#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60701	uniprotkb:O60701	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501|ensembl:ENSP00000421757	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501|ensembl:ENSP00000421757	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:"MI:0071"(molecular sieving)	Hengel et al. (2020)	imex:IM-27731|pubmed:32001716	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25431855|imex:IM-27731-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814(gene)|ensembl:ENST00000316423(transcript)|ensembl:ENST00000506179(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599	refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814(gene)|ensembl:ENST00000316423(transcript)|ensembl:ENST00000506179(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599	-	-	-	figure legend:Fig. 3E|comment:delta132 and T325D mutants are an obligate hexamer and an obligate dimer respectively.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/20	2020/02/20	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	rigid:NIqu/OAAXJv+IfnvLqyySq+k9DY	false	mutation disrupting interaction strength:44-44(rs749975104)|mutation disrupting interaction strength:82-82|mutation disrupting interaction strength:325-325|mutation with no effect:132-132|his tag:n-n	mutation disrupting interaction strength:44-44(rs749975104)|mutation disrupting interaction strength:82-82|mutation disrupting interaction strength:325-325|mutation with no effect:132-132|his tag:n-n	6	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60701	uniprotkb:O60701	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501|ensembl:ENSP00000421757	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501|ensembl:ENSP00000421757	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:"MI:0071"(molecular sieving)	Hengel et al. (2020)	imex:IM-27731|pubmed:32001716	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25431886|imex:IM-27731-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814(gene)|ensembl:ENST00000316423(transcript)|ensembl:ENST00000506179(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599	refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814(gene)|ensembl:ENST00000316423(transcript)|ensembl:ENST00000506179(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599	-	-	-	figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/20	2020/02/20	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	rigid:NIqu/OAAXJv+IfnvLqyySq+k9DY	false	mutation:44-44|his tag:n-n	mutation:44-44|his tag:n-n	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60701	uniprotkb:O60701	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501|ensembl:ENSP00000421757	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501|ensembl:ENSP00000421757	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:"MI:0071"(molecular sieving)	Hengel et al. (2020)	imex:IM-27731|pubmed:32001716	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25431937|imex:IM-27731-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814(gene)|ensembl:ENST00000316423(transcript)|ensembl:ENST00000506179(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599	refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814(gene)|ensembl:ENST00000316423(transcript)|ensembl:ENST00000506179(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599	-	-	-	figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/20	2020/02/20	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	rigid:NIqu/OAAXJv+IfnvLqyySq+k9DY	false	mutation:325-325|his tag:n-n	mutation:325-325|his tag:n-n	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15846"	chebi:"CHEBI:18066"	intact:EBI-4399035	intact:EBI-25431969|chebi:"CHEBI:28532"|chebi:"CHEBI:27234"|chebi:"CHEBI:13498"|chebi:"CHEBI:13505"|chebi:"CHEBI:9845"|chebi:"CHEBI:9895"|chebi:"CHEBI:22103"	psi-mi:nad+(display_short)|psi-mi:"CHEBI:15846"(display_long)	psi-mi:udp-d-glucose(display_short)|psi-mi:"CHEBI:18066"(display_long)|intact:UDP-D-glucose(synonym)|intact:UDP-Glc(synonym)|intact:UDP-glucose(synonym)|intact:UDPglucose(synonym)|intact:"Uridine 5'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester"(synonym)|intact:"Uridine 5'-(trihydrogen diphosphate), P'-alpha-D-glucopyranosyl ester"(synonym)|intact:Uridine diphosphate glucose(synonym)|intact:uridinediphosphoglucose(synonym)|intact:uridine 5'-[3-D-glucopyranosyl dihydrogen diphosphate](iupac name)	psi-mi:"MI:0979"(oxidoreductase assay)	Hengel et al. (2020)	imex:IM-27731|pubmed:32001716	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25432004|imex:IM-27731-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)	-	-	figure legend:Table 2, Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	km:28.0x10^-6 ~6.8(molar)	2020/02/20	2020/03/03	-	-	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15846"	uniprotkb:O60701	intact:EBI-4399035	intact:EBI-353006|uniprotkb:O60589|uniprotkb:B3KUU2|uniprotkb:B4DN25|ensembl:ENSP00000319501|ensembl:ENSP00000421757	psi-mi:nad+(display_short)|psi-mi:"CHEBI:15846"(display_long)	psi-mi:ugdh_human(display_long)|uniprotkb:UGDH(gene name)|psi-mi:UGDH(display_short)	psi-mi:"MI:0979"(oxidoreductase assay)	Hengel et al. (2020)	imex:IM-27731|pubmed:32001716	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25432004|imex:IM-27731-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001171629.1|refseq:NP_001171630.1|refseq:NP_003350.1|ensembl:ENSG00000109814(gene)|ensembl:ENST00000316423(transcript)|ensembl:ENST00000506179(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0006065"(UDP-glucuronate biosynthetic process)|go:"GO:0015012"(heparan sulfate proteoglycan biosynthetic process)|go:"GO:0030206"(chondroitin sulfate biosynthetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001732(UDP-glucose/GDP-mannose dehydrogenase, N-terminal)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR014026(UDP-glucose/GDP-mannose dehydrogenase, dimerisation)|interpro:IPR014027(UDP-glucose/GDP-mannose dehydrogenase, C-terminal)|interpro:IPR017476(Nucleotide sugar dehydrogenase)|interpro:IPR028356|interpro:IPR036220|interpro:IPR036291|mint:O60701|rcsb pdb:2Q3E|rcsb pdb:2QG4|rcsb pdb:3ITK|rcsb pdb:3KHU|rcsb pdb:3PRJ|rcsb pdb:3PTZ|rcsb pdb:3TDK|rcsb pdb:3TF5|rcsb pdb:4EDF|rcsb pdb:4RJT|rcsb pdb:5TJH|rcsb pdb:5VR8|rcsb pdb:5W4X|rcsb pdb:6C4J|rcsb pdb:6C4K|rcsb pdb:6C58|rcsb pdb:6C5A|rcsb pdb:6C5Z|reactome:R-HSA-173599	go:"GO:0003979"(UDP-glucose 6-dehydrogenase activity)	-	-	figure legend:Table 2, Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	km:28.0x10^-6 ~6.8(molar)	2020/02/20	2020/03/03	-	rogid:FB1nDJFtfQk18OPze1TyR998SNk9606	-	false	-	mutation decreasing interaction rate:82-82|mutation decreasing interaction rate:44-44(rs749975104)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)