#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49788	uniprotkb:P20155	intact:EBI-25504187|ensembl:ENSP00000237696|uniprotkb:Q8N1D7	intact:EBI-10200479|uniprotkb:Q6FGH2|ensembl:ENSP00000248701	psi-mi:tig1_human(display_long)|uniprotkb:RARRES1(gene name)|psi-mi:RARRES1(display_short)|uniprotkb:PEIG1(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:Phorbol ester-induced gene 1 protein(gene name synonym)|uniprotkb:RAR-responsive protein TIG1(gene name synonym)|uniprotkb:Tazarotene-induced gene 1 protein(gene name synonym)	psi-mi:isk2_human(display_long)|uniprotkb:SPINK2(gene name)|psi-mi:SPINK2(display_short)|uniprotkb:Acrosin-trypsin inhibitor(gene name synonym)|uniprotkb:Epididymis tissue protein Li 172(gene name synonym)|uniprotkb:HUSI-II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shyu et al. (2018)	imex:IM-27868|pubmed:31886233	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25505083|imex:IM-27868-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000118849(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009684(Proteinase inhibitor I47, latexin)|interpro:IPR027261|ensembl:ENST00000237696(transcript)|refseq:NP_002879.2|refseq:NP_996846.1	refseq:NP_001258650.1|refseq:NP_001258651.1|refseq:NP_066937.1|ensembl:ENSG00000128040(gene)|ensembl:ENST00000248701(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0007286"(spermatid development)|go:"GO:1900004"(negative regulation of serine-type endopeptidase activity)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR036058|interpro:IPR042167|rcsb pdb:2JXD|rcsb pdb:6KBR	-	-	-	figure legend:3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line")	-	2020/04/06	2020/04/08	rogid:H/qZ2K2zU/neh7jxhOaxJz6knhw9606	rogid:zIpTsfygI9LJc0BSBjC8d4sDW1s9606	rigid:qtSkeoIK/Bce1jcruGoug2AKzeA	false	myc tag:?-?|his tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P20155	uniprotkb:P49788	intact:EBI-10200479|uniprotkb:Q6FGH2|ensembl:ENSP00000248701	intact:EBI-25504187|ensembl:ENSP00000237696|uniprotkb:Q8N1D7	psi-mi:isk2_human(display_long)|uniprotkb:SPINK2(gene name)|psi-mi:SPINK2(display_short)|uniprotkb:Acrosin-trypsin inhibitor(gene name synonym)|uniprotkb:Epididymis tissue protein Li 172(gene name synonym)|uniprotkb:HUSI-II(gene name synonym)	psi-mi:tig1_human(display_long)|uniprotkb:RARRES1(gene name)|psi-mi:RARRES1(display_short)|uniprotkb:PEIG1(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:Phorbol ester-induced gene 1 protein(gene name synonym)|uniprotkb:RAR-responsive protein TIG1(gene name synonym)|uniprotkb:Tazarotene-induced gene 1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shyu et al. (2018)	imex:IM-27868|pubmed:31886233	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25506907|imex:IM-27868-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001258650.1|refseq:NP_001258651.1|refseq:NP_066937.1|ensembl:ENSG00000128040(gene)|ensembl:ENST00000248701(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0007286"(spermatid development)|go:"GO:1900004"(negative regulation of serine-type endopeptidase activity)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR036058|interpro:IPR042167|rcsb pdb:2JXD|rcsb pdb:6KBR	ensembl:ENSG00000118849(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009684(Proteinase inhibitor I47, latexin)|interpro:IPR027261|ensembl:ENST00000237696(transcript)|refseq:NP_002879.2|refseq:NP_996846.1	-	-	myc-tag:?-?|his-tag:?-?	figure legend:3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line")	-	2020/04/06	2020/04/08	rogid:zIpTsfygI9LJc0BSBjC8d4sDW1s9606	rogid:H/qZ2K2zU/neh7jxhOaxJz6knhw9606	rigid:qtSkeoIK/Bce1jcruGoug2AKzeA	false	flag tag:n-n	myc tag:?-?|his tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P49788	uniprotkb:P20155	intact:EBI-25504187|ensembl:ENSP00000237696|uniprotkb:Q8N1D7	intact:EBI-10200479|uniprotkb:Q6FGH2|ensembl:ENSP00000248701	psi-mi:tig1_human(display_long)|uniprotkb:RARRES1(gene name)|psi-mi:RARRES1(display_short)|uniprotkb:PEIG1(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:Phorbol ester-induced gene 1 protein(gene name synonym)|uniprotkb:RAR-responsive protein TIG1(gene name synonym)|uniprotkb:Tazarotene-induced gene 1 protein(gene name synonym)	psi-mi:isk2_human(display_long)|uniprotkb:SPINK2(gene name)|psi-mi:SPINK2(display_short)|uniprotkb:Acrosin-trypsin inhibitor(gene name synonym)|uniprotkb:Epididymis tissue protein Li 172(gene name synonym)|uniprotkb:HUSI-II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shyu et al. (2018)	imex:IM-27868|pubmed:31886233	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25506835|imex:IM-27868-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000118849(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009684(Proteinase inhibitor I47, latexin)|interpro:IPR027261|ensembl:ENST00000237696(transcript)|refseq:NP_002879.2|refseq:NP_996846.1	refseq:NP_001258650.1|refseq:NP_001258651.1|refseq:NP_066937.1|ensembl:ENSG00000128040(gene)|ensembl:ENST00000248701(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0007286"(spermatid development)|go:"GO:1900004"(negative regulation of serine-type endopeptidase activity)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR036058|interpro:IPR042167|rcsb pdb:2JXD|rcsb pdb:6KBR	-	-	-	figure legend:3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line")	-	2020/04/06	2020/04/08	rogid:H/qZ2K2zU/neh7jxhOaxJz6knhw9606	rogid:zIpTsfygI9LJc0BSBjC8d4sDW1s9606	rigid:qtSkeoIK/Bce1jcruGoug2AKzeA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49788	uniprotkb:P20155	intact:EBI-25504187|ensembl:ENSP00000237696|uniprotkb:Q8N1D7	intact:EBI-10200479|uniprotkb:Q6FGH2|ensembl:ENSP00000248701	psi-mi:tig1_human(display_long)|uniprotkb:RARRES1(gene name)|psi-mi:RARRES1(display_short)|uniprotkb:PEIG1(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:Phorbol ester-induced gene 1 protein(gene name synonym)|uniprotkb:RAR-responsive protein TIG1(gene name synonym)|uniprotkb:Tazarotene-induced gene 1 protein(gene name synonym)	psi-mi:isk2_human(display_long)|uniprotkb:SPINK2(gene name)|psi-mi:SPINK2(display_short)|uniprotkb:Acrosin-trypsin inhibitor(gene name synonym)|uniprotkb:Epididymis tissue protein Li 172(gene name synonym)|uniprotkb:HUSI-II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Shyu et al. (2018)	imex:IM-27868|pubmed:31886233	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25506921|imex:IM-27868-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000118849(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009684(Proteinase inhibitor I47, latexin)|interpro:IPR027261|ensembl:ENST00000237696(transcript)|refseq:NP_002879.2|refseq:NP_996846.1	refseq:NP_001258650.1|refseq:NP_001258651.1|refseq:NP_066937.1|ensembl:ENSG00000128040(gene)|ensembl:ENST00000248701(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0007286"(spermatid development)|go:"GO:1900004"(negative regulation of serine-type endopeptidase activity)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR036058|interpro:IPR042167|rcsb pdb:2JXD|rcsb pdb:6KBR	-	-	-	figure legend:3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line")	-	2020/04/06	2020/04/08	rogid:H/qZ2K2zU/neh7jxhOaxJz6knhw9606	rogid:zIpTsfygI9LJc0BSBjC8d4sDW1s9606	rigid:qtSkeoIK/Bce1jcruGoug2AKzeA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49788	uniprotkb:P20155	intact:EBI-25504187|ensembl:ENSP00000237696|uniprotkb:Q8N1D7	intact:EBI-10200479|uniprotkb:Q6FGH2|ensembl:ENSP00000248701	psi-mi:tig1_human(display_long)|uniprotkb:RARRES1(gene name)|psi-mi:RARRES1(display_short)|uniprotkb:PEIG1(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:Phorbol ester-induced gene 1 protein(gene name synonym)|uniprotkb:RAR-responsive protein TIG1(gene name synonym)|uniprotkb:Tazarotene-induced gene 1 protein(gene name synonym)	psi-mi:isk2_human(display_long)|uniprotkb:SPINK2(gene name)|psi-mi:SPINK2(display_short)|uniprotkb:Acrosin-trypsin inhibitor(gene name synonym)|uniprotkb:Epididymis tissue protein Li 172(gene name synonym)|uniprotkb:HUSI-II(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Shyu et al. (2018)	imex:IM-27868|pubmed:31886233	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25506942|imex:IM-27868-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000118849(gene)|go:"GO:0005615"(extracellular space)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009684(Proteinase inhibitor I47, latexin)|interpro:IPR027261|ensembl:ENST00000237696(transcript)|refseq:NP_002879.2|refseq:NP_996846.1	refseq:NP_001258650.1|refseq:NP_001258651.1|refseq:NP_066937.1|ensembl:ENSG00000128040(gene)|ensembl:ENST00000248701(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0007286"(spermatid development)|go:"GO:1900004"(negative regulation of serine-type endopeptidase activity)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR036058|interpro:IPR042167|rcsb pdb:2JXD|rcsb pdb:6KBR	go:"GO:0097356"(perinucleolar compartment)	-	-	figure legend:4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nt2d1)|taxid:9606("human NTERA-2 d.D1 (NT2D1) testicular embryonal carcinoma cell line")	-	2020/04/06	2020/04/08	rogid:H/qZ2K2zU/neh7jxhOaxJz6knhw9606	rogid:zIpTsfygI9LJc0BSBjC8d4sDW1s9606	rigid:qtSkeoIK/Bce1jcruGoug2AKzeA	false	-	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)