#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5T440 uniprotkb:Q86U28 intact:EBI-10714899|ensembl:ENSP00000355672 intact:EBI-10258659|uniprotkb:Q8IYZ0|uniprotkb:A8K3W3|uniprotkb:Q96BB2|uniprotkb:G3V291|uniprotkb:A6NFF1|ensembl:ENSP00000452007 psi-mi:caf17_human(display_long)|uniprotkb:Iron-sulfur cluster assembly factor homolog(gene name synonym)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:C1orf69(gene name synonym) psi-mi:isca2_human(display_long)|uniprotkb:ISCA2(gene name)|psi-mi:ISCA2(display_short)|uniprotkb:HBLD1(gene name synonym)|uniprotkb:HESB-like domain-containing protein 1(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25299994|imex:IM-27948-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001010867.1|ensembl:ENSG00000181873(gene)|ensembl:ENST00000366711(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|interpro:IPR017703(Folate-binding, YgfZ)|interpro:IPR027266|rcsb pdb:6GEU|rcsb pdb:6QE3|rcsb pdb:6QE4 refseq:NP_001258936.1|refseq:NP_919255.2|ensembl:ENSG00000165898(gene)|ensembl:ENST00000556816(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409 - - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/06 rogid:20ToUTe4EoBuv31juWsDvsuyQY89606 rogid:mo3MO7EMxmzJkq9+UDuY2weFBpQ9606 rigid:tWywsnr0SRm4WTMDwCiw+kn2yD0 false his tag:n-n|sufficient binding region:31-356 his tag:n-n|sufficient binding region:44-154 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86U28 uniprotkb:Q86U28 intact:EBI-10258659|uniprotkb:Q8IYZ0|uniprotkb:A8K3W3|uniprotkb:Q96BB2|uniprotkb:G3V291|uniprotkb:A6NFF1|ensembl:ENSP00000452007 intact:EBI-10258659|uniprotkb:Q8IYZ0|uniprotkb:A8K3W3|uniprotkb:Q96BB2|uniprotkb:G3V291|uniprotkb:A6NFF1|ensembl:ENSP00000452007 psi-mi:isca2_human(display_long)|uniprotkb:ISCA2(gene name)|psi-mi:ISCA2(display_short)|uniprotkb:HBLD1(gene name synonym)|uniprotkb:HESB-like domain-containing protein 1(gene name synonym) psi-mi:isca2_human(display_long)|uniprotkb:ISCA2(gene name)|psi-mi:ISCA2(display_short)|uniprotkb:HBLD1(gene name synonym)|uniprotkb:HESB-like domain-containing protein 1(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25300019|imex:IM-27948-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001258936.1|refseq:NP_919255.2|ensembl:ENSG00000165898(gene)|ensembl:ENST00000556816(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409 refseq:NP_001258936.1|refseq:NP_919255.2|ensembl:ENSG00000165898(gene)|ensembl:ENST00000556816(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/06 rogid:mo3MO7EMxmzJkq9+UDuY2weFBpQ9606 rogid:mo3MO7EMxmzJkq9+UDuY2weFBpQ9606 rigid:f6wjppxcZowAMx+Q61sxeDJj57s false his tag:n-n|sufficient binding region:44-154 his tag:n-n|sufficient binding region:44-154 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:49601" uniprotkb:Q5T440 intact:EBI-11172266|chebi:"CHEBI:49600"|chebi:"CHEBI:21134"|chebi:"CHEBI:64605" intact:EBI-10714899|ensembl:ENSP00000355672 psi-mi:fe2s2 iron-sulfur cluster(display_short)|psi-mi:"CHEBI:49601"(display_long)|intact:2 iron, 2 sulfur cluster(synonym)|intact:[2Fe-2S] cluster(synonym) psi-mi:caf17_human(display_long)|uniprotkb:Iron-sulfur cluster assembly factor homolog(gene name synonym)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:C1orf69(gene name synonym) psi-mi:"MI:0966"(ultraviolet-visible spectroscopy) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25300202|imex:IM-27948-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001010867.1|ensembl:ENSG00000181873(gene)|ensembl:ENST00000366711(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|interpro:IPR017703(Folate-binding, YgfZ)|interpro:IPR027266|rcsb pdb:6GEU|rcsb pdb:6QE3|rcsb pdb:6QE4 - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/07 - rogid:20ToUTe4EoBuv31juWsDvsuyQY89606 - false binding-associated region:?-? his tag:n-n|sufficient binding region:31-356 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5T440 uniprotkb:Q86U28 intact:EBI-10714899|ensembl:ENSP00000355672 intact:EBI-10258659|uniprotkb:Q8IYZ0|uniprotkb:A8K3W3|uniprotkb:Q96BB2|uniprotkb:G3V291|uniprotkb:A6NFF1|ensembl:ENSP00000452007 psi-mi:caf17_human(display_long)|uniprotkb:Iron-sulfur cluster assembly factor homolog(gene name synonym)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:C1orf69(gene name synonym) psi-mi:isca2_human(display_long)|uniprotkb:ISCA2(gene name)|psi-mi:ISCA2(display_short)|uniprotkb:HBLD1(gene name synonym)|uniprotkb:HESB-like domain-containing protein 1(gene name synonym) psi-mi:"MI:0966"(ultraviolet-visible spectroscopy) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25300202|imex:IM-27948-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001010867.1|ensembl:ENSG00000181873(gene)|ensembl:ENST00000366711(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|interpro:IPR017703(Folate-binding, YgfZ)|interpro:IPR027266|rcsb pdb:6GEU|rcsb pdb:6QE3|rcsb pdb:6QE4 refseq:NP_001258936.1|refseq:NP_919255.2|ensembl:ENSG00000165898(gene)|ensembl:ENST00000556816(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409 - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/07 rogid:20ToUTe4EoBuv31juWsDvsuyQY89606 rogid:mo3MO7EMxmzJkq9+UDuY2weFBpQ9606 - false his tag:n-n|sufficient binding region:31-356 his tag:n-n|sufficient binding region:44-154|sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:49601" uniprotkb:Q86U28 intact:EBI-11172266|chebi:"CHEBI:49600"|chebi:"CHEBI:21134"|chebi:"CHEBI:64605" intact:EBI-10258659|uniprotkb:Q8IYZ0|uniprotkb:A8K3W3|uniprotkb:Q96BB2|uniprotkb:G3V291|uniprotkb:A6NFF1|ensembl:ENSP00000452007 psi-mi:fe2s2 iron-sulfur cluster(display_short)|psi-mi:"CHEBI:49601"(display_long)|intact:2 iron, 2 sulfur cluster(synonym)|intact:[2Fe-2S] cluster(synonym) psi-mi:isca2_human(display_long)|uniprotkb:ISCA2(gene name)|psi-mi:ISCA2(display_short)|uniprotkb:HBLD1(gene name synonym)|uniprotkb:HESB-like domain-containing protein 1(gene name synonym) psi-mi:"MI:0966"(ultraviolet-visible spectroscopy) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25300221|imex:IM-27948-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001258936.1|refseq:NP_919255.2|ensembl:ENSG00000165898(gene)|ensembl:ENST00000556816(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409 - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/07 - rogid:mo3MO7EMxmzJkq9+UDuY2weFBpQ9606 - false binding-associated region:?-? his tag:n-n|sufficient binding region:44-154|sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:49601" uniprotkb:Q86U28 intact:EBI-11172266|chebi:"CHEBI:49600"|chebi:"CHEBI:21134"|chebi:"CHEBI:64605" intact:EBI-10258659|uniprotkb:Q8IYZ0|uniprotkb:A8K3W3|uniprotkb:Q96BB2|uniprotkb:G3V291|uniprotkb:A6NFF1|ensembl:ENSP00000452007 psi-mi:fe2s2 iron-sulfur cluster(display_short)|psi-mi:"CHEBI:49601"(display_long)|intact:2 iron, 2 sulfur cluster(synonym)|intact:[2Fe-2S] cluster(synonym) psi-mi:isca2_human(display_long)|uniprotkb:ISCA2(gene name)|psi-mi:ISCA2(display_short)|uniprotkb:HBLD1(gene name synonym)|uniprotkb:HESB-like domain-containing protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25300239|imex:IM-27948-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001258936.1|refseq:NP_919255.2|ensembl:ENSG00000165898(gene)|ensembl:ENST00000556816(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409 - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/07 - rogid:mo3MO7EMxmzJkq9+UDuY2weFBpQ9606 - false binding-associated region:?-? sufficient binding region:44-154|his tag:n-n|sufficient binding region:?-? - 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5T440 uniprotkb:Q86U28 intact:EBI-10714899|ensembl:ENSP00000355672 intact:EBI-10258659|uniprotkb:Q8IYZ0|uniprotkb:A8K3W3|uniprotkb:Q96BB2|uniprotkb:G3V291|uniprotkb:A6NFF1|ensembl:ENSP00000452007 psi-mi:caf17_human(display_long)|uniprotkb:Iron-sulfur cluster assembly factor homolog(gene name synonym)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:C1orf69(gene name synonym) psi-mi:isca2_human(display_long)|uniprotkb:ISCA2(gene name)|psi-mi:ISCA2(display_short)|uniprotkb:HBLD1(gene name synonym)|uniprotkb:HESB-like domain-containing protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25300251|imex:IM-27948-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001010867.1|ensembl:ENSG00000181873(gene)|ensembl:ENST00000366711(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|interpro:IPR017703(Folate-binding, YgfZ)|interpro:IPR027266|rcsb pdb:6GEU|rcsb pdb:6QE3|rcsb pdb:6QE4 refseq:NP_001258936.1|refseq:NP_919255.2|ensembl:ENSG00000165898(gene)|ensembl:ENST00000556816(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409 - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/07 rogid:20ToUTe4EoBuv31juWsDvsuyQY89606 rogid:mo3MO7EMxmzJkq9+UDuY2weFBpQ9606 rigid:tWywsnr0SRm4WTMDwCiw+kn2yD0 false his tag:n-n|sufficient binding region:31-356|mutation disrupting interaction strength:146-146 his tag:n-n|sufficient binding region:44-154 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:49601" uniprotkb:Q5T440 intact:EBI-11172266|chebi:"CHEBI:49600"|chebi:"CHEBI:21134"|chebi:"CHEBI:64605" intact:EBI-10714899|ensembl:ENSP00000355672 psi-mi:fe2s2 iron-sulfur cluster(display_short)|psi-mi:"CHEBI:49601"(display_long)|intact:2 iron, 2 sulfur cluster(synonym)|intact:[2Fe-2S] cluster(synonym) psi-mi:caf17_human(display_long)|uniprotkb:Iron-sulfur cluster assembly factor homolog(gene name synonym)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:C1orf69(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25300265|imex:IM-27948-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001010867.1|ensembl:ENSG00000181873(gene)|ensembl:ENST00000366711(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|interpro:IPR017703(Folate-binding, YgfZ)|interpro:IPR027266|rcsb pdb:6GEU|rcsb pdb:6QE3|rcsb pdb:6QE4 - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/07 - rogid:20ToUTe4EoBuv31juWsDvsuyQY89606 - false binding-associated region:?-? his tag:n-n|sufficient binding region:31-356|mutation disrupting interaction strength:146-146 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5T440 uniprotkb:Q86U28 intact:EBI-10714899|ensembl:ENSP00000355672 intact:EBI-10258659|uniprotkb:Q8IYZ0|uniprotkb:A8K3W3|uniprotkb:Q96BB2|uniprotkb:G3V291|uniprotkb:A6NFF1|ensembl:ENSP00000452007 psi-mi:caf17_human(display_long)|uniprotkb:Iron-sulfur cluster assembly factor homolog(gene name synonym)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:C1orf69(gene name synonym) psi-mi:isca2_human(display_long)|uniprotkb:ISCA2(gene name)|psi-mi:ISCA2(display_short)|uniprotkb:HBLD1(gene name synonym)|uniprotkb:HESB-like domain-containing protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nasta et al. (2019) imex:IM-27948|pubmed:31831856 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25300265|imex:IM-27948-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001010867.1|ensembl:ENSG00000181873(gene)|ensembl:ENST00000366711(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|interpro:IPR017703(Folate-binding, YgfZ)|interpro:IPR027266|rcsb pdb:6GEU|rcsb pdb:6QE3|rcsb pdb:6QE4 refseq:NP_001258936.1|refseq:NP_919255.2|ensembl:ENSG00000165898(gene)|ensembl:ENST00000556816(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409 - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/01/06 2020/01/07 rogid:20ToUTe4EoBuv31juWsDvsuyQY89606 rogid:mo3MO7EMxmzJkq9+UDuY2weFBpQ9606 - false his tag:n-n|sufficient binding region:31-356|mutation disrupting interaction strength:146-146 his tag:n-n|sufficient binding region:44-154|sufficient binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)