNA biosynthetic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|rcsb pdb:1LA5|rcsb pdb:2J5Z|rcsb pdb:2J60|rcsb pdb:2J64|reactome:R-HSA-166662|reactome:R-HSA-166663|reactome:R-HSA-2855086	-	comment:mint|function:Calcium-dependent and GlcNAc-binding lectin. Enhanced phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region	-	figure legend:6|comment:A wide span of oligomeric forms was seen.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/21	2020/12/24	rogid:j6vRtYG3I6cn0c2TId/73bE/1To9606	rogid:Uqrs95TKW2LaGqmcRkU9cu3v2FA9606	rigid:Fv16MJpaHKB5ptBmCd1urqktgHg	false	-	-	-	-	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)