#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43837-2	uniprotkb:P50213-PRO_0000014436	intact:EBI-725399|ensembl:ENSP00000370232	intact:EBI-25820746	psi-mi:o43837-2(display_long)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:p50213-pro_0000014436(display_long)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692055|wwpdb:6KDF|imex:IM-28302-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-725377(idh3b_human)|ensembl:ENST00000380851(transcript)|ensembl:ENSG00000101365(gene)|uniprotkb:O43837-2(isoform-parent)	intact:EBI-355999(chain-parent)	-	-	chain-seq-start:28|chain-seq-end:366	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/06/30	2020/08/31	rogid:MogbvdEMgzFrE+7kl0ndsuXXIeo9606	rogid:l69AXbvSOSzRiBDObkC0mBeQIUw9606	rigid:r1efklSSVFBXb0I7N9JJOF+esiQ	false	sufficient binding region:35-374	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15846"	uniprotkb:O43837-2	intact:EBI-4399035	intact:EBI-725399|ensembl:ENSP00000370232	psi-mi:nad+(display_short)|psi-mi:"CHEBI:15846"(display_long)	psi-mi:o43837-2(display_long)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692064|wwpdb:6kdy|imex:IM-28302-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-725377(idh3b_human)|ensembl:ENST00000380851(transcript)|ensembl:ENSG00000101365(gene)|uniprotkb:O43837-2(isoform-parent)	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/06/30	2020/08/31	-	rogid:MogbvdEMgzFrE+7kl0ndsuXXIeo9606	-	false	-	sufficient binding region:35-374	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15846"	uniprotkb:P50213-PRO_0000014436	intact:EBI-4399035	intact:EBI-25820746	psi-mi:nad+(display_short)|psi-mi:"CHEBI:15846"(display_long)	psi-mi:p50213-pro_0000014436(display_long)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692064|wwpdb:6kdy|imex:IM-28302-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-355999(chain-parent)	-	-	chain-seq-start:28|chain-seq-end:366	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/06/30	2020/08/31	-	rogid:l69AXbvSOSzRiBDObkC0mBeQIUw9606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:29108"	uniprotkb:O43837-2	intact:EBI-1169353	intact:EBI-725399|ensembl:ENSP00000370232	psi-mi:"calcium(2+)"(display_short)|psi-mi:"CHEBI:29108"(display_long)	psi-mi:o43837-2(display_long)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692074|wwpdb:6KDE|imex:IM-28302-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	wwpdb:6kde(identity)	intact:EBI-725377(idh3b_human)|ensembl:ENST00000380851(transcript)|ensembl:ENSG00000101365(gene)|uniprotkb:O43837-2(isoform-parent)	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/06/30	2020/08/31	-	rogid:MogbvdEMgzFrE+7kl0ndsuXXIeo9606	-	false	-	sufficient binding region:35-374	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:29108"	uniprotkb:P50213-PRO_0000014436	intact:EBI-1169353	intact:EBI-25820746	psi-mi:"calcium(2+)"(display_short)|psi-mi:"CHEBI:29108"(display_long)	psi-mi:p50213-pro_0000014436(display_long)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692074|wwpdb:6KDE|imex:IM-28302-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	wwpdb:6kde(identity)	intact:EBI-355999(chain-parent)	-	-	chain-seq-start:28|chain-seq-end:366	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/06/30	2020/08/31	-	rogid:l69AXbvSOSzRiBDObkC0mBeQIUw9606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16908"	uniprotkb:O43837-2	intact:EBI-4421847	intact:EBI-725399|ensembl:ENSP00000370232	psi-mi:nadh(display_short)|psi-mi:"CHEBI:16908"(display_long)	psi-mi:o43837-2(display_long)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692084|wwpdb:6ke3|imex:IM-28302-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	wwpdb:6kde(identity)	intact:EBI-725377(idh3b_human)|ensembl:ENST00000380851(transcript)|ensembl:ENSG00000101365(gene)|uniprotkb:O43837-2(isoform-parent)	-	-	-	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/06/30	2020/08/31	-	rogid:MogbvdEMgzFrE+7kl0ndsuXXIeo9606	-	false	-	sufficient binding region:35-374	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:16908"	uniprotkb:P50213-PRO_0000014436	intact:EBI-4421847	intact:EBI-25820746	psi-mi:nadh(display_short)|psi-mi:"CHEBI:16908"(display_long)	psi-mi:p50213-pro_0000014436(display_long)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692084|wwpdb:6ke3|imex:IM-28302-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	wwpdb:6kde(identity)	intact:EBI-355999(chain-parent)	-	-	chain-seq-start:28|chain-seq-end:366	figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/06/30	2020/08/31	-	rogid:l69AXbvSOSzRiBDObkC0mBeQIUw9606	-	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:30887"	uniprotkb:O43837-2	intact:EBI-25692123	intact:EBI-725399|ensembl:ENSP00000370232	psi-mi:isocitric acid(display_short)|psi-mi:"CHEBI:30887"(display_long)	psi-mi:o43837-2(display_long)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:"MI:0979"(oxidoreductase assay)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692112|imex:IM-28302-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:1100"(bioactive entity)	psi-mi:"MI:0326"(protein)	-	intact:EBI-725377(idh3b_human)|ensembl:ENST00000380851(transcript)|ensembl:ENSG00000101365(gene)|uniprotkb:O43837-2(isoform-parent)	go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")	-	-	figure legend:Table 2|kinetics:Vmax=2.8umol/mg/min|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/30	2020/08/31	-	rogid:MogbvdEMgzFrE+7kl0ndsuXXIeo9606	-	false	-	sufficient binding region:35-374	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:30887"	uniprotkb:P50213-PRO_0000014436	intact:EBI-25692123	intact:EBI-25820746	psi-mi:isocitric acid(display_short)|psi-mi:"CHEBI:30887"(display_long)	psi-mi:p50213-pro_0000014436(display_long)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)	psi-mi:"MI:0979"(oxidoreductase assay)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692112|imex:IM-28302-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:1100"(bioactive entity)	psi-mi:"MI:0326"(protein)	-	intact:EBI-355999(chain-parent)	go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")	-	chain-seq-start:28|chain-seq-end:366	figure legend:Table 2|kinetics:Vmax=2.8umol/mg/min|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/30	2020/08/31	-	rogid:l69AXbvSOSzRiBDObkC0mBeQIUw9606	-	false	-	-	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:30887"	uniprotkb:P50213-PRO_0000014436	intact:EBI-25692123	intact:EBI-25820746	psi-mi:isocitric acid(display_short)|psi-mi:"CHEBI:30887"(display_long)	psi-mi:p50213-pro_0000014436(display_long)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)	psi-mi:"MI:0979"(oxidoreductase assay)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692128|imex:IM-28302-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:1100"(bioactive entity)	psi-mi:"MI:0326"(protein)	-	intact:EBI-355999(chain-parent)	go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")	-	chain-seq-start:28|chain-seq-end:366	figure legend:Fig. 1, Table 1|kinetics:VMax =7.3 umol/mg/min.      VMax =13.1umol/mg/min in the presence of activators ADP and Citrate|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/30	2020/08/31	-	rogid:l69AXbvSOSzRiBDObkC0mBeQIUw9606	-	false	-	-	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:30887"	uniprotkb:P51553-PRO_0000014449	intact:EBI-25692123	intact:EBI-25820741	psi-mi:isocitric acid(display_short)|psi-mi:"CHEBI:30887"(display_long)	psi-mi:p51553-pro_0000014449(display_long)|uniprotkb:IDH3G(gene name)|psi-mi:IDH3G(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)	psi-mi:"MI:0979"(oxidoreductase assay)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692128|imex:IM-28302-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:1100"(bioactive entity)	psi-mi:"MI:0326"(protein)	-	intact:EBI-1210876(chain-parent)	go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")	-	chain-seq-start:40|chain-seq-end:393	figure legend:Fig. 1, Table 1|kinetics:VMax =7.3 umol/mg/min.      VMax =13.1umol/mg/min in the presence of activators ADP and Citrate|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/30	2020/08/31	-	rogid:+jHnGD8LQI0EK4k+9YmOTPKQ2LE9606	-	false	-	-	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:30887"	uniprotkb:O43837-2	intact:EBI-25692123	intact:EBI-725399|ensembl:ENSP00000370232	psi-mi:isocitric acid(display_short)|psi-mi:"CHEBI:30887"(display_long)	psi-mi:o43837-2(display_long)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:"MI:0979"(oxidoreductase assay)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692140|imex:IM-28302-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:1100"(bioactive entity)	psi-mi:"MI:0326"(protein)	-	intact:EBI-725377(idh3b_human)|ensembl:ENST00000380851(transcript)|ensembl:ENSG00000101365(gene)|uniprotkb:O43837-2(isoform-parent)	go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")	-	-	figure legend:Fig. 1, Table 1|kinetics:Vmax=20umol/mg/min|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/30	2020/08/31	-	rogid:MogbvdEMgzFrE+7kl0ndsuXXIeo9606	-	false	-	sufficient binding region:35-374	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:30887"	uniprotkb:P50213-PRO_0000014436	intact:EBI-25692123	intact:EBI-25820746	psi-mi:isocitric acid(display_short)|psi-mi:"CHEBI:30887"(display_long)	psi-mi:p50213-pro_0000014436(display_long)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)	psi-mi:"MI:0979"(oxidoreductase assay)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692140|imex:IM-28302-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:1100"(bioactive entity)	psi-mi:"MI:0326"(protein)	-	intact:EBI-355999(chain-parent)	go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")	-	chain-seq-start:28|chain-seq-end:366	figure legend:Fig. 1, Table 1|kinetics:Vmax=20umol/mg/min|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/30	2020/08/31	-	rogid:l69AXbvSOSzRiBDObkC0mBeQIUw9606	-	false	-	-	-	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:30887"	uniprotkb:P51553-PRO_0000014449	intact:EBI-25692123	intact:EBI-25820741	psi-mi:isocitric acid(display_short)|psi-mi:"CHEBI:30887"(display_long)	psi-mi:p51553-pro_0000014449(display_long)|uniprotkb:IDH3G(gene name)|psi-mi:IDH3G(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)	psi-mi:"MI:0979"(oxidoreductase assay)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25692140|imex:IM-28302-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:1100"(bioactive entity)	psi-mi:"MI:0326"(protein)	-	intact:EBI-1210876(chain-parent)	go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")	-	chain-seq-start:40|chain-seq-end:393	figure legend:Fig. 1, Table 1|kinetics:Vmax=20umol/mg/min|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/06/30	2020/08/31	-	rogid:+jHnGD8LQI0EK4k+9YmOTPKQ2LE9606	-	false	-	-	-	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43837-2	uniprotkb:P50213-PRO_0000014436	intact:EBI-725399|ensembl:ENSP00000370232	intact:EBI-25820746	psi-mi:o43837-2(display_long)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:p50213-pro_0000014436(display_long)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)	psi-mi:"MI:0071"(molecular sieving)	Sun et al. (2019)	pubmed:31515270|imex:IM-28302	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25744724|imex:IM-28302-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-725377(idh3b_human)|ensembl:ENST00000380851(transcript)|ensembl:ENSG00000101365(gene)|uniprotkb:O43837-2(isoform-parent)	intact:EBI-355999(chain-parent)	-	-	chain-seq-start:28|chain-seq-end:366	figure legend:Supp. Fig. 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2020/06/30	2020/08/31	rogid:MogbvdEMgzFrE+7kl0ndsuXXIeo9606	rogid:l69AXbvSOSzRiBDObkC0mBeQIUw9606	rigid:r1efklSSVFBXb0I7N9JJOF+esiQ	false	sufficient binding region:35-374	-	1	1	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)