#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02153-1 uniprotkb:Q02108-1 intact:EBI-25372164|ensembl:ENSP00000264424 intact:EBI-25372173|ensembl:ENSP00000296518|ensembl:ENSP00000412201|ensembl:ENSP00000421493|ensembl:ENSP00000424361|ensembl:ENSP00000426040 psi-mi:q02153-1(display_long)|uniprotkb:Guanylate cyclase soluble subunit beta-3(gene name synonym)|uniprotkb:Soluble guanylate cyclase small subunit(gene name synonym)|uniprotkb:GUCY1B1(gene name)|psi-mi:GUCY1B1(display_short)|uniprotkb:GUC1B3(gene name synonym)|uniprotkb:GUCSB3(gene name synonym)|uniprotkb:GUCY1B3(gene name synonym) psi-mi:q02108-1(display_long)|uniprotkb:Guanylate cyclase soluble subunit alpha-3(gene name synonym)|uniprotkb:Soluble guanylate cyclase large subunit(gene name synonym)|uniprotkb:GUCY1A1(gene name)|psi-mi:GUCY1A1(display_short)|uniprotkb:GUC1A3(gene name synonym)|uniprotkb:GUCSA3(gene name synonym)|uniprotkb:GUCY1A3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Kang et al. (2019) pubmed:31514202|imex:IM-27660 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-25372160|wwpdb:6JT0|emdb:EMD-9883|emdb:EMD-9886|imex:IM-27660-1|wwpdb:6JT2|emdb:EMD-9885 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6911707(isoform-parent)|ensembl:ENSG00000061918(gene)|ensembl:ENST00000264424(transcript) intact:EBI-3910037(isoform-parent)|ensembl:ENSG00000164116(gene)|ensembl:ENST00000296518(transcript)|ensembl:ENST00000455639(transcript)|ensembl:ENST00000506455(transcript)|ensembl:ENST00000511108(transcript)|ensembl:ENST00000513574(transcript) - - - figure legend:Fig 1, Extended Data Fig 1-4, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2020/01/10 2020/01/10 rogid:XG3K0TurvMfAZcp1KXRsltIvuS49606 rogid:n1bJF3ineAG9xCfwUXgS4zrHlqA9606 rigid:2PBDpkKdUXn9fTwgbe1USkkjfKE false mutation:105-105 - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination) uniprotkb:Q02153-1 uniprotkb:Q02108-1 intact:EBI-25372164|ensembl:ENSP00000264424 intact:EBI-25372173|ensembl:ENSP00000296518|ensembl:ENSP00000412201|ensembl:ENSP00000421493|ensembl:ENSP00000424361|ensembl:ENSP00000426040 psi-mi:q02153-1(display_long)|uniprotkb:Guanylate cyclase soluble subunit beta-3(gene name synonym)|uniprotkb:Soluble guanylate cyclase small subunit(gene name synonym)|uniprotkb:GUCY1B1(gene name)|psi-mi:GUCY1B1(display_short)|uniprotkb:GUC1B3(gene name synonym)|uniprotkb:GUCSB3(gene name synonym)|uniprotkb:GUCY1B3(gene name synonym) psi-mi:q02108-1(display_long)|uniprotkb:Guanylate cyclase soluble subunit alpha-3(gene name synonym)|uniprotkb:Soluble guanylate cyclase large subunit(gene name synonym)|uniprotkb:GUCY1A1(gene name)|psi-mi:GUCY1A1(display_short)|uniprotkb:GUC1A3(gene name synonym)|uniprotkb:GUCSA3(gene name synonym)|uniprotkb:GUCY1A3(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Kang et al. (2019) pubmed:31514202|imex:IM-27660 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-25372186|wwpdb:6JT1|emdb:EMD-9884|imex:IM-27660-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6911707(isoform-parent)|ensembl:ENSG00000061918(gene)|ensembl:ENST00000264424(transcript) intact:EBI-3910037(isoform-parent)|ensembl:ENSG00000164116(gene)|ensembl:ENST00000296518(transcript)|ensembl:ENST00000455639(transcript)|ensembl:ENST00000506455(transcript)|ensembl:ENST00000511108(transcript)|ensembl:ENST00000513574(transcript) - - - figure legend:Fig 1, Extended Data Fig 1-4, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293f)|taxid:9606(Homo sapiens HEK293F cell line) - 2020/01/10 2020/01/10 rogid:XG3K0TurvMfAZcp1KXRsltIvuS49606 rogid:n1bJF3ineAG9xCfwUXgS4zrHlqA9606 rigid:2PBDpkKdUXn9fTwgbe1USkkjfKE false - - 1 1 psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:2287"(identification by structure determination)